| Type |
Details |
Score |
| Publication |
| First Author: |
Zhang Z |
| Year: |
2020 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Tissue-specific disruption of Kbtbd2 uncovers adipocyte-intrinsic and -extrinsic features of the teeny lipodystrophy syndrome. |
| Volume: |
117 |
| Issue: |
21 |
| Pages: |
11829-11835 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lania G |
| Year: |
2022 |
| Journal: |
Dis Model Mech |
| Title: |
A phenotypic rescue approach identifies lineage regionalization defects in a mouse model of DiGeorge syndrome. |
| Volume: |
15 |
| Issue: |
9 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Niu Z |
| Year: |
2008 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Serum response factor orchestrates nascent sarcomerogenesis and silences the biomineralization gene program in the heart. |
| Volume: |
105 |
| Issue: |
46 |
| Pages: |
17824-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jain R |
| Year: |
2011 |
| Journal: |
J Clin Invest |
| Title: |
Cardiac neural crest orchestrates remodeling and functional maturation of mouse semilunar valves. |
| Volume: |
121 |
| Issue: |
1 |
| Pages: |
422-30 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Carmona R |
| Year: |
2020 |
| Journal: |
Cells |
| Title: |
Contribution of a GATA4-Expressing Hematopoietic Progenitor Lineage to the Adult Mouse Endothelium. |
| Volume: |
9 |
| Issue: |
5 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Carmona R |
| Year: |
2020 |
| Journal: |
FASEB J |
| Title: |
Epicardial cell lineages and the origin of the coronary endothelium. |
| Volume: |
34 |
| Issue: |
4 |
| Pages: |
5223-5239 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cano E |
| Year: |
2016 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Extracardiac septum transversum/proepicardial endothelial cells pattern embryonic coronary arterio-venous connections. |
| Volume: |
113 |
| Issue: |
3 |
| Pages: |
656-61 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang J |
| Year: |
2010 |
| Journal: |
Dev Cell |
| Title: |
Bmp signaling regulates myocardial differentiation from cardiac progenitors through a MicroRNA-mediated mechanism. |
| Volume: |
19 |
| Issue: |
6 |
| Pages: |
903-12 |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Polr1a/Polr1a Tg(Mef2c-cre)2Blk/? |
| Background: |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6N |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Gt(ROSA)26Sor/Gt(ROSA)26Sor Tbx5/Tbx5<+> Tg(Mef2c-dre/ERT2)#Bbr/? |
| Background: |
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
823
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
715
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
822
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Carmona R |
| Year: |
2016 |
| Journal: |
Elife |
| Title: |
Conditional deletion of WT1 in the septum transversum mesenchyme causes congenital diaphragmatic hernia in mice. |
| Volume: |
5 |
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Varadkar P |
| Year: |
2008 |
| Journal: |
Dev Dyn |
| Title: |
Notch2 is required for the proliferation of cardiac neural crest-derived smooth muscle cells. |
| Volume: |
237 |
| Issue: |
4 |
| Pages: |
1144-52 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Takeuchi JK |
| Year: |
2011 |
| Journal: |
Nat Commun |
| Title: |
Chromatin remodelling complex dosage modulates transcription factor function in heart development. |
| Volume: |
2 |
|
| Pages: |
187 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Vincentz JW |
| Year: |
2021 |
| Journal: |
Dev Biol |
| Title: |
HAND transcription factors cooperatively specify the aorta and pulmonary trunk. |
| Volume: |
476 |
|
| Pages: |
1-10 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
De Bono C |
| Year: |
2018 |
| Journal: |
Hum Mol Genet |
| Title: |
T-box genes and retinoic acid signaling regulate the segregation of arterial and venous pole progenitor cells in the murine second heart field. |
| Volume: |
27 |
| Issue: |
21 |
| Pages: |
