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Search results 1701 to 1800 out of 2039 for Met

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Type Details Score
Publication
10355613 | J:55291
First Author: Rüsch A
Year: 1999
Journal: Hear Res
Title: Mechano-electrical transduction in mice lacking the alpha-subunit of the epithelial sodium channel.
Volume: 131
Issue: 1-2
Pages: 170-6
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Publication
10430667 | J:57004
First Author: Priat C
Year: 1999
Journal: Mamm Genome
Title: Characterization of 463 type I markers suitable for dog genome mapping.
Volume: 10
Issue: 8
Pages: 803-13
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Publication
11896610 | J:75480
First Author: De Maria R
Year: 2002
Journal: Oncogene
Title: Feline STK gene expression in mammary carcinomas.
Volume: 21
Issue: 11
Pages: 1785-90
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Publication
11989784 | J:75960
First Author: El-Nahas A
Year: 2002
Journal: Biochem Genet
Title: Differential effects of the KitW mutation with other Kit allelic combinations on male sterility among inter- or intrasubspecific hybrids in mice.
Volume: 40
Issue: 1-2
Pages: 13-25
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Publication
10229079 | J:78025
First Author: Granziero L
Year: 1999
Journal: Eur J Immunol
Title: Adoptive immunotherapy prevents prostate cancer in a transgenic animal model.
Volume: 29
Issue: 4
Pages: 1127-38
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Publication
12147692 | J:79289
First Author: Wang D
Year: 2002
Journal: J Biol Chem
Title: Activation of Ras/Erk pathway by a novel MET-interacting protein RanBPM.
Volume: 277
Issue: 39
Pages: 36216-22
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Publication
12419829 | J:80007
First Author: Chen YQ
Year: 2002
Journal: Carcinogenesis
Title: Multiple pulmonary adenomas in the lung of transgenic mice overexpressing the RON receptor tyrosine kinase. Recepteur d'origine nantais.
Volume: 23
Issue: 11
Pages: 1811-9
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Publication
12529314 | J:81710
First Author: Park YG
Year: 2003
Journal: Genome Res
Title: Multiple cross and inbred strain haplotype mapping of complex-trait candidate genes.
Volume: 13
Issue: 1
Pages: 118-21
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Publication
12763579 | J:83759
First Author: Ramos M
Year: 2003
Journal: Brain Res Dev Brain Res
Title: Developmental changes in the Ca2+-regulated mitochondrial aspartate-glutamate carrier aralar1 in brain and prominent expression in the spinal cord.
Volume: 143
Issue: 1
Pages: 33-46
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Publication
12828987 | J:84737
First Author: Hamachi T
Year: 2003
Journal: Arch Oral Biol
Title: Association between palatal morphogenesis and Pax9 expression pattern in CL/Fr embryos with clefting during palatal development.
Volume: 48
Issue: 8
Pages: 581-7
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Publication
15479430 | J:93362
First Author: Stewart TJ
Year: 2004
Journal: Immunol Cell Biol
Title: Tumour susceptibility to innate and adaptive immunotherapy changes during tumour maturation.
Volume: 82
Issue: 5
Pages: 455-61
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Publication
16288040 | J:103402
First Author: Chu F
Year: 2005
Journal: Cancer Res
Title: Identification of an inactivating cysteine switch in protein kinase Cepsilon, a rational target for the design of protein kinase Cepsilon-inhibitory cancer therapeutics.
Volume: 65
Issue: 22
Pages: 10478-85
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Publication
16627470 | J:114359
First Author: Hales TG
Year: 2006
Journal: J Biol Chem
Title: An asymmetric contribution to gamma-aminobutyric type A receptor function of a conserved lysine within TM2-3 of alpha1, beta2, and gamma2 subunits.
Volume: 281
Issue: 25
Pages: 17034-43
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Publication
16790084 | J:114940
First Author: Moshitch-Moshkovitz S
Year: 2006
Journal: Neoplasia
Title: In vivo direct molecular imaging of early tumorigenesis and malignant progression induced by transgenic expression of GFP-Met.
Volume: 8
Issue: 5
Pages: 353-63
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Publication
16869757 | J:116749
 
First Author: Tward AD
Year: 2005
Journal: Cold Spring Harb Symp Quant Biol
Title: Genomic progression in mouse models for liver tumors.
