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Search results 1601 to 1700 out of 2424 for Ran

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Type Details Score
Allele
Name: RAN GTPase activating protein 1; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Allele
Name: RAN binding protein 2; targeted mutation 1, Shanghai Model Organisms Center
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
Allele
Name: RAN binding protein 1; targeted mutation 1c, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Conditional ready
Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
Genotype
Symbol: Ranbp9/Ranbp9
Background: B6.129P2-Ranbp9
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Ranbp2/Ranbp2
Background: either: 129P2/OlaHsd-Ranbp2 or (involves: 129P2/OlaHsd * C57BL/6J)
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Ranbp1/Ranbp1
Background: involves: 129S2/SvPas * C57BL/6
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Ranbp10/Ranbp10
Background: either: (involves: 129P2/OlaHsd) or (involves: 129P2/OlaHsd * C57BL/6)
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Ranbp9/Ranbp9
Background: Not Specified
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Ranbp2/Ranbp2
Background: C57BL/6N-Ranbp2/MbpMmucd
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Ranbp1/Ranbp1
Background: B6.129S4(129S6)-Ranbp1
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Rangrf/Rangrf
Background: involves: C57BL/6
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Ranbp10/Ranbp10
Background: C57BL/6N-Ranbp10/Ucd
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Ranbp3/Ranbp3
Background: C57BL/6NJ-Ranbp3/Mmjax
Zygosity: hm
Has Mutant Allele: true
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Uchimura Y
Year: 2004
Journal: FEBS Lett
Title: Generation of SUMO-1 modified proteins in E. coli: towards understanding the biochemistry/structural biology of the SUMO-1 pathway.
Volume: 564
Issue: 1-2
Pages: 85-90
GXD Expression  
Probe: MGI:1330766
Assay Type: Immunohistochemistry
Annotation Date: 2024-11-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1698917
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:7764914
Age: embryonic day 10.5
Note: The ramus dorsalis turned dorsolaterally and formed muscle branches to the dorsal muscle groups and skin sensory rami in a highly segmental pattern. The rami ventralis ran ventrally and sprouted the lateral cutaneous branches toward the lateral body wall.
Specimen Label: 3E
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:5617712
Assay Type: RNA in situ
Annotation Date: 2015-03-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3596116
Pattern: Regionally restricted
Stage: TS16
Assay Id: MGI:5617724
Age: embryonic day 10.0
Note: Expression is in cells that formed wide streams from the lateral dermomyotome to the limb bud and in a stream that originated from the occipital somites that ran anteriorly.
Specimen Label: 3D
Detected: true
Specimen Num: 9
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2019-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1683927
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:6273325
Age: postnatal day 0
Note: Expressed in the epithelial component of the juxta-oral organ. The middle portion ran parallel to the anterior surface of the mandible and went beneath the parotid duct and then the zygomatic arch before reaching the orbit.
Specimen Label: 3H
Detected: true
Specimen Num: 18
Publication
First Author: Chen C
Year: 2005
Journal: Oncogene
Title: Ubiquitin-proteasome degradation of KLF5 transcription factor in cancer and untransformed epithelial cells.
Volume: 24
Issue: 20
Pages: 3319-27
Publication
First Author: Nie Y
Year: 2017
Journal: PLoS Pathog
Title: GPATCH3 negatively regulates RLR-mediated innate antiviral responses by disrupting the assembly of VISA signalosome.
Volume: 13
Issue: 4
Pages: e1006328
Publication
First Author: Bose HS
Year: 2008
Journal: Biochemistry
Title: StAR-like activity and molten globule behavior of StARD6, a male germ-line protein.
Volume: 47
Issue: 8
Pages: 2277-88
Publication
First Author: Wilkison M
Year: 2012
Journal: Am J Pathol
Title: Type 1 interferons suppress accelerated osteoclastogenesis and prevent loss of bone mass during systemic inflammatory responses to Pneumocystis lung infection.
Volume: 181
Issue: 1
Pages: 151-62
Publication  
First Author: Chen K
Year: 2017
Journal: Brain Behav Immun
Title: Toll-interacting protein deficiency promotes neurodegeneration via impeding autophagy completion in high-fat diet-fed ApoE-/- mouse model.
