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Search results 1801 to 1900 out of 3140 for Sod1

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Type Details Score
Publication  
First Author: Zhao Z
Year: 2006
Journal: BMC Neurosci
Title: A ketogenic diet as a potential novel therapeutic intervention in amyotrophic lateral sclerosis.
Volume: 7
Pages: 29
Publication
First Author: Gu H
Year: 2015
Journal: Toxicol Sci
Title: The miR-322-TRAF3 circuit mediates the pro-apoptotic effect of high glucose on neural stem cells.
Volume: 144
Issue: 1
Pages: 186-96
Publication
First Author: Yu J
Year: 2016
Journal: J Neurochem
Title: High glucose-induced oxidative stress represses sirtuin deacetylase expression and increases histone acetylation leading to neural tube defects.
Volume: 137
Issue: 3
Pages: 371-83
Strain
Attribute String: transgenic, mutant strain, congenic
Allele
Name: transgene insertion 17, Jeffrey L Elliott
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Strain
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
Genotype
Symbol: Tg(SOD1)76Dpr/?
Background: involves: C3H/HeJ * C57BL/6J
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(SOD1)76Dpr/?
Background: B6.Cg-Tg(SOD1)76Dpr
Zygosity: ot
Has Mutant Allele: true
Publication
First Author: Chang Y
Year: 2008
Journal: PLoS One
Title: Messenger RNA oxidation occurs early in disease pathogenesis and promotes motor neuron degeneration in ALS.
Volume: 3
Issue: 8
Pages: e2849
Publication
First Author: Mesci P
Year: 2015
Journal: Brain
Title: System xC- is a mediator of microglial function and its deletion slows symptoms in amyotrophic lateral sclerosis mice.
Volume: 138
Issue: Pt 1
Pages: 53-68
Publication
First Author: Bravo-Hernandez M
Year: 2020
Journal: Nat Med
Title: Spinal subpial delivery of AAV9 enables widespread gene silencing and blocks motoneuron degeneration in ALS.
Volume: 26
Issue: 1
Pages: 118-130
Publication
First Author: Gurney ME
Year: 1998
Journal: Age (Omaha)
Title: Mutant Cu,Zn superoxide dismutase in motor neuron disease.
Volume: 21
Issue: 2
Pages: 85-9
Publication
First Author: Pun S
Year: 2006
Journal: Nat Neurosci
Title: Selective vulnerability and pruning of phasic motoneuron axons in motoneuron disease alleviated by CNTF.
Volume: 9
Issue: 3
Pages: 408-19
Publication
First Author: Filali M
Year: 2011
Journal: Behav Brain Res
Title: Sensorimotor and cognitive functions in a SOD1(G37R) transgenic mouse model of amyotrophic lateral sclerosis.
Volume: 225
Issue: 1
Pages: 215-21
Publication
First Author: Ezzi SA
Year: 2010
Journal: J Neurochem
Title: Neuronal over-expression of chromogranin A accelerates disease onset in a mouse model of ALS.
Volume: 115
Issue: 5
Pages: 1102-11
HT Experiment  
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
Publication  
First Author: Guo Y
Year: 2010
Journal: Brain Res
Title: Ultrastructural diversity of inclusions and aggregations in the lumbar spinal cord of SOD1-G93A transgenic mice.
Volume: 1353
Pages: 234-44
Publication
First Author: Williamson TL
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: Absence of neurofilaments reduces the selective vulnerability of motor neurons and slows disease caused by a familial amyotrophic lateral sclerosis-linked superoxide dismutase 1 mutant.
Volume: 95
Issue: 16
Pages: 9631-6
Publication
First Author: Borchelt DR
Year: 1994
Journal: Proc Natl Acad Sci U S A
Title: Superoxide dismutase 1 with mutations linked to familial amyotrophic lateral sclerosis possesses significant activity.
Volume: 91
Issue: 17
Pages: 8292-6
Publication
First Author: Sago H
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: Ts1Cje, a partial trisomy 16 mouse model for Down syndrome, exhibits learning and behavioral abnormalities.
