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Search results 1701 to 1800 out of 2260 for Erbb2

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0.019s

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Type Details Score
Publication
22215620 | J:183719
First Author: Gabai VL
Year: 2012
Journal: Mol Cell Biol
Title: Heat shock transcription factor Hsf1 is involved in tumor progression via regulation of hypoxia-inducible factor 1 and RNA-binding protein HuR.
Volume: 32
Issue: 5
Pages: 929-40
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Publication
27820834 | J:251151
First Author: Chen X
Year: 2016
Journal: PLoS One
Title: CCL2/CCR2 Regulates the Tumor Microenvironment in HER-2/neu-Driven Mammary Carcinomas in Mice.
Volume: 11
Issue: 11
Pages: e0165595
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Publication
19056892 | J:142037
First Author: Miranda-Carboni GA
Year: 2008
Journal: Genes Dev
Title: A functional link between Wnt signaling and SKP2-independent p27 turnover in mammary tumors.
Volume: 22
Issue: 22
Pages: 3121-34
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Publication
25347743 | J:224258
First Author: Sangrar W
Year: 2015
Journal: Oncogene
Title: Amplified Ras-MAPK signal states correlate with accelerated EGFR internalization, cytostasis and delayed HER2 tumor onset in Fer-deficient model systems.
Volume: 34
Issue: 31
Pages: 4109-17
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Publication
17347513 | J:120339
First Author: Bentires-Alj M
Year: 2007
Journal: Cancer Res
Title: Protein-tyrosine phosphatase 1B is required for HER2/Neu-induced breast cancer.
Volume: 67
Issue: 6
Pages: 2420-4
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Publication
29408223 | J:320876
 
First Author: Oh S
Year: 2018
Journal: Cell Signal
Title: Egr-1 is required for neu/HER2-induced mammary tumors.
Volume: 45
Pages: 102-109
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Publication
33196707 | J:310572
First Author: Petrova SC
Year: 2020
Journal: Oncotarget
Title: Regulation of breast cancer oncogenesis by the cell of origin's differentiation state.
Volume: 11
Issue: 43
Pages: 3832-3848
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Publication
28276425 | J:244404
 
First Author: Ahn R
Year: 2017
Journal: Nat Commun
Title: The Shc1 adaptor simultaneously balances Stat1 and Stat3 activity to promote breast cancer immune suppression.
Volume: 8
Pages: 14638
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Publication
25023728 | J:214234
First Author: Yori JL
Year: 2014
Journal: Cancer Res
Title: Combined SFK/mTOR inhibition prevents rapamycin-induced feedback activation of AKT and elicits efficient tumor regression.
Volume: 74
Issue: 17
Pages: 4762-71
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Publication
37240357 | J:336142
 
First Author: Wu H
Year: 2023
Journal: Int J Mol Sci
Title: Dietary Supplementation of Inulin Contributes to the Prevention of Estrogen Receptor-Negative Mammary Cancer by Alteration of Gut Microbial Communities and Epigenetic Regulations.
Volume: 24
Issue: 10
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Publication
25267403 | J:309639
First Author: Dong Y
Year: 2014
Journal: Cell Res
Title: Taspase1 cleaves MLL1 to activate cyclin E for HER2/neu breast tumorigenesis.
Volume: 24
Issue: 11
Pages: 1354-66
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Publication
33780491 | J:304390
First Author: Sheng G
Year: 2021
Journal: PLoS One
Title: Reduction of fibrosis and immune suppressive cells in ErbB2-dependent tumorigenesis by an LXR agonist.
Volume: 16
Issue: 3
Pages: e0248996
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Publication
27797378 | J:241261
First Author: Sizemore GM
Year: 2017
Journal: Oncogene
Title: Stromal PTEN inhibits the expansion of mammary epithelial stem cells through Jagged-1.
Volume: 36
Issue: 16
Pages: 2297-2308
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Publication
27902734 | J:250910
First Author: Grosset AA
Year: 2016
Journal: PLoS One
Title: Galectin-7 Expression Potentiates HER-2-Positive Phenotype in Breast Cancer.
Volume: 11
Issue: 11
Pages: e0166731
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Publication
20924104 | J:165565
First Author: Ursini-Siegel J
Year: 2010
Journal: Cancer Res
Title: Receptor tyrosine kinase signaling favors a protumorigenic state in breast cancer cells by inhibiting the adaptive immune response.
