| Type |
Details |
Score |
| Publication |
| First Author: |
Huang L |
| Year: |
2015 |
| Journal: |
Neuroscience |
| Title: |
Congenital absence of corticospinal tract does not severely affect plastic changes of the developing postnatal spinal cord. |
| Volume: |
301 |
|
| Pages: |
338-50 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Liu A |
| Year: |
2023 |
| Journal: |
Glia |
| Title: |
Celsr2-mediated morphological polarization and functional phenotype of reactive astrocytes in neural repair. |
| Volume: |
71 |
| Issue: |
8 |
| Pages: |
1985-2004 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nandrot EF |
| Year: |
2007 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Essential role for MFG-E8 as ligand for alphavbeta5 integrin in diurnal retinal phagocytosis. |
| Volume: |
104 |
| Issue: |
29 |
| Pages: |
12005-10 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Michalski MN |
| Year: |
2018 |
| Journal: |
FASEB J |
| Title: |
Inflammatory bone loss associated with MFG-E8 deficiency is rescued by teriparatide. |
| Volume: |
32 |
| Issue: |
7 |
| Pages: |
3730-3741 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ait-Oufella H |
| Year: |
2007 |
| Journal: |
Circulation |
| Title: |
Lactadherin deficiency leads to apoptotic cell accumulation and accelerated atherosclerosis in mice. |
| Volume: |
115 |
| Issue: |
16 |
| Pages: |
2168-77 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wu S |
| Year: |
2008 |
| Journal: |
Nat Protoc |
| Title: |
A protocol for constructing gene targeting vectors: generating knockout mice for the cadherin family and beyond. |
| Volume: |
3 |
| Issue: |
6 |
| Pages: |
1056-76 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
737
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yahata Y |
| Year: |
2006 |
| Journal: |
J Biol Chem |
| Title: |
A novel function of angiotensin II in skin wound healing. Induction of fibroblast and keratinocyte migration by angiotensin II via heparin-binding epidermal growth factor (EGF)-like growth factor-mediated EGF receptor transactivation. |
| Volume: |
281 |
| Issue: |
19 |
| Pages: |
13209-16 |
|
•
•
•
•
•
|
| GO Term |
|
•
•
•
•
•
|
| GO Term |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1147
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1091
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1061
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1095
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
934
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Choi JH |
| Year: |
2004 |
| Journal: |
J Cell Sci |
| Title: |
Sorting nexin 16 regulates EGF receptor trafficking by phosphatidylinositol-3-phosphate interaction with the Phox domain. |
| Volume: |
117 |
| Issue: |
Pt 18 |
| Pages: |
4209-18 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sato-Nishiuchi R |
| Year: |
2023 |
| Journal: |
J Cell Biol |
| Title: |
Polydom/SVEP1 binds to Tie1 and promotes migration of lymphatic endothelial cells. |
| Volume: |
222 |
| Issue: |
9 |
|
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1581
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1607
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1537
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1607
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Basta LP |
| Year: |
2022 |
| Journal: |
Front Cell Dev Biol |
| Title: |
Celsr1 and Celsr2 exhibit distinct adhesive interactions and contributions to planar cell polarity. |
| Volume: |
10 |
|
| Pages: |
1064907 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
686
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Allele |
| Name: |
cadherin, EGF LAG seven-pass G-type receptor 1; spin cycle |
| Allele Type: |
Chemically induced (ENU) |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
cadherin, EGF LAG seven-pass G-type receptor 1; wild type |
|
|
|
•
•
•
•
•
|
| Allele |
| Name: |
cadherin, EGF LAG seven-pass G-type receptor 2; wild type |
|
|
|
•
•
•
•
•
|
| Allele |
| Name: |
cadherin, EGF LAG seven-pass G-type receptor 3; wild type |
|
|
|
•
•
•
•
•
|
| Allele |
| Name: |
cadherin, EGF LAG seven-pass G-type receptor 1; crash |
| Allele Type: |
Chemically induced (ENU) |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
collagen and calcium binding EGF domains 1; wild type |
|
|
|
•
•
•
•
•
|
| Allele |
| Name: |
von Willebrand factor C and EGF domains; wild type |
| Allele Type: |
Not Specified |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
delta/notch-like EGF repeat containing; targeted mutation 1, Hiroshi Takeshima |
| Allele Type: |
Targeted |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
| Allele |
| Name: |
von Willebrand factor D and EGF domains; wild type |
| Allele Type: |
Not Specified |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
delta/notch-like EGF repeat containing; targeted mutation 1, Velocigene |
| Allele Type: |
Targeted |
| Attribute String: |
Null/knockout, Reporter |
|
•
•
•
•
•
|
| Allele |
| Name: |
EGF domain specific O-linked N-acetylglucosamine transferase; wild type |
| Allele Type: |
Not Specified |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
