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Search results 1801 to 1899 out of 1899 for Rag2

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Type Details Score
Publication
16166587 | J:126197
First Author: O'Neil J
Year: 2006
Journal: Blood
Title: Activating Notch1 mutations in mouse models of T-ALL.
Volume: 107
Issue: 2
Pages: 781-5
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Publication
29069605 | J:254855
First Author: Hewitt SL
Year: 2017
Journal: Cell Rep
Title: The Conserved ATM Kinase RAG2-S365 Phosphorylation Site Limits Cleavage Events in Individual Cells Independent of Any Repair Defect.
Volume: 21
Issue: 4
Pages: 979-993
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Publication
23315077 | J:193323
First Author: Nobrega C
Year: 2013
Journal: J Immunol
Title: T cells home to the thymus and control infection.
Volume: 190
Issue: 4
Pages: 1646-58
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Publication
34626548 | J:318010
First Author: Wang Y
Year: 2021
Journal: Immunity
Title: Early developing B cells undergo negative selection by central nervous system-specific antigens in the meninges.
Volume: 54
Issue: 12
Pages: 2784-2794.e6
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Publication
19843939 | J:156798
First Author: Stephen TL
Year: 2009
Journal: J Immunol
Title: The activation threshold of CD4+ T cells is defined by TCR/peptide-MHC class II interactions in the thymic medulla.
Volume: 183
Issue: 9
Pages: 5554-62
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Publication
15173589 | J:90847
First Author: Hirota J
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: The LIM-homeodomain protein Lhx2 is required for complete development of mouse olfactory sensory neurons.
Volume: 101
Issue: 23
Pages: 8751-5
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Publication
32687059 | J:313536
   
First Author: Peligero-Cruz C
Year: 2020
Journal: Elife
Title: IL18 signaling promotes homing of mature Tregs into the thymus.
Volume: 9
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Publication
21148799 | J:168782
First Author: Hale JS
Year: 2011
Journal: J Immunol
Title: Bcl-2-interacting mediator of cell death influences autoantigen-driven deletion and TCR revision.
Volume: 186
Issue: 2
Pages: 799-806
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Publication
21098226 | J:168007
First Author: Chougnet CA
Year: 2011
Journal: J Immunol
Title: A major role for Bim in regulatory T cell homeostasis.
Volume: 186
Issue: 1
Pages: 156-63
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Publication
30962294 | J:274901
First Author: de Pooter RF
Year: 2019
Journal: J Immunol
Title: Cutting Edge: Lymphomyeloid-Primed Progenitor Cell Fates Are Controlled by the Transcription Factor Tal1.
Volume: 202
Issue: 10
Pages: 2837-2842
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Publication
28694386 | J:244426
First Author: White AJ
Year: 2017
Journal: J Exp Med
Title: A type 2 cytokine axis for thymus emigration.
Volume: 214
Issue: 8
Pages: 2205-2216
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Publication
26254339 | J:335281
First Author: McCarthy NI
Year: 2015
Journal: J Immunol
Title: Osteoprotegerin-Mediated Homeostasis of Rank+ Thymic Epithelial Cells Does Not Limit Foxp3+ Regulatory T Cell Development.
Volume: 195
Issue: 6
Pages: 2675-82
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Publication
29285761 | J:262956
First Author: Cowan JE
Year: 2018
Journal: Eur J Immunol
Title: Aire controls the recirculation of murine Foxp3+ regulatory T-cells back to the thymus.
Volume: 48
Issue: 5
Pages: 844-854
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Publication
12165571 | J:78601
First Author: Meffre E
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Deletion of immunoglobulin beta in developing B cells leads to cell death.
Volume: 99
Issue: 17
Pages: 11334-9
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Publication
23401586 | J:193683
First Author: Bhaumik S
Year: 2013
Journal: J Immunol
Title: Retinoic acid hypersensitivity promotes peripheral tolerance in recent thymic emigrants.
