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Search results 1601 to 1700 out of 1843 for Pomc

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Type Details Score
Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Pdpk1/Pdpk1 Tg(CAG-cat,-lacZ)11Miya/? Tg(Pomc1-cre)16Lowl/?
Background: involves: 129S4/SvJae * C57BL/6 * DBA/2 * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Pdpk1/Pdpk1 Tg(CAG-cat,-lacZ)11Miya/? Tg(Pomc1-cre)16Lowl/?
Background: involves: 129S4/SvJae * C57BL/6 * DBA/2 * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Htr2c/? Tg(Pomc1-cre)16Lowl/? Gt(ROSA)26Sor/Gt(ROSA)26Sor<+>
Background: involves: 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tbx3/Tbx3 Tg(Pomc1-cre)16Lowl/?
Background: involves: C57BL/6J
Zygosity: cn
Has Mutant Allele: true
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Publication
23576617 | J:198522
First Author: Byerly MS
Year: 2013
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Identification of hypothalamic neuron-derived neurotrophic factor as a novel factor modulating appetite.
Volume: 304
Issue: 12
Pages: R1085-95
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Publication
7988462 | J:43387
First Author: Bloomquist BT
Year: 1994
Journal: Endocrinology
Title: Regulated endocrine-specific protein-18: a short-lived novel glucocorticoid-regulated endocrine protein.
Volume: 135
Issue: 6
Pages: 2714-22
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Publication
19321449 | J:222151
First Author: Rambaud J
Year: 2009
Journal: J Biol Chem
Title: TIF1beta/KAP-1 is a coactivator of the orphan nuclear receptor NGFI-B/Nur77.
Volume: 284
Issue: 21
Pages: 14147-56
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Publication
7492314 | J:42694
 
First Author: Holthuis JC
Year: 1995
Journal: Biochem J
Title: Translocon-associated protein TRAP delta and a novel TRAP-like protein are coordinately expressed with pro-opiomelanocortin in Xenopus intermediate pituitary.
Volume: 312 ( Pt 1)
Pages: 205-13
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Publication
19150989 | J:146158
First Author: Seo S
Year: 2009
Journal: Hum Mol Genet
Title: Requirement of Bardet-Biedl syndrome proteins for leptin receptor signaling.
Volume: 18
Issue: 7
Pages: 1323-31
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Publication
25576055 | J:249436
First Author: Chen Y
Year: 2015
Journal: Diabetes
Title: Enhancement of hypothalamic STAT3 acetylation by nuclear receptor Nur77 dictates leptin sensitivity.
Volume: 64
Issue: 6
Pages: 2069-81
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Publication
32229232 | J:293151
 
