MouseMine: Keyword Search

Protein Domain

Type:	Family
Description:	A number of protein families resemble HPr kinase (see ) but do not belong to that system. They include this family, which appears instead to be the marker for a different type of gene neighbourhood, in which one of the conserved neighbouring proteins resembles (but is distinct from) PqqD.

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Protein Domain

IPR011282 | 2am3keto_CoA_ligase

Type:	Family
Description:	2-amino-3-ketobutyrate coenzyme A ligase (KBL), also called glycine C-acetyltransferase, is a pyridoxal phosphate (PLP) dependent enzyme that catalyses the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA, the second step in the conversion of L-threonine to glycine in both prokaryotes and eukaryotes [, ].

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Protein Domain

IPR045008 | ACX4-like

Type:	Family
Description:	This entry represents a group of acyl-CoA dehydrogenases from bacteria and plants, including acyl-coenzyme A oxidase 4 (ACX4) from Arabidopsis. ACX4 catalyses the desaturation of short-chain acyl-CoAs to 2-trans-enoyl-CoAs in plant peroxisomes [, ]. It is essential for embryo development []and is required for nuclear histone acetylation and DNA demethylation at some endogenous genomic loci [].

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Publication

21270055 | J:169137

First Author:	Xu B
Year:	2011
Journal:	Development
Title:	Smad1 and its target gene Wif1 coordinate BMP and Wnt signaling activities to regulate fetal lung development.
Volume:	138
Issue:	5
Pages:	925-35

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Publication

17615242 | J:123150

First Author:	Ravindran R
Year:	2007
Journal:	Proc Natl Acad Sci U S A
Title:	CCR6-dependent recruitment of blood phagocytes is necessary for rapid CD4 T cell responses to local bacterial infection.
Volume:	104
Issue:	29
Pages:	12075-80

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Publication

28566287 | J:247040

First Author:	Nakatsu Y
Year:	2017
Journal:	J Biol Chem
Title:	The prolyl isomerase Pin1 increases β-cell proliferation and enhances insulin secretion.
Volume:	292
Issue:	28
Pages:	11886-11895

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HT Experiment

GSE176171 | A single cell atlas of human adipose tissue


Experiment Type:	RNA-Seq
Study Type:	Baseline
Source:	GEO

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Publication

2494666 | J:132265

First Author:	Durdik J
Year:	1989
Journal:	Proc Natl Acad Sci U S A
Title:	Isotype switching by a microinjected mu immunoglobulin heavy chain gene in transgenic mice.
Volume:	86
Issue:	7
Pages:	2346-50

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Publication

28972012 | J:251894

First Author:	Jain R
Year:	2017
Journal:	Blood
Title:	A critical epithelial survival axis regulated by MCL-1 maintains thymic function in mice.
Volume:	130
Issue:	23
Pages:	2504-2515

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Publication

28835451 | J:248970

First Author:	Yao L
Year:	2017
Journal:	Am J Physiol Regul Integr Comp Physiol
Title:	Obesity-induced vascular inflammation involves elevated arginase activity.
Volume:	313
Issue:	5
Pages:	R560-R571

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Publication

15618289 | J:97181

First Author:	Newhall KJ
Year:	2005
Journal:	Mol Endocrinol
Title:	Deletion of the RIIbeta-subunit of protein kinase A decreases body weight and increases energy expenditure in the obese, leptin-deficient ob/ob mouse.
Volume:	19
Issue:	4
Pages:	982-91

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Publication

28526921 | J:244241

First Author:	Kawamori D
Year:	2017
Journal:	Diabetologia
Title:	GLP-1 signalling compensates for impaired insulin signalling in regulating beta cell proliferation in βIRKO mice.
Volume:	60
Issue:	8
Pages:	1442-1453

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Publication

11862406 | J:75277

First Author:	Silveira PA
Year:	2001
Journal:	Immunogenetics
Title:	Identification of the Gasa3 and Gasa4 autoimmune gastritis susceptibility genes using congenic mice and partitioned, segregative and interaction analyses.
Volume:	53
Issue:	9
Pages:	741-50

