Type |
Details |
Score |
Publication |
First Author: |
Patzak D |
Year: |
1999 |
Journal: |
Hum Genet |
Title: |
Identification, mapping, and genomic structure of a novel X-chromosomal human gene (SMPX) encoding a small muscular protein. |
Volume: |
105 |
Issue: |
5 |
Pages: |
506-12 |
|
•
•
•
•
•
|
Publication |
First Author: |
Palmer S |
Year: |
2001 |
Journal: |
J Cell Biol |
Title: |
The small muscle-specific protein Csl modifies cell shape and promotes myocyte fusion in an insulin-like growth factor 1-dependent manner. |
Volume: |
153 |
Issue: |
5 |
Pages: |
985-98 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
85
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang DZ |
Year: |
1999 |
Journal: |
Development |
Title: |
Requirement of a novel gene, Xin, in cardiac morphogenesis. |
Volume: |
126 |
Issue: |
6 |
Pages: |
1281-94 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
271
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
301
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
442
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
296
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
317
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
320
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
442
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
350
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
244
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
318
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
318
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Divine JK |
Year: |
2006 |
Journal: |
Am J Physiol Gastrointest Liver Physiol |
Title: |
Cooperative interactions among intestinal GATA factors in activating the rat liver fatty acid binding protein gene. |
Volume: |
291 |
Issue: |
2 |
Pages: |
G297-306 |
|
•
•
•
•
•
|
Publication |
First Author: |
Divine JK |
Year: |
2004 |
Journal: |
Am J Physiol Gastrointest Liver Physiol |
Title: |
GATA-4, GATA-5, and GATA-6 activate the rat liver fatty acid binding protein gene in concert with HNF-1alpha. |
Volume: |
287 |
Issue: |
5 |
Pages: |
G1086-99 |
|
•
•
•
•
•
|
Publication |
First Author: |
Guo M |
Year: |
2006 |
Journal: |
Int J Cancer |
Title: |
Hypermethylation of the GATA gene family in esophageal cancer. |
Volume: |
119 |
Issue: |
9 |
Pages: |
2078-83 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bélanger A |
Year: |
1986 |
Journal: |
J Steroid Biochem |
Title: |
Plasma levels of steroid glucuronides in prepubertal, adult and elderly men. |
Volume: |
24 |
Issue: |
5 |
Pages: |
1069-72 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhu W |
Year: |
2000 |
Journal: |
J Biol Chem |
Title: |
Functional analyses of three Csx/Nkx-2.5 mutations that cause human congenital heart disease. |
Volume: |
275 |
Issue: |
45 |
Pages: |
35291-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li H |
Year: |
2015 |
Journal: |
J Cell Biol |
Title: |
Endosomal sorting of Notch receptors through COMMD9-dependent pathways modulates Notch signaling. |
Volume: |
211 |
Issue: |
3 |
Pages: |
605-17 |
|
•
•
•
•
•
|
Publication |
First Author: |
Schindeler A |
Year: |
2005 |
Journal: |
Exp Cell Res |
Title: |
Muscle costameric protein, Chisel/Smpx, associates with focal adhesion complexes and modulates cell spreading in vitro via a Rac1/p38 pathway. |
Volume: |
307 |
Issue: |
2 |
Pages: |
367-80 |
|
•
•
•
•
•
|
Publication |
First Author: |
Schott JJ |
Year: |
1998 |
Journal: |
Science |
Title: |
Congenital heart disease caused by mutations in the transcription factor NKX2-5. |
Volume: |
281 |
Issue: |
5373 |
Pages: |
108-11 |
|
•
•
•
•
•
|
Publication |
First Author: |
Masaki H |
Year: |
2010 |
Journal: |
Genes Cells |
Title: |
DPPA4 modulates chromatin structure via association with DNA and core histone H3 in mouse embryonic stem cells. |
Volume: |
15 |
Issue: |
4 |