First Author: Wasinski F
Year: 2020
Journal: Neuroscience
Title: Growth Hormone Receptor Deletion Reduces the Density of Axonal Projections from Hypothalamic Arcuate Nucleus Neurons.
Volume: 434
Pages: 136-147
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Publication
24812431 | J:229836
First Author: Weissmann L
Year: 2014
Journal: Diabetes
Title: IKKε is key to induction of insulin resistance in the hypothalamus, and its inhibition reverses obesity.
Volume: 63
Issue: 10
Pages: 3334-45
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Publication
19940178 | J:158472
First Author: Hawke Z
Year: 2009
Journal: J Neurosci
Title: PACAP neurons in the hypothalamic ventromedial nucleus are targets of central leptin signaling.
Volume: 29
Issue: 47
Pages: 14828-35
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Publication
12453895 | J:107169
First Author: Sainsbury A
Year: 2002
Journal: Diabetes
Title: Y2 receptor deletion attenuates the type 2 diabetic syndrome of ob/ob mice.
Volume: 51
Issue: 12
Pages: 3420-7
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Publication
10657504 | J:60515
First Author: Shen FS
Year: 1999
Journal: Neuropeptides
Title: Altered biosynthesis and secretion of pro-opiomelanocortin in the intermediate and anterior pituitary of carboxypeptidase E-deficient, Cpe(fat)/ Cpe(fat)mice.
Volume: 33
Issue: 4
Pages: 276-80
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Publication
20967882 | J:167571
First Author: Nilsson IA
Year: 2011
Journal: Glia
Title: Evidence of hypothalamic degeneration in the anorectic anx/anx mouse.
Volume: 59
Issue: 1
Pages: 45-57
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Publication
37542065 | J:340851
First Author: Ruggiero-Ruff RE
Year: 2023
Journal: Sci Rep
Title: Increased body weight in mice with fragile X messenger ribonucleoprotein 1 (Fmr1) gene mutation is associated with hypothalamic dysfunction.
Volume: 13
Issue: 1
Pages: 12666
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Publication
16141396 | J:129687
First Author: Chida D
Year: 2005
Journal: Endocrinology
Title: Involvement of corticotropin-releasing hormone- and interleukin (IL)-6-dependent proopiomelanocortin induction in the anterior pituitary during hypothalamic-pituitary-adrenal axis activation by IL-1alpha.
Volume: 146
Issue: 12
Pages: 5496-502
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Publication
14512435 | J:87425
First Author: Kariagina A
Year: 2004
Journal: Endocrinology
Title: Hypothalamic-pituitary cytokine network.
Volume: 145
Issue: 1
Pages: 104-12
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Publication
10792002 | J:111831
First Author: Muglia LJ
Year: 2000
Journal: J Clin Invest
Title: Corticotropin-releasing hormone links pituitary adrenocorticotropin gene expression and release during adrenal insufficiency.
Volume: 105
Issue: 9
Pages: 1269-77
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Publication
9699863 | J:121199
First Author: Reichardt HM
Year: 1998
Journal: J Steroid Biochem Mol Biol
Title: Analysis of glucocorticoid signalling by gene targeting.
Volume: 65
Issue: 1-6
Pages: 111-5
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Publication
16296893 | J:104063
First Author: Xu AW
Year: 2005
Journal: PLoS Biol
Title: Effects of hypothalamic neurodegeneration on energy balance.
Volume: 3
Issue: 12
Pages: e415
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Publication
9729427 | J:50229
First Author: Guan XM
Year: 1998
Journal: Brain Res Mol Brain Res
Title: Evidence of altered hypothalamic pro-opiomelanocortin/ neuropeptide Y mRNA expression in tubby mice.
Volume: 59
Issue: 2
Pages: 273-9
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Publication
25765155 | J:221121
 
First Author: Dey S
Year: 2015
Journal: Brain Res
Title: Erythropoietin negatively regulates pituitary ACTH secretion.
Volume: 1608
Pages: 14-20
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Publication
20810901 | J:164001
First Author: Dietrich MO
Year: 2010
Journal: J Neurosci
Title: Agrp neurons mediate Sirt1's action on the melanocortin system and energy balance: roles for Sirt1 in neuronal firing and synaptic plasticity.
Volume: 30
Issue: 35
Pages: 11815-25
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Publication
16825606 | J:127795
First Author: Luque RM
Year: 2006
Journal: Am J Physiol Endocrinol Metab
Title: Evidence that endogenous SST inhibits ACTH and ghrelin expression by independent pathways.
Volume: 291
Issue: 2
Pages: E395-403
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Publication
23835335 | J:208948
First Author: Ren H
Year: 2013
Journal: Diabetes
Title: Blunted refeeding response and increased locomotor activity in mice lacking FoxO1 in synapsin-Cre-expressing neurons.
Volume: 62
Issue: 10
Pages: 3373-83
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Publication
24996410 | J:323636
First Author: Torres-Andrade R
Year: 2014
Journal: Exp Physiol
Title: The increase in body weight induced by lack of methyl CpG binding protein-2 is associated with altered leptin signalling in the hypothalamus.
Volume: 99
Issue: 9
Pages: 1229-40
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Publication
27482817 | J:234171
First Author: Jacobs DT
Year: 2016
Journal: Dis Model Mech
Title: Dysfunction of intraflagellar transport-A causes hyperphagia-induced obesity and metabolic syndrome.
Volume: 9
Issue: 7
Pages: 789-98
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Publication
14636179 | J:103679
First Author: Jégou S
Year: 2003
Journal: J Neuroendocrinol
Title: Adenosine A2A receptor gene disruption provokes marked changes in melanocortin content and pro-opiomelanocortin gene expression.
Volume: 15
Issue: 12
Pages: 1171-7
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Publication
35800978 | J:350156
 