Volume: 59
Pages: 200-210
Publication
First Author: Foks AC
Year: 2013
Journal: PLoS One
Title: Agonistic anti-TIGIT treatment inhibits T cell responses in LDLr deficient mice without affecting atherosclerotic lesion development.
Volume: 8
Issue: 12
Pages: e83134
Publication
First Author: Zhang S
Year: 2019
Journal: Nat Commun
Title: Both fallopian tube and ovarian surface epithelium are cells-of-origin for high-grade serous ovarian carcinoma.
Volume: 10
Issue: 1
Pages: 5367
Publication
First Author: Sun Y
Year: 2007
Journal: Hum Mol Genet
Title: Combined saposin C and D deficiencies in mice lead to a neuronopathic phenotype, glucosylceramide and alpha-hydroxy ceramide accumulation, and altered prosaposin trafficking.
Volume: 16
Issue: 8
Pages: 957-71
Publication
First Author: Xu YH
Year: 2011
Journal: Mol Genet Metab
Title: Accumulation and distribution of α-synuclein and ubiquitin in the CNS of Gaucher disease mouse models.
Volume: 102
Issue: 4
Pages: 436-47
Publication
First Author: Dhillon JS
Year: 2017
Journal: PLoS One
Title: A novel panel of α-synuclein antibodies reveal distinctive staining profiles in synucleinopathies.
Volume: 12
Issue: 9
Pages: e0184731
Publication
First Author: Tang X
Year: 2015
Journal: Biol Reprod
Title: Systemic morphine treatment derails normal uterine receptivity, leading to embryo implantation failure in mice.
Volume: 92
Issue: 5
Pages: 118
Publication  
First Author: Xu G
Year: 2015
Journal: Acta Neuropathol Commun
Title: Murine Aβ over-production produces diffuse and compact Alzheimer-type amyloid deposits.
Volume: 3
Pages: 72
Publication
First Author: Volk-Draper L
Year: 2024
Journal: PLoS One
Title: Tumor microenvironment restricts IL-10 induced multipotent progenitors to myeloid-lymphatic phenotype.
Volume: 19
Issue: 4
Pages: e0298465
Publication
First Author: Chen L
Year: 2021
Journal: Sci Rep
Title: Overexpression of ferroptosis defense enzyme Gpx4 retards motor neuron disease of SOD1G93A mice.
Volume: 11
Issue: 1
Pages: 12890
Publication
First Author: Croft CL
Year: 2018
Journal: PLoS One
Title: Novel monoclonal antibodies targeting the microtubule-binding domain of human tau.
Volume: 13
Issue: 4
Pages: e0195211
Publication
First Author: Liang H
Year: 2009
Journal: J Biol Chem
Title: Short form glutathione peroxidase 4 is the essential isoform required for survival and somatic mitochondrial functions.
Volume: 284
Issue: 45
Pages: 30836-44
Publication  
First Author: Huang D
Year: 2021
Journal: Front Immunol
Title: IL-27 Mediates Pro-Inflammatory Effects via the ERK Signaling Pathway During Preterm Labor.
Volume: 12
Pages: 709229
Publication
First Author: Murad JM
Year: 2010
Journal: J Biol Chem
Title: Inhibitor of DNA binding 4 (ID4) regulation of adipocyte differentiation and adipose tissue formation in mice.
Volume: 285
Issue: 31
Pages: 24164-73
Publication
First Author: Fernandez E
Year: 2006
Journal: Alcohol Clin Exp Res
Title: Monoamine metabolism and behavioral responses to ethanol in mitochondrial aldehyde dehydrogenase knockout mice.
Volume: 30
Issue: 10
Pages: 1650-8
Publication
First Author: Szatko KP
Year: 2020
Journal: Nat Commun
Title: Neural circuits in the mouse retina support color vision in the upper visual field.
Volume: 11
Issue: 1
Pages: 3481
Publication
First Author: Yang Y
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: CYLD regulates spindle orientation by stabilizing astral microtubules and promoting dishevelled-NuMA-dynein/dynactin complex formation.
Volume: 111
Issue: 6
Pages: 2158-63
Publication  
First Author: Chen L
Year: 2022
Journal: Free Radic Biol Med
Title: Enhanced defense against ferroptosis ameliorates cognitive impairment and reduces neurodegeneration in 5xFAD mice.
