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Search results 1701 to 1795 out of 1795 for Nkx2-5

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Type Details Score
Genotype
Genotype
Symbol: Tmsb4x/? Tg(Nkx2-5-cre)9Eno/?
Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: t/? +/? t<+>/? Del(17D17Jcs40-D17Mit198)7Jcs/?
Background: involves: 129S4/SvJae * C3HeB/FeJ * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Irx3/Irx3 Irx5/Irx5 Tg(Nkx2-5-cre)9Eno/?
Background: Not Specified
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nkx2-5/Nkx2-5
Background: B6.129-Nkx2-5
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nkx2-5/Nkx2-5
Background: involves: 129S4/SvJae * C57BL/6 * SJL * Swiss Webster
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Syne1/Syne1 Syne2/Syne2 Tg(Nkx2-5-cre)9Eno/?
Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * Black Swiss
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Syne1/Syne1 Tg(Nkx2-5-cre)9Eno/?
Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * Black Swiss
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Commd9/Commd9 Tg(Nkx2-5-cre)9Eno/?
Background: involves: C57BL/6N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nkx2-5/Nkx2-5<+>
Background: B6J.Cg-Nkx2-5/Mwc
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nkx2-5/Nkx2-5<+>
Background: B6J.Cg-Nkx2-5/Mwc
Zygosity: ht
Has Mutant Allele: true
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DO Term
DOID:0110112 | atrial heart septal defect 7
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Genotype
Genotype
Symbol: Zswim8/Zswim8 Tg(Nkx2-5-cre)9Eno/?
Background: involves: C57BL/6J
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rac1/Rac1 Tg(Nkx2-5-cre)9Eno/?
Background: involves: 129S4/SvJae * BALB/c * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Swhtr/Swhtr
Background: either: (involves: C57BL/6J) or (involves: 129S6/SvEvTac * C57BL/6J * C57BL/6NTac)
Zygosity: hm
Has Mutant Allele: true
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GO Term
GO:1990664 | Nkx-2.5 complex
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DO Term
DOID:0070125 | congenital nongoitrous hypothyroidism 5
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Publication
19011045 | J:146335
First Author: Li X
Year: 2009
Journal: Am J Physiol Heart Circ Physiol
Title: Na+/H+ exchanger isoform 1 facilitates cardiomyocyte embryonic stem cell differentiation.
Volume: 296
Issue: 1
Pages: H159-70
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Publication
12270938 | J:80201
First Author: Zhang W
Year: 2002
Journal: J Biol Chem
Title: Regulation of Hex gene expression by a Smads-dependent signaling pathway.
Volume: 277
Issue: 47
Pages: 45435-41
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Publication
21554246 | J:177756
First Author: Yasuda S
Year: 2011
Journal: Biochem J
Title: AW551984: a novel regulator of cardiomyogenesis in pluripotent embryonic cells.
Volume: 437
Issue: 2
Pages: 345-55
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Publication
24584570 | J:210662
First Author: Beraldi R
Year: 2014
Journal: Hum Mol Genet
Title: Rbm20-deficient cardiogenesis reveals early disruption of RNA processing and sarcomere remodeling establishing a developmental etiology for dilated cardiomyopathy.
Volume: 23
Issue: 14
Pages: 3779-91
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Publication
19797053 | J:177245
First Author: Sun Q
Year: 2009
Journal: J Biol Chem
Title: Myocardin-dependent activation of the CArG box-rich smooth muscle gamma-actin gene: preferential utilization of a single CArG element through functional association with the NKX3.1 homeodomain protein.
Volume: 284
Issue: 47
Pages: 32582-90
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Publication
10656766 | J:60408
First Author: Griffin KJ
Year: 2000
Journal: Dev Biol
Title: A conserved role for H15-related T-box transcription factors in zebrafish and Drosophila heart formation.
Volume: 218
Issue: 2
Pages: 235-47
