|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1601 to 1665 out of 1665 for Nkx2-2

<< First    < Previous  |  Next >    Last >>
0.02s

Categories

Hits by Category

Hits by Strain

Type Details Score
GXD Expression    
Probe: MGI:6433769
Assay Type: RT-PCR
Annotation Date: 2020-06-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750326
Stage: TS26
Assay Id: MGI:6433810
Age: embryonic day 18.5
Image: S1
Specimen Label: e18.5 Nkx2.2 KO
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6433770
Assay Type: RT-PCR
Annotation Date: 2020-06-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750321
Stage: TS21
Assay Id: MGI:6433811
Age: embryonic day 13.5
Image: S1
Specimen Label: e13.5 Nkx2.2 KO
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6433770
Assay Type: RT-PCR
Annotation Date: 2020-06-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750326
Stage: TS26
Assay Id: MGI:6433811
Age: embryonic day 18.5
Image: S1
Specimen Label: e18.5 Nkx2.2 KO
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6433771
Assay Type: RT-PCR
Annotation Date: 2020-06-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750321
Stage: TS21
Assay Id: MGI:6433812
Age: embryonic day 13.5
Image: S1
Specimen Label: e13.5 Nkx2.2 KO
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6433771
Assay Type: RT-PCR
Annotation Date: 2020-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1750326
Stage: TS26
Assay Id: MGI:6433812
Age: embryonic day 18.5
Image: S1
Specimen Label: e18.5 Nkx2.2 KO
Detected: false
Specimen Num: 4
GXD Expression    
Probe: MGI:6433772
Assay Type: RT-PCR
Annotation Date: 2020-06-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750321
Stage: TS21
Assay Id: MGI:6433813
Age: embryonic day 13.5
Image: S1
Specimen Label: e13.5 Nkx2.2 KO
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6433772
Assay Type: RT-PCR
Annotation Date: 2020-06-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750326
Stage: TS26
Assay Id: MGI:6433813
Age: embryonic day 18.5
Image: S1
Specimen Label: e18.5 Nkx2.2 KO
Detected: true
Specimen Num: 4
Genotype
Symbol: Hoxb1/Hoxb1 Nkx2-2/Nkx2-2<+>
Background: involves: 129P2/OlaHsd * 129S2/SvPas
Zygosity: cn
Has Mutant Allele: true
GXD Expression
Probe: MGI:5780692
Assay Type: Immunohistochemistry
Annotation Date: 2016-07-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697417
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:5780714
Age: embryonic day 10.5
Image: 4J
Note: Expression is expanded and includes the Nkx2-2 domain.
Specimen Label: 4J
Detected: true
Specimen Num: 4
GXD Expression
Probe: MGI:5780692
Assay Type: Immunohistochemistry
Annotation Date: 2016-07-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697419
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:5780714
Age: embryonic day 11.5
Image: 4K
Note: Expression domain overlaps both domains of Nkx2-2 expression.
Specimen Label: 4K
Detected: true
Specimen Num: 5
GXD Expression
Probe: MGI:5780692
Assay Type: Immunohistochemistry
Annotation Date: 2016-07-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697420
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:5780714
Age: embryonic day 12.5
Image: 4L
Note: Expression domain is further expanded dorsally, nearly reaching the roof plate, and still overlaps both Nkx2-2 domains.
Specimen Label: 4L
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:5780692
Assay Type: Immunohistochemistry
Annotation Date: 2016-07-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:5780714
Age: embryonic day 15.5
Note: Authors state expression disappears from the Nkx2.2 domain.
Specimen Label: E15.5 not shown
Detected: true
Specimen Num: 8
GXD Expression
Probe: MGI:1338477
Assay Type: Immunohistochemistry
Annotation Date: 2019-08-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697417
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:6343553
Age: embryonic day 10.5
Image: 5C
Note: Expression was detected in the ventral midbrain. Co-expression with Nkx2-2 was progressively becoming restricted to the alar/basal plate boundary.
Specimen Label: 5C
Detected: true
Specimen Num: 7
GXD Expression
Probe: MGI:1338477
Assay Type: Immunohistochemistry
Annotation Date: 2019-08-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697419
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:6343553
Age: embryonic day 11.5
Image: 5E
Note: Expression was detected in the ventral midbrain. Co-expression with Nkx2-2 was progressively becoming restricted to the alar/basal plate boundary.
Specimen Label: 5E
Detected: true
Specimen Num: 9
GXD Expression
Probe: MGI:1338477
Assay Type: Immunohistochemistry
Annotation Date: 2019-08-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697420
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:6343553
Age: embryonic day 12.5
Image: 5G
Note: Expression was detected in the ventral midbrain. Co-expression with Nkx2-2 was progressively becoming restricted to the alar/basal plate boundary.
Specimen Label: 5G
Detected: true
Specimen Num: 11
Genotype
Symbol: Pax1/Pax1
Background: involves: C57BL/6 * CC57BR/MvY
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Pax1/Pax1<+>
Background: B6.CC57BR-Pax1
Zygosity: ht
Has Mutant Allele: true
GXD Expression
Probe: MGI:5780692
Assay Type: Immunohistochemistry
Annotation Date: 2016-07-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1614015
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:5780714
