| Type |
Details |
Score |
| GXD Expression |
| Probe: |
MGI:17850 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2024-05-01 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3705123 |
| Pattern: |
Not Specified |
| Stage: |
TS23 |
| Assay Id: |
MGI:7626258 |
| Age: |
embryonic day 15.5 |
| Image: |
4K |
|
| Specimen Label: |
4K |
| Detected: |
true |
| Specimen Num: |
11 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:17850 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2024-05-01 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3705123 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:7626258 |
| Age: |
embryonic day 15.5 |
| Image: |
4L |
| Note: |
Loss of expression in groups of motoneurons. |
| Specimen Label: |
4L |
| Detected: |
true |
| Specimen Num: |
12 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:17850 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2024-05-01 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3705121 |
| Pattern: |
Not Specified |
| Stage: |
TS21 |
| Assay Id: |
MGI:7626258 |
| Age: |
embryonic day 13.5 |
| Image: |
2J |
| Note: |
Expression in most motoneurons. |
| Specimen Label: |
2J |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7614999 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2024-03-22 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3826321 |
| Pattern: |
Not Specified |
| Stage: |
TS21 |
| Assay Id: |
MGI:7615006 |
| Age: |
embryonic day 13.5 |
|
| Note: |
Expression is in motoneurons. |
| Specimen Label: |
1A Brachial |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7614999 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2024-03-22 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3826321 |
| Pattern: |
Not Specified |
| Stage: |
TS21 |
| Assay Id: |
MGI:7615006 |
| Age: |
embryonic day 13.5 |
|
| Note: |
Expression is in motoneurons. |
| Specimen Label: |
1A Brachial section |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7614999 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2024-03-22 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3826321 |
| Pattern: |
Not Specified |
| Stage: |
TS21 |
| Assay Id: |
MGI:7615006 |
| Age: |
embryonic day 13.5 |
|
| Note: |
Expression is in motoneurons. |
| Specimen Label: |
2A |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:17850 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2024-05-01 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3826321 |
| Pattern: |
Widespread |
| Stage: |
TS21 |
| Assay Id: |
MGI:7626258 |
| Age: |
embryonic day 13.5 |
| Image: |
1B |
| Note: |
Expression in motoneurons in most motor columns. |
| Specimen Label: |
1B |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:17850 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2024-05-01 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3826321 |
| Pattern: |
Not Specified |
| Stage: |
TS21 |
| Assay Id: |
MGI:7626258 |
| Age: |
embryonic day 13.5 |
| Image: |
2A |
| Note: |
Expression in most motoneurons. |
| Specimen Label: |
2A |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:17850 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2024-05-01 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3826321 |
| Pattern: |
Not Specified |
| Stage: |
TS21 |
| Assay Id: |
MGI:7626258 |
| Age: |
embryonic day 13.5 |
| Image: |
2D |
| Note: |
Expression in most motoneurons. |
| Specimen Label: |
2D |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:17850 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2024-05-01 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3826323 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:7626258 |
| Age: |
embryonic day 15.5 |
| Image: |
4D |
| Note: |
Small decrease of expression in a group of motoneurons. |
| Specimen Label: |
4D |
| Detected: |