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Publication

18201976 | J:133935

First Author:	Mishra A
Year:	2008
Journal:	J Biol Chem
Title:	E6-AP promotes misfolded polyglutamine proteins for proteasomal degradation and suppresses polyglutamine protein aggregation and toxicity.
Volume:	283
Issue:	12
Pages:	7648-56

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Publication

22606265 | J:187244

First Author:	Kirov A
Year:	2012
Journal:	PLoS One
Title:	Transgenic expression of nonclassically secreted FGF suppresses kidney repair.
Volume:	7
Issue:	5
Pages:	e36485

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Publication

19188682 | J:171262

First Author:	Qatanani M
Year:	2009
Journal:	J Clin Invest
Title:	Macrophage-derived human resistin exacerbates adipose tissue inflammation and insulin resistance in mice.
Volume:	119
Issue:	3
Pages:	531-9

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Publication

21670279 | J:173549

First Author:	Lutz J
Year:	2011
Journal:	Proc Natl Acad Sci U S A
Title:	Pro-B cells sense productive immunoglobulin heavy chain rearrangement irrespective of polypeptide production.
Volume:	108
Issue:	26
Pages:	10644-9

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Publication

19339711 | J:147330

First Author:	Yamaguchi R
Year:	2009
Journal:	Biol Reprod
Title:	Disruption of ADAM3 impairs the migration of sperm into oviduct in mouse.
Volume:	81
Issue:	1
Pages:	142-6

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Publication

26965826 | J:231659

First Author:	Chattopadhyay A
Year:	2016
Journal:	J Lipid Res
Title:	Tg6F ameliorates the increase in oxidized phospholipids in the jejunum of mice fed unsaturated LysoPC or WD.
Volume:	57
Issue:	5
Pages:	832-47

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Publication

23913443 | J:203279

First Author:	Prevost G
Year:	2013
Journal:	Endocrinology
Title:	The PACAP-regulated gene selenoprotein T is abundantly expressed in mouse and human β-cells and its targeted inactivation impairs glucose tolerance.
Volume:	154
Issue:	10
Pages:	3796-806

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Protein

H7BX59

Organism:	Mus musculus/domesticus
Length:	441
Fragment?:	false

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Publication

12454277 | J:80688

First Author:	Miyazaki M
Year:	2002
Journal:	J Lipid Res
Title:	Lack of stearoyl-CoA desaturase-1 function induces a palmitoyl-CoA Delta6 desaturase and represses the stearoyl-CoA desaturase-3 gene in the preputial glands of the mouse.
Volume:	43
Issue:	12
Pages:	2146-54

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Publication

18723443 | J:152636

First Author:	Salikhova A
Year:	2008
Journal:	Circ Res
Title:	Vascular endothelial growth factor and semaphorin induce neuropilin-1 endocytosis via separate pathways.
Volume:	103
Issue:	6
Pages:	e71-9

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Publication

24990931 | J:212535

First Author:	Somasundaram A
Year:	2014
Journal:	J Neurosci
Title:	Store-operated CRAC channels regulate gene expression and proliferation in neural progenitor cells.
Volume:	34
Issue:	27
Pages:	9107-23

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Publication

25733887 | J:220310

First Author:	Held K
Year:	2015
Journal:	Proc Natl Acad Sci U S A
Title:	Activation of TRPM3 by a potent synthetic ligand reveals a role in peptide release.
Volume:	112
Issue:	11
Pages:	E1363-72

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Publication

23085146 | J:211914

First Author:	Quintana A
Year:	2013
Journal:	Brain Behav Immun
Title:	Astrocyte-specific deficiency of interleukin-6 and its receptor reveal specific roles in survival, body weight and behavior.
Volume:	27
Issue:	1
Pages:	162-73

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Publication

15464755 | J:92979

First Author:	Hygge-Blakeman K
Year:	2004
Journal:	Brain Res
Title:	Galanin over-expression decreases the development of neuropathic pain-like behaviors in mice after partial sciatic nerve injury.
Volume:	1025
Issue:	1-2
Pages:	152-8

