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Search results 1701 to 1800 out of 1965 for Dnmt1

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Type Details Score
Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
21731673 | J:174767
First Author: Tang F
Year: 2011
Journal: PLoS One
Title: Deterministic and stochastic allele specific gene expression in single mouse blastomeres.
Volume: 6
Issue: 6
Pages: e21208
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Publication
20412781 | J:140465
First Author: Guo G
Year: 2010
Journal: Dev Cell
Title: Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.
Volume: 18
Issue: 4
Pages: 675-85
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Publication
20059953 | J:156017
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
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Publication
- | J:72245
       
First Author: GOA curators, MGI curators
Year: 2001
Title: Gene Ontology annotation based on Enzyme Commission mapping
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
17967808 | J:152068
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
15618518 | J:91257
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
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Publication
24952961 | J:215487
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
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Publication
14681479 | J:122989
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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HT Experiment
E-GEOD-14216 | Transcription profiling of mouse wild type vs Dnmt1 hypomethylated forebrain
Series Id: GSE14216
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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HT Experiment
GSE19367 | Gene expression changes in mouse forebrain deficient in Dnmt1 and Dnmt3a
Series Id: E-GEOD-19367
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: GEO
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Publication
28542810 | J:244809
First Author: Wang S
Year: 2017
Journal: FEBS Lett
Title: DNMT1 cooperates with MBD4 to inhibit the expression of Glucocorticoid-induced TNFR-related protein in human T cells.
Volume: 591
Issue: 13
Pages: 1929-1939
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Publication
32999320 | J:296393
First Author: Chen YT
Year: 2020
Journal: Sci Rep
Title: NT5C2 methylation regulatory interplay between DNMT1 and insulin receptor in type 2 diabetes.
Volume: 10
Issue: 1
Pages: 16087
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Publication
39107797 | J:352927
First Author: Tsiami F
Year: 2024
Journal: Acta Neuropathol Commun
Title: Genome-wide CRISPR-Cas9 knockout screens identify DNMT1 as a druggable dependency in sonic hedgehog medulloblastoma.
Volume: 12
Issue: 1
Pages: 125
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HT Experiment
GSE129177 | DNMT1 is required for proximal-distal patterning of the lung endoderm and restraining alveolar type 2 cell fate
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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ncRNA Gene
MGP_CAROLIEiJ_G0004362 | -
Type: ncRNA_gene
Organism: Mus caroli
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ncRNA Gene
MGP_129S1SvImJ_G0004817 | -
Type: ncRNA_gene
Organism: mouse, laboratory
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ncRNA Gene
MGP_AJ_G0004798 | -
Type: ncRNA_gene
Organism: mouse, laboratory
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ncRNA Gene
MGP_AKRJ_G0004777 | -
Type: ncRNA_gene
Organism: mouse, laboratory
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ncRNA Gene
MGP_BALBcJ_G0004780 | -
Type: ncRNA_gene
Organism: mouse, laboratory
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ncRNA Gene
MGP_C3HHeJ_G0004728 | -
Type: ncRNA_gene
Organism: mouse, laboratory
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lncRNA Gene
MGI_C57BL6J_5579231 | -
Type: lncRNA_gene
Organism: mouse, laboratory
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ncRNA Gene
MGP_C57BL6NJ_G0004930 | -
Type: ncRNA_gene
Organism: mouse, laboratory
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ncRNA Gene
MGP_CASTEiJ_G0004684 | -
Type: ncRNA_gene
Organism: mouse, laboratory
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ncRNA Gene
MGP_CBAJ_G0004721 | -
Type: ncRNA_gene
Organism: mouse, laboratory
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ncRNA Gene
MGP_DBA2J_G0004739 | -
Type: ncRNA_gene
Organism: mouse, laboratory
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ncRNA Gene
MGP_FVBNJ_G0004759 | -
Type: ncRNA_gene
Organism: mouse, laboratory
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ncRNA Gene
MGP_LPJ_G0004818 | -
Type: ncRNA_gene
Organism: mouse, laboratory
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ncRNA Gene
MGP_NODShiLtJ_G0004744 | -
Type: ncRNA_gene
Organism: mouse, laboratory
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ncRNA Gene
MGP_NZOHlLtJ_G0004934 | -
Type: ncRNA_gene
Organism: mouse, laboratory
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ncRNA Gene
MGP_PWKPhJ_G0004636 | -
Type: ncRNA_gene
Organism: mouse, laboratory
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ncRNA Gene
MGP_WSBEiJ_G0004726 | -
Type: ncRNA_gene
Organism: mouse, laboratory
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ncRNA Gene
MGP_PahariEiJ_G0005912 | -
Type: ncRNA_gene
Organism: Mus pahari
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ncRNA Gene
MGP_SPRETEiJ_G0004563 | -
Type: ncRNA_gene
Organism: Mus spretus
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Interaction Experiment
Fuks F (2000)
Description: DNA methyltransferase Dnmt1 associates with histone deacetylase activity.