Volume: 95
Issue: 11
Pages: 6256-61
Publication
First Author: Shukkur EA
Year: 2006
Journal: Hum Mol Genet
Title: Mitochondrial dysfunction and tau hyperphosphorylation in Ts1Cje, a mouse model for Down syndrome.
Volume: 15
Issue: 18
Pages: 2752-62
Publication
First Author: Hensley K
Year: 2002
Journal: J Neurochem
Title: Temporal patterns of cytokine and apoptosis-related gene expression in spinal cords of the G93A-SOD1 mouse model of amyotrophic lateral sclerosis.
Volume: 82
Issue: 2
Pages: 365-74
Publication
First Author: Wu AS
Year: 2003
Journal: J Neurochem
Title: Iron porphyrin treatment extends survival in a transgenic animal model of amyotrophic lateral sclerosis.
Volume: 85
Issue: 1
Pages: 142-50
Publication
First Author: Guo H
Year: 2003
Journal: Hum Mol Genet
Title: Increased expression of the glial glutamate transporter EAAT2 modulates excitotoxicity and delays the onset but not the outcome of ALS in mice.
Volume: 12
Issue: 19
Pages: 2519-32
Publication  
First Author: Jiang MC
Year: 2017
Journal: Neuroscience
Title: Hyperexcitability in synaptic and firing activities of spinal motoneurons in an adult mouse model of amyotrophic lateral sclerosis.
Volume: 362
Pages: 33-46
Publication
First Author: Luo G
Year: 2013
Journal: PLoS One
Title: Defective mitochondrial dynamics is an early event in skeletal muscle of an amyotrophic lateral sclerosis mouse model.
Volume: 8
Issue: 12
Pages: e82112
Publication
First Author: Ohta Y
Year: 2016
Journal: Hum Mol Genet
Title: Sex-dependent effects of chromogranin B P413L allelic variant as disease modifier in amyotrophic lateral sclerosis.
Volume: 25
Issue: 21
Pages: 4771-4786
Allele  
Name: VPS54 GARP complex subunit; wobbler
Allele Type: Spontaneous
Allele
Name: transgene insertion, Jean-Pierre Julien
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
Allele
Name: transgene insertion, Jean-Pierre Julien
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
Publication  
First Author: Dobrowolny G
Year: 2018
Journal: Front Physiol
Title: Metabolic Changes Associated With Muscle Expression of SOD1G93A.
Volume: 9
Pages: 831
Allele
Name: transgene insertion 135, Lawrence SB Goldstein
Allele Type: Transgenic
Attribute String: Humanized sequence, Inducible, Inserted expressed sequence, Reporter
Allele
Name: transgene insertion 677, Lawrence SB Goldstein
Allele Type: Transgenic
Attribute String: Humanized sequence, Inducible, Inserted expressed sequence, Reporter
Publication
First Author: Tanaka K
Year: 2011
Journal: Exp Neurol
Title: Bromocriptine methylate suppresses glial inflammation and moderates disease progression in a mouse model of amyotrophic lateral sclerosis.
Volume: 232
Issue: 1
Pages: 41-52
Publication
First Author: Yamasaki R
Year: 2010
Journal: J Neuroimmunol
Title: Restoration of microglial function by granulocyte-colony stimulating factor in ALS model mice.
Volume: 229
Issue: 1-2
Pages: 51-62
Publication  
First Author: Morisaki Y
Year: 2016
Journal: Sci Rep
Title: Selective Expression of Osteopontin in ALS-resistant Motor Neurons is a Critical Determinant of Late Phase Neurodegeneration Mediated by Matrix Metalloproteinase-9.
Volume: 6
Pages: 27354
Publication
First Author: Veglianese P
Year: 2006
Journal: Mol Cell Neurosci
Title: Activation of the p38MAPK cascade is associated with upregulation of TNF alpha receptors in the spinal motor neurons of mouse models of familial ALS.
Volume: 31
Issue: 2
Pages: 218-31
Publication
First Author: Kiaei M
Year: 2005
Journal: Exp Neurol
Title: Peroxisome proliferator-activated receptor-gamma agonist extends survival in transgenic mouse model of amyotrophic lateral sclerosis.
Volume: 191
Issue: 2
Pages: 331-6
Publication
First Author: Atkin JD
Year: 2005
Journal: Neuromuscul Disord
Title: Properties of slow- and fast-twitch muscle fibres in a mouse model of amyotrophic lateral sclerosis.
Volume: 15
Issue: 5
Pages: 377-88
Publication  
First Author: Medina DX
Year: 2020
Journal: Front Bioeng Biotechnol
Title: Intravenously Administered, Retinoid Activating Nanoparticles Increase Lifespan and Reduce Neurodegeneration in the SOD1(G93A) Mouse Model of ALS.
Volume: 8
Pages: 224
Publication
First Author: Beers DR
Year: 2001
Journal: J Neurochem
Title: Parvalbumin overexpression alters immune-mediated increases in intracellular calcium, and delays disease onset in a transgenic model of familial amyotrophic lateral sclerosis.
Volume: 79
Issue: 3
Pages: 499-509
Publication    
First Author: Lin CY
Year: 2019
Journal: Elife
Title: Extracellular Pgk1 enhances neurite outgrowth of motoneurons through Nogo66/NgR-independent targeting of NogoA.
Volume: 8
Publication
First Author: Watanabe S
Year: 2024
Journal: Sci Rep
Title: Ebselen analogues delay disease onset and its course in fALS by on-target SOD-1 engagement.
Volume: 14
Issue: 1
Pages: 12118
Publication
First Author: Wooley CM
Year: 2005
Journal: Muscle Nerve
Title: Gait analysis detects early changes in transgenic SOD1(G93A) mice.
Volume: 32
Issue: 1
Pages: 43-50
Publication  
First Author: Lee JK
Year: 2015
Journal: Neurobiol Dis
Title: Iron accumulation promotes TACE-mediated TNF-α secretion and neurodegeneration in a mouse model of ALS.
Volume: 80
Pages: 63-9
Publication
First Author: Trieu VN
Year: 2000
Journal: Biochem Biophys Res Commun
Title: A specific inhibitor of janus kinase-3 increases survival in a transgenic mouse model of amyotrophic lateral sclerosis.
Volume: 267
Issue: 1
Pages: 22-5
Publication
First Author: Shimizu M
Year: 2023
Journal: Sci Adv
Title: RGMa collapses the neuronal actin barrier against disease-implicated protein and exacerbates ALS.
Volume: 9
Issue: 47
Pages: eadg3193
Publication
First Author: Tamgüney G
Year: 2008
Journal: J Gen Virol
Title: Genes contributing to prion pathogenesis.
Volume: 89
Issue: Pt 7
Pages: 1777-1788
Publication
First Author: Yamanaka K
Year: 2008
Journal: Nat Neurosci
Title: Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis.
Volume: 11
Issue: 3
Pages: 251-3
Strain
Attribute String: congenic, mutant strain, transgenic
Publication
First Author: Sun S
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Translational profiling identifies a cascade of damage initiated in motor neurons and spreading to glia in mutant SOD1-mediated ALS.
Volume: 112
Issue: 50
Pages: E6993-7002
Genotype
Symbol: Tg(SOD1*G37R)1Dwc/?
Background: involves: C57BL/6
Zygosity: ot
Has Mutant Allele: true
Publication
First Author: Thireau J
Year: 2008
Journal: Free Radic Biol Med
Title: Increased heart rate variability in mice overexpressing the Cu/Zn superoxide dismutase.
Volume: 45
Issue: 4
Pages: 396-403
Publication
First Author: Lu L
Year: 2007
Journal: J Neurosci
Title: Mutant Cu/Zn-superoxide dismutase associated with amyotrophic lateral sclerosis destabilizes vascular endothelial growth factor mRNA and downregulates its expression.
