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Search results 1801 to 1900 out of 3238 for Psen1

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Type Details Score
Publication
First Author: Kandalepas PC
Year: 2013
Journal: Acta Neuropathol
Title: The Alzheimer's β-secretase BACE1 localizes to normal presynaptic terminals and to dystrophic presynaptic terminals surrounding amyloid plaques.
Volume: 126
Issue: 3
Pages: 329-52
Publication
First Author: Illouz T
Year: 2024
Journal: Sci Rep
Title: Unbiased analysis of spatial learning strategies in a modified Barnes maze using convolutional neural networks.
Volume: 14
Issue: 1
Pages: 15944
Publication      
First Author: Taha HB
Year: 2024
Journal: Geroscience
Title: Activation of the muscle-to-brain axis ameliorates neurocognitive deficits in an Alzheimer's disease mouse model via enhancing neurotrophic and synaptic signaling.
Publication
First Author: Kim N
Year: 2023
Journal: J Neuroinflammation
Title: Inhibition of microfold cells ameliorates early pathological phenotypes by modulating microglial functions in Alzheimer's disease mouse model.
Volume: 20
Issue: 1
Pages: 282
Publication
First Author: Saeki K
Year: 2024
Journal: Nat Immunol
Title: IRF8 defines the epigenetic landscape in postnatal microglia, thereby directing their transcriptome programs.
Volume: 25
Issue: 10
Pages: 1928-1942
Publication
First Author: Lee J
Year: 2020
Journal: Aging Cell
Title: Inhibition of REV-ERBs stimulates microglial amyloid-beta clearance and reduces amyloid plaque deposition in the 5XFAD mouse model of Alzheimer's disease.
Volume: 19
Issue: 2
Pages: e13078
Publication
First Author: Lee J
Year: 2023
Journal: Nat Commun
Title: ANKS1A regulates LDL receptor-related protein 1 (LRP1)-mediated cerebrovascular clearance in brain endothelial cells.
Volume: 14
Issue: 1
Pages: 8463
Publication
First Author: Wu Y
Year: 2020
Journal: FASEB J
Title: BHBA treatment improves cognitive function by targeting pleiotropic mechanisms in transgenic mouse model of Alzheimer's disease.
Volume: 34
Issue: 1
Pages: 1412-1429
Publication
First Author: Kozyrev N
Year: 2020
Journal: J Neuropathol Exp Neurol
Title: Infiltrating Hematogenous Macrophages Aggregate Around β-Amyloid Plaques in an Age- and Sex-Dependent Manner in a Mouse Model of Alzheimer Disease.
Volume: 79
Issue: 11
Pages: 1147-1162
Publication
First Author: Bhatia HS
Year: 2022
Journal: Cell
Title: Spatial proteomics in three-dimensional intact specimens.
Volume: 185
Issue: 26
Pages: 5040-5058.e19
Publication
First Author: Kolabas ZI
Year: 2023
Journal: Cell
Title: Distinct molecular profiles of skull bone marrow in health and neurological disorders.
Volume: 186
Issue: 17
Pages: 3706-3725.e29
Publication  
First Author: Dukhinova M
Year: 2019
Journal: Neurobiol Aging
Title: Fresh evidence for major brain gangliosides as a target for the treatment of Alzheimer's disease.
Volume: 77
Pages: 128-143
Publication
First Author: Griciuc A
Year: 2019
Journal: Neuron
Title: TREM2 Acts Downstream of CD33 in Modulating Microglial Pathology in Alzheimer's Disease.
Volume: 103
Issue: 5
Pages: 820-835.e7
Publication  
First Author: Gnoth K
Year: 2022
Journal: Biomolecules
Title: Evidence for Enhanced Efficacy of Passive Immunotherapy against Beta-Amyloid in CD33-Negative 5xFAD Mice.
Volume: 12
Issue: 3
Publication
First Author: Petrov AM
Year: 2019
Journal: FASEB J
Title: The key genes, phosphoproteins, processes, and pathways affected by efavirenz-activated CYP46A1 in the amyloid-decreasing paradigm of efavirenz treatment.
Volume: 33
Issue: 8
Pages: 8782-8798
Publication  
First Author: Liu Y
Year: 2024
Journal: J Neurosci
Title: Imbalance in Glucose Metabolism Regulates the Transition of Microglia from Homeostasis to Disease-Associated Microglia Stage 1.
