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Search results 1601 to 1700 out of 3113 for Rac1

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Type Details Score
Publication
29432743 | J:273430
First Author: Kou W
Year: 2018
Journal: Biochem Biophys Res Commun
Title: The inhibition of the effect and mechanism of vascular intimal hyperplasia in Tiam1 knockout mice.
Volume: 497
Issue: 1
Pages: 248-255
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Publication
37146610 | J:338035
First Author: Li L
Year: 2023
Journal: Neuron
Title: Tiam1 coordinates synaptic structural and functional plasticity underpinning the pathophysiology of neuropathic pain.
Volume: 111
Issue: 13
Pages: 2038-2050.e6
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Protein Coding Gene
MGI:1923385 | Prex2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:106913 | Abi2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:109605 | Srgap2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:87860 | Abl2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1890563 | Wasf1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1344426 | Esyt1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1917172 | Vrk2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2149010 | Dock2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1924134 | Cyfip2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:3045246 | Arhgef15
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:892877 | Pld2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1927140 | Git1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2137336 | Baiap2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2178103 | Arhgdia
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1332637 | Arhgap5
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:97384 | Ntrk2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1890169 | Erbin
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1927222 | Diaph3
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:107858 | Arhgap39
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1918552 | Arhgap26
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1918685 | Arhgap21
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:104913 | Abi1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1355333 | Nckap1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2445003 | Arhgap1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:88145 | Bdnf
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1095416 | Jag1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:95281 | Ect2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:109585 | Pld1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:3036286 | Arhgef39
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1914549 | Dock7
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1098641 | Wasf2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1925912 | Arhgef19
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:95278 | Epha2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2658986 | Wasf3
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1915406 | Brk1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:105305 | Slc1a5
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2141874 | Plekhg2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1917834 | Pak4
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1916960 | Arap1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2444453 | Arhgef10
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:108022 | Pkn1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2450166 | Arhgap32
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1933966 | Mcam
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2429763 | Dock3
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2151070 | Ophn1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q80TH2
Organism: Mus musculus/domesticus
Length: 1402  
Fragment?: false
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Protein
Q3U7R1
Organism: Mus musculus/domesticus
Length: 1092  
Fragment?: false
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Protein
P51912
Organism: Mus musculus/domesticus
Length: 553  
Fragment?: false
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Protein
P21237
Organism: Mus musculus/domesticus
Length: 249  
Fragment?: false
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Protein
Q68FF6
Organism: Mus musculus/domesticus
Length: 770  
Fragment?: false
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Protein
Q66JY6
Organism: Mus musculus/domesticus
Length: 344  
Fragment?: false
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Protein
Q9Z207
Organism: Mus musculus/domesticus
Length: 1171  
Fragment?: false
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Protein
P62484
Organism: Mus musculus/domesticus
Length: 446  
Fragment?: false
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Protein
Q4LDD4
Organism: Mus musculus/domesticus
Length: 1452  
Fragment?: false
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Protein
Q99J31
Organism: Mus musculus/domesticus
Length: 802  
Fragment?: false
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Protein
Q8BTW9
Organism: Mus musculus/domesticus
Length: 593  
Fragment?: false
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Protein
Q4JIM5
Organism: Mus musculus/domesticus
Length: 1182  
Fragment?: false
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Protein
Q8CBW3
Organism: Mus musculus/domesticus
Length: 481  
Fragment?: false
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Protein
Q8C033
Organism: Mus musculus/domesticus
Length: 1345  
Fragment?: false
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Protein
Q5FWH6
Organism: Mus musculus/domesticus
Length: 849  
Fragment?: false
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Protein
Q8BWA8
Organism: Mus musculus/domesticus
Length: 802  
Fragment?: false
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Protein
Q99PT1
Organism: Mus musculus/domesticus
Length: 204  
Fragment?: false
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Protein
Q91VR8
Organism: Mus musculus/domesticus
Length: 75  
Fragment?: false
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Protein
Q9QXX0
Organism: Mus musculus/domesticus
Length: 1218  
Fragment?: false
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Protein
P70268
Organism: Mus musculus/domesticus
Length: 946  
Fragment?: false
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Protein
Q8R2Y2
Organism: Mus musculus/domesticus
Length: 648  
Fragment?: false
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Protein
Q03145
Organism: Mus musculus/domesticus
Length: 977  
Fragment?: false
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Protein
Q5FWK3
Organism: Mus musculus/domesticus
Length: 439  
Fragment?: false
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Protein
P97393
Organism: Mus musculus/domesticus
Length: 1501  
Fragment?: false
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Protein
Q6ZQ82
Organism: Mus musculus/domesticus
Length: 814  
Fragment?: false
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Protein
Q6DFV3
Organism: Mus musculus/domesticus
Length: 1944  
Fragment?: false
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Protein
Q6KAU7
Organism: Mus musculus/domesticus
Length: 1340  
Fragment?: false
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Protein
P15209
Organism: Mus musculus/domesticus
Length: 821  
Fragment?: false
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Protein
Q811P8
Organism: Mus musculus/domesticus
Length: 2089  
Fragment?: false
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Protein
P59281
Organism: Mus musculus/domesticus
Length: 1107  
Fragment?: false
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Protein
P97813
Organism: Mus musculus/domesticus
Length: 933  
Fragment?: false
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Protein
Q8BN21
Organism: Mus musculus/domesticus
Length: 503  
Fragment?: false
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Protein
Q91Z67
Organism: Mus musculus/domesticus
Length: 1071  
Fragment?: false
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Protein
Q9Z280
Organism: Mus musculus/domesticus
Length: 1074  
Fragment?: false
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Protein
Q8R5H6
Organism: Mus musculus/domesticus
Length: 559  
Fragment?: false
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Protein
Q8BH43
Organism: Mus musculus/domesticus
Length: 497  
Fragment?: false
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Protein
Q8VHI6
Organism: Mus musculus/domesticus
Length: 501  
Fragment?: false
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Publication
15304343 | -
First Author: Donald S
Year: 2004
Journal: FEBS Lett
Title: P-Rex2, a new guanine-nucleotide exchange factor for Rac.
