MouseMine: Keyword Search

Publication

First Author:	Venkitachalam S
Year:	2012
Journal:	Biochem Biophys Res Commun
Title:	Nuclear localization of lymphocyte-specific protein tyrosine kinase (Lck) and its role in regulating LIM domain only 2 (Lmo2) gene.
Volume:	417
Issue:	3
Pages:	1058-62

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Publication

22083669 | J:181808

First Author:	Nakai M
Year:	2012
Journal:	Lab Invest
Title:	Characterization of novel germline c-kit gene mutation, KIT-Tyr553Cys, observed in a family with multiple gastrointestinal stromal tumors.
Volume:	92
Issue:	3
Pages:	451-7

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Publication

21388519 | J:187555

First Author:	Mynott AV
Year:	2011
Journal:	FEBS J
Title:	Crystal structure of importin-α bound to a peptide bearing the nuclear localisation signal from chloride intracellular channel protein 4.
Volume:	278
Issue:	10
Pages:	1662-75

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Publication

23085512 | J:192853

First Author:	Tang H
Year:	2013
Journal:	J Mol Cell Cardiol
Title:	Overexpression of TNNI3K, a cardiac-specific MAPKKK, promotes cardiac dysfunction.
Volume:	54

Pages:	101-11

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Publication

24984260 | J:214963

First Author:	Yen ST
Year:	2014
Journal:	Dev Biol
Title:	Somatic mosaicism and allele complexity induced by CRISPR/Cas9 RNA injections in mouse zygotes.
Volume:	393
Issue:	1
Pages:	3-9

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Publication

31042421 | J:277816

First Author:	Liu L
Year:	2019
Journal:	Am J Physiol Cell Physiol
Title:	MicroRNA-140 inhibits skeletal muscle glycolysis and atrophy in endotoxin-induced sepsis in mice via the WNT signaling pathway.
Volume:	317
Issue:	2
Pages:	C189-C199

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Publication

20590640 | J:278272

First Author:	Ledonne A
Year:	2010
Journal:	Br J Pharmacol
Title:	Trace amines depress D(2)-autoreceptor-mediated responses on midbrain dopaminergic cells.
Volume:	160
Issue:	6
Pages:	1509-20

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Publication

32029227 | J:285388

First Author:	Barnes TM
Year:	2020
Journal:	Mol Metab
Title:	Identification of the leptin receptor sequences crucial for the STAT3-Independent control of metabolism.
Volume:	32

Pages:	168-175

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Publication

34073081 | J:312227

First Author:	Gmoshinski IV
Year:	2021
Journal:	Int J Mol Sci
Title:	Effects of Tyrosine and Tryptophan Supplements on the Vital Indicators in Mice Differently Prone to Diet-Induced Obesity.
Volume:	22
Issue:	11

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Publication

35615698 | J:325076

First Author:	Yan X
Year:	2022
Journal:	Front Cell Dev Biol
Title:	Myocilin Gene Mutation Induced Autophagy Activation Causes Dysfunction of Trabecular Meshwork Cells.
Volume:	10

Pages:	900777

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Strain

MGI:3578786 | STOCK Plp1<jp> x C3H101HF1/H

Attribute String:

spontaneous mutation, mutant stock

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Allele

Tyr<c> | MGI:1855976

Name:	tyrosinase; albino
Allele Type:	Spontaneous

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Genotype

Symbol:	War/War Tyr/Tyr
Background:	PBI
Zygosity:	cx
Has Mutant Allele:	true

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Publication

6165997 | J:6520

First Author:	Gates FT 3rd
Year:	1981
Journal:	Proc Natl Acad Sci U S A
Title:	Complete amino acid sequence of murine beta 2-microglobulin: structural evidence for strain-related polymorphism.
Volume:	78
Issue:	1
Pages:	554-8

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Publication

3199070 | J:106337

First Author:	Hemmi S
Year:	1988
Journal:	J Exp Med
Title:	Three spontaneous H-2Db mutants are generated by genetic micro-recombination (gene conversion) events. Impact on the H-2-restricted immune responsiveness.
Volume:	168
Issue:	6
Pages:	2319-35