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Publication
9529161 | J:47080
First Author: Zilberman A
Year: 1998
Journal: Circ Res
Title: Evolutionarily conserved promoter region containing CArG*-like elements is crucial for smooth muscle myosin heavy chain gene expression.
Volume: 82
Issue: 5
Pages: 566-75
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Publication
10477291 | J:55608
First Author: Kuo H
Year: 1999
Journal: Development
Title: Control of segmental expression of the cardiac-restricted ankyrin repeat protein gene by distinct regulatory pathways in murine cardiogenesis.
Volume: 126
Issue: 19
Pages: 4223-34
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Publication
12590133 | J:83196
First Author: Rybkin II
Year: 2003
Journal: J Biol Chem
Title: Conditional expression of SV40 T-antigen in mouse cardiomyocytes facilitates an inducible switch from proliferation to differentiation.
Volume: 278
Issue: 18
Pages: 15927-34
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Publication
14573514 | J:87041
First Author: Takeuchi JK
Year: 2003
Journal: Development
Title: Tbx5 specifies the left/right ventricles and ventricular septum position during cardiogenesis.
Volume: 130
Issue: 24
Pages: 5953-64
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Publication
16165126 | J:102813
First Author: Stary M
Year: 2005
Journal: Exp Cell Res
Title: Parietal endoderm secreted SPARC promotes early cardiomyogenesis in vitro.
Volume: 310
Issue: 2
Pages: 331-43
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Publication
16699073 | J:116437
First Author: Chen Y
Year: 2006
Journal: Am J Physiol Heart Circ Physiol
Title: Vascular endothelial growth factor promotes cardiomyocyte differentiation of embryonic stem cells.
Volume: 291
Issue: 4
Pages: H1653-8
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Publication
19020077 | J:142358
First Author: Mujoo K
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Role of nitric oxide signaling components in differentiation of embryonic stem cells into myocardial cells.
Volume: 105
Issue: 48
Pages: 18924-9
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Publication
18832173 | J:143448
First Author: Boni A
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Notch1 regulates the fate of cardiac progenitor cells.
Volume: 105
Issue: 40
Pages: 15529-34
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Publication
19858210 | J:158192
First Author: Cho J
Year: 2009
Journal: J Biol Chem
Title: Distinct roles of glycogen synthase kinase (GSK)-3alpha and GSK-3beta in mediating cardiomyocyte differentiation in murine bone marrow-derived mesenchymal stem cells.
Volume: 284
Issue: 52
Pages: 36647-58
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Publication
23056302 | J:191938
First Author: Uosaki H
Year: 2012
Journal: PLoS One
Title: Direct contact with endoderm-like cells efficiently induces cardiac progenitors from mouse and human pluripotent stem cells.
Volume: 7
Issue: 10
Pages: e46413
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Publication
25091331 | J:216209
First Author: Roque-Ramírez B
Year: 2014
Journal: Dev Dyn
Title: Expression pattern of mRNA A and mRNA B of alpha sarcoglycan gene during mouse embryonic development and regulation of their expression by myogenic and cardiogenic transcription factors.
Volume: 243
Issue: 11
Pages: 1416-28
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Publication
28287249 | J:240168
First Author: Zheng B
Year: 2017
Journal: Int J Dev Biol
Title: mTORC1 and mTORC2 play different roles in regulating cardiomyocyte differentiation from embryonic stem cells.
Volume: 61
Issue: 1-2
Pages: 65-72
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Publication
26565625 | J:243812
First Author: Zafir A
Year: 2015
Journal: PLoS One
Title: O-GlcNAcylation Negatively Regulates Cardiomyogenic Fate in Adult Mouse Cardiac Mesenchymal Stromal Cells.
Volume: 10
Issue: 11
Pages: e0142939
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Publication
33212270 | J:305761
 