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Interaction Experiment
Sajedi E (2008)
Description: DNMT1 interacts with the developmental transcriptional repressor HESX1.
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Protein
P13864
Organism: Mus musculus/domesticus
Length: 1620  
Fragment?: false
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Interaction Experiment
Shamma A (2013)
Description: ATM mediates pRB function to control DNMT1 protein stability and DNA methylation
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Interaction Experiment
Liu X (2013)
Description: UHRF1 targets DNMT1 for DNA methylation through cooperative binding of hemi-methylated DNA and methylated H3K9.
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Interaction Experiment
Smets M (2017)
Description: DNMT1 mutations found in HSANIE patients affect interaction with UHRF1 and neuronal differentiation.
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Interaction Experiment
Nishiyama A (2020)
Description: Two distinct modes of DNMT1 recruitment ensure stable maintenance DNA methylation.
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Interaction Experiment
Gowher H (2005)
Description: De novo methylation of nucleosomal DNA by the mammalian Dnmt1 and Dnmt3A DNA methyltransferases.
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Interaction Experiment
Frauer C (2011)
Description: Different binding properties and function of CXXC zinc finger domains in Dnmt1 and Tet1.
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Publication
14734556 | -
First Author: Liu Z
Year: 2004
Journal: J Biol Chem
Title: RGS6 interacts with DMAP1 and DNMT1 and inhibits DMAP1 transcriptional repressor activity.
Volume: 279
Issue: 14
Pages: 14120-8
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Publication
32580634 | J:318559
First Author: Strand KA
Year: 2020
Journal: Arterioscler Thromb Vasc Biol
Title: High Throughput Screen Identifies the DNMT1 (DNA Methyltransferase-1) Inhibitor, 5-Azacytidine, as a Potent Inducer of PTEN (Phosphatase and Tensin Homolog): Central Role for PTEN in 5-Azacytidine Protection Against Pathological Vascular Remodeling.
Volume: 40
Issue: 8
Pages: 1854-1869
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Protein
P13864-2
Organism: Mus musculus/domesticus
Length: 1502  
Fragment?: false
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DO Term
DOID:0050968 | autosomal dominant cerebellar ataxia, deafness and narcolepsy
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HT Experiment
GSE81191 | Gene expression profile of Dnmt1 flox/flox, Dnmt3a flox/flox, Dnmt3b flox/flox, cre negative (Wild type) and Dnmt1 flox/flox, Dnmt3a flox/flox, Dnmt3b flox/flox, Rx-cre (Triple mutant) murine retina transcriptomes
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE121086 | Comparison of DNA methyltransferase-1 (Dnmt1) deleted urogenital sinus epithelium compared to wildtype urogenital sinus epithelium
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Allele
Dnmt1<tm1Smoc> | MGI:7289377
Name: DNA methyltransferase 1; targeted mutation 1, Shanghai Model Organisms Center
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Publication
10888886 | -
First Author: Robertson KD
Year: 2000
Journal: Nat Genet
Title: DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters.
Volume: 25
Issue: 3
Pages: 338-42
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Publication
21311766 | -
First Author: Frauer C
Year: 2011
Journal: PLoS One
Title: Different binding properties and function of CXXC zinc finger domains in Dnmt1 and Tet1.
Volume: 6
Issue: 2
Pages: e16627
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Publication
16026162 | -
First Author: Gowher H
Year: 2005
Journal: Biochemistry
Title: De novo methylation of nucleosomal DNA by the mammalian Dnmt1 and Dnmt3A DNA methyltransferases.
Volume: 44
Issue: 29
Pages: 9899-904
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Publication
28334952 | -
First Author: Smets M
Year: 2017
Journal: Hum Mol Genet
Title: DNMT1 mutations found in HSANIE patients affect interaction with UHRF1 and neuronal differentiation.
