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Search results 1701 to 1800 out of 1910 for Atoh1

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Type Details Score
Publication
First Author: Li P
Year: 2016
Journal: Cancer Res
Title: Nestin Mediates Hedgehog Pathway Tumorigenesis.
Volume: 76
Issue: 18
Pages: 5573-83
Publication
First Author: Conduit SE
Year: 2017
Journal: Oncogene
Title: A compartmentalized phosphoinositide signaling axis at cilia is regulated by INPP5E to maintain cilia and promote Sonic Hedgehog medulloblastoma.
Volume: 36
Issue: 43
Pages: 5969-5984
Publication
First Author: Hwang GH
Year: 2024
Journal: Cancer Res
Title: A Benzarone Derivative Inhibits EYA to Suppress Tumor Growth in SHH Medulloblastoma.
Volume: 84
Issue: 6
Pages: 872-886
Publication
First Author: Geng R
Year: 2017
Journal: Sci Rep
Title: Modeling and Preventing Progressive Hearing Loss in Usher Syndrome III.
Volume: 7
Issue: 1
Pages: 13480
Publication
First Author: Bering T
Year: 2017
Journal: J Neurochem
Title: Deleting the Arntl clock gene in the granular layer of the mouse cerebellum: impact on the molecular circadian clockwork.
Volume: 142
Issue: 6
Pages: 841-856
Publication
First Author: Reddy NC
Year: 2021
Journal: Nat Commun
Title: CHARGE syndrome protein CHD7 regulates epigenomic activation of enhancers in granule cell precursors and gyrification of the cerebellum.
Volume: 12
Issue: 1
Pages: 5702
Strain
Attribute String: endonuclease-mediated mutation, mutant stock
Genotype
Symbol: Abl1/Abl1 Abl2/Abl2 Tg(Atoh1-cre)1Bfri/?
Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6J * CBA
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(Atoh1-sb11)1Mtay/? TgTn(sb-T2/Onc3)12740Njen/?
Background: involves: C3H * C57BL/6J * ICR
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(Camk2a-SNCA*)2Mgsp/? Del(6Snca)1Slab/Del(6Snca)1Slab
Background: B6JOlaHsd.Cg-Tg(Camk2a-SNCA*)2Mgsp
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Rr387/Rr387 Rr388/Rr388 Rr397/Rr397
Background: Not Specified
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Chd7/Chd7 Tg(Atoh1-cre)1Bfri/?
Background: involves: C57BL/6 * C57BL/6J * C57BL/6N * CBA
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Chd7/Chd7 Tg(Atoh1-cre)1Bfri/?
Background: involves: C57BL/6 * C57BL/6N * CBA
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Chd7/Chd7<+> Tg(Atoh1-cre)1Bfri/?
Background: involves: C57BL/6 * C57BL/6J * C57BL/6N * CBA
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Atoh1-cre)1Mhos/?
Background: involves: 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(Atoh1-cre)1Bfri/? Wwtr1/Wwtr1 Yap1/Yap1
Background: involves: 129S/SvEv * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Atoh1-cre)1Bfri/? Ythdf1/Ythdf1
Background: involves: 129X1/SvJ * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Eed/Eed Tg(Atoh1-cre)1Bfri/?
Background: involves: C57BL/6 * C57BL/6N * CBA
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Chd7/Chd7<+> Tg(Atoh1-cre)1Bfri/?
Background: involves: C57BL/6 * C57BL/6N * CBA
Zygosity: cn
Has Mutant Allele: true
Publication  
First Author: Marney CB
Year: 2022
Journal: Cells
Title: A Unique Spectrum of Spontaneous Tumors in Dino Knockout Mice Identifies Tissue-Specific Requirements for Tumor Suppression.
Volume: 11
Issue: 11
Publication
First Author: Lee EY
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Hedgehog pathway-regulated gene networks in cerebellum development and tumorigenesis.
Volume: 107
Issue: 21
Pages: 9736-41
Publication  
First Author: Garcia-Reitboeck P
Year: 2013
Journal: Exp Neurol
Title: Endogenous alpha-synuclein influences the number of dopaminergic neurons in mouse substantia nigra.
Volume: 248
Pages: 541-5
Publication  
First Author: Chadchankar H
Year: 2011
Journal: Brain Res
Title: Decreased reuptake of dopamine in the dorsal striatum in the absence of α-synuclein.