Volume: 180
Pages: 1-12
Publication
First Author: Zhang L
Year: 2009
Journal: Am J Pathol
Title: Chemokine CXCL16 regulates neutrophil and macrophage infiltration into injured muscle, promoting muscle regeneration.
Volume: 175
Issue: 6
Pages: 2518-27
Publication
First Author: Liu X
Year: 2023
Journal: FASEB J
Title: Indispensable role of Nectin-like 4 in regulating synapse-related molecules, synaptic structure, and individual behavior.
Volume: 37
Issue: 6
Pages: e22970
Publication
First Author: Juan F
Year: 2008
Journal: Int J Cardiol
Title: The changes of the cardiac structure and function in cTnTR141W transgenic mice.
Volume: 128
Issue: 1
Pages: 83-90
Publication
First Author: Liang H
Year: 2007
Journal: Biochem Biophys Res Commun
Title: Gpx4 protects mitochondrial ATP generation against oxidative damage.
Volume: 356
Issue: 4
Pages: 893-8
Publication
First Author: Koulajian K
Year: 2013
Journal: Am J Physiol Endocrinol Metab
Title: Overexpression of glutathione peroxidase 4 prevents β-cell dysfunction induced by prolonged elevation of lipids in vivo.
Volume: 305
Issue: 2
Pages: E254-62
Publication
First Author: Pierce A
Year: 2010
Journal: Biochem Biophys Res Commun
Title: A Novel mouse model of enhanced proteostasis: Full-length human heat shock factor 1 transgenic mice.
Volume: 402
Issue: 1
Pages: 59-65
Publication
First Author: Xiong MG
Year: 2020
Journal: EMBO Rep
Title: RNF152 positively regulates TLR/IL-1R signaling by enhancing MyD88 oligomerization.
Volume: 21
Issue: 3
Pages: e48860
Publication
First Author: Gu J
Year: 2013
Journal: Int J Clin Exp Pathol
Title: Mouse p63 variants and chondrogenesis.
Volume: 6
Issue: 12
Pages: 2872-9
Publication
First Author: Hao W
Year: 2013
Journal: J Biol Chem
Title: Structural basis for the interaction between the potato virus X resistance protein (Rx) and its cofactor Ran GTPase-activating protein 2 (RanGAP2).
Volume: 288
Issue: 50
Pages: 35868-76
Protein
Organism: Mus musculus/domesticus
Length: 620  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 653  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 648  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 710  
Fragment?: false
Publication
First Author: Subramanian M
Year: 2014
Journal: J Clin Invest
Title: An AXL/LRP-1/RANBP9 complex mediates DC efferocytosis and antigen cross-presentation in vivo.
Volume: 124
Issue: 3
Pages: 1296-308
Publication
First Author: Um JW
Year: 2006
Journal: J Biol Chem
Title: Parkin ubiquitinates and promotes the degradation of RanBP2.
Volume: 281
Issue: 6
Pages: 3595-603
Publication
First Author: Menon RP
Year: 2004
Journal: J Mol Biol
Title: The C terminus of fragile X mental retardation protein interacts with the multi-domain Ran-binding protein in the microtubule-organising centre.
Volume: 343
Issue: 1
Pages: 43-53
Publication
First Author: Di Matteo G
Year: 1998
Journal: J Biol Chem
Title: Interactions with single-stranded and double-stranded DNA-binding factors and alternative promoter conformation upon transcriptional activation of the Htf9-a/RanBP1 and Htf9-c genes.
Volume: 273
Issue: 1
Pages: 495-505
Publication
First Author: Chen F
Year: 2015
Journal: Mol Cell Biol
Title: Nuclear Export of Smads by RanBP3L Regulates Bone Morphogenetic Protein Signaling and Mesenchymal Stem Cell Differentiation.
Volume: 35
Issue: 10
Pages: 1700-11
Publication
First Author: Lavia P
Year: 1987
Journal: EMBO J
Title: Coincident start sites for divergent transcripts at a randomly selected CpG-rich island of mouse.
Volume: 6
Issue: 9
Pages: 2773-9
Publication
First Author: Bird A
Year: 1985
Journal: Cell
Title: A fraction of the mouse genome that is derived from islands of nonmethylated, CpG-rich DNA.