First Author: Berezin CT
Year: 2022
Journal: Neurobiol Sleep Circadian Rhythms
Title: Endogenous opioid signaling in the retina modulates sleep/wake activity in mice.
Volume: 13
Pages: 100078
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Publication
20068134 | J:164338
First Author: Reed AS
Year: 2010
Journal: Diabetes
Title: Functional role of suppressor of cytokine signaling 3 upregulation in hypothalamic leptin resistance and long-term energy homeostasis.
Volume: 59
Issue: 4
Pages: 894-906
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Publication
15841180 | J:97406
First Author: Choudhury AI
Year: 2005
Journal: J Clin Invest
Title: The role of insulin receptor substrate 2 in hypothalamic and beta cell function.
Volume: 115
Issue: 4
Pages: 940-50
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Publication
12072562 | J:77345
First Author: Sainsbury A
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Important role of hypothalamic Y2 receptors in body weight regulation revealed in conditional knockout mice.
Volume: 99
Issue: 13
Pages: 8938-43
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Publication
24027277 | J:201732
First Author: Harada H
Year: 2013
Journal: J Neurosci
Title: Deficiency of p62/Sequestosome 1 causes hyperphagia due to leptin resistance in the brain.
Volume: 33
Issue: 37
Pages: 14767-77
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Publication
19135134 | J:148970
First Author: Hisadome K
Year: 2009
Journal: Neuroscience
Title: 5-HT inhibition of rat insulin 2 promoter Cre recombinase transgene and proopiomelanocortin neuron excitability in the mouse arcuate nucleus.
Volume: 159
Issue: 1
Pages: 83-93
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Publication
35536884 | J:339272
First Author: Vagena E
Year: 2022
Journal: Sci Signal
Title: ASB4 modulates central melanocortinergic neurons and calcitonin signaling to control satiety and glucose homeostasis.
Volume: 15
Issue: 733
Pages: eabj8204
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Publication
9564824 | J:110689
First Author: Chesnokova V
Year: 1998
Journal: Endocrinology
Title: Murine leukemia inhibitory factor gene disruption attenuates the hypothalamo-pituitary-adrenal axis stress response.
Volume: 139
Issue: 5
Pages: 2209-16
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Publication
11089533 | J:65570
First Author: Chesnokova V
Year: 2000
Journal: Endocrinology
Title: Leukemia inhibitory factor mediates the hypothalamic pituitary adrenal axis response to inflammation.
Volume: 141
Issue: 11
Pages: 4032-40
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Publication
21738790 | J:174424
First Author: Wu D
Year: 2011
Journal: PLoS One
Title: Overexpression of SIRT1 in mouse forebrain impairs lipid/glucose metabolism and motor function.
Volume: 6
Issue: 6
Pages: e21759
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Publication
30500912 | J:269695
First Author: Loganathan N
Year: 2019
Journal: Endocrinology
Title: Bisphenol A Alters Bmal1, Per2, and Rev-Erba mRNA and Requires Bmal1 to Increase Neuropeptide Y Expression in Hypothalamic Neurons.
Volume: 160
Issue: 1
Pages: 181-192
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Publication
15016721 | J:105634
First Author: Halatchev IG
Year: 2004
Journal: Endocrinology
Title: Peptide YY3-36 inhibits food intake in mice through a melanocortin-4 receptor-independent mechanism.
Volume: 145
Issue: 6
Pages: 2585-90
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Publication
14559977 | J:125996
First Author: Arens J
Year: 2003
Journal: Physiol Genomics
Title: Age-dependent hypothalamic expression of neuropeptides in wild-type and melanocortin-4 receptor-deficient mice.
Volume: 16
Issue: 1
Pages: 38-46
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Publication
12644632 | J:84047
First Author: Weide K
Year: 2003
Journal: Physiol Genomics
Title: Hyperphagia, not hypometabolism, causes early onset obesity in melanocortin-4 receptor knockout mice.
Volume: 13
Issue: 1
Pages: 47-56
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Publication
15355324 | J:101295