true |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:17850 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2024-05-01 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3826323 |
| Pattern: |
Not Specified |
| Stage: |
TS23 |
| Assay Id: |
MGI:7626258 |
| Age: |
embryonic day 15.5 |
| Image: |
4E |
|
| Specimen Label: |
4E |
| Detected: |
true |
| Specimen Num: |
8 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:17850 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2024-05-01 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3826323 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:7626258 |
| Age: |
embryonic day 15.5 |
| Image: |
4F |
| Note: |
Loss of expression in groups of motoneurons. |
| Specimen Label: |
4F |
| Detected: |
true |
| Specimen Num: |
9 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:17850 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2024-05-01 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3826323 |
| Pattern: |
Not Specified |
| Stage: |
TS23 |
| Assay Id: |
MGI:7626258 |
| Age: |
embryonic day 15.5 |
| Image: |
4M |
|
| Specimen Label: |
4M |
| Detected: |
true |
| Specimen Num: |
13 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:17850 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2024-05-01 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3826323 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:7626258 |
| Age: |
embryonic day 15.5 |
| Image: |
4N |
| Note: |
Loss of expression in a group of motoneurons. |
| Specimen Label: |
4N |
| Detected: |
true |
| Specimen Num: |
14 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:17850 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2025-01-10 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3826320 |
| Pattern: |
Not Specified |
| Stage: |
TS20 |
| Assay Id: |
MGI:7840365 |
| Age: |
embryonic day 12.5 |
| Image: |
6B |
|
| Specimen Label: |
6B |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhu S |
| Year: |
2015 |
| Journal: |
Nat Neurosci |
| Title: |
Identification of a Vav2-dependent mechanism for GDNF/Ret control of mesolimbic DAT trafficking. |
| Volume: |
18 |
| Issue: |
8 |
| Pages: |
1084-93 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Heanue TA |
| Year: |
2006 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Expression profiling the developing mammalian enteric nervous system identifies marker and candidate Hirschsprung disease genes. |
| Volume: |
103 |
| Issue: |
18 |
| Pages: |
6919-24 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Niu J |
| Year: |
2014 |
| Journal: |
PLoS One |
| Title: |
Dual innervation of neonatal Merkel cells in mouse touch domes. |
| Volume: |
9 |
| Issue: |
3 |
| Pages: |
e92027 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1115
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lindahl M |
| Year: |
2000 |
| Journal: |
Mol Cell Neurosci |
| Title: |
Expression and alternative splicing of mouse Gfra4 suggest roles in endocrine cell development. |
| Volume: |
15 |
| Issue: |
6 |
| Pages: |
522-33 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Vaquero M |
| Year: |
2019 |
| Journal: |
J Am Soc Nephrol |
| Title: |
Sprouty1 Controls Genitourinary Development via its N-Terminal Tyrosine. |
| Volume: |
30 |
| Issue: |
8 |
| Pages: |
1398-1411 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Montaño-Rodriguez AR |
| Year: |
2024 |
| Journal: |
Cells |
| Title: |
Striatal GDNF Neurons Chemoattract RET-Positive Dopamine Axons at Seven Times Farther Distance Than Medium Spiny Neurons. |
| Volume: |
13 |
| Issue: |
12 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Baaske MK |
| Year: |
2020 |
| Journal: |
Neurobiol Dis |
| Title: |
Parkin deficiency perturbs striatal circuit dynamics. |
| Volume: |
137 |
|
| Pages: |
104737 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chatterjee S |
| Year: |
2019 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Gene- and tissue-level interactions in normal gastrointestinal development and Hirschsprung disease. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Niu J |