Volume: 40
Issue: 1
Pages: 91-9
Publication
First Author: Wang D
Year: 2002
Journal: J Biol Chem
Title: Activation of Ras/Erk pathway by a novel MET-interacting protein RanBPM.
Volume: 277
Issue: 39
Pages: 36216-22
Publication
First Author: Seebahn A
Year: 2008
Journal: FEBS Lett
Title: RanBPM is expressed in synaptic layers of the mammalian retina and binds to metabotropic glutamate receptors.
Volume: 582
Issue: 16
Pages: 2453-7
Publication
First Author: Saitoh N
Year: 2012
Journal: Mol Biol Cell
Title: The distribution of phosphorylated SR proteins and alternative splicing are regulated by RANBP2.
Volume: 23
Issue: 6
Pages: 1115-28
Publication
First Author: Wang H
Year: 2013
Journal: J Biol Chem
Title: COPS5 (Jab1) protein increases β site processing of amyloid precursor protein and amyloid β peptide generation by stabilizing RanBP9 protein levels.
Volume: 288
Issue: 37
Pages: 26668-77
Publication
First Author: Liu H
Year: 2015
Journal: Mol Cell
Title: The Immune Adaptor SLP-76 Binds to SUMO-RANGAP1 at Nuclear Pore Complex Filaments to Regulate Nuclear Import of Transcription Factors in T Cells.
Volume: 59
Issue: 5
Pages: 840-9
Publication
First Author: Cortés-Montero E
Year: 2019
Journal: Antioxid Redox Signal
Title: The Axonal Motor Neuropathy-Related HINT1 Protein Is a Zinc- and Calmodulin-Regulated Cysteine SUMO Protease.
Volume: 31
Issue: 7
Pages: 503-520
Protein
Organism: Mus musculus/domesticus
Length: 3053  
Fragment?: false
Publication
First Author: Valencia A
Year: 1991
Journal: Biochemistry
Title: The ras protein family: evolutionary tree and role of conserved amino acids.
Volume: 30
Issue: 19
Pages: 4637-48
Publication
First Author: Pai EF
Year: 1990
Journal: EMBO J
Title: Refined crystal structure of the triphosphate conformation of H-ras p21 at 1.35 A resolution: implications for the mechanism of GTP hydrolysis.
Volume: 9
Issue: 8
Pages: 2351-9
Publication
First Author: Bourne HR
Year: 1990
Journal: Nature
Title: The GTPase superfamily: a conserved switch for diverse cell functions.
Volume: 348
Issue: 6297
Pages: 125-32
Publication  
First Author: Li H
Year: 2023
Journal: Biochem Biophys Res Commun
Title: GPX4 aggravates experimental autoimmune encephalomyelitis by inhibiting the functions of CD4(+) T cells.
Volume: 642
Pages: 57-65
Publication
First Author: Liddell JR
Year: 2024
Journal: Mol Neurodegener
Title: Microglial ferroptotic stress causes non-cell autonomous neuronal death.
Volume: 19
Issue: 1
Pages: 14
Strain
Attribute String: coisogenic, mutant strain, targeted mutation
Strain
Attribute String: coisogenic, mutant strain, targeted mutation
Strain
Attribute String: coisogenic, targeted mutation
Strain
Attribute String: coisogenic, targeted mutation
Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
Strain
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
Strain
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
Strain
Attribute String: targeted mutation, mutant stock
Genotype
Symbol: Ranbp2/Ranbp2<+>
Background: 129P2/OlaHsd-Ranbp2
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Ranbp2/Ranbp2<+>
Background: involves: 129P2/OlaHsd * C57BL/6J
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Rangap1/Rangap1
Background: involves: 129S2/SvPas * C57BL/6
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Ranbp2/Ranbp2
Background: involves: 129/Sv * C57BL/6
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Ranbp2/Ranbp2
Background: involves: 129/Sv * C57BL/6
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Ranbp9/Ranbp9 Tg(Amh-cre)8815Reb/?
Background: involves: 129 * C57BL/6J * FVB/N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Ranbp9/Ranbp9 Tg(Stra8-icre)1Reb/?
Background: involves: C57BL/6J * FVB/NJ
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Ranbp17/Ranbp17
Background: C57BL/6N-Ranbp17/Tcp
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Ranbp1/Ranbp1
Background: C57BL/6N-Ranbp1/Tcp
Zygosity: hm
Has Mutant Allele: true