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Search results 17801 to 17900 out of 2418182 for a

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Type Details Score
Publication
28003225 | J:328173
First Author: Amirouche A
Year: 2017
Journal: Am J Physiol Cell Physiol
Title: Muscle-specific microRNA-206 targets multiple components in dystrophic skeletal muscle representing beneficial adaptations.
Volume: 312
Issue: 3
Pages: C209-C221
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Publication
27311019 | J:249214
First Author: Kassem A
Year: 2016
Journal: PLoS One
Title: Toll-Like Receptor 2 Stimulation of Osteoblasts Mediates Staphylococcus Aureus Induced Bone Resorption and Osteoclastogenesis through Enhanced RANKL.
Volume: 11
Issue: 6
Pages: e0156708
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Publication
38668123 | J:361497
First Author: Palumbo F
Year: 2024
Journal: Cytometry A
Title: Impact of different tissue dissociation protocols on endothelial cell recovery from developing mouse lungs.
Volume: 105
Issue: 7
Pages: 521-535
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Publication
37770940 | J:341360
First Author: Alvarez-Artime A
Year: 2023
Journal: Cell Commun Signal
Title: Castration promotes the browning of the prostate tumor microenvironment.
Volume: 21
Issue: 1
Pages: 267
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Publication
16818796 | J:135036
First Author: Lartigue A
Year: 2006
Journal: J Immunol
Title: Role of TLR9 in anti-nucleosome and anti-DNA antibody production in lpr mutation-induced murine lupus.
Volume: 177
Issue: 2
Pages: 1349-54
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Protein
Q3TMH2
Organism: Mus musculus/domesticus
Length: 418  
Fragment?: false
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Protein
Q8VCA8
Organism: Mus musculus/domesticus
Length: 425  
Fragment?: false
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Protein
Q9CZC8
Organism: Mus musculus/domesticus
Length: 414  
Fragment?: false
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Protein
Q91XF1
Organism: Mus musculus/domesticus
Length: 277  
Fragment?: true
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Protein
A2A709
Organism: Mus musculus/domesticus
Length: 181  
Fragment?: true
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Protein
D3YXW0
Organism: Mus musculus/domesticus
Length: 76  
Fragment?: true
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Protein
Q6P6J8
Organism: Mus musculus/domesticus
Length: 188  
Fragment?: true
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Protein
A0A0N4SWD0
Organism: Mus musculus/domesticus
Length: 164  
Fragment?: true
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Protein
A2AWQ9
Organism: Mus musculus/domesticus
Length: 189  
Fragment?: false
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Protein
A0A0N4SVR0
Organism: Mus musculus/domesticus
Length: 52  
Fragment?: true
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Publication
12717035 | -
First Author: Pei J
Year: 2003
Journal: Protein Sci
Title: Peptidase family U34 belongs to the superfamily of N-terminal nucleophile hydrolases.