| Year: |
2013 |
| Journal: |
J Neurosci |
| Title: |
Modality-based organization of ascending somatosensory axons in the direct dorsal column pathway. |
| Volume: |
33 |
| Issue: |
45 |
| Pages: |
17691-709 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wong A |
| Year: |
2005 |
| Journal: |
Mol Cell Biol |
| Title: |
Phosphotyrosine 1062 is critical for the in vivo activity of the Ret9 receptor tyrosine kinase isoform. |
| Volume: |
25 |
| Issue: |
21 |
| Pages: |
9661-73 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Iida M |
| Year: |
2020 |
| Journal: |
Aging Cell |
| Title: |
Hair graying with aging in mice carrying oncogenic RET. |
| Volume: |
19 |
| Issue: |
11 |
| Pages: |
e13273 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gao T |
| Year: |
2021 |
| Journal: |
JCI Insight |
| Title: |
Cell-autonomous retinoic acid receptor signaling has stage-specific effects on mouse enteric nervous system. |
| Volume: |
6 |
| Issue: |
10 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Brophy PD |
| Year: |
2001 |
| Journal: |
Development |
| Title: |
Regulation of ureteric bud outgrowth by Pax2-dependent activation of the glial derived neurotrophic factor gene. |
| Volume: |
128 |
| Issue: |
23 |
| Pages: |
4747-56 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kuure S |
| Year: |
2010 |
| Journal: |
Development |
| Title: |
The transcription factors Etv4 and Etv5 mediate formation of the ureteric bud tip domain during kidney development. |
| Volume: |
137 |
| Issue: |
12 |
| Pages: |
1975-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ohshima Y |
| Year: |
2010 |
| Journal: |
PLoS One |
| Title: |
c-RET molecule in malignant melanoma from oncogenic RET-carrying transgenic mice and human cell lines. |
| Volume: |
5 |
| Issue: |
4 |
| Pages: |
e10279 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Belkind-Gerson J |
| Year: |
2017 |
| Journal: |
Sci Rep |
| Title: |
Colitis promotes neuronal differentiation of Sox2+ and PLP1+ enteric cells. |
| Volume: |
7 |
| Issue: |
1 |
| Pages: |
2525 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Freem LJ |
| Year: |
2010 |
| Journal: |
J Anat |
| Title: |
The intrinsic innervation of the lung is derived from neural crest cells as shown by optical projection tomography in Wnt1-Cre;YFP reporter mice. |
| Volume: |
217 |
| Issue: |
6 |
| Pages: |
651-64 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Grimm J |
| Year: |
2001 |
| Journal: |
J Cell Biol |
| Title: |
Novel p62dok family members, dok-4 and dok-5, are substrates of the c-Ret receptor tyrosine kinase and mediate neuronal differentiation. |
| Volume: |
154 |
| Issue: |
2 |
| Pages: |
345-54 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Olson W |
| Year: |
2018 |
| Journal: |
J Comp Neurol |
| Title: |
Somatotopic organization of central arbors from nociceptive afferents develops independently of their intact peripheral target innervation. |
| Volume: |
526 |
| Issue: |
18 |
| Pages: |
3058-3065 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lemmetyinen TT |
| Year: |
2024 |
| Journal: |
iScience |
| Title: |
Mesenchymal GDNF promotes intestinal enterochromaffin cell differentiation. |
| Volume: |
27 |
| Issue: |
12 |
| Pages: |
111246 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Clarke JC |
| Year: |
2006 |
| Journal: |
Hum Mol Genet |
| Title: |
Regulation of c-Ret in the developing kidney is responsive to Pax2 gene dosage. |
| Volume: |
15 |
| Issue: |
23 |
| Pages: |
3420-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Batourina E |
| Year: |
2002 |
| Journal: |
Nat Genet |
| Title: |
Distal ureter morphogenesis depends on epithelial cell remodeling mediated by vitamin A and Ret. |
| Volume: |
32 |
| Issue: |
1 |
| Pages: |
109-15 |
|
•
•
•
•
•
|
| Author |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Amit M |