First Author: Ahmed A
Year: 2021
Journal: Mol Metab
Title: Maternal obesity persistently alters cardiac progenitor gene expression and programs adult-onset heart disease susceptibility.
Volume: 43
Pages: 101116
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Publication
33763067 | J:307538
 
First Author: Yonebayashi S
Year: 2021
Journal: Front Immunol
Title: Generation of Transgenic Mice that Conditionally Overexpress Tenascin-C.
Volume: 12
Pages: 620541
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Publication
32863954 | J:313367
First Author: Miao S
Year: 2020
Journal: Theranostics
Title: Retinoic acid promotes metabolic maturation of human Embryonic Stem Cell-derived Cardiomyocytes.
Volume: 10
Issue: 21
Pages: 9686-9701
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Publication
24847033 | J:320517
First Author: Liu H
Year: 2014
Journal: J Am Heart Assoc
Title: Phosphorylation of Shox2 is required for its function to control sinoatrial node formation.
Volume: 3
Issue: 3
Pages: e000796
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Publication
23818299 | J:320848
First Author: Zheng G
Year: 2013
Journal: Stem Cells
Title: Brief report: SRF-dependent MiR-210 silences the sonic hedgehog signaling during cardiopoesis.
Volume: 31
Issue: 10
Pages: 2279-85
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Publication
9621432 | J:330693
First Author: Durocher D
Year: 1998
Journal: Dev Genet
Title: Combinatorial interactions regulating cardiac transcription.
Volume: 22
Issue: 3
Pages: 250-62
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GXD Expression
GXD Expression
   
Probe: MGI:3027117
Assay Type: Northern blot
Annotation Date: 2004-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610515
Stage: TS15
Assay Id: MGI:3027119
Age: embryonic day 9.5
Image: 1
Specimen Label: Nkx2.5 +/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:3027117
Assay Type: Northern blot
Annotation Date: 2004-02-09
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610515
Stage: TS15
Assay Id: MGI:3027119
Age: embryonic day 9.5
Image: 1
Specimen Label: Nkx2.5 -/-
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:3027117
Assay Type: Northern blot
Annotation Date: 2004-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610517
Stage: TS17
Assay Id: MGI:3027119
Age: embryonic day 10.5
Image: 1
Specimen Label: Nkx2.5 +/+
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:3027117
Assay Type: Northern blot
Annotation Date: 2004-02-09
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610517
Stage: TS17
Assay Id: MGI:3027119
Age: embryonic day 10.5
Image: 1
Specimen Label: Nkx2.5 -/-
Detected: false
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6423559
Assay Type: RT-PCR
Annotation Date: 2020-05-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610514
Stage: TS14
Assay Id: MGI:6423705
Age: embryonic day 9.0
Image: S4
Specimen Label: Nkx2-5 KO
Detected: true
Specimen Num: 2
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Genotype
Genotype
Symbol: Mir128-2/Mir128-2 Tg(Nkx2-5-cre)9Eno/?
Background: involves: C57BL/6N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Nkx2-5-cre)9Eno/?
Background: involves: 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Smarca4/Smarca4 Tg(Nkx2-5-cre)9Eno/?
Background: involves: 129S2/SvPas
Zygosity: cn
Has Mutant Allele: true
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GXD Expression
GXD Expression
 
