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Search results 1801 to 1900 out of 1988 for Gata3

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Type Details Score
Genotype
Genotype
Symbol: Gata3/Gata3<+>
Background: involves: 129S7/SvEvBrd * C57BL/6 * FVB/N
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gata3/Gata3<+>
Background: FVB.129(B6)-Gata3
Zygosity: ht
Has Mutant Allele: true
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DO Term
DOID:0060878 | hypoparathyroidism-deafness-renal disease syndrome
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Allele
Gata3<em1(flpo)Good> | MGI:7855857
Name: GATA binding protein 3; endonuclease-mediated mutation 1, Lisa Goodrich
Allele Type: Endonuclease-mediated
Attribute String: Recombinase
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Allele
Col1a1<tm17(CAG-Gata3,-luc2)Nki> | MGI:6316336
Name: collagen, type I, alpha 1; targeted mutation 17, The Netherlands Cancer Institute
Allele Type: Targeted
Attribute String: Conditional ready, Inserted expressed sequence, Reporter
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Allele
Col1a1<tm18(CAG-Gata3,-luc2)Nki> | MGI:6316337
Name: collagen, type I, alpha 1; targeted mutation 17, The Netherlands Cancer Institute
Allele Type: Targeted
Attribute String: Conditional ready, Inserted expressed sequence, Reporter
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Allele
Tg(Rr340-Gata3)#Jeng | MGI:7414089
Name: transgene insertion, James Douglas Engel
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Del(2Rr509-Rr508)1Jirna | MGI:7709728
Name: deletion, Chr 2, Hiroshi Nakajima 1
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
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Allele
Del(2Rr509-Rr508)2Jirna | MGI:7709746
Name: deletion, Chr 2, Hiroshi Nakajima 2
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
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GXD Expression
GXD Expression
Probe: MGI:6356544
Assay Type: Immunohistochemistry
Annotation Date: 2019-09-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757722
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:6360666
Age: embryonic day 14.5
Image: 3E
Note: Expression was detected in interneurons. There was some co-expression with Gata3 positive V2b interneurons. Only the Pax6 interneurons settled in the ventral spinal cord coexpressed Gata3, and not the Pax6 interneurons when they migrate out of the ventricular zone.
Specimen Label: 3E
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
Probe: MGI:6356544
Assay Type: Immunohistochemistry
Annotation Date: 2019-09-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757722
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:6360666
Age: embryonic day 14.5
Image: 4C
Note: Expression was detected in interneurons. There was some co-expression with Pax2 positive ventral V0 interneurons and with Gata3 positive V2b interneurons. There were also Pax6 positive interneurons that do not express either Pax2 or Gata3.
Specimen Label: 4C
Detected: true
Specimen Num: 9
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Allele
Gata3<tm1.1Hjf> | MGI:6508674
Name: GATA binding protein 3; targeted mutation 1.1, Hans Joerg Fehling
Allele Type: Targeted
Attribute String: No functional change, Reporter
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Allele
Tg(Rr340-EGFP)#Jeng | MGI:7414090
Name: transgene insertion, James Douglas Engel
Allele Type: Transgenic
Attribute String: Reporter
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Allele
Tg(Rr340-lacZ)#Jeng | MGI:7414091
Name: transgene insertion, James Douglas Engel
Allele Type: Transgenic
Attribute String: Reporter
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Strain
MGI:6475331 | C57BL/6JSmoc-Gata3<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Allele
Tg(Rr338-EGFP)#Jeng | MGI:7413141
Name: transgene insertion, James Douglas Engel
Allele Type: Transgenic
Attribute String: Reporter
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Allele
Tg(Gata3-EGFP)#Jeng | MGI:7413142
Name: transgene insertion, James Douglas Engel
Allele Type: Transgenic
Attribute String: Reporter
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Allele
Tg(Gata3)C4Jeng | MGI:7413192
Name: transgene insertion C4, James Douglas Engel
Allele Type: Transgenic
Attribute String: Conditional ready, Inserted expressed sequence
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Allele
Rr338<em1Jeng> | MGI:7413214
Name: regulatory region 338; endonuclease-mediated mutation 1, James Douglas Engel
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, Modified regulatory region
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Allele
Tg(Gata3-lacZ)260A19Jeng | MGI:7442284
Name: transgene insertion 260A19, James Douglas Engel
Allele Type: Transgenic
Attribute String: Reporter
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Allele
Tg(Gata3-cre)2471Jeng | MGI:7442300
Name: transgene insertion 2471, James Douglas Engel
Allele Type: Transgenic
Attribute String: Recombinase
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Allele
Tg(Gata3-cre)2476Jeng | MGI:7442301
Name: transgene insertion 2476, James Douglas Engel
Allele Type: Transgenic
Attribute String: Recombinase
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Allele
Tg(Gata3*-cre)2481Jeng | MGI:7442302
Name: transgene insertion 2481, James Douglas Engel
Allele Type: Transgenic
Attribute String: Recombinase
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Allele
Tg(Gata3-lacZ)OVEJeng | MGI:7442294
Name: transgene insertion OVE, James Douglas Engel
Allele Type: Transgenic
Attribute String: Reporter
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Allele
Gata3<em1Aben> | MGI:7518200
Name: GATA binding protein 3; endonuclease-mediated mutation 1, Albert Bendelac
Allele Type: Endonuclease-mediated
Attribute String: Reporter
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Publication
1638017 | -
First Author: Orkin SH
Year: 1992
Journal: Blood
Title: GATA-binding transcription factors in hematopoietic cells.
