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Search results 16301 to 16400 out of 2418182 for a

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Type Details Score
Publication
7831294 | J:22521
First Author: DiSanto JP
Year: 1995
Journal: Proc Natl Acad Sci U S A
Title: Lymphoid development in mice with a targeted deletion of the interleukin 2 receptor gamma chain.
Volume: 92
Issue: 2
Pages: 377-81
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Publication
28653618 | J:258209
   
First Author: Chorghade S
Year: 2017
Journal: Elife
Title: Poly(A) tail length regulates PABPC1 expression to tune translation in the heart.
Volume: 6
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Publication
17197418 | J:119080
First Author: Inzunza J
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Ovarian wedge resection restores fertility in estrogen receptor beta knockout (ERbeta-/-) mice.
Volume: 104
Issue: 2
Pages: 600-5
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Publication
37272425 | J:359326
   
First Author: Huff A
Year: 2023
Journal: Elife
Title: Role of the postinspiratory complex in regulating swallow-breathing coordination and other laryngeal behaviors.
Volume: 12
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Publication
38134531 | J:358631
 
First Author: de Zélicourt A
Year: 2024
Journal: Cell Calcium
Title: Two-pore channels (TPCs) acts as a hub for excitation-contraction coupling, metabolism and cardiac hypertrophy signalling.
Volume: 117
Pages: 102839
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Publication
29909970 | J:265932
First Author: Wang QA
Year: 2018
Journal: Cell Metab
Title: Reversible De-differentiation of Mature White Adipocytes into Preadipocyte-like Precursors during Lactation.
Volume: 28
Issue: 2
Pages: 282-288.e3
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Publication
507473 | J:6234
First Author: Groen A
Year: 1979
Journal: Anim Blood Groups Biochem Genet
Title: Genetically determined electrophoretic variants of the major urinary protein (Mup) complex in mouse urine.
Volume: 10
Issue: 2
Pages: 107-14
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Publication
21945298 | J:177514
First Author: Bahi A
Year: 2012
Journal: Behav Brain Res
Title: Involvement of tissue plasminogen activator "tPA" in ethanol-induced locomotor sensitization and conditioned-place preference.
Volume: 226
Issue: 1
Pages: 250-8
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Publication
27910071 | J:320634
 
First Author: Joshi A
Year: 2017
Journal: Adv Exp Med Biol
Title: PI3K/PTEN/AKT Genetic Mouse Models of Endometrial Carcinoma.
Volume: 943
Pages: 261-273
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Publication
17512409 | -
First Author: Shimada A
Year: 2007
Journal: Cell
Title: Curved EFC/F-BAR-domain dimers are joined end to end into a filament for membrane invagination in endocytosis.
Volume: 129
Issue: 4
Pages: 761-72
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Publication
31340201 | J:353168
     