Volume: 1382
Pages: 37-44
Publication
First Author: Pelkonen A
Year: 2011
Journal: Neurosci Lett
Title: Neuromuscular pathology in mice lacking alpha-synuclein.
Volume: 487
Issue: 3
Pages: 350-3
Publication
First Author: Sharon R
Year: 2003
Journal: J Biol Chem
Title: Altered fatty acid composition of dopaminergic neurons expressing alpha-synuclein and human brains with alpha-synucleinopathies.
Volume: 278
Issue: 50
Pages: 49874-81
Publication
First Author: Gaffield MA
Year: 2019
Journal: Neuron
Title: Conversion of Graded Presynaptic Climbing Fiber Activity into Graded Postsynaptic Ca2+ Signals by Purkinje Cell Dendrites.
Volume: 102
Issue: 4
Pages: 762-769.e4
Publication
First Author: Bellucci A
Year: 2011
Journal: PLoS One
Title: Redistribution of DAT/α-synuclein complexes visualized by "in situ" proximity ligation assay in transgenic mice modelling early Parkinson's disease.
Volume: 6
Issue: 12
Pages: e27959
Publication
First Author: Nicot S
Year: 2019
Journal: FASEB J
Title: Seeded propagation of α-synuclein aggregation in mouse brain using protein misfolding cyclic amplification.
Volume: 33
Issue: 11
Pages: 12073-12086
Publication
First Author: Ben-Moshe H
Year: 2020
Journal: J Mol Neurosci
Title: ApoE4 Exacerbates Hippocampal Pathology Following Acute Brain Penetration Injury in Female Mice.
Volume: 70
Issue: 1
Pages: 32-44
Publication  
First Author: Bar R
Year: 2018
Journal: Alzheimers Dement (Amst)
Title: The effects of apolipoprotein E genotype, α-synuclein deficiency, and sex on brain synaptic and Alzheimer's disease-related pathology.
Volume: 10
Pages: 1-11
Publication
First Author: Zaltieri M
Year: 2015
Journal: J Cell Sci
Title: α-synuclein and synapsin III cooperatively regulate synaptic function in dopamine neurons.
Volume: 128
Issue: 13
Pages: 2231-43
Publication
First Author: Simonovitch S
Year: 2019
Journal: J Alzheimers Dis
Title: The Effects of APOE4 on Mitochondrial Dynamics and Proteins in vivo.
Volume: 70
Issue: 3
Pages: 861-875
Publication  
First Author: Faustini G
Year: 2020
Journal: Neurobiol Dis
Title: Alpha-synuclein/synapsin III pathological interplay boosts the motor response to methylphenidate.
Volume: 138
Pages: 104789
Publication
First Author: Lospinoso Severini L
Year: 2024
Journal: Cell Death Differ
Title: SALL4 is a CRL3(REN/KCTD11) substrate that drives Sonic Hedgehog-dependent medulloblastoma.
Volume: 31
Issue: 2
Pages: 170-187
Publication  
First Author: Gurdziel K
Year: 2016
Journal: BMC Dev Biol
Title: Computational prediction and experimental validation of novel Hedgehog-responsive enhancers linked to genes of the Hedgehog pathway.
Volume: 16
Pages: 4
Publication
First Author: Jun S
Year: 2023
Journal: Cell Rep
Title: Organization of Purkinje cell development by neuronal MEGF11 in cerebellar granule cells.
Volume: 42
Issue: 9
Pages: 113137
Publication
First Author: Boussaty EC
Year: 2024
Journal: PLoS Genet
Title: Altered Fhod3 expression involved in progressive high-frequency hearing loss via dysregulation of actin polymerization stoichiometry in the cuticular plate.
Volume: 20
Issue: 3
Pages: e1011211
Publication
First Author: Morrissy AS
Year: 2016
Journal: Nature
Title: Divergent clonal selection dominates medulloblastoma at recurrence.
Volume: 529
Issue: 7586
Pages: 351-7
Publication
First Author: Ledvin L
Year: 2023
Journal: Dev Cell
Title: The anaphase-promoting complex controls a ubiquitination-phosphoprotein axis in chromatin during neurodevelopment.