First Author: Kurrikoff K
Year: 2004
Journal: Eur J Neurosci
Title: Deletion of the CCK2 receptor gene reduces mechanical sensitivity and abolishes the development of hyperalgesia in mononeuropathic mice.
Volume: 20
Issue: 6
Pages: 1577-86
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Publication
28580287 | J:350427
First Author: Loh K
Year: 2017
Journal: Mol Metab
Title: Insulin controls food intake and energy balance via NPY neurons.
Volume: 6
Issue: 6
Pages: 574-584
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Publication
9717839 | J:110599
First Author: Saiardi A
Year: 1998
Journal: Mol Endocrinol
Title: Absence of dopaminergic control on melanotrophs leads to Cushing's-like syndrome in mice.
Volume: 12
Issue: 8
Pages: 1133-9
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Publication
20107078 | J:157943
First Author: Tramullas M
Year: 2010
Journal: J Neurosci
Title: BAMBI (bone morphogenetic protein and activin membrane-bound inhibitor) reveals the involvement of the transforming growth factor-beta family in pain modulation.
Volume: 30
Issue: 4
Pages: 1502-11
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Publication
21642978 | J:173466
First Author: Purkayastha S
Year: 2011
Journal: Nat Med
Title: Uncoupling the mechanisms of obesity and hypertension by targeting hypothalamic IKK-β and NF-κB.
Volume: 17
Issue: 7
Pages: 883-7
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Publication
21266325 | J:170130
First Author: Claret M
Year: 2011
Journal: Diabetes
Title: Deletion of Lkb1 in pro-opiomelanocortin neurons impairs peripheral glucose homeostasis in mice.
Volume: 60
Issue: 3
Pages: 735-45
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Publication
32776827 | J:296861
First Author: Rastelli M
Year: 2020
Journal: Am J Physiol Endocrinol Metab
Title: Intestinal NAPE-PLD contributes to short-term regulation of food intake via gut-to-brain axis.
Volume: 319
Issue: 3
Pages: E647-E657
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Publication
31756168 | J:328910
First Author: Furigo IC
Year: 2020
Journal: J Mol Endocrinol
Title: STAT5 ablation in AgRP neurons increases female adiposity and blunts food restriction adaptations.
Volume: 64
Issue: 1
Pages: 13-27
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Publication
29031731 | J:262801
First Author: Collet TH
Year: 2017
Journal: Mol Metab
Title: Evaluation of a melanocortin-4 receptor (MC4R) agonist (Setmelanotide) in MC4R deficiency.
Volume: 6
Issue: 10
Pages: 1321-1329
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Publication
30709906 | J:280322
First Author: Wang Z
Year: 2019
Journal: J Biol Chem
Title: Age-dependent decline of hypothalamic HIF2α in response to insulin and its contribution to advanced age-associated metabolic disorders in mice.
Volume: 294
Issue: 13
Pages: 4946-4955
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Publication
9140068 | J:97838
First Author: Yamaguchi H
Year: 1996
Journal: Genes Cells
Title: Dopamine D2 receptor plays a critical role in cell proliferation and proopiomelanocortin expression in the pituitary.
Volume: 1
Issue: 2
Pages: 253-68
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Publication
22442070 | J:261701
First Author: Dicken MS
Year: 2012
Journal: J Neurosci
Title: Regulation of GABA and glutamate release from proopiomelanocortin neuron terminals in intact hypothalamic networks.
Volume: 32
Issue: 12
Pages: 4042-8
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Publication
27832201 | J:250783
First Author: Moreno CL
Year: 2016
Journal: PLoS One
Title: Role of Hypothalamic Creb-Binding Protein in Obesity and Molecular Reprogramming of Metabolic Substrates.
Volume: 11
Issue: 11
Pages: e0166381
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Publication
35537100 | J:325671
First Author: Wang Z
Year: 2022
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Transient receptor potential cation channel 6 deficiency leads to increased body weight and metabolic dysfunction.
Volume: 323
Issue: 1
Pages: R81-R97
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Publication
32891671 | J:298697
 