First Author: Scoville D
Year: 2019
Journal: J Endocrinol
Title: GLIS3 binds pancreatic beta cell regulatory regions alongside other islet transcription factors.
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Publication
20876097 | J:165407
First Author: Feng J
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Calcium-sensing receptor is a physiologic multimodal chemosensor regulating gastric G-cell growth and gastrin secretion.
Volume: 107
Issue: 41
Pages: 17791-6
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Publication
16581901 | J:108289
First Author: Raoul C
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Chronic activation in presymptomatic amyotrophic lateral sclerosis (ALS) mice of a feedback loop involving Fas, Daxx, and FasL.
Volume: 103
Issue: 15
Pages: 6007-12
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Publication
16814781 | -
First Author: Lama A
Year: 2006
Journal: FEBS Lett
Title: Oxygen binding and NO scavenging properties of truncated hemoglobin, HbN, of Mycobacterium smegmatis.
Volume: 580
Issue: 17
Pages: 4031-41
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Protein
P05125
Organism: Mus musculus/domesticus
Length: 152  
Fragment?: false
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Publication
20381429 | J:160847
First Author: Choudhury A
Year: 2010
Journal: Clin Immunol
Title: B cells require "nurturing" by CD4 T cells during development in order to respond in chronic graft-versus-host model of systemic lupus erythematosus.
Volume: 136
Issue: 1
Pages: 105-15
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Publication
30257940 | J:266607
First Author: Jamrog L
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: PAX5-ELN oncoprotein promotes multistep B-cell acute lymphoblastic leukemia in mice.
Volume: 115
Issue: 41
Pages: 10357-10362
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Publication
15363888 | J:93203
First Author: Munemoto Y
Year: 2004
Journal: Brain Res Mol Brain Res
Title: Mouse homolog of KIAA0143 protein: hearing deficit induces specific changes of expression in auditory brainstem neurons.
Volume: 128
Issue: 2
Pages: 131-40
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Publication
15102711 | J:262504
First Author: Chan EM
Year: 2004
Journal: Hum Mol Genet
Title: Laforin preferentially binds the neurotoxic starch-like polyglucosans, which form in its absence in progressive myoclonus epilepsy.
Volume: 13
Issue: 11
Pages: 1117-29
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Publication
12630757 | -
First Author: Racila DM
Year: 2003
Journal: Lupus
Title: Homozygous single nucleotide polymorphism of the complement C1QA gene is associated with decreased levels of C1q in patients with subacute cutaneous lupus erythematosus.
Volume: 12
Issue: 2
Pages: 124-32
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Publication
19087315 | J:145740
 