Volume: 70
Pages: 217-24
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Publication
17713024 | J:128615
 
First Author: Shafer-Weaver K
Year: 2007
Journal: Adv Exp Med Biol
Title: T cell tolerance to tumors and cancer immunotherapy.
Volume: 601
Pages: 357-68
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Publication
18620091 | J:139713
 
First Author: Wagh PK
Year: 2008
Journal: Adv Cancer Res
Title: Met-related receptor tyrosine kinase Ron in tumor growth and metastasis.
Volume: 100
Pages: 1-33
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Publication
17082576 | J:140499
First Author: Murugaiyan G
Year: 2006
Journal: J Immunol
Title: Functional dichotomy in CD40 reciprocally regulates effector T cell functions.
Volume: 177
Issue: 10
Pages: 6642-9
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Publication
19158091 | J:148740
First Author: Maarouf AB
Year: 2009
Journal: J Biol Chem
Title: Novel determinants of epithelial sodium channel gating within extracellular thumb domains.
Volume: 284
Issue: 12
Pages: 7756-65
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Publication
19393645 | J:151267
First Author: Li J
Year: 2009
Journal: Exp Cell Res
Title: Hepatocyte growth factor (HGF) signals through SHP2 to regulate primary mouse myoblast proliferation.
Volume: 315
Issue: 13
Pages: 2284-92
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Publication
19565641 | J:157055
First Author: Shuda K
Year: 2009
Journal: Mol Reprod Dev
Title: Aurora kinase B modulates chromosome alignment in mouse oocytes.
Volume: 76
Issue: 11
Pages: 1094-105
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Publication
21186337 | J:173588
First Author: Kanazawa T
Year: 2011
Journal: J Vet Med Sci
Title: Hepatocyte nuclear factor 4 alpha is associated with mesenchymal-epithelial transition in developing kidneys of C57BL/6 mice.
Volume: 73
Issue: 5
Pages: 601-7
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Publication
21402728 | J:173829
First Author: Kwast LM
Year: 2011
Journal: Toxicol Sci
Title: Oral exposure to drugs with immune-adjuvant potential induces hypersensitivity responses to the reporter antigen TNP-OVA.
Volume: 121
Issue: 2
Pages: 312-9
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Publication
21554929 | J:177755
First Author: Zhang L
Year: 2011
Journal: Biochim Biophys Acta
Title: Ganglioside GD1a negatively regulates hepatocyte growth factor expression through caveolin-1 at the transcriptional level in murine osteosarcoma cells.
Volume: 1810
Issue: 8
Pages: 759-68
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Publication
22552292 | J:189319
First Author: Xu L
Year: 2012
Journal: Cancer Res
Title: Combined EGFR/MET or EGFR/HSP90 inhibition is effective in the treatment of lung cancers codriven by mutant EGFR containing T790M and MET.
Volume: 72
Issue: 13
Pages: 3302-11
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Publication
23002209 | J:190961
First Author: Gao D
Year: 2012
Journal: Cancer Res
Title: Microenvironmental regulation of epithelial-mesenchymal transitions in cancer.
Volume: 72
Issue: 19
Pages: 4883-9
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Publication
23474494 | J:202800
First Author: Morrison CD
Year: 2013
Journal: Cancer Lett
Title: The relevance of the TGF-β Paradox to EMT-MET programs.
Volume: 341
Issue: 1
Pages: 30-40
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Publication
24375723 | J:207505
First Author: Rosafio K
Year: 2014
Journal: Glia
Title: Oxygen tension controls the expression of the monocarboxylate transporter MCT4 in cultured mouse cortical astrocytes via a hypoxia-inducible factor-1α-mediated transcriptional regulation.
Volume: 62
Issue: 3
Pages: 477-90
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Publication
24421884 | J:211938
First Author: Chen H
Year: 2014
Journal: PLoS One
Title: A provisional gene regulatory atlas for mouse heart development.
Volume: 9
Issue: 1
Pages: e83364
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Publication
25991709 | J:227147
First Author: Cook MN
Year: 2015
Journal: Physiol Genomics
Title: Identification of candidate genes that underlie the QTL on chromosome 1 that mediates genetic differences in stress-ethanol interactions.