Volume: 44
Issue: 20
Publication
First Author: Stoyanov S
Year: 2021
Journal: Glia
Title: Attenuation of the extracellular matrix restores microglial activity during the early stage of amyloidosis.
Volume: 69
Issue: 1
Pages: 182-200
Publication
First Author: Baik SH
Year: 2016
Journal: Glia
Title: Microglia contributes to plaque growth by cell death due to uptake of amyloid β in the brain of Alzheimer's disease mouse model.
Volume: 64
Issue: 12
Pages: 2274-2290
Publication  
First Author: Liu J
Year: 2023
Journal: eNeuro
Title: Prevention of Alzheimer Pathology by Blocking Neuregulin Signaling on Microglia.
Volume: 10
Issue: 11
Publication  
First Author: Gyoneva S
Year: 2016
Journal: Neuroscience
Title: Altered motility of plaque-associated microglia in a model of Alzheimer's disease.
Volume: 330
Pages: 410-20
Publication
First Author: Zhou T
Year: 2022
Journal: Nat Commun
Title: Microglial debris is cleared by astrocytes via C4b-facilitated phagocytosis and degraded via RUBICON-dependent noncanonical autophagy in mice.
Volume: 13
Issue: 1
Pages: 6233
Publication
First Author: Shukla AK
Year: 2019
Journal: Glia
Title: CD11a expression distinguishes infiltrating myeloid cells from plaque-associated microglia in Alzheimer's disease.
Volume: 67
Issue: 5
Pages: 844-856
Publication
First Author: Le LHD
Year: 2024
Journal: Sci Rep
Title: Partial microglial depletion and repopulation exert subtle but differential effects on amyloid pathology at different disease stages.
Volume: 14
Issue: 1
Pages: 30912
Publication  
First Author: Wendt S
Year: 2022
Journal: Redox Biol
Title: Simultaneous imaging of redox states in dystrophic neurites and microglia at Aβ plaques indicate lysosome accumulation not microglia correlate with increased oxidative stress.
Volume: 56
Pages: 102448
Publication
First Author: Baik SH
Year: 2019
Journal: Cell Metab
Title: A Breakdown in Metabolic Reprogramming Causes Microglia Dysfunction in Alzheimer's Disease.
Volume: 30
Issue: 3
Pages: 493-507.e6
Publication
First Author: Puntambekar SS
Year: 2022
Journal: Mol Neurodegener
Title: CX3CR1 deficiency aggravates amyloid driven neuronal pathology and cognitive decline in Alzheimer's disease.
Volume: 17
Issue: 1
Pages: 47
Publication
First Author: Leroy K
Year: 2012
Journal: Am J Pathol
Title: Lack of tau proteins rescues neuronal cell death and decreases amyloidogenic processing of APP in APP/PS1 mice.
Volume: 181
Issue: 6
Pages: 1928-40
Publication  
First Author: Choi C
Year: 2023
Journal: Life Sci Alliance
Title: DSCR1 deficiency ameliorates the Aβ pathology of Alzheimer's disease by enhancing microglial activity.
Volume: 6
Issue: 2
Publication  
First Author: Barrett T
Year: 2019
Journal: Neuroscience
Title: p35 Hemizygous Deletion in 5xFAD Mice Increases Aβ Plaque Load in Males but Not in Females.
Volume: 417
Pages: 45-56
Publication
First Author: Yao AY
Year: 2023
Journal: J Neurosci
Title: Bace1 Deletion in the Adult Reverses Epileptiform Activity and Sleep-wake Disturbances in AD Mice.
Volume: 43
Issue: 35
Pages: 6197-6211
Publication
First Author: Mishra P
Year: 2023
Journal: Cell Rep
Title: Rescue of Alzheimer's disease phenotype in a mouse model by transplantation of wild-type hematopoietic stem and progenitor cells.
Volume: 42
Issue: 8
Pages: 112956
Strain
Attribute String: congenic, mutant strain, targeted mutation, transgenic
Publication  
First Author: Pilat D
Year: 2024
Journal: Biomolecules
Title: Suppression of MT5-MMP Reveals Early Modulation of Alzheimer's Pathogenic Events in Primary Neuronal Cultures of 5xFAD Mice.
