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  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
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Search results 1701 to 1800 out of 2004 for Arc

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0.028s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Protein
U5LIX2
Organism: Mus musculus/domesticus
Length: 749  
Fragment?: true
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Protein
Q14B43
Organism: Mus musculus/domesticus
Length: 699  
Fragment?: false
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Protein
V9PCB9
Organism: Mus musculus/domesticus
Length: 748  
Fragment?: true
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Protein
U5LL62
Organism: Mus musculus/domesticus
Length: 749  
Fragment?: true
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Protein
V9PCD3
Organism: Mus musculus/domesticus
Length: 748  
Fragment?: true
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Protein
V9PC30
Organism: Mus musculus/domesticus
Length: 748  
Fragment?: true
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Protein
V9PC06
Organism: Mus musculus/domesticus
Length: 748  
Fragment?: true
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Protein
A9DA50
Organism: Mus musculus/domesticus
Length: 620  
Fragment?: false
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Protein
Q3UV88
Organism: Mus musculus/domesticus
Length: 806  
Fragment?: false
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Protein
V9PCB6
Organism: Mus musculus/domesticus
Length: 748  
Fragment?: true
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Protein
V9PC22
Organism: Mus musculus/domesticus
Length: 748  
Fragment?: true
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Protein
Q7TSD1
Organism: Mus musculus/domesticus
Length: 78  
Fragment?: false
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Protein
Q6PHP6
Organism: Mus musculus/domesticus
Length: 730  
Fragment?: false
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Protein
V9PC08
Organism: Mus musculus/domesticus
Length: 748  
Fragment?: true
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Protein
Q05AH3
Organism: Mus musculus/domesticus
Length: 859  
Fragment?: false
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Protein
F2Z425
Organism: Mus musculus/domesticus
Length: 86  
Fragment?: false
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Protein
G3UXX4
Organism: Mus musculus/domesticus
Length: 883  
Fragment?: false
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Protein
Q8BJ09
Organism: Mus musculus/domesticus
Length: 432  
Fragment?: true
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Protein
U5LIT9
Organism: Mus musculus/domesticus
Length: 749  
Fragment?: true
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Protein
F8WHU3
Organism: Mus musculus/domesticus
Length: 706  
Fragment?: false
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Protein
V9PBW6
Organism: Mus musculus/domesticus
Length: 748  
Fragment?: true
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Protein
B7ZN36
Organism: Mus musculus/domesticus
Length: 606  
Fragment?: false
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Protein
Q811T5
Organism: Mus musculus/domesticus
Length: 784  
Fragment?: false
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Protein
Q3TM31
Organism: Mus musculus/domesticus
Length: 905  
Fragment?: false
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Protein
F8VPR1
Organism: Mus musculus/domesticus
Length: 595  
Fragment?: false
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Protein
A0A217FL76
Organism: Mus musculus/domesticus
Length: 708  
Fragment?: false
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Protein
A0A286YDA0
Organism: Mus musculus/domesticus
Length: 466  
Fragment?: false
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Protein
V9PBV4
Organism: Mus musculus/domesticus
Length: 748  
Fragment?: true
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Protein
A0A146E664
Organism: Mus musculus/domesticus
Length: 428  
Fragment?: false
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Protein
A0A0U1RPZ9
Organism: Mus musculus/domesticus
Length: 86  
Fragment?: true
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Protein
U5LL15
Organism: Mus musculus/domesticus
Length: 749  
Fragment?: true
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Protein
Q0PM14
Organism: Mus musculus/domesticus
Length: 806  
Fragment?: false
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Protein
A0A0A6YVY4
Organism: Mus musculus/domesticus
Length: 873  
Fragment?: false
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Protein
Q499F3
Organism: Mus musculus/domesticus
Length: 905  
Fragment?: false
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Protein
A0A286YCV8
Organism: Mus musculus/domesticus
Length: 489  
Fragment?: false
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Protein
Q9R015
Organism: Mus musculus/domesticus
Length: 597  
Fragment?: false
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Protein
Q8BMW6
Organism: Mus musculus/domesticus
Length: 385  
Fragment?: false
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Protein
L0CL36
Organism: Mus musculus/domesticus
Length: 835  
Fragment?: false
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Protein
Q4VBE6
Organism: Mus musculus/domesticus
Length: 519  
Fragment?: false
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Protein
V9PC21
Organism: Mus musculus/domesticus
Length: 748  
Fragment?: true
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Protein
A0A0U1RPF1
Organism: Mus musculus/domesticus
Length: 82  
Fragment?: true
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Protein
Q8K3D9
Organism: Mus musculus/domesticus
Length: 784  
Fragment?: false
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Protein
Q3U297
Organism: Mus musculus/domesticus