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Publication

24551160 | J:213356

First Author:	Patton DT
Year:	2014
Journal:	PLoS One
Title:	The development and survival but not function of follicular B cells is dependent on IL-7Rα Tyr449 signaling.
Volume:	9
Issue:	2
Pages:	e88771

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Publication

28637841 | J:244898

First Author:	Nakamura F
Year:	2017
Journal:	J Neurosci
Title:	Protein Tyrosine Phosphatase δ Mediates the Sema3A-Induced Cortical Basal Dendritic Arborization through the Activation of Fyn Tyrosine Kinase.
Volume:	37
Issue:	30
Pages:	7125-7139

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Publication

21423209 | J:317230

First Author:	Wagh PK
Year:	2011
Journal:	Oncogene
Title:	β-Catenin is required for Ron receptor-induced mammary tumorigenesis.
Volume:	30
Issue:	34
Pages:	3694-704

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Publication

11514605 | J:71099

First Author:	Magnan A
Year:	2001
Journal:	J Exp Med
Title:	T cell development and T cell responses in mice with mutations affecting tyrosines 292 or 315 of the ZAP-70 protein tyrosine kinase.
Volume:	194
Issue:	4
Pages:	491-505

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Publication

11420611 | J:70379

First Author:	Cohen RM
Year:	2001
Journal:	Mamm Genome
Title:	Quantitative trait loci affecting the behavior of A/J and CBA/J intercross mice in the elevated plus maze.
Volume:	12
Issue:	7
Pages:	501-7

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Publication

1664788 | J:76

First Author:	Mita T
Year:	1991
Journal:	Brain Res Dev Brain Res
Title:	Unusual biochemical development of genetically seizure-susceptible El mice.
Volume:	64
Issue:	1-2
Pages:	27-35

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Publication

16332273 | J:106118

First Author:	Pinto LH
Year:	2005
Journal:	Vis Neurosci
Title:	Generation, characterization, and molecular cloning of the Noerg-1 mutation of rhodopsin in the mouse.
Volume:	22
Issue:	5
Pages:	619-29

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Publication

18202316 | J:147657

First Author:	Yu N
Year:	2008
Journal:	Circ Res
Title:	Binding of the P2Y2 nucleotide receptor to filamin A regulates migration of vascular smooth muscle cells.
Volume:	102
Issue:	5
Pages:	581-8

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Publication

1382097 | J:2705

First Author:	Fernandez C
Year:	1992
Journal:	J Immunol
Title:	Genetic mechanisms for dominant VH gene expression. The VHB512 gene.
Volume:	149
Issue:	7
Pages:	2328-36

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Publication

7522165 | J:20946

First Author:	Venkitaraman AR
Year:	1994
Journal:	Eur J Immunol
Title:	Interleukin-7 induces the association of phosphatidylinositol 3-kinase with the alpha chain of the interleukin-7 receptor.
Volume:	24
Issue:	9
Pages:	2168-74

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Publication

7868915 | J:23721

First Author:	Santamaria P
Year:	1995
Journal:	J Immunol
Title:	Beta-cell-cytotoxic CD8+ T cells from nonobese diabetic mice use highly homologous T cell receptor alpha-chain CDR3 sequences.
Volume:	154
Issue:	5
Pages:	2494-503

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Publication

9565625 | J:47859

First Author:	Richards RG
Year:	1998
Journal:	J Biol Chem
Title:	Insulin-like growth factor-1 (IGF-1) receptor-insulin receptor substrate complexes in the uterus. Altered signaling response to estradiol in the IGF-1(m/m) mouse.
Volume:	273
Issue:	19
Pages:	11962-9

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Publication

29489891 | J:260343

First Author:	Helfenberger KE
Year:	2018
Journal:	PLoS One
Title:	Subcellular distribution of ERK phosphorylation in tyrosine and threonine depends on redox status in murine lung cells.
Volume:	13
Issue:	2
Pages:	e0193022