3747-3760 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Burns TA |
| Year: |
2019 |
| Journal: |
Anat Rec (Hoboken) |
| Title: |
A Novel Mouse Model for Cilia-Associated Cardiovascular Anomalies with a High Penetrance of Total Anomalous Pulmonary Venous Return. |
| Volume: |
302 |
| Issue: |
1 |
| Pages: |
136-145 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhang J |
| Year: |
2010 |
| Journal: |
Circ Res |
| Title: |
The FGF-BMP signaling axis regulates outflow tract valve primordium formation by promoting cushion neural crest cell differentiation. |
| Volume: |
107 |
| Issue: |
10 |
| Pages: |
1209-19 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Qyang Y |
| Year: |
2007 |
| Journal: |
Cell Stem Cell |
| Title: |
The renewal and differentiation of Isl1+ cardiovascular progenitors are controlled by a Wnt/beta-catenin pathway. |
| Volume: |
1 |
| Issue: |
2 |
| Pages: |
165-79 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Rana MS |
| Year: |
2014 |
| Journal: |
Circ Res |
| Title: |
Tbx1 coordinates addition of posterior second heart field progenitor cells to the arterial and venous poles of the heart. |
| Volume: |
115 |
| Issue: |
9 |
| Pages: |
790-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lewandowski SL |
| Year: |
2015 |
| Journal: |
J Biol Chem |
| Title: |
Histone Deacetylase 3 Coordinates Deacetylase-independent Epigenetic Silencing of Transforming Growth Factor-β1 (TGF-β1) to Orchestrate Second Heart Field Development. |
| Volume: |
290 |
| Issue: |
45 |
| Pages: |
27067-89 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sawada H |
| Year: |
2022 |
| Journal: |
Circulation |
| Title: |
Second Heart Field-Derived Cells Contribute to Angiotensin II-Mediated Ascending Aortopathies. |
| Volume: |
145 |
| Issue: |
13 |
| Pages: |
987-1001 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Stone OA |
| Year: |
2019 |
| Journal: |
Dev Cell |
| Title: |
Paraxial Mesoderm Is the Major Source of Lymphatic Endothelium. |
| Volume: |
50 |
| Issue: |
2 |
| Pages: |
247-255.e3 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Liu J |
| Year: |
2019 |
| Journal: |
PLoS Genet |
| Title: |
Gata4 regulates hedgehog signaling and Gata6 expression for outflow tract development. |
| Volume: |
15 |
| Issue: |
5 |
| Pages: |
e1007711 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhou L |
| Year: |
2017 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Gata4 potentiates second heart field proliferation and Hedgehog signaling for cardiac septation. |
| Volume: |
114 |
| Issue: |
8 |
| Pages: |
E1422-E1431 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ivins S |
| Year: |
2015 |
| Journal: |
Dev Cell |
| Title: |
The CXCL12/CXCR4 Axis Plays a Critical Role in Coronary Artery Development. |
| Volume: |
33 |
| Issue: |
4 |
| Pages: |
455-68 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ang SY |
| Year: |
2016 |
| Journal: |
Development |
| Title: |
KMT2D regulates specific programs in heart development via histone H3 lysine 4 di-methylation. |
| Volume: |
143 |
| Issue: |
5 |
| Pages: |
810-21 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Dilg D |
| Year: |
2016 |
| Journal: |
PLoS One |
| Title: |
HIRA Is Required for Heart Development and Directly Regulates Tnni2 and Tnnt3. |
| Volume: |
11 |
| Issue: |
8 |
| Pages: |
e0161096 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Page M |
| Year: |
2018 |
| Journal: |
PLoS One |
| Title: |
Loss of CXCL12/CXCR4 signalling impacts several aspects of cardiovascular development but does not exacerbate Tbx1 haploinsufficiency. |
| Volume: |
13 |
| Issue: |
11 |
| Pages: |
e0207251 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lin JI |
| Year: |
2020 |
| Journal: |
Commun Biol |
| Title: |
Mutation of LRP1 in cardiac neural crest cells causes congenital heart defects by perturbing outflow lengthening. |
| Volume: |
3 |
| Issue: |
1 |
| Pages: |
312 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Aanhaanen WT |
| Year: |
2011 |
| Journal: |
J Clin Invest |
| Title: |