EGF domain specific O-linked N-acetylglucosamine transferase; endonuclease-mediated mutation 1, Jackson |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
| Allele |
| Name: |
cadherin, EGF LAG seven-pass G-type receptor 1; curly tail bobber |
| Allele Type: |
Spontaneous |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
| Allele |
| Name: |
delta/notch-like EGF repeat containing; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Conditional ready, No functional change |
|
•
•
•
•
•
|
| Allele |
| Name: |
delta/notch-like EGF repeat containing; endonuclease-mediated mutation 5, GemPharmatech Co., Ltd |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
| Allele |
| Name: |
EGF domain specific O-linked N-acetylglucosamine transferase; endonuclease-mediated mutation 2, Jackson |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
| Allele |
| Name: |
delta/notch-like EGF repeat containing; endonuclease-mediated mutation 1, Julien Sage |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bonet F |
| Year: |
2022 |
| Journal: |
Int J Mol Sci |
| Title: |
CCBE1 Is Essential for Epicardial Function during Myocardium Development. |
| Volume: |
23 |
| Issue: |
20 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Miyanishi M |
| Year: |
2012 |
| Journal: |
Int Immunol |
| Title: |
Synergistic effect of Tim4 and MFG-E8 null mutations on the development of autoimmunity. |
| Volume: |
24 |
| Issue: |
9 |
| Pages: |
551-9 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1122
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
589
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
695
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ding Y |
| Year: |
2014 |
| Journal: |
PLoS One |
| Title: |
Functional motor recovery from motoneuron axotomy is compromised in mice with defective corticospinal projections. |
| Volume: |
9 |
| Issue: |
7 |
| Pages: |
e101918 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Han Q |
| Year: |
2015 |
| Journal: |
Exp Neurol |
| Title: |
Plasticity of motor network and function in the absence of corticospinal projection. |
| Volume: |
267 |
|
| Pages: |
194-208 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhou Y |
| Year: |
2018 |
| Journal: |
Cell Stem Cell |
| Title: |
Autocrine Mfge8 Signaling Prevents Developmental Exhaustion of the Adult Neural Stem Cell Pool. |
| Volume: |
23 |
| Issue: |
3 |
| Pages: |
444-452.e4 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
440
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Interaction Experiment |
| Description: |
A regulated interaction with the UIM protein Eps15 implicates parkin in EGF receptor trafficking and PI(3)K-Akt signalling. |
|
•
•
•
•
•
|
| Interaction Experiment |
| Description: |
An epidermal growth factor (EGF) -dependent interaction between GIT1 and sorting nexin 6 promotes degradation of the EGF receptor. |
|
•
•
•
•
•
|
| Interaction Experiment |
| Description: |
Tyrosine phosphorylation of the c-cbl proto-oncogene protein product and association with epidermal growth factor (EGF) receptor upon EGF stimulation. |
|
•
•
•
•
•
|
| Interaction Experiment |
| Description: |
The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSos1. |
|
•
•
•
•
•
|
| Interaction Experiment |
| Description: |
APP Binds to the EGFR Ligands HB-EGF and EGF, Acting Synergistically with EGF to Promote ERK Signaling and Neuritogenesis. |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yang C |
| Year: |
2011 |
| Journal: |
Cancer Res |
| Title: |
The integrin alpha(v)beta(3-5) ligand MFG-E8 is a p63/p73 target gene in triple-negative breast cancers but exhibits suppressive functions in ER(+) and erbB2(+) breast cancers. |
| Volume: |
71 |
| Issue: |
3 |
| Pages: |
937-45 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Akman HB |
| Year: |
2015 |
| Journal: |
Hum Mol Genet |
| Title: |
3'UTR shortening and EGF signaling: implications for breast cancer. |
| Volume: |
24 |
| Issue: |
24 |
| Pages: |
6910-20 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wu WJ |
| Year: |
2003 |
| Journal: |
Cell |
| Title: |
Activated Cdc42 sequesters c-Cbl and prevents EGF receptor degradation. |
| Volume: |
114 |
| Issue: |
6 |
| Pages: |
715-25 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mizutani A |
| Year: |
2010 |
| Journal: |
J Biochem |
| Title: |
Arkadia complexes with clathrin adaptor AP2 and regulates EGF signalling. |
| Volume: |
148 |
| Issue: |
6 |
| Pages: |
733-41 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Adrain C |
| Year: |
2011 |
| Journal: |
EMBO Rep |
| Title: |
Mammalian EGF receptor activation by the rhomboid protease RHBDL2. |
| Volume: |
12 |
| Issue: |
5 |
| Pages: |
421-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bover O |
| Year: |
2018 |
| Journal: |
PLoS One |
| Title: |
Loss of Ccbe1 affects cardiac-specification and cardiomyocyte differentiation in mouse embryonic stem cells. |
| Volume: |
13 |
| Issue: |
10 |
| Pages: |
e0205108 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Camaj P |
| Year: |
2009 |
| Journal: |
Biol Chem |
| Title: |
EFEMP1 binds the EGF receptor and activates MAPK and Akt pathways in pancreatic carcinoma cells. |