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Publication

30269370 | J:295639

First Author:	McCabe IC
Year:	2019
Journal:	J Cell Biochem
Title:	Novel leptin receptor signaling mutants identify location and sex-dependent modulation of bone density, adiposity, and growth.
Volume:	120
Issue:	3
Pages:	4398-4408

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Publication

15561106 | J:94595

First Author:	Continolo S
Year:	2005
Journal:	Exp Cell Res
Title:	The proto-oncogene Fgr regulates cell migration and this requires its plasma membrane localization.
Volume:	302
Issue:	2
Pages:	253-69

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Publication

21746961 | J:177211

First Author:	Lee JH
Year:	2011
Journal:	J Immunol
Title:	The Src family kinase Fgr is critical for activation of mast cells and IgE-mediated anaphylaxis in mice.
Volume:	187
Issue:	4
Pages:	1807-15

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Publication

17208428 | -

First Author:	Ihle JN
Year:	2007
Journal:	Curr Opin Genet Dev
Title:	Jak2: normal function and role in hematopoietic disorders.
Volume:	17
Issue:	1
Pages:	8-14

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Publication

11175259 | -

First Author:	Lippens S
Year:	2000
Journal:	Cell Death Differ
Title:	Epidermal differentiation does not involve the pro-apoptotic executioner caspases, but is associated with caspase-14 induction and processing.
Volume:	7
Issue:	12
Pages:	1218-24

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Publication

11726498 | -

First Author:	Stammers DK
Year:	2001
Journal:	EMBO J
Title:	The structure of the negative transcriptional regulator NmrA reveals a structural superfamily which includes the short-chain dehydrogenase/reductases.
Volume:	20
Issue:	23
Pages:	6619-26

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Publication

18602114 | -

First Author:	Kotaka M
Year:	2008
Journal:	J Mol Biol
Title:	Structural analysis of the recognition of the negative regulator NmrA and DNA by the zinc finger from the GATA-type transcription factor AreA.
Volume:	381
Issue:	2
Pages:	373-82

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Publication

18263583 | -

First Author:	Zhao Y
Year:	2008
Journal:	J Biol Chem
Title:	An NADPH sensor protein (HSCARG) down-regulates nitric oxide synthesis by association with argininosuccinate synthetase and is essential for epithelial cell viability.
Volume:	283
Issue:	16
Pages:	11004-13

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Publication

10784047 | -

First Author:	Dow JM
Year:	2000
Journal:	Microbiology
Title:	Novel genes involved in the regulation of pathogenicity factor production within the rpf gene cluster of Xanthomonas campestris.
Volume:	146 ( Pt 4)

Pages:	885-91

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Publication

11121154 | -

First Author:	Eckhart L
Year:	2000
Journal:	J Invest Dermatol
Title:	Terminal differentiation of human keratinocytes and stratum corneum formation is associated with caspase-14 activation.
Volume:	115
Issue:	6
Pages:	1148-51

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Publication

12200134 | -

First Author:	Chien AJ
Year:	2002
Journal:	Biochem Biophys Res Commun
Title:	Processing of native caspase-14 occurs at an atypical cleavage site in normal epidermal differentiation.
Volume:	296
Issue:	4
Pages:	911-7

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Publication

15301553 | -

First Author:	Mikolajczyk J
Year:	2004
Journal:	Biochemistry
Title:	Activation and substrate specificity of caspase-14.
Volume:	43
Issue:	32
Pages:	10560-9

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Publication

21841788 | -

First Author:	Ungureanu D
Year:	2011
Journal:	Nat Struct Mol Biol
Title:	The pseudokinase domain of JAK2 is a dual-specificity protein kinase that negatively regulates cytokine signaling.
Volume:	18
Issue:	9
Pages:	971-6

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Publication

17466371 | -

First Author:	Karow A
Year:	2008
Journal:	Leuk Res
Title:	JAK2 mutations other than V617F: a novel mutation and mini review.
Volume:	32
Issue:	2
Pages:	365-6