Volume: 190
Issue: 6
Pages: 2603-13
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Publication
26832402 | J:269847
First Author: Cowan JE
Year: 2016
Journal: Cell Rep
Title: CCR7 Controls Thymus Recirculation, but Not Production and Emigration, of Foxp3(+) T Cells.
Volume: 14
Issue: 5
Pages: 1041-1048
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Publication
31841113 | J:284585
   
First Author: Jimeno R
Year: 2019
Journal: Elife
Title: Tissue-specific shaping of the TCR repertoire and antigen specificity of iNKT cells.
Volume: 8
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Publication
31792212 | J:286307
First Author: Cowan JE
Year: 2019
Journal: Nat Commun
Title: Myc controls a distinct transcriptional program in fetal thymic epithelial cells that determines thymus growth.
Volume: 10
Issue: 1
Pages: 5498
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Genotype
Genotype
Symbol: Cd79b/Cd79b Tg(IghelMD4)4Ccg/? Tg(Rag2-Igb)1Mnz/?
Background: involves: 129S1/Sv * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd79b/Cd79b Tg(BCL2)22Wehi/? Tg(IghelMD4)4Ccg/? Tg(Rag2-Igb)1Mnz/?
Background: involves: 129S1/Sv * C57BL/6 * C57BL/6JWehi * SJL/JWehi
Zygosity: cx
Has Mutant Allele: true
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Publication
10601033 | J:159089
First Author: Kim DR
Year: 1999
Journal: Genes Dev
Title: Mutations of acidic residues in RAG1 define the active site of the V(D)J recombinase.
Volume: 13
Issue: 23
Pages: 3070-80
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Publication
29602774 | J:261494
First Author: Suárez-Fueyo A
Year: 2018
Journal: J Immunol
Title: Downregulation of CD3ζ in NK Cells from Systemic Lupus Erythematosus Patients Confers a Proinflammatory Phenotype.
Volume: 200
Issue: 9
Pages: 3077-3086
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Publication
28687660 | J:251446
First Author: Resende M
Year: 2017
Journal: J Immunol
Title: Innate IFN-γ-Producing Cells Developing in the Absence of IL-2 Receptor Common γ-Chain.
Volume: 199
Issue: 4
Pages: 1429-1439
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Publication
9545251 | J:127088
First Author: Casellas R
Year: 1998
Journal: EMBO J
Title: Ku80 is required for immunoglobulin isotype switching.
Volume: 17
Issue: 8
Pages: 2404-11
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Publication
17273993 | J:117902
First Author: Hager-Theodorides AL
Year: 2007
Journal: Eur J Immunol
Title: Beta-selection: abundance of TCRbeta-/gammadelta- CD44- CD25- (DN4) cells in the foetal thymus.
Volume: 37
Issue: 2
Pages: 487-500
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Publication
29399633 | J:288807
First Author: Zeng H
Year: 2018
Journal: Sci Adv
Title: Discrete roles and bifurcation of PTEN signaling and mTORC1-mediated anabolic metabolism underlie IL-7-driven B lymphopoiesis.
Volume: 4
Issue: 1
Pages: eaar5701
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Publication
18606696 | J:137658
First Author: Miyakoda M
Year: 2008
Journal: J Immunol
Title: Malaria-specific and nonspecific activation of CD8+ T cells during blood stage of Plasmodium berghei infection.
Volume: 181
Issue: 2
Pages: 1420-8
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Publication
24371308 | J:206374
First Author: Dose M
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: β-Catenin induces T-cell transformation by promoting genomic instability.
Volume: 111
Issue: 1
Pages: 391-6
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Publication
17675505 | J:151217
First Author: Nagase H
Year: 2007
Journal: J Immunol
Title: Despite increased CD4+Foxp3+ cells within the infection site, BALB/c IL-4 receptor-deficient mice reveal CD4+Foxp3-negative T cells as a source of IL-10 in Leishmania major susceptibility.