Probe: MGI:3829266
Assay Type: Immunohistochemistry
Annotation Date: 2009-01-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1636115
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:3829275
Age: embryonic day 9.5
Note: Authors report a reduction in the number of expressing cells compared with wild type.
Specimen Label: Nkx2-5 -/- (middle)
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:3829266
Assay Type: Immunohistochemistry
Annotation Date: 2009-01-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1636115
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:3829275
Age: embryonic day 9.5
Note: Authors report a reduction in the number of expressing cells compared with wild type.
Specimen Label: Nkx2-5 -/- (top)
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:3829268
Assay Type: Immunohistochemistry
Annotation Date: 2009-01-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1636115
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:3829276
Age: embryonic day 9.5
Note: Authors report a reduction in the number of expressing cells compared with wild type.
Specimen Label: Nkx2-5 -/- (middle)
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:3829268
Assay Type: Immunohistochemistry
Annotation Date: 2009-01-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1636115
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:3829276
Age: embryonic day 9.5
Note: Authors report a reduction in the number of expressing cells compared with wild type.
Specimen Label: Nkx2-5 -/- (top)
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:3829270
Assay Type: Immunohistochemistry
Annotation Date: 2009-01-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1636115
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:3829277
Age: embryonic day 9.5
Note: Authors report a reduction in the number of expressing cells compared with wild type.
Specimen Label: Nkx2-5 -/- (middle)
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:3829270
Assay Type: Immunohistochemistry
Annotation Date: 2009-01-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1636115
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:3829277
Age: embryonic day 9.5
Note: Authors report a reduction in the number of expressing cells compared with wild type.
Specimen Label: Nkx2-5 -/- (top)
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:6116657
Assay Type: RNA in situ
Annotation Date: 2018-02-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610515
Pattern: Graded
Stage: TS15
Assay Id: MGI:6116672
Age: embryonic day 9.5
Image: 2D Nkx2.5-/-
Note: Both overall levels of expression and caudal-high gradient appeared normal in Nkx2-5 null embryos.
Specimen Label: 2D Nkx2.5-/-
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
Probe: MGI:6444239
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1618217
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:6444470
Age: embryonic day 10.5
Image: 3A
Note: Tfap2a and Nkx2-5 were not co-expressed.
Specimen Label: 3A
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:6444239
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1618217
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:6444470
Age: embryonic day 10.5
Image: 3D
Note: Tfap2a and Nkx2-5 were not co-expressed.
Specimen Label: 3D
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:6444239
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1618219
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6444470
Age: embryonic day 11.5
Image: 3B/C
Note: Tfap2a and Nkx2-5 were not co-expressed.
Specimen Label: 3B/C
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:6444239
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1618219
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6444470
Age: embryonic day 11.5
Image: 3E/F
Note: Tfap2a and Nkx2-5 were not co-expressed.
Specimen Label: 3E/F
Detected: true
Specimen Num: 4
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Genotype
Genotype
Symbol: Tg(NKX2-5-EmGFP)2Conk/?
Background: involves: 129P2/OlaHsd
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Nkx2-5-cre)9Eno/?
Background: involves: 129S4/SvJaeSor * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Itgb1/Itgb1 Tg(Nkx2-5-cre)9Eno/?
Background: involves: 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Casp3/Casp3 Casp7/Casp7 Tg(Nkx2-5-cre)9Eno/?
Background: involves: 129S6/SvEvTac * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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HT Experiment
E-GEOD-78 | Transcription profiling of mouse heart from embryonic day 9.5 from Nkx2.5 deleted mice, Nkx.5 is a mouse model of congenital heart disease
Series Id: GSE78
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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HT Experiment
E-GEOD-7343 | Dicer conditional knockout embryonic heart mutant vs control array
Series Id: GSE7343
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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HT Experiment
E-GEOD-31583 | Lung of ECAT15-2/Dppa2 deficient embryo at E18.5
Series Id: GSE31583
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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HT Experiment
E-GEOD-27259 | Cardiac gene expression profiling of Salvador mutant mice
Series Id: GSE27259
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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HT Experiment
E-GEOD-52080 | Transcriptome of Nkx2-5-null atria
Series Id: GSE52080
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: ArrayExpress
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HT Experiment
GSE98579 | RNAseq for Tfam knock under NKX2.5 promoter
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE135152 | Rbfox2 is necessary for cardiovascular development
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE164453 | Gene expression profiling of Hif1alpha defective hearts in E12.5 mice
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE108879 | Single-cell transcriptomic analysis reveals lineage hierarcies and communications for second heart lineage deployment [RNA-seq]
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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HT Experiment
GSE63796 | Single cell expression profiles of the earliest cardiac precursor cells
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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HT Experiment
GSE114532 | Mechanism sharing between genetic and gestational hypoxia-induced cardiac anomalies
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE124008 | A reference map of cardiac transcription factor chromatin occupancy identifies dynamic and conserved transcriptional enhancers
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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HT Experiment
GSE128571 | E11.5 Hand1 myocardial knockout RNA-Seq
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Sample
Nkx2-2 NULL Embryos Rep5
 
