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Search results 1801 to 1900 out of 4306 for C3

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0.019s

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Type Details Score
Allele
Cfi<em1Jiwe> | MGI:7507065
Name: complement component factor i; endonuclease-mediated mutation 1, Jiqiu Wen
Allele Type: Endonuclease-mediated
Attribute String: Humanized sequence
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Genotype
Genotype
Symbol: Igkc/Igkc Igl/Igl
Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6 * CBA
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+>
Background: involves: 129
Zygosity: cn
Has Mutant Allele: true
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Publication
17709514 | -
First Author: Rooijakkers SH
Year: 2007
Journal: J Immunol
Title: Staphylococcal complement inhibitor: structure and active sites.
Volume: 179
Issue: 5
Pages: 2989-98
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Publication
16166264 | -
First Author: Lepore BW
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: The x-ray crystal structure of lysine-2,3-aminomutase from Clostridium subterminale.
Volume: 102
Issue: 39
Pages: 13819-24
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Protein Domain
IPR025895 | LAM_C_dom
Type: Domain
Description: This domain is found in the C-terminal of lysine-2,3-aminomutase (LAM) and is involved in dimerisation []. LAM catalyses the interconversion of L-alpha-lysine and L-beta-lysine, which proceeds by migration of the amino group from C2 to C3 concomitant with cross-migration of the 3-pro-R hydrogen of L-alpha-lysine to the 2-pro-R position of L-beta-lysine.
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Protein Domain
IPR021612 | SCIN
Type: Family
Description: SCIN is released by Staphylococcus aureus to counteract the host immune defense. The protein binds to and inhibits C3 convertases on the bacterial surface, reducing phagocytosis and blocking downstream effector functions by C3b deposition on its surface []. An 18 residue stretch 31-48 is crucial for SCIN activity [].
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Publication
21761520 | -
First Author: Guldan H
Year: 2011
Journal: Angew Chem Int Ed Engl
Title: Functional assignment of an enzyme that catalyzes the synthesis of an archaea-type ether lipid in bacteria.
Volume: 50
Issue: 35
Pages: 8188-91
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Publication
23963642 | J:205863
First Author: Cunningham CA
Year: 2013
Journal: Eur J Immunol
Title: The POSH/JIP-1 scaffold network regulates TCR-mediated JNK1 signals and effector function in CD8(+) T cells.
Volume: 43
Issue: 12
Pages: 3361-71
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Publication
8352775 | -
First Author: Nakagawa H
Year: 1993
Journal: Biochem Biophys Res Commun
Title: Complement component C3-derived neutrophil chemotactic factors purified from exudate of rat carrageenin-induced inflammation.
Volume: 194
Issue: 3
Pages: 1181-7
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Publication
17412383 | -
First Author: Rehana S
Year: 2007
Journal: Toxicon
Title: Molecular isoforms of cobra venom factor-like proteins in the venom of Austrelaps superbus.
Volume: 50
Issue: 1
Pages: 32-52
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Protein Domain
IPR035711 | Complement_C3-like
Type: Family
Description: This entry includes complement C3, a major component in the both the classical and alternative complement activation pathways. C3 is cleaved into two chains, known as alpha (C3a) and beta (C3b) by C3 convertases. C3b binds to cell surface carbohydrates or immune aggregates []. C3a is an anaphylatoxin and mediator of a localized inflammatory response, acting as a chemoattractant for neutrophils []. Both alpha and beta chains can be further processed to generate fragments with other properties; for example, C3-beta-c is also a chemoattractant [].This entry also includes complement C3-like proteins from snake venoms, such as AVF-1 and -2 from Austrelaps superbus, which have been shown to activate human complement Factor B in the presence of Factor D and Mg2+, and deplete the complement activity in human and guinea pig serum [].
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Publication
18558723 | -
First Author: Guldan H
Year: 2008
Journal: Biochemistry
Title: Identification and characterization of a bacterial glycerol-1-phosphate dehydrogenase: Ni(2+)-dependent AraM from Bacillus subtilis.
Volume: 47
Issue: 28
Pages: 7376-84
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Publication
10048922 | -
First Author: Sundberg E
Year: 1999
Journal: Nat Struct Biol
Title: Structural basis for HLA-DQ binding by the streptococcal superantigen SSA.
Volume: 6
Issue: 2
Pages: 123-9
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Publication
11934896 | -
First Author: Chi YI
Year: 2002
Journal: J Biol Chem
Title: Zinc-mediated dimerization and its effect on activity and conformation of staphylococcal enterotoxin type C.
Volume: 277
Issue: 25
Pages: 22839-46
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Publication
10986116 | -
First Author: Hâkansson M
Year: 2000
Journal: J Mol Biol
Title: The crystal structure of staphylococcal enterotoxin H: implications for binding properties to MHC class II and TcR molecules.
Volume: 302
Issue: 3
Pages: 527-37
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Publication
7628431 | -
First Author: Schad EM
Year: 1995
Journal: EMBO J
Title: Crystal structure of the superantigen staphylococcal enterotoxin type A.
Volume: 14
Issue: 14
Pages: 3292-301
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Publication
10860729 | -
First Author: Arcus VL
Year: 2000
Journal: J Mol Biol
Title: Conservation and variation in superantigen structure and activity highlighted by the three-dimensional structures of two new superantigens from Streptococcus pyogenes.
Volume: 299
Issue: 1
Pages: 157-68
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Publication
11045630 | -
First Author: Earhart CA
Year: 2000
Journal: Protein Sci
Title: Structure of streptococcal pyrogenic exotoxin A reveals a novel metal cluster.
Volume: 9
Issue: 9
Pages: 1847-51
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Publication
9253413 | -
First Author: Roussel A
Year: 1997
Journal: Nat Struct Biol
Title: Crystal structure of the streptococcal superantigen SPE-C: dimerization and zinc binding suggest a novel mode of interaction with MHC class II molecules.
Volume: 4
Issue: 8
Pages: 635-43
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Publication
15247241 | -
First Author: Baker HM
Year: 2004
Journal: J Biol Chem
Title: Crystallographic and mutational data show that the streptococcal pyrogenic exotoxin J can use a common binding surface for T-cell receptor binding and dimerization.
Volume: 279
Issue: 37
Pages: 38571-6
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Publication
14559915 | -
First Author: Papageorgiou AC
Year: 2004
Journal: J Biol Chem
Title: Identification of a secondary zinc-binding site in staphylococcal enterotoxin C2. Implications for superantigen recognition.
Volume: 279
Issue: 2
Pages: 1297-303
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Publication
8759320 | -
First Author: Papageorgiou AC
Year: 1996
Journal: J Mol Biol
Title: The refined crystal structure of toxic shock syndrome toxin-1 at 2.07 A resolution.
Volume: 260
Issue: 4
Pages: 553-69
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Publication
8225386 | -
First Author: Schwaeble W
Year: 1993
Journal: Immunobiology
Title: Human complement factor B: functional properties of a recombinant zymogen of the alternative activation pathway convertase.
Volume: 188
Issue: 3
Pages: 221-32
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Publication
21394116 | -
First Author: Bradley DT
Year: 2011
Journal: Eye (Lond)
Title: Complement in age-related macular degeneration: a focus on function.
Volume: 25
Issue: 6
Pages: 683-93
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Protein Domain
IPR016091 | SuperAg_toxin_C
Type: Homologous_superfamily
Description: This entry represents superantigen toxins from Staphylococcus aureus and Streptococcus pyogenes, which share a common core structure consisting of beta(2)-α-β(2). S. aureus toxins with this fold include: enterotoxins A (SEA) [], B (SEB) [], C2 (SEC2) [], C3 (SEC3) []and H (SEH) [], heat shock syndrome toxin-1 [], and superantigen-like proteins SET1 []and SET3 []. S. pyogenes toxins with this fold include: pyrogenic exotoxins A1 []and Spe-J [], and in superantigen proteins Spe-C [], Spe-H [], Smez-2 []and SSA [].
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Protein Domain
IPR004004 | Helic/Pol/Pept_Calicivir-typ
Type: Family
Description: Caliciviruses are positive-stranded ssRNA viruses that cause gastroenteritis []. The calicivirus genome contains two open reading frames, ORF1 and ORF2 [, ]. ORF1 encodes a non-structural polypeptide, which has RNA helicase, cysteine protease and RNA polymerase activity. The cysteine peptidases of the Calciviruses belong to MEROPS peptidase families C3 (subfamilies A to G), C24, C28, C37 and C40. The regions of the poly-protein in which these activities lie are similar to proteins produced by the picornaviruses [, ].
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Protein Domain
IPR028341 | Complement_B
Type: Family
Description: This group represents a complement factor B. Factor B is part of the alternate pathway of the complement system. It is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation [, ].
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Protein Domain
IPR003739 | Lys_aminomutase/Glu_NH3_mut
Type: Family
Description: This entry represents the lysine-2,3-aminomutase (LAM) family of proteins. LAM catalyses the interconversion of L-alpha-lysine and L-beta-lysine, which proceeds by migration of the amino group from C2 to C3 concomitant with cross-migration of the 3-pro-R hydrogen of L-alpha-lysine to the 2-pro-R position of L-beta-lysine. Glutamate 2,3-aminomutase is closely related to LAM, but can be distinguished by architecture (longer N-terminal region, shorter C-terminal region) and replacement of key lysine-binding residues []. Glutamate 2,3-aminomutase catalyses the interconversion of L-glutamate and L-beta-glutamate [].
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Protein
Q3V3N8
Organism: Mus musculus/domesticus
Length: 122  
Fragment?: false
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Publication
3881803 | -
First Author: Mathews FS
Year: 1985
Journal: Prog Biophys Mol Biol
Title: The structure, function and evolution of cytochromes.
Volume: 45
Issue: 1
Pages: 1-56
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Publication
11551953 | -
First Author: Louro RO
Year: 2001
Journal: J Biol Chem
Title: Conformational component in the coupled transfer of multiple electrons and protons in a monomeric tetraheme cytochrome.
Volume: 276
Issue: 47
Pages: 44044-51
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Publication
11939777 | -
First Author: Brigé A
Year: 2002
Journal: Biochemistry
Title: The 1.25 A resolution structure of the diheme NapB subunit of soluble nitrate reductase reveals a novel cytochrome c fold with a stacked heme arrangement.
Volume: 41
Issue: 15
Pages: 4827-36
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Protein Domain
IPR036280 | Multihaem_cyt_sf
Type: Homologous_superfamily
Description: In proteins belonging to the c-type cytochrome family [], the haem group is covalently attached by thioether bonds to two conserved cysteine residues located in the cytochrome c centre. Cytochromes c typically function in electron transfer, but c-type cytochrome centres are also found in the active sites of many enzymes.This domain contains multiple CxxCH motifs. There are a variable number of helices, as well as a little beta structure present in multihaem cytochromes, but they do not form a true structural fold. Cytochrome (cyt) c3-like proteins are multihaem cytochromes, including cyt c3 with four haem groups [], cyt c7 (cyt c551.5) with three haem groups (deletion of one cyt c3 haem-binding site), nine-haem cyt c (tandem repeat of two cyt c3-like domains with an additional haem-binding site), and 16-haem cyt c HmcA (tandem repeat of four cyt c3-like domains). The photosynthetic reaction centre composed of a cytochrome subunit is also a multihaem cytochrome []. In addition, the di-haem elbow motif shows a similar structure, the main characteristic feature of this motif being the packing of its two haems; many members of this group of proteins contain one or more complete motifs flanked by incomplete motifs and/or other domains. For example, the di-haem elbow motif is present in the multihaem cytochrome domain found in the periplasmic nitrate reductase subunit NapB [], in hydroxylamine oxioreductase HAO (contains 3 complete motifs), in cyt c554 (contains one complete motif), in cyt c nitrite reductase, and in the N-terminal domain of flavocytochrome c3 (respiratory fumarate reductase).
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Publication
14645204 | J:87688
First Author: Abmayr S
Year: 2004
Journal: Hum Mol Genet
Title: Characterization of ARC, apoptosis repressor interacting with CARD, in normal and dystrophin-deficient skeletal muscle.
Volume: 13
Issue: 2
Pages: 213-21
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Publication
15716419 | J:98227
First Author: Miyamoto Y
Year: 2005
Journal: J Neurosci
Title: Hippocampal synaptic modulation by the phosphotyrosine adapter protein ShcC/N-Shc via interaction with the NMDA receptor.
Volume: 25
Issue: 7
Pages: 1826-35
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Publication
11163269 | J:66508
First Author: Sakai R
Year: 2000
Journal: Neuron
Title: The mammalian ShcB and ShcC phosphotyrosine docking proteins function in the maturation of sensory and sympathetic neurons.
Volume: 28
Issue: 3
Pages: 819-33
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Publication
26786414 | J:259892
 
First Author: Campbell DP
Year: 2016
Journal: Sci Rep
Title: Canonical Notch signaling plays an instructive role in auditory supporting cell development.
Volume: 6
Pages: 19484
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Publication
20197277 | J:162595
First Author: Francisco AB
Year: 2010
Journal: J Biol Chem
Title: Deficiency of suppressor enhancer Lin12 1 like (SEL1L) in mice leads to systemic endoplasmic reticulum stress and embryonic lethality.
Volume: 285
Issue: 18
Pages: 13694-703
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Publication
11409899 | J:70024
First Author: Kojima T
Year: 2001
Journal: Biochem Biophys Res Commun
Title: Genomic organization of the Shc-related phosphotyrosine adapters and characterization of the full-length Sck/ShcB: specific association of p68-Sck/ShcB with pp135.
Volume: 284
Issue: 4
Pages: 1039-47
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Publication
19943849 | J:157011
First Author: Hryciw T
Year: 2010
Journal: J Neurochem
Title: The fibroblast growth factor receptor substrate 3 adapter is a developmentally regulated microtubule-associated protein expressed in migrating and differentiated neurons.
Volume: 112
Issue: 4
Pages: 924-39
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Publication
25706271 | J:226305
First Author: Romand R
Year: 2015
Journal: PLoS One
Title: Integrated annotation and analysis of in situ hybridization images using the ImAnno system: application to the ear and sensory organs of the fetal mouse.
Volume: 10
Issue: 2
Pages: e0118024
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HT Experiment
E-GEOD-2172 | Transcription profiling of mouse interleukin-10-deficient model for inflammatory bowel disease in C57Bl/6J and C3H/HeJBir strain backgrounds
Series Id: GSE2172
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
15459201 | J:95168
First Author: Allende ML
Year: 2004
Journal: J Biol Chem
Title: Mice deficient in sphingosine kinase 1 are rendered lymphopenic by FTY720.
Volume: 279
Issue: 50
Pages: 52487-92
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Publication
27806293 | J:240895
First Author: Young MM
Year: 2016
Journal: Cell Rep
Title: Sphingosine Kinase 1 Cooperates with Autophagy to Maintain Endocytic Membrane Trafficking.
Volume: 17
Issue: 6
Pages: 1532-1545
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Strain
MGI:6113590 | B6.129S4-C3<tm1Crr>/J
Attribute String: mutant strain, congenic, targeted mutation
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Strain
MGI:3785465 | B6.129S4-C3<tm1Crr>
Attribute String: targeted mutation, congenic
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Strain
MGI:6112619 | D2.129S4(B6)-C3<tm1Crr>/SjJ
Attribute String: targeted mutation, mutant strain, congenic
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Strain
MGI:2165043 | B6;129S4-C3<tm1Crr>/J
Attribute String: targeted mutation, mutant stock
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Strain
MGI:4941736 | B6.129S4-C3<tm1Crr>/JAnuApb
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:3842808 | D1.129P2-C3<tm1Pkna>
Attribute String: targeted mutation, congenic
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Strain
MGI:4834224 | FVB-Tg(C3-1-TAg)cJeg/JegJ
Attribute String: coisogenic, mutant strain, transgenic
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Strain
MGI:4431202 | FVB/N-Tg(C3-1-TAg)cJeg
Attribute String: coisogenic, mutant strain, transgenic
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Strain
MGI:2164433 | B10.D2-Tg(C3-1-TAg)cJeg/J
Attribute String: congenic, mutant strain, transgenic
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Strain
MGI:2164462 | B6.FVB-Tg(C3-1-TAg)cJeg/J
Attribute String: congenic, mutant strain, transgenic
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Strain
MGI:5897217 | FVB/N-Tg(C3-1-TAg)cJeg/2JegJ
Attribute String: coisogenic, mutant strain, transgenic
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Strain
MGI:2164499 | FVB-Tg(C3-1-TAg)cJeg/J
Attribute String: mutant strain, transgenic
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Publication
7972041 | J:52786
First Author: Maroulakou IG
Year: 1994
Journal: Proc Natl Acad Sci U S A
Title: Prostate and mammary adenocarcinoma in transgenic mice carrying a rat C3(1) simian virus 40 large tumor antigen fusion gene.
Volume: 91
Issue: 23
Pages: 11236-40
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Publication
16585173 | J:108216
First Author: Huh JI
Year: 2006
Journal: Cancer Res
Title: Distinct tumor stage-specific inhibitory effects of 2-methoxyestradiol in a breast cancer mouse model associated with Id-1 expression.
Volume: 66
Issue: 7
Pages: 3495-503
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Publication
15728372 | J:97014
First Author: Gupta V
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Mullerian inhibiting substance suppresses tumor growth in the C3(1)T antigen transgenic mouse mammary carcinoma model.
Volume: 102
Issue: 9
Pages: 3219-24
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Publication
9811472 | J:50935
First Author: Liu ML
Year: 1998
Journal: Oncogene
Title: Amplification of Ki-ras and elevation of MAP kinase activity during mammary tumor progression in C3(1)/SV40 Tag transgenic mice.
Volume: 17
Issue: 18
Pages: 2403-11
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Publication
14713544 | J:88112
First Author: Verschoyle RD
Year: 2004
Journal: Toxicol Pathol
Title: Articular chondromatosis and chrondroid metaplasia in transgenic TAg mice.
Volume: 32
Issue: 1
Pages: 22-5
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Publication
15735042 | J:97030
First Author: Liu R
Year: 2005
Journal: Cancer Res
Title: Oncolytic herpes simplex virus vector therapy of breast cancer in C3(1)/SV40 T-antigen transgenic mice.
Volume: 65
Issue: 4
Pages: 1532-40
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Publication
11145697 | J:66851
First Author: Wigginton JM
Year: 2001
Journal: J Immunol
Title: Complete regression of established spontaneous mammary carcinoma and the therapeutic prevention of genetically programmed neoplastic transition by IL-12/pulse IL-2: induction of local T cell infiltration, Fas/Fas ligand gene expression, and mammary epithelial apoptosis.
Volume: 166
Issue: 2
Pages: 1156-68
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Publication
8674054 | J:72136
First Author: Shibata MA
Year: 1996
Journal: Cancer Res
Title: p53-independent apoptosis during mammary tumor progression in C3(1)/SV40 large T antigen transgenic mice: suppression of apoptosis during the transition from preneoplasia to carcinoma.
Volume: 56
Issue: 13
Pages: 2998-3003
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Publication
22500798 | J:186207
First Author: Duncan JS
Year: 2012
Journal: Cell
Title: Dynamic reprogramming of the kinome in response to targeted MEK inhibition in triple-negative breast cancer.
Volume: 149
Issue: 2
Pages: 307-21
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Publication
15592523 | J:96009
First Author: Huh JI
Year: 2005
Journal: Oncogene
Title: Inhibition of VEGF receptors significantly impairs mammary cancer growth in C3(1)/Tag transgenic mice through antiangiogenic and non-antiangiogenic mechanisms.
Volume: 24
Issue: 5
Pages: 790-800
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Publication
28759043 | J:250667
First Author: Heilmann K
Year: 2017
Journal: Oncogene
Title: Genome-wide screen for differentially methylated long noncoding RNAs identifies Esrp2 and lncRNA Esrp2-as regulated by enhancer DNA methylation with prognostic relevance for human breast cancer.
Volume: 36
Issue: 46
Pages: 6446-6461
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Publication
22045025 | J:179058
First Author: Akinsete JA
Year: 2012
Journal: Carcinogenesis
Title: Consumption of high ω-3 fatty acid diet suppressed prostate tumorigenesis in C3(1) Tag mice.
Volume: 33
Issue: 1
Pages: 140-8
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Publication
34958345 | J:322604
First Author: Elisia I
Year: 2022
Journal: Carcinogenesis
Title: A low-carbohydrate diet containing soy protein and fish oil reduces breast but not prostate cancer in C3(1)/Tag mice.
Volume: 43
Issue: 2
Pages: 115-125
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Publication
12840216 | J:85028
First Author: Kavanaugh C
Year: 2003
Journal: J Nutr
Title: The use of genetically altered mice for breast cancer prevention studies.
Volume: 133
Issue: 7 Suppl
Pages: 2404S-2409S
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Publication
9502400 | J:46513
First Author: Shibata MA
Year: 1998
Journal: Toxicol Pathol
Title: The C3(1)/SV40 T antigen transgenic mouse model of prostate and mammary cancer.
Volume: 26
Issue: 1
Pages: 177-82
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Publication
24324595 | J:209742
First Author: Meyer-Losic F
Year: 2013
Journal: PLoS One
Title: STX140, but not paclitaxel, inhibits mammary tumour initiation and progression in C3(1)/SV40 T/t-antigen transgenic mice.
Volume: 8
Issue: 12
Pages: e80305
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Publication
11156389 | J:66915
First Author: Yoshidome K
Year: 2000
Journal: Cancer Res
Title: Estrogen promotes mammary tumor development in C3(1)/SV40 large T-antigen transgenic mice: paradoxical loss of estrogen receptoralpha expression during tumor progression.
Volume: 60
Issue: 24
Pages: 6901-10
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Publication
10999763 | J:64491
First Author: Wu K
Year: 2000
Journal: Clin Cancer Res
Title: 9-cis-Retinoic acid suppresses mammary tumorigenesis in C3(1)-simian virus 40 T antigen-transgenic mice.
Volume: 6
Issue: 9
Pages: 3696-704
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Publication
35263365 | J:321841
First Author: Arora I
Year: 2022
Journal: PLoS One
Title: An integrated analysis of the effects of maternal broccoli sprouts exposure on transcriptome and methylome in prevention of offspring mammary cancer.
Volume: 17
Issue: 3
Pages: e0264858
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Publication
24382894 | J:213535
First Author: Brock A
Year: 2014
Journal: Sci Transl Med
Title: Silencing HoxA1 by intraductal injection of siRNA lipidoid nanoparticles prevents mammary tumor progression in mice.
Volume: 6
Issue: 217
Pages: 217ra2
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Publication
31260484 | J:277222
First Author: Daniels SR
Year: 2019
Journal: PLoS One
Title: Loss of function Cbl-c mutations in solid tumors.
Volume: 14
Issue: 7
Pages: e0219143
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Publication
12124322 | J:77958
First Author: Calvo A
Year: 2002
Journal: Cancer Res
Title: Adenovirus-mediated endostatin delivery results in inhibition of mammary gland tumor growth in C3(1)/SV40 T-antigen transgenic mice.
Volume: 62
Issue: 14
Pages: 3934-8
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Publication
10713685 | J:61011
First Author: Green JE
Year: 2000
Journal: Oncogene
Title: The C3(1)/SV40 T-antigen transgenic mouse model of mammary cancer: ductal epithelial cell targeting with multistage progression to carcinoma.
Volume: 19
Issue: 8
Pages: 1020-7
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Publication
21632555 | J:172717
First Author: O'Toole SA
Year: 2011
Journal: Cancer Res
Title: Hedgehog overexpression is associated with stromal interactions and predicts for poor outcome in breast cancer.
Volume: 71
Issue: 11
Pages: 4002-14
•
•
•
•
•
Publication
12010861 | J:77199
First Author: Wu K
Year: 2002
Journal: Cancer Epidemiol Biomarkers Prev
Title: Suppression of mammary tumorigenesis in transgenic mice by the RXR-selective retinoid, LGD1069.
Volume: 11
Issue: 5
Pages: 467-74
•
•
•
•
•
Publication
9472712 | J:45643
First Author: Shibata MA
Year: 1998
Journal: Carcinogenesis
Title: Altered expression of transforming growth factor betas during urethral and bulbourethral gland tumor progression in transgenic mice carrying the androgen-responsive C3(1) 5' flanking region fused to SV40 large T antigen.
Volume: 19
Issue: 1
Pages: 195-205
•
•
•
•
•
Publication
12907608 | J:84849
First Author: Wu Y
Year: 2003
Journal: Cancer Res
Title: Reduced circulating insulin-like growth factor I levels delay the onset of chemically and genetically induced mammary tumors.
Volume: 63
Issue: 15
Pages: 4384-8
•
•
•
•
•
Publication
27171183 | J:240994
First Author: Aprelikova O
Year: 2016
Journal: PLoS One
Title: Development and Preclinical Application of an Immunocompetent Transplant Model of Basal Breast Cancer with Lung, Liver and Brain Metastases.
Volume: 11
Issue: 5
Pages: e0155262
•
•
•
•
•
Publication
9428383 | J:45372
First Author: Jorcyk CL
Year: 1998
Journal: Prostate
Title: Development and characterization of a mouse prostate adenocarcinoma cell line: ductal formation determined by extracellular matrix.
Volume: 34
Issue: 1
Pages: 10-22
•
•
•
•
•
Publication
11606379 | J:72279
First Author: Green JE
Year: 2001
Journal: Cancer Res
Title: 2-difluoromethylornithine and dehydroepiandrosterone inhibit mammary tumor progression but not mammary or prostate tumor initiation in C3(1)/SV40 T/t-antigen transgenic mice.
Volume: 61
Issue: 20
Pages: 7449-55
•
•
•
•
•
Publication
37686596 | J:340318
 
First Author: Bustamante-Marin X
Year: 2023
Journal: Cancers (Basel)
Title: Regulation of IGF1R by MicroRNA-15b Contributes to the Anticancer Effects of Calorie Restriction in a Murine C3-TAg Model of Triple-Negative Breast Cancer.
Volume: 15
Issue: 17
•
•
•
•
•
Publication
16690748 | J:110207
First Author: Diwadkar-Navsariwala V
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Selenoprotein deficiency accelerates prostate carcinogenesis in a transgenic model.
Volume: 103
Issue: 21
Pages: 8179-84
•
•
•
•
•
Publication
12209972 | J:78871
First Author: Calvo A
Year: 2002
Journal: Int J Cancer
Title: Inhibition of the mammary carcinoma angiogenic switch in C3(1)/SV40 transgenic mice by a mutated form of human endostatin.
Volume: 101
Issue: 3
Pages: 224-34
•
•
•
•
•
Publication
38802425 | J:348783
First Author: Rahman MM
Year: 2024
Journal: Sci Rep
Title: A novel combinatorial approach using sulforaphane- and withaferin A-rich extracts for prevention of estrogen receptor-negative breast cancer through epigenetic and gut microbial mechanisms.
Volume: 14
Issue: 1
Pages: 12091
•
•
•
•
•
Publication
36611809 | J:332507
 
First Author: Arora I
Year: 2022
Journal: Cells
Title: Genome-Wide Analysis on Transcriptome and Methylome in Prevention of Mammary Tumor Induced by Early Life Combined Botanicals.
Volume: 12
Issue: 1
•
•
•
•
•
Publication
25354395 | J:223090
First Author: Sundaram S
Year: 2014
Journal: PLoS One
Title: Obesity-mediated regulation of HGF/c-Met is associated with reduced basal-like breast cancer latency in parous mice.
Volume: 9
Issue: 10
Pages: e111394
•
•
•
•
•
Publication
15781642 | J:97163
First Author: Cha TL
Year: 2005
Journal: Cancer Res
Title: Emodin down-regulates androgen receptor and inhibits prostate cancer cell growth.
Volume: 65
Issue: 6
Pages: 2287-95
•
•
•
•
•
Publication
12663504 | J:82837
First Author: Shibata MA
Year: 2003
Journal: Carcinogenesis
Title: Comparative effects of lovastatin on mammary and prostate oncogenesis in transgenic mouse models.
Volume: 24
Issue: 3
Pages: 453-9
•
•
•
•
•
Publication
10498897 | J:57996
First Author: Maroulakou IG
Year: 1999
Journal: Oncogene
Title: Heterotopic endochondrial ossification with mixed tumor formation in C3(1)/Tag transgenic mice is associated with elevated TGF-beta1 and BMP-2 expression.
Volume: 18
Issue: 39
Pages: 5435-47
•
•
•
•
•
Publication
8895741 | J:72324
First Author: Shibata MA
Year: 1996
Journal: Cancer Res
Title: Progression of prostatic intraepithelial neoplasia to invasive carcinoma in C3(1)/SV40 large T antigen transgenic mice: histopathological and molecular biological alterations.
Volume: 56
Issue: 21
Pages: 4894-903
•
•
•
•
•
Publication
29324859 | J:258381
First Author: He D
Year: 2018
Journal: PLoS One
Title: Magnetic resonance spectroscopy detects differential lipid composition in mammary glands on low fat, high animal fat versus high fructose diets.
Volume: 13
Issue: 1
Pages: e0190929
•
•
•
•
•
Publication
15111774 | J:90175
First Author: Wild R
Year: 2004
Journal: Breast Cancer Res Treat
Title: VEGF-DT385 toxin conjugate inhibits mammary adenocarcinoma development in a transgenic mouse model of spontaneous tumorigenesis.
Volume: 85
Issue: 2
Pages: 161-71
•
•
•
•
•
Publication
14706566 | J:88119
First Author: Moody TW
Year: 2004
Journal: Life Sci
Title: VIP receptor antagonists inhibit mammary carcinogenesis in C3(1)SV40T antigen mice.
Volume: 74
Issue: 11
Pages: 1345-57
•
•
•
•
•




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