Volume: 80
Issue: 3
Pages: 575-81
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Protein Domain
IPR016374 | TF_GATA-2/3
Type: Family
Description: GATA transcription factors mediate processes of development, differentiation, and gene expression in multiple tissues and cell types. Vertebrate GATA factors have two highly conserved zinc finger motifs and recognise a six-nucleotide motif T/AGATAG/A in target genes. They are separated into two subfamilies: 1) GATA1, GATA2, and GATA3 and 2) GATA4, GATA5, and GATA6. Members of the GATA1/2/3 subfamily are expressed in developing blood cells, where they regulate differentiation-specific gene expression in hematopoiesis []. This entry represents the GATA2 and GATA3.
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Allele
Gata1<tm5(GATA3)Sho> | MGI:2429992
 
Name: GATA binding protein 1; targeted mutation 5, Stuart Orkin
Allele Type: Targeted
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Allele
Tg(CD2-Gata3)1Staka | MGI:3777641
Name: transgene insertion 1, Satoru Takahashi
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(GATA3-EGFP)1Smal | MGI:4838415
Name: transgene insertion 1, Stavros Malas
Allele Type: Transgenic
Attribute String: Reporter
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Strain
MGI:7444935 | B6.Cg-Gata3<tm1.1Hjf>/J
Attribute String: congenic, mutant strain, targeted mutation
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Allele
Tg(Gata3-lacZ)-308Jeng | MGI:7413953
Name: transgene insertion -308, James Douglas Engel
Allele Type: Transgenic
Attribute String: Reporter
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Allele
Tg(Gata3-lacZ)-2052Jeng | MGI:7413954
Name: transgene insertion -2052, James Douglas Engel
Allele Type: Transgenic
Attribute String: Reporter
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Allele
Tg(Gata3-lacZ)-4500Jeng | MGI:7413955
Name: transgene insertion -4500, James Douglas Engel
Allele Type: Transgenic
Attribute String: Reporter
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Allele
Tg(RP23-43G17)7.1Jeng | MGI:7413114
Name: transgene insertion 7.1, James Douglas Engel
Allele Type: Transgenic
Attribute String: Reporter
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Allele
Tg(Gata3-lacZ)B125Jeng | MGI:7413189
Name: transgene insertion B125, James Douglas Engel
Allele Type: Transgenic
Attribute String: Reporter
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Allele
Tg(Gata3-lacZ)C4Jeng | MGI:7413191
Name: transgene insertion C4, James Douglas Engel
Allele Type: Transgenic
Attribute String: Reporter
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Allele
Tg(Gata3-lacZ)B124Jeng | MGI:7413196
Name: transgene insertion B124, James Douglas Engel
Allele Type: Transgenic
Attribute String: Reporter
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Strain
MGI:6353574 | B6;D2-Tg(Gata3*-cre)2481Jeng/MpuRbrc
Attribute String: transgenic, mutant stock
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Strain
MGI:7518201 | C57BL/6J-Gata3<em1Aben>/J
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Genotype
Genotype
Symbol: Rr338/Rr338
Background: Not Specified
Zygosity: hm
Has Mutant Allele: true
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Allele
Foxm1<em1Pra> | MGI:7331325
Name: forkhead box M1; endonuclease-mediated mutation 1, Pradip Raychaudhuri
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
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Allele
Tg(RP23-43G17)delta7.1Jeng | MGI:7413116
Name: transgene insertion delta7.1, James Douglas Engel
Allele Type: Transgenic
Attribute String: Reporter
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Genotype
Genotype
Symbol: Gata1/?