| Year: |
2019 |
| Journal: |
Int J Cancer |
| Title: |
RET, a targetable driver of pancreatic adenocarcinoma. |
| Volume: |
144 |
| Issue: |
12 |
| Pages: |
3014-3022 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Meka DP |
| Year: |
2015 |
| Journal: |
J Clin Invest |
| Title: |
Parkin cooperates with GDNF/RET signaling to prevent dopaminergic neuron degeneration. |
| Volume: |
125 |
| Issue: |
5 |
| Pages: |
1873-85 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ohno N |
| Year: |
2009 |
| Journal: |
Biochim Biophys Acta |
| Title: |
Dispensable role of protein 4.1B/DAL-1 in rodent adrenal medulla regarding generation of pheochromocytoma and plasmalemmal localization of TSLC1. |
| Volume: |
1793 |
| Issue: |
3 |
| Pages: |
506-15 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Anderson RB |
| Year: |
2006 |
| Journal: |
Cell Tissue Res |
| Title: |
Phenotypes of neural-crest-derived cells in vagal and sacral pathways. |
| Volume: |
323 |
| Issue: |
1 |
| Pages: |
11-25 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Huang T |
| Year: |
2013 |
| Journal: |
J Neurosci |
| Title: |
Tlx3 controls cholinergic transmitter and Peptide phenotypes in a subset of prenatal sympathetic neurons. |
| Volume: |
33 |
| Issue: |
26 |
| Pages: |
10667-75 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Roberts RR |
| Year: |
2008 |
| Journal: |
Am J Physiol Gastrointest Liver Physiol |
| Title: |
Disturbances of colonic motility in mouse models of Hirschsprung's disease. |
| Volume: |
294 |
| Issue: |
4 |
| Pages: |
G996-G1008 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cheng CC |
| Year: |
2018 |
| Journal: |
Elife |
| Title: |
Hair follicle epidermal stem cells define a niche for tactile sensation. |
| Volume: |
7 |
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Aron L |
| Year: |
2010 |
| Journal: |
PLoS Biol |
| Title: |
Pro-survival role for Parkinson's associated gene DJ-1 revealed in trophically impaired dopaminergic neurons. |
| Volume: |
8 |
| Issue: |
4 |
| Pages: |
e1000349 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Rothman TP |
| Year: |
1996 |
| Journal: |
Dev Biol |
| Title: |
Increased expression of laminin-1 and collagen (IV) subunits in the aganglionic bowel of ls/ls, but not c-ret -/- mice. |
| Volume: |
178 |
| Issue: |
2 |
| Pages: |
498-513 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Aubin J |
| Year: |
1999 |
| Journal: |
Am J Physiol |
| Title: |
Loss of Hoxa5 gene function in mice perturbs intestinal maturation. |
| Volume: |
277 |
| Issue: |
5 Pt 1 |
| Pages: |
C965-73 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chan KK |
| Year: |
2005 |
| Journal: |
Dev Dyn |
| Title: |
Hoxb3 vagal neural crest-specific enhancer element for controlling enteric nervous system development. |
| Volume: |
233 |
| Issue: |
2 |
| Pages: |
473-83 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Leclerc K |
| Year: |
2016 |
| Journal: |
Dev Dyn |
| Title: |
Mosaic analysis of cell rearrangements during ureteric bud branching in dissociated/reaggregated kidney cultures and in vivo. |
| Volume: |
245 |
| Issue: |
4 |
| Pages: |
483-96 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chia I |
| Year: |
2011 |
| Journal: |
Development |
| Title: |
Nephric duct insertion is a crucial step in urinary tract maturation that is regulated by a Gata3-Raldh2-Ret molecular network in mice. |
| Volume: |
138 |
| Issue: |
10 |
| Pages: |
2089-97 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Haque F |
| Year: |
2017 |
| Journal: |
Dev Biol |
| Title: |
Non-muscle myosin II deletion in the developing kidney causes ureter-bladder misconnection and apical extrusion of the nephric duct lineage epithelia. |
| Volume: |
427 |
| Issue: |
1 |
| Pages: |
121-130 |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
mutant stock, targeted mutation |
|
•
•
•
•
•
|
| Allele |
| Name: |