Defective Tbx2-dependent patterning of the atrioventricular canal myocardium causes accessory pathway formation in mice. |
| Volume: |
121 |
| Issue: |
2 |
| Pages: |
534-44 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhang J |
| Year: |
2008 |
| Journal: |
Development |
| Title: |
Frs2alpha-deficiency in cardiac progenitors disrupts a subset of FGF signals required for outflow tract morphogenesis. |
| Volume: |
135 |
| Issue: |
21 |
| Pages: |
3611-22 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Serrano J |
| Year: |
2024 |
| Journal: |
Nat Commun |
| Title: |
The TAS1R2 G-protein-coupled receptor is an ambient glucose sensor in skeletal muscle that regulates NAD homeostasis and mitochondrial capacity. |
| Volume: |
15 |
| Issue: |
1 |
| Pages: |
4915 |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Polr1a/Polr1a Tg(Mef2c-cre)2Blk/? |
| Background: |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6N |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Polr1a/Polr1a Tg(Mef2c-cre)2Blk/? |
| Background: |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6N |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mitton KP |
| Year: |
2014 |
| Journal: |
Mol Vis |
| Title: |
Different effects of valproic acid on photoreceptor loss in Rd1 and Rd10 retinal degeneration mice. |
| Volume: |
20 |
|
| Pages: |
1527-44 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Guzzetta A |
| Year: |
2020 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Hedgehog-FGF signaling axis patterns anterior mesoderm during gastrulation. |
| Volume: |
117 |
| Issue: |
27 |
| Pages: |
15712-15723 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Goddeeris MM |
| Year: |
2008 |
| Journal: |
Development |
| Title: |
Intracardiac septation requires hedgehog-dependent cellular contributions from outside the heart. |
| Volume: |
135 |
| Issue: |
10 |
| Pages: |
1887-95 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Li D |
| Year: |
2019 |
| Journal: |
Development |
| Title: |
Planar cell polarity signaling regulates polarized second heart field morphogenesis to promote both arterial and venous pole septation. |
| Volume: |
146 |
| Issue: |
20 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Dong F |
| Year: |
2006 |
| Journal: |
Development |
| Title: |
Pitx2 promotes development of splanchnic mesoderm-derived branchiomeric muscle. |
| Volume: |
133 |
| Issue: |
24 |
| Pages: |
4891-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Adachi N |
| Year: |
2020 |
| Journal: |
Development |
| Title: |
Cardiopharyngeal mesoderm origins of musculoskeletal and connective tissues in the mammalian pharynx. |
| Volume: |
147 |
| Issue: |
3 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Martucciello S |
| Year: |
2020 |
| Journal: |
FASEB J |
| Title: |
A dual role for Tbx1 in cardiac lymphangiogenesis through genetic interaction with Vegfr3. |
| Volume: |
34 |
| Issue: |
11 |
| Pages: |
15062-15079 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hatley ME |
| Year: |
2012 |
| Journal: |
Cancer Cell |
| Title: |
A mouse model of rhabdomyosarcoma originating from the adipocyte lineage. |
| Volume: |
22 |
| Issue: |
4 |
| Pages: |
536-46 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Choudhary B |
| Year: |
2009 |
| Journal: |
Genesis |
| Title: |
Absence of TGFbeta signaling in embryonic vascular smooth muscle leads to reduced lysyl oxidase expression, impaired elastogenesis, and aneurysm. |
| Volume: |
47 |
| Issue: |
2 |
| Pages: |
115-21 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Das A |
| Year: |
2018 |
| Journal: |
Cell |
| Title: |
Impairment of an Endothelial NAD+-H2S Signaling Network Is a Reversible Cause of Vascular Aging. |
| Volume: |
173 |
| Issue: |
1 |
| Pages: |
74-89.e20 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Dykes IM |
| Year: |
2014 |
| Journal: |
Circ Res |
| Title: |
HIC2 is a novel dosage-dependent regulator of cardiac development located within the distal 22q11 deletion syndrome region. |
| Volume: |
115 |
| Issue: |