Volume: 70
Issue: 20
Pages: 7776-87
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Publication
38081972 | J:343425
First Author: Andreani C
Year: 2023
Journal: Sci Rep
Title: SIRT6 promotes metastasis and relapse in HER2-positive breast cancer.
Volume: 13
Issue: 1
Pages: 22000
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Publication
36656864 | J:333483
First Author: Itah Z
Year: 2023
Journal: Proc Natl Acad Sci U S A
Title: HER2-driven breast cancer suppression by the JNK signaling pathway.
Volume: 120
Issue: 4
Pages: e2218373120
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Publication
28892049 | J:254258
First Author: Rowson-Hodel AR
Year: 2018
Journal: Oncogene
Title: Membrane Mucin Muc4 promotes blood cell association with tumor cells and mediates efficient metastasis in a mouse model of breast cancer.
Volume: 37
Issue: 2
Pages: 197-207
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Publication
15126356 | J:89743
First Author: Hutchinson JN
Year: 2004
Journal: Cancer Res
Title: Activation of Akt-1 (PKB-alpha) can accelerate ErbB-2-mediated mammary tumorigenesis but suppresses tumor invasion.
Volume: 64
Issue: 9
Pages: 3171-8
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Publication
23026490 | J:291262
First Author: MacLennan MB
Year: 2013
Journal: J Nutr Biochem
Title: Mammary tumor development is directly inhibited by lifelong n-3 polyunsaturated fatty acids.
Volume: 24
Issue: 1
Pages: 388-95
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Strain
MGI:5883856 | FVB-Tg(MMTV-ERBB2*)#Arbs
Attribute String: coisogenic, mutant strain, transgenic
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Strain
MGI:5883860 | FVB-Tg(MMTV-ERBB2*)#Arbs/Cnbc
Attribute String: coisogenic, mutant strain, transgenic
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Publication
19364815 | J:149905
First Author: Pedersen K
Year: 2009
Journal: Mol Cell Biol
Title: A naturally occurring HER2 carboxy-terminal fragment promotes mammary tumor growth and metastasis.
Volume: 29
Issue: 12
Pages: 3319-31
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Genotype
Genotype
Symbol: Tg(MMTV-ERBB3)1Slg/? Tg(MMTVneu)202Mul/?
Background: involves: FVB
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Etv4/Etv4 Tg(MMTVneu)202Mul/Tg(MMTVneu)202Mul
Background: involves: FVB/N
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Erbb2/Erbb2 Tg(Ckmm-cre)5Khn/?
Background: involves: 129S1/Sv * 129X1/SvJ * BALB/c * FVB
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ccnd1/Ccnd1 Tg(MMTV-Erbb2)NK1Mul/?
Background: involves: 129S4/SvJae * C57BL/6 * FVB/N
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Erbb2/Erbb2 Myl2/Myl2<+>
Background: involves: 129P2/OlaHsd * 129S4/SvJae
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(CAG-Has2)99Nita/? Tg(MMTVneu)202Mul/?
Background: FVB.Cg-Tg(CAG-Has2)99Nita Tg(MMTVneu)202Mul
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Akt3/Akt3 Tg(MMTV-Erbb2)NK1Mul/Tg(MMTV-Erbb2)NK1Mul
Background: involves: 129 * C57BL/6 * FVB/N
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pik3cb/Pik3cb Tg(MMTVneu)202Mul/?
Background: involves: 129/Sv * 129P2/OlaHsd * BALB/c * C57BL/6J * FVB/N
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pten/Pten Tg(MMTVneu)202Mul/? Tg(S100a4-cre)1Gle/?
Background: involves: FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ccnd1/Ccnd1 Tg(MMTV-Erbb2)NK1Mul/?
Background: involves: 129S4/SvJae * C57BL/6 * FVB/N
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Erbb2/Erbb2<+> Pten/Pten<+> Tg(MMTV-cre)7Mul/?
Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Erbb2/Erbb2<+> Pten/Pten Tg(MMTV-cre)7Mul/?
Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ccnd1/Ccnd1<+> Tg(MMTVneu)202Mul/? Tg(tetO-Ccnd1*T286A,-luc)11233Kuw/?
Background: involves: 129S2/SvPas * FVB/N
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ccnd1/Ccnd1<+> Tg(MMTVneu)202Mul/? Tg(tetO-Ccnd1*T286A,-luc)10897Kuw/?
Background: involves: 129S2/SvPas * FVB/N
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ccnd1/Ccnd1 Tg(MMTVneu)202Mul/? Tg(tetO-Ccnd1*T286A,-luc)11233Kuw/?
Background: involves: 129S2/SvPas * FVB/N
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ccnd1/Ccnd1 Tg(MMTVneu)202Mul/? Tg(tetO-Ccnd1*T286A,-luc)10897Kuw/?
Background: involves: 129S2/SvPas * FVB/N
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ccnd1/Ccnd1 Tg(MMTVneu)202Mul/?
Background: involves: 129S2/SvPas * FVB/N
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(MMTV-ERBB2*)#Arbs/?
Background: FVB-Tg(MMTV-ERBB2*)#Arbs
Zygosity: ot
Has Mutant Allele: true
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Protein Coding Gene
MGI:1345147 | Akt3
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:97376 | Nras
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:96680 | Kras
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:104874 | Akt2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q9WUA6
Organism: Mus musculus/domesticus
Length: 479  
Fragment?: false
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Protein
Q60823
Organism: Mus musculus/domesticus
Length: 481  
Fragment?: false
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Protein
Q61411
Organism: Mus musculus/domesticus
Length: 189  
Fragment?: false
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Protein
P32883
Organism: Mus musculus/domesticus
Length: 189  
Fragment?: false
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Protein
P08556
Organism: Mus musculus/domesticus
Length: 189  
Fragment?: false
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Publication
23125191 | J:194123
First Author: Sukhanova A
Year: 2013
Journal: Cancer Discov
Title: Targeting C4-demethylating genes in the cholesterol pathway sensitizes cancer cells to EGF receptor inhibitors via increased EGF receptor degradation.
Volume: 3
Issue: 1
Pages: 96-111
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Publication
27207671 | J:232780
First Author: Tao Y
Year: 2016
Journal: Carcinogenesis
Title: Hsp70 exerts oncogenic activity in the Apc mutant Min mouse model.
Volume: 37
Issue: 7
Pages: 731-739
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Publication
19690388 | J:152703
First Author: Lee D
Year: 2009
Journal: J Clin Invest
Title: Tumor-specific apoptosis caused by deletion of the ERBB3 pseudo-kinase in mouse intestinal epithelium.
Volume: 119
Issue: 9
Pages: 2702-13
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Publication
25107366 | J:216308
First Author: Ruan YC
Year: 2014
Journal: J Cell Sci
Title: CFTR interacts with ZO-1 to regulate tight junction assembly and epithelial differentiation through the ZONAB pathway.
Volume: 127
Issue: Pt 20
Pages: 4396-408
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Publication
23348745 | J:194482
First Author: Yoshioka T
Year: 2013
Journal: J Clin Invest
Title: β4 Integrin signaling induces expansion of prostate tumor progenitors.
Volume: 123
Issue: 2
Pages: 682-99
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Publication
26786778 | J:236128
First Author: Vandekerckhove L
Year: 2016
Journal: Am J Physiol Endocrinol Metab
Title: Neuregulin-1 attenuates development of nephropathy in a type 1 diabetes mouse model with high cardiovascular risk.
Volume: 310
Issue: 7
Pages: E495-504
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Publication
20220087 | J:160056
First Author: Porzia A
Year: 2010
Journal: J Immunol
Title: Attenuation of PI3K/Akt-mediated tumorigenic signals through PTEN activation by DNA vaccine-induced anti-ErbB2 antibodies.
Volume: 184
Issue: 8
Pages: 4170-7
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Publication
14982856 | J:88435
First Author: Yang C
Year: 2004
Journal: Am J Pathol
Title: The role of the cyclin D1-dependent kinases in ErbB2-mediated breast cancer.
Volume: 164
Issue: 3
Pages: 1031-8
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Publication
25483966 | J:310371
First Author: Cicchini M
Year: 2014
Journal: Autophagy
Title: Autophagy regulator BECN1 suppresses mammary tumorigenesis driven by WNT1 activation and following parity.
Volume: 10
Issue: 11
Pages: 2036-52
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Publication
28636612 | J:244421
First Author: Ghidinelli M
Year: 2017
Journal: PLoS Biol
Title: Laminin 211 inhibits protein kinase A in Schwann cells to modulate neuregulin 1 type III-driven myelination.
Volume: 15
Issue: 6
Pages: e2001408
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Publication
25253740 | J:219681
First Author: Sinha VC
Year: 2015
Journal: Mol Cancer Res
Title: A p53/ARF-dependent anticancer barrier activates senescence and blocks tumorigenesis without impacting apoptosis.
Volume: 13
Issue: 2
Pages: 231-8
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Publication
20212127 | J:158688
First Author: Seshadri S
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Disrupted-in-Schizophrenia-1 expression is regulated by beta-site amyloid precursor protein cleaving enzyme-1-neuregulin cascade.
Volume: 107
Issue: 12
Pages: 5622-7
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Publication
15833803 | J:100313
First Author: Liu FF
Year: 2005
Journal: Am J Physiol Heart Circ Physiol
Title: Heterozygous knockout of neuregulin-1 gene in mice exacerbates doxorubicin-induced heart failure.
Volume: 289
Issue: 2
Pages: H660-6
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Publication
12951658 | J:104810
First Author: Schmucker J
Year: 2003
Journal: Glia
Title: erbB3 is dispensable for oligodendrocyte development in vitro and in vivo.
Volume: 44
Issue: 1
Pages: 67-75
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Publication
15470130 | J:132561
First Author: Stankovic K
Year: 2004
Journal: J Neurosci
Title: Survival of adult spiral ganglion neurons requires erbB receptor signaling in the inner ear.
Volume: 24
Issue: 40
Pages: 8651-61
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Publication
12054157 | J:112398
First Author: Usui M
Year: 2002
Journal: J Bone Miner Res
Title: Enhancing effect of Tob deficiency on bone formation is specific to bone morphogenetic protein-induced osteogenesis.
Volume: 17
Issue: 6
Pages: 1026-33
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Publication
23899604 | J:204096
First Author: Dahlhoff M
Year: 2013
Journal: Biochim Biophys Acta
Title: Increased activation of the epidermal growth factor receptor in transgenic mice overexpressing epigen causes peripheral neuropathy.
Volume: 1832
Issue: 12
Pages: 2068-76
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Publication
19738070 | J:152682
First Author: Cadieux C
Year: 2009
Journal: Cancer Res
Title: Mouse mammary tumor virus p75 and p110 CUX1 transgenic mice develop mammary tumors of various histologic types.
Volume: 69
Issue: 18
Pages: 7188-97
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Publication
28617998 | J:243919
First Author: Logan AM
Year: 2017
Journal: Glia
Title: Schwann cell-specific deletion of the endosomal PI 3-kinase Vps34 leads to delayed radial sorting of axons, arrested myelination, and abnormal ErbB2-ErbB3 tyrosine kinase signaling.
Volume: 65
Issue: 9
Pages: 1452-1470
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Publication
25596284 | J:219801
First Author: Song X
Year: 2015
Journal: Cancer Res
Title: ERBB3-independent activation of the PI3K pathway in EGFR-mutant lung adenocarcinomas.
Volume: 75
Issue: 6
Pages: 1035-45
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Publication
29410073 | J:261978
First Author: Hoesl C
Year: 2018
Journal: Biochim Biophys Acta
Title: The receptor tyrosine kinase ERBB4 is expressed in skin keratinocytes and influences epidermal proliferation.
Volume: 1862
Issue: 4
Pages: 958-966
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Publication
21482676 | J:172238
First Author: Cook RS
Year: 2011
Journal: Cancer Res
Title: ErbB3 ablation impairs PI3K/Akt-dependent mammary tumorigenesis.
Volume: 71
Issue: 11
Pages: 3941-51
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Publication
24550116 | J:234159
First Author: Huebner RJ
Year: 2014
Journal: Development
Title: Developmental stratification of the mammary epithelium occurs through symmetry-breaking vertical divisions of apically positioned luminal cells.
Volume: 141
Issue: 5
Pages: 1085-94
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Publication
26086099 | J:228680
First Author: Liu J
Year: 2015
Journal: Biochem Biophys Res Commun
Title: Trichostatin A suppresses lung adenocarcinoma development in Grg1 overexpressing transgenic mice.
Volume: 463
Issue: 4
Pages: 1230-6
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Publication
16007173 | J:101760
First Author: Kuns R
Year: 2005
Journal: Oncogene
Title: Protein 4.1B expression is induced in mammary epithelial cells during pregnancy and regulates their proliferation.
Volume: 24
Issue: 43
Pages: 6502-15
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Publication
20360002 | J:330122
First Author: Limpert AS
Year: 2010
Journal: J Biol Chem
Title: Axonal neuregulin 1 type III activates NF-kappaB in Schwann cells during myelin formation.
Volume: 285
Issue: 22
Pages: 16614-22
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Publication
33497358 | J:308268
 
First Author: Le TL
Year: 2021
Journal: J Clin Invest
Title: Dysregulation of the NRG1/ERBB pathway causes a developmental disorder with gastrointestinal dysmotility in humans.
Volume: 131
Issue: 6
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Publication
21826239 | J:176530
First Author: Young CD
Year: 2011
Journal: PLoS One
Title: Modulation of glucose transporter 1 (GLUT1) expression levels alters mouse mammary tumor cell growth in vitro and in vivo.
Volume: 6
Issue: 8
Pages: e23205
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Publication
28368009 | J:243702
 
First Author: Ueda O
Year: 2017
Journal: Sci Rep
Title: Entire CD3ε, δ, and γ humanized mouse to evaluate human CD3-mediated therapeutics.
Volume: 7
Pages: 45839
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Publication
21186272 | J:170361
First Author: Lemmens K
Year: 2011
Journal: Am J Physiol Heart Circ Physiol
Title: Activation of the neuregulin/ErbB system during physiological ventricular remodeling in pregnancy.
Volume: 300
Issue: 3
Pages: H931-42
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Publication
7816098 | J:22296
First Author: Jo SA
Year: 1995
Journal: Nature
Title: Neuregulins are concentrated at nerve-muscle synapses and activate ACh-receptor gene expression.
Volume: 373
Issue: 6510
Pages: 158-61
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Publication
9652750 | J:48026
First Author: Bafico A
Year: 1998
Journal: Oncogene
Title: Characterization of Wnt-1 and Wnt-2 induced growth alterations and signaling pathways in NIH3T3 fibroblasts.
Volume: 16
Issue: 21
Pages: 2819-25
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Publication
12055597 | J:77044
First Author: Wagner M
Year: 2002
Journal: Gastroenterology
Title: Transgenic overexpression of amphiregulin induces a mitogenic response selectively in pancreatic duct cells.
Volume: 122
Issue: 7
Pages: 1898-912
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Publication
17178859 | J:116753
First Author: Yang C
Year: 2006
Journal: Cancer Res
Title: Identification of cyclin D1- and estrogen-regulated genes contributing to breast carcinogenesis and progression.
Volume: 66
Issue: 24
Pages: 11649-58
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Publication
17440093 | J:120947
First Author: Wu Q
Year: 2007
Journal: Cancer Res
Title: Therapeutic effect of rapamycin on gallbladder cancer in a transgenic mouse model.
Volume: 67
Issue: 8
Pages: 3794-800
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Publication
18313710 | J:135632
First Author: Barrick CJ
Year: 2008
Journal: Toxicol Appl Pharmacol
Title: Chronic pharmacologic inhibition of EGFR leads to cardiac dysfunction in C57BL/6J mice.
Volume: 228
Issue: 3
Pages: 315-25
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Publication
18701486 | J:139144
First Author: Fehrenbacher N
Year: 2008
Journal: Cancer Res
Title: Sensitization to the lysosomal cell death pathway by oncogene-induced down-regulation of lysosome-associated membrane proteins 1 and 2.
Volume: 68
Issue: 16
Pages: 6623-33
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Publication
19349372 | J:147968
First Author: Liu M
Year: 2009
Journal: Am J Pathol
Title: Nuclear factor-kappaB enhances ErbB2-induced mammary tumorigenesis and neoangiogenesis in vivo.
Volume: 174
Issue: 5
Pages: 1910-20
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Publication
20628057 | J:166298
First Author: Ingalla EQ
Year: 2010
Journal: J Biol Chem
Title: Post-transcriptional mechanisms contribute to the suppression of the ErbB3 negative regulator protein Nrdp1 in mammary tumors.
Volume: 285
Issue: 37
Pages: 28691-7
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Publication
21159656 | J:167597
First Author: Liu M
Year: 2010
Journal: Cancer Res
Title: The canonical NF-kappaB pathway governs mammary tumorigenesis in transgenic mice and tumor stem cell expansion.
Volume: 70
Issue: 24
Pages: 10464-73
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