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Publication

15885921 | J:104267

First Author:	He B
Year:	2005
Journal:	Neuroscience
Title:	Ectopic galanin expression and normal galanin receptor 2 and galanin receptor 3 mRNA levels in the forebrain of galanin transgenic mice.
Volume:	133
Issue:	2
Pages:	371-80

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Publication

20004335 | J:157471

First Author:	Karatayev O
Year:	2009
Journal:	Alcohol
Title:	Increased intake of ethanol and dietary fat in galanin overexpressing mice.
Volume:	43
Issue:	8
Pages:	571-80

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Publication

15380926 | J:132463

First Author:	Laplante F
Year:	2004
Journal:	Regul Pept
Title:	Selective reduction in ventral hippocampal acetylcholine release in awake galanin-treated rats and galanin-overexpressing transgenic mice.
Volume:	122
Issue:	2
Pages:	91-8

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Publication

35361814 | J:323357

First Author:	Curdt N
Year:	2022
Journal:	Sci Rep
Title:	Search strategy analysis of Tg4-42 Alzheimer Mice in the Morris Water Maze reveals early spatial navigation deficits.
Volume:	12
Issue:	1
Pages:	5451

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Publication

30670962 | J:276311

First Author:	Bouter C
Year:	2018
Journal:	Front Aging Neurosci
Title:	¹⁸F-FDG-PET Detects Drastic Changes in Brain Metabolism in the Tg4-42 Model of Alzheimer's Disease.
Volume:	10

Pages:	425

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Publication

21061049 | J:297621

First Author:	Bohórquez DV
Year:	2011
Journal:	J Mol Histol
Title:	Characterization of basal pseudopod-like processes in ileal and colonic PYY cells.
Volume:	42
Issue:	1
Pages:	3-13

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Publication

24043261 | J:297622

First Author:	La Sala MS
Year:	2013
Journal:	FASEB J
Title:	Modulation of taste responsiveness by the satiation hormone peptide YY.
Volume:	27
Issue:	12
Pages:	5022-33

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Publication

16626795 | J:128407

First Author:	Wrenn CC
Year:	2006
Journal:	Pharmacol Biochem Behav
Title:	Performance of galanin transgenic mice in the 5-choice serial reaction time attentional task.
Volume:	83
Issue:	3
Pages:	428-40

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Publication

19151091 | -

First Author:	Noma A
Year:	2009
Journal:	Nucleic Acids Res
Title:	Mechanistic characterization of the sulfur-relay system for eukaryotic 2-thiouridine biogenesis at tRNA wobble positions.
Volume:	37
Issue:	4
Pages:	1335-52

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Publication

11673418 | -

First Author:	Rahman A
Year:	2001
Journal:	J Bacteriol
Title:	Identification of the structural gene for the TDP-Fuc4NAc:lipid II Fuc4NAc transferase involved in synthesis of enterobacterial common antigen in Escherichia coli K-12.
Volume:	183
Issue:	22
Pages:	6509-16

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Publication

17216455 | -

First Author:	Chernyshev A
Year:	2007
Journal:	Appl Microbiol Biotechnol
Title:	Thymidyl biosynthesis enzymes as antibiotic targets.
Volume:	74
Issue:	2
Pages:	282-9

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Publication

6090402 | -

First Author:	Nakata A
Year:	1984
Journal:	J Bacteriol
Title:	Regulation of the phosphate regulon in Escherichia coli K-12: regulation of the negative regulatory gene phoU and identification of the gene product.
Volume:	159
Issue:	3
Pages:	979-85

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Publication

26124703 | -

First Author:	Abbasi A
Year:	2015
Journal:	Front Mol Neurosci
Title:	The role of the ubiquitin-editing enzyme A20 in diseases of the central nervous system and other pathological processes.
Volume:	8

Pages:	21

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Publication

16944204 | -

First Author:	Faik A
Year:	2006
Journal:	Mol Genet Genomics
Title:	Putative fasciclin-like arabinogalactan-proteins (FLA) in wheat (Triticum aestivum) and rice (Oryza sativa): identification and bioinformatic analyses.
Volume:	276
Issue:	5
Pages:	478-94