Volume: 14
Issue: 12
Publication
First Author: Baranger K
Year: 2016
Journal: Cell Mol Life Sci
Title: MT5-MMP is a new pro-amyloidogenic proteinase that promotes amyloid pathology and cognitive decline in a transgenic mouse model of Alzheimer's disease.
Volume: 73
Issue: 1
Pages: 217-36
Publication  
First Author: Baranger K
Year: 2016
Journal: Front Mol Neurosci
Title: MT5-MMP Promotes Alzheimer's Pathogenesis in the Frontal Cortex of 5xFAD Mice and APP Trafficking in vitro.
Volume: 9
Pages: 163
Publication  
First Author: Kumar S
Year: 2023
Journal: JCI Insight
Title: Role of the caspase-8/RIPK3 axis in Alzheimer's disease pathogenesis and Aβ-induced NLRP3 inflammasome activation.
Volume: 8
Issue: 3
Publication
First Author: Miller SR
Year: 2024
Journal: Cell Rep
Title: Machine learning reveals prominent spontaneous behavioral changes and treatment efficacy in humanized and transgenic Alzheimer's disease models.
Volume: 43
Issue: 11
Pages: 114870
Publication
First Author: Gowrishankar S
Year: 2017
Journal: J Cell Biol
Title: Impaired JIP3-dependent axonal lysosome transport promotes amyloid plaque pathology.
Volume: 216
Issue: 10
Pages: 3291-3305
Publication
First Author: Paouri E
Year: 2017
Journal: J Neurosci
Title: Peripheral Tumor Necrosis Factor-Alpha (TNF-α) Modulates Amyloid Pathology by Regulating Blood-Derived Immune Cells and Glial Response in the Brain of AD/TNF Transgenic Mice.
Volume: 37
Issue: 20
Pages: 5155-5171
Publication
First Author: Lin PB
Year: 2023
Journal: Alzheimers Dement
Title: INPP5D deficiency attenuates amyloid pathology in a mouse model of Alzheimer's disease.
Volume: 19
Issue: 6
Pages: 2528-2537
Publication  
First Author: Beck SJ
Year: 2016
Journal: Nat Commun
Title: Deregulation of mitochondrial F1FO-ATP synthase via OSCP in Alzheimer's disease.
Volume: 7
Pages: 11483
Publication
First Author: Devi L
Year: 2013
Journal: PLoS One
Title: Deletion of the eIF2α Kinase GCN2 fails to rescue the memory decline associated with Alzheimer's disease.
Volume: 8
Issue: 10
Pages: e77335
Publication  
First Author: Varbanov H
Year: 2023
Journal: Neurobiol Dis
Title: Rescue of synaptic and cognitive functions in polysialic acid-deficient mice and dementia models by short polysialic acid fragments.
Volume: 180
Pages: 106079
Publication  
First Author: Gauba E
Year: 2019
Journal: Neurobiol Dis
Title: Cyclophilin D deficiency attenuates mitochondrial F1Fo ATP synthase dysfunction via OSCP in Alzheimer's disease.
Volume: 121
Pages: 138-147
Publication
First Author: Kim W
Year: 2018
Journal: Mol Neurodegener
Title: BACE1 elevation engendered by GGA3 deletion increases β-amyloid pathology in association with APP elevation and decreased CHL1 processing in 5XFAD mice.
Volume: 13
Issue: 1
Pages: 6
Publication  
First Author: Lomoio S
Year: 2020
Journal: Sci Transl Med
Title: Gga3 deletion and a GGA3 rare variant associated with late onset Alzheimer's disease trigger BACE1 accumulation in axonal swellings.
Volume: 12
Issue: 570
Publication
First Author: Wang Y
Year: 2017
Journal: Mol Neurodegener
Title: Gad67 haploinsufficiency reduces amyloid pathology and rescues olfactory memory deficits in a mouse model of Alzheimer's disease.
Volume: 12
Issue: 1
Pages: 73
Publication
First Author: Durrant CS
Year: 2020
Journal: Cell Death Dis
Title: Beta secretase 1-dependent amyloid precursor protein processing promotes excessive vascular sprouting through NOTCH3 signalling.