Volume: 58
Issue: 23
Pages: 2666-2683.e9
Publication
First Author: Badodi S
Year: 2021
Journal: Nat Commun
Title: Inositol treatment inhibits medulloblastoma through suppression of epigenetic-driven metabolic adaptation.
Volume: 12
Issue: 1
Pages: 2148
Publication
First Author: Tech K
Year: 2017
Journal: Cancer Res
Title: Pyruvate Kinase Inhibits Proliferation during Postnatal Cerebellar Neurogenesis and Suppresses Medulloblastoma Formation.
Volume: 77
Issue: 12
Pages: 3217-3230
Allele
Name: atonal bHLH transcription factor 1; targeted mutation 1, Bernd Fritzsch
Allele Type: Targeted
Attribute String: Epitope tag, Inserted expressed sequence, Null/knockout, Reporter
Genotype
Symbol: Del(6Snca)1Slab/Del(6Snca)1Slab Tg(Th-SNCA*)1Mgsp/?
Background: involves: C57BL/6J * C57BL/6JOlaHsd * CBA/Ca
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(ACTFLPe)9205Dym/? Tg(Atoh1-cre)1Bfri/?
Background: involves: 129S6/SvEvTac * C57BL/6 * CBA * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(Atoh1-sb11)1Mtay/? TgTn(sb-T2/Onc3)12740Njen/? Trp53/Trp53
Background: involves: 129S2/SvPas * C3H * C57BL/6J * ICR
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Capzb/Capzb Tg(Atoh1-cre)1Bfri/?
Background: involves: C57BL/6N * CBA * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Pkhd1l1/Pkhd1l1 Tg(Atoh1-cre)1Bfri/?
Background: involves: 129S4/SvJaeSor * C57BL/6 * C57BL/6N * CBA
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Hbs1l/Hbs1l Tg(Atoh1-cre)1Bfri/?
Background: involves: 129S4/SvJaeSor * C57BL/6NTac * CBA
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Chd7/Chd7 Tg(Atoh1-cre)1Bfri/? Tg(Nes-Reln)#Cur/?
Background: involves: C57BL/6 * C57BL/6J * C57BL/6N * CBA * FVB
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Chd7/Chd7 Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Atoh1-cre)1Bfri/?
Background: involves: 129 * C57BL/6 * C57BL/6NCrl * CBA
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Brd4/Brd4 Tg(Atoh1-cre)1Bfri/?
Background: involves: C57BL/6 * C57BL/6N * CBA
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Atoh1/Atoh1<+> Gt(ROSA)26Sor/Gt(ROSA)26Sor<+>
Background: involves: 129S4/SvJaeSor * 129S6/SvEvTac
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Atoh1/Atoh1<+> Gt(ROSA)26Sor/Gt(ROSA)26Sor<+>
Background: involves: 129S6/SvEvTac * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Atoh1-cre)1Bfri/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(CMV-Atoh1,-lacZ)1Kag/? Tg(Nes-cre)1Kag/?
Background: Not Specified
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Atoh1-cre)1Bfri/?
Background: involves: 129S4/SvJaeSor * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Atoh1/Atoh1<+> Gt(ROSA)26Sor/Gt(ROSA)26Sor<+>
Background: involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6J
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Atoh1-cre/ERT2)45Fmr/?
Background: involves: 129S6/SvEvTac * C57BL/6NCrl
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Atoh1-cre/ERT2)45Fmr/?
Background: involves: 129S6/SvEvTac * C57BL/6NCrl * CD-1
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Atoh1-cre)1Bfri/?
Background: involves: 129 * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Atoh1/Atoh1<+> Gt(ROSA)26Sor/Gt(ROSA)26Sor<+>
Background: involves: 129S6/SvEvTac * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Atoh1-cre)1Bfri/?
Background: involves: C57BL/6J * CBA
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Briggs KJ
Year: 2008
Journal: Genes Dev
Title: Cooperation between the Hic1 and Ptch1 tumor suppressors in medulloblastoma.
Volume: 22
Issue: 6
Pages: 770-85
Publication
First Author: Shi F
Year: 2014
Journal: J Neurosci
Title: β-Catenin is required for hair-cell differentiation in the cochlea.
Volume: 34
Issue: 19
Pages: 6470-9
Publication
First Author: Yu Y
Year: 2010
Journal: J Neurosci
Title: In vivo proliferation of postmitotic cochlear supporting cells by acute ablation of the retinoblastoma protein in neonatal mice.