First Author: Fujima S
Year: 2020
Journal: Neurosci Lett
Title: CAPS2 deficiency induces proopiomelanocortin accumulation in pituitary and affects food intake behavior in mice.
Volume: 738
Pages: 135335
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Publication
28606559 | J:341465
 
First Author: Suyama S
Year: 2017
Journal: Neuropeptides
Title: Adiponectin at physiological level glucose-independently enhances inhibitory postsynaptic current onto NPY neurons in the hypothalamic arcuate nucleus.
Volume: 65
Pages: 1-9
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Publication
31009611 | J:283569
 
First Author: Lima LB
Year: 2019
Journal: Brain Res
Title: Relationship of α-MSH and AgRP axons to the perikarya of melanocortin-4 receptor neurons.
Volume: 1717
Pages: 136-146
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Publication
36593271 | J:341789
First Author: Liu H
Year: 2023
Journal: Nat Metab
Title: Hypothalamic Grb10 enhances leptin signalling and promotes weight loss.
Volume: 5
Issue: 1
Pages: 147-164
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Publication
32840013 | J:352370
First Author: Campos AMP
Year: 2020
Journal: J Neuroendocrinol
Title: Differences between rats and mice in the leptin action on the paraventricular nucleus of the hypothalamus: Implications for the regulation of the hypothalamic-pituitary-thyroid axis.
Volume: 32
Issue: 9
Pages: e12895
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Publication
32828307 | J:304246
First Author: Kagawa Y
Year: 2020
Journal: Biochem Biophys Res Commun
Title: Mitochondrial dysfunction in GnRH neurons impaired GnRH production.
Volume: 530
Issue: 1
Pages: 329-335
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Publication
25856311 | J:233518
First Author: Wee YS
Year: 2015
Journal: PLoS One
Title: Age-related onset of obesity corresponds with metabolic dysregulation and altered microglia morphology in mice deficient for Ifitm proteins.
Volume: 10
Issue: 4
Pages: e0123218
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Publication
25737949 | J:220979
First Author: Kim GH
Year: 2015
Journal: Mol Metab
Title: Leptin recruits Creb-regulated transcriptional coactivator 1 to improve hyperglycemia in insulin-deficient diabetes.
Volume: 4
Issue: 3
Pages: 227-36
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Publication
31995643 | J:350942
First Author: Idelevich A
Year: 2020
Journal: J Bone Miner Res
Title: Both NPY-Expressing and CART-Expressing Neurons Increase Energy Expenditure and Trabecular Bone Mass in Response to AP1 Antagonism, But Have Opposite Effects on Bone Resorption.
Volume: 35
Issue: 6
Pages: 1107-1118
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Publication
26610903 | J:228734
 
First Author: Ma S
Year: 2016
Journal: Neurosci Lett
Title: Transgenic n-3 PUFAs enrichment leads to weight loss via modulating neuropeptides in hypothalamus.
Volume: 611
Pages: 28-32
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Publication
29360543 | J:286359
 
