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Search results 1801 to 1900 out of 2795 for Egfr

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Type Details Score
Publication
24381249 | J:204277
 
First Author: Sauvageau M
Year: 2013
Journal: Elife
Title: Multiple knockout mouse models reveal lincRNAs are required for life and brain development.
Volume: 2
Pages: e01749
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GO Term
GO:0070436 | Grb2-EGFR complex
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GO Term
GO:0070435 | Shc-EGFR complex
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Protein Coding Gene
MGI:2443160 | Pag1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:105307 | Ptpn3
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:104673 | Ptpn12
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1333763 | Epn1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:104582 | Eps15l1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q60902
Organism: Mus musculus/domesticus
Length: 907  
Fragment?: false
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Protein
A2ALK8
Organism: Mus musculus/domesticus
Length: 913  
Fragment?: false
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Protein
Q3U1F9
Organism: Mus musculus/domesticus
Length: 429  
Fragment?: false
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Protein
Q80VP1
Organism: Mus musculus/domesticus
Length: 575  
Fragment?: false
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Protein
P35831
Organism: Mus musculus/domesticus
Length: 775  
Fragment?: false
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HT Experiment
GSE142113 | Targeting Fibroblast growth factor-23 (FGF23)-responsive pathways in the control of phosphate and vitamin D metabolism
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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Strain
MGI:6144449 | STOCK Col1a1<tm1(CAG-EGFR)Char>/Nci
Attribute String: mutant stock, targeted mutation
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Allele
Tg(Prl-EGFR)#Sme | MGI:5696741
Name: transgene insertion, Shlomo Melmed
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Genotype
Genotype
Symbol: Tg(EGFR)3Jlj/?
Background: involves: C57BL/6 * DBA/2
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(EGFR)4Jlj/?
Background: involves: C57BL/6 * DBA/2
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(EGFR)5Jlj/?
Background: involves: C57BL/6 * DBA/2
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(EGFR)0Jlj/?
Background: involves: C57BL/6 * DBA/2
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(EGFR)1Jlj/?
Background: involves: C57BL/6 * DBA/2
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(EGFR)2Jlj/?
Background: involves: C57BL/6 * DBA/2
Zygosity: ot
Has Mutant Allele: true
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Publication
23027125 | -
First Author: Hartman Z
Year: 2013
Journal: Oncogene
Title: HER2 stabilizes EGFR and itself by altering autophosphorylation patterns in a manner that overcomes regulatory mechanisms and promotes proliferative and transformation signaling.
Volume: 32
Issue: 35
Pages: 4169-80
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GO Term
GO:0042059 | negative regulation of epidermal growth factor receptor signaling pathway
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GO Term
GO:0045742 | positive regulation of epidermal growth factor receptor signaling pathway
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GO Term
GO:0045741 | positive regulation of epidermal growth factor-activated receptor activity
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GO Term
GO:0007175 | negative regulation of epidermal growth factor-activated receptor activity
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Publication
25909911 | J:233815
First Author: Lai KM
Year: 2015
Journal: PLoS One
Title: Diverse Phenotypes and Specific Transcription Patterns in Twenty Mouse Lines with Ablated LincRNAs.
Volume: 10
Issue: 4
Pages: e0125522
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Protein
Q99JZ7
Organism: Mus musculus/domesticus
Length: 461  
Fragment?: false
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Protein
Q3TJN8
Organism: Mus musculus/domesticus
Length: 461  
Fragment?: false
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Protein
Q3TK48
Organism: Mus musculus/domesticus
Length: 461  
Fragment?: false
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GO Term
GO:0070618 | Grb2-Sos complex
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GO Term
GO:0070619 | Shc-Grb2-Sos complex
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GO Term
GO:0070620 | EGFR-Grb2-Sos complex
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Protein Coding Gene
MGI:1919170 | Epgn
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:700010 | Sh3gl1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:104583 | Eps15
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:700011 | Sh3gl3
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2685362 | Fam83b
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q0VBM2
Organism: Mus musculus/domesticus
Length: 1012  
Fragment?: false
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Protein
P42567
Organism: Mus musculus/domesticus
Length: 897  
Fragment?: false
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Protein
Q62419
Organism: Mus musculus/domesticus
Length: 368  
Fragment?: false
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Protein
Q62421
Organism: Mus musculus/domesticus
Length: 347  
Fragment?: false
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Publication
8650580 | J:50499
First Author: Galcheva-Gargova Z
Year: 1996
Journal: Science
Title: Binding of zinc finger protein ZPR1 to the epidermal growth factor receptor.
