| Type |
Details |
Score |
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1838
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1464
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1487
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1497
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1091
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1739
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Suen PW |
| Year: |
1999 |
| Journal: |
J Cell Sci |
| Title: |
Impaired integrin-mediated signal transduction, altered cytoskeletal structure and reduced motility in Hck/Fgr deficient macrophages. |
| Volume: |
112 ( Pt 22) |
|
| Pages: |
4067-78 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Souza CM |
| Year: |
2012 |
| Journal: |
J Biol Chem |
| Title: |
The phosphatase PTP-PEST/PTPN12 regulates endothelial cell migration and adhesion, but not permeability, and controls vascular development and embryonic viability. |
| Volume: |
287 |
| Issue: |
51 |
| Pages: |
43180-90 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Otero K |
| Year: |
2009 |
| Journal: |
Nat Immunol |
| Title: |
Macrophage colony-stimulating factor induces the proliferation and survival of macrophages via a pathway involving DAP12 and beta-catenin. |
| Volume: |
10 |
| Issue: |
7 |
| Pages: |
734-43 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Canobbio I |
| Year: |
2015 |
| Journal: |
Biochem J |
| Title: |
The focal adhesion kinase Pyk2 links Ca2+ signalling to Src family kinase activation and protein tyrosine phosphorylation in thrombin-stimulated platelets. |
| Volume: |
469 |
| Issue: |
2 |
| Pages: |
199-210 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Uehara S |
| Year: |
2017 |
| Journal: |
Sci Signal |
| Title: |
Protein kinase N3 promotes bone resorption by osteoclasts in response to Wnt5a-Ror2 signaling. |
| Volume: |
10 |
| Issue: |
494 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Rhee I |
| Year: |
2013 |
| Journal: |
Mol Cell Biol |
| Title: |
Macrophage fusion is controlled by the cytoplasmic protein tyrosine phosphatase PTP-PEST/PTPN12. |
| Volume: |
33 |
| Issue: |
12 |
| Pages: |
2458-69 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Balasubramanian S |
| Year: |
2012 |
| Journal: |
PLoS One |
| Title: |
?3 integrin in cardiac fibroblast is critical for extracellular matrix accumulation during pressure overload hypertrophy in mouse. |
| Volume: |
7 |
| Issue: |
9 |
| Pages: |
e45076 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Miyake T |
| Year: |
2014 |
| Journal: |
Biochem Biophys Res Commun |
| Title: |
TRPM2 contributes to LPS/IFN?-induced production of nitric oxide via the p38/JNK pathway in microglia. |
| Volume: |
444 |
| Issue: |
2 |
| Pages: |
212-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Xu J |
| Year: |
2012 |
| Journal: |
J Biol Chem |
| Title: |
Striatal-enriched protein-tyrosine phosphatase (STEP) regulates Pyk2 kinase activity. |
| Volume: |
287 |
| Issue: |
25 |
| Pages: |
20942-56 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Revuelta-L?pez E |
| Year: |
2015 |
| Journal: |
J Mol Cell Cardiol |
| Title: |
Hypoxia-driven sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (SERCA2) downregulation depends on low-density lipoprotein receptor-related protein 1 (LRP1)-signalling in cardiomyocytes. |
| Volume: |
85 |
|
| Pages: |
25-36 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sanger JM |
| Year: |
2010 |
| Journal: |
Cytoskeleton (Hoboken) |
| Title: |
Arg/Abl-binding protein, a Z-body and Z-band protein, binds sarcomeric, costameric, and signaling molecules. |
| Volume: |
67 |
| Issue: |
12 |
| Pages: |
808-23 |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1379
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
728
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
187
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhang J |
| Year: |
2010 |
| Journal: |
Hum Mol Genet |
| Title: |
Polycystic kidney disease protein fibrocystin localizes to the mitotic spindle and regulates spindle bipolarity. |
| Volume: |
19 |
| Issue: |
17 |
| Pages: |
3306-19 |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Family |
| Description: |
This family of proteins is involved in promoting ciliogenesis within renal epithelial cells, contributing to the formation of kidney tubules and maintaining the lumen architecture [, ]. They play a role in cellular symmetry, ensuring proper bipolar cell division by regulating centrosome duplication and mitotic spindle assembly []. These proteins also maintain oriented cell division during tubular elongation via the planar cell polarity pathway. They are involved in epithelial cell morphogenesis, regulating cell-cell and cell-matrix adhesion, and participating in cell motility. They enhance cell-cell contact by positively regulating PTK2 kinase activity, which can lead to increased epithelial cell proliferation through HRAS/RAF1 pathways or decreased apoptosis via the PDK1/AKT1 pathway []. Additionally, they may have roles in collecting-duct and biliary differentiation, as well as in the proliferation of cholangiocytes and the production of CCN2 in a CXCL8-dependent manner []. |