Volume: 27
Issue: 30
Pages: 7929-38
Publication
First Author: Amano K
Year: 2004
Journal: Hum Mol Genet
Title: Dosage-dependent over-expression of genes in the trisomic region of Ts1Cje mouse model for Down syndrome.
Volume: 13
Issue: 13
Pages: 1333-40
Publication
First Author: Tremblay E
Year: 2017
Journal: J Neurosci
Title: Opposite Synaptic Alterations at the Neuromuscular Junction in an ALS Mouse Model: When Motor Units Matter.
Volume: 37
Issue: 37
Pages: 8901-8918
Publication  
First Author: Crippa V
Year: 2013
Journal: Front Cell Neurosci
Title: Differential autophagy power in the spinal cord and muscle of transgenic ALS mice.
Volume: 7
Pages: 234
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Allele
Name: superoxide dismutase 2, mitochondrial; targeted mutation 1, Charles J Epstein
Allele Type: Targeted
Attribute String: Null/knockout
Publication
First Author: Lim MA
Year: 2014
Journal: Hum Mol Genet
Title: Genetically altering organismal metabolism by leptin-deficiency benefits a mouse model of amyotrophic lateral sclerosis.
Volume: 23
Issue: 18
Pages: 4995-5008
Publication
First Author: Chiu IM
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: T lymphocytes potentiate endogenous neuroprotective inflammation in a mouse model of ALS.
Volume: 105
Issue: 46
Pages: 17913-8
Publication
First Author: Kiaei M
Year: 2007
Journal: Exp Neurol
Title: Matrix metalloproteinase-9 regulates TNF-alpha and FasL expression in neuronal, glial cells and its absence extends life in a transgenic mouse model of amyotrophic lateral sclerosis.
Volume: 205
Issue: 1
Pages: 74-81
Publication
First Author: Matus S
Year: 2013
Journal: PLoS One
Title: Functional contribution of the transcription factor ATF4 to the pathogenesis of amyotrophic lateral sclerosis.
Volume: 8
Issue: 7
Pages: e66672
Publication
First Author: Watanabe S
Year: 2007
Journal: Free Radic Biol Med
Title: Increased affinity for copper mediated by cysteine 111 in forms of mutant superoxide dismutase 1 linked to amyotrophic lateral sclerosis.
Volume: 42
Issue: 10
Pages: 1534-42
Publication
First Author: Dobrowolny G
Year: 2005
Journal: J Cell Biol
Title: Muscle expression of a local Igf-1 isoform protects motor neurons in an ALS mouse model.
Volume: 168
Issue: 2
Pages: 193-9
Publication
First Author: Pérez-García MJ
Year: 2012
Journal: Cell Rep
Title: Increasing MuSK activity delays denervation and improves motor function in ALS mice.
Volume: 2
Issue: 3
Pages: 497-502
Publication
First Author: Di Giorgio FP
Year: 2008
Journal: Cell Stem Cell
Title: Human embryonic stem cell-derived motor neurons are sensitive to the toxic effect of glial cells carrying an ALS-causing mutation.
Volume: 3
Issue: 6
Pages: 637-48
Publication
First Author: Kilic E
Year: 2004
Journal: Neuroscience
Title: The superoxide dismutase1 (SOD1) G93A mutation does not promote neuronal injury after focal brain ischemia and optic nerve transection in mice.
Volume: 128
Issue: 2
Pages: 359-64
Publication
First Author: Pesaresi MG
Year: 2011
Journal: Hum Mol Genet
Title: Mitochondrial redox signalling by p66Shc mediates ALS-like disease through Rac1 inactivation.
Volume: 20
Issue: 21
Pages: 4196-208
Publication
First Author: Gallardo G
Year: 2014
Journal: Nat Neurosci
Title: An α2-Na/K ATPase/α-adducin complex in astrocytes triggers non-cell autonomous neurodegeneration.
Volume: 17
Issue: 12
Pages: 1710-9
Publication  
First Author: BÄ…czyk M
Year: 2020
Journal: J Exp Med
Title: Synaptic restoration by cAMP/PKA drives activity-dependent neuroprotection to motoneurons in ALS.
Volume: 217
Issue: 8
Publication
First Author: Beers DR
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Wild-type microglia extend survival in PU.1 knockout mice with familial amyotrophic lateral sclerosis.
Volume: 103
Issue: 43
Pages: 16021-6
Publication
First Author: Wang R
Year: 2011
Journal: Glia
Title: Activation of interferon signaling pathways in spinal cord astrocytes from an ALS mouse model.
Volume: 59
Issue: 6
Pages: 946-58
Publication
First Author: Tummala H
Year: 2005
Journal: J Biol Chem
Title: Inhibition of chaperone activity is a shared property of several Cu,Zn-superoxide dismutase mutants that cause amyotrophic lateral sclerosis.
Volume: 280
Issue: 18
Pages: 17725-31
Publication
First Author: Dupuis L
Year: 2003
Journal: FASEB J
Title: Up-regulation of mitochondrial uncoupling protein 3 reveals an early muscular metabolic defect in amyotrophic lateral sclerosis.
Volume: 17
Issue: 14
Pages: 2091-3
Publication
First Author: Halter B
Year: 2010
Journal: Free Radic Biol Med
Title: Oxidative stress in skeletal muscle stimulates early expression of Rad in a mouse model of amyotrophic lateral sclerosis.
Volume: 48
Issue: 7
Pages: 915-23
Publication
First Author: Morel L
Year: 2013
Journal: J Biol Chem
Title: Neuronal exosomal miRNA-dependent translational regulation of astroglial glutamate transporter GLT1.
Volume: 288
Issue: 10
Pages: 7105-16
Publication  
First Author: Carreras I
Year: 2010
Journal: Brain Res
Title: Moderate exercise delays the motor performance decline in a transgenic model of ALS.
Volume: 1313
Pages: 192-201
Publication
First Author: Sharp PS
Year: 2005
Journal: Neuroscience
Title: The effect of peripheral nerve injury on disease progression in the SOD1(G93A) mouse model of amyotrophic lateral sclerosis.
Volume: 130
Issue: 4
Pages: 897-910
Publication
First Author: Watanabe S
Year: 2018
Journal: J Neurochem
Title: Intracerebroventricular administration of Cystatin C ameliorates disease in SOD1-linked amyotrophic lateral sclerosis mice.
Volume: 145
Issue: 1
Pages: 80-89
Publication  
First Author: Kim J
Year: 2013
Journal: Neurobiol Dis
Title: Autophagy activation and neuroprotection by progesterone in the G93A-SOD1 transgenic mouse model of amyotrophic lateral sclerosis.
Volume: 59
Pages: 80-5
Publication
First Author: Malik R
Year: 2019
Journal: J Biol Chem
Title: The molecular tweezer CLR01 inhibits aberrant superoxide dismutase 1 (SOD1) self-assembly in vitro and in the G93A-SOD1 mouse model of ALS.
Volume: 294
Issue: 10
Pages: 3501-3513
Publication
First Author: Kira Y
Year: 2006
Journal: Brain Res
Title: L-carnitine suppresses the onset of neuromuscular degeneration and increases the life span of mice with familial amyotrophic lateral sclerosis.
Volume: 1070
Issue: 1
Pages: 206-14
Publication  
First Author: Henriques A
Year: 2014
Journal: Front Cell Neurosci
Title: Gene expression changes in spinal motoneurons of the SOD1(G93A) transgenic model for ALS after treatment with G-CSF.
Volume: 8
Pages: 464
Publication
First Author: Rohde G
Year: 2008
Journal: Neuroscience
Title: Neuron-specific overexpression of the co-chaperone Bcl-2-associated athanogene-1 in superoxide dismutase 1(G93A)-transgenic mice.
Volume: 157
Issue: 4
Pages: 844-9
Publication
First Author: Ikeda T
Year: 2023
Journal: Cell Death Discov
Title: Lateral olfactory tract usher substance (LOTUS), an endogenous Nogo receptor antagonist, ameliorates disease progression in amyotrophic lateral sclerosis model mice.