Volume: 272
Issue: 5269
Pages: 1797-802
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Allele
Egfr<tm2(EGFR)Wag> | MGI:2673586
Name: epidermal growth factor receptor; targeted mutation 2, Erwin F Wagner
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence, Null/knockout
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Allele
Col1a1<tm2(CAG-EGFR*)Char> | MGI:3837826
Name: collagen, type I, alpha 1; targeted mutation 2, Al Charest
Allele Type: Targeted
Attribute String: Conditional ready, Humanized sequence, Inserted expressed sequence, No functional change
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Allele
Tg(Myh6-EGFR*)9-12Iko | MGI:5908353
Name: transgene insertion 9-12, Issei Komuro
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Col1a1<tm1(CAG-EGFR*T790M*C797S*L858R)Mje> | MGI:6256800
Name: collagen, type I, alpha 1; targeted mutation 1, Michael J Eck
Allele Type: Targeted
Attribute String: Conditional ready, Humanized sequence, Inserted expressed sequence
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Allele
Aqp5<tm2.1Niba> | MGI:6450543
Name: aquaporin 5; targeted mutation 2.1, Nick Barker
Allele Type: Targeted
Attribute String: Reporter
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Allele
Slc9a3<tm3.1Niba> | MGI:6450740
Name: solute carrier family 9 (sodium/hydrogen exchanger), member 3; targeted mutation 3.1, Nick Barker
Allele Type: Targeted
Attribute String: Reporter
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Strain
MGI:6354755 | C57BL/6JSmoc-Egfr<tm1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, targeted mutation
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Genotype
Genotype
Symbol: Tg(Prl-EGFR)#Sme/?
Background: Not Specified
Zygosity: ot
Has Mutant Allele: true
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Protein Coding Gene
MGI:98724 | Tgfa
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
24931608 | J:211778
First Author: Kawabata S
Year: 2014
Journal: Cell Rep
Title: Rapamycin prevents the development and progression of mutant epidermal growth factor receptor lung tumors with the acquired resistance mutation T790M.
Volume: 7
Issue: 6
Pages: 1824-32
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Publication
31935369 | J:283659
First Author: Kurppa KJ
Year: 2020
Journal: Cancer Cell
Title: Treatment-Induced Tumor Dormancy through YAP-Mediated Transcriptional Reprogramming of the Apoptotic Pathway.
Volume: 37
Issue: 1
Pages: 104-122.e12
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Publication
34853306 | J:316406
First Author: Gong K
Year: 2021
Journal: Nat Commun
Title: Comprehensive targeting of resistance to inhibition of RTK signaling pathways by using glucocorticoids.
Volume: 12
Issue: 1
Pages: 7014
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GO Term
GO:0038137 | ERBB4-EGFR signaling pathway
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GO Term
GO:0070621 | EGFR-Shc-Grb2-Sos complex
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Protein Coding Gene
MGI:88068 | Areg
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:107809 | Aamp
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1345138 | Spry2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:97010 | Mmp3
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
P28862
Organism: Mus musculus/domesticus
Length: 477  
Fragment?: false
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Protein
Q9QXV8
Organism: Mus musculus/domesticus
Length: 315  
Fragment?: false
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Protein
J3QN89
Organism: Mus musculus/domesticus
Length: 436  
Fragment?: false
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Publication
21518868 | J:172194
First Author: Guo C
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: FER tyrosine kinase (FER) overexpression mediates resistance to quinacrine through EGF-dependent activation of NF-kappaB.
