|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1701 to 1800 out of 2672 for Mapt

0.018s
Type Details Score
Publication  
First Author: Violet M
Year: 2015
Journal: Neurobiol Dis
Title: Prefibrillar Tau oligomers alter the nucleic acid protective function of Tau in hippocampal neurons in vivo.
Volume: 82
Pages: 540-551
Publication
First Author: Viney TJ
Year: 2022
Journal: Cell Rep
Title: Spread of pathological human Tau from neurons to oligodendrocytes and loss of high-firing pyramidal neurons in aging mice.
Volume: 41
Issue: 7
Pages: 111646
Publication
First Author: Louis JV
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Mice lacking phosphatase PP2A subunit PR61/B'delta (Ppp2r5d) develop spatially restricted tauopathy by deregulation of CDK5 and GSK3beta.
Volume: 108
Issue: 17
Pages: 6957-62
Strain
Attribute String: coisogenic, mutant strain, transgenic
Publication
First Author: Theunis C
Year: 2013
Journal: PLoS One
Title: Efficacy and safety of a liposome-based vaccine against protein Tau, assessed in tau.P301L mice that model tauopathy.
Volume: 8
Issue: 8
Pages: e72301
Publication
First Author: Menuet C
Year: 2011
Journal: PLoS One
Title: Age-related impairment of ultrasonic vocalization in Tau.P301L mice: possible implication for progressive language disorders.
Volume: 6
Issue: 10
Pages: e25770
Publication
First Author: Ahnaou A
Year: 2017
Journal: Sci Rep
Title: Emergence of early alterations in network oscillations and functional connectivity in a tau seeding mouse model of Alzheimer's disease pathology.
Volume: 7
Issue: 1
Pages: 14189
Publication
First Author: Lasagna-Reeves CA
Year: 2016
Journal: Neuron
Title: Reduction of Nuak1 Decreases Tau and Reverses Phenotypes in a Tauopathy Mouse Model.
Volume: 92
Issue: 2
Pages: 407-418
Publication
First Author: Leyns CEG
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: TREM2 deficiency attenuates neuroinflammation and protects against neurodegeneration in a mouse model of tauopathy.
Volume: 114
Issue: 43
Pages: 11524-11529
Publication  
First Author: Toral-Rios D
Year: 2024
Journal: J Exp Med
Title: Cholesterol 25-hydroxylase mediates neuroinflammation and neurodegeneration in a mouse model of tauopathy.
Volume: 221
Issue: 4
Publication
First Author: Mathys H
Year: 2024
Journal: Nature
Title: Single-cell multiregion dissection of Alzheimer's disease.
Volume: 632
Issue: 8026
Pages: 858-868
Strain
Attribute String: mutant strain, transgenic, congenic
Strain
Attribute String: congenic, mutant strain, targeted mutation
Strain
Attribute String: congenic, mutant strain, targeted mutation
Strain
Attribute String: congenic, mutant strain, targeted mutation
Strain
Attribute String: congenic, mutant strain, targeted mutation
Publication
First Author: Gahring LC
Year: 2018
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Lung eosinophilia induced by house dust mites or ovalbumin is modulated by nicotinic receptor α7 and inhibited by cigarette smoke.
Volume: 315
Issue: 4
Pages: L553-L562
Publication  
First Author: Rogers SW
Year: 2020
Journal: Front Immunol
Title: Age-Associated Tooth Loss and Oral Microbial Dysbiosis in a Mouse Genetic Model of Chronic Nicotine Exposure.
Volume: 11
Pages: 575200
Publication
First Author: Gahring LC
Year: 2017
Journal: PLoS One
Title: Nicotinic alpha 7 receptor expression and modulation of the lung epithelial response to lipopolysaccharide.
Volume: 12
Issue: 4
Pages: e0175367
Strain
Attribute String: congenic, mutant strain, targeted mutation, endonuclease-mediated mutation
Allele
Name: hypoxanthine phosphoribosyltransferase 1; targeted mutation 1, Diane P Hanger
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence, No functional change
Strain
Attribute String: mutant strain, other
Strain
Attribute String: congenic, mutant strain, other
Genotype
Symbol: Tg(Thy1-MAPT)22Schd/?
Background: B6.Cg-Tg(Thy1-MAPT)22Schd
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(GSK3B*S9A)1Vln/? Tg(Thy1-MAPT)1Vln/Tg(Thy1-MAPT)1Vln
Background: involves: FVB
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Tg(GSK3B*S9A)1Vln/? Tg(Thy1-MAPT)2Vln/Tg(Thy1-MAPT)2Vln
Background: involves: FVB
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Tg(Thy1-MAPT*P301L)2Vln/Tg(Thy1-MAPT*P301L)2Vln
Background: FVB/N-Tg(Thy1-MAPT*P301L)2Vln
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Tg(Thy1-MAPT)183Gotz/?
Background: B6.Cg-Tg(Thy1-MAPT)183Gotz
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(Thy1-MAPT*)30Schd/?
Background: involves: C57BL/6 * CBA
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Ppp2r5d/Ppp2r5d Tg(Thy1-MAPT)5Vln/?
Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Pitx2/Pitx2
Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6J
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Hprt1/Hprt1<+> Tg(PSEN1)5Dbo/?
Background: involves: 129P2/OlaHsd
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Tg(Thy1-MAPT)22Schd/?
Background: involves: C57BL/6 * CBA
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(Prnp-ITM2B*)1Ruvi/Tg(Prnp-ITM2B*)1Ruvi Tg(Prnp-MAPT*P301L)#Ruvi/Tg(Prnp-MAPT*P301L)#Ruvi
Background: involves: C3HeB/FeJ * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Tg(Thy1-MAPT*)30Schd/?
Background: involves: C57BL/6 * C57BL/6J * CBA * SJL
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(MAPT*V337M)1Gds/?
Background: B6J.Cg-Tg(MAPT*V337M)1Gds
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(Camk2a-tTA)1Mmay/? Tg(tetO-MAPT)32Lms/?
Background: B6.Cg-Tg(Camk2a-tTA)1Mmay Tg(tetO-MAPT)32Lms
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: App/App Mapt/Mapt
Background: involves: 129S/SvEv * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Syngr3/Syngr3<+> Tg(Prnp-MAPT*P301S)PS19Vle/?
Background: involves: C3H * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: App/App Mapt/Mapt
Background: B6.Cg-Mapt App
Zygosity: cx
Has Mutant Allele: true
Publication
First Author: Gammie SC
Year: 2024
Journal: PLoS One
Title: Large-scale gene expression changes in APP/PSEN1 and GFAP mutation models exhibit high congruence with Alzheimer's disease.
Volume: 19
Issue: 1
Pages: e0291995
Publication
First Author: Huang M
Year: 2020
Journal: Acta Neuropathol Commun
Title: Network analysis of the progranulin-deficient mouse brain proteome reveals pathogenic mechanisms shared in human frontotemporal dementia caused by GRN mutations.
Volume: 8
Issue: 1
Pages: 163
Publication
First Author: Gibbons GS
Year: 2017
Journal: J Neurosci
Title: GFP-Mutant Human Tau Transgenic Mice Develop Tauopathy Following CNS Injections of Alzheimer's Brain-Derived Pathological Tau or Synthetic Mutant Human Tau Fibrils.
Volume: 37
Issue: 47
Pages: 11485-11494
Publication
First Author: Sayed FA
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Differential effects of partial and complete loss of TREM2 on microglial injury response and tauopathy.
Volume: 115
Issue: 40
Pages: 10172-10177
Publication
First Author: Shi Y
Year: 2021
Journal: Neuron
Title: Overexpressing low-density lipoprotein receptor reduces tau-associated neurodegeneration in relation to apoE-linked mechanisms.
Volume: 109
Issue: 15
Pages: 2413-2426.e7
Publication
First Author: Shi Y
Year: 2019
Journal: J Exp Med
Title: Microglia drive APOE-dependent neurodegeneration in a tauopathy mouse model.
Volume: 216
Issue: 11
Pages: 2546-2561
Publication
First Author: Shin MK
Year: 2021
Journal: Cell
Title: Reducing acetylated tau is neuroprotective in brain injury.
Volume: 184
Issue: 10
Pages: 2715-2732.e23
Publication
First Author: Kulic L
Year: 2011
Journal: Neurobiol Aging
Title: Combined expression of tau and the Harlequin mouse mutation leads to increased mitochondrial dysfunction, tau pathology and neurodegeneration.
Volume: 32
Issue: 10
Pages: 1827-38
Publication  
First Author: Vanden Dries V
Year: 2017
Journal: Neurobiol Aging
Title: Amyloid precursor protein reduction enhances the formation of neurofibrillary tangles in a mutant tau transgenic mouse model.
Volume: 55
Pages: 202-212
Publication
First Author: Hurtado DE
Year: 2010
Journal: Am J Pathol
Title: A{beta} accelerates the spatiotemporal progression of tau pathology and augments tau amyloidosis in an Alzheimer mouse model.
Volume: 177
Issue: 4
Pages: 1977-88
Publication  
First Author: Cohen TJ
Year: 2011
Journal: Nat Commun
Title: The acetylation of tau inhibits its function and promotes pathological tau aggregation.
Volume: 2
Pages: 252
Publication  
First Author: Woo JA
Year: 2022
Journal: Life Sci Alliance
Title: β-arrestin1 promotes tauopathy by transducing GPCR signaling, disrupting microtubules and autophagy.
Volume: 5
Issue: 3
Publication
First Author: Messing L
Year: 2013
Journal: Neurobiol Aging
Title: Cascade of tau toxicity in inducible hippocampal brain slices and prevention by aggregation inhibitors.
Volume: 34
Issue: 5
Pages: 1343-1354
Publication  
First Author: Sebastián-Serrano Á
Year: 2022
Journal: Neurobiol Dis
Title: TNAP upregulation is a critical factor in Tauopathies and its blockade ameliorates neurotoxicity and increases life-expectancy.
Volume: 165
Pages: 105632
Publication
First Author: Ishihara T
Year: 1999
Journal: Neuron
Title: Age-dependent emergence and progression of a tauopathy in transgenic mice overexpressing the shortest human tau isoform.
Volume: 24
Issue: 3
Pages: 751-62
Publication
First Author: Nakashima H
Year: 2004
Journal: Free Radic Biol Med
Title: Effects of alpha-tocopherol on an animal model of tauopathies.
Volume: 37
Issue: 2
Pages: 176-86
Strain
Attribute String: congenic, mutant strain, targeted mutation, transgenic
Strain
Attribute String: congenic, mutant strain, targeted mutation, transgenic
Strain
Attribute String: congenic, mutant strain, targeted mutation, transgenic
Publication
First Author: Schweig JE
Year: 2017
Journal: Acta Neuropathol Commun
Title: Alzheimer's disease pathological lesions activate the spleen tyrosine kinase.
Volume: 5
Issue: 1
Pages: 69
Strain
Attribute String: Not specified
Publication
First Author: Ferreira S
Year: 2021
Journal: Eur J Neurosci
Title: Oligodendrogenesis increases in hippocampal grey and white matter prior to locomotor or memory impairment in an adult mouse model of tauopathy.
Volume: 54
Issue: 5
Pages: 5762-5784
Publication
First Author: Enioutina EY
Year: 2015
Journal: PLoS One
Title: The nicotinic receptor Alpha7 impacts the mouse lung response to LPS through multiple mechanisms.
Volume: 10
Issue: 3
Pages: e0121128
Publication
First Author: Yao PJ
Year: 2005
Journal: Biochem Biophys Res Commun
Title: Preserved synaptic vesicle recycling in hippocampal neurons in a mouse Alzheimer's disease model.
Volume: 330
Issue: 1
Pages: 34-8
Publication
First Author: Caillava C
Year: 2014
Journal: Neurobiol Aging
Title: Study on Aβ34 biology and detection in transgenic mice brains.
Volume: 35
Issue: 7
Pages: 1570-81
Publication
First Author: Parrella E
Year: 2013
Journal: Aging Cell
Title: Protein restriction cycles reduce IGF-1 and phosphorylated Tau, and improve behavioral performance in an Alzheimer's disease mouse model.
Volume: 12
Issue: 2
Pages: 257-68
Publication
First Author: Berger Z
Year: 2007
Journal: J Neurosci
Title: Accumulation of pathological tau species and memory loss in a conditional model of tauopathy.
Volume: 27
Issue: 14
Pages: 3650-62
Publication
First Author: Ghosh D
Year: 2014
Journal: Neurobiol Aging
Title: Dual-energy precursor and nuclear erythroid-related factor 2 activator treatment additively improve redox glutathione levels and neuron survival in aging and Alzheimer mouse neurons upstream of reactive oxygen species.
Volume: 35
Issue: 1
Pages: 179-90
Publication
First Author: Zhao L
Year: 2011
Journal: Neurobiol Aging
Title: 17β-Estradiol regulates insulin-degrading enzyme expression via an ERβ/PI3-K pathway in hippocampus: relevance to Alzheimer's prevention.
Volume: 32
Issue: 11
Pages: 1949-63
Publication
First Author: Martin SA
Year: 2014
Journal: PLoS One
Title: Maternal high-fat diet worsens memory deficits in the triple-transgenic (3xTgAD) mouse model of Alzheimer's disease.
Volume: 9
Issue: 6
Pages: e99226
Publication
First Author: Zumkehr J
Year: 2015
Journal: Neurobiol Aging
Title: Ceftriaxone ameliorates tau pathology and cognitive decline via restoration of glial glutamate transporter in a mouse model of Alzheimer's disease.
Volume: 36
Issue: 7
Pages: 2260-2271
Publication
First Author: Desai MK
Year: 2009
Journal: Glia
Title: Triple-transgenic Alzheimer's disease mice exhibit region-specific abnormalities in brain myelination patterns prior to appearance of amyloid and tau pathology.
Volume: 57
Issue: 1
Pages: 54-65
Publication  
First Author: Isopi E
Year: 2015
Journal: Neurobiol Dis
Title: Pyruvate prevents the development of age-dependent cognitive deficits in a mouse model of Alzheimer's disease without reducing amyloid and tau pathology.
Volume: 81
Pages: 214-24
Publication
First Author: Montgomery SL
Year: 2013
Journal: Am J Pathol
Title: Chronic neuron- and age-selective down-regulation of TNF receptor expression in triple-transgenic Alzheimer disease mice leads to significant modulation of amyloid- and Tau-related pathologies.
Volume: 182
Issue: 6
Pages: 2285-97
Publication
First Author: Walls KC
Year: 2012
Journal: J Biol Chem
Title: Swedish Alzheimer mutation induces mitochondrial dysfunction mediated by HSP60 mislocalization of amyloid precursor protein (APP) and beta-amyloid.
Volume: 287
Issue: 36
Pages: 30317-27
Publication
First Author: Caruso D
Year: 2013
Journal: Neurobiol Aging
Title: Age-related changes in neuroactive steroid levels in 3xTg-AD mice.
Volume: 34
Issue: 4
Pages: 1080-9
Publication  
First Author: Baeta-Corral R
Year: 2015
Journal: Neurosci Lett
Title: Tail-flick test response in 3×Tg-AD mice at early and advanced stages of disease.
Volume: 600
Pages: 158-63
Publication
First Author: Giuliani D
Year: 2014
Journal: Neurobiol Aging
Title: Melanocortins protect against progression of Alzheimer's disease in triple-transgenic mice by targeting multiple pathophysiological pathways.
Volume: 35
Issue: 3
Pages: 537-47
Publication
First Author: Rohn TT
Year: 2008
Journal: J Neurosci
Title: Lack of pathology in a triple transgenic mouse model of Alzheimer's disease after overexpression of the anti-apoptotic protein Bcl-2.
Volume: 28
Issue: 12
Pages: 3051-9
Publication
First Author: Kashiwaya Y
Year: 2013
Journal: Neurobiol Aging
Title: A ketone ester diet exhibits anxiolytic and cognition-sparing properties, and lessens amyloid and tau pathologies in a mouse model of Alzheimer's disease.
Volume: 34
Issue: 6
Pages: 1530-9
Publication
First Author: Liu D
Year: 2013
Journal: Neurobiol Aging
Title: Nicotinamide forestalls pathology and cognitive decline in Alzheimer mice: evidence for improved neuronal bioenergetics and autophagy procession.
Volume: 34
Issue: 6
Pages: 1564-80
Publication  
First Author: Mota SI
Year: 2014
Journal: Exp Neurol
Title: Impaired Src signaling and post-synaptic actin polymerization in Alzheimer's disease mice hippocampus--linking NMDA receptors and the reelin pathway.
