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Search results 1701 to 1800 out of 2424 for Ran

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Hits by Strain

Type Details Score
Genotype
Symbol: Ranbp2/Ranbp2<+>
Background: C57BL/6N-Ranbp2/MbpMmucd
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Ranbp10/Ranbp10<+>
Background: C57BL/6N-Ranbp10/Ucd
Zygosity: ht
Has Mutant Allele: true
Publication
First Author: Schwärzler J
Year: 2022
Journal: Gastroenterology
Title: PUFA-Induced Metabolic Enteritis as a Fuel for Crohn's Disease.
Volume: 162
Issue: 6
Pages: 1690-1704
Publication
First Author: Paduch M
Year: 2001
Journal: Acta Biochim Pol
Title: Structure of small G proteins and their regulators.
Volume: 48
Issue: 4
Pages: 829-50
Publication
First Author: Yant LJ
Year: 2003
Journal: Free Radic Biol Med
Title: The selenoprotein GPX4 is essential for mouse development and protects from radiation and oxidative damage insults.
Volume: 34
Issue: 4
Pages: 496-502
Publication
First Author: Zhou Q
Year: 2014
Journal: Cell Host Microbe
Title: The ER-associated protein ZDHHC1 is a positive regulator of DNA virus-triggered, MITA/STING-dependent innate immune signaling.
Volume: 16
Issue: 4
Pages: 450-61
Publication
First Author: Li Y
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: ISG56 is a negative-feedback regulator of virus-triggered signaling and cellular antiviral response.
Volume: 106
Issue: 19
Pages: 7945-50
Publication
First Author: Nishimasu H
Year: 2014
Journal: Cell
Title: Crystal structure of Cas9 in complex with guide RNA and target DNA.
Volume: 156
Issue: 5
Pages: 935-49
Publication
First Author: Yamada M
Year: 2017
Journal: Mol Cell
Title: Crystal Structure of the Minimal Cas9 from Campylobacter jejuni Reveals the Molecular Diversity in the CRISPR-Cas9 Systems.
Volume: 65
Issue: 6
Pages: 1109-1121.e3
Publication
First Author: Zhou Q
Year: 2017
Journal: Biochim Biophys Acta
Title: Dihydromyricetin prevents obesity-induced slow-twitch-fiber reduction partially via FLCN/FNIP1/AMPK pathway.
Volume: 1863
Issue: 6
Pages: 1282-1291
Publication
First Author: Guo Z
Year: 2008
Journal: Free Radic Biol Med
Title: Suppression of atherogenesis by overexpression of glutathione peroxidase-4 in apolipoprotein E-deficient mice.
Volume: 44
Issue: 3
Pages: 343-52
Publication
First Author: Sun Y
Year: 2010
Journal: Hum Mol Genet
Title: Specific saposin C deficiency: CNS impairment and acid beta-glucosidase effects in the mouse.
Volume: 19
Issue: 4
Pages: 634-47
Publication
First Author: Dong Z
Year: 2013
Journal: PLoS One
Title: Urea transporter UT-B deletion induces DNA damage and apoptosis in mouse bladder urothelium.
Volume: 8
Issue: 10
Pages: e76952
Publication
First Author: Ren H
Year: 2014
Journal: Am J Physiol Renal Physiol
Title: Thienoquinolins exert diuresis by strongly inhibiting UT-A urea transporters.
Volume: 307
Issue: 12
Pages: F1363-72
Publication
First Author: Bhattacharya A
Year: 2009
Journal: J Biol Chem
Title: Denervation induces cytosolic phospholipase A2-mediated fatty acid hydroperoxide generation by muscle mitochondria.
Volume: 284
Issue: 1
Pages: 46-55
Publication
First Author: Guo L
Year: 2020
Journal: Nat Commun
Title: PINCH-1 regulates mitochondrial dynamics to promote proline synthesis and tumor growth.
Volume: 11
Issue: 1
Pages: 4913
Publication
First Author: Liu TT
Year: 2016
Journal: J Immunol
Title: LSm14A Plays a Critical Role in Antiviral Immune Responses by Regulating MITA Level in a Cell-Specific Manner.
Volume: 196
Issue: 12
Pages: 5101-11
Publication
First Author: Liou B
Year: 2019
Journal: Sci Rep
Title: Combination of acid β-glucosidase mutation and Saposin C deficiency in mice reveals Gba1 mutation dependent and tissue-specific disease phenotype.
Volume: 9
Issue: 1
Pages: 5571
Publication
First Author: Zhang X
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Near-infrared fluorescence molecular imaging of amyloid beta species and monitoring therapy in animal models of Alzheimer's disease.