|
•
•
•
•
•
|
| Publication |
| First Author: |
B?ttger V |
| Year: |
1995 |
| Journal: |
Eur J Biochem |
| Title: |
Epitope mapping of monoclonal antibodies to keratin 19 using keratin fragments, synthetic peptides and phage peptide libraries. |
| Volume: |
231 |
| Issue: |
2 |
| Pages: |
475-85 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Malgaretti N |
| Year: |
1997 |
| Journal: |
J Biol Chem |
| Title: |
Mmot1, a new helix-loop-helix transcription factor gene displaying a sharp expression boundary in the embryonic mouse brain. |
| Volume: |
272 |
| Issue: |
28 |
| Pages: |
17632-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Carothers AM |
| Year: |
2006 |
| Journal: |
Exp Cell Res |
| Title: |
Deficient E-cadherin adhesion in C57BL/6J-Min/+ mice is associated with increased tyrosine kinase activity and RhoA-dependent actomyosin contractility. |
| Volume: |
312 |
| Issue: |
4 |
| Pages: |
387-400 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bjarnadottir M |
| Year: |
2007 |
| Journal: |
J Neurosci |
| Title: |
Neuregulin1 (NRG1) signaling through Fyn modulates NMDA receptor phosphorylation: differential synaptic function in NRG1+/- knock-outs compared with wild-type mice. |
| Volume: |
27 |
| Issue: |
17 |
| Pages: |
4519-29 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Epple H |
| Year: |
2008 |
| Journal: |
Mol Cell Biol |
| Title: |
Phospholipase Cgamma2 modulates integrin signaling in the osteoclast by affecting the localization and activation of Src kinase. |
| Volume: |
28 |
| Issue: |
11 |
| Pages: |
3610-22 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Iskander SM |
| Year: |
2018 |
| Journal: |
J Am Soc Nephrol |
| Title: |
Protein Kinase 2? Is Expressed in Neural Crest-Derived Urinary Pacemaker Cells and Required for Pyeloureteric Contraction. |
| Volume: |
29 |
| Issue: |
4 |
| Pages: |
1198-1209 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yamamoto S |
| Year: |
2008 |
| Journal: |
Nat Med |
| Title: |
TRPM2-mediated Ca2+influx induces chemokine production in monocytes that aggravates inflammatory neutrophil infiltration. |
| Volume: |
14 |
| Issue: |
7 |
| Pages: |
738-47 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Le HT |
| Year: |
2006 |
| Journal: |
J Neurochem |
| Title: |
Reduced NMDA receptor tyrosine phosphorylation in PTPalpha-deficient mouse synaptosomes is accompanied by inhibition of four src family kinases and Pyk2: an upstream role for PTPalpha in NMDA receptor regulation. |
| Volume: |
98 |
| Issue: |
6 |
| Pages: |
1798-809 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Pierau M |
| Year: |
2009 |
| Journal: |
J Immunol |
| Title: |
Protein kinase B/Akt signals impair Th17 differentiation and support natural regulatory T cell function and induced regulatory T cell formation. |
| Volume: |
183 |
| Issue: |
10 |
| Pages: |
6124-34 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yoshida K |
| Year: |
2000 |
| Journal: |
J Biol Chem |
| Title: |
Mediation by the protein-tyrosine kinase Tec of signaling between the B cell antigen receptor and Dok-1. |
| Volume: |
275 |
| Issue: |
32 |
| Pages: |
24945-52 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ando-Akatsuka Y |
| Year: |
1996 |
| Journal: |
J Cell Biol |
| Title: |
Interspecies diversity of the occludin sequence: cDNA cloning of human, mouse, dog, and rat-kangaroo homologues. |
| Volume: |
133 |
| Issue: |
1 |
| Pages: |
43-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gueth-Hallonet C |
| Year: |
1993 |
| Journal: |
J Cell Sci |
| Title: |
gamma-Tubulin is present in acentriolar MTOCs during early mouse development. |
| Volume: |
105 ( Pt 1) |
|
| Pages: |
157-66 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kim I |
| Year: |
2008 |
| Journal: |
J Am Soc Nephrol |
| Title: |
Fibrocystin/polyductin modulates renal tubular formation by regulating polycystin-2 expression and function. |
| Volume: |
19 |
| Issue: |
3 |
| Pages: |
455-68 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hu B |
| Year: |
2011 |
| Journal: |
Exp Cell Res |
| Title: |
Cystogenesis in ARPKD results from increased apoptosis in collecting duct epithelial cells of Pkhd1 mutant kidneys. |
| Volume: |
317 |
| Issue: |
2 |
| Pages: |
173-87 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tsunoda T |
| Year: |
2019 |
| Journal: |
J Hepatol |
| Title: |
Loss of fibrocystin promotes interleukin-8-dependent proliferation and CTGF production of biliary epithelium. |
| Volume: |
71 |
| Issue: |
1 |
| Pages: |
143-152 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Porter RM |
| Year: |
1998 |
| Journal: |
J Biol Chem |
| Title: |
cDNA cloning, expression, and assembly characteristics of mouse keratin 16. |
| Volume: |
273 |
| Issue: |
48 |
| Pages: |
32265-72 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Rothbarth K |
| Year: |
1993 |
| Journal: |
J Cell Sci |
| Title: |