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Publication

15475610 | -

First Author:	Sandberg EM
Year:	2004
Journal:	Cell Biochem Biophys
Title:	Jak2 tyrosine kinase: a true jak of all trades?
Volume:	41
Issue:	2
Pages:	207-32

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Publication

17133099 | -

First Author:	Levine RL
Year:	2007
Journal:	Curr Opin Hematol
Title:	JAK-2 mutations and their relevance to myeloproliferative disease.
Volume:	14
Issue:	1
Pages:	43-7

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Publication

17389152 | -

First Author:	Hsu HC
Year:	2007
Journal:	J Chin Med Assoc
Title:	Pathogenetic role of JAK2 V617F mutation in chronic myeloproliferative disorders.
Volume:	70
Issue:	3
Pages:	89-93

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Publication

16810614 | -

First Author:	Bellucci S
Year:	2006
Journal:	Semin Thromb Hemost
Title:	The role of JAK2 V617F mutation, spontaneous erythropoiesis and megakaryocytopoiesis, hypersensitive platelets, activated leukocytes, and endothelial cells in the etiology of thrombotic manifestations in polycythemia vera and essential thrombocythemia.
Volume:	32
Issue:	4 Pt 2
Pages:	381-98

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Publication

10066823 | -

First Author:	Brunati AM
Year:	1999
Journal:	J Biol Chem
Title:	Molecular features underlying the sequential phosphorylation of HS1 protein and its association with c-Fgr protein-tyrosine kinase.
Volume:	274
Issue:	11
Pages:	7557-64

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Publication

29089387 | -

First Author:	Casey AK
Year:	2017
Journal:	J Biol Chem
Title:	Fic-mediated deAMPylation is not dependent on homodimerization and rescues toxic AMPylation in flies.
Volume:	292
Issue:	51
Pages:	21193-21204

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Publication

25601083 | -

First Author:	Sanyal A
Year:	2015
Journal:	J Biol Chem
Title:	A novel link between Fic (filamentation induced by cAMP)-mediated adenylylation/AMPylation and the unfolded protein response.
Volume:	290
Issue:	13
Pages:	8482-99

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Publication

11676921 | -

First Author:	Walker DM
Year:	2001
Journal:	Curr Biol
Title:	Characterization of MTMR3. an inositol lipid 3-phosphatase with novel substrate specificity.
Volume:	11
Issue:	20
Pages:	1600-5

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Publication

10733931 | -

First Author:	Zhao R
Year:	2000
Journal:	Biochem Biophys Res Commun
Title:	FYVE-DSP1, a dual-specificity protein phosphatase containing an FYVE domain.
Volume:	270
Issue:	1
Pages:	222-9

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Publication

30944173 | J:280417

First Author:	Dewi Pamungkas Putri D
Year:	2019
Journal:	J Biol Chem
Title:	PtdIns3P phosphatases MTMR3 and MTMR4 negatively regulate innate immune responses to DNA through modulating STING trafficking.
Volume:	294
Issue:	21
Pages:	8412-8423

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Publication

25659891 | -

First Author:	St-Denis N
Year:	2015
Journal:	Mol Cell Proteomics
Title:	Myotubularin-related proteins 3 and 4 interact with polo-like kinase 1 and centrosomal protein of 55 kDa to ensure proper abscission.
Volume:	14
Issue:	4
Pages:	946-60

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Protein Domain

IPR033174 | Caspase-14

Type:

Family

Description:

Caspase-14 (MEROPS identifier C14.018) is a cytoplasmic cysteine endopeptidase found only in cornifying tissues such as skin. It is found in epidermal keratinocytes and is involved in a tissue-specific form of senescence, leading to differentiation of keratinocytes to form the cornified cell layer [, ]. Caspase-14 is synthesized as a zymogen, but, unusually for a caspase, activation is not autocatalytic, and cleavage to produce the p20 and p10 subunits occurs in human caspase-14 at Ile152 []. Caspase-14 has a strict requirement for Asp in the P1 position, and positional scanning of substrates shows a preference for hydrophobic residues such as Trp or Tyr in P4 [].