First Author: Lovas A
Year: 2008
Journal: BMC Genomics
Title: Differential RelA- and RelB-dependent gene transcription in LTbetaR-stimulated mouse embryonic fibroblasts.
Volume: 9
Pages: 606
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Publication
10963667 | J:64379
First Author: Li Z
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: A role for Timeless in epithelial morphogenesis during kidney development.
Volume: 97
Issue: 18
Pages: 10038-43
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Publication
31227742 | J:279904
First Author: Roth JD
Year: 2019
Journal: Sci Rep
Title: Combined obeticholic acid and elafibranor treatment promotes additive liver histological improvements in a diet-induced ob/ob mouse model of biopsy-confirmed NASH.
Volume: 9
Issue: 1
Pages: 9046
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Protein
Q8BV96
Organism: Mus musculus/domesticus
Length: 336  
Fragment?: true
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Publication
19217813 | J:147881
First Author: Champigny MJ
Year: 2009
Journal: Mol Genet Metab
Title: A point mutation in the neu1 promoter recruits an ectopic repressor, Nkx3.2 and results in a mouse model of sialidase deficiency.
Volume: 97
Issue: 1
Pages: 43-52
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Publication
1715974 | -
First Author: Martineau B
Year: 1991
Journal: Mol Gen Genet
Title: Regulation of metallocarboxypeptidase inhibitor gene expression in tomato.
Volume: 228
Issue: 1-2
Pages: 281-6
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Protein Domain
IPR018550 | Lipid-A_deacylase-rel
Type: Family
Description: PagL is an outer membrane protein with lipid A 3-O-deacylase activity. It forms an 8 stranded beta barrel structure [].
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Protein Domain
IPR004231 | COpept_A_inh-like
Type: Domain
Description: In molecular biology, the carboxypeptidase A inhibitor family is a family of proteins which is represented by the well-characterised metallocarboxypeptidase A inhibitor (MCPI) from potatoes, which belongs to the MEROPS inhibitor family I37, clan IE. It inhibits metallopeptidases belonging to MEROPS peptidase family M14, carboxypeptidase A.Proteins with this domain include metallocarboxypeptidase inhibitor (MCPI) and fruit-specific protein. MCPI may play a defensive role against insect attacks [].
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Protein Domain
IPR020821 | Extracellular_endonuc_su_A
Type: Domain
Description: A family of bacterial and eukaryotic endonucleases share the following characteristics: they act on both DNA and RNA, cleave double-stranded and single-stranded nucleic acids and require a divalent ion such as magnesium for their activity. A histidine has been shown []to be essential for the activity of the Serratia marcescens nuclease. This residue is located in a conserved region which also contains an aspartic acid residue that could be implicated in the binding of the divalent ion.
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Protein Domain
IPR040161 | FB155/FB224
Type: Family
Description: This entry includes a group of F-box proteins from Caenorhabditis, including FB155 and FB224. Their function is not clear.
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Protein Domain
IPR013435 | Mobile_mystery_prot_A
Type: Family
Description: Proteins in this entry are more often encoded within mobilisation-related contexts than not. This includes a CRISPR-associated gene region in Geobacter sulfurreducens PCA, and plasmids in Agrobacterium tumefaciens and Coxiella burnetii. They are found together with mobile mystery protein B, a member of the Fic protein family (). Mobile mystery protein A is encoded by the upstream member of the gene pair and contains a helix-turn-helix domain.
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Protein Domain
IPR013626 | PaO
Type: Domain
Description: This domain is found in bacterial and plant proteins to the C terminus of a Rieske 2Fe-2S domain (). One of the proteins the domain is found in is Pheophorbide a oxygenase (PaO) which seems to be a key regulator of chlorophyll catabolism. Arabidopsis PaO (AtPaO) is a Rieske-type 2Fe-2S enzyme that is identical to Arabidopsis accelerated cell death 1 and homologous to lethal leaf spot 1 (LLS1) of maize [], in which the domain described here is also found.
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Publication
2322568 | J:10406
First Author: Matsunaga T
Year: 1990
Journal: Biochemistry
Title: Structure and in vitro transcription of the rat CYP2A1 and CYP2A2 genes and regional localization of the CYP2A gene subfamily on mouse chromosome 7.
Volume: 29
Issue: 5
Pages: 1329-41
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Publication
29735674 | J:262491
First Author: Esteve-Rudd J
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Defective phagosome motility and degradation in cell nonautonomous RPE pathogenesis of a dominant macular degeneration.
Volume: 115
Issue: 21
Pages: 5468-5473
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Publication
22988104 | J:190111
First Author: Walsh ER
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Dual signaling by innate and adaptive immune receptors is required for TLR7-induced B-cell-mediated autoimmunity.
Volume: 109
Issue: 40
Pages: 16276-81
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Publication
1465455 | J:129537
First Author: Fabry ME
Year: 1992
Journal: Proc Natl Acad Sci U S A
Title: High expression of human beta S- and alpha-globins in transgenic mice: erythrocyte abnormalities, organ damage, and the effect of hypoxia.
Volume: 89
Issue: 24
Pages: 12155-9
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Publication
26046931 | J:237711
First Author: Pinho AV
Year: 2015
Journal: PLoS One
Title: Pancreas-Specific Sirt1-Deficiency in Mice Compromises Beta-Cell Function without Development of Hyperglycemia.
Volume: 10
Issue: 6
Pages: e0128012
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Publication
11217864 | J:111264
First Author: Demetriou M
Year: 2001
Journal: Nature
Title: Negative regulation of T-cell activation and autoimmunity by Mgat5 N-glycosylation.
Volume: 409
Issue: 6821
Pages: 733-9
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Publication
18949514 | J:144618
First Author: Weichenhan D
Year: 2008
Journal: Mamm Genome
Title: A mouse translocation associated with Caspr5-2 disruption and perinatal lethality.
Volume: 19
Issue: 10-12
Pages: 675-86
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Protein
P54869
Organism: Mus musculus/domesticus
Length: 508  
Fragment?: false
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Publication
24210219 | -
First Author: Tchigvintsev A
Year: 2013
Journal: Chem Biol
Title: Biochemical and structural studies of conserved Maf proteins revealed nucleotide pyrophosphatases with a preference for modified nucleotides.
Volume: 20
Issue: 11
Pages: 1386-98
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Publication
16740638 | -
First Author: Beloqui A
Year: 2006
Journal: J Biol Chem
Title: Novel polyphenol oxidase mined from a metagenome expression library of bovine rumen: biochemical properties, structural analysis, and phylogenetic relationships.
Volume: 281
Issue: 32
Pages: 22933-42
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Publication
35225230 | J:323616
   