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Publication

6317672 | -

First Author:	Guranowski A
Year:	1983
Journal:	J Biol Chem
Title:	Catabolism of diadenosine 5',5"'-P1,P4-tetraphosphate in procaryotes. Purification and properties of diadenosine 5',5"'-P1,P4-tetraphosphate (symmetrical) pyrophosphohydrolase from Escherichia coli K12.
Volume:	258
Issue:	24
Pages:	14784-9

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Publication

16449659 | -

First Author:	Nourani A
Year:	2006
Journal:	Mol Cell Biol
Title:	Evidence that Spt2/Sin1, an HMG-like factor, plays roles in transcription elongation, chromatin structure, and genome stability in Saccharomyces cerevisiae.
Volume:	26
Issue:	4
Pages:	1496-509

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Publication

26872373 | -

First Author:	Belkhiri A
Year:	2016
Journal:	Oncotarget
Title:	DARPP-32: from neurotransmission to cancer.
Volume:	7
Issue:	14
Pages:	17631-40

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Publication

11809724 | -

First Author:	Errico A
Year:	2002
Journal:	Hum Mol Genet
Title:	Spastin, the protein mutated in autosomal dominant hereditary spastic paraplegia, is involved in microtubule dynamics.
Volume:	11
Issue:	2
Pages:	153-63

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Publication

10364251 | -

First Author:	Kikuchi A
Year:	1999
Journal:	J Biol Chem
Title:	Evidence for covalent attachment of diphytanylglyceryl phosphate to the cell-surface glycoprotein of Halobacterium halobium.
Volume:	274
Issue:	25
Pages:	18011-6

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Publication

12704671 | -

First Author:	Loriot A
Year:	2003
Journal:	Int J Cancer
Title:	Five new human cancer-germline genes identified among 12 genes expressed in spermatogonia.
Volume:	105
Issue:	3
Pages:	371-6

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Publication

18345015 | -

First Author:	Eulalio A
Year:	2008
Journal:	Nat Struct Mol Biol
Title:	GW182 interaction with Argonaute is essential for miRNA-mediated translational repression and mRNA decay.
Volume:	15
Issue:	4
Pages:	346-53

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Publication

10978529 | -

First Author:	Perez A
Year:	2000
Journal:	Biochim Biophys Acta
Title:	Characterization of the 5'-flanking region of the gene encoding the 50 kDa subunit of human DNA polymerase delta.
Volume:	1493
Issue:	1-2
Pages:	231-6

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Protein Coding Gene

MGI:2447773 | Fam83a

Type:	protein_coding_gene
Organism:	mouse, laboratory

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Publication

17098861 | J:117159

First Author:	Louet JF
Year:	2006
Journal:	Proc Natl Acad Sci U S A
Title:	Oncogenic steroid receptor coactivator-3 is a key regulator of the white adipogenic program.
Volume:	103
Issue:	47
Pages:	17868-73

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Publication

35269658 | J:329149

First Author:	Vecellio Reane D
Year:	2022
Journal:	Int J Mol Sci
Title:	The Splicing of the Mitochondrial Calcium Uniporter Genuine Activator MICU1 Is Driven by RBFOX2 Splicing Factor during Myogenic Differentiation.
Volume:	23
Issue:	5

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Publication

8871632 | J:36662

First Author:	Ridderstad A
Year:	1996
Journal:	J Immunol
Title:	The xid mutation diminishes memory B cell generation but does not affect somatic hypermutation and selection.
Volume:	157
Issue:	8
Pages:	3357-65

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Publication

39580603 | J:359463

First Author:	Mañas-Ojeda A
Year:	2024
Journal:	Mol Psychiatry
Title:	Activation of somatostatin neurons in the medial amygdala reverses long-term aggression and social deficits associated to early-life stress in male mice.