Background: involves: 129S4/SvJae * C57BL/6
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gata1/Gata1<+>
Background: involves: 129S4/SvJae * C57BL/6
Zygosity: ht
Has Mutant Allele: true
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Publication
15659346 | -
First Author: Cantor AB
Year: 2005
Journal: Semin Cell Dev Biol
Title: Coregulation of GATA factors by the Friend of GATA (FOG) family of multitype zinc finger proteins.
Volume: 16
Issue: 1
Pages: 117-28
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Publication
17936744 | -
First Author: Sorrentino RP
Year: 2007
Journal: Dev Biol
Title: The Friend of GATA protein U-shaped functions as a hematopoietic tumor suppressor in Drosophila.
Volume: 311
Issue: 2
Pages: 311-23
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Protein Domain
IPR039746 | FOG
Type: Family
Description: This entry represents the FOG (Friend of GATA) family, whose members are zinc finger cofactors that regulate GATA factor-activated gene transcription. There are two FOG proteins in mammals, FOG1 and FOG2. They are essential cofactors that act via the formation of a heterodimer with transcription factors of the GATA family GATA1, GATA2 and GATA3 []. In mice, FOG1 is expressed predominantly within the hematopoietic system, while FOG2 is expressed outside of blood, mostly in heart, brain, gonads, and liver [].This entry also includes the FOG homologue from fruit flies, U-shaped (Ush), which is expressed in circulating and lymph gland hemocytes, where it plays a critical role in controlling blood cell proliferation and differentiation [].
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Publication
17717199 | J:147530
First Author: Matsuno Y
Year: 2007
Journal: Am J Respir Crit Care Med
Title: Overexpression of GATA-3 protects against the development of hypersensitivity pneumonitis.
Volume: 176
Issue: 10
Pages: 1015-25
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Strain
MGI:3777782 | B6.Cg-Tg(CD2-Gata3)1Staka/StakaRbrc
Attribute String: congenic, transgenic, mutant strain
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HT Experiment
E-GEOD-15872 | Transcription profiling of mouse stomach, pylorus and duodenum tissue from E14.5 and E16.5 embryos
Series Id: GSE15872
Experiment Type: transcription profiling by array
Study Type: Baseline
Source: ArrayExpress
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HT Experiment
GSE214389 | Single cell RNA sequencing analysis using embryonic day 9.5 placenta from control and GATA DKO mice
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
12100886 | J:78226
First Author: Patient RK
Year: 2002
Journal: Curr Opin Genet Dev
Title: The GATA family (vertebrates and invertebrates).
Volume: 12
Issue: 4
Pages: 416-22
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Gata3-cre)2471Jeng/?
Background: involves: 129S4/SvJaeSor * C57BL/6 * DBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Gata3-cre)2476Jeng/?
Background: involves: 129S4/SvJaeSor * C57BL/6 * DBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Gata3*-cre)2481Jeng/?
Background: involves: 129S4/SvJaeSor * C57BL/6 * DBA
Zygosity: cn
Has Mutant Allele: true
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Publication
12049724 | J:113530
First Author: Zhu J
Year: 2002
Journal: Immunity
Title: Growth factor independent-1 induced by IL-4 regulates Th2 cell proliferation.
Volume: 16
Issue: 5
Pages: 733-44
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Publication
19047684 | J:148305
First Author: Qiu LQ
Year: 2009
Journal: Blood
Title: Viperin is required for optimal Th2 responses and T-cell receptor-mediated activation of NF-kappaB and AP-1.
Volume: 113
Issue: 15
Pages: 3520-9
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Publication
25692701 | J:259905
First Author: Lee JY
Year: 2015
Journal: Immunity
Title: The transcription factor KLF2 restrains CD4⁺ T follicular helper cell differentiation.