Pages: |
327-37 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
This entry represents the GATA family of transcription factors, such as GATA-4, GATA-5 and GATA-6. These transcription factors regulate critical steps of cellular differentiation during vertebrate development. GATA-4, 5 and 6 each contain two GATA-type zinc fingers, and are known to activate numerous enterocytic genes [, ]. Loss of GATA-4 and GATA-5 has been reported in human gastric and colon cancer []. GATA-4 binds to the consensus sequence 5'-AGATAG-3', and acts as a transcriptional activator of Anf in cooperation with Nkx2-5 []. It interacts with the homeobox domain of Nkx2-5 through its C-terminal zinc finger. It also interacts with Jarid2 which represses its ability to activate transcription of Anf. Defects in GATA-4 are the cause of atrial septal defect type 2 (ASD2) (OMIM:607941)[]. ASD2 is a congenital heart malformation characterised by incomplete closure of the wall between the atria resulting in blood flow from the left to the right atria.GATA-5 binds to the functionally important Cef-1 nuclear protein binding site in the cardiac-specific slow/cardiac troponin C transcriptional enhancer []. It may play an important role in the transcriptional program(s) that underlies smooth muscle cell diversity. |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Chisel protein plays a role in the regulatory network through which muscle cells coordinate their structural and functional states during growth, adaptation, and repair. The X-linked gene Chisel (Csl/Smpx) was first found expressed selectively in human cardiac and skeletal muscle cells []. It is expressed in embryos in sub-regions of the developing heart corresponding to the future chamber myocardium and in developing skeletal muscles []. It is a potential target of the cardiac homeodomain transcription factor Nkx2-5 []. It localises to the costameric cytoskeleton of muscle cells through its association with focal adhesion proteins, where it may participate in regulating the dynamics of actin through the Rac1/p38 kinase pathway []. |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Developmental pluripotency-associated protein 2 (Dppa2, also known as ECAT15-2) and Dppa4 (also known as ECAT15-1) have a common DNA binding domain known as the SAP motif. Dppa2 has been found to bind to the regulatory region of Nkx2-5 in embryonic stem (ES) cells []. Dppa4 has been found to bind to both DNA and histone H3 necessary for the chromatin structure resistance to MNase and for the proper localization of Dppa4 in ES cell nuclei []. |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Developmental pluripotency-associated protein 2 (Dppa2, also known as ECAT15-2) has a DNA binding domain known as the SAP motif. Dppa2 has been found to bind to the regulatory region of Nkx2-5 in embryonic stem (ES) cells []. |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Homeobox genes play fundamental roles in specifying cell fate and positional identity in embryos. Homeobox gene Csx/Nkx2.5, one of the vertebrate homologues of Drosophila tinman, is expressed in the precardiac mesoderm and in the myocardium of the embryonic and adult heart [, ]and is one of the master regulators of cardiac development, homeostasis and disease [, ]. Csx associates with the transcription factor GATA4 and this interaction may regulate a subset of cardiac muscle-specific genes []. Nkx2-5 regulates the gene encoding the Kcnh2 channel [].Mutations of the human Nkx2.5 gene cause congenital heart disease ASD7, characterised by incomplete closure of the wall between the atria [, , ]. |
|
•
•
•
•
•
|
Publication |
First Author: |
Han L |
Year: |
2023 |
Journal: |
Nat Cell Biol |
Title: |
Lipid droplet-associated lncRNA LIPTER preserves cardiac lipid metabolism. |
Volume: |
25 |
Issue: |
7 |
Pages: |