Volume: 12
Issue: 5
Pages: 1131-5
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Protein Domain
IPR005322 | Peptidase_C69
Type: Family
Description: This group of peptidases, belong to MEROPS peptidase family C69 (dipeptidase, clan PB). They are mainly dipeptidases []and incude dipeptidase A from Lactobacillus helveticus (MEROPS identifier C69.001). Comparative sequence and structural analysis, particularly to penicillin V acylase (MEROPS peptidase family C59) revealed a cysteine as the catalytic nucleophile as well as other conserved residues important for catalysis []. In general, C69 family is variable in sequence and exhibits great diversity in substrate specificity, to include enzymes such as choloyglycine hydrolases, acid ceramidases, isopenicillin N acyltransferases, and a subgroup of eukaryotic proteins with unclear function.A cysteine peptidase is a proteolytic enzyme that hydrolyses a peptide bond using the thiol group of a cysteine residue as a nucleophile. Hydrolysis involves usually a catalytic triad consisting of the thiol group of the cysteine, the imidazolium ring of a histidine, and a third residue, usually asparagine or aspartic acid, to orientate and activate the imidazolium ring. In only one family of cysteine peptidases, is the role of the general base assigned to a residue other than a histidine: in peptidases from family C89 (acid ceramidase) an arginine is the general base. Cysteine peptidases can be grouped into fourteen different clans, with members of each clan possessing a tertiary fold unique to the clan. Four clans of cysteine peptidases share structural similarities with serine and threonine peptidases and asparagine lyases. From sequence similarities, cysteine peptidases can be clustered into over 80 different families []. Clans CF, CM, CN, CO, CP and PD contain only one family.Cysteine peptidases are often active at acidic pH and are therefore confined to acidic environments, such as the animal lysosome or plant vacuole. Cysteine peptidases can be endopeptidases, aminopeptidases, carboxypeptidases, dipeptidyl-peptidases or omega-peptidases. They are inhibited by thiol chelators such as iodoacetate, iodoacetic acid, N-ethylmaleimide or p-chloromercuribenzoate.Clan CA includes proteins with a papain-like fold. There is a catalytic triad which occurs in the order: Cys/His/Asn (or Asp). A fourth residue, usually Gln, is important for stabilising the acyl intermediate that forms during catalysis, and this precedes the active site Cys. The fold consistsof two subdomains with the active site between them. One subdomain consists of a bundle of helices, with the catalytic Cys at the end of one of them, and the other subdomain is a β-barrel with the active site His and Asn (or Asp). There are over thirty families in the clan, and tertiary structures have been solved for members of most of these. Peptidases in clan CA are usually sensitive to the small molecule inhibitor E64, which is ineffective against peptidases from other clans of cysteine peptidases [].Clan CD includes proteins with a caspase-like fold. Proteins in the clan have an α/β/α sandwich structure. There is a catalytic dyad which occurs in the order His/Cys. The active site His occurs in a His-Gly motif and the active site Cys occurs in an Ala-Cys motif; both motifs are preceded by a block of hydrophobic residues []. Specificity is predominantly directed towards residues that occupy the S1 binding pocket, so that caspases cleave aspartyl bonds, legumains cleave asparaginyl bonds, and gingipains cleave lysyl or arginyl bonds.Clan CE includes proteins with an adenain-like fold. The fold consists of two subdomains with the active site between them. One domain is a bundle of helices, and the other a β-barrell. The subdomains are in the opposite order to those found in peptidases from clan CA, and this is reflected in the order of active site residues: His/Asn/Gln/Cys. This has prompted speculation that proteins in clans CA and CE are related, and that members of one clan are derived from a circular permutation of the structure of the other.Clan CL includes proteins with a sortase B-like fold. Peptidases in the clan hydrolyse and transfer bacterial cell wall peptides. The fold shows a closed β-barrel decorated with helices with the active site at one end of the barrel []. The active site consists of a His/Cys catalytic dyad.Cysteine peptidases with a chymotrypsin-like fold are included in clan PA, which also includes serine peptidases. Cysteine peptidases that are N-terminal nucleophile hydrolases are included in clan PB. Cysteine peptidases with a tertiary structure similar to that of the serine-type aspartyl dipeptidase are included in clan PC. Cysteine peptidases with an intein-like fold are included in clan PD, which also includes asparagine lyases.
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Publication
37996657 | J:352508
First Author: Nsiah NY
Year: 2023
Journal: Sci Rep
Title: Long-term HIF-1α stabilization reduces respiration, promotes mitophagy, and results in retinal cell death.
Volume: 13
Issue: 1
Pages: 20541
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Publication
30254177 | J:266567
First Author: Honda T
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: A single phosphorylation site of SIK3 regulates daily sleep amounts and sleep need in mice.
Volume: 115
Issue: 41
Pages: 10458-10463
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Publication
20862307 | J:165664
First Author: Chun MG
Year: 2010
Journal: PLoS Genet
Title: Genetic deletion of the desmosomal component desmoplakin promotes tumor microinvasion in a mouse model of pancreatic neuroendocrine carcinogenesis.
Volume: 6
Issue: 9
Pages: e1001120
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Publication
17724450 | J:130249
First Author: Meissner A
Year: 2007
Journal: Nat Biotechnol
Title: Direct reprogramming of genetically unmodified fibroblasts into pluripotent stem cells.
Volume: 25
Issue: 10
Pages: 1177-81
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Publication
18391523 | J:137277
First Author: Ross A
Year: 2007
Journal: Sex Dev
Title: Bmp7 regulates germ cell proliferation in mouse fetal gonads.
Volume: 1
Issue: 2
Pages: 127-37
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Allele
jb | MGI:1856613
 
Name: juvenile bare
Allele Type: Spontaneous
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Protein Coding Gene
MGI:1351668 | Abca8b
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
29470501 | J:258742
First Author: Freschi A
Year: 2018
Journal: PLoS Genet
Title: Tissue-specific and mosaic imprinting defects underlie opposite congenital growth disorders in mice.
Volume: 14
Issue: 2
Pages: e1007243
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Publication
20837772 | J:165264
First Author: Bozec A
Year: 2010
Journal: J Cell Biol
Title: Fra-2/AP-1 controls bone formation by regulating osteoblast differentiation and collagen production.
Volume: 190
Issue: 6
Pages: 1093-106
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Protein
Q91ZX1
Organism: Mus musculus/domesticus
Length: 238  
Fragment?: false
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Protein
A0A140LI09
Organism: Mus musculus/domesticus
Length: 179  
Fragment?: false
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GO Term
GO:0015395 | nucleoside transmembrane transporter activity, down a concentration gradient
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Publication
39351282 | J:354851
 
First Author: Olczak A
Year: 2024
Journal: Front Physiol
Title: The overexpression of R-spondin 3 affects hair morphogenesis and hair development along with the formation and maturation of the hair follicle stem cells.
Volume: 15
Pages: 1424077
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Publication
36817480 | J:343342
 
First Author: Ménoret A
Year: 2023
Journal: Front Immunol
Title: Antigen-specific downregulation of miR-150 in CD4 T cells promotes cell survival.
Volume: 14
Pages: 1102403
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Publication
17606634 | J:125878
First Author: Schaefer A
Year: 2007
Journal: J Exp Med
Title: Cerebellar neurodegeneration in the absence of microRNAs.
Volume: 204
Issue: 7
Pages: 1553-8
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Publication
35649348 | J:358557
First Author: Ramos-Prats A
Year: 2022
Journal: Cell Rep
Title: VIP-expressing interneurons in the anterior insular cortex contribute to sensory processing to regulate adaptive behavior.
Volume: 39
Issue: 9
Pages: 110893
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Publication
7511095 | J:18013
First Author: Hahnel A
Year: 1994
Journal: Endocrinology
Title: Insulin-like growth factor binding proteins are transcribed by preimplantation mouse embryos.
Volume: 134
Issue: 4
Pages: 1956-9
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Publication
33406854 | J:321055
First Author: Yurdagul A Jr
Year: 2021
Journal: Arterioscler Thromb Vasc Biol
Title: ODC (Ornithine Decarboxylase)-Dependent Putrescine Synthesis Maintains MerTK (MER Tyrosine-Protein Kinase) Expression to Drive Resolution.
Volume: 41
Issue: 3
Pages: e144-e159
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Publication
29031732 | J:262468
First Author: Epshtein A
Year: 2017
Journal: Mol Metab
Title: Neonatal pancreatic pericytes support β-cell proliferation.
Volume: 6
Issue: 10
Pages: 1330-1338
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Publication
26420784 | J:226543
First Author: Prönneke A
Year: 2015
Journal: Cereb Cortex
Title: Characterizing VIP Neurons in the Barrel Cortex of VIPcre/tdTomato Mice Reveals Layer-Specific Differences.