Volume: 42
Issue: 2
Pages: 252-264
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Publication
39394532 | J:361012
First Author: He K
Year: 2024
Journal: Nat Immunol
Title: Spatial microniches of IL-2 combine with IL-10 to drive lung migratory T(H)2 cells in response to inhaled allergen.
Volume: 25
Issue: 11
Pages: 2124-2139
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Publication
22425249 | J:187334
First Author: Jones-Mason ME
Year: 2012
Journal: Immunity
Title: E protein transcription factors are required for the development of CD4(+) lineage T cells.
Volume: 36
Issue: 3
Pages: 348-61
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Publication
30049704 | J:266046
First Author: Lei AH
Year: 2018
Journal: J Exp Med
Title: ICAM-1 controls development and function of ILC2.
Volume: 215
Issue: 8
Pages: 2157-2174
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Publication
32399548 | J:302511
 
First Author: He K
Year: 2020
Journal: J Exp Med
Title: Blimp-1 is essential for allergen-induced asthma and Th2 cell development in the lung.
Volume: 217
Issue: 7
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Publication
28747424 | J:244473
First Author: Schwartz C
Year: 2017
Journal: J Exp Med
Title: ILC2s regulate adaptive Th2 cell functions via PD-L1 checkpoint control.
Volume: 214
Issue: 9
Pages: 2507-2521
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Publication
15137944 | J:90018
First Author: Amsen D
Year: 2004
Journal: Cell
Title: Instruction of distinct CD4 T helper cell fates by different notch ligands on antigen-presenting cells.
Volume: 117
Issue: 4
Pages: 515-26
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Publication
17114435 | J:140599
First Author: Hosokawa H
Year: 2006
Journal: J Immunol
Title: Regulation of Th2 cell development by Polycomb group gene bmi-1 through the stabilization of GATA3.
Volume: 177
Issue: 11
Pages: 7656-64
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Publication
11520462 | J:71268
First Author: Kimura M
Year: 2001
Journal: Immunity
Title: Regulation of Th2 cell differentiation by mel-18, a mammalian polycomb group gene.
Volume: 15
Issue: 2
Pages: 275-87
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Publication
21814277 | J:174921
First Author: Weber BN
Year: 2011
Journal: Nature
Title: A critical role for TCF-1 in T-lineage specification and differentiation.
Volume: 476
Issue: 7358
Pages: 63-8
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Publication
18390836 | J:138457
First Author: Guo Y
Year: 2008
Journal: Blood
Title: Core binding factors are necessary for natural killer cell development and cooperate with Notch signaling during T-cell specification.
Volume: 112
Issue: 3
Pages: 480-92
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Publication
36798441 | J:333335
First Author: Lin SC
Year: 2023
Journal: iScience
Title: Endothelial-to-osteoblast transition in normal mouse bone development.
Volume: 26
Issue: 2
Pages: 105994
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Publication
21131966 | J:167446
First Author: Tanaka S
Year: 2011
Journal: Nat Immunol
Title: The enhancer HS2 critically regulates GATA-3-mediated Il4 transcription in T(H)2 cells.
Volume: 12
Issue: 1
Pages: 77-85
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Publication
16713978 | J:113362
First Author: Yamashita M
Year: 2006
Journal: Immunity
Title: Crucial role of MLL for the maintenance of memory T helper type 2 cell responses.
Volume: 24
Issue: 5
Pages: 611-22
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Publication
16543408 | J:108963
First Author: Charles MA
Year: 2006
Journal: Mol Endocrinol
Title: Pituitary-specific Gata2 knockout: effects on gonadotrope and thyrotrope function.
Volume: 20
Issue: 6
Pages: 1366-77
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Publication
24238339 | J:208988
First Author: Tumes DJ
Year: 2013
Journal: Immunity
Title: The polycomb protein Ezh2 regulates differentiation and plasticity of CD4(+) T helper type 1 and type 2 cells.
Volume: 39
Issue: 5
Pages: 819-32
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Publication
15699073 | J:96024
First Author: Kimura MY
Year: 2005
Journal: J Exp Med
Title: Regulation of T helper type 2 cell differentiation by murine Schnurri-2.
Volume: 201
Issue: 3
Pages: 397-408
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Publication
36550322 | J:360961
First Author: Szeto ACH
Year: 2023
Journal: Nat Immunol
Title: An αvβ3 integrin checkpoint is critical for efficient T(H)2 cell cytokine polarization and potentiation of antigen-specific immunity.