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 13.5
Stage: 21
Structure . Name: pancreas
Curation Status: Curated
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HT Sample
GSM1557539
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 7.0
Stage: 10
Structure . Name: embryo mesoderm
Notes: Nkx2-5 positive cell from an early allantoic bud stage embryo
Curation Status: Curated
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HT Sample
GSM1557540
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 7.0
Stage: 10
Structure . Name: embryo mesoderm
Notes: Nkx2-5 positive cell from an early allantoic bud stage embryo
Curation Status: Curated
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HT Sample
GSM1557541
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 7.0
Stage: 10
Structure . Name: embryo mesoderm
Notes: Nkx2-5 positive cell from an early allantoic bud stage embryo
Curation Status: Curated
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HT Sample
GSM1557545
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 7.5
Stage: 11
Structure . Name: cardiogenic plate
Notes: Nkx2-5 positive cell from an early headfold stage embryo
Curation Status: Curated
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HT Sample
GSM1557546
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 7.5
Stage: 11
Structure . Name: cardiogenic plate
Notes: Nkx2-5 positive cell from an early headfold stage embryo
Curation Status: Curated
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HT Sample
GSM1557547
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 7.5
Stage: 11
Structure . Name: cardiogenic plate
Notes: Nkx2-5 positive cell from an early headfold stage embryo
Curation Status: Curated
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HT Sample
GSM1557548
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 7.5
Stage: 11
Structure . Name: cardiogenic plate
Notes: Nkx2-5/Tbx5 positive cell from an early headfold stage embryo
Curation Status: Curated
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HT Sample
GSM1557549
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 7.5
Stage: 11
Structure . Name: cardiogenic plate
Notes: Nkx2-5/Tbx5 positive cell from an early headfold stage embryo
Curation Status: Curated
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•
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HT Sample
GSM1557550
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 7.5
Stage: 11
Structure . Name: cardiogenic plate
Notes: Nkx2-5/Tbx5 positive cell from an early headfold stage embryo
Curation Status: Curated
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Interaction Experiment
Risebro CA (2012)
Description: Epistatic Rescue of Nkx2.5 Adult Cardiac Conduction Disease Phenotypes by Prospero-Related Homeobox Protein 1 and HDAC3.
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Interaction Experiment
Nimura K (2009)
Description: A histone H3 lysine 36 trimethyltransferase links Nkx2-5 to Wolf-Hirschhorn syndrome.
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Interaction Experiment
Vincentz JW (2008)
Description: Cooperative interaction of Nkx2.5 and Mef2c transcription factors during heart development.
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Interaction Detail
Interaction Detail
   
Role 2: prey
Type: physical
Role 1: bait
Name: Nkx2-5-Tbx5
Relationship Type: direct interaction
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Interaction Detail
Interaction Detail
   
Role 2: bait
Type: physical
Role 1: prey
Name: Nkx2-5-Tbx5
Relationship Type: direct interaction
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Interaction Detail
Interaction Detail
   
Role 2: prey
Type: physical
Role 1: bait
Name: Nkx2-5-Fbxo25
Relationship Type: physical association
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Interaction Experiment
Jeong HS (2015)
Description: Fbxo25 controls Tbx5 and Nkx2-5 transcriptional activity to regulate cardiomyocyte development.
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Interaction Detail
Interaction Detail
   
Role 2: bait
Type: physical
Role 1: prey
Name: Nkx2-5-Fbxo25
Relationship Type: physical association
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