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Protein Domain

IPR040198 | Fido_containing

Type:

Family

Description:

Proteins in this entry contain a fido domain. The domain is named after the Fic and Doc proteins where it is found. Included in this entry are adenosine monophosphate-protein transferase Fic and FICD. Both Fic and FICD add adenosine 5'-monophosphate (AMP) to specific residues of target proteins (AMPylation), or remove the same modification from target proteins (de-AMPylation), depending on whether cells are in a resting state or stressed []. Both bind divalent cations, preferring Mn2+over Mg2+[]. The adenosine monophosphate-protein transferase SoFic from Shewanella oneidensis is known only to add AMP to target proteins, either at Tyr or Thr residues [].

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Protein Domain

IPR012379 | LytTR_MHYE

Type:

Family

Description:

Members of this group combine the LytTR DNA-binding transcriptional regulator domain []with an N-terminal membrane-bound MHYE domain that consists of three predicted transmembrane segments with conserved Glu, Asp, His and Tyr residues. The membrane topology of this domain is somewhat similar to that of MHYT domain [], suggesting that it, too, might be membrane-bound and metal-binding [].A member of this group is RpfD from the plant pathogen Xanthomonas campestris. Although the rpfDgene is located in the rpf(regulation of pathogenicity factors) locus of X. campestris, mutants with transposon insertion in the rpfDgene did not exhibit any discernible phenotype []. The function of this protein is not yet known.

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Protein Domain

IPR035693 | Fgr_SH2

Type:

Domain

Description:

Tyrosine-protein kinase Fgr belongs to the SRC family of the Tyr protein kinases. It is a non-receptor tyrosine-protein kinase that transmits signals from cell surface receptors devoid of kinase activity and contributes to the regulation of immune responses, including neutrophil, monocyte, macrophage and mast cell functions, cytoskeleton remodeling in response to extracellular stimuli, phagocytosis, cell adhesion and migration [, , ]. It contains a protein kinase domain, an SH2 domain and an SH3 domain. Fgr interacts with tyrosine phosphorylated SYK, FLT3 and HCLS1 via its SH2 domain [].This entry represents the SH2 domain of Fgr.

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Protein Domain

IPR046352 | MTMR3_Pase_dom

Type:

Domain

Description:

This entry represents the phosphatase domain of Myotubularin-related protein 3 (Mtmf3). Proteins in this entry are specific to chordates. Mtmr3 is a phosphatase that acts on lipids with a phosphoinositol head-group such as phosphatidyl-inositol 3-phosphate and phosphatidyl-inositol 3,5-bisphosphate []. It may also de-phosphorylate proteins phosphorylated on Ser, Thr, and Tyr residues []. This enzyme has shown to play a regulatory role in the regulation of abscission, the final step of mitosis [], and innate immune responses to viral DNA through the modulation of STING trafficking [].

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Protein Domain

IPR015914 | Purple_acid_Pase_N

Type:

Domain

Description:

Purple acid phosphatases (PAPs) are ubiquitous binuclear metal-containing acid hydrolases characterised by their acidic pH optima and their intense purple colour due to a TyrO-to-FeIII charge-transfer transition. The amino acid residues coordinating the metal ions are conserved in all PAPs. Active PAPs contain an FeIII ion coordinated to Tyr O, a His N, and an Asp O2, in addition to a divalent metal ion (Fe, Zn, or Mn) coordinated by a His N, a His N, and an Asn O. A hydroxide ion and an Asp O2 bridge the two metal ions []. These enzymes share a high degree of homology within their N-termini [].