Volume: 47
Issue: 8
Pages: 308-17
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Publication
25362253 | J:227804
First Author: Hasnain SZ
Year: 2014
Journal: Nat Med
Title: Glycemic control in diabetes is restored by therapeutic manipulation of cytokines that regulate beta cell stress.
Volume: 20
Issue: 12
Pages: 1417-26
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Publication
25946048 | J:235350
First Author: Li R
Year: 2015
Journal: PLoS One
Title: Abl Kinases Regulate HGF/Met Signaling Required for Epithelial Cell Scattering, Tubulogenesis and Motility.
Volume: 10
Issue: 5
Pages: e0124960
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Publication
28916718 | J:249556
First Author: Ntostis P
Year: 2017
Journal: Reproduction
Title: Potential sperm contributions to the murine zygote predicted by in silico analysis.
Volume: 154
Issue: 6
Pages: 777-788
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Publication
28807594 | J:252123
First Author: Puliga E
Year: 2017
Journal: Am J Pathol
Title: Thyroid Hormone Receptor-β Agonist GC-1 Inhibits Met-β-Catenin-Driven Hepatocellular Cancer.
Volume: 187
Issue: 11
Pages: 2473-2485
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Publication
28372532 | J:267330
First Author: Lin J
Year: 2017
Journal: Otolaryngol Head Neck Surg
Title: Panel 3: Genetics and Precision Medicine of Otitis Media.
Volume: 156
Issue: 4_suppl
Pages: S41-S50
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Publication
30097516 | J:271041
First Author: Lin L
Year: 2018
Journal: J Biol Chem
Title: The homeobox transcription factor MSX2 partially mediates the effects of bone morphogenetic protein 4 (BMP4) on somatic cell reprogramming.
Volume: 293
Issue: 38
Pages: 14905-14915
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Publication
31120888 | J:275740
First Author: Fergusson DA
Year: 2019
Journal: PLoS One
Title: Reporting preclinical anesthesia study (REPEAT): Evaluating the quality of reporting in the preclinical anesthesiology literature.
Volume: 14
Issue: 5
Pages: e0215221
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Publication
32238360 | J:290437
First Author: Clarke M
Year: 2020
Journal: Cancer Discov
Title: Infant High-Grade Gliomas Comprise Multiple Subgroups Characterized by Novel Targetable Gene Fusions and Favorable Outcomes.
Volume: 10
Issue: 7
Pages: 942-963
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Publication
32800944 | J:301401
First Author: Wen D
Year: 2020
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Bromodomain and Extraterminal (BET) protein inhibition suppresses tumor progression and inhibits HGF-MET signaling through targeting cancer-associated fibroblasts in colorectal cancer.
Volume: 1866
Issue: 12
Pages: 165923
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Publication
29650351 | J:301849
 
First Author: Ou K
Year: 2018
Journal: Mol Metab
Title: Overexpression of ST5, an activator of Ras, has no effect on β-cell proliferation in adult mice.
Volume: 11
Pages: 212-217
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Publication
33077644 | J:300710
First Author: Ablack JN
Year: 2020
Journal: J Immunol
Title: MARCH Proteins Mediate Responses to Antitumor Antibodies.
Volume: 205
Issue: 10
Pages: 2883-2892
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Publication
32899784 | J:304158
 
First Author: Yamaguchi S
Year: 2020
Journal: Int J Mol Sci
Title: A Mechanosensitive Channel, Mouse Transmembrane Channel-Like Protein 1 (Mtmc1) Is Translated from a Splice Variant mTmc1ex1 but Not from the Other Variant mTmc1ex2.
Volume: 21
Issue: 18
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Publication
32587258 | J:305422
First Author: Wang Y
Year: 2020
Journal: Cell Death Dis
Title: TFAP2C facilitates somatic cell reprogramming by inhibiting c-Myc-dependent apoptosis and promoting mesenchymal-to-epithelial transition.
Volume: 11
Issue: 6
Pages: 482
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Publication
33526511 | J:305548
First Author: Huang L
Year: 2021
Journal: Cancer Res
Title: Targeting Pan-ETS Factors Inhibits Melanoma Progression.