Volume: 179
Issue: 4
Pages: 2435-44
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Publication
24614102 | J:209613
First Author: Lu Y
Year: 2014
Journal: J Clin Invest
Title: CDK4 deficiency promotes genomic instability and enhances Myc-driven lymphomagenesis.
Volume: 124
Issue: 4
Pages: 1672-84
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Publication
17940206 | J:130688
First Author: Kuo YH
Year: 2008
Journal: Blood
Title: Cbfbeta-SMMHC impairs differentiation of common lymphoid progenitors and reveals an essential role for RUNX in early B-cell development.
Volume: 111
Issue: 3
Pages: 1543-51
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Publication
16410834 | J:105447
First Author: Wang J
Year: 2006
Journal: J Clin Invest
Title: Transcription factor T-bet regulates inflammatory arthritis through its function in dendritic cells.
Volume: 116
Issue: 2
Pages: 414-21
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Publication
17785826 | J:152041
First Author: Wakao H
Year: 2007
Journal: J Immunol
Title: A novel mouse model for invariant NKT cell study.
Volume: 179
Issue: 6
Pages: 3888-95
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Publication
17371983 | J:145055
First Author: Tayade C
Year: 2007
Journal: J Immunol
Title: Genetic deletion of placenta growth factor in mice alters uterine NK cells.
Volume: 178
Issue: 7
Pages: 4267-75
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Publication
26558367 | J:281484
 
First Author: Späni C
Year: 2015
Journal: Acta Neuropathol Commun
Title: Reduced β-amyloid pathology in an APP transgenic mouse model of Alzheimer's disease lacking functional B and T cells.
Volume: 3
Pages: 71
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Publication
24415779 | J:209385
First Author: Horowitz JE
Year: 2014
Journal: J Immunol
Title: Noncore RAG1 regions promote Vβ rearrangements and αβ T cell development by overcoming inherent inefficiency of Vβ recombination signal sequences.
Volume: 192
Issue: 4
Pages: 1609-19
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Publication
17918204 | J:126317
First Author: Ferrero I
Year: 2007
Journal: Eur J Immunol
Title: A critical lineage-nonspecific role for pTalpha in mediating allelic and isotypic exclusion in TCRbeta-transgenic mice.
Volume: 37
Issue: 11
Pages: 3220-8
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Publication
14581608 | J:86464
First Author: Dudley DD
Year: 2003
Journal: J Exp Med
Title: Impaired V(D)J recombination and lymphocyte development in core RAG1-expressing mice.
Volume: 198
Issue: 9
Pages: 1439-50
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Publication
22201127 | J:181712
First Author: Schulz D
Year: 2012
Journal: J Exp Med
Title: Gfi1b negatively regulates Rag expression directly and via the repression of FoxO1.
Volume: 209
Issue: 1
Pages: 187-99
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Publication
37331031 | J:338620
 
First Author: Mei X
Year: 2023
Journal: Mol Immunol
Title: Deficiency of Pink1 promotes the differentiation of Th1 cells.
Volume: 160
Pages: 23-31
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Publication
9464529 | J:45540
First Author: Fuller K
Year: 1997
Journal: Mol Immunol
Title: Identification and characterization of the murine Rag1 promoter.
Volume: 34
Issue: 12-13
Pages: 939-54
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Publication
12644467 | J:83592
First Author: Peak MM
Year: 2003
Journal: J Biol Chem
Title: The central domain of core RAG1 preferentially recognizes single-stranded recombination signal sequence heptamer.
Volume: 278
Issue: 20
Pages: 18235-40
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Publication
16354685 | J:104162
First Author: Weinstock DM
Year: 2006
Journal: Mol Cell Biol
Title: Alternative pathways for the repair of RAG-induced DNA breaks.