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Protein Domain

IPR008030 | NmrA-like

Type:

Domain

Description:

NmrA is a negative transcriptional regulator of various fungi, involved in the post-translational modulation of the GATA-type transcription factor AreA []. NmrA lacks the canonical GXXGXXG NAD-binding motif and has altered residues at the catalytic triad, including a Met instead of the critical Tyr residue. NmrA may bind nucleotides but appears to lack any dehydrogenase activity. It lacks most of the active site residues of the SDR (short-chain dehydrogenases/reductases) family, but has an NAD(P)-binding motif similar to the extended SDR family, GXXGXXG [].This domain can also be found in other atypical SDRs, such as HSCARG (an NADPH sensor) []and PCBER (phenylcoumaran benzylic ether reductase) [].

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Publication

20308425 | J:158805

First Author:	Zito E
Year:	2010
Journal:	J Cell Biol
Title:	ERO1-beta, a pancreas-specific disulfide oxidase, promotes insulin biogenesis and glucose homeostasis.
Volume:	188
Issue:	6
Pages:	821-32

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Publication

23410753 | J:200802

First Author:	Kobayashi H
Year:	2013
Journal:	Biochem Biophys Res Commun
Title:	Ablation of Rnf213 retards progression of diabetes in the Akita mouse.
Volume:	432
Issue:	3
Pages:	519-25

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Publication

24391519 | J:226670

First Author:	Moayedi Y
Year:	2014
Journal:	PLoS Genet
Title:	The candidate splicing factor Sfswap regulates growth and patterning of inner ear sensory organs.
Volume:	10
Issue:	1
Pages:	e1004055

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Strain

MGI:3044545 | C3H101H A/A<w>-Hbb<d>/Hbb<d4>/H

Attribute String:

mutant stock, chemically induced mutation

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Publication

21641382 | J:173296

First Author:	Lu A
Year:	2011
Journal:	Am J Pathol
Title:	Blockade of TSP1-dependent TGF-β activity reduces renal injury and proteinuria in a murine model of diabetic nephropathy.
Volume:	178
Issue:	6
Pages:	2573-86

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Publication

26389675 | J:226393

First Author:	Sharma RB
Year:	2015
Journal:	J Clin Invest
Title:	Insulin demand regulates β cell number via the unfolded protein response.
Volume:	125
Issue:	10
Pages:	3831-46

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Publication

20955341 | J:165705

First Author:	Fang RC
Year:	2010
Journal:	Wound Repair Regen
Title:	Limitations of the db/db mouse in translational wound healing research: Is the NONcNZO10 polygenic mouse model superior?
Volume:	18
Issue:	6
Pages:	605-13

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Publication

18219478 | J:137936

First Author:	Liu Z
Year:	2008
Journal:	Diabetologia
Title:	Mice with beta cell overexpression of glycogen synthase kinase-3beta have reduced beta cell mass and proliferation.
Volume:	51
Issue:	4
Pages:	623-31

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Publication

34086738 | J:312122

First Author:	Dhounchak S
Year:	2021
Journal:	PLoS One
Title:	Heparan sulfate proteoglycans in beta cells provide a critical link between endoplasmic reticulum stress, oxidative stress and type 2 diabetes.
Volume:	16
Issue:	6
Pages:	e0252607

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Publication

33872860 | J:316885

First Author:	Altamura S
Year:	2021
Journal:	Mol Metab
Title:	Iron aggravates hepatic insulin resistance in the absence of inflammation in a novel db/db mouse model with iron overload.
Volume:	51

Pages:	101235

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Publication

19773578 | J:159566

First Author:	Cheng L
Year:	2009
Journal:	Am J Physiol Endocrinol Metab
Title:	A regulatory role of LPCAT1 in the synthesis of inflammatory lipids, PAF and LPC, in the retina of diabetic mice.
Volume:	297
Issue:	6
Pages:	E1276-82

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Publication

29061652 | J:291014

First Author:	Harlan SM
Year:	2018
Journal:	J Am Soc Nephrol
Title:	Progressive Renal Disease Established by Renin-Coding Adeno-Associated Virus-Driven Hypertension in Diverse Diabetic Models.
Volume:	29
Issue:	2
Pages:	477-491