Length: 766  
Fragment?: false
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Protein
V9PBW8
Organism: Mus musculus/domesticus
Length: 748  
Fragment?: true
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Protein
V9PC89
Organism: Mus musculus/domesticus
Length: 748  
Fragment?: true
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Protein
U5LHT6
Organism: Mus musculus/domesticus
Length: 749  
Fragment?: true
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Protein
Q6A0E8
Organism: Mus musculus/domesticus
Length: 727  
Fragment?: true
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Protein
L0CMZ8
Organism: Mus musculus/domesticus
Length: 835  
Fragment?: false
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Protein
Q7TPC5
Organism: Mus musculus/domesticus
Length: 806  
Fragment?: false
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Protein
Q8K2T5
Organism: Mus musculus/domesticus
Length: 835  
Fragment?: false
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Protein
Q8CB40
Organism: Mus musculus/domesticus
Length: 853  
Fragment?: true
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Protein
D3Z5M7
Organism: Mus musculus/domesticus
Length: 307  
Fragment?: false
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Protein
Q3UHE3
Organism: Mus musculus/domesticus
Length: 476  
Fragment?: false
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Protein
A0A172Q382
Organism: Mus musculus/domesticus
Length: 735  
Fragment?: true
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Protein
V9PC13
Organism: Mus musculus/domesticus
Length: 748  
Fragment?: true
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Protein
D3YYQ3
Organism: Mus musculus/domesticus
Length: 751  
Fragment?: true
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Protein
Q6US92
Organism: Mus musculus/domesticus
Length: 730  
Fragment?: false
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Protein
V9PC15
Organism: Mus musculus/domesticus
Length: 748  
Fragment?: true
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Protein
B2RQD4
Organism: Mus musculus/domesticus
Length: 606  
Fragment?: false
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Protein
A0A286YDA3
Organism: Mus musculus/domesticus
Length: 492  
Fragment?: false
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Protein
G3UXI8
Organism: Mus musculus/domesticus
Length: 835  
Fragment?: false
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Protein
E9Q009
Organism: Mus musculus/domesticus
Length: 105  
Fragment?: false
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Protein
A0A1Y7VNL1
Organism: Mus musculus/domesticus
Length: 760  
Fragment?: false
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Protein
Q3V0B5
Organism: Mus musculus/domesticus
Length: 596  
Fragment?: false
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Protein
G3X8Y8
Organism: Mus musculus/domesticus
Length: 784  
Fragment?: false
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Protein
B5BQV4
Organism: Mus musculus/domesticus
Length: 455  
Fragment?: false
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Protein
V9PBZ6
Organism: Mus musculus/domesticus
Length: 748  
Fragment?: true
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Protein
B9EJ46
Organism: Mus musculus/domesticus
Length: 795  
Fragment?: false
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Protein
V9PCC9
Organism: Mus musculus/domesticus
Length: 748  
Fragment?: true
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Protein
U5LL67
Organism: Mus musculus/domesticus
Length: 749  
Fragment?: true
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Protein
B2RRI5
Organism: Mus musculus/domesticus
Length: 1047  
Fragment?: false
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Protein
A2BHU8
Organism: Mus musculus/domesticus
Length: 154  
Fragment?: false
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Protein
Q1ZZX0
Organism: Mus musculus/domesticus
Length: 859  
Fragment?: false
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Protein
A2RSS9
Organism: Mus musculus/domesticus
Length: 117  
Fragment?: false
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Protein
V9PCD6
Organism: Mus musculus/domesticus
Length: 748  
Fragment?: true
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Protein
V9PCC4
Organism: Mus musculus/domesticus
Length: 748  
Fragment?: true
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Protein
V9PC34
Organism: Mus musculus/domesticus
Length: 748  
Fragment?: true
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Protein
V9PC11
Organism: Mus musculus/domesticus
Length: 748  
Fragment?: true
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Protein
V9PC02
Organism: Mus musculus/domesticus
Length: 748  
Fragment?: true
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Protein
V9PBW5
Organism: Mus musculus/domesticus
Length: 748  
Fragment?: true
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Protein
V9PC40
Organism: Mus musculus/domesticus
Length: 748  
Fragment?: true
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Protein
V9PC18
Organism: Mus musculus/domesticus
Length: 748  
Fragment?: true
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Protein
V9PC51
Organism: Mus musculus/domesticus
Length: 748  
Fragment?: true
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Protein
V9PCD0
Organism: Mus musculus/domesticus
Length: 748  
Fragment?: true
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Protein
V9PC04
Organism: Mus musculus/domesticus
Length: 748  
Fragment?: true
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Protein
V9PBW7
Organism: Mus musculus/domesticus
Length: 748  
Fragment?: true
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Publication
9690478 | -
First Author: Garrett TP
Year: 1998
Journal: Nature
Title: Crystal structure of the first three domains of the type-1 insulin-like growth factor receptor.