ret proto-oncogene; targeted mutation 1.1, David D Ginty |
| Allele Type: |
Targeted |
|
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
mutant stock, targeted mutation |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Grote D |
| Year: |
2008 |
| Journal: |
PLoS Genet |
| Title: |
Gata3 acts downstream of beta-catenin signaling to prevent ectopic metanephric kidney induction. |
| Volume: |
4 |
| Issue: |
12 |
| Pages: |
e1000316 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cui L |
| Year: |
2016 |
| Journal: |
Neuron |
| Title: |
Identification of Early RET+ Deep Dorsal Spinal Cord Interneurons in Gating Pain. |
| Volume: |
91 |
| Issue: |
5 |
| Pages: |
1137-1153 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Schneider S |
| Year: |
2024 |
| Journal: |
J Clin Invest |
| Title: |
BAP1 is required prenatally for differentiation and maintenance of postnatal murine enteric nervous system. |
| Volume: |
134 |
| Issue: |
9 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhang Y |
| Year: |
2012 |
| Journal: |
Genes Dev |
| Title: |
Phactr4 regulates directional migration of enteric neural crest through PP1, integrin signaling, and cofilin activity. |
| Volume: |
26 |
| Issue: |
1 |
| Pages: |
69-81 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ibiza S |
| Year: |
2016 |
| Journal: |
Nature |
| Title: |
Glial-cell-derived neuroregulators control type 3 innate lymphoid cells and gut defence. |
| Volume: |
535 |
| Issue: |
7612 |
| Pages: |
440-443 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Pomaville MB |
| Year: |
2023 |
| Journal: |
Neural Dev |
| Title: |
Follicle-innervating Aδ-low threshold mechanoreceptive neurons form receptive fields through homotypic competition. |
| Volume: |
18 |
| Issue: |
1 |
| Pages: |
2 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Majumdar A |
| Year: |
2003 |
| Journal: |
Development |
| Title: |
Wnt11 and Ret/Gdnf pathways cooperate in regulating ureteric branching during metanephric kidney development. |
| Volume: |
130 |
| Issue: |
14 |
| Pages: |
3175-85 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Fukuda N |
| Year: |
2003 |
| Journal: |
J Biol Chem |
| Title: |
Identification of a novel glial cell line-derived neurotrophic factor-inducible gene required for renal branching morphogenesis. |
| Volume: |
278 |
| Issue: |
50 |
| Pages: |
50386-92 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hasegawa T |
| Year: |
2008 |
| Journal: |
Oncogene |
| Title: |
Roles of induced expression of MAPK phosphatase-2 in tumor development in RET-MEN2A transgenic mice. |
| Volume: |
27 |
| Issue: |
43 |
| Pages: |
5684-95 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hoshi M |
| Year: |
2018 |
| Journal: |
J Am Soc Nephrol |
| Title: |
Reciprocal Spatiotemporally Controlled Apoptosis Regulates Wolffian Duct Cloaca Fusion. |
| Volume: |
29 |
| Issue: |
3 |
| Pages: |
775-783 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Anderson RB |
| Year: |
2006 |
| Journal: |
Gastroenterology |
| Title: |
The cell adhesion molecule l1 is required for chain migration of neural crest cells in the developing mouse gut. |
| Volume: |
130 |
| Issue: |
4 |
| Pages: |
1221-32 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kuure S |
| Year: |
2010 |
| Journal: |
PLoS Genet |
| Title: |
Actin depolymerizing factors cofilin1 and destrin are required for ureteric bud branching morphogenesis. |
| Volume: |
6 |
| Issue: |
10 |
| Pages: |
e1001176 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Schill EM |
| Year: |
2016 |
| Journal: |
Dev Biol |
| Title: |
Ibuprofen slows migration and inhibits bowel colonization by enteric nervous system precursors in zebrafish, chick and mouse. |
| Volume: |
409 |
| Issue: |
2 |
| Pages: |
473-88 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Langsdorf A |
| Year: |
2011 |
| Journal: |
Glycobiology |
| Title: |