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Publication

- | J:13046

First Author:	Deol MS
Year:	1954
Journal:	J Genet
Title:	The anomalies of the labyrinth of the mutants varitint-waddler, shaker-2 and jerker in the mouse.
Volume:	52
Issue:	3
Pages:	562-588

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Publication

21139688 | J:168105

First Author:	Kern TS
Year:	2010
Journal:	Mol Vis
Title:	Validation of structural and functional lesions of diabetic retinopathy in mice.
Volume:	16

Pages:	2121-31

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Publication

35044843 | J:334959

First Author:	Halford J
Year:	2022
Journal:	Mol Biol Cell
Title:	Ca²⁺ entry through mechanotransduction channels localizes BAIAP2L2 to stereocilia tips.
Volume:	33
Issue:	4
Pages:	br6

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Publication

37011103 | J:346281

First Author:	Krey JF
Year:	2023
Journal:	PLoS Biol
Title:	Control of stereocilia length during development of hair bundles.
Volume:	21
Issue:	4
Pages:	e3001964

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Publication

19522984 | J:164953

First Author:	Giehl KA
Year:	2009
Journal:	Clin Exp Dermatol
Title:	Hair interior defect in AKR/J mice.
Volume:	34
Issue:	4
Pages:	509-17

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Publication

26306834 | J:258757

First Author:	Booler HS
Year:	2016
Journal:	Brain Pathol
Title:	Degree of Cajal-Retzius Cell Mislocalization Correlates with the Severity of Structural Brain Defects in Mouse Models of Dystroglycanopathy.
Volume:	26
Issue:	4
Pages:	465-78

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Publication

32005704 | J:287303

First Author:	Mochida T
Year:	2020
Journal:	Diabetes
Title:	Insulin-Deficient Diabetic Condition Upregulates the Insulin-Secreting Capacity of Human Induced Pluripotent Stem Cell-Derived Pancreatic Endocrine Progenitor Cells After Implantation in Mice.
Volume:	69
Issue:	4
Pages:	634-646

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Strain

MGI:5000308 | D2.Cg-Apoe<tm1Unc> Ins2<Akita>/J

Attribute String:

congenic, mutant strain, targeted mutation, spontaneous mutation

•

Strain

MGI:5007923 | B6.Cg-Apoe<tm1Unc> Ins2<Akita>/J

Attribute String:

congenic, mutant strain, targeted mutation, spontaneous mutation

•

Publication

21447785 | J:182074

First Author:	Jun JY
Year:	2011
Journal:	Am J Physiol Endocrinol Metab
Title:	Spontaneously diabetic Ins2(+/Akita):apoE-deficient mice exhibit exaggerated hypercholesterolemia and atherosclerosis.
Volume:	301
Issue:	1
Pages:	E145-54

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Publication

31970899 | J:305682

First Author:	Madonna R
Year:	2020
Journal:	J Cell Mol Med
Title:	Co-expression of glycosylated aquaporin-1 and transcription factor NFAT5 contributes to aortic stiffness in diabetic and atherosclerosis-prone mice.
Volume:	24
Issue:	5
Pages:	2857-2865

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Publication

34381972 | J:350641

First Author:	Bouchareychas L
Year:	2021
Journal:	iScience
Title:	High glucose macrophage exosomes enhance atherosclerosis by driving cellular proliferation & hematopoiesis.
Volume:	24
Issue:	8
Pages:	102847

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Publication

36243046 | J:341647

First Author:	Mastrogiacomo L
Year:	2023
Journal:	Am J Pathol
Title:	The Effects of Hyperglycemia on Early Endothelial Activation and the Initiation of Atherosclerosis.
Volume:	193
Issue:	1
Pages:	121-133