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Publication

9223328 | J:41950

First Author:	Liu Y
Year:	1997
Journal:	Proc Natl Acad Sci U S A
Title:	Mouse model of GM2 activator deficiency manifests cerebellar pathology and motor impairment.
Volume:	94
Issue:	15
Pages:	8138-43

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Publication

9753324 | J:49850

First Author:	Butz S
Year:	1998
Journal:	Cell
Title:	A tripartite protein complex with the potential to couple synaptic vesicle exocytosis to cell adhesion in brain.
Volume:	94
Issue:	6
Pages:	773-82

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Publication

34822722 | J:319392

First Author:	Taiyab A
Year:	2022
Journal:	J Neurosci Res
Title:	Deletion of transcription factor AP-2β from the developing murine trabecular meshwork region leads to progressive glaucomatous changes.
Volume:	100
Issue:	2
Pages:	638-652

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Publication

22067542 | J:184588

First Author:	Nguyen MA
Year:	2011
Journal:	Brain
Title:	Hypertrophy and dietary tyrosine ameliorate the phenotypes of a mouse model of severe nemaline myopathy.
Volume:	134
Issue:	Pt 12
Pages:	3516-29

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Publication

9722161 | J:49333

First Author:	Wutz A
Year:	1998
Journal:	Mol Cell Endocrinol
Title:	Imprinting of the mouse Igf2r gene depends on an intronic CpG island.
Volume:	140
Issue:	1-2
Pages:	9-14

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Protein

F6VQN0

Organism:	Mus musculus/domesticus
Length:	277
Fragment?:	true

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Protein

Q8BQP2

Organism:	Mus musculus/domesticus
Length:	207
Fragment?:	false

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Protein Domain

IPR000834 | Peptidase_M14

Type:

Domain

Description:

Over 70 metallopeptidase families have been identified to date. In these enzymes a divalent cation which is usually zinc, but may be cobalt, manganese or copper, activates the water molecule. The metal ion is held in place by amino acid ligands, usually three in number. In some families of co-catalytic metallopeptidases, two metal ions are observed in crystal structures ligated by five amino acids, with one amino acid ligating both metal ions. The known metal ligands are His, Glu, Asp or Lys. At least one other residue is required for catalysis, which may play an electrophillic role. Many metalloproteases contain an HEXXH motif, which has been shown in crystallographic studies to form part of the metal-binding site []. The HEXXH motif is relatively common, but can be more stringently defined for metalloproteases as 'abXHEbbHbc', where 'a' is most often valine or threonine and forms part of the S1' subsite in thermolysin and neprilysin, 'b' is an uncharged residue, and 'c' a hydrophobic residue. Proline is never found in this site, possibly because it would break the helical structure adopted by this motif in metalloproteases [].This group of sequences contain a diverse range of gene families, which include metallopeptidases belonging to MEROPS peptidase family M14 (carboxypeptidase A, clan MC), subfamilies M14A and M14B.The carboxypeptidase A family can be divided into four subfamilies: M14A(carboxypeptidase A or digestive), M14B (carboxypeptidase H or regulatory), M14C (gamma-D-glutamyl-L-diamino acid peptidase I) and M14D (AGTPBP-1/Nna1-like proteins) [, ]. Members of subfamily M14B have longer C-termini than those of subfamily M14A [], and carboxypeptidase M (a member of the H family) is bound to the membrane by a glycosylphosphatidylinositol anchor, unlike the majority of the M14 family, which are soluble [].ATP/GTP binding protein (AGTPBP-1/Nna1)-like proteins are active metallopeptidases that act on cytosolic proteins such as alpha-tubulin, to remove a C-terminal tyrosine. Mutations in AGTPBP-1/Nna1 cause Purkinje cell degeneration (pcd). AGTPBP-1/Nna1-like proteins from the different phyla are highly diverse, but they all contain a unique N-terminal conserved domain right before the CP domain. It has been suggested that this N-terminal domain might act as a folding domain [, , , ].The zinc ligands have been determined as two histidines and a glutamate,and the catalytic residue has been identified as a C-terminal glutamate,but these do not form the characteristic metalloprotease HEXXH motif [, ]. Members of the carboxypeptidase A family are synthesised as inactive molecules with propeptides that must be cleaved to activate the enzyme. Structural studies of carboxypeptidases A and B reveal the propeptide to exist as a globular domain, followed by an extended α-helix; this shields the catalytic site, without specifically binding to it, while the substrate-binding site is blocked by making specific contacts [, ].