Expression regulation and function of heparan sulfate 6-O-endosulfatases in the spermatogonial stem cell niche. |
| Volume: |
21 |
| Issue: |
2 |
| Pages: |
152-61 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bouheraoua N |
| Year: |
2019 |
| Journal: |
J Neurosci |
| Title: |
Genetic Analysis of the Organization, Development, and Plasticity of Corneal Innervation in Mice. |
| Volume: |
39 |
| Issue: |
7 |
| Pages: |
1150-1168 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Beermann F |
| Year: |
1999 |
| Journal: |
Cell Mol Biol (Noisy-le-grand) |
| Title: |
The tyrosinase related protein-1 (Tyrp1) promoter in transgenic experiments: targeted expression to the retinal pigment epithelium. |
| Volume: |
45 |
| Issue: |
7 |
| Pages: |
961-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kulkarni S |
| Year: |
2023 |
| Journal: |
Elife |
| Title: |
Age-associated changes in lineage composition of the enteric nervous system regulate gut health and disease. |
| Volume: |
12 |
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Canty AJ |
| Year: |
2009 |
| Journal: |
J Neurosci |
| Title: |
Regionalized loss of parvalbumin interneurons in the cerebral cortex of mice with deficits in GFRalpha1 signaling. |
| Volume: |
29 |
| Issue: |
34 |
| Pages: |
10695-705 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Uesaka T |
| Year: |
2015 |
| Journal: |
J Neurosci |
| Title: |
Neuronal Differentiation in Schwann Cell Lineage Underlies Postnatal Neurogenesis in the Enteric Nervous System. |
| Volume: |
35 |
| Issue: |
27 |
| Pages: |
9879-88 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Asai M |
| Year: |
1999 |
| Journal: |
Jpn J Cancer Res |
| Title: |
Differential regulation of MMP-9 and TIMP-2 expression in malignant melanoma developed in metallothionein/RET transgenic mice. |
| Volume: |
90 |
| Issue: |
1 |
| Pages: |
86-92 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Donnelly CR |
| Year: |
2018 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Biphasic functions for the GDNF-Ret signaling pathway in chemosensory neuron development and diversification. |
| Volume: |
115 |
| Issue: |
3 |
| Pages: |
E516-E525 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gonzalez-Reyes LE |
| Year: |
2012 |
| Journal: |
Neuron |
| Title: |
Sonic hedgehog maintains cellular and neurochemical homeostasis in the adult nigrostriatal circuit. |
| Volume: |
75 |
| Issue: |
2 |
| Pages: |
306-19 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wallace AS |
| Year: |
2010 |
| Journal: |
Neurobiol Dis |
| Title: |
L1cam acts as a modifier gene during enteric nervous system development. |
| Volume: |
40 |
| Issue: |
3 |
| Pages: |
622-33 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ledda F |
| Year: |
2007 |
| Journal: |
Nat Neurosci |
| Title: |
GDNF and GFRalpha1 promote formation of neuronal synapses by ligand-induced cell adhesion. |
| Volume: |
10 |
| Issue: |
3 |
| Pages: |
293-300 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Altés G |
| Year: |
2022 |
| Journal: |
Cell Mol Life Sci |
| Title: |
A dominant negative mutation uncovers cooperative control of caudal Wolffian duct development by Sprouty genes. |
| Volume: |
79 |
| Issue: |
10 |
| Pages: |
514 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hirst CS |
| Year: |
2017 |
| Journal: |
Sci Rep |
| Title: |
Kif1bp loss in mice leads to defects in the peripheral and central nervous system and perinatal death. |
| Volume: |
7 |
| Issue: |
1 |
| Pages: |
16676 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lake JI |
| Year: |
2013 |
| Journal: |
J Clin Invest |
| Title: |
Hirschsprung-like disease is exacerbated by reduced de novo GMP synthesis. |
| Volume: |
123 |
| Issue: |
11 |
| Pages: |
4875-87 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
287
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
281
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Frank MM |
| Year: |