Volume: 30
Issue: 17
Pages: 5927-36
Publication  
First Author: Verhaegen ME
Year: 2022
Journal: J Clin Invest
Title: Direct cellular reprogramming enables development of viral T antigen-driven Merkel cell carcinoma in mice.
Volume: 132
Issue: 7
Publication
First Author: Logan GJ
Year: 2018
Journal: Dev Biol
Title: Notch pathway signaling in the skin antagonizes Merkel cell development.
Volume: 434
Issue: 2
Pages: 207-214
Publication  
First Author: Elliott KL
Year: 2023
Journal: Neurosci Lett
Title: Ptf1a expression is necessary for correct targeting of spiral ganglion neurons within the cochlear nuclei.
Volume: 806
Pages: 137244
Publication  
First Author: Gu Y
Year: 2023
Journal: Hear Res
Title: Generation of p27icreER transgenic mice: A tool for inducible gene expression in supporting cells in the cochlea.
Volume: 431
Pages: 108727
Publication  
First Author: Matern MS
Year: 2020
Journal: Development
Title: GFI1 functions to repress neuronal gene expression in the developing inner ear hair cells.
Volume: 147
Issue: 17
Publication  
First Author: Cox BC
Year: 2014
Journal: Sci Rep
Title: Generation of Atoh1-rtTA transgenic mice: a tool for inducible gene expression in hair cells of the inner ear.
Volume: 4
Pages: 6885
Publication
First Author: Li J
Year: 2020
Journal: Nucleic Acids Res
Title: Dynamic changes in cis-regulatory occupancy by Six1 and its cooperative interactions with distinct cofactors drive lineage-specific gene expression programs during progressive differentiation of the auditory sensory epithelium.
Volume: 48
Issue: 6
Pages: 2880-2896
Publication
First Author: Bjerknes M
Year: 2006
Journal: Dev Biol
Title: Neurogenin 3 and the enteroendocrine cell lineage in the adult mouse small intestinal epithelium.
Volume: 300
Issue: 2
Pages: 722-35
Publication  
First Author: Veithen M
Year: 2023
Journal: Cells
Title: Sox9 Inhibits Cochlear Hair Cell Fate by Upregulating Hey1 and HeyL Antagonists of Atoh1.
Volume: 12
Issue: 17
Publication
First Author: Noah TK
Year: 2013
Journal: Gastroenterology
Title: SPDEF functions as a colorectal tumor suppressor by inhibiting β-catenin activity.
Volume: 144
Issue: 5
Pages: 1012-1023.e6
Publication  
First Author: Masuda M
Year: 2011
Journal: Neuroscience
Title: Regulation of POU4F3 gene expression in hair cells by 5' DNA in mice.
Volume: 197
Pages: 48-64
Publication
First Author: Tamagawa Y
Year: 2012
Journal: Lab Invest
Title: Notch signaling pathway and Cdx2 expression in the development of Barrett's esophagus.
Volume: 92
Issue: 6
Pages: 896-909
Publication
First Author: Badenes M
Year: 2017
Journal: BMC Cancer
Title: Delta-like 4/Notch signaling promotes Apc Min/+ tumor initiation through angiogenic and non-angiogenic related mechanisms.
Volume: 17
Issue: 1
Pages: 50
Publication
First Author: Park JY
Year: 2016
Journal: Development
Title: The apical complex protein Pals1 is required to maintain cerebellar progenitor cells in a proliferative state.
Volume: 143
Issue: 1
Pages: 133-46
Publication
First Author: Wu X
Year: 2012
Journal: Nature
Title: Clonal selection drives genetic divergence of metastatic medulloblastoma.
Volume: 482
Issue: 7386
Pages: 529-33
Publication
First Author: Cookman CJ
Year: 2015
Journal: Endocrinology
Title: Estrogen Receptor-β Up-Regulates IGF1R Expression and Activity to Inhibit Apoptosis and Increase Growth of Medulloblastoma.
Volume: 156
Issue: 7
Pages: 2395-408
Publication
First Author: Du F
Year: 2019
Journal: Clin Cancer Res
Title: Leukotriene Synthesis Is Critical for Medulloblastoma Progression.