First Author: Wang LA
Year: 2018
Journal: Neuropharmacology
Title: Coupling corticotropin-releasing-hormone and angiotensin converting enzyme 2 dampens stress responsiveness in male mice.
Volume: 133
Pages: 85-93
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Publication
28855710 | J:256340
First Author: Lau J
Year: 2017
Journal: Sci Rep
Title: GPR88 is a critical regulator of feeding and body composition in mice.
Volume: 7
Issue: 1
Pages: 9912
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Publication
24424036 | J:208815
First Author: Perez Millan MI
Year: 2014
Journal: Endocrinology
Title: Selective disruption of dopamine D2 receptors in pituitary lactotropes increases body weight and adiposity in female mice.
Volume: 155
Issue: 3
Pages: 829-39
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Publication
21664248 | J:183738
First Author: Ma QY
Year: 2011
Journal: Mol Cell Endocrinol
Title: Mimecan in pituitary corticotroph cells may regulate ACTH secretion and the HPAA.
Volume: 341
Issue: 1-2
Pages: 71-7
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Publication
32781065 | J:347681
 
First Author: Quaresma PGF
Year: 2020
Journal: Life Sci
Title: Cholinergic neurons in the hypothalamus and dorsal motor nucleus of the vagus are directly responsive to growth hormone.
Volume: 259
Pages: 118229
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Publication
36271117 | J:330634
First Author: Barahona MJ
Year: 2022
Journal: Sci Rep
Title: GLUT2 expression by glial fibrillary acidic protein-positive tanycytes is required for promoting feeding-response to fasting.
Volume: 12
Issue: 1
Pages: 17717
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Publication
33034617 | J:298848
 
First Author: Liu H
Year: 2021
Journal: Endocrinology
Title: TPH2 in the Dorsal Raphe Nuclei Regulates Energy Balance in a Sex-Dependent Manner.
Volume: 162
Issue: 1
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Publication
- | J:347398
     
First Author: Garrett L
Year: 2023
Journal: Neuroscience Applied
Title: GPR101 loss promotes insulin resistance and diet-induced obesity risk.
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Publication
39436109 | J:359299
First Author: Forzisi-Kathera-Ibarra E
Year: 2024
Journal: FASEB J
Title: KCNB1-Leptin receptor complexes couple electric and endocrine function in the melanocortin neurons of the hypothalamus.
Volume: 38
Issue: 20
Pages: e70111
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Publication
38531895 | J:346738
First Author: Minakhina S
Year: 2024
Journal: Sci Rep
Title: Regulation of hypothalamic reactive oxygen species and feeding behavior by phosphorylation of the beta 2 thyroid hormone receptor isoform.
Volume: 14
Issue: 1
Pages: 7200
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Publication
31917347 | J:291114
 
First Author: Li Y
Year: 2020
Journal: Neuroscience
Title: C1q/TNF-related Protein 4 Induces Signal Transducer and Activator of Transcription 3 Pathway and Modulates Food Intake.
Volume: 429
Pages: 1-9
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Publication
15591535 | J:222154
First Author: Martens C
Year: 2005
Journal: Mol Endocrinol
Title: Protein-protein interactions and transcriptional antagonism between the subfamily of NGFI-B/Nur77 orphan nuclear receptors and glucocorticoid receptor.
Volume: 19
Issue: 4
Pages: 885-97
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Publication
11756683 | J:73683
First Author: Shimokawa T
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Effect of a fatty acid synthase inhibitor on food intake and expression of hypothalamic neuropeptides.
Volume: 99
Issue: 1
Pages: 66-71
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Publication
10637296 | J:60366
First Author: Kuiper RP
Year: 2000
Journal: Mol Biol Cell
Title: Differential induction of two p24delta putative cargo receptors upon activation of a prohormone-producing cell.
Volume: 11
Issue: 1
Pages: 131-40
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Publication
11001766 | J:65222
First Author: Ziotopoulou M
Year: 2000
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