Volume: 25
Issue: 12
Pages: 4854-68
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Protein
Q8BIV7
Organism: Mus musculus/domesticus
Length: 751  
Fragment?: false
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Protein
B0QZL3
Organism: Mus musculus/domesticus
Length: 675  
Fragment?: false
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Publication
17213309 | J:119234
First Author: de la Fuente MA
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: WIP is a chaperone for Wiskott-Aldrich syndrome protein (WASP).
Volume: 104
Issue: 3
Pages: 926-31
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Publication
33664861 | J:316702
First Author: Garzón-Tituaña M
Year: 2021
Journal: Theranostics
Title: Granzyme A inhibition reduces inflammation and increases survival during abdominal sepsis.
Volume: 11
Issue: 8
Pages: 3781-3795
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Publication
33013313 | J:311290
 
First Author: Bouter Y
Year: 2020
Journal: Front Neurosci
Title: miRNA Alterations Elicit Pathways Involved in Memory Decline and Synaptic Function in the Hippocampus of Aged Tg4-42 Mice.
Volume: 14
Pages: 580524
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Publication
21573029 | J:172432
First Author: Flowers MT
Year: 2011
Journal: PLoS One
Title: Metabolic changes in skin caused by Scd1 deficiency: a focus on retinol metabolism.
Volume: 6
Issue: 5
Pages: e19734
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Publication
28346410 | J:260129
First Author: Iwata A
Year: 2017
Journal: Nat Immunol
Title: Quality of TCR signaling determined by differential affinities of enhancers for the composite BATF-IRF4 transcription factor complex.
Volume: 18
Issue: 5
Pages: 563-572
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Publication
8584226 | J:32174
First Author: Migheli A
Year: 1995
Journal: Neurosci Lett
Title: Detection of apoptosis in weaver cerebellum by electron microscopic in situ end-labeling of fragmented DNA.
Volume: 199
Issue: 1
Pages: 53-6
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Publication
11294870 | J:70131
First Author: Khalyfa A
Year: 2001
Journal: J Biol Chem
Title: Characterization of elongation factor-1A (eEF1A-1) and eEF1A-2/S1 protein expression in normal and wasted mice.
Volume: 276
Issue: 25
Pages: 22915-22
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Publication
21490063 | J:171430
First Author: Kobayashi A
Year: 2011
Journal: Development
Title: β-Catenin is essential for Müllerian duct regression during male sexual differentiation.
Volume: 138
Issue: 10
Pages: 1967-75
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Publication
21498588 | J:174701
First Author: Douin-Echinard V
Year: 2011
Journal: J Leukoc Biol
Title: Estradiol administration controls eosinophilia through estrogen receptor-alpha activation during acute peritoneal inflammation.
Volume: 90
Issue: 1
Pages: 145-54
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Publication
21282644 | J:169063
First Author: Green MR
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Signatures of murine B-cell development implicate Yy1 as a regulator of the germinal center-specific program.
Volume: 108
Issue: 7
Pages: 2873-8
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Publication
23798429 | J:198816
First Author: Jain N
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Cell geometric constraints induce modular gene-expression patterns via redistribution of HDAC3 regulated by actomyosin contractility.
Volume: 110
Issue: 28
Pages: 11349-54
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Publication
19340312 | J:148508
First Author: Amleh A
Year: 2009
Journal: PLoS One
Title: Mouse cofactor of BRCA1 (Cobra1) is required for early embryogenesis.
Volume: 4
Issue: 4
Pages: e5034
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Publication
24332837 | J:206836
First Author: Taguchi A
Year: 2014
Journal: Cell Stem Cell
Title: Redefining the in vivo origin of metanephric nephron progenitors enables generation of complex kidney structures from pluripotent stem cells.
