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Search results 1601 to 1700 out of 3238 for Psen1

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Type Details Score
Publication
First Author: Romano RA
Year: 2012
Journal: Development
Title: ΔNp63 knockout mice reveal its indispensable role as a master regulator of epithelial development and differentiation.
Volume: 139
Issue: 4
Pages: 772-82
Publication
First Author: Koo BK
Year: 2005
Journal: Development
Title: Mind bomb 1 is essential for generating functional Notch ligands to activate Notch.
Volume: 132
Issue: 15
Pages: 3459-70
Publication
First Author: Morello F
Year: 2020
Journal: Cell Rep
Title: Molecular Fingerprint and Developmental Regulation of the Tegmental GABAergic and Glutamatergic Neurons Derived from the Anterior Hindbrain.
Volume: 33
Issue: 2
Pages: 108268
Publication      
First Author: The Jackson Laboratory
Year: 2005
Journal: Unpublished
Title: Information obtained from The Jackson Laboratory, Bar Harbor, ME
Publication
First Author: Sundberg JP
Year: 2017
Journal: PLoS One
Title: Systematic screening for skin, hair, and nail abnormalities in a large-scale knockout mouse program.
Volume: 12
Issue: 7
Pages: e0180682
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication      
First Author: Freeman TC
Year: 1998
Journal: MGI Direct Data Submission
Title: Expression Mapping of Mouse Genes
Publication      
First Author: The Jackson Laboratory Backcross DNA Panel Mapping Resource
Year: 1999
Journal: Database Release
Title: JAX BSS Panel Mapping Data
Publication
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication      
First Author: The Jackson Laboratory
Year: 2012
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by The Jackson Laboratory
Publication        
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
Publication
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
Publication
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
Publication  
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
Publication      
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication        
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Publication        
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication  
First Author: Raia T
Year: 2023
Journal: Int J Mol Sci
Title: Perinatal S-Adenosylmethionine Supplementation Represses PSEN1 Expression by the Cellular Epigenetic Memory of CpG and Non-CpG Methylation in Adult TgCRD8 Mice.
Volume: 24
Issue: 14
UniProt Feature
Begin: 2162
Description: Potential nuclear localization signal for the C-terminal fragment generated by PSEN1
Type: short sequence motif
End: 2165
DO Term
Allele
Name: transgene insertion 1098, Martin Citron
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Publication
First Author: DeBay DR
Year: 2017
Journal: Alzheimers Dement (N Y)
Title: Targeting butyrylcholinesterase for preclinical single photon emission computed tomography (SPECT) imaging of Alzheimer's disease.
Volume: 3
Issue: 2
Pages: 166-176
Publication  
First Author: Park SY
Year: 2020
Journal: Cells
Title: SPON1 Can Reduce Amyloid Beta and Reverse Cognitive Impairment and Memory Dysfunction in Alzheimer's Disease Mouse Model.
Volume: 9
Issue: 5
Publication
First Author: Veeraraghavalu K
Year: 2010
Journal: J Neurosci
Title: Presenilin 1 mutants impair the self-renewal and differentiation of adult murine subventricular zone-neuronal progenitors via cell-autonomous mechanisms involving notch signaling.
Volume: 30
Issue: 20
Pages: 6903-15
Strain
Attribute String: transgenic, mutant strain, congenic
Allele
Name: transgene insertion 1, Martin Citron
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion 1274, Martin Citron
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion 24, GemPharmatech
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
Genotype
Symbol: Tg(PSEN1)1098Citr/?
Background: B6.FVB-Tg(PSEN1)1098Citr
Zygosity: ot
Has Mutant Allele: true
Publication
First Author: Lee JY
Year: 2020
Journal: Nat Commun
Title: N-AS-triggered SPMs are direct regulators of microglia in a model of Alzheimer's disease.
Volume: 11
Issue: 1
Pages: 2358
Publication
First Author: Veeraraghavalu K
Year: 2014
Journal: J Neurosci
Title: Age-dependent, non-cell-autonomous deposition of amyloid from synthesis of β-amyloid by cells other than excitatory neurons.
Volume: 34
Issue: 10
Pages: 3668-73
Publication
First Author: Moutinho M
Year: 2022
Journal: Sci Transl Med
Title: The niacin receptor HCAR2 modulates microglial response and limits disease progression in a mouse model of Alzheimer's disease.
Volume: 14
Issue: 637
Pages: eabl7634
Publication
First Author: Jay TR
Year: 2015
Journal: J Exp Med
Title: TREM2 deficiency eliminates TREM2+ inflammatory macrophages and ameliorates pathology in Alzheimer's disease mouse models.
Volume: 212
Issue: 3
Pages: 287-95
Publication
First Author: Bosch ME
Year: 2024
Journal: Mol Neurodegener
Title: Sodium oligomannate alters gut microbiota, reduces cerebral amyloidosis and reactive microglia in a sex-specific manner.
Volume: 19
Issue: 1
Pages: 18
Publication  
First Author: Lison H
Year: 2014
Journal: Neurobiol Dis
Title: Disrupted cross-laminar cortical processing in β amyloid pathology precedes cell death.
Volume: 63
Pages: 62-73
Allele
Name: transgene insertion S9, David R Borchelt
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
Publication  
First Author: Romero-Molina C
Year: 2024
Journal: Int J Mol Sci
Title: Autosomal Dominant Alzheimer's Disease Mutations in Human Microglia Are Not Sufficient to Trigger Amyloid Pathology in WT Mice but Might Affect Pathology in 5XFAD Mice.