Volume: 26
Issue: 1
Pages: 131-9
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Publication
11514603 | J:132923
First Author: Yannoutsos N
Year: 2001
Journal: J Exp Med
Title: The role of recombination activating gene (RAG) reinduction in thymocyte development in vivo.
Volume: 194
Issue: 4
Pages: 471-80
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Publication
16982894 | J:139319
First Author: Patra AK
Year: 2006
Journal: J Immunol
Title: PKB rescues calcineurin/NFAT-induced arrest of Rag expression and pre-T cell differentiation.
Volume: 177
Issue: 7
Pages: 4567-76
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Publication
20852131 | J:167398
First Author: Ashworth TD
Year: 2010
Journal: Blood
Title: Deletion-based mechanisms of Notch1 activation in T-ALL: key roles for RAG recombinase and a conserved internal translational start site in Notch1.
Volume: 116
Issue: 25
Pages: 5455-64
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Publication
23325855 | J:200466
First Author: Little AJ
Year: 2013
Journal: Nucleic Acids Res
Title: Cooperative recruitment of HMGB1 during V(D)J recombination through interactions with RAG1 and DNA.
Volume: 41
Issue: 5
Pages: 3289-301
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Publication
24068669 | J:206246
First Author: Timblin GA
Year: 2013
Journal: J Immunol
Title: Ebf1 and c-Myb repress rag transcription downstream of Stat5 during early B cell development.
Volume: 191
Issue: 9
Pages: 4676-87
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Publication
24368847 | J:206376
First Author: Zhang Y
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: An amphioxus RAG1-like DNA fragment encodes a functional central domain of vertebrate core RAG1.
Volume: 111
Issue: 1
Pages: 397-402
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Publication
26153519 | J:226442
First Author: Ochodnicka-Mackovicova K
Year: 2015
Journal: Blood
Title: NF-κB and AKT signaling prevent DNA damage in transformed pre-B cells by suppressing RAG1/2 expression and activity.
Volume: 126
Issue: 11
Pages: 1324-35
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Publication
28630052 | J:243274
First Author: Rodríguez-Hernández G
Year: 2017
Journal: Cancer Res
Title: Infection Exposure Promotes ETV6-RUNX1 Precursor B-cell Leukemia via Impaired H3K4 Demethylases.
Volume: 77
Issue: 16
Pages: 4365-4377
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Publication
27436288 | J:250263
First Author: Maman Y
Year: 2016
Journal: Nucleic Acids Res
Title: RAG1 targeting in the genome is dominated by chromatin interactions mediated by the non-core regions of RAG1 and RAG2.
Volume: 44
Issue: 20
Pages: 9624-9637
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Publication
29554148 | J:259710
First Author: Bakthavatchalu V
Year: 2018
Journal: PLoS One
Title: Cytotoxic Escherichia coli strains encoding colibactin isolated from immunocompromised mice with urosepsis and meningitis.
Volume: 13
Issue: 3
Pages: e0194443
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Publication
30194965 | J:344767
 
First Author: Feng BS
Year: 2018
Journal: Immunol Lett
Title: Bcl2L12 plays a critical role in the development of intestinal allergy.
Volume: 203
Pages: 87-94
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Publication
27559048 | J:318380
First Author: Ochodnicka-Mackovicova K
Year: 2016
Journal: J Immunol
Title: The DNA Damage Response Regulates RAG1/2 Expression in Pre-B Cells through ATM-FOXO1 Signaling.
Volume: 197
Issue: 7
Pages: 2918-29
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Publication
21061436 | J:165842
First Author: Fortner KA
Year: 2010
Journal: Eur J Immunol
Title: Apoptosis regulators Fas and Bim synergistically control T-lymphocyte homeostatic proliferation.
Volume: 40
Issue: 11
Pages: 3043-53
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Publication
27994150 | J:239383
First Author: Shi LZ
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Gfi1-Foxo1 axis controls the fidelity of effector gene expression and developmental maturation of thymocytes.
Volume: 114
Issue: 1
Pages: E67-E74
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Publication
32284593 | J:305906
First Author: Miller CH
Year: 2020
Journal: Nat Immunol
Title: Eomes identifies thymic precursors of self-specific memory-phenotype CD8+ T cells.
Volume: 21
Issue: 5
Pages: 567-577
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Publication
28507025 | J:252345
First Author: Cunningham CA
Year: 2017
Journal: J Immunol
Title: Cutting Edge: Defective Aerobic Glycolysis Defines the Distinct Effector Function in Antigen-Activated CD8+ Recent Thymic Emigrants.
Volume: 198
Issue: 12
Pages: 4575-4580
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Publication
21928285 | J:179509
First Author: Bayer AL
Year: 2011
Journal: Eur J Immunol
Title: Expansion of a restricted residual host T reg-cell repertoire is dependent on IL-2 following experimental autologous hematopoietic stem transplantation.
Volume: 41
Issue: 12
Pages: 3467-78
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Publication
36104343 | J:336688
First Author: Chen C
Year: 2022
Journal: Nat Commun
Title: Cancer co-opts differentiation of B-cell precursors into macrophage-like cells.
Volume: 13
Issue: 1
Pages: 5376
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Publication
33786850 | J:327057
First Author: Thomas R
Year: 2021
Journal: Immunology
Title: Thymic atrophy creates holes in Treg-mediated immuno-regulation via impairment of an antigen-specific clone.
Volume: 163
Issue: 4
Pages: 478-492
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Publication
15752064 | J:133822
First Author: Tze LE
Year: 2005
Journal: PLoS Biol
Title: Basal immunoglobulin signaling actively maintains developmental stage in immature B cells.
Volume: 3
Issue: 3
Pages: e82
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Publication
26703212 | J:236765
First Author: Kasztura M
Year: 2016
Journal: Arch Immunol Ther Exp (Warsz)
Title: Search for the Function of NWC, Third Gene Within RAG Locus: Generation and Characterization of NWC-Deficient Mice.
Volume: 64
Issue: 4
Pages: 311-9
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Publication
23420886 | J:194463
First Author: Toker A
Year: 2013
Journal: J Immunol
Title: Active demethylation of the Foxp3 locus leads to the generation of stable regulatory T cells within the thymus.
Volume: 190
Issue: 7
Pages: 3180-8
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Strain
MGI:5502342 | B6;129P2-Rag1/Rag2<tm1Mnz>/J
Attribute String: mutant stock, targeted mutation
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Protein
Q8BZ47
Organism: Mus musculus/domesticus
Length: 1413  
Fragment?: false
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Protein
Q56A10
Organism: Mus musculus/domesticus
Length: 1511  
Fragment?: false
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Protein
B9EKR3
Organism: Mus musculus/domesticus
Length: 1511  
Fragment?: false
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Protein
B2RWS7
Organism: Mus musculus/domesticus
Length: 1363  
Fragment?: false
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Publication
30651344 | J:272915
First Author: Ballesteros-Arias L
Year: 2019
Journal: J Immunol
Title: T Cell Acute Lymphoblastic Leukemia as a Consequence of Thymus Autonomy.
Volume: 202
Issue: 4
Pages: 1137-1144
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Publication
9705955 | J:110957
First Author: Thévenin C
Year: 1998
Journal: J Exp Med
Title: Early function of Pax5 (BSAP) before the pre-B cell receptor stage of B lymphopoiesis.
Volume: 188
Issue: 4
Pages: 735-44
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Publication
19729201 | J:155245
First Author: van Hamburg JP
Year: 2009
Journal: Mol Immunol
Title: Gene expression profiling in mice with enforced Gata3 expression reveals putative targets of Gata3 in double positive thymocytes.