1033-1046 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hughes J |
Year: |
2019 |
Journal: |
Sci Rep |
Title: |
Maternal transmission of an Igf2r domain 11: IGF2 binding mutant allele (Igf2rI1565A) results in partial lethality, overgrowth and intestinal adenoma progression. |
Volume: |
9 |
Issue: |
1 |
Pages: |
11388 |
|
•
•
•
•
•
|
Publication |
First Author: |
Howell GR |
Year: |
2004 |
Journal: |
Genet Res |
Title: |
Identification of a cryptic lethal mutation in the mouse t(w73) haplotype. |
Volume: |
84 |
Issue: |
3 |
Pages: |
153-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tsuchihashi T |
Year: |
2011 |
Journal: |
Dev Biol |
Title: |
Hand2 function in second heart field progenitors is essential for cardiogenesis. |
Volume: |
351 |
Issue: |
1 |
Pages: |
62-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
The RIKEN BioResource Center |
Year: |
2006 |
Journal: |
Unpublished |
Title: |
Information obtained from The RIKEN BioResource Center |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Yin Z |
Year: |
2006 |
Journal: |
Am J Physiol Lung Cell Mol Physiol |
Title: |
Hop functions downstream of Nkx2.1 and GATA6 to mediate HDAC-dependent negative regulation of pulmonary gene expression. |
Volume: |
291 |
Issue: |
2 |
Pages: |
L191-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kwon C |
Year: |
2007 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Canonical Wnt signaling is a positive regulator of mammalian cardiac progenitors. |
Volume: |
104 |
Issue: |
26 |
Pages: |
10894-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Iyer LM |
Year: |
2018 |
Journal: |
Nucleic Acids Res |
Title: |
A context-specific cardiac β-catenin and GATA4 interaction influences TCF7L2 occupancy and remodels chromatin driving disease progression in the adult heart. |
Volume: |
46 |
Issue: |
6 |
Pages: |
2850-2867 |
|
•
•
•
•
•
|
Publication |
First Author: |
McFadden DG |
Year: |
2005 |
Journal: |
Development |
Title: |
The Hand1 and Hand2 transcription factors regulate expansion of the embryonic cardiac ventricles in a gene dosage-dependent manner. |
Volume: |
132 |
Issue: |
1 |
Pages: |
189-201 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhu Y |
Year: |
2008 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Tbx5-dependent pathway regulating diastolic function in congenital heart disease. |
Volume: |
105 |
Issue: |
14 |
Pages: |
5519-24 |
|
•
•
•
•
•
|
Publication |
First Author: |
Banerjee I |
Year: |
2014 |
Journal: |
PLoS Genet |
Title: |
Targeted ablation of nesprin 1 and nesprin 2 from murine myocardium results in cardiomyopathy, altered nuclear morphology and inhibition of the biomechanical gene response. |
Volume: |
10 |
Issue: |
2 |
Pages: |
e1004114 |
|
•
•
•
•
•
|
Publication |
First Author: |
Banerjee I |
Year: |
2012 |
Journal: |
Circ Res |
Title: |
Thymosin beta 4 is dispensable for murine cardiac development and function. |
Volume: |
110 |
Issue: |
3 |
Pages: |
456-64 |
|
•
•
•
•
•
|
Publication |
First Author: |
Saadane N |
Year: |
2000 |
Journal: |
Am J Physiol Heart Circ Physiol |
Title: |
Altered molecular response to adrenoreceptor-induced cardiac hypertrophy in Egr-1-deficient mice. |
Volume: |
278 |
Issue: |
3 |
Pages: |
H796-805 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mysliwiec MR |
Year: |
2011 |
Journal: |
J Biol Chem |
Title: |
Endothelial Jarid2/Jumonji is required for normal cardiac development and proper Notch1 expression. |
Volume: |
286 |
Issue: |
19 |
Pages: |
17193-204 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gaborit N |
Year: |
2012 |
Journal: |
Development |
Title: |
Cooperative and antagonistic roles for Irx3 and Irx5 in cardiac morphogenesis and postnatal physiology. |
Volume: |
139 |
Issue: |
21 |
Pages: |
4007-19 |
|
•
•
•
•
•
|
Publication |
First Author: |
Puskaric S |
Year: |