Volume: 25
Issue: 5
Allele
Name: transgene insertion, Jill C Richardson
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
Allele
Name: transgene insertion 5, GemPharmatech Co., Ltd
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion 17, GemPharmatech
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
Publication
First Author: Lee JH
Year: 2022
Journal: Nat Neurosci
Title: Faulty autolysosome acidification in Alzheimer's disease mouse models induces autophagic build-up of Aβ in neurons, yielding senile plaques.
Volume: 25
Issue: 6
Pages: 688-701
Publication
First Author: Wang Y
Year: 2015
Journal: Cell
Title: TREM2 lipid sensing sustains the microglial response in an Alzheimer's disease model.
Volume: 160
Issue: 6
Pages: 1061-71
Publication
First Author: Yuan P
Year: 2016
Journal: Neuron
Title: TREM2 Haplodeficiency in Mice and Humans Impairs the Microglia Barrier Function Leading to Decreased Amyloid Compaction and Severe Axonal Dystrophy.
Volume: 90
Issue: 4
Pages: 724-39
GO Term
Publication
First Author: Kaji S
Year: 2024
Journal: Immunity
Title: Apolipoprotein E aggregation in microglia initiates Alzheimer's disease pathology by seeding β-amyloidosis.
Volume: 57
Issue: 11
Pages: 2651-2668.e12
Allele
Name: transgene insertion 6799, Robert Vassar
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
Publication
First Author: Janus C
Year: 2000
Journal: Neurobiol Aging
Title: Spatial learning in transgenic mice expressing human presenilin 1 (PS1) transgenes.
Volume: 21
Issue: 4
Pages: 541-9
Strain
Attribute String: congenic, mutant strain, transgenic
Allele
Name: transgene insertion, Laurent Pradier
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
Strain
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
Strain
Attribute String: coisogenic, mutant strain, transgenic
Strain
Attribute String: coisogenic, mutant strain, transgenic
Genotype
Symbol: Tg(PSEN1*L286V)1274Citr/?
Background: B6.FVB-Tg(PSEN1*L286V)1274Citr
Zygosity: ot
Has Mutant Allele: true
Publication
First Author: Li C
Year: 2024
Journal: Cell Death Dis
Title: GNG5 is a novel regulator of Aβ42 production in Alzheimer's disease.
Volume: 15
Issue: 11
Pages: 815
Publication
First Author: Cayzac S
Year: 2015
Journal: Neurobiol Aging
Title: Altered hippocampal information coding and network synchrony in APP-PS1 mice.
Volume: 36
Issue: 12
Pages: 3200-3213
Publication
First Author: Liu HL
Year: 2011
Journal: Behav Brain Res
Title: Treadmill exercise prevents decline in spatial learning and memory in APP/PS1 transgenic mice through improvement of hippocampal long-term potentiation.
Volume: 218
Issue: 2
Pages: 308-14
Publication
First Author: Lagadec S
Year: 2012
Journal: Neurobiol Aging
Title: Early temporal short-term memory deficits in double transgenic APP/PS1 mice.
Volume: 33
Issue: 1
Pages: 203.e1-11
Publication
First Author: Kuchibhotla KV
Year: 2008
Journal: Neuron
Title: Abeta plaques lead to aberrant regulation of calcium homeostasis in vivo resulting in structural and functional disruption of neuronal networks.
Volume: 59
Issue: 2
Pages: 214-25
Publication
First Author: Lee MK
Year: 1997
Journal: Nat Med
Title: Hyperaccumulation of FAD-linked presenilin 1 variants in vivo.
Volume: 3
Issue: 7
Pages: 756-60
Publication
First Author: Cirrito JR
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Serotonin signaling is associated with lower amyloid-β levels and plaques in transgenic mice and humans.
Volume: 108
Issue: 36
Pages: 14968-73
Genotype
Symbol: Tg(PSEN1dE9)S9Dbo/?
Background: involves: C3H/HeJ * C57BL/6J
Zygosity: ot
Has Mutant Allele: true
HT Experiment  
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
Publication
First Author: De Rossi P
Year: 2019
Journal: Brain Pathol
Title: Aberrant accrual of BIN1 near Alzheimer's disease amyloid deposits in transgenic models.
Volume: 29
Issue: 4
Pages: 485-501
Publication
First Author: Rosenzweig N
Year: 2024
Journal: Nat Med
Title: Sex-dependent APOE4 neutrophil-microglia interactions drive cognitive impairment in Alzheimer's disease.
Volume: 30
Issue: 10
Pages: 2990-3003
Publication
First Author: Ulland TK
Year: 2017
Journal: Cell
Title: TREM2 Maintains Microglial Metabolic Fitness in Alzheimer's Disease.
Volume: 170
Issue: 4
Pages: 649-663.e13
Publication
First Author: Kook SY
Year: 2014
Journal: Cell Death Differ
Title: Crucial role of calbindin-D28k in the pathogenesis of Alzheimer's disease mouse model.
Volume: 21
Issue: 10
Pages: 1575-87
Publication
First Author: Lin CJ
Year: 2023
Journal: Cell Rep
Title: Mast cell deficiency improves cognition and enhances disease-associated microglia in 5XFAD mice.
Volume: 42
Issue: 9
Pages: 113141
Publication
First Author: Evans AK
Year: 2024
Journal: J Neuroinflammation
Title: Impact of noradrenergic inhibition on neuroinflammation and pathophysiology in mouse models of Alzheimer's disease.
Volume: 21
Issue: 1
Pages: 322