| Type |
Details |
Score |
| Publication |
| First Author: |
Lennon G |
| Year: |
1999 |
| Journal: |
Database Download |
| Title: |
WashU-HHMI Mouse EST Project |
|
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•
•
•
•
•
|
| Publication |
| First Author: |
MGI and IMPC |
| Year: |
2026 |
| Journal: |
Database Release |
| Title: |
MGI Load of Molecular Notes for Endonuclease-Mediated (CRISPR) Alleles from the International Mouse Phenotyping Consortium (IMPC) |
|
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•
•
•
•
•
|
| Publication |
| First Author: |
Hansen GM |
| Year: |
2008 |
| Journal: |
Genome Res |
| Title: |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. |
| Volume: |
18 |
| Issue: |
10 |
| Pages: |
1670-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
The Gene Ontology Consortium |
| Year: |
2014 |
|
| Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
|
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•
•
•
•
•
|
| Publication |
| First Author: |
Carninci P |
| Year: |
2005 |
| Journal: |
Science |
| Title: |
The transcriptional landscape of the mammalian genome. |
| Volume: |
309 |
| Issue: |
5740 |
| Pages: |
1559-63 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zambrowicz BP |
| Year: |
2003 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
| Volume: |
100 |
| Issue: |
24 |
| Pages: |
14109-14 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Adams DJ |
| Year: |
2024 |
| Journal: |
Nature |
| Title: |
Genetic determinants of micronucleus formation in vivo. |
| Volume: |
627 |
| Issue: |
8002 |
| Pages: |
130-136 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC) |
| Year: |
2014 |
| Journal: |
Database Release |
| Title: |
Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
| Year: |
2008 |
| Journal: |
Database Download |
| Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cyagen Biosciences Inc. |
| Year: |
2022 |
|
| Title: |
Cyagen Biosciences Website. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
GOA curators |
| Year: |
2016 |
|
| Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
| Year: |
2011 |
|
| Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
UniProt |
| Year: |
2021 |
|
| Title: |
Electronic Gene Ontology annotations created by ARBA machine learning models |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
| Year: |
2004 |
| Journal: |
Database Release |
| Title: |
Mouse T31 Radiation Hybrid Data Load |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2003 |
|
| Title: |
MGI Sequence Curation Reference |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Okazaki Y |
| Year: |
2002 |
| Journal: |
Nature |
| Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
| Volume: |
420 |
| Issue: |
6915 |
| Pages: |
563-73 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
GemPharmatech |
| Year: |
2020 |
|
| Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
The Gene Ontology Consortium |
| Year: |
2010 |
|
| Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
DDB, FB, MGI, GOA, ZFIN curators |
| Year: |
2001 |
|
| Title: |
Gene Ontology annotation through association of InterPro records with GO terms |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Diez-Roux G |
| Year: |
2011 |
| Journal: |
PLoS Biol |
| Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
| Volume: |
9 |
| Issue: |
1 |
| Pages: |
e1000582 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2010 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
MGI Genome Annotation Group and UniGene Staff |
| Year: |
2015 |
| Journal: |
Database Download |
| Title: |
MGI-UniGene Interconnection Effort |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2002 |
|
| Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
UniProt-GOA |
| Year: |
2012 |
|
| Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
| Year: |
2010 |
|
| Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
| Year: |
2000 |
| Journal: |
Database Release |
| Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
| Year: |
2010 |
| Journal: |
Database Download |
| Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Group |
| Year: |
2003 |
| Journal: |
Database Procedure |
| Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bairoch A |
| Year: |
1999 |
| Journal: |
Database Release |
| Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics |
| Year: |
2010 |
| Journal: |
Database Release |
| Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Allen Institute for Brain Science |
| Year: |
2004 |
| Journal: |
Allen Institute |
| Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
| UniProt Feature |
| Begin: |
140 |
| Description: |
Phosphoserine; by ATM, ATR and PRKDC |
| Type: |
modified residue |
| End: |
140 |
|
•
•
•
•
•
|
| Allele |
| Name: |
protein kinase, DNA activated, catalytic polypeptide; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