Age: embryonic day 9.5
Image: 4I
Note: Authors report expression overlaps with the Nkx2-2 domain.
Specimen Label: 4I
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:5780692
Assay Type: Immunohistochemistry
Annotation Date: 2016-07-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689617
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:5780714
Age: embryonic day 10.5
Image: 6D
Note: Region of expression overlaps with Nkx2-2 expression domains.
Specimen Label: 6D
Detected: true
Specimen Num: 19
GXD Expression
Probe: MGI:5780692
Assay Type: Immunohistochemistry
Annotation Date: 2016-07-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689619
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:5780714
Age: embryonic day 11.5
Image: 6H
Note: Some regions of expression overlap with Nkx2-2 expression domains.
Specimen Label: 6H
Detected: true
Specimen Num: 22
GXD Expression
Probe: MGI:5780692
Assay Type: Immunohistochemistry
Annotation Date: 2016-07-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689620
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:5780714
Age: embryonic day 12.5
Image: 6L
Note: Some regions of expression overlap with Nkx2-2 expression domains.
Specimen Label: 6L
Detected: true
Specimen Num: 25
Genotype
Symbol: Pax1/Pax1
Background: involves: C3HeB/FeJ * C57BL/6 * CC57BR/MvY
Zygosity: ht
Has Mutant Allele: true
GXD Expression
Probe: MGI:6455038
Assay Type: Immunohistochemistry
Annotation Date: 2002-09-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750323
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:2386026
Age: embryonic day 15.5
Image: 4A
Note: Authors report co-staining with islet cell precursor marker Nkx2.2
Specimen Label: 4A
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:2386007
Assay Type: Immunohistochemistry
Annotation Date: 2002-09-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750326
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:2386028
Age: embryonic day 18.5
Note: Authors report expression at levels equivalent to levels in wild-type littermates.
Specimen Label: Nkx2-2 -/- E18.5
Detected: true
Specimen Num: 5
GXD Expression
Probe: MGI:7531569
Assay Type: RNA in situ
Annotation Date: 2023-09-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3291317
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:7531574
Age: embryonic day 10.5
Image: 4D (bottom right)
Note: Expression partially overlaps with Nkx2-2 expression at ventral midline.
Specimen Label: 4D (bottom right)
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:28631
Assay Type: RNA in situ
Annotation Date: 1999-08-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616419
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:1342118
Age: embryonic day 11.5
Image: 3.D
Note: Expression was found in a single domain located in the ventral midline, in a similar location to Nkx2-2 expression in these embryos.
Specimen Label: 3.D
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:5586691
Assay Type: Immunohistochemistry
Annotation Date: 2020-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616419
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:6469355
Age: embryonic day 11.5
Image: 3K
Note: Expression domain adjacent to Nkx2.2 domain.
Specimen Label: 3K
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:5586691
Assay Type: Immunohistochemistry
Annotation Date: 2020-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616419
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:6469355
Age: embryonic day 11.5
Image: 3L
Note: Expression domain adjacent to Nkx2.2 domain.
Specimen Label: 3L
Detected: true
Specimen Num: 4
GXD Expression
Probe: MGI:6200636
Assay Type: Immunohistochemistry
Annotation Date: 2018-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1609217
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:6200651
Age: embryonic day 10.5
Image: 6q
Note: Knockout embryos show intermixing of Olig2 and Nkx2-2 progenitors.
Specimen Label: 6q
Detected: true
Specimen Num: 4
GXD Expression
Probe: MGI:6200636
Assay Type: Immunohistochemistry
Annotation Date: 2018-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1609217
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:6200651
Age: embryonic day 10.5
Image: 6v
Note: Knockout embryos show intermixing of Olig2 and Nkx2-2 progenitors.
Specimen Label: 6v
Detected: true
Specimen Num: 6
GXD Expression
Probe: MGI:2157975
Assay Type: RNA in situ
Annotation Date: 2002-03-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757720
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:2176523
Age: embryonic day 12.5
Image: 4F
Note: Expression detected in the ventral neuroepithelium of the spinal cord dorsal to Nkx2-2 positive cells.
Specimen Label: 4F
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:2157979
Assay Type: Immunohistochemistry
Annotation Date: 2002-03-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757720
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:2176565
Age: embryonic day 12.5
Image: 4C
Note: Expression is detected in the ventral neuroepithelium of the spinal cord and does not overlap with Nkx2-2 expression domain.
Specimen Label: 4C
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:2157971
Assay Type: RNA in situ
Annotation Date: 2002-03-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757727
Pattern: Uniform
Stage: TS27
Assay Id: MGI:2176469