Volume: 14
Issue: 1
Pages: 53-67
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Publication
33290502 | J:311217
First Author: Murillo A
Year: 2021
Journal: Cereb Cortex
Title: Temporal Dynamics and Neuronal Specificity of Grin3a Expression in the Mouse Forebrain.
Volume: 31
Issue: 4
Pages: 1914-1926
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Publication
17991882 | J:145593
First Author: Zernecke A
Year: 2008
Journal: Circ Res
Title: Protective role of CXC receptor 4/CXC ligand 12 unveils the importance of neutrophils in atherosclerosis.
Volume: 102
Issue: 2
Pages: 209-17
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Publication
8719347 | J:31081
First Author: Wilson DB
Year: 1995
Journal: J Craniofac Genet Dev Biol
Title: Alterations in cranial morphogenesis in the Lp mutant mouse.
Volume: 15
Issue: 4
Pages: 182-9
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Protein Coding Gene
MGI:894682 | Unc5a
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
26658318 | J:228873
First Author: Stathopoulou A
Year: 2016
Journal: Dev Biol
Title: Inactivation of Geminin in neural crest cells affects the generation and maintenance of enteric progenitor cells, leading to enteric aganglionosis.
Volume: 409
Issue: 2
Pages: 392-405
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Publication
24917500 | J:213874
First Author: Murtomaki A
Year: 2014
Journal: Development
Title: Notch signaling functions in lymphatic valve formation.
Volume: 141
Issue: 12
Pages: 2446-51
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Publication
22658523 | J:187307
First Author: Akhter A
Year: 2012
Journal: Immunity
Title: Caspase-11 promotes the fusion of phagosomes harboring pathogenic bacteria with lysosomes by modulating actin polymerization.
Volume: 37
Issue: 1
Pages: 35-47
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Publication
25961939 | J:231785
First Author: Moriarity BS
Year: 2015
Journal: Nat Genet
Title: A Sleeping Beauty forward genetic screen identifies new genes and pathways driving osteosarcoma development and metastasis.
Volume: 47
Issue: 6
Pages: 615-24
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Publication
1491694 | J:33283
First Author: Law SW
Year: 1992
Journal: Mol Endocrinol
Title: Identification of a new brain-specific transcription factor, NURR1.
Volume: 6
Issue: 12
Pages: 2129-35
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Publication
20421483 | J:160299
First Author: Tsang KM
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Alternate protein kinase A activity identifies a unique population of stromal cells in adult bone.
Volume: 107
Issue: 19
Pages: 8683-8
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Publication
12388783 | J:126302
First Author: Yamaguchi K
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: A GDP/GTP exchange protein for the Rab3 small G protein family up-regulates a postdocking step of synaptic exocytosis in central synapses.
Volume: 99
Issue: 22
Pages: 14536-41
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Publication
1974250 | -
First Author: Ichinose A
Year: 1990
Journal: J Biol Chem
Title: Structure of transglutaminases.
Volume: 265
Issue: 23
Pages: 13411-4
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Publication
27298364 | J:234291
First Author: Wang J
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Activation of the molecular chaperone, sigma 1 receptor, preserves cone function in a murine model of inherited retinal degeneration.
Volume: 113
Issue: 26
Pages: E3764-72
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Publication
22796216 | J:188047
First Author: Kumar A
Year: 2012
Journal: Neurochem Int
Title: Presenilin 1 and 2 are expressed differentially in the cerebral cortex of mice during development.
Volume: 61
Issue: 5
Pages: 778-82
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Publication
7724666 | J:24554
First Author: Duclert A
Year: 1995
Journal: Physiol Rev
Title: Acetylcholine receptor gene expression at the developing neuromuscular junction.
Volume: 75
Issue: 2
Pages: 339-68
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Publication
36196585 | J:331057
 
First Author: Parichha A
Year: 2022
Journal: Development
Title: Dentate gyrus morphogenesis is regulated by β-catenin function in hem-derived fimbrial glia.