Volume: 112
Issue: 31
Pages: 9734-9
Publication
First Author: Cao K
Year: 2019
Journal: Alzheimers Res Ther
Title: Exposure to fluoride aggravates the impairment in learning and memory and neuropathological lesions in mice carrying the APP/PS1 double-transgenic mutation.
Volume: 11
Issue: 1
Pages: 35
Publication  
First Author: Guo J
Year: 2021
Journal: EBioMedicine
Title: Cell-type-specific imaging of neurotransmission reveals a disrupted excitatory-inhibitory cortical network in isoflurane anaesthesia.
Volume: 65
Pages: 103272
Publication
First Author: Zhang Z
Year: 2023
Journal: Nat Immunol
Title: Distinct changes in endosomal composition promote NLRP3 inflammasome activation.
Volume: 24
Issue: 1
Pages: 30-41
Publication
First Author: Havrda MC
Year: 2014
Journal: Cancer Res
Title: Id2 mediates oligodendrocyte precursor cell maturation arrest and is tumorigenic in a PDGF-rich microenvironment.
Volume: 74
Issue: 6
Pages: 1822-32
Publication  
First Author: Chang L
Year: 2023
Journal: Front Cell Neurosci
Title: Spike desensitisation as a mechanism for high-contrast selectivity in retinal ganglion cells.
Volume: 17
Pages: 1337768
Publication
First Author: Clark K
Year: 2006
Journal: EMBO J
Title: TRPM7, a novel regulator of actomyosin contractility and cell adhesion.
Volume: 25
Issue: 2
Pages: 290-301
Publication
First Author: Zusman T
Year: 1996
Journal: Int J Cancer
Title: Contribution of the intracellular domain of murine Fc-gamma receptor type IIB1 to its tumor-enhancing potential.
Volume: 68
Issue: 2
Pages: 219-27
Publication
First Author: Yan B
Year: 2014
Journal: PLoS One
Title: HDAC6 deacetylase activity is critical for lipopolysaccharide-induced activation of macrophages.
Volume: 9
Issue: 10
Pages: e110718
Publication
First Author: Zhu L
Year: 2019
Journal: Am J Respir Cell Mol Biol
Title: The Club Cell Marker SCGB1A1 Downstream of FOXA2 is Reduced in Asthma.
Volume: 60
Issue: 6
Pages: 695-704
Publication
First Author: Li WW
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Ubiquitination of TLR3 by TRIM3 signals its ESCRT-mediated trafficking to the endolysosomes for innate antiviral response.
Volume: 117
Issue: 38
Pages: 23707-23716
Publication
First Author: Liu J
Year: 2016
Journal: Cell Signal
Title: Repulsive guidance molecule b inhibits renal cyst development through the bone morphogenetic protein signaling pathway.
Volume: 28
Issue: 12
Pages: 1842-1851
Publication  
First Author: Sun Y
Year: 2008
Journal: BMC Neurosci
Title: Temporal gene expression profiling reveals CEBPD as a candidate regulator of brain disease in prosaposin deficient mice.
Volume: 9
Pages: 76
GO Term
Allele
Name: importin 13; gene trap XS0873, Wellcome Trust Sanger Institute
Allele Type: Gene trapped
Attribute String: Null/knockout, Reporter
Publication
First Author: Di Fiore B
Year: 2003
Journal: J Cell Sci
Title: Mammalian RanBP1 regulates centrosome cohesion during mitosis.
Volume: 116
Issue: Pt 16
Pages: 3399-411
HT Experiment  
Experiment Type: RNA-Seq
Study Type: Baseline
Source: ArrayExpress
GXD Expression  
Probe: MGI:1330766
Assay Type: Immunohistochemistry
Annotation Date: 2024-11-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1698920
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:7764914
Age: embryonic day 12.5
Note: The ramus dorsalis turned dorsolaterally and formed muscle branches to the dorsal muscle groups and skin sensory rami in a highly segmental pattern. The rami ventralis ran ventrally and sprouted the lateral cutaneous branches toward the lateral body wall. No nerve fibers crossed the dorsal midline.
Specimen Label: 3G
Detected: true
Specimen Num: 12
GO Term
GO Term
Publication
First Author: Xu C
Year: 2021
Journal: Cell Rep
Title: The glutathione peroxidase Gpx4 prevents lipid peroxidation and ferroptosis to sustain Treg cell activation and suppression of antitumor immunity.