Volume: 9
Issue: 1
Pages: 454
Publication
First Author: Crippa V
Year: 2010
Journal: Hum Mol Genet
Title: The small heat shock protein B8 (HspB8) promotes autophagic removal of misfolded proteins involved in amyotrophic lateral sclerosis (ALS).
Volume: 19
Issue: 17
Pages: 3440-56
Publication
First Author: Marino M
Year: 2015
Journal: Neurobiol Aging
Title: Differences in protein quality control correlate with phenotype variability in 2 mouse models of familial amyotrophic lateral sclerosis.
Volume: 36
Issue: 1
Pages: 492-504
Publication
First Author: Zetterström P
Year: 2011
Journal: J Biol Chem
Title: Proteins that bind to misfolded mutant superoxide dismutase-1 in spinal cords from transgenic amyotrophic lateral sclerosis (ALS) model mice.
Volume: 286
Issue: 23
Pages: 20130-6
Publication
First Author: Luecke IW
Year: 2023
Journal: Gene Ther
Title: Viral vector gene delivery of the novel chaperone protein SRCP1 to modify insoluble protein in in vitro and in vivo models of ALS.
Volume: 30
Issue: 6
Pages: 528-533
Publication
First Author: Rozas P
Year: 2021
Journal: Acta Neuropathol Commun
Title: Protein disulfide isomerase ERp57 protects early muscle denervation in experimental ALS.
Volume: 9
Issue: 1
Pages: 21
Publication
First Author: Alaskarov A
Year: 2022
Journal: Sci Rep
Title: MIF homolog d-dopachrome tautomerase (D-DT/MIF-2) does not inhibit accumulation and toxicity of misfolded SOD1.
Volume: 12
Issue: 1
Pages: 9570
Publication
First Author: Kiaei M
Year: 2006
Journal: J Neurosci
Title: Thalidomide and lenalidomide extend survival in a transgenic mouse model of amyotrophic lateral sclerosis.
Volume: 26
Issue: 9
Pages: 2467-73
Publication
First Author: Venkova K
Year: 2014
Journal: J Neuropathol Exp Neurol
Title: Semaphorin 3A signaling through neuropilin-1 is an early trigger for distal axonopathy in the SOD1G93A mouse model of amyotrophic lateral sclerosis.
Volume: 73
Issue: 7
Pages: 702-13
Publication
First Author: Magrì A
Year: 2023
Journal: Cell Death Dis
Title: ERK1/2-dependent TSPO overactivation associates with the loss of mitophagy and mitochondrial respiration in ALS.
Volume: 14
Issue: 2
Pages: 122
Publication
First Author: Debye B
Year: 2018
Journal: Brain Pathol
Title: Neurodegeneration and NLRP3 inflammasome expression in the anterior thalamus of SOD1(G93A) ALS mice.
Volume: 28
Issue: 1
Pages: 14-27
Publication
First Author: Fujita Y
Year: 2005
Journal: Neuropathology
Title: Golgi apparatus of the motor neurons in patients with amyotrophic lateral sclerosis and in mice models of amyotrophic lateral sclerosis.
Volume: 25
Issue: 4
Pages: 388-94
Publication
First Author: Huang TN
Year: 2024
Journal: Hum Mol Genet
Title: Vcp overexpression and leucine supplementation extend lifespan and ameliorate neuromuscular junction phenotypes of a SOD1G93A-ALS mouse model.
Volume: 33
Issue: 11
Pages: 935-944
Publication
First Author: Lim CKW
Year: 2020
Journal: Mol Ther
Title: Treatment of a Mouse Model of ALS by In Vivo Base Editing.
Volume: 28
Issue: 4
Pages: 1177-1189
Publication
First Author: Schonhoff CM
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: S-nitrosothiol depletion in amyotrophic lateral sclerosis.
Volume: 103
Issue: 7
Pages: 2404-9