Volume: 572
Issue: 1-3
Pages: 172-6
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Protein
A2AWQ2
Organism: Mus musculus/domesticus
Length: 170  
Fragment?: true
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Publication
12919680 | -
First Author: Mollinari C
Year: 2003
Journal: Dev Cell
Title: The mammalian passenger protein TD-60 is an RCC1 family member with an essential role in prometaphase to metaphase progression.
Volume: 5
Issue: 2
Pages: 295-307
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Publication
16568096 | -
First Author: Prieto-Sánchez RM
Year: 2006
Journal: Oncogene
Title: Involvement of the Rho/Rac family member RhoG in caveolar endocytosis.
Volume: 25
Issue: 21
Pages: 2961-73
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Protein Domain
IPR028641 | RCC2
Type: Family
Description: Protein RCC2 (also known as TD-60) interacts with microtubules and is required for completion of mitosis and cytokinesis []. It may function as a guanine nucleotide exchange factor for the small GTPase RAC1 [].This entry also includes some uncharacterised bacterial proteins.
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Protein Domain
IPR041852 | ARHGAP6_RhoGAP
Type: Domain
Description: This entry represent the RhoGAP domain found in ARHGAP6 and ARHGAP36.Rho GTPase activating protein 6 (ARHGAP6/RHOGAP6) shows GAP activity towards RhoA, but not towards Cdc42 and Rac1 []. ARHGAP6 is often deleted in microphthalmia with linear skin defects syndrome (MLS); MLS is a severe X-linked developmental disorder []. ARHGAP36 is a potent antagonist of PKAsignalling [].
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Protein Domain
IPR037367 | Rex2_DEP_1
Type: Domain
Description: PREX2 functions as a RAC1 guanine nucleotide exchange factor (GEF), activating Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein []. It contains an N-terminal RhoGEF domain, two DEP and PDZ domains.This entry represents the first DEP domain of PREX2.
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Protein Domain
IPR037863 | RHOGAP6/36
Type: Family
Description: Rho GTPase activating protein 6 (ArhGAP6/RHOGAP6) shows GAP activity towards RhoA, but not towards Cdc42 and Rac1 []. ArhGAP6 is often deleted in microphthalmia with linear skin defects syndrome (MLS); MLS is a severe X-linked developmental disorder [].This family also includes ARHGAP36, which is a potent antagonist of PKA signalling [].
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Protein Domain
IPR042734 | RhoG
Type: Family
Description: RhoG is a GTPase with high sequence similarity to members of the Rac subfamily, including the regions involved in effector recognition and binding. However, RhoG does not bind to known Rac1 and Cdc42 effectors, including proteins containing a Cdc42/Rac interacting binding (CRIB) motif. Instead, RhoG interacts directly with Elmo, an upstream regulator of Rac1, in a GTP-dependent manner and forms a ternary complex with Dock180 to induce activation of Rac1 []. The RhoG-Elmo-Dock180 pathway is required for activation of Rac1 and cell spreading mediated by integrin, as well as for neurite outgrowth induced by nerve growth factor. Thus RhoG activates Rac1 through Elmo and Dock180 to control cell morphology []. RhoG has also been shown to play a role in caveolar trafficking []and has a novel role in signaling the neutrophil respiratory burst stimulated by G protein-coupled receptor (GPCR) agonists []. Most Rho proteins contain a lipid modification site at the C terminus, with a typical sequence motif CaaX, where a = an aliphatic amino acid and X = any amino acid. Lipid binding is essential for membrane attachment, a key feature of most Rho proteins.
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Publication
11707441 | J:73960
First Author: Matsuo N
Year: 2002
Journal: J Biol Chem
Title: Characterization of STEF, a guanine nucleotide exchange factor for Rac1, required for neurite growth.
Volume: 277
Issue: 4
Pages: 2860-8
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Protein
A2CG49
Organism: Mus musculus/domesticus
Length: 2964  
Fragment?: false
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Protein
Q9ES28
Organism: Mus musculus/domesticus
Length: 862  
Fragment?: false
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HT Experiment
GSE72184 | Next generation sequencing analysis of DN1 transcriptomes from Wild type, gl/gl and transgenic CD2-Ostm1 gl/gl mice
Series Id: E-GEOD-72184
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Protein
Q8K4I3
Organism: Mus musculus/domesticus
Length: 771  
Fragment?: false
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Publication
16330714 | J:104526
First Author: Hamelers IH
Year: 2005
Journal: J Cell Biol
Title: The Rac activator Tiam1 is required for (alpha)3(beta)1-mediated laminin-5 deposition, cell spreading, and cell migration.
Volume: 171
Issue: 5
Pages: 871-81
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Publication
18592271 | J:142164
First Author: Strumane K
Year: 2009
Journal: J Cancer Res Clin Oncol
Title: Tiam1-deficiency impairs mammary tumor formation in MMTV-c-neu but not in MMTV-c-myc mice.
Volume: 135
Issue: 1
Pages: 69-80
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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Cambridge CB2 3EH, United Kingdom