2010 |
Journal: |
Hum Mol Genet |
Title: |
Shox2 mediates Tbx5 activity by regulating Bmp4 in the pacemaker region of the developing heart. |
Volume: |
19 |
Issue: |
23 |
Pages: |
4625-33 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ismat FA |
Year: |
2005 |
Journal: |
Circ Res |
Title: |
Homeobox protein Hop functions in the adult cardiac conduction system. |
Volume: |
96 |
Issue: |
8 |
Pages: |
898-903 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xin M |
Year: |
2007 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Essential roles of the bHLH transcription factor Hrt2 in repression of atrial gene expression and maintenance of postnatal cardiac function. |
Volume: |
104 |
Issue: |
19 |
Pages: |
7975-80 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zheng X |
Year: |
2021 |
Journal: |
Front Cell Dev Biol |
Title: |
PDGFRα-Signaling Is Dispensable for the Development of the Sinoatrial Node After Its Fate Commitment. |
Volume: |
9 |
|
Pages: |
647165 |
|
•
•
•
•
•
|
Publication |
First Author: |
Delgado-OlguÃn P |
Year: |
2012 |
Journal: |
Nat Genet |
Title: |
Epigenetic repression of cardiac progenitor gene expression by Ezh2 is required for postnatal cardiac homeostasis. |
Volume: |
44 |
Issue: |
3 |
Pages: |
343-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Qiao Y |
Year: |
2017 |
Journal: |
Circ Res |
Title: |
Transient Notch Activation Induces Long-Term Gene Expression Changes Leading to Sick Sinus Syndrome in Mice. |
Volume: |
121 |
Issue: |
5 |
Pages: |
549-563 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bergstrom DE |
Year: |
2003 |
Journal: |
Mamm Genome |
Title: |
Overlapping deletions spanning the proximal two-thirds of the mouse t complex. |
Volume: |
14 |
Issue: |
12 |
Pages: |
817-29 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ho YS |
Year: |
2016 |
Journal: |
Stem Cells |
Title: |
Cardioprotective Actions of TGFβRI Inhibition Through Stimulating Autocrine/Paracrine of Survivin and Inhibiting Wnt in Cardiac Progenitors. |
Volume: |
34 |
Issue: |
2 |
Pages: |
445-55 |
|
•
•
•
•
•
|
Publication |
First Author: |
Harris LG |
Year: |
2016 |
Journal: |
Nucleic Acids Res |
Title: |
Evidence for a non-canonical role of HDAC5 in regulation of the cardiac Ncx1 and Bnp genes. |
Volume: |
44 |
Issue: |
8 |
Pages: |
3610-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jung-Ching Lin J |
Year: |
2005 |
Journal: |
J Med Sci |
Title: |
Structure, Expression, and Function of a Novel Intercalated Disc Protein, Xin. |
Volume: |
25 |
Issue: |
5 |
Pages: |
215-222 |
|
•
•
•
•
•
|
Allele |
Name: |
transgene insertion 9, Eric N Olson |
Allele Type: |
Transgenic |
Attribute String: |
Recombinase |
|
•
•
•
•
•
|
Publication |
First Author: |
Cardona M |
Year: |
2015 |
Journal: |
PLoS One |
Title: |
Executioner Caspase-3 and 7 Deficiency Reduces Myocyte Number in the Developing Mouse Heart. |
Volume: |
10 |
Issue: |
6 |
Pages: |
e0131411 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jones BT |
Year: |
2023 |
Journal: |
Genes Dev |
Title: |
Target-directed microRNA degradation regulates developmental microRNA expression and embryonic growth in mammals. |
Volume: |
37 |
Issue: |
13-14 |
Pages: |
661-674 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ye J |
Year: |
2013 |
Journal: |
J Cell Sci |
Title: |
A pathway involving HDAC5, cFLIP and caspases regulates expression of the splicing regulator polypyrimidine tract binding protein in the heart. |
Volume: |
126 |
Issue: |
Pt 7 |
Pages: |
1682-91 |
|
•
•
•
•
•
|
Strain |
Attribute String: |
targeted mutation, mutant stock |
|
•
•
•
•
•
|
Publication |
First Author: |
Kong Y |
Year: |
2001 |
Journal: |
Circulation |
Title: |
Cardiac-specific LIM protein FHL2 modifies the hypertrophic response to beta-adrenergic stimulation. |
Volume: |
103 |
Issue: |
22 |
Pages: |
2731-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Flachs P |
Year: |
2012 |
Journal: |
PLoS Genet |
Title: |
Interallelic and intergenic incompatibilities of the Prdm9 (Hst1) gene in mouse hybrid sterility. |
Volume: |
8 |
Issue: |
11 |
Pages: |
e1003044 |
|
•
•
•
•
•
|
Strain |
Attribute String: |
congenic, mutant strain, targeted mutation |
|
•
•
•
•
•
|
Publication |
First Author: |
Li Q |
Year: |
2012 |
Journal: |
J Biol Chem |
Title: |
Cited2 gene controls pluripotency and cardiomyocyte differentiation of murine embryonic stem cells through Oct4 gene. |
Volume: |
287 |
Issue: |
34 |
Pages: |
29088-100 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhu L |
Year: |
2007 |
Journal: |
Hum Mol Genet |
Title: |
Identification of a novel role of ZIC3 in regulating cardiac development. |
Volume: |
16 |
Issue: |
14 |
Pages: |
1649-60 |
|
•
•
•
•
•
|
Publication |
First Author: |
Samokhin AO |
Year: |
2018 |
Journal: |
Sci Transl Med |
Title: |
NEDD9 targets COL3A1 to promote endothelial fibrosis and pulmonary arterial hypertension. |
Volume: |
10 |
Issue: |
445 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Jesty SA |
Year: |
2012 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
c-kit+ precursors support postinfarction myogenesis in the neonatal, but not adult, heart. |
Volume: |
109 |
Issue: |
33 |
Pages: |
13380-5 |
|
•
•
•
•
•
|
Transgene |
Type: |
transgene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Allele |
Name: |
transgene insertion 2, Bruce Conklin |
Allele Type: |
Transgenic |
Attribute String: |
Reporter |
|
•
•
•
•
•
|
Strain |
Attribute String: |
transgenic, mutant stock |
|
•
•
•
•
•
|
Publication |
First Author: |
Teerawanichpan P |
Year: |
2007 |
Journal: |
Biochim Biophys Acta |
Title: |
Investigations of combinations of mutations in the jellyfish green fluorescent protein (GFP) that afford brighter fluorescence, and use of a version (VisGreen) in plant, bacterial, and animal cells. |
Volume: |
1770 |
Issue: |
9 |
Pages: |
1360-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
van Laake LW |
Year: |
2010 |
Journal: |
Circ Res |
Title: |
Reporter-based isolation of induced pluripotent stem cell- and embryonic stem cell-derived cardiac progenitors reveals limited gene expression variance. |
Volume: |
107 |
Issue: |
3 |
Pages: |
340-7 |
|
•
•
•
•
•
|
Allele |
Name: |
deletion, Chr 17, John C Schimenti 7 |
Allele Type: |
Radiation induced |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Allele |
Name: |
deletion, Chr 17, John C Schimenti 8 |
Allele Type: |
Radiation induced |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Allele |
Name: |
NK2 homeobox 5; targeted mutation 1.1, Mohammad Pashmforoush |
Allele Type: |
Targeted |
Attribute String: |
Conditional ready, No functional change |
|
•
•
•
•
•
|
Strain |
Attribute String: |
targeted mutation, mutant strain, congenic |
|
•
•
•
•
•
|
Strain |
Attribute String: |
congenic, mutant strain, targeted mutation |
|
•
•
•
•
•
|
Allele |
Name: |
NK2 homeobox 5; targeted mutation 1.1, William T Pu |
Allele Type: |
Targeted |
Attribute String: |
Inserted expressed sequence |
|
•
•
•
•
•
|
Allele |
Name: |
regulatory region 431; endonuclease-mediated mutation 1, David S Park |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Modified regulatory region |
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Regulatory Region |
Type: |
enhancer |
Organism: |
mouse, laboratory |
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Allele |
Name: |
transgene insertion 1, Sean Wu |
Allele Type: |
Transgenic |
Attribute String: |
Inducible, Recombinase, Reporter |
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Publication |
First Author: |
Hoelscher SC |
Year: |
2020 |
Journal: |
Int J Mol Sci |
Title: |
miR-128a Acts as a Regulator in Cardiac Development by Modulating Differentiation of Cardiac Progenitor Cell Populations. |