| UniProt Feature |
| Begin: |
473 |
| Description: |
Phosphoserine; by IKKE, MTOR, PRKDC and TBK1; alternate |
| Type: |
modified residue |
| End: |
473 |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
mutant strain, endonuclease-mediated mutation, congenic |
|
•
•
•
•
•
|
| Allele |
| Name: |
protein kinase, DNA activated, catalytic polypeptide; endonuclease-mediated mutation 1, Gemcro Inc |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
| DO Term |
|
•
•
•
•
•
|
| Allele |
| Name: |
protein kinase, DNA activated, catalytic polypeptide; mutation 1, Bruce Beutler |
| Allele Type: |
Chemically induced (ENU) |
|
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
congenic, mutant strain, endonuclease-mediated mutation |
|
•
•
•
•
•
|
| Allele |
| Name: |
protein kinase, DNA activated, catalytic polypeptide; transgene insertion 5-1, Laboratory of Molecular Biology |
| Allele Type: |
Transgenic |
| Attribute String: |
Hypomorph |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, chemically induced mutation, mutant strain |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, chemically induced mutation, mutant strain |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Prkdc/Prkdc |
| Background: |
C57BL/6J-Prkdc |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Prkdc/Prkdc |
| Background: |
involves: C57BL/6J |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Allele |
| Name: |
protein kinase, DNA activated, catalytic polypeptide; mutation 3, Bruce Beutler |
| Allele Type: |
Chemically induced (ENU) |
|
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Prkdc/? |
| Background: |
involves: FVB/N |
| Zygosity: |
ot |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Falck J |
| Year: |
2005 |
| Journal: |
Nature |
| Title: |
Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage. |
| Volume: |
434 |
| Issue: |
7033 |
| Pages: |
605-11 |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Domain |
| Description: |
This entry represents the C-terminal domain of ATRIP (ATR-interacting protein) found in vertebrates. The C-terminal domain contains a conserved EEXXXDDL motif (residues 769-776 in human ATRIP) that is essential for interaction with the catalytic subunit PRKDC and its recruitment to sites of DNA damage [].ATRIP is essential for DNA damage checkpoint signalling. The full-length protein forms a heterodimer with ATR kinase and is recruited to single-stranded DNA through interaction with RPA complexes [, ]. The ATR-ATRIP heterodimer binds the RPA complex and is recruited to single- stranded DNA during DNA damage response []. ATRIP localises to the nucleus and redistributes to discrete nuclear foci upon DNA damage []. The protein is phosphorylated by ATR and is required for ATR expression and stability []. |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
mutant strain, coisogenic, chemically induced mutation |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Prkdc/Prkdc |
| Background: |
C57BL/6J-Prkdc |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
47
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
180
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cortez D |
| Year: |
2001 |
| Journal: |
Science |
| Title: |
ATR and ATRIP: partners in checkpoint signaling. |
| Volume: |
294 |
| Issue: |
5547 |
| Pages: |
1713-6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bohnert BN |
| Year: |
2021 |
| Journal: |
Dis Model Mech |
| Title: |
Essential role of DNA-PKcs and plasminogen for the development of doxorubicin-induced glomerular injury in mice. |
| Volume: |
14 |
| Issue: |
9 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Fang J |
| Year: |
2023 |
| Journal: |
Nat Commun |
| Title: |
Genome-wide mapping of cancer dependency genes and genetic modifiers of chemotherapy in high-risk hepatoblastoma. |
| Volume: |
14 |
| Issue: |
1 |
| Pages: |
4003 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Abdul-Razak HH |
| Year: |
2018 |
| Journal: |
Sci Rep |
| Title: |
Molecular Evidence of Genome Editing in a Mouse Model of Immunodeficiency. |
| Volume: |
8 |
| Issue: |
1 |
| Pages: |
8214 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Abdulraouf A |
| Year: |
2026 |
| Journal: |
Nat Neurosci |
| Title: |
Optics-free spatial genomics for mapping mammalian brain aging by IRISeq. |
| Volume: |
29 |
| Issue: |
7 |
| Pages: |
1762-1773 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
785
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
758
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
585
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
585
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zou L |
| Year: |
2003 |
| Journal: |
Science |
| Title: |
Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes. |
| Volume: |
300 |
| Issue: |
5625 |
| Pages: |
1542-8 |
|
•
•
•
•
•
|