Volume: 35
Issue: 11
Pages: 109235
Strain
Attribute String: mutant strain, coisogenic, targeted mutation
Strain
Attribute String: mutant strain, coisogenic, targeted mutation
Genotype
Symbol: Ranbp2/Ranbp2<+>
Background: involves: 129/Sv * C57BL/6
Zygosity: ht
Has Mutant Allele: true
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Itier JM
Year: 1998
Journal: Nature
Title: Imprinted gene in postnatal growth role.
Volume: 393
Issue: 6681
Pages: 125-6
Publication  
First Author: Kim DH
Year: 2016
Journal: Nat Commun
Title: Critical role of RanBP2-mediated SUMOylation of Small Heterodimer Partner in maintaining bile acid homeostasis.
Volume: 7
Pages: 12179
Publication  
First Author: Ritterhoff T
Year: 2016
Journal: Nat Commun
Title: The RanBP2/RanGAP1*SUMO1/Ubc9 SUMO E3 ligase is a disassembly machine for Crm1-dependent nuclear export complexes.
Volume: 7
Pages: 11482
Publication
First Author: Cai Y
Year: 2001
Journal: J Biol Chem
Title: The docking of kinesins, KIF5B and KIF5C, to Ran-binding protein 2 (RanBP2) is mediated via a novel RanBP2 domain.
Volume: 276
Issue: 45
Pages: 41594-602
Publication
First Author: Scapoli L
Year: 2010
Journal: Hum Mutat
Title: Expression and association data strongly support JARID2 involvement in nonsyndromic cleft lip with or without cleft palate.
Volume: 31
Issue: 7
Pages: 794-800
Publication
First Author: Gloerich M
Year: 2011
Journal: J Cell Biol
Title: The nucleoporin RanBP2 tethers the cAMP effector Epac1 and inhibits its catalytic activity.
Volume: 193
Issue: 6
Pages: 1009-20
Publication
First Author: Bidinosti M
Year: 2010
Journal: Mol Cell
Title: Postnatal deamidation of 4E-BP2 in brain enhances its association with raptor and alters kinetics of excitatory synaptic transmission.
Volume: 37
Issue: 6
Pages: 797-808
Publication
First Author: Foks AC
Year: 2013
Journal: Arterioscler Thromb Vasc Biol
Title: T-cell immunoglobulin and mucin domain 3 acts as a negative regulator of atherosclerosis.
Volume: 33
Issue: 11
Pages: 2558-65
Publication
First Author: Westerlund M
Year: 2008
Journal: Mol Cell Neurosci
Title: Lrrk2 and alpha-synuclein are co-regulated in rodent striatum.
Volume: 39
Issue: 4
Pages: 586-91
Publication
First Author: Yao ST
Year: 2017
Journal: J Mol Neurosci
Title: NLRP3 is Required for Complement-Mediated Caspase-1 and IL-1beta Activation in ICH.
Volume: 61
Issue: 3
Pages: 385-395
Publication
First Author: Sun Y
Year: 2008
Journal: Hum Mol Genet
Title: Neurological deficits and glycosphingolipid accumulation in saposin B deficient mice.
Volume: 17
Issue: 15
Pages: 2345-56
Publication
First Author: Sun Y
Year: 2013
Journal: Hum Mol Genet
Title: Tissue-specific effects of saposin A and saposin B on glycosphingolipid degradation in mutant mice.
Volume: 22
Issue: 12
Pages: 2435-50
Publication
First Author: Qiao L
Year: 2022
Journal: Cell Death Dis
Title: Hepatic deficiency of selenoprotein S exacerbates hepatic steatosis and insulin resistance.
Volume: 13
Issue: 3
Pages: 275
Publication
First Author: Anvret A
Year: 2012
Journal: Behav Brain Res
Title: Adh1 and Adh1/4 knockout mice as possible rodent models for presymptomatic Parkinson's disease.
Volume: 227
Issue: 1
Pages: 252-7
Publication
First Author: Zhang C
Year: 2018
Journal: Sci Rep
Title: Cromolyn Reduces Levels of the Alzheimer's Disease-Associated Amyloid β-Protein by Promoting Microglial Phagocytosis.
Volume: 8
Issue: 1
Pages: 1144
Publication  
First Author: Hu X
Year: 2015
Journal: Sci Rep
Title: Deletion of the tyrosine phosphatase Shp2 in Sertoli cells causes infertility in mice.
Volume: 5
Pages: 12982
Publication
First Author: Sun Y
Year: 2014
Journal: Mol Genet Metab
Title: Reversal of advanced disease in lysosomal acid lipase deficient mice: a model for lysosomal acid lipase deficiency disease.