First Author: Grimaldi A
Year: 2022
Journal: Elife
Title: Identification of bipotent progenitors that give rise to myogenic and connective tissues in mouse.
Volume: 11
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Publication
9729467 | J:85284
 
First Author: Sorokin A
Year: 1998
Journal: Biochem J
Title: Insulin stimulates the tyrosine dephosphorylation of docking protein p130cas (Crk-associated substrate), promoting the switch of the adaptor protein crk from p130cas to newly phosphorylated insulin receptor substrate-1.
Volume: 334 ( Pt 3)
Pages: 595-600
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Publication
15048718 | J:88856
First Author: Kuroki A
Year: 2004
Journal: Eur J Immunol
Title: Enforced Bcl-2 expression in B lymphocytes induces rheumatoid factor and anti-DNA production, but the Yaa mutation promotes only anti-DNA production.
Volume: 34
Issue: 4
Pages: 1077-84
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Publication
19538944 | J:151681
First Author: Kawanami A
Year: 2009
Journal: Biochem Biophys Res Commun
Title: Mice expressing GFP and CreER in osteochondro progenitor cells in the periosteum.
Volume: 386
Issue: 3
Pages: 477-82
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Publication
36130516 | J:358727
First Author: Levi A
Year: 2022
Journal: Cell Rep
Title: Error correction and improved precision of spike timing in converging cortical networks.
Volume: 40
Issue: 12
Pages: 111383
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Publication
33846328 | J:315002
First Author: Bonnan A
Year: 2021
Journal: Nat Commun
Title: Autonomous Purkinje cell activation instructs bidirectional motor learning through evoked dendritic calcium signaling.
Volume: 12
Issue: 1
Pages: 2153
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Publication
30913225 | J:273457
First Author: Prabhakar A
Year: 2019
Journal: PLoS One
Title: Leaky expression of channelrhodopsin-2 (ChR2) in Ai32 mouse lines.
Volume: 14
Issue: 3
Pages: e0213326
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Publication
10191088 | J:54668
First Author: Fujii T
Year: 1999
Journal: Genomics
Title: Sperizin is a murine RING zinc-finger protein specifically expressed in Haploid germ cells.
Volume: 57
Issue: 1
Pages: 94-101
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Publication
15358863 | J:92604
First Author: Prange O
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: A balance between excitatory and inhibitory synapses is controlled by PSD-95 and neuroligin.
Volume: 101
Issue: 38
Pages: 13915-20
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Publication
19745153 | J:152220
First Author: Sada A
Year: 2009
Journal: Science
Title: The RNA-binding protein NANOS2 is required to maintain murine spermatogonial stem cells.
Volume: 325
Issue: 5946
Pages: 1394-8
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Publication
22065784 | J:180170
First Author: Triplett JW
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Competition is a driving force in topographic mapping.
Volume: 108
Issue: 47
Pages: 19060-5
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Publication
17942483 | J:125485
First Author: Walz A
Year: 2007
Journal: Development
Title: Axonal wiring of guanylate cyclase-D-expressing olfactory neurons is dependent on neuropilin 2 and semaphorin 3F.
Volume: 134
Issue: 22
Pages: 4063-72
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Publication
26984772 | J:250062
 
First Author: Li A
Year: 2016
Journal: BMC Biol
Title: Mesodermal ALK5 controls lung myofibroblast versus lipofibroblast cell fate.
Volume: 14
Pages: 19
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Publication
33157254 | J:317169
 