Volume: 24
Issue: 1
Pages: 123-135
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Publication
37285842 | J:337870
First Author: Ferreira ACF
Year: 2023
Journal: Immunity
Title: Neuroprotective protein ADNP-dependent histone remodeling complex promotes T helper 2 immune cell differentiation.
Volume: 56
Issue: 7
Pages: 1468-1484.e7
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Publication
20808283 | J:165438
First Author: Yang JQ
Year: 2010
Journal: EMBO J
Title: NBR1 is a new PB1 signalling adapter in Th2 differentiation and allergic airway inflammation in vivo.
Volume: 29
Issue: 19
Pages: 3421-33
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Publication
35687692 | J:325970
First Author: Yang H
Year: 2022
Journal: Sci Adv
Title: The risk variant rs11836367 contributes to breast cancer onset and metastasis by attenuating Wnt signaling via regulating NTN4 expression.
Volume: 8
Issue: 23
Pages: eabn3509
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Publication
16874300 | J:119268
First Author: Martin P
Year: 2006
Journal: EMBO J
Title: The signaling adapter p62 is an important mediator of T helper 2 cell function and allergic airway inflammation.
Volume: 25
Issue: 15
Pages: 3524-33
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Publication
31723060 | J:298374
 
First Author: Sun B
Year: 2019
Journal: JCI Insight
Title: Reciprocal regulation of Th2 and Th17 cells by PAD2-mediated citrullination.
Volume: 4
Issue: 22
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Publication
39883789 | J:361524
   
First Author: Sun Y
Year: 2025
Journal: Science
Title: Casz1 is required for both inner hair cell fate stabilization and outer hair cell survival.
Pages: eado4930
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Publication
19564409 | J:152618
First Author: Wang HC
Year: 2009
Journal: Mol Cell Biol
Title: Id1 attenuates Notch signaling and impairs T-cell commitment by elevating Deltex1 expression.
Volume: 29
Issue: 17
Pages: 4640-52
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Publication
30554919 | J:295053
First Author: Jiao X
Year: 2019
Journal: Stem Cell Reports
Title: Dachshund Depletion Disrupts Mammary Gland Development and Diverts the Composition of the Mammary Gland Progenitor Pool.
Volume: 12
Issue: 1
Pages: 135-151
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Publication
26231117 | J:254628
First Author: Califano D
Year: 2015
Journal: Immunity
Title: Transcription Factor Bcl11b Controls Identity and Function of Mature Type 2 Innate Lymphoid Cells.
Volume: 43
Issue: 2
Pages: 354-68
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Publication
29700302 | J:265729
First Author: Lorentsen KJ
Year: 2018
Journal: Nat Commun
Title: Bcl11b is essential for licensing Th2 differentiation during helminth infection and allergic asthma.
Volume: 9
Issue: 1
Pages: 1679
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Publication
24821970 | J:328420
First Author: Kwon SJ
Year: 2014
Journal: J Immunol
Title: KLF13 cooperates with c-Maf to regulate IL-4 expression in CD4+ T cells.
Volume: 192
Issue: 12
Pages: 5703-9
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Publication
20620941 | J:161995
First Author: Lee K
Year: 2010
Journal: Immunity
Title: Mammalian target of rapamycin protein complex 2 regulates differentiation of Th1 and Th2 cell subsets via distinct signaling pathways.
Volume: 32
Issue: 6
Pages: 743-53
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Publication
10894164 | J:111995
First Author: Agarwal S
Year: 2000
Journal: Immunity
Title: Cell-type-restricted binding of the transcription factor NFAT to a distal IL-4 enhancer in vivo.
Volume: 12
Issue: 6
Pages: 643-52
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Publication
19124715 | J:143503
First Author: Quirion MR
Year: 2009
Journal: J Immunol
Title: Cutting edge: Ikaros is a regulator of Th2 cell differentiation.
Volume: 182
Issue: 2
Pages: 741-5
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Publication
28404635 | J:247791
First Author: Cho S
Year: 2017
Journal: J Immunol
Title: A Novel miR-24-TCF1 Axis in Modulating Effector T Cell Responses.
Volume: 198
Issue: 10
Pages: 3919-3926
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Publication
30315197 | J:267739
First Author: Yamamoto T
Year: 2018
Journal: Nat Commun
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