Volume: 11
Issue: 2
Pages: 98
Publication
First Author: Li R
Year: 2022
Journal: Aging Cell
Title: Accumulation of systematic TPM1 mediates inflammation and neuronal remodeling by phosphorylating PKA and regulating the FABP5/NF-κB signaling pathway in the retina of aged mice.
Volume: 21
Issue: 3
Pages: e13566
Publication  
First Author: Tataryn NM
Year: 2021
Journal: Neurobiol Aging
Title: Vascular endothelial growth factor associated dissimilar cerebrovascular phenotypes in two different mouse models of Alzheimer's Disease.
Volume: 107
Pages: 96-108
Publication
First Author: Ahn HJ
Year: 2014
Journal: J Exp Med
Title: A novel Aβ-fibrinogen interaction inhibitor rescues altered thrombosis and cognitive decline in Alzheimer's disease mice.
Volume: 211
Issue: 6
Pages: 1049-62
Publication
First Author: Kumar P
Year: 2024
Journal: Nat Commun
Title: Native-state proteomics of Parvalbumin interneurons identifies unique molecular signatures and vulnerabilities to early Alzheimer's pathology.
Volume: 15
Issue: 1
Pages: 2823
Publication
First Author: Park K
Year: 2024
Journal: Curr Biol
Title: Memory encoding and retrieval by retrosplenial parvalbumin interneurons are impaired in Alzheimer's disease model mice.
Volume: 34
Issue: 2
Pages: 434-443.e4
Publication  
First Author: Li H
Year: 2022
Journal: Neurobiol Aging
Title: Loss of SST and PV positive interneurons in the ventral hippocampus results in anxiety-like behavior in 5xFAD mice.
Volume: 117
Pages: 165-178
Publication
First Author: Hur JY
Year: 2020
Journal: Nature
Title: The innate immunity protein IFITM3 modulates γ-secretase in Alzheimer's disease.
Volume: 586
Issue: 7831
Pages: 735-740
Publication
First Author: Ali F
Year: 2019
Journal: J Alzheimers Dis
Title: Parvalbumin-Positive Neuron Loss and Amyloid-β Deposits in the Frontal Cortex of Alzheimer's Disease-Related Mice.
Volume: 72
Issue: 4
Pages: 1323-1339
Publication
First Author: Caccavano A
Year: 2020
Journal: J Neurosci
Title: Inhibitory Parvalbumin Basket Cell Activity is Selectively Reduced during Hippocampal Sharp Wave Ripples in a Mouse Model of Familial Alzheimer's Disease.
Volume: 40
Issue: 26
Pages: 5116-5136
Publication      
First Author: Bouin A
Year: 2024
Journal: Mol Psychiatry
Title: New rabies viral resources for multi-scale neural circuit mapping.
Publication
First Author: Wilson CA
Year: 2020
Journal: Sci Rep
Title: Effects of optogenetic stimulation of basal forebrain parvalbumin neurons on Alzheimer's disease pathology.
Volume: 10
Issue: 1
Pages: 15456
Publication
First Author: Tian J
Year: 2023
Journal: iScience
Title: Low-temperature resin embedding of the whole brain for various precise structures dissection.
Volume: 26
Issue: 5
Pages: 106705
Publication
First Author: Tian J
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: Dissection of the long-range projections of specific neurons at the synaptic level in the whole mouse brain.
Volume: 119
Issue: 40
Pages: e2202536119
Publication  
First Author: Angel A
Year: 2020
Journal: Int J Mol Sci
Title: Caspase-6 Knockout in the 5xFAD Model of Alzheimer's Disease Reveals Favorable Outcome on Memory and Neurological Hallmarks.
Volume: 21
Issue: 3
Publication  
First Author: Herzer S
Year: 2018
Journal: Front Mol Neurosci
Title: Deletion of Specific Sphingolipids in Distinct Neurons Improves Spatial Memory in a Mouse Model of Alzheimer's Disease.
Volume: 11
Pages: 206
Publication
First Author: Burgert T
Year: 2013
Journal: Mol Cell Biol
Title: SORLA-dependent and -independent functions for PACS1 in control of amyloidogenic processes.