First Author: Werdermann M
Year: 2021
Journal: Mol Metab
Title: Insulin and obesity transform hypothalamic-pituitary-adrenal axis stemness and function in a hyperactive state.
Volume: 43
Pages: 101112
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Publication
32631996 | J:292265
First Author: Wu H
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: A negative reciprocal regulatory axis between cyclin D1 and HNF4α modulates cell cycle progression and metabolism in the liver.
Volume: 117
Issue: 29
Pages: 17177-17186
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Publication
31548403 | J:280400
First Author: Beurg M
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: A Tmc1 mutation reduces calcium permeability and expression of mechanoelectrical transduction channels in cochlear hair cells.
Volume: 116
Issue: 41
Pages: 20743-20749
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Publication
39461344 | J:358427
First Author: Liao Y
Year: 2024
Journal: Cell Metab
Title: Amino acid is a major carbon source for hepatic lipogenesis.
Volume: 36
Issue: 11
Pages: 2437-2448.e8
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Publication
2780558 | J:19284
First Author: Cheng GH
Year: 1989
Journal: Proc Natl Acad Sci U S A
Title: Different 3'-end processing produces two independently regulated mRNAs from a single H1 histone gene.
Volume: 86
Issue: 18
Pages: 7002-6
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Publication
19812696 | J:154101
First Author: Rohrbeck A
Year: 2009
Journal: PLoS One
Title: Cancer genomics identifies regulatory gene networks associated with the transition from dysplasia to advanced lung adenocarcinomas induced by c-Raf-1.
Volume: 4
Issue: 10
Pages: e7315
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Protein Coding Gene
MGI:1921409 | Acbd5
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
27849619 | J:239095
First Author: Bergström JH
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Gram-positive bacteria are held at a distance in the colon mucus by the lectin-like protein ZG16.
Volume: 113
Issue: 48
Pages: 13833-13838
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Publication
17895430 | J:129984
First Author: Ran Q
Year: 2007
Journal: J Gerontol A Biol Sci Med Sci
Title: Reduction in glutathione peroxidase 4 increases life span through increased sensitivity to apoptosis.
Volume: 62
Issue: 9
Pages: 932-42
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Publication
24303183 | J:229588
First Author: Mukharji A
Year: 2013
Journal: Physiol Rep
Title: Oxyntomodulin increases intrinsic heart rate through the glucagon receptor.
Volume: 1
Issue: 5
Pages: e00112
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Publication
12151307 | J:116258
First Author: Rosendahl A
Year: 2002
Journal: Am J Respir Cell Mol Biol
Title: Activation of bone morphogenetic protein/Smad signaling in bronchial epithelial cells during airway inflammation.
Volume: 27
Issue: 2
Pages: 160-9
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Publication
1313565 | J:45
First Author: Nagpal S
Year: 1992
Journal: Proc Natl Acad Sci U S A
Title: RAR-beta 4, a retinoic acid receptor isoform is generated from RAR-beta 2 by alternative splicing and usage of a CUG initiator codon.
Volume: 89
Issue: 7
Pages: 2718-22
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Protein
Q8BNV1
Organism: Mus musculus/domesticus
Length: 613  
Fragment?: false
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Protein
E9PUQ7
Organism: Mus musculus/domesticus
Length: 613  
Fragment?: false
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Publication
7930572 | J:131345
First Author: Paterson RK
Year: 1994
Journal: J Immunol
Title: Thymic development in human CD4 transgenic mice. Positive selection occurs after commitment to the CD8 lineage.
Volume: 153
Issue: 8
Pages: 3491-503
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Publication
15983210 | J:100092
First Author: Roccisana J
Year: 2005
Journal: Diabetes
Title: Targeted inactivation of hepatocyte growth factor receptor c-met in beta-cells leads to defective insulin secretion and GLUT-2 downregulation without alteration of beta-cell mass.
Volume: 54
Issue: 7
Pages: 2090-102
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Publication
24089510 | J:209045
First Author: Alvarez-Perez JC
Year: 2014
Journal: Diabetes
Title: Hepatocyte growth factor/c-Met signaling is required for β-cell regeneration.
Volume: 63
Issue: 1
Pages: 216-23
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Publication
15056934 | J:88536
First Author: Ishikawa A
Year: 2004
Journal: Genes Genet Syst
Title: Mapping major quantitative trait loci for postnatal growth in an intersubspecific backcross between C57BL/6J and Philippine wild mice by using principal component analysis.
Volume: 79
Issue: 1
Pages: 27-39
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Publication
25641263 | J:224572
First Author: Pombero A
Year: 2015
Journal: J Comp Neurol
Title: The α2-subunit of the nicotinic cholinergic receptor is specifically expressed in medial subpallium-derived cells of mammalian amygdala.
Volume: 523
Issue: 11
Pages: 1608-21
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GO Term
GO:0019226 | transmission of nerve impulse
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GO Term
GO:0001014 | snoRNA transcription by RNA polymerase III
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Publication
17563351 | J:122381
First Author: d'Anglemont de Tassigny X
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Hypogonadotropic hypogonadism in mice lacking a functional Kiss1 gene.
Volume: 104
Issue: 25
Pages: 10714-9
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Publication
30587001 | J:291420
First Author: Chipont A
Year: 2019
Journal: Arterioscler Thromb Vasc Biol
Title: MicroRNA-21 Deficiency Alters the Survival of Ly-6Clo Monocytes in ApoE-/- Mice and Reduces Early-Stage Atherosclerosis-Brief Report.
Volume: 39
Issue: 2
Pages: 170-177
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Publication
31255288 | J:291765
First Author: Wang H
Year: 2019
Journal: Biochem Biophys Res Commun
Title: ORMDL3 knockdown in the lungs alleviates airway inflammation and airway remodeling in asthmatic mice via JNK1/2-MMP-9 pathway.
Volume: 516
Issue: 3
Pages: 739-746
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Protein
Q3TAZ6
Organism: Mus musculus/domesticus
Length: 312  
Fragment?: false
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Publication
24101730 | J:225481
First Author: Scorziello A
Year: 2013
Journal: J Cell Sci
Title: NCX3 regulates mitochondrial Ca(2+) handling through the AKAP121-anchored signaling complex and prevents hypoxia-induced neuronal death.
Volume: 126
Issue: Pt 24
Pages: 5566-77
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Publication
18779586 | J:141274
First Author: Lamia KA
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Physiological significance of a peripheral tissue circadian clock.
Volume: 105
Issue: 39
Pages: 15172-7
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Publication
22470452 | J:187130
First Author: Reinert RB
Year: 2012
Journal: PLoS One
Title: Tamoxifen-Induced Cre-loxP Recombination Is Prolonged in Pancreatic Islets of Adult Mice.
Volume: 7
Issue: 3
Pages: e33529
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Publication
37691621 | J:351851
 
