Search our database by keyword

Examples

Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1601 to 1619 out of 1619 for Myo7a

<< First < Previous | Next > Last >>

0.022s

Type

Details

Score

Protein Domain

IPR037602 | USH1G_SAM

Type:

Domain

Description:

pre-mRNA splicing regulator USH1G (also known as SANS) is a multifunctional scaffold protein. It regulates Magi2-mediated endocytosis []and interacts with MYO7A and USH1C []. Mice lacking USH1G exhibit a loss of tip-links, defects in stereocilia morphology and organization, loss of mechanotransduction currents, and perturbations to hearing and balance []. Mutations in human USH1G gene cause Usher syndrome 1G (USH1G), a genetically heterogeneous condition characterised by the association of retinitis pigmentosa with sensorineural deafness []. USH1G has an N-terminal ankyrin repeat region and a C-terminal SAM domain []. The SAM domain is a putative protein-protein interaction domain.

•

Genotype

Symbol:	Myo7a/Myo7a<4626SB>
Background:	involves: BALB/c * 47BS/Rl * C3HeB/FeJ * CBA/Ca
Zygosity:	ht
Has Mutant Allele:	true

•

Genotype

Symbol:	Hprt1/Hprt1<+> Myo7a<4626SB>/Myo7a<4626SB>
Background:	involves: 129S7/SvEvBrd * BALB/cRl * C3H * C57BL/6J * CBA/Ca
Zygosity:	cx
Has Mutant Allele:	true

•

Publication

35962067 | J:345076

First Author:	Ballesteros A
Year:	2022
Journal:	Sci Rep
Title:	Selective binding and transport of protocadherin 15 isoforms by stereocilia unconventional myosins in a heterologous expression system.
Volume:	12
Issue:	1
Pages:	13764

•

Strain

MGI:3622653 | STOCK a/a Oca2<p-7R> Myo7a<sh1-6R>/In(7)4Rl +/R

Attribute String:

radiation induced mutation, inversion, mutant stock, chromosome aberration, chemically induced mutation

•

Publication

21709241 | J:174394

First Author:	Grati M
Year:	2011
Journal:	Proc Natl Acad Sci U S A
Title:	Myosin VIIa and sans localization at stereocilia upper tip-link density implicates these Usher syndrome proteins in mechanotransduction.
Volume:	108
Issue:	28
Pages:	11476-81

•

Publication

11138009 | J:66740

First Author:	Bolz H
Year:	2001
Journal:	Nat Genet
Title:	Mutation of CDH23, encoding a new member of the cadherin gene family, causes Usher syndrome type 1D.
Volume:	27
Issue:	1
Pages:	108-12

•

Publication

19457086 | J:150858

First Author:	Fernández-Medarde A
Year:	2009
Journal:	J Neurochem
Title:	RasGRF1 disruption causes retinal photoreception defects and associated transcriptomic alterations.
Volume:	110
Issue:	2
Pages:	641-52

•

Publication

24259566 | J:204163

First Author:	Gilels F
Year:	2013
Journal:	J Neurosci
Title:	Mutation of Foxo3 causes adult onset auditory neuropathy and alters cochlear synapse architecture in mice.
Volume:	33
Issue:	47
Pages:	18409-24

•

Publication

9070921 | J:38566

First Author:	Kelley PM
Year:	1997
Journal:	Genomics
Title:	The genomic structure of the gene defective in Usher syndrome type Ib (MYO7A).
Volume:	40
Issue:	1
Pages:	73-9

•

Publication

29167268 | J:256072

First Author:	Xiong A
Year:	2018
Journal:	J Biol Chem
Title:	The shaker-1 mouse myosin VIIa deafness mutation results in a severely reduced rate of the ATP hydrolysis step.
Volume:	293
Issue:	3
Pages:	819-829

•

Publication

29361540 | J:257650

First Author:	Liu Y
Year:	2018
Journal:	J Cell Sci
Title:	Unconventional myosin VIIA promotes melanoma progression.
Volume:	131
Issue:	4

•

Publication

33400922 | J:315709

First Author:	McGrath J
Year:	2021
Journal:	Curr Biol
Title:	Actin at stereocilia tips is regulated by mechanotransduction and ADF/cofilin.
Volume:	31
Issue:	6
Pages:	1141-1153.e7

•

Publication

21311020 | -

First Author:	Wu L
Year:	2011
Journal:	Science
Title:	Structure of MyTH4-FERM domains in myosin VIIa tail bound to cargo.
Volume:	331
Issue:	6018
Pages:	757-60

•

Publication

23457544 | J:197180

First Author:	Buniello A
Year:	2013
Journal:	PLoS One
Title:	Headbobber: a combined morphogenetic and cochleosaccular mouse model to study 10qter deletions in human deafness.
Volume:	8
Issue:	2
Pages:	e56274

•

Publication

- | J:350897

First Author:	Chang B
Year:	2024
Journal:	MGI Direct Data Submission
Title:	The retinal cone dysfunction mutation.

•

Publication

9171833 | J:40770

First Author:	Weil D
Year:	1997
Journal:	Nat Genet
Title:	The autosomal recessive isolated deafness, DFNB2, and the Usher 1B syndrome are allelic defects of the myosin-VIIA gene.
Volume:	16
Issue:	2
Pages:	191-3

•

Protein

Q80T11

Organism:	Mus musculus/domesticus
Length:	461
Fragment?:	false

•

Protein

Q0VBT9

Organism:	Mus musculus/domesticus
Length:	461
Fragment?:	false

•

Questions? Comments? Click here!

MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Your name:
Your email address:
Subject:
Message:	---- Current page: ---- /mousemine/keywordSearchResults.do?searchOffset=1600&searchTerm=Myo7a

MouseMine

Search our database by keyword

Examples

Search results 1601 to 1619 out of 1619 for Myo7a

Categories

Hits by Pathway

Hits by Category

Hits by Strain