Volume: 112
Issue: 3
Pages: 229-41
Publication
First Author: Liang H
Year: 2009
Journal: Free Radic Biol Med
Title: Glutathione peroxidase 4 differentially regulates the release of apoptogenic proteins from mitochondria.
Volume: 47
Issue: 3
Pages: 312-20
Publication  
First Author: Chen G
Year: 2018
Journal: Front Immunol
Title: G Protein-Coupled Receptor 109A and Host Microbiota Modulate Intestinal Epithelial Integrity During Sepsis.
Volume: 9
Pages: 2079
Publication
First Author: Tu Z
Year: 2016
Journal: Cell Death Differ
Title: Uterine RAC1 via Pak1-ERM signaling directs normal luminal epithelial integrity conducive to on-time embryo implantation in mice.
Volume: 23
Issue: 1
Pages: 169-81
Publication  
First Author: Wang W
Year: 2021
Journal: Biochem Biophys Res Commun
Title: CX3CR1 deficiency aggravates brain white matter injury and affects expression of the CD36/15LO/NR4A1 signal.
Volume: 549
Pages: 47-53
Publication
First Author: Sun Y
Year: 2010
Journal: Hum Mol Genet
Title: Neuronopathic Gaucher disease in the mouse: viable combined selective saposin C deficiency and mutant glucocerebrosidase (V394L) mice with glucosylsphingosine and glucosylceramide accumulation and progressive neurological deficits.
Volume: 19
Issue: 6
Pages: 1088-97
Publication
First Author: Lin D
Year: 2014
Journal: Endocrinology
Title: Abnormal response to the anorexic effect of GHS-R inhibitors and exenatide in male Snord116 deletion mouse model for Prader-Willi syndrome.
Volume: 155
Issue: 7
Pages: 2355-62
Publication
First Author: Xiang J
Year: 2021
Journal: J Cell Mol Med
Title: LiCl attenuates impaired learning and memory of APP/PS1 mice, which in mechanism involves α7 nAChRs and Wnt/β-catenin pathway.
Volume: 25
Issue: 22
Pages: 10698-10710
Publication
First Author: Zhi JJ
Year: 2023
Journal: J Neurosci
Title: Insufficient Oligodendrocyte Turnover in Optic Nerve Contributes to Age-Related Axon Loss and Visual Deficits.
Volume: 43
Issue: 11
Pages: 1859-1870
Publication
First Author: Yang Y
Year: 2014
Journal: Cell Res
Title: CYLD mediates ciliogenesis in multiple organs by deubiquitinating Cep70 and inactivating HDAC6.
Volume: 24
Issue: 11
Pages: 1342-53
Publication
First Author: Yang S
Year: 2021
Journal: J Clin Lab Anal
Title: CYLD deficiency causes auditory neuropathy due to reduced neurite outgrowth.
Volume: 35
Issue: 6
Pages: e23783
Publication  
First Author: Mitra A
Year: 2020
Journal: Front Immunol
Title: CD28 Signaling Drives Notch Ligand Expression on CD4 T Cells.
Volume: 11
Pages: 735
Publication
First Author: Feng J
Year: 2023
Journal: Invest Ophthalmol Vis Sci
Title: Loss of TRPM8 Exacerbate Herpes Simplex Keratitis Infection in Mice by Promoting the Infiltration of CD11b+ Ly6G+ Cells and Increasing the Viral Load in the Cornea.
Volume: 64
Issue: 15
Pages: 24
Publication
First Author: Gelegen C
Year: 2018
Journal: Curr Biol
Title: Excitatory Pathways from the Lateral Habenula Enable Propofol-Induced Sedation.
Volume: 28
Issue: 4
Pages: 580-587.e5
Publication
First Author: Jain A
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: CRISPR-Cas9-based treatment of myocilin-associated glaucoma.
Volume: 114
Issue: 42
Pages: 11199-11204
Publication  
First Author: Li Y
Year: 2024
Journal: Biochem Biophys Res Commun
Title: TSHR signaling promotes hippocampal dependent memory formation through modulating Wnt5a/β-catenin mediated neurogenesis.
Volume: 704
Pages: 149723
Publication
First Author: Liu X
Year: 2018
Journal: Eur J Oral Sci
Title: Inactivation of Fam20b in the neural crest-derived mesenchyme of mouse causes multiple craniofacial defects.
Volume: 126
Issue: 5
Pages: 433-436
Publication
First Author: Zhao N
Year: 2021
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Neutrophils-derived Spink7 as one safeguard against experimental murine colitis.
Volume: 1867
Issue: 6
Pages: 166125
Publication
First Author: Li H
Year: 2024
Journal: Nature
Title: AARS1 and AARS2 sense L-lactate to regulate cGAS as global lysine lactyltransferases.