Volume: 26
Issue: 8
Pages: 1522-1534
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Publication
32144273 | -
First Author: Nishiyama A
Year: 2020
Journal: Nat Commun
Title: Two distinct modes of DNMT1 recruitment ensure stable maintenance DNA methylation.
Volume: 11
Issue: 1
Pages: 1222
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DO Term
DOID:0070158 | hereditary sensory neuropathy type 1E
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Publication
10947852 | -
First Author: Tatematsu KI
Year: 2000
Journal: Genes Cells
Title: MBD2-MBD3 complex binds to hemi-methylated DNA and forms a complex containing DNMT1 at the replication foci in late S phase.
Volume: 5
Issue: 8
Pages: 677-88
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Allele
Tg(Pdx1-DNMT1)#Ggu | MGI:6357900
Name: transgene insertion, Guoqiang Gu
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Publication
12616525 | -
First Author: Datta J
Year: 2003
Journal: J Cell Biochem
Title: Biochemical fractionation reveals association of DNA methyltransferase (Dnmt) 3b with Dnmt1 and that of Dnmt 3a with a histone H3 methyltransferase and Hdac1.
Volume: 88
Issue: 5
Pages: 855-64
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Allele
Tg(Dnmt1-EGFP)CJ101Gsat | MGI:4846999
Name: transgene insertion CJ101, GENSAT Project at Rockefeller University
Allele Type: Transgenic
Attribute String: Reporter
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Strain
MGI:6354739 | C57BL/6JSmoc-Dnmt1<tm1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, targeted mutation
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HT Experiment
GSE79018 | Functional characterization of DNA methylation in the oligodendrocyte lineage [RNASeq_Dnmt1cKO_OPC]
Series Id: E-GEOD-79018
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
1796789 | -
First Author: Corona M
Year: 1991
Journal: Anat Histol Embryol
Title: [The sensitive nerve endings of the clitoris of the sow (Sus scrofa domesticus)].
Volume: 20
Issue: 4
Pages: 369-77
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Protein Domain
IPR017198 | DNMT1-like
Type: Family
Description: This entry represents DNA (cytosine-5)-methyltransferase 1 (Dnmt1; ), which methylates CpG residues, with a preference for hemimethylated DNA. It is responsible for maintaining methylation patterns established in development. DNA methylation is coordinated with methylation of histones. Dnmt1 mediates transcriptional repression (silencing) by establishing a repressive transcription complex where the N terminus of Dnmt1 binds to HDAC2 (histone deacetylase-2) as well as to DMAP1 (Dnmt1-associated protein) []. LSH, which is related to the SNF2 chromatin-remodelling ATPases, is also required for efficient DNA methylation [].
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HT Experiment
GSE250370 | Disruption of DNA methylation-mediated cranial neural crest proliferation and differentiation causes orofacial clefts in mice
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Allele
Dnmt1<tm3Jae> | MGI:2657151
Name: DNA methyltransferase 1; targeted mutation 3, Rudolf Jaenisch
Allele Type: Targeted
Attribute String: Inserted expressed sequence
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Strain
MGI:5003626 | STOCK Tg(Dnmt1-EGFP)CJ101Gsat/Mmucd
Attribute String: mutant stock, transgenic
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Genotype
Genotype
Symbol: Dnmt1/Dnmt1
Background: involves: 129S4/SvJae * BALB/c
Zygosity: hm
Has Mutant Allele: true
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Protein Domain
IPR008468 | DMAP1
Type: Domain
Description: This entry represents a domain found in DNA methyltransferase 1-associated protein 1 (DMAP1). DNA methylation can contribute to transcriptional silencing through several transcriptionally repressive complexes, which include methyl-CpG binding domain proteins (MBDs) and histone deacetylases (HDACs). The chief enzyme that maintains mammalian DNA methylation, DNMT1, can also establish a repressive transcription complex. The non-catalytic N terminus of DNMT1 binds to HDAC2 and DMAP1, and can mediate transcriptional repression. DMAP1 has intrinsic transcription repressive activity, and binds to the transcriptional co-repressor TSG101. DMAP1 is targeted to replication foci through interaction with the far N terminus of DNMT1 throughout S phase, whereas HDAC2 joins DNMT1 and DMAP1 only during late S phase, providing a platform for how histones may become deacetylated in heterochromatin following replication [].
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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