First Author: Sayles NM
Year: 2023
Journal: Dis Model Mech
Title: Comparative multi-omic analyses of cardiac mitochondrial stress in three mouse models of frataxin deficiency.
Volume: 16
Issue: 10
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Publication
28459456 | J:260585
First Author: De Iaco A
Year: 2017
Journal: Nat Genet
Title: DUX-family transcription factors regulate zygotic genome activation in placental mammals.
Volume: 49
Issue: 6
Pages: 941-945
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Publication
8058792 | J:19904
First Author: Larue L
Year: 1994
Journal: Proc Natl Acad Sci U S A
Title: E-cadherin null mutant embryos fail to form a trophectoderm epithelium.
Volume: 91
Issue: 17
Pages: 8263-7
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Publication
20660762 | J:164406
First Author: Chiang PM
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Deletion of TDP-43 down-regulates Tbc1d1, a gene linked to obesity, and alters body fat metabolism.
Volume: 107
Issue: 37
Pages: 16320-4
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Publication
33674596 | J:304975
First Author: Ischenko I
Year: 2021
Journal: Nat Commun
Title: KRAS drives immune evasion in a genetic model of pancreatic cancer.
Volume: 12
Issue: 1
Pages: 1482
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Publication
17110443 | J:117145
First Author: Salido EC
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Alanine-glyoxylate aminotransferase-deficient mice, a model for primary hyperoxaluria that responds to adenoviral gene transfer.
Volume: 103
Issue: 48
Pages: 18249-54
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Publication
25481868 | -
 