Volume: 149
Issue: 21
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Publication
18305161 | J:132859
First Author: Stanic D
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Peptidergic influences on proliferation, migration, and placement of neural progenitors in the adult mouse forebrain.
Volume: 105
Issue: 9
Pages: 3610-5
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Publication
8137236 | J:17125
First Author: von Deimling A
Year: 1994
Journal: Cancer Res
Title: Loci associated with malignant progression in astrocytomas: a candidate on chromosome 19q.
Volume: 54
Issue: 6
Pages: 1397-401
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Protein
A2ASB7
Organism: Mus musculus/domesticus
Length: 151  
Fragment?: true
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Protein
A2ASB1
Organism: Mus musculus/domesticus
Length: 152  
Fragment?: true
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Protein
A2ASB8
Organism: Mus musculus/domesticus
Length: 140  
Fragment?: false
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Protein Coding Gene
MGI:1891250 | Gprc5a
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
27134162 | J:235483
First Author: Haney SL
Year: 2016
Journal: Cell Rep
Title: Promoter Hypomethylation and Expression Is Conserved in Mouse Chronic Lymphocytic Leukemia Induced by Decreased or Inactivated Dnmt3a.
Volume: 15
Issue: 6
Pages: 1190-201
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Publication
16861630 | J:112405
First Author: Mullick A
Year: 2006
Journal: Infect Immun
Title: Cardiac failure in C5-deficient A/J mice after Candida albicans infection.
Volume: 74
Issue: 8
Pages: 4439-51
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Publication
22595668 | J:184750
First Author: Ionescu A
Year: 2012
Journal: Dev Cell
Title: FoxA family members are crucial regulators of the hypertrophic chondrocyte differentiation program.
Volume: 22
Issue: 5
Pages: 927-39
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Publication
25196998 | J:216294
 
First Author: Kumar A
Year: 2014
Journal: Int J Dev Neurosci
Title: Analysis of Presenilin 1 and 2 interacting proteins in mouse cerebral cortex during development.
Volume: 38
Pages: 138-46
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Publication
38652744 | J:357475
First Author: Rojo D
Year: 2024
Journal: Proc Natl Acad Sci U S A
Title: A mammalian tripartite enhancer cluster controls hypothalamic Pomc expression, food intake, and body weight.
Volume: 121
Issue: 18
Pages: e2322692121
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Publication
3858875 | J:30460
First Author: Ghazal P
Year: 1985
Journal: Proc Natl Acad Sci U S A
Title: Evolutionary amplification of a pseudogene.
Volume: 82
Issue: 12
Pages: 4182-5
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Publication
33761356 | J:353222
First Author: Narkar A
Year: 2021
Journal: Cell Rep
Title: On the role of p53 in the cellular response to aneuploidy.
Volume: 34
Issue: 12
Pages: 108892
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Publication
1959134 | J:69572
First Author: Strasser A
Year: 1991
Journal: Cell
Title: bcl-2 transgene inhibits T cell death and perturbs thymic self-censorship.
Volume: 67
Issue: 5
Pages: 889-99
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Publication
34395414 | J:311212
 
First Author: Fantin A
Year: 2021
Journal: Front Cell Dev Biol
Title: KIT Is Required for Fetal Liver Hematopoiesis.
Volume: 9
Pages: 648630
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Publication
27597235 | J:239251
First Author: Brzóska HŁ
Year: 2016
Journal: Kidney Int
Title: Planar cell polarity genes Celsr1 and Vangl2 are necessary for kidney growth, differentiation, and rostrocaudal patterning.
Volume: 90
Issue: 6
Pages: 1274-1284
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Publication
15705720 | J:96834
First Author: Oddo S
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Chronic nicotine administration exacerbates tau pathology in a transgenic model of Alzheimer's disease.
Volume: 102
Issue: 8
Pages: 3046-51
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