1 |
| Pages: |
23-31 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chang H |
| Year: |
2019 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Efficient genome-wide first-generation phenotypic screening system in mice using the piggyBac transposon. |
| Volume: |
116 |
| Issue: |
37 |
| Pages: |
18507-18516 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Frank DU |
| Year: |
2012 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Lethal arrhythmias in Tbx3-deficient mice reveal extreme dosage sensitivity of cardiac conduction system function and homeostasis. |
| Volume: |
109 |
| Issue: |
3 |
| Pages: |
E154-63 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Pollard AE |
| Year: |
2019 |
| Journal: |
Nat Metab |
| Title: |
AMPK activation protects against diet induced obesity through Ucp1-independent thermogenesis in subcutaneous white adipose tissue. |
| Volume: |
1 |
| Issue: |
3 |
| Pages: |
340-349 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ridge LA |
| Year: |
2021 |
| Journal: |
Cell Rep |
| Title: |
Dual role for CXCL12 signaling in semilunar valve development. |
| Volume: |
36 |
| Issue: |
8 |
| Pages: |
109610 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Eley L |
| Year: |
2018 |
| Journal: |
Elife |
| Title: |
A novel source of arterial valve cells linked to bicuspid aortic valve without raphe in mice. |
| Volume: |
7 |
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
En A |
| Year: |
2024 |
| Journal: |
Cell Rep |
| Title: |
Pervasive nuclear envelope ruptures precede ECM signaling and disease onset without activating cGAS-STING in Lamin-cardiomyopathy mice. |
| Volume: |
43 |
| Issue: |
6 |
| Pages: |
114284 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ducommun S |
| Year: |
2024 |
| Journal: |
Mol Metab |
| Title: |
Mustn1 is a smooth muscle cell-secreted microprotein that modulates skeletal muscle extracellular matrix composition. |
| Volume: |
82 |
|
| Pages: |
101912 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Liu K |
| Year: |
2022 |
| Journal: |
J Cell Biol |
| Title: |
Lineage tracing clarifies the cellular origin of tissue-resident macrophages in the developing heart. |
| Volume: |
221 |
| Issue: |
6 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Goddeeris MM |
| Year: |
2007 |
| Journal: |
Development |
| Title: |
Independent requirements for Hedgehog signaling by both the anterior heart field and neural crest cells for outflow tract development. |
| Volume: |
134 |
| Issue: |
8 |
| Pages: |
1593-604 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chen HI |
| Year: |
2014 |
| Journal: |
J Clin Invest |
| Title: |
VEGF-C and aortic cardiomyocytes guide coronary artery stem development. |
| Volume: |
124 |
| Issue: |
11 |
| Pages: |
4899-914 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Berry DC |
| Year: |
2016 |
| Journal: |
Nat Commun |
| Title: |
Mouse strains to study cold-inducible beige progenitors and beige adipocyte formation and function. |
| Volume: |
7 |
|
| Pages: |
10184 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Smallwood K |
| Year: |
2023 |
| Journal: |
Am J Hum Genet |
| Title: |
POLR1A variants underlie phenotypic heterogeneity in craniofacial, neural, and cardiac anomalies. |
| Volume: |
110 |
| Issue: |
5 |
| Pages: |
809-825 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hatzistergos KE |
| Year: |
2020 |
| Journal: |
Sci Adv |
| Title: |
A novel cardiomyogenic role for Isl1(+) neural crest cells in the inflow tract. |
| Volume: |
6 |
| Issue: |
49 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Devine WP |
| Year: |
2014 |
| Journal: |
Elife |
| Title: |
Early patterning and specification of cardiac progenitors in gastrulating mesoderm. |
| Volume: |
3 |
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
The Gene Expression Nervous System Atlas (GENSAT) Project, The Rockefeller University (New York, NY) |
| Year: |
2005 |
| Journal: |
Database Download |
| Title: |
MGI download of GENSAT transgene data |
|
|
|
|
•
•
•
•
•
|