First Author: Torres-Flores JM
Year: 2015
Journal: Virology
Title: The tight junction protein JAM-A functions as coreceptor for rotavirus entry into MA104 cells.
Volume: 475
Pages: 172-8
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Protein Domain
IPR026498 | Grasp_w_spasm_A
Type: Domain
Description: This entry represent the leader peptide domain, ending in a Gly-Gly cleavage motif, for a post-ribosomal natural product (PRNP) precursor. The corresponding modification enzymes include an ATP-GRASP enzyme and a SPASM-domain protein, related to the C-terminal region of numerous peptide-modification radical SAM enzymes.
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Protein Domain
IPR000491 | Inhibin_betaA
Type: Family
Description: Inhibins and activins are glycoproteins, secreted by the gonads, that belong to the transforming growth factor beta family []. They participate in differentiation and growth of diverse cell types. Inhibin inhibits secretion of follicle-stimulating hormone by the pituitary []. Inhibin has two isoforms, A and B, with the same alpha subunit but different beta subunits. Inhibin A is a dimer of alpha and beta A subunits, inhibin B is a dimer of alpha and beta B subunits. Activin A is a dimer of beta A subunits, activin AB is a dimer of beta A and beta B chains. Follistatin is bound to inhibin and activin and indirectly modulates the FSH release. In turn, FSH stimulates inhibin gene expression in the ovarian follicle [], probably mediated by cAMP []. The serum levels of inhibin, activin, and follistatin are elevated in pregnant women and decrease after delivery []. Genes coding for mouse activin beta C and beta E are closely linked and exhibit a liver-specific expression pattern in adult tissues.This entry represents inhibin beta A subunit.
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Protein Domain
IPR012997 | RplA
Type: Domain
Description: Rare lipoprotein A (RlpA) is an outer membrane protein that localises to the septal ring and scattered foci along the lateral wall in Escherichia coli. In Pseudomonas aeruginosa, RlpA is a lytic transglycosylase with preference for naked glycan strands that is needed for efficient separation of daughter cells and maintenance of rod shape [].This entry represents a conserved region in RlpA and RlpA-like proteins.
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Protein Domain
IPR042456 | F11R
Type: Family
Description: F11R, also known as Junctional adhesion molecule A (JAM-1), belongs to the immunoglobulin superfamily. It is a cell adhesion molecule involved in platelet aggregation []and in transendothelial migration of leukocytes []. It binds PAR-3, and may recruit PAR-3 to tight junctions []. JAM-1 has also been shown to act as a receptor for Mammalian reovirus sigma-1 []and Human Rotavirus strain Wa [].
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Protein Domain
IPR040950 | GAIN_A
Type: Domain
Description: GPR56 is a a cell-surface G protein-coupled receptor (GPCR) which belongs to the adhesion G protein-coupled receptor (aGPCR) family, a large family of chimeric proteins that have both adhesion and signaling functions and play critical roles in diverse neurobiological processes including brain development, synaptogenesis, and myelination. This entry represents GPCR-Autoproteolysis-INducing (GAIN) subdomain A, including PLL-GAIN linker (F161-D175) region [].
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Publication
27855162 | J:239748
First Author: McMahon M
Year: 2016
Journal: PLoS Biol
Title: ADAMTS5 Is a Critical Regulator of Virus-Specific T Cell Immunity.
Volume: 14
Issue: 11
Pages: e1002580
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Publication
16172982 | J:105760
First Author: Swetloff A
Year: 2005
Journal: Int J Dev Biol
Title: Changes in E2F5 intracellular localization in mouse and human choroid plexus epithelium with development.
Volume: 49
Issue: 7
Pages: 859-65
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Publication
11751631 | J:73468
First Author: Fisher GH
Year: 2001
Journal: Genes Dev
Title: Induction and apoptotic regression of lung adenocarcinomas by regulation of a K-Ras transgene in the presence and absence of tumor suppressor genes.
Volume: 15
Issue: 24
Pages: 3249-62
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HT Experiment
E-MEXP-3504 | Transcription profiling by array of liver from proestrus and metestrus mice to investigate ER control of liver metabolic function
 
Experiment Type: transcription profiling by array
Study Type: Baseline
Source: ArrayExpress
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Publication
2532311 | J:27910
First Author: Wieraszko A
Year: 1989
Journal: Neurosci Lett
Title: Increased amount of extracellular ATP in stimulated hippocampal slices of seizure prone mice.
Volume: 106
Issue: 3
Pages: 287-93
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