Volume: 46
Issue: 16
Pages: 3251-60
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Publication
14687938 | J:87913
First Author: Shockett PE
Year: 2004
Journal: Mol Immunol
Title: Partial reconstitution of V(D)J rearrangement and lymphocyte development in RAG-deficient mice expressing inducible, tetracycline-regulated RAG transgenes.
Volume: 40
Issue: 11
Pages: 813-29
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Publication
29724658 | J:278554
First Author: Angarita SAK
Year: 2018
Journal: Mol Genet Metab
Title: Human hepatocyte transplantation corrects the inherited metabolic liver disorder arginase deficiency in mice.
Volume: 124
Issue: 2
Pages: 114-123
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Publication
32061677 | J:287354
 
First Author: Rios-Arce ND
Year: 2020
Journal: Bone
Title: Post-antibiotic gut dysbiosis-induced trabecular bone loss is dependent on lymphocytes.
Volume: 134
Pages: 115269
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Publication
34996836 | J:344034
First Author: Nomura H
Year: 2022
Journal: J Immunol
Title: IgM to IgG Class Switching Is a Necessary Step for Pemphigus Phenotype Induction in Desmoglein 3-Specific B Cell Receptor Knock-in Mouse.
Volume: 208
Issue: 3
Pages: 582-593
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Publication
36180898 | J:330868
First Author: Faridar A
Year: 2022
Journal: Acta Neuropathol Commun
Title: Ex vivo expanded human regulatory T cells modify neuroinflammation in a preclinical model of Alzheimer's disease.
Volume: 10
Issue: 1
Pages: 144
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Publication
18354197 | J:133383
First Author: Schram BR
Year: 2008
Journal: J Immunol
Title: B cell receptor basal signaling regulates antigen-induced Ig light chain rearrangements.
Volume: 180
Issue: 7
Pages: 4728-41
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Publication
36159793 | J:330105
 
First Author: Apert C
Year: 2022
Journal: Front Immunol
Title: IL-2 and IL-15 drive intrathymic development of distinct periphery-seeding CD4+Foxp3+ regulatory T lymphocytes.
Volume: 13
Pages: 965303
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Publication
21844388 | J:179243
First Author: Rafei M
Year: 2011
Journal: J Immunol
Title: Development and function of innate polyclonal TCRalphabeta+ CD8+ thymocytes.
Volume: 187
Issue: 6
Pages: 3133-44
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Publication
30068595 | J:265210
First Author: Cunningham CA
Year: 2018
Journal: J Immunol
Title: Cutting Edge: Glycolytic Metabolism and Mitochondrial Metabolism Are Uncoupled in Antigen-Activated CD8+ Recent Thymic Emigrants.
Volume: 201
Issue: 6
Pages: 1627-1632
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Publication
24706795 | J:208635
First Author: Higdon LE
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Receptor revision in CD4 T cells is influenced by follicular helper T cell formation and germinal-center interactions.
Volume: 111
Issue: 15
Pages: 5652-7
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Publication
28652304 | J:244235
First Author: Golec DP
Year: 2017
Journal: J Exp Med
Title: Thymic progenitors of TCRαβ+ CD8αα intestinal intraepithelial lymphocytes require RasGRP1 for development.
Volume: 214
Issue: 8
Pages: 2421-2435
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Publication
21478405 | J:173090
First Author: Savage AK
Year: 2011
Journal: J Immunol
Title: Promyelocytic leukemia zinc finger turns on the effector T cell program without requirement for agonist TCR signaling.
Volume: 186
Issue: 10
Pages: 5801-6
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Publication
21576386 | J:176831
First Author: Bréart B
Year: 2011
Journal: J Exp Med
Title: Lipid phosphate phosphatase 3 enables efficient thymic egress.
Volume: 208
Issue: 6
Pages: 1267-78
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Publication
24378538 | J:208352
First Author: Smigiel KS
Year: 2014
Journal: J Exp Med
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