Age: postnatal day 1
Image: 5G
Note: Nkx2-2 and Olig2 expression domains overlap at this stage.
Specimen Label: 5G
Detected: true
Specimen Num: 11
GXD Expression
Probe: MGI:2157971
Assay Type: RNA in situ
Annotation Date: 2002-03-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757727
Pattern: Uniform
Stage: TS27
Assay Id: MGI:2176469
Age: postnatal day 1
Image: 5H
Note: Nkx2-2 and Olig2 expression domains overlap at this stage.
Specimen Label: 5H
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:5694481
Assay Type: RNA in situ
Annotation Date: 2015-11-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757720
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:5694576
Age: embryonic day 12.5
Note: Expression was detected in the ventral neuroepithelium. Double labeling with Nkx2-2 showed adjacent, but non-overlapping domains.
Specimen Label: 2D
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5694481
Assay Type: RNA in situ
Annotation Date: 2015-11-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757720
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:5694576
Age: embryonic day 12.5
Note: Expression was detected in the ventral neuroepithelium. Double labeling with Nkx2-2 showed adjacent, but non-overlapping domains.
Specimen Label: 2H
Detected: true
Specimen Num: 2
Regulatory Region
Type: enhancer
Organism: mouse, laboratory
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Nkx2-2/Nkx2-2<+>
Background: involves: 129S6/SvEvTac * C57BL/6NCrl
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Nkx2-2/Nkx2-2
Background: involves: 129S6/SvEvTac * C57BL/6NCrl
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Nkx2-2/Nkx2-2
Background: involves: 129S6/SvEvTac * C57BL/6J
Zygosity: hm
Has Mutant Allele: true
HT Experiment
Series Id: GSE9619
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
HT Experiment
Series Id: GSE9603
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
HT Experiment
Series Id: E-GEOD-5126
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: GEO
HT Experiment  
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
HT Experiment  
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: ArrayExpress
HT Sample  
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 13.5
Stage: 21
Structure . Name: pancreas
Curation Status: Curated
HT Sample  
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 13.5
Stage: 21
Structure . Name: pancreas
Curation Status: Curated
HT Sample  
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 13.5
Stage: 21
Structure . Name: pancreas
Curation Status: Curated
HT Sample  
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 13.5
Stage: 21
Structure . Name: pancreas
Curation Status: Curated
HT Sample  
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 12.5
Stage: 20
Structure . Name: pancreas
Curation Status: Curated
HT Sample  
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 12.5
Stage: 20
Structure . Name: pancreas
Curation Status: Curated
HT Sample  
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 12.5
Stage: 20
Structure . Name: pancreas
Curation Status: Curated
HT Sample  
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 12.5
Stage: 20
Structure . Name: pancreas
Curation Status: Curated
HT Sample
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 13.5
Stage: 21
Structure . Name: pancreas
Notes: these alleles have been used in publications by these authors
Curation Status: Curated
HT Sample
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 13.5
Stage: 21
Structure . Name: pancreas
Notes: these alleles have been used in publications by these authors
Curation Status: Curated
HT Sample
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 13.5
Stage: 21
Structure . Name: pancreas
Notes: these alleles have been used in publications by these authors
Curation Status: Curated
HT Sample
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 13.5
Stage: 21
Structure . Name: pancreas
Notes: these alleles have been used in publications by these authors
Curation Status: Curated
HT Sample
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 13.5
Stage: 21
Structure . Name: pancreas
Notes: this allele has been used in publications by these authors
Curation Status: Curated
HT Sample
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 13.5
Stage: 21
Structure . Name: pancreas
Notes: this allele has been used in publications by these authors
Curation Status: Curated
HT Sample
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 13.5
Stage: 21
Structure . Name: pancreas
Notes: this allele has been used in publications by these authors
Curation Status: Curated
HT Sample
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 13.5
Stage: 21
Structure . Name: pancreas
Notes: this allele has been used in publications by these authors
Curation Status: Curated
Interaction Detail    
Role 2: prey
Type: physical
Role 1: bait
Name: Nkx2-2-Olig2
Relationship Type: physical association
Interaction Experiment
Description: Cross-repressive interaction of the Olig2 and Nkx2.2 transcription factors in developing neural tube associated with formation of a specific physical complex.
Interaction Detail    
Role 2: bait
Type: physical
Role 1: prey
Name: Nkx2-2-Olig2
Relationship Type: physical association
Interaction Experiment
Description: Nkx2.2 repressor complex regulates islet ?-cell specification and prevents ?-to-?-cell reprogramming.