cDNA-derived molecular characteristics and antibodies to a new centrosome-associated and G2/M phase-prevalent protein. |
| Volume: |
104 ( Pt 1) |
|
| Pages: |
19-30 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Smith FJ |
| Year: |
2002 |
| Journal: |
Biochem Biophys Res Commun |
| Title: |
Cloning of human, murine, and marsupial keratin 7 and a survey of K7 expression in the mouse. |
| Volume: |
297 |
| Issue: |
4 |
| Pages: |
818-27 |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
798
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
2477
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1052
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Masuhara M |
| Year: |
2000 |
| Journal: |
Biochem Biophys Res Commun |
| Title: |
Molecular cloning of murine STAP-1, the stem-cell-specific adaptor protein containing PH and SH2 domains. |
| Volume: |
268 |
| Issue: |
3 |
| Pages: |
697-703 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mrowiec K |
| Year: |
2021 |
| Journal: |
Biochim Biophys Acta Mol Cell Res |
| Title: |
The periphilin 1-like BFAR isoform 3 is highly expressed in transcriptionally silent oocytes and involved in RNA metabolism. |
| Volume: |
1868 |
| Issue: |
10 |
| Pages: |
119086 |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
535
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wajapeyee N |
| Year: |
2013 |
| Journal: |
Genes Dev |
| Title: |
Oncogenic RAS directs silencing of tumor suppressor genes through ordered recruitment of transcriptional repressors. |
| Volume: |
27 |
| Issue: |
20 |
| Pages: |
2221-6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Papanicolaou KN |
| Year: |
2012 |
| Journal: |
Circ Res |
| Title: |
Mitofusins 1 and 2 are essential for postnatal metabolic remodeling in heart. |
| Volume: |
111 |
| Issue: |
8 |
| Pages: |
1012-26 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
151
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jung H |
| Year: |
2018 |
| Journal: |
Nat Neurosci |
| Title: |
Sexually dimorphic behavior, neuronal activity, and gene expression in Chd8-mutant mice. |
| Volume: |
21 |
| Issue: |
9 |
| Pages: |
1218-1228 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Del Mar Masdeu M |
| Year: |
2017 |
| Journal: |
Oncotarget |
| Title: |
Identification of novel Ack1-interacting proteins and Ack1 phosphorylated sites in mouse brain by mass spectrometry. |
| Volume: |
8 |
| Issue: |
60 |
| Pages: |
101146-101157 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
4059
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
4060
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
4059
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Husi H |
| Year: |
2000 |
| Journal: |
Nat Neurosci |
| Title: |
Proteomic analysis of NMDA receptor-adhesion protein signaling complexes. |
| Volume: |
3 |
| Issue: |
7 |
| Pages: |
661-9 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
4249
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
4249
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
4247
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mammalian Functional Genomics Centre |
| Year: |
2010 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Alleles produced for the NorCOMM project by the Mammalian Functional Genomics Centre (Mfgc), University of Manitoba |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
The Jackson Laboratory |
| Year: |
2005 |
| Journal: |
Unpublished |
| Title: |
Information obtained from The Jackson Laboratory, Bar Harbor, ME |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
MGI and IMPC |
| Year: |
2017 |
| Journal: |
MGI Direct Data Submission |
| Title: |
MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC) |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Friedel RH |
| Year: |
2007 |
| Journal: |
Brief Funct Genomic Proteomic |
| Title: |
EUCOMM--the European conditional mouse mutagenesis program. |
| Volume: |
6 |
| Issue: |
3 |
| Pages: |
180-5 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
MGI and IMPC |
| Year: |
2018 |
| Journal: |
Database Release |
| Title: |
MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC) |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
MGI and IMPC |
| Year: |
2026 |
| Journal: |
Database Release |
| Title: |
MGI Load of Molecular Notes for Endonuclease-Mediated (CRISPR) Alleles from the International Mouse Phenotyping Consortium (IMPC) |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2003 |
|
| Title: |
Data Curation Using Mouse Genome Assembly |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lennon G |
| Year: |
1999 |
| Journal: |
Database Download |
| Title: |
WashU-HHMI Mouse EST Project |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Carninci P |
| Year: |
2005 |
| Journal: |
Science |
| Title: |
The transcriptional landscape of the mammalian genome. |
| Volume: |
309 |
| Issue: |
5740 |
| Pages: |
1559-63 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
GOA curators |
| Year: |
2016 |
|
| Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
|
|
|
|
•
•
•
•
•
|