2023 |
| Journal: |
Elife |
| Title: |
Experience-dependent flexibility in a molecularly diverse central-to-peripheral auditory feedback system. |
| Volume: |
12 |
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Uesaka T |
| Year: |
2021 |
| Journal: |
Glia |
| Title: |
Enhanced enteric neurogenesis by Schwann cell precursors in mouse models of Hirschsprung disease. |
| Volume: |
69 |
| Issue: |
11 |
| Pages: |
2575-2590 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Honma Y |
| Year: |
2010 |
| Journal: |
Development |
| Title: |
Axonal projections of mechanoreceptive dorsal root ganglion neurons depend on Ret. |
| Volume: |
137 |
| Issue: |
14 |
| Pages: |
2319-28 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Rossi J |
| Year: |
2000 |
| Journal: |
Eur J Neurosci |
| Title: |
Distinct roles for GFRalpha1 and GFRalpha2 signalling in different cranial parasympathetic ganglia in vivo. |
| Volume: |
12 |
| Issue: |
11 |
| Pages: |
3944-52 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Callahan T |
| Year: |
2008 |
| Journal: |
Glia |
| Title: |
Development of satellite glia in mouse sympathetic ganglia: GDNF and GFR alpha 1 are not essential. |
| Volume: |
56 |
| Issue: |
13 |
| Pages: |
1428-37 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gestblom C |
| Year: |
1999 |
| Journal: |
Am J Pathol |
| Title: |
Sympathoadrenal hyperplasia causes renal malformations in Ret(MEN2B)-transgenic mice. |
| Volume: |
155 |
| Issue: |
6 |
| Pages: |
2167-79 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lisse TS |
| Year: |
2020 |
| Journal: |
NPJ Regen Med |
| Title: |
GDNF promotes hair formation and cutaneous wound healing by targeting bulge stem cells. |
| Volume: |
5 |
|
| Pages: |
13 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kuehn ED |
| Year: |
2019 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Tiling and somatotopic alignment of mammalian low-threshold mechanoreceptors. |
| Volume: |
116 |
| Issue: |
19 |
| Pages: |
9168-9177 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kameneva P |
| Year: |
2021 |
| Journal: |
Nat Genet |
| Title: |
Single-cell transcriptomics of human embryos identifies multiple sympathoblast lineages with potential implications for neuroblastoma origin. |
| Volume: |
53 |
| Issue: |
5 |
| Pages: |
694-706 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nishiyama C |
| Year: |
2012 |
| Journal: |
Nat Neurosci |
| Title: |
Trans-mesenteric neural crest cells are the principal source of the colonic enteric nervous system. |
| Volume: |
15 |
| Issue: |
9 |
| Pages: |
1211-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hoshi M |
| Year: |
2012 |
| Journal: |
Development |
| Title: |
Novel mechanisms of early upper and lower urinary tract patterning regulated by RetY1015 docking tyrosine in mice. |
| Volume: |
139 |
| Issue: |
13 |
| Pages: |
2405-15 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Furlan A |
| Year: |
2013 |
| Journal: |
EMBO J |
| Title: |
The transcription factor Hmx1 and growth factor receptor activities control sympathetic neurons diversification. |
| Volume: |
32 |
| Issue: |
11 |
| Pages: |
1613-25 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Almeida AR |
| Year: |
2012 |
| Journal: |
PLoS One |
| Title: |
RET/GFRα signals are dispensable for thymic T cell development in vivo. |
| Volume: |
7 |
| Issue: |
12 |
| Pages: |
e52949 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Michos O |
| Year: |
2010 |
| Journal: |
PLoS Genet |
| Title: |
Kidney development in the absence of Gdnf and Spry1 requires Fgf10. |
| Volume: |
6 |
| Issue: |
1 |
| Pages: |
e1000809 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Pozas E |
| Year: |
2005 |
| Journal: |
Neuron |
| Title: |
GDNF and GFRalpha1 promote differentiation and tangential migration of cortical GABAergic neurons. |
| Volume: |
45 |
| Issue: |
5 |
| Pages: |
701-13 |
|
•
•
•
•
•
|