Volume: 81
Issue: 8
Pages: 2071-2085
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Publication
25071152 | J:315544
First Author: Hudson J
Year: 2014
Journal: Mol Cell Biol
Title: p66ShcA promotes breast cancer plasticity by inducing an epithelial-to-mesenchymal transition.
Volume: 34
Issue: 19
Pages: 3689-701
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Publication
34965503 | J:319772
 
First Author: Sandrini L
Year: 2022
Journal: Biomed Pharmacother
Title: The α2-adrenergic receptor pathway modulating depression influences the risk of arterial thrombosis associated with BDNFVal66Met polymorphism.
Volume: 146
Pages: 112557
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Publication
34346063 | J:341297
First Author: Yan K
Year: 2022
Journal: J Cell Physiol
Title: BAIAP2L2 is required for the maintenance of mechanotransducing stereocilia of cochlear hair cells.
Volume: 237
Issue: 1
Pages: 774-788
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Publication
38696518 | J:349066
First Author: Nagarajan A
Year: 2024
Journal: PLoS Genet
Title: Collaborative Cross mice have diverse phenotypic responses to infection with Methicillin-resistant Staphylococcus aureus USA300.
Volume: 20
Issue: 5
Pages: e1011229
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Publication
22172720 | J:178598
First Author: Damsky WE
Year: 2011
Journal: Cancer Cell
Title: β-catenin signaling controls metastasis in Braf-activated Pten-deficient melanomas.
Volume: 20
Issue: 6
Pages: 741-54
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Publication
31050682 | J:353640
First Author: Yamada M
Year: 2019
Journal: PLoS Genet
Title: Functional robustness of adult spermatogonial stem cells after induction of hyperactive Hras.
Volume: 15
Issue: 5
Pages: e1008139
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Publication
1943695 | -
First Author: Weissbach H
Year: 1991
Journal: Mol Microbiol
Title: Regulation of methionine synthesis in Escherichia coli.
Volume: 5
Issue: 7
Pages: 1593-7
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Publication
15858169 | -
First Author: Xie Y
Year: 2005
Journal: J Biochem
Title: Structural reorganization of the copper binding site involving Thr15 of mavicyanin from Cucurbita pepo medullosa (zucchini) upon reduction.
Volume: 137
Issue: 4
Pages: 455-61
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Publication
9761472 | -
First Author: Nersissian AM
Year: 1998
Journal: Protein Sci
Title: Uclacyanins, stellacyanins, and plantacyanins are distinct subfamilies of phytocyanins: plant-specific mononuclear blue copper proteins.
Volume: 7
Issue: 9
Pages: 1915-29
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Publication
10770939 | -
First Author: Feltzer RE
Year: 2000
Journal: J Biol Chem
Title: Alkaline proteinase inhibitor of Pseudomonas aeruginosa. Interaction of native and N-terminally truncated inhibitor proteins with Pseudomonas metalloproteinases.
Volume: 275
Issue: 28
Pages: 21002-9
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Protein
Q8CA64
Organism: Mus musculus/domesticus
Length: 207  
Fragment?: true
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Protein
A0A1Y7VNJ8
Organism: Mus musculus/domesticus
Length: 78  
Fragment?: true
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Protein
A0A1Y7VNY4
Organism: Mus musculus/domesticus
Length: 95  
Fragment?: true
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Protein
A0A1Y7VMT6
Organism: Mus musculus/domesticus
Length: 220  
Fragment?: true
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Publication
5089608 | -
First Author: Stigbrand T
Year: 1971
Journal: Biochim Biophys Acta
Title: Structural properties of umecyanin. A copper protein from horseradish root.
Volume: 236
Issue: 1
Pages: 246-52
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Publication
11945593 | -
First Author: Stigbrand T
Year: 1971
Journal: FEBS Lett
Title: On the state of copper in the blue protein umecyanin.