Volume: 108
Issue: 19
Pages: 7968-73
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GO Term
GO:1905251 | epidermal growth factor receptor signaling pathway involved in heart process
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Protein Coding Gene
MGI:96070 | Hbegf
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:99439 | Btc
Type: protein_coding_gene
Organism: mouse, laboratory
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Allele
Egfr<Wa5> | MGI:2178387
 
Name: epidermal growth factor receptor; waved 5
Allele Type: Chemically induced (ENU)
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Allele
Tg(tetO-EGFR*L858R)56Hev | MGI:3690078
Name: transgene insertion 56, Harold E Varmus
Allele Type: Transgenic
Attribute String: Inducible, Inserted expressed sequence
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Allele
Tg(tetO-EGFR*delta19)11Hev | MGI:3690457
Name: transgene insertion 11, Harold E Varmus
Allele Type: Transgenic
Attribute String: Humanized sequence, Inducible, Inserted expressed sequence
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Strain
MGI:6144450 | STOCK Col1a1<tm2(CAG-EGFR*)Char>/Nci
Attribute String: targeted mutation, mutant stock
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Allele
Tg(tetO-EGFR*L858R)#Hev | MGI:5449268
Name: transgene insertion, Harold E Varmus
Allele Type: Transgenic
Attribute String: Inducible, Inserted expressed sequence
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Allele
Tg(tetO-EGFR*T790M*L858R)19Kkw | MGI:5781130
Name: transgene insertion 19, Kwok-Kin Wong
Allele Type: Transgenic
Attribute String: Humanized sequence, Inducible, Inserted expressed sequence
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Publication
22216087 | J:182337
First Author: Fukushima N
Year: 2011
Journal: PLoS One
Title: A crucial role of activin A-mediated growth hormone suppression in mouse and human heart failure.
Volume: 6
Issue: 12
Pages: e27901
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Allele
Gt(ROSA)26Sor<tm1(CAG-Egfr*)Rnem> | MGI:7545194
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Raphael A Nemenoff
Allele Type: Targeted
Attribute String: Conditional ready, Inserted expressed sequence, Reporter
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Strain
MGI:7545196 | C57BL/6-Gt(ROSA)26Sor<tm1(CAG-Egfr*)Rnem>/J
Attribute String: mutant strain, coisogenic, targeted mutation
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Allele
Gt(ROSA)26Sor<tm2(CAG-Egfr*L860R)Rnem> | MGI:7545201
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 2, Raphael A Nemenoff
Allele Type: Targeted
Attribute String: Conditional ready, Humanized sequence, Inserted expressed sequence, Reporter
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Genotype
Genotype
Symbol: Egfr/Egfr
Background: involves: 129/Sv * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Egfr/Egfr
Background: involves: 129
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Myh6-EGFR*)9-12Iko/?
Background: involves: C57BL/6 * DBA/2
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Col1a1/Col1a1<+>
Background: involves: 129S4/SvJae * BALB/c * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Publication
33506575 | J:305973
First Author: Isomura H
Year: 2021
Journal: Cancer Sci
Title: Conditional Ror1 knockout reveals crucial involvement in lung adenocarcinoma development and identifies novel HIF-1α regulator.
Volume: 112
Issue: 4
Pages: 1614-1623
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Publication
23572183 | J:349070
First Author: Nakano T
Year: 2014
Journal: Clin Transl Oncol
Title: Diacylglycerol kinase η modulates oncogenic properties of lung cancer cells.
Volume: 16
Issue: 1
Pages: 29-35
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Publication
37929799 | J:342588
 
First Author: Hsu WL
Year: 2023
Journal: Dis Model Mech
Title: High-fat diet induces C-reactive protein secretion, promoting lung adenocarcinoma via immune microenvironment modulation.
Volume: 16
Issue: 11
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Publication
26036643 | J:230522
First Author: Tricker EM
Year: 2015
Journal: Cancer Discov
Title: Combined EGFR/MEK Inhibition Prevents the Emergence of Resistance in EGFR-Mutant Lung Cancer.
Volume: 5
Issue: 9
Pages: 960-971
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HT Experiment
E-GEOD-3915 | Transcription profiling of mouse PKCa -/- mutant vs. wild type small intestine
Series Id: GSE3915
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
38049664 | J:346208
First Author: Caswell DR
Year: 2024
Journal: Nat Genet
Title: The role of APOBEC3B in lung tumor evolution and targeted cancer therapy resistance.
Volume: 56
Issue: 1
Pages: 60-73
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Protein
D3Z3U7
Organism: Mus musculus/domesticus
Length: 550  
Fragment?: false
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Protein Coding Gene
MGI:108088 | Gab1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:104681 | Hgs
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1329014 | Stam
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1929100 | Stam2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:700009 | Sh3gl2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:108295 | Pxn
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1889583 | Sh3kbp1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q924X1
Organism: Mus musculus/domesticus
Length: 152  
Fragment?: false
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Protein
Q99LI8
Organism: Mus musculus/domesticus
Length: 775  
Fragment?: false
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Protein
Q8VI36
Organism: Mus musculus/domesticus
Length: 591  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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