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Publication

29771332 | J:264569

First Author:	Morriss GR
Year:	2018
Journal:	Hum Mol Genet
Title:	Mechanisms of skeletal muscle wasting in a mouse model for myotonic dystrophy type 1.
Volume:	27
Issue:	16
Pages:	2789-2804

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Publication

10430930 | J:56614

First Author:	Gabriel JM
Year:	1999
Journal:	Proc Natl Acad Sci U S A
Title:	A transgene insertion creating a heritable chromosome deletion mouse model of Prader-Willi and angelman syndromes.
Volume:	96
Issue:	16
Pages:	9258-63

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Protein Coding Gene

MGI:98497 | Tbxas1

Type:	protein_coding_gene
Organism:	mouse, laboratory

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Publication

27111234 | J:237079

First Author:	Kupz A
Year:	2016
Journal:	J Clin Invest
Title:	ESAT-6-dependent cytosolic pattern recognition drives noncognate tuberculosis control in vivo.
Volume:	126
Issue:	6
Pages:	2109-22

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Publication

30625321 | J:279532

First Author:	Ribic A
Year:	2019
Journal:	Cell Rep
Title:	Synapse-Selective Control of Cortical Maturation and Plasticity by Parvalbumin-Autonomous Action of SynCAM 1.
Volume:	26
Issue:	2
Pages:	381-393.e6

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Publication

32251313 | J:299386

First Author:	Hagiwara A
Year:	2020
Journal:	Sci Rep
Title:	Impaired experience-dependent maternal care in presynaptic active zone protein CAST-deficient dams.
Volume:	10
Issue:	1
Pages:	5238

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Publication

1314164 | -

First Author:	Kashishian A
Year:	1992
Journal:	EMBO J
Title:	Phosphorylation sites in the PDGF receptor with different specificities for binding GAP and PI3 kinase in vivo.
Volume:	11
Issue:	4
Pages:	1373-82

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Publication

21639793 | -

First Author:	Battesti A
Year:	2011
Journal:	Annu Rev Microbiol
Title:	The RpoS-mediated general stress response in Escherichia coli.
Volume:	65

Pages:	189-213

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Publication

10066472 | -

First Author:	Ishihama A
Year:	1998
Journal:	Curr Opin Microbiol
Title:	Subunits of yeast RNA polymerases: structure and function.
Volume:	1
Issue:	2
Pages:	190-6

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Publication

1653029 | -

First Author:	Kazlauskas A
Year:	1991
Journal:	Cell Regul
Title:	Functions of the major tyrosine phosphorylation site of the PDGF receptor beta subunit.
Volume:	2
Issue:	6
Pages:	413-25

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Publication

37223028 | J:337239

First Author:	Ruiz-Otero N
Year:	2023
Journal:	Front Endocrinol (Lausanne)
Title:	Role of Delta/Notch-like EGF-related receptor in blood glucose homeostasis.
Volume:	14

Pages:	1161085

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Protein

D3YWU8

Organism:	Mus musculus/domesticus
Length:	147
Fragment?:	true

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Protein

D3Z092

Organism:	Mus musculus/domesticus
Length:	162
Fragment?:	true

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Publication

19299736 | J:147194

First Author:	Livraghi A
Year:	2009
Journal:	J Immunol
Title:	Airway and lung pathology due to mucosal surface dehydration in {beta}-epithelial Na+ channel-overexpressing mice: role of TNF-{alpha} and IL-4R{alpha} signaling, influence of neonatal development, and limited efficacy of glucocorticoid treatment.
Volume:	182
Issue:	7
Pages:	4357-67

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Publication

19531263 | -

First Author:	Köhrmann A
Year:	2009
Journal:	BMC Cancer
Title:	Expression of matrix metalloproteinases (MMPs) in primary human breast cancer and breast cancer cell lines: New findings and review of the literature.
Volume:	9

Pages:	188

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Publication

15019987 | -

First Author:	Blomstergren A
Year:	2004
Journal:	Gene
Title:	Comparative analysis of the complete cag pathogenicity island sequence in four Helicobacter pylori isolates.
Volume:	328