Volume: 12
Issue: 5
Pages: 260-262
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Protein Domain
IPR003245 | Phytocyanin_dom
Type: Domain
Description: Among the blue copper proteins with a single type I (or "blue") mononuclearcopper site, the plant-specific phytocyanins constitute a distinct subfamilythat can be further subdivided into the families of uclacyanins, stellacyanins,plantacyanins, and early nodulins. Stellacyanins have a blue coppercoordinated by two His, one Cys and one Gln. In plantacyanins and uclacyanins,the ligands of the type-I Cu sites are two His, one Cys and one Met [, , , ]. Early nodulins lack amino acid residues that coordinate Cu, so they are believed to be involved in unknown processes without binding Cu []. Phytocyanins are found in chloropasts of higher plants.The phytocyanin domain has a core of seven polypeptide strands arranged as aβ-sandwich comprising two β-sheets, β-sheet I and β-sheet II. β-sheet I consists of three β-strands and β-sheet IIconsists of four β-strands. A disulfide bridge close the metal centre ischaracteristic for phytocyanins, in contrast to azurins, pseudoazurins, andplastocyanins, where a disulfide bond is located on the distal side of theβ-barrel. This disuldide bridge may play a crucial role in maintaining thetertiary structure of the protein and/or the formation of the copper bindingcentre because one of the His ligands of copper is followed directly by abridging Cys residue [, , , ]. Some members of this family (P93328) may not bind copper due to the lack of key residues. Some proteins known to contain a phytocyanin domain are listed below:Cucumber basic protein (CBP).Spinach basic protein (SBP).Cucumber stellacyanin (CST).Zucchini mavicyanin.Horseradish umecyanin [, ]. Some of the proteins in this family are allergens. The allergens in this family include allergens with the following designations: Amb a 3.
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Protein Domain
IPR022815 | Inh
Type: Family
Description: This family of proteins represent monomeric serralysin inhibitors of about 125 residues, which interact with specific metalloprotease which are synthesised by serralysin secretors and characterised by being plant, insect and animal pathogens. It is probable that the serralysin inhibitors protect the host from proteolysis during export of the protease. The members of this family belong to MEROPS proteinase inhibitor family I38, clan IK.X-ray crystallography of a complex between the Serratia marcescens protease, SmaPI, and the inhibitor of Erwinia chrysanthemi, Inh, reveals that Inh is folded into an eight-stranded b-barrel with an N-terminal trunk of 10 residues. Residues 1-5 occupy part of the extended active site of the proteinase, thereby preventing access of the substrate. Residues 6-10 form a linker that connects the N-terminal proteinase-binding peptide to the body of the b-barrel. The backbone carbonyl of Ser-1 interacts with the catalytic zinc; the Ser-2 side chain occupies the S1'-binding site and also forms a hydrogen bond to the carboxyl end of the catalytic Glu, whereas Leu-3 occupies the S2' recognition site. Penetration of the trunk region further than 5 residues into the substrate binding cleft appears to be prevented by the b-barrel, which itself interacts with the proteinase near its Met turn (19). Peptide mimetics of the trunk at concentrations up to about 100 mM do not inhibit the protease, demonstrating that the barrel is essential for inhibitory activity [, ].Structurally and functionally these inhibitors are closely related to the lipocalins, fatty acid-binding proteins, avidins and the enigmatic triabin.Together these five protein families constitute the calycin superfamily []. The proteins are characterised by their high specificity for small hydrophobic molecules and by their ability to form complexes with soluble macromolecules either through intramolecular disulphides or protein-protein interactions [].
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Protein Domain
IPR001341 | Asp_kinase
Type: Domain
Description: Bacteria, plants and fungi metabolise aspartic acid to produce four amino acids - lysine, threonine, methionine and isoleucine - in a series of reactions known as the aspartate pathway. Additionally, several important metabolic intermediates are produced by these reactions, such as diaminopimelic acid, an essential component of bacterial cell wall biosynthesis, and dipicolinic acid, which is involved in sporulation in Gram-positive bacteria. Members of the animal kingdom do not posses this pathway and must therefore acquire these essential amino acids through their diet. Research into improving the metabolic flux through this pathway has the potential to increase the yield of the essential amino acids in important crops, thus improving their nutritional value. Additionally, since the enzymes are not present in animals, inhibitors of them are promising targets for the development of novel antibiotics and herbicides. For more information see [].Aspartate kinase () (AK) catalyzes the first reaction in the aspartate pathway; the phosphorylation of aspartate. The product of this reaction can then be used in the biosynthesis of lysine or in the pathway leading to homoserine, which participates in the biosynthesis of threonine, isoleucine and methionine [].In bacteria there are three different aspartate kinase isozymes which differ in sensitivity to repression and inhibition by Lys, Met and Thr. AK1 and AK2 are bifunctional enzymes which both consist of an N-terminal AK domain and a C-terminal homoserine dehydrogenase domain. AK1 is involved in threonine biosynthesis and AK2, in that of methionine. The third isozyme, AK3 is monofunctional and involved in lysine synthesis. In archaea and plants there may be a single isozyme of AK which in plants is multifunctional.