Volume: 634
Issue: 8036
Pages: 1229-1237
Publication
First Author: Song T
Year: 2022
Journal: EMBO Rep
Title: ENKD1 promotes CP110 removal through competing with CEP97 to initiate ciliogenesis.
Volume: 23
Issue: 5
Pages: e54090
Publication
First Author: Li P
Year: 2021
Journal: Aging (Albany NY)
Title: Piccolo is essential for the maintenance of mouse retina but not cochlear hair cell function.
Volume: 13
Issue: 8
Pages: 11678-11695
Publication  
First Author: Lessard CB
Year: 2018
Journal: EMBO Mol Med
Title: High-affinity interactions and signal transduction between Aβ oligomers and TREM2.
Volume: 10
Issue: 11
Publication
First Author: Wang T
Year: 2012
Journal: Am J Pathol
Title: miR-21 regulates skin wound healing by targeting multiple aspects of the healing process.
Volume: 181
Issue: 6
Pages: 1911-20
Publication
First Author: Chen L
Year: 2008
Journal: Aging Cell
Title: Reduction of mitochondrial H2O2 by overexpressing peroxiredoxin 3 improves glucose tolerance in mice.
Volume: 7
Issue: 6
Pages: 866-78
Publication
First Author: Wang J
Year: 2015
Journal: Cardiovasc Res
Title: Hypoxia inducible factor-1-dependent up-regulation of BMP4 mediates hypoxia-induced increase of TRPC expression in PASMCs.
Volume: 107
Issue: 1
Pages: 108-18
Publication
First Author: Li MG
Year: 2018
Journal: J Immunol
Title: Bcl2L12 Contributes to Th2-Biased Inflammation in the Intestinal Mucosa by Regulating CD4+ T Cell Activities.
Volume: 201
Issue: 2
Pages: 725-733
Publication
First Author: Xu ZS
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: FAM64A positively regulates STAT3 activity to promote Th17 differentiation and colitis-associated carcinogenesis.
Volume: 116
Issue: 21
Pages: 10447-10452
Publication
First Author: Zheng PY
Year: 2019
Journal: Theranostics
Title: Regulating Bcl2L12 expression in mast cells inhibits food allergy.
Volume: 9
Issue: 17
Pages: 4982-4992
Publication
First Author: Kitahara A
Year: 2020
Journal: Cell Rep
Title: Generation of Lungs by Blastocyst Complementation in Apneumic Fgf10-Deficient Mice.
Volume: 31
Issue: 6
Pages: 107626
Publication
First Author: Zhou J
Year: 2020
Journal: FASEB J
Title: Hepatocyte nuclear factor 4α negatively regulates connective tissue growth factor during liver regeneration.
Volume: 34
Issue: 4
Pages: 4970-4983
Publication
First Author: Yang C
Year: 2021
Journal: Commun Biol
Title: Melatonin delays ovarian aging in mice by slowing down the exhaustion of ovarian reserve.
Volume: 4
Issue: 1
Pages: 534
Publication  
First Author: Zhang J
Year: 2020
Journal: Mol Immunol
Title: MiR-26a targets EphA2 to resist intracellular Listeria monocytogenes in macrophages.
Volume: 128
Pages: 69-78
Publication  
First Author: das Dores Pereira R
Year: 2021
Journal: Cell Immunol
Title: Role of formyl peptide receptor 2 (FPR2) in modulating immune response and heart inflammation in an experimental model of acute and chronic Chagas disease.
Volume: 369
Pages: 104427
Publication
First Author: Ahn B
Year: 2022
Journal: Aging Cell
Title: Scavenging mitochondrial hydrogen peroxide by peroxiredoxin 3 overexpression attenuates contractile dysfunction and muscle atrophy in a murine model of accelerated sarcopenia.
Volume: 21
Issue: 3
Pages: e13569
Publication
First Author: Lan Q
Year: 2022
Journal: J Thromb Haemost
Title: Renal Klotho safeguards platelet lifespan in advanced chronic kidney disease through restraining Bcl-xL ubiquitination and degradation.
Volume: 20
Issue: 12
Pages: 2972-2987
HT Experiment
Series Id: GSE77720
Experiment Type: RNA-Seq
Study Type: Baseline
Source: ArrayExpress
Publication
First Author: Fujiwara K
Year: 2016
Journal: Genes Cells
Title: Terminal differentiation of cortical neurons rapidly remodels RanGAP-mediated nuclear transport system.
Volume: 21
Issue: 11
Pages: 1176-1194
GO Term
GO Term
GO Term