Volume: 261
Pages: 698-709
Publication
First Author: Mastrangelo MA
Year: 2009
Journal: Am J Pathol
Title: Interferon-{gamma} differentially affects Alzheimer's disease pathologies and induces neurogenesis in triple transgenic-AD mice.
Volume: 175
Issue: 5
Pages: 2076-88
Strain
Attribute String: transgenic, mutant strain, congenic
Publication
First Author: Lee SH
Year: 2021
Journal: Neuron
Title: Trem2 restrains the enhancement of tau accumulation and neurodegeneration by β-amyloid pathology.
Volume: 109
Issue: 8
Pages: 1283-1301.e6
Publication
First Author: van Eersel J
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Sodium selenate mitigates tau pathology, neurodegeneration, and functional deficits in Alzheimer's disease models.
Volume: 107
Issue: 31
Pages: 13888-93
Publication
First Author: Lee SH
Year: 2021
Journal: Cell Rep
Title: TREM2-independent oligodendrocyte, astrocyte, and T cell responses to tau and amyloid pathology in mouse models of Alzheimer disease.
Volume: 37
Issue: 13
Pages: 110158
Publication
First Author: Grueninger F
Year: 2010
Journal: Neurobiol Dis
Title: Phosphorylation of Tau at S422 is enhanced by Abeta in TauPS2APP triple transgenic mice.
Volume: 37
Issue: 2
Pages: 294-306
Publication
First Author: Rodríguez-Navarro JA
Year: 2010
Journal: Neurobiol Dis
Title: Trehalose ameliorates dopaminergic and tau pathology in parkin deleted/tau overexpressing mice through autophagy activation.
Volume: 39
Issue: 3
Pages: 423-38
Publication
First Author: Menéndez J
Year: 2006
Journal: Hum Mol Genet
Title: Suppression of Parkin enhances nigrostriatal and motor neuron lesion in mice over-expressing human-mutated tau protein.
Volume: 15
Issue: 13
Pages: 2045-58
Publication
First Author: Ponnusamy M
Year: 2023
Journal: Brain
Title: Loss of forebrain BIN1 attenuates hippocampal pathology and neuroinflammation in a tauopathy model.
Volume: 146
Issue: 4
Pages: 1561-1579
Publication
First Author: Tu J
Year: 2022
Journal: J Biol Chem
Title: Aging-associated REGγ proteasome decline predisposes to tauopathy.
Volume: 298
Issue: 11
Pages: 102571
Publication  
First Author: Dávila-Bouziguet E
Year: 2019
Journal: Neurobiol Dis
Title: Differential accumulation of Tau phosphorylated at residues Thr231, Ser262 and Thr205 in hippocampal interneurons and its modulation by Tau mutations (VLW) and amyloid-β peptide.
Volume: 125
Pages: 232-244
Publication
First Author: Jiang Y
Year: 2023
Journal: Sci Adv
Title: Single-domain antibody-based noninvasive in vivo imaging of α-synuclein or tau pathology.
Volume: 9
Issue: 19
Pages: eadf3775
Publication  
First Author: Woo JA
Year: 2019
Journal: Commun Biol
Title: Activated cofilin exacerbates tau pathology by impairing tau-mediated microtubule dynamics.
Volume: 2
Pages: 112
Publication
First Author: Bright J
Year: 2015
Journal: Neurobiol Aging
Title: Human secreted tau increases amyloid-beta production.
Volume: 36
Issue: 2
Pages: 693-709
Publication  
First Author: Song HL
Year: 2023
Journal: J Clin Invest
Title: Monoclonal antibody Y01 prevents tauopathy progression induced by lysine 280-acetylated tau in cell and mouse models.
Volume: 133
Issue: 8
Publication
First Author: Ising C
Year: 2019
Journal: Nature
Title: NLRP3 inflammasome activation drives tau pathology.
Volume: 575
Issue: 7784
Pages: 669-673
Strain
Attribute String: congenic, mutant strain, targeted mutation, transgenic
Publication
First Author: Saul A
Year: 2013
Journal: Neurobiol Aging
Title: Accelerated tau pathology with synaptic and neuronal loss in a novel triple transgenic mouse model of Alzheimer's disease.
Volume: 34
Issue: 11
Pages: 2564-73