Pages:	85-93

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Publication

32127496 | J:308849

First Author:	Kharbanda A
Year:	2020
Journal:	Sci Signal
Title:	Blocking EGFR palmitoylation suppresses PI3K signaling and mutant KRAS lung tumorigenesis.
Volume:	13
Issue:	621

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Publication

9510032 | J:46130

First Author:	Nakayama A
Year:	1998
Journal:	Mech Dev
Title:	Mutations in microphthalmia, the mouse homolog of the human deafness gene MITF, affect neuroepithelial and neural crest-derived melanocytes differently.
Volume:	70
Issue:	1-2
Pages:	155-66

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Publication

33529159 | J:307028

First Author:	Li J
Year:	2021
Journal:	J Clin Invest
Title:	TorsinA restoration in a mouse model identifies a critical therapeutic window for DYT1 dystonia.
Volume:	131
Issue:	6

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Publication

23292934 | J:193718

First Author:	Kandyba E
Year:	2013
Journal:	Proc Natl Acad Sci U S A
Title:	Competitive balance of intrabulge BMP/Wnt signaling reveals a robust gene network ruling stem cell homeostasis and cyclic activation.
Volume:	110
Issue:	4
Pages:	1351-6

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Publication

9478921 | J:46266

First Author:	Di Cristofano A
Year:	1998
Journal:	J Biol Chem
Title:	Molecular cloning and characterization of p56dok-2 defines a new family of RasGAP-binding proteins.
Volume:	273
Issue:	9
Pages:	4827-30

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Publication

26061883 | J:233811

First Author:	Gosain A
Year:	2015
Journal:	PLoS One
Title:	Impaired Cellular Immunity in the Murine Neural Crest Conditional Deletion of Endothelin Receptor-B Model of Hirschsprung's Disease.
Volume:	10
Issue:	6
Pages:	e0128822

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Publication

11509733 | J:70892

First Author:	Ylikorkala A
Year:	2001
Journal:	Science
Title:	Vascular abnormalities and deregulation of VEGF in Lkb1-deficient mice.
Volume:	293
Issue:	5533
Pages:	1323-6

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Publication

32116022 | J:300037

First Author:	Orekhova A
Year:	2020
Journal:	Am J Physiol Gastrointest Liver Physiol
Title:	Ethanol feeding accelerates pancreatitis progression in CPA1 N256K mutant mice.
Volume:	318
Issue:	4
Pages:	G694-G704

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Publication

15972954 | J:99511

First Author:	Agah A
Year:	2005
Journal:	Am J Pathol
Title:	Proteolysis of cell-surface tissue transglutaminase by matrix metalloproteinase-2 contributes to the adhesive defect and matrix abnormalities in thrombospondin-2-null fibroblasts and mice.
Volume:	167
Issue:	1
Pages:	81-8

•

Protein

F6VA34

Organism:	Mus musculus/domesticus
Length:	122
Fragment?:	true

•

Protein

Q3V0E2

Organism:	Mus musculus/domesticus
Length:	128
Fragment?:	false

•

Protein

A2ARC0

Organism:	Mus musculus/domesticus
Length:	163
Fragment?:	false

•

Publication

15886391 | -

First Author:	Galhardo RS
Year:	2005
Journal:	Nucleic Acids Res
Title:	An SOS-regulated operon involved in damage-inducible mutagenesis in Caulobacter crescentus.
Volume:	33
Issue:	8
Pages:	2603-14

•

Protein Domain

IPR024858 | Golgin_A

Type:

Family

Description:

Members of the golgin subfamily A were identified as Golgi auto-antigens []. They might be involved in maintaining cis-Golgi structure []. One of the members of this family, member 2 or GM130, is a specific interacting partner of the small GTPase Rab1b []and plays a key role in the disassembly and reassembly of the Golgi apparatus during mitosis. GM130 is also involved in vesicle tethering and fusion at the cis-cisternae to facilitate transit between transport vesicles and the stacked cisternae. It interacts with GRASPs proteins, which mediate the stacking of Golgi cisternae []. Additionally, GM130 was localised to the spindle poles and regulates microtubule organization [].Structurally, GM130 is comprised of six coiled-coil regions in the middle, a Golgi-targeting domain at the C terminus, and a p115-interacting motif at the N terminus [].