| Volume: |
390 |
| Issue: |
12 |
| Pages: |
1293-302 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mei J |
| Year: |
2018 |
| Journal: |
Sci Rep |
| Title: |
Body temperature measurement in mice during acute illness: implantable temperature transponder versus surface infrared thermometry. |
| Volume: |
8 |
| Issue: |
1 |
| Pages: |
3526 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Khalifeh-Soltani A |
| Year: |
2016 |
| Journal: |
JCI Insight |
| Title: |
Mfge8 regulates enterocyte lipid storage by promoting enterocyte triglyceride hydrolase activity. |
| Volume: |
1 |
| Issue: |
18 |
| Pages: |
e87418 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Freeman M |
| Year: |
1994 |
| Journal: |
Mech Dev |
| Title: |
The spitz gene is required for photoreceptor determination in the Drosophila eye where it interacts with the EGF receptor. |
| Volume: |
48 |
| Issue: |
1 |
| Pages: |
25-33 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yates LL |
| Year: |
2010 |
| Journal: |
Hum Mol Genet |
| Title: |
The PCP genes Celsr1 and Vangl2 are required for normal lung branching morphogenesis. |
| Volume: |
19 |
| Issue: |
11 |
| Pages: |
2251-67 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Brzóska HŁ |
| Year: |
2016 |
| Journal: |
Kidney Int |
| Title: |
Planar cell polarity genes Celsr1 and Vangl2 are necessary for kidney growth, differentiation, and rostrocaudal patterning. |
| Volume: |
90 |
| Issue: |
6 |
| Pages: |
1274-1284 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ying G |
| Year: |
2009 |
| Journal: |
Mol Cell Biol |
| Title: |
The protocadherin gene Celsr3 is required for interneuron migration in the mouse forebrain. |
| Volume: |
29 |
| Issue: |
11 |
| Pages: |
3045-61 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Karpanen T |
| Year: |
2017 |
| Journal: |
Circ Res |
| Title: |
An Evolutionarily Conserved Role for Polydom/Svep1 During Lymphatic Vessel Formation. |
| Volume: |
120 |
| Issue: |
8 |
| Pages: |
1263-1275 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhu C |
| Year: |
2019 |
| Journal: |
Neurobiol Aging |
| Title: |
Unaltered prion disease in mice lacking developmental endothelial locus-1. |
| Volume: |
76 |
|
| Pages: |
208-213 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wen Q |
| Year: |
2022 |
| Journal: |
Brain |
| Title: |
Inactivating Celsr2 promotes motor axon fasciculation and regeneration in mouse and human. |
| Volume: |
145 |
| Issue: |
2 |
| Pages: |
670-683 |
|
•
•
•
•
•
|
| GO Term |
|
•
•
•
•
•
|
| GO Term |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ye H |
| Year: |
2013 |
| Journal: |
Biochim Biophys Acta |
| Title: |
NMR solution structure of C2 domain of MFG-E8 and insights into its molecular recognition with phosphatidylserine. |
| Volume: |
1828 |
| Issue: |
3 |
| Pages: |
1083-93 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Rebay I |
| Year: |
1991 |
| Journal: |
Cell |
| Title: |
Specific EGF repeats of Notch mediate interactions with Delta and Serrate: implications for Notch as a multifunctional receptor. |
| Volume: |
67 |
| Issue: |
4 |
| Pages: |
687-99 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jia Z |
| Year: |
2014 |
| Journal: |
Mol Cell Biol |
| Title: |
Regulation of the protocadherin Celsr3 gene and its role in globus pallidus development and connectivity. |
| Volume: |
34 |
| Issue: |
20 |
| Pages: |
3895-910 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
332
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
835
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
546
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nakaya M |
| Year: |
2013 |
| Journal: |
Nat Commun |
| Title: |
GRK6 deficiency in mice causes autoimmune disease due to impaired apoptotic cell clearance. |
| Volume: |
4 |
|
| Pages: |
1532 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sargeant TJ |
| Year: |
2014 |
| Journal: |
Nat Cell Biol |
| Title: |
Stat3 controls cell death during mammary gland involution by regulating uptake of milk fat globules and lysosomal membrane permeabilization. |
| Volume: |
16 |
| Issue: |
11 |
| Pages: |
1057-1068 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ruggiero L |
| Year: |
2012 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Diurnal, localized exposure of phosphatidylserine by rod outer segment tips in wild-type but not Itgb5-/- or Mfge8-/- mouse retina. |
| Volume: |
109 |
| Issue: |
21 |
| Pages: |
8145-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ravni A |
| Year: |
2009 |
| Journal: |
J Invest Dermatol |
| Title: |
Planar cell polarity cadherin Celsr1 regulates skin hair patterning in the mouse. |
| Volume: |
129 |
| Issue: |
10 |
| Pages: |
2507-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang F |
| Year: |
2017 |
| Journal: |
Neuroscience |
| Title: |
The role of Celsr3 in the development of central somatosensory projections from dorsal root ganglia. |
| Volume: |
359 |
|
| Pages: |
267-276 |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus caroli |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus caroli |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|