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Strain

MGI:3713278 | B6.Cg-Ins2<Akita> Bdkrb2<tm1Jfh>/SmiJ

Attribute String:

congenic, mutant strain, spontaneous mutation, targeted mutation

•

Strain

MGI:3626097 | B6.Cg-Ins2<Akita> Bdkrb2<tm1Jfh>

Attribute String:

congenic, mutant strain, spontaneous mutation, targeted mutation

•

Publication

23019230 | J:190320

First Author:	Vashistha H
Year:	2012
Journal:	Am J Physiol Renal Physiol
Title:	Null mutations at the p66 and bradykinin 2 receptor loci induce divergent phenotypes in the diabetic kidney.
Volume:	303
Issue:	12
Pages:	F1629-40

•

Publication

16604193 | J:108948

First Author:	Kakoki M
Year:	2006
Journal:	J Clin Invest
Title:	Senescence-associated phenotypes in Akita diabetic mice are enhanced by absence of bradykinin B2 receptors.
Volume:	116
Issue:	5
Pages:	1302-9

•

Publication

15326315 | J:92403

First Author:	Kakoki M
Year:	2004
Journal:	Proc Natl Acad Sci U S A
Title:	Diabetic nephropathy is markedly enhanced in mice lacking the bradykinin B2 receptor.
Volume:	101
Issue:	36
Pages:	13302-5

•

Publication

20479236 | J:161075

First Author:	Kakoki M
Year:	2010
Journal:	Proc Natl Acad Sci U S A
Title:	Lack of both bradykinin B1 and B2 receptors enhances nephropathy, neuropathy, and bone mineral loss in Akita diabetic mice.
Volume:	107
Issue:	22
Pages:	10190-5

•

Strain

MGI:3700930 | B6.Cg-Ins2<Akita> Ldlr<tm1Her>/J

Attribute String:

congenic, mutant strain, spontaneous mutation, targeted mutation

•

Publication

21606463 | J:174983

First Author:	Zhou C
Year:	2011
Journal:	J Lipid Res
Title:	Hyperglycemic Ins2AkitaLdlr⁻/⁻ mice show severely elevated lipid levels and increased atherosclerosis: a model of type 1 diabetic macrovascular disease.
Volume:	52
Issue:	8
Pages:	1483-93

•

Publication

24677271 | J:249668

First Author:	Bjørklund MM
Year:	2014
Journal:	Circ Res
Title:	Induction of atherosclerosis in mice and hamsters without germline genetic engineering.
Volume:	114
Issue:	11
Pages:	1684-9

•

Publication

21245338 | J:169115

First Author:	Wang CH
Year:	2011
Journal:	Proc Natl Acad Sci U S A
Title:	A modest decrease in endothelial NOS in mice comparable to that associated with human NOS3 variants exacerbates diabetic nephropathy.
Volume:	108
Issue:	5
Pages:	2070-5

•

Publication

23649519 | J:208962

First Author:	Abudukadier A
Year:	2013
Journal:	Diabetes
Title:	Tetrahydrobiopterin has a glucose-lowering effect by suppressing hepatic gluconeogenesis in an endothelial nitric oxide synthase-dependent manner in diabetic mice.
Volume:	62
Issue:	9
Pages:	3033-43

•

Publication

31380462 | J:286353

First Author:	Verma A
Year:	2019
Journal:	Mol Ther Methods Clin Dev
Title:	Expression of Human ACE2 in Lactobacillus and Beneficial Effects in Diabetic Retinopathy in Mice.
Volume:	14

Pages:	161-170

•

Publication

33713581 | J:325388

First Author:	Wetzel MD
Year:	2021
Journal:	Physiol Rep
Title:	Homoarginine ameliorates diabetic nephropathy independent of nitric oxide synthase-3.
Volume:	9
Issue:	5
Pages:	e14766

•

Strain

MGI:2179472 | B6.Cg-Rag1<tm1Mom> Ins2<Akita>/J

Attribute String:

congenic, mutant strain, targeted mutation, spontaneous mutation

•

Publication

24743240 | J:215198

First Author:	Kikawa K
Year:	2014
Journal:	PLoS One
Title:	Beneficial effect of insulin treatment on islet transplantation outcomes in Akita mice.
Volume:	9
Issue:	4
Pages:	e95451

•

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