Volume: 25
Issue: 21
Pages: 6475-6486
Publication
First Author: Yang Y
Year: 2024
Journal: Cancer Cell
Title: Thyroid hormone suppresses medulloblastoma progression through promoting terminal differentiation of tumor cells.
Volume: 42
Issue: 8
Pages: 1434-1449.e5
Publication
First Author: Levi O
Year: 2003
Journal: Neurobiol Dis
Title: ApoE4 impairs hippocampal plasticity isoform-specifically and blocks the environmental stimulation of synaptogenesis and memory.
Volume: 13
Issue: 3
Pages: 273-82
Publication
First Author: Wilson SL
Year: 2011
Journal: Cerebellum
Title: Spatially restricted and developmentally dynamic expression of engrailed genes in multiple cerebellar cell types.
Volume: 10
Issue: 3
Pages: 356-72
Publication
First Author: Dey J
Year: 2013
Journal: Cancer Res
Title: MyoD is a tumor suppressor gene in medulloblastoma.
Volume: 73
Issue: 22
Pages: 6828-37
Publication    
First Author: Bassett EA
Year: 2016
Journal: Elife
Title: Norrin/Frizzled4 signalling in the preneoplastic niche blocks medulloblastoma initiation.
Volume: 5
Publication
First Author: Kutscher LM
Year: 2020
Journal: Genes Dev
Title: Functional loss of a noncanonical BCOR-PRC1.1 complex accelerates SHH-driven medulloblastoma formation.
Volume: 34
Issue: 17-18
Pages: 1161-1176
Publication
First Author: Cheng Y
Year: 2020
Journal: Cell Rep
Title: NeuroD1 Dictates Tumor Cell Differentiation in Medulloblastoma.
Volume: 31
Issue: 12
Pages: 107782
Publication
First Author: Raleigh DR
Year: 2018
Journal: Mol Cell
Title: Cilia-Associated Oxysterols Activate Smoothened.
Volume: 72
Issue: 2
Pages: 316-327.e5
Publication
First Author: Jiang D
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Full p53 transcriptional activation potential is dispensable for tumor suppression in diverse lineages.
Volume: 108
Issue: 41
Pages: 17123-8
Publication
First Author: Faria CC
Year: 2015
Journal: Cancer Res
Title: Foretinib is effective therapy for metastatic sonic hedgehog medulloblastoma.
Volume: 75
Issue: 1
Pages: 134-46
Publication  
First Author: Wijayatunge R
Year: 2018
Journal: Mol Cell Neurosci
Title: The histone demethylase Kdm6b regulates a mature gene expression program in differentiating cerebellar granule neurons.
Volume: 87
Pages: 4-17
Publication  
First Author: Ocasio JK
Year: 2019
Journal: Development
Title: GSK-3 modulates SHH-driven proliferation in postnatal cerebellar neurogenesis and medulloblastoma.
Volume: 146
Issue: 20
Publication
First Author: Frick A
Year: 2012
Journal: Glia
Title: Proper cerebellar development requires expression of β1-integrin in Bergmann glia, but not in granule neurons.
Volume: 60
Issue: 5
Pages: 820-32
Publication
First Author: Crowther AJ
Year: 2016
Journal: Cancer Res
Title: Radiation Sensitivity in a Preclinical Mouse Model of Medulloblastoma Relies on the Function of the Intrinsic Apoptotic Pathway.
Volume: 76
Issue: 11
Pages: 3211-23
Publication
First Author: Vashi N
Year: 2021
Journal: Hum Mol Genet
Title: Aberrant lung lipids cause respiratory impairment in a Mecp2-deficient mouse model of Rett syndrome.
Volume: 30
Issue: 22
Pages: 2161-2176
Publication
First Author: Ravussin A
Year: 2018
Journal: Cell Rep
Title: Loss of Nucleobindin-2 Causes Insulin Resistance in Obesity without Impacting Satiety or Adiposity.
Volume: 24
Issue: 5
Pages: 1085-1092.e6
Publication
First Author: Kropp M
Year: 2012
Journal: Dev Dyn
Title: The expression profile of the tumor suppressor gene Lzts1 suggests a role in neuronal development.
Volume: 241
Issue: 5
Pages: 984-94
Publication
First Author: Kawamura A
Year: 2021
Journal: Cell Rep
Title: The autism-associated protein CHD8 is required for cerebellar development and motor function.
Volume: 35
Issue: 1
Pages: 108932