Volume: |
21 |
Issue: |
3 |
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Allele |
Name: |
NK2 homeobox 5; targeted mutation 2.1, Mauro W Costa |
Allele Type: |
Targeted |
Attribute String: |
Not Specified |
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Allele |
Name: |
NK2 homeobox 5; targeted mutation 3.1, Mauro W Costa |
Allele Type: |
Targeted |
Attribute String: |
Not Specified |
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Allele |
Name: |
regulatory region 125; endonuclease-mediated mutation 1, Tim Mohun |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Modified regulatory region |
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Allele |
Name: |
NK2 homeobox 5; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Recombinase |
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Strain |
Attribute String: |
coisogenic, mutant strain, endonuclease-mediated mutation |
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Allele |
Name: |
regulatory region 125; endonuclease-mediated mutation 2, Tim Mohun |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Modified regulatory region |
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Allele |
Name: |
transgene insertion, Tim Mohun |
Allele Type: |
Transgenic |
Attribute String: |
Inserted expressed sequence, Reporter |
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Allele |
Name: |
transgene insertion, Kyu-Ho Lee |
Allele Type: |
Transgenic |
Attribute String: |
Reporter |
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Allele |
Name: |
transgene insertion 12, Yumiko Saga |
Allele Type: |
Transgenic |
Attribute String: |
Conditional ready, Inserted expressed sequence, Reporter |
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Strain |
Attribute String: |
transgenic, mutant stock |
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Allele |
Name: |
transgene insertion 13, Yumiko Saga |
Allele Type: |
Transgenic |
Attribute String: |
Conditional ready, Inserted expressed sequence, Reporter |
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Strain |
Attribute String: |
transgenic, mutant stock |
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Allele |
Name: |
sweetheart long non-coding RNA; targeted mutation 1.1, Phillip Grote |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout |
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Genotype |
Symbol: |
Hand1/Hand1 Tg(Nkx2-5-cre)9Eno/? |
Background: |
either: (involves: 129S6/SvEvTac * Black Swiss) or (involves: 129S6/SvEvTac * C57BL/6) |
Zygosity: |
cn |
Has Mutant Allele: |
true |
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Genotype |
Symbol: |
Hand1/Hand1 Rr133/Rr133<+> Tg(Nkx2-5-cre)9Eno/? |
Background: |
either: (involves: 129S6/SvEvTac * Black Swiss) or (involves: 129S6/SvEvTac * C57BL/6) |
Zygosity: |
cn |
Has Mutant Allele: |
true |
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Genotype |
Symbol: |
Hand1/Hand1 Rr133/Rr133 Tg(Nkx2-5-cre)9Eno/? |
Background: |
either: (involves: 129S6/SvEvTac * Black Swiss) or (involves: 129S6/SvEvTac * C57BL/6) |
Zygosity: |
cn |
Has Mutant Allele: |
true |
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Genotype |
Symbol: |
Hey2/Hey2 Tg(Nkx2-5-cre)9Eno/? |
Background: |
involves: 129S6/SvEvTac * C57BL/6 * SJL |
Zygosity: |
cn |
Has Mutant Allele: |
true |
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Genotype |
Symbol: |
Hand2/Hand2 Tg(Nkx2-5-cre)9Eno/? |
Background: |
involves: 129 * 129S7/SvEvBrd * C57BL/6 |
Zygosity: |
cn |
Has Mutant Allele: |
true |
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Genotype |
Symbol: |
Gata4/Gata4 Tg(Nkx2-5-cre)9Eno/? |
Background: |
involves: 129 * C57BL/6 |
Zygosity: |
cn |
Has Mutant Allele: |
true |
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