•

Protein Domain

IPR017026 | ImuA

Type:

Family

Description:

This entry represents inducible mutagenesis protein A (ImuA), believed to be involved in DNA damage tolerance in a number of bacteria. This protein is often encoded in a operon with DnaE2 (a second copy of the catalytic subunit of DNA polymerase III), and ImuB (whose function is not known though it is similar to the Y-family of DNA polymerases), though the genes may also be encoded in separate regions. In Caulobacter crescentus (Caulobacter vibrioides) the imuAB/dnaE2 operon is induced by DNA damage in a RecA-dependent manner and is required for the error-prone processing of DNA lesions []. Strains deficient in these genes showed extreme sensitivity to mutagenic agents such as UV or the drug mitC. The function of ImuA is not known but sequence analysis suggests that it contains a P-loop nucleoside triphosphate hydrolase domain.

•

Protein Domain

IPR001038 | GA_GC

Type:

Family

Description:

Equid herpesvirus 1 (Equine herpesvirus 1, EHV-1) glycoprotein 13 (EHV-1 gp13) has the characteristic features of a membrane-spanning protein: an N-terminal signal sequence; a hydrophobic membrane anchor region; a charged C-terminal cytoplasmic tail; and an exterior domain with nine potential N-glycosylation sites []. EHV-1 gp13 is the structural homologue of the gC-like glycoproteins of the Human herpesvirus 1 (HHV-1) and Human herpesvirus 2 (HHV-2) (gC-1 and gC-2 respectively), Pseudorabies virus (strain Indiana-Funkhauser/Becker) (PRV) (gIII) and Human herpesvirus 3 (HHV-3) (gp66). Secretory glycoprotein GP57-65 precursor (glycoprotein A - GA) is similar to Herpesvirus glycoprotein C, and belongs to the immunoglobulin gene superfamily [, ]. GA is thought to play an immunoevasive role in the pathogenesis of Marek's disease. It is a candidate for causing the early-stage immunosuppression that occurs after MDHV infection.

•

Publication

18541670 | J:137926

First Author:	Bouska A
Year:	2008
Journal:	Mol Cell Biol
Title:	Mdm2 promotes genetic instability and transformation independent of p53.
Volume:	28
Issue:	15
Pages:	4862-74

•

Publication

20452353 | J:337198

First Author:	Morton JP
Year:	2010
Journal:	Gastroenterology
Title:	LKB1 haploinsufficiency cooperates with Kras to promote pancreatic cancer through suppression of p21-dependent growth arrest.
Volume:	139
Issue:	2
Pages:	586-97, 597.e1-6

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Publication

11693491 | J:153346

First Author:	Lin TM
Year:	2001
Journal:	J Toxicol Environ Health A
Title:	Role of the aryl hydrocarbon receptor in the development of control and 2,3,7,8-tetrachlorodibenzo-p-dioxin-exposed male mice.
Volume:	64
Issue:	4
Pages:	327-42

•

Publication

21807912 | J:176002

First Author:	Werner JL
Year:	2011
Journal:	Infect Immun
Title:	Neutrophils produce interleukin 17A (IL-17A) in a dectin-1- and IL-23-dependent manner during invasive fungal infection.
Volume:	79
Issue:	10
Pages:	3966-77

•

Publication

12702868 | J:83880

First Author:	Eden A
Year:	2003
Journal:	Science
Title:	Chromosomal instability and tumors promoted by DNA hypomethylation.
Volume:	300
Issue:	5618
Pages:	455

•

Publication

22727490 | J:187413

First Author:	Müller AJ
Year:	2012
Journal:	Immunity
Title:	CD4+ T cells rely on a cytokine gradient to control intracellular pathogens beyond sites of antigen presentation.
Volume:	37
Issue:	1
Pages:	147-57

•

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