Volume: 33
Issue: 21
Pages: 4308-20
Publication
First Author: Walter S
Year: 2019
Journal: Acta Neuropathol
Title: The metalloprotease ADAMTS4 generates N-truncated Aβ4-x species and marks oligodendrocytes as a source of amyloidogenic peptides in Alzheimer's disease.
Volume: 137
Issue: 2
Pages: 239-257
Publication
First Author: Zhang J
Year: 2018
Journal: Mol Neurobiol
Title: Alleviation of Neuropathology by Inhibition of Monoacylglycerol Lipase in APP Transgenic Mice Lacking CB2 Receptors.
Volume: 55
Issue: 6
Pages: 4802-4810
Publication  
First Author: Back MK
Year: 2021
Journal: Int J Mol Sci
Title: Amyloid Beta-Mediated Changes in Synaptic Function and Spine Number of Neocortical Neurons Depend on NMDA Receptors.
Volume: 22
Issue: 12
Publication  
First Author: Tian J
Year: 2019
Journal: Sci Transl Med
Title: Disrupted hippocampal growth hormone secretagogue receptor 1α interaction with dopamine receptor D1 plays a role in Alzheimer's disease.
Volume: 11
Issue: 505
Publication
First Author: Kisler K
Year: 2023
Journal: Mol Neurodegener
Title: Anti-malaria drug artesunate prevents development of amyloid-β pathology in mice by upregulating PICALM at the blood-brain barrier.
Volume: 18
Issue: 1
Pages: 7
Publication
First Author: Gräff J
Year: 2012
Journal: Nature
Title: An epigenetic blockade of cognitive functions in the neurodegenerating brain.
Volume: 483
Issue: 7388
Pages: 222-6
Publication
First Author: Morshed N
Year: 2020
Journal: Mol Syst Biol
Title: Phosphoproteomics identifies microglial Siglec-F inflammatory response during neurodegeneration.
Volume: 16
Issue: 12
Pages: e9819
Publication  
First Author: Estfanous S
Year: 2021
Journal: Front Immunol
Title: Elevated Expression of MiR-17 in Microglia of Alzheimer's Disease Patients Abrogates Autophagy-Mediated Amyloid-β Degradation.
Volume: 12
Pages: 705581
Publication
First Author: Lorenzetto E
Year: 2014
Journal: Brain Struct Funct
Title: Distribution of different isoforms of receptor protein tyrosine phosphatase γ (Ptprg-RPTP γ) in adult mouse brain: upregulation during neuroinflammation.
Volume: 219
Issue: 3
Pages: 875-90
Strain
Attribute String: transgenic, F1 hybrid
Strain
Attribute String: F1 hybrid, transgenic
Strain
Attribute String: transgenic, F1 hybrid
Strain
Attribute String: F1 hybrid, transgenic
Strain
Attribute String: targeted mutation, transgenic, mutant strain, congenic
Strain
Attribute String: F1 hybrid, mutant strain, transgenic
Strain
Attribute String: F1 hybrid, mutant strain, transgenic
Strain
Attribute String: F1 hybrid, transgenic
Strain
Attribute String: F1 hybrid, mutant strain, transgenic
Strain
Attribute String: transgenic, F1 hybrid
Strain
Attribute String: congenic, mutant strain, transgenic
Strain
Attribute String: F1 hybrid, mutant strain, transgenic
Strain
Attribute String: transgenic, mutant strain, F1 hybrid
Strain
Attribute String: transgenic, F1 hybrid
Strain
Attribute String: F1 hybrid, mutant strain, transgenic
Strain
Attribute String: F1 hybrid, transgenic
Strain
Attribute String: transgenic, mutant strain, F1 hybrid
Strain
Attribute String: congenic, mutant strain, targeted mutation, transgenic
Strain
Attribute String: transgenic, F1 hybrid
Strain
Attribute String: F1 hybrid, transgenic
Strain
Attribute String: mutant stock, transgenic
Strain
Attribute String: congenic, mutant strain, transgenic
Strain
Attribute String: congenic, transgenic
Strain
Attribute String: transgenic, F1 hybrid
Strain
Attribute String: F1 hybrid, transgenic
Strain
Attribute String: F1 hybrid, transgenic
Strain
Attribute String: congenic, mutant strain, transgenic