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Protein Domain
IPR021140 | Inh/Omp19
Type: Domain
Description: This entry represents the metalloprotease inhibitor I38, as well as the outer membrane lipoprotein Omp19.This family of proteins represent monomeric serralysin inhibitors of about 125 residues, which interact with specific metalloprotease which are synthesised by serralysin secretors and characterised by being plant, insect and animal pathogens. It is probable that the serralysin inhibitors protect the host from proteolysis during export of the protease. The members of this family belong to MEROPS proteinase inhibitor family I38, clan IK.X-ray crystallography of a complex between the Serratia marcescens protease, SmaPI, and the inhibitor of Erwinia chrysanthemi, Inh, reveals that Inh is folded into an eight-stranded b-barrel with an N-terminal trunk of 10 residues. Residues 1-5 occupy part of the extended active site of the proteinase, thereby preventing access of the substrate. Residues 6-10 form a linker that connects the N-terminal proteinase-binding peptide to the body of the b-barrel. The backbone carbonyl of Ser-1 interacts with the catalytic zinc; the Ser-2 side chain occupies the S1'-binding site and also forms a hydrogen bond to the carboxyl end of the catalytic Glu, whereas Leu-3 occupies the S2' recognition site. Penetration of the trunk region further than 5 residues into the substrate binding cleft appears to be prevented by the b-barrel, which itself interacts with the proteinase near its Met turn (19). Peptide mimetics of the trunk at concentrations up to about 100 mM do not inhibit the protease, demonstrating that the barrel is essential for inhibitory activity [, ].Structurally and functionally these inhibitors are closely related to the lipocalins, fatty acid-binding proteins, avidins and the enigmatic triabin.Together these five protein families constitute the calycin superfamily []. The proteins are characterised by their high specificity for small hydrophobic molecules and by their ability to form complexes with soluble macromolecules either through intramolecular disulphides or protein-protein interactions [].
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Protein Coding Gene
MGI:97583 | Pik3r1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:98354 | Sos1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:98397 | Src
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1206581 | Pik3ca
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
P26450
Organism: Mus musculus/domesticus
Length: 724  
Fragment?: false
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Protein
P05480
Organism: Mus musculus/domesticus
Length: 535  
Fragment?: false
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Protein
Q62245
Organism: Mus musculus/domesticus
Length: 1319  
Fragment?: false
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Protein
P42337
Organism: Mus musculus/domesticus
Length: 1068  
Fragment?: false
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Publication
2703500 | J:37044
First Author: Lindberg R
Year: 1989
Journal: J Biol Chem
Title: The structure and characterization of type I P-450(15) alpha gene as major steroid 15 alpha-hydroxylase and its comparison with type II P-450(15) alpha gene.
Volume: 264
Issue: 11
Pages: 6465-71
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Publication
6165997 | J:6520
First Author: Gates FT 3rd
Year: 1981
Journal: Proc Natl Acad Sci U S A
Title: Complete amino acid sequence of murine beta 2-microglobulin: structural evidence for strain-related polymorphism.
Volume: 78
Issue: 1
Pages: 554-8
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Publication
10455109 | J:57060
First Author: Loewen SK
Year: 1999
Journal: J Biol Chem
Title: Identification of amino acid residues responsible for the pyrimidine and purine nucleoside specificities of human concentrative Na(+) nucleoside cotransporters hCNT1 and hCNT2.
Volume: 274
Issue: 35
Pages: 24475-84
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Publication
37314160 | J:339317
 
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