Volume: 394
Issue: 6691
Pages: 395-9
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Publication
1943695 | -
First Author: Weissbach H
Year: 1991
Journal: Mol Microbiol
Title: Regulation of methionine synthesis in Escherichia coli.
Volume: 5
Issue: 7
Pages: 1593-7
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Publication
12526809 | -
First Author: Schubert WD
Year: 2002
Journal: Cell
Title: Structure of internalin, a major invasion protein of Listeria monocytogenes, in complex with its human receptor E-cadherin.
Volume: 111
Issue: 6
Pages: 825-36
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Publication
15003459 | -
First Author: Freiberg A
Year: 2004
Journal: J Mol Biol
Title: Folding and stability of the leucine-rich repeat domain of internalin B from Listeri monocytogenes.
Volume: 337
Issue: 2
Pages: 453-61
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Publication
7817399 | -
First Author: Kobe B
Year: 1994
Journal: Trends Biochem Sci
Title: The leucine-rich repeat: a versatile binding motif.
Volume: 19
Issue: 10
Pages: 415-21
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Protein Domain
IPR012569 | LRR-contain_adjacent_dom
Type: Domain
Description: Leucine-rich repeats (LRR) consist of 2-45 motifs of 20-30 amino acids in length that generally folds into an arc or horseshoe shape []. LRRs occur in proteins ranging from viruses to eukaryotes, and appear to provide a structural framework for the formation of protein-protein interactions [, ].Proteins containing LRRs include tyrosine kinase receptors, cell-adhesion molecules, virulence factors, and extracellular matrix-binding glycoproteins, and are involved in a variety of biological processes, including signal transduction, cell adhesion, DNA repair, recombination, transcription, RNA processing, disease resistance, apoptosis, and the immune response [, ].Sequence analyses of LRR proteins suggested the existence of several different subfamilies of LRRs. The significance of this classification is that repeats from different subfamilies never occur simultaneously and have most probably evolved independently. It is, however, now clear that all major classes of LRR have curved horseshoe structures with a parallel beta sheet on the concave side and mostly helical elements on the convex side. At least six families of LRR proteins, characterised by different lengths and consensus sequences of the repeats, have been identified. Eleven-residue segments of the LRRs (LxxLxLxxN/CxL), corresponding to the β-strand and adjacent loop regions, are conserved in LRR proteins, whereas the remaining parts of the repeats (herein termed variable) may be very different. Despite the differences, each of the variable parts contains two half-turns at both ends and a "linear"segment (as the chain follows a linear path overall), usually formed by a helix, in the middle. The concave face and the adjacent loops are the most common protein interaction surfaces on LRR proteins. 3D structure of some LRR proteins-ligand complexes show that the concave surface of LRR domain is ideal for interaction with α-helix, thus supporting earlier conclusions that the elongated and curved LRR structure provides an outstanding framework for achieving diverse protein-protein interactions []. Molecular modeling suggests that the conserved pattern LxxLxL, which is shorter than the previously proposed LxxLxLxxN/CxL is sufficient to impart the characteristic horseshoe curvature to proteins with 20- to 30-residue repeats []. These are small, all beta strand domains, structurally described for the protein Internalin (InlA) and related proteins InlB, InlC, InlH from the pathogenic bacterium Listeria monocytogenes. Their function appears to be mainly structural: They are fused to the C-terminal end of leucine-rich repeats (LRR), significantly stabilising the LRR, and forming a common rigid entity with the LRR. They are themselves not involved in protein-protein-interactions but help to present the adjacent LRR-domain for this purpose. These domains belong to the family of Ig-like domains in that they consist of two sandwiched beta sheets that follow the classical connectivity of Ig-domains. The beta strands in one of the sheets is, however, much smaller than in most standard Ig-like domains, making it somewhat of an outlier [, , , ].
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Protein
Q80TM9
Organism: Mus musculus/domesticus
Length: 1593  
Fragment?: false
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Protein
Q66X03
Organism: Mus musculus/domesticus
Length: 949  
Fragment?: false
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Protein
P79621
Organism: Mus musculus/domesticus
Length: 1155  
Fragment?: false
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Protein
Q8BU40
Organism: Mus musculus/domesticus
Length: 982  
Fragment?: false
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Protein
Q8C6J9
Organism: Mus musculus/domesticus
Length: 863  
Fragment?: false
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Protein
Q3TKR3
Organism: Mus musculus/domesticus
Length: 982  
Fragment?: false
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Protein
Q66X19
Organism: Mus musculus/domesticus
Length: 978  
Fragment?: false
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Protein
Q66X05
Organism: Mus musculus/domesticus
Length: 959  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom