| Type |
Details |
Score |
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| First Author: |
Biswas S |
| Year: |
2010 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Hypoxia inducible microRNA 210 attenuates keratinocyte proliferation and impairs closure in a murine model of ischemic wounds. |
| Volume: |
107 |
| Issue: |
15 |
| Pages: |
6976-81 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kaur A |
| Year: |
2015 |
| Journal: |
Diabetes |
| Title: |
Loss of Cyp8b1 improves glucose homeostasis by increasing GLP-1. |
| Volume: |
64 |
| Issue: |
4 |
| Pages: |
1168-79 |
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•
•
•
•
•
|
| Publication |
| First Author: |
Kobiita A |
| Year: |
2020 |
| Journal: |
Cell Rep |
| Title: |
The Diabetes Gene JAZF1 Is Essential for the Homeostatic Control of Ribosome Biogenesis and Function in Metabolic Stress. |
| Volume: |
32 |
| Issue: |
1 |
| Pages: |
107846 |
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•
•
•
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| First Author: |
Ferrández A |
| Year: |
2000 |
| Journal: |
J Biol Chem |
| Title: |
Transcriptional regulation of the divergent paa catabolic operons for phenylacetic acid degradation in Escherichia coli. |
| Volume: |
275 |
| Issue: |
16 |
| Pages: |
12214-22 |
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•
•
•
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| Publication |
| First Author: |
Dalski A |
| Year: |
2001 |
| Journal: |
Cytogenet Cell Genet |
| Title: |
Genomic organization of the human NFAT5 gene: exon-intron structure of the 14-kb transcript and CpG-island analysis of the promoter region. |
| Volume: |
93 |
| Issue: |
3-4 |
| Pages: |
239-41 |
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•
•
•
•
•
|
| Publication |
| First Author: |
Buczkowska A |
| Year: |
2015 |
| Journal: |
J Inherit Metab Dis |
| Title: |
Genetic defects in dolichol metabolism. |
| Volume: |
38 |
| Issue: |
1 |
| Pages: |
157-69 |
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•
•
•
•
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| Publication |
| First Author: |
Locascio A |
| Year: |
2013 |
| Journal: |
Plant Cell Physiol |
| Title: |
Genomic analysis of DELLA protein activity. |
| Volume: |
54 |
| Issue: |
8 |
| Pages: |
1229-37 |
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•
•
•
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| First Author: |
Löffler A |
| Year: |
1993 |
| Journal: |
Eur J Biochem |
| Title: |
Amino acid sequence of an intracellular, phosphate-starvation-induced ribonuclease from cultured tomato (Lycopersicon esculentum) cells. |
| Volume: |
214 |
| Issue: |
3 |
| Pages: |
627-33 |
|
•
•
•
•
•
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| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
81
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| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
83
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| Fragment?: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Söderman A |
| Year: |
2011 |
| Journal: |
Neurosci Lett |
| Title: |
Activation of nicotinic α(7) acetylcholine receptor enhances long term potentation in wild type mice but not in APP(swe)/PS1ΔE9 mice. |
| Volume: |
487 |
| Issue: |
3 |
| Pages: |
325-9 |
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•
•
•
•
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| First Author: |
Easton A |
| Year: |
2003 |
| Journal: |
Genes Brain Behav |
| Title: |
The circadian Clock mutation increases exploratory activity and escape-seeking behavior. |
| Volume: |
2 |
| Issue: |
1 |
| Pages: |
11-9 |
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•
•
•
•
•
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| Publication |
| First Author: |
Miller J |
| Year: |
1981 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Physical linkage of the constant region genes for immunoglobulins lambda I and lambda III. |
| Volume: |
78 |
| Issue: |
6 |
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3829-33 |
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•
•
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| First Author: |
Shimbo A |
| Year: |
2018 |
| Journal: |
Behav Brain Res |
| Title: |
Mice lacking hippocampal left-right asymmetry show non-spatial learning deficits. |
| Volume: |
336 |
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| Pages: |
156-165 |
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•
•
•
•
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| First Author: |
Markotić A |
| Year: |
2002 |
| Journal: |
Clin Exp Immunol |
| Title: |
Ganglioside expression in tissues of mice lacking beta2-microglobulin. |
| Volume: |
128 |
| Issue: |
1 |
| Pages: |
27-35 |
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•
•
•
•
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| Publication |
| First Author: |
Iwamoto A |
| Year: |
2022 |
| Journal: |
J Immunol |
| Title: |
E3 Ubiquitin Ligase Riplet Is Expressed in T Cells and Suppresses T Cell-Mediated Antitumor Immune Responses. |
| Volume: |
208 |
| Issue: |
8 |
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2067-2076 |
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•
•
•
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| Publication |
| First Author: |
Mahuzier A |
| Year: |
2018 |
| Journal: |
Nat Commun |
| Title: |
Ependymal cilia beating induces an actin network to protect centrioles against shear stress. |
| Volume: |
9 |
| Issue: |
1 |
| Pages: |
2279 |
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•
•
•
•
|
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| First Author: |
Rutherford MS |
| Year: |
1993 |
| Journal: |
Genomics |
| Title: |
The gene for murine CTP:phosphocholine cytidylyltransferase (Ctpct) is located on mouse chromosome 16. |
| Volume: |
18 |
| Issue: |
3 |
| Pages: |
698-701 |
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•
•
•
•
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| Publication |
| First Author: |
Scholten D |
| Year: |
2011 |
| Journal: |
Am J Pathol |
| Title: |
Migration of fibrocytes in fibrogenic liver injury. |
| Volume: |
179 |
| Issue: |
1 |
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189-98 |
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•
•
•
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| First Author: |
Vortkamp A |
| Year: |
1996 |
| Journal: |
Science |
| Title: |
Regulation of rate of cartilage differentiation by Indian hedgehog and PTH-related protein. |
| Volume: |
273 |
| Issue: |
5275 |
| Pages: |
613-22 |
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•
•
•
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| First Author: |
Korah N |
| Year: |
2003 |
| Journal: |
Mol Reprod Dev |
| Title: |
Increase in macrophages in the testis of cathepsin a deficient mice suggests an important role for these cells in the interstitial space of this tissue. |
| Volume: |
64 |
| Issue: |
3 |
| Pages: |
302-20 |
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•
•
•
•
•
|
| Publication |
| First Author: |
Yang HM |
| Year: |
2023 |
| Journal: |
Metabolism |
| Title: |
Resistin impairs mitochondrial homeostasis via cyclase-associated protein 1-mediated fission, leading to obesity-induced metabolic diseases. |
| Volume: |
138 |
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| Pages: |
155343 |
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•
•
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| First Author: |
Postat J |
| Year: |
2018 |
| Journal: |
Immunity |
| Title: |
A Metabolism-Based Quorum Sensing Mechanism Contributes to Termination of Inflammatory Responses. |
| Volume: |
49 |
| Issue: |
4 |
| Pages: |
654-665.e5 |
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•
•
•
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| First Author: |
Shen H |
| Year: |
2010 |
| Journal: |
Science |
| Title: |
A critical role for alpha4betadelta GABAA receptors in shaping learning deficits at puberty in mice. |
| Volume: |
327 |
| Issue: |
5972 |
| Pages: |
1515-8 |
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•
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| First Author: |
Csemer A |
| Year: |
2024 |
| Journal: |
Int J Mol Sci |
| Title: |
Pharmacological Activation of Piezo1 Channels Enhances Astrocyte-Neuron Communication via NMDA Receptors in the Murine Neocortex. |
| Volume: |
25 |
| Issue: |
7 |
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•
•
•
•
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| Publication |
| First Author: |
Goncalves A |
| Year: |
2021 |
| Journal: |
Diabetes |
| Title: |
Vascular Expression of Permeability-Resistant Occludin Mutant Preserves Visual Function in Diabetes. |
| Volume: |
70 |
| Issue: |
7 |
| Pages: |
1549-1560 |
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•
•
•
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| First Author: |
Tekinay AB |
| Year: |
2009 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
A role for LYNX2 in anxiety-related behavior. |
| Volume: |
106 |
| Issue: |
11 |
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4477-82 |
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•
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| First Author: |
Sclafani A |
| Year: |
2013 |
| Journal: |
Am J Physiol Regul Integr Comp Physiol |
| Title: |
GPR40 and GPR120 fatty acid sensors are critical for postoral but not oral mediation of fat preferences in the mouse. |
| Volume: |
305 |
| Issue: |
12 |
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R1490-7 |
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Diener N |
| Year: |
2021 |
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Proc Natl Acad Sci U S A |
| Title: |
Posttranslational modifications by ADAM10 shape myeloid antigen-presenting cell homeostasis in the splenic marginal zone. |
| Volume: |
118 |
| Issue: |
38 |
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| First Author: |
Goto A |
| Year: |
2008 |
| Journal: |
Nat Immunol |
| Title: |
Akirins are highly conserved nuclear proteins required for NF-kappaB-dependent gene expression in drosophila and mice. |
| Volume: |
9 |
| Issue: |
1 |
| Pages: |
97-104 |
|
•
•
•
•
•
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| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
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| First Author: |
Yang G |
| Year: |
2002 |
| Journal: |
Stem Cells |
| Title: |
A new assay method for late CFU-S formation and long-term reconstituting activity using a small number of pluripotent hemopoietic stem cells. |
| Volume: |
20 |
| Issue: |
3 |
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241-8 |
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Venkatraman A |
| Year: |
2014 |
| Journal: |
Hum Mol Genet |
| Title: |
The histone deacetylase HDAC3 is essential for Purkinje cell function, potentially complicating the use of HDAC inhibitors in SCA1. |
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23 |
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14 |
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3733-45 |
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Wang H |
| Year: |
2020 |
| Journal: |
Elife |
| Title: |
An AMPK-dependent, non-canonical p53 pathway plays a key role in adipocyte metabolic reprogramming. |
| Volume: |
9 |
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Toh-e A |
| Year: |
1993 |
| Journal: |
Yeast |
| Title: |
Three yeast genes, PIR1, PIR2 and PIR3, containing internal tandem repeats, are related to each other, and PIR1 and PIR2 are required for tolerance to heat shock. |
| Volume: |
9 |
| Issue: |
5 |
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481-94 |
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| First Author: |
Plein A |
| Year: |
2015 |
| Journal: |
J Clin Invest |
| Title: |
Neural crest-derived SEMA3C activates endothelial NRP1 for cardiac outflow tract septation. |
| Volume: |
125 |
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7 |
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Wong E |
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PLoS Pathog |
| Title: |
The Vibrio cholerae colonization factor GbpA possesses a modular structure that governs binding to different host surfaces. |
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Grosmaitre X |
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Proc Natl Acad Sci U S A |
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Odorant responses of olfactory sensory neurons expressing the odorant receptor MOR23: a patch clamp analysis in gene-targeted mice. |
| Volume: |
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Ruddell A |
| Year: |
2003 |
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Am J Pathol |
| Title: |
B lymphocyte-specific c-Myc expression stimulates early and functional expansion of the vasculature and lymphatics during lymphomagenesis. |
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Newbold A |
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Oncogene |
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The role of p21(waf1/cip1) and p27(Kip1) in HDACi-mediated tumor cell death and cell cycle arrest in the Eμ-myc model of B-cell lymphoma. |
| Volume: |
33 |
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Chavez-Reyes A |
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Cancer Res |
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Switching mechanisms of cell death in mdm2- and mdm4-null mice by deletion of p53 downstream targets. |
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2023 |
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Theranostics |
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Kindlin-2 enhances c-Myc translation through association with DDX3X to promote pancreatic ductal adenocarcinoma progression. |
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13 |
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13 |
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| Protein Coding Gene |
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protein_coding_gene |
| Organism: |
mouse, laboratory |
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Shahinian A |
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Science |
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Differential T cell costimulatory requirements in CD28-deficient mice. |
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Papaioannou S |
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Cell Rep |
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Liver sinusoidal endothelial cells orchestrate NK cell recruitment and activation in acute inflammatory liver injury. |
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J Neurosci |
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Loss of mitochondrial fission depletes axonal mitochondria in midbrain dopamine neurons. |
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Genes Dev |
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Autocrine prolactin induced by the Pten-Akt pathway is required for lactation initiation and provides a direct link between the Akt and Stat5 pathways. |
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J Neurobiol |
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Development and topography of the lateral olfactory tract in the mouse: imaging by genetically encoded and injected fluorescent markers. |
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J Biol Chem |
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Proc Natl Acad Sci U S A |
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Cardiovascular homeostasis dependence on MICU2, a regulatory subunit of the mitochondrial calcium uniporter. |
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Nat Biotechnol |
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Chimeric mouse tumor models reveal differences in pathway activation between ERBB family- and KRAS-dependent lung adenocarcinomas. |
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Targeted disruption of the peroxisomal thiolase B gene in mouse: a new model to study disorders related to peroxisomal lipid metabolism. |
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Mus musculus/domesticus |
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Yashchenko A |
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Proc Natl Acad Sci U S A |
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| Pages: |
189-94 |
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•
•
•
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| Publication |
| First Author: |
Mestriner FL |
| Year: |
2007 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Acute-phase protein alpha-1-acid glycoprotein mediates neutrophil migration failure in sepsis by a nitric oxide-dependent mechanism. |
| Volume: |
104 |
| Issue: |
49 |
| Pages: |
19595-600 |
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•
•
•
•
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| Publication |
| First Author: |
Umemura A |
| Year: |
2016 |
| Journal: |
Cancer Cell |
| Title: |
p62, Upregulated during Preneoplasia, Induces Hepatocellular Carcinogenesis by Maintaining Survival of Stressed HCC-Initiating Cells. |
| Volume: |
29 |
| Issue: |
6 |
| Pages: |
935-948 |
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•
•
•
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| Publication |
| First Author: |
Benedykcinska A |
| Year: |
2016 |
| Journal: |
Dis Model Mech |
| Title: |
Generation of brain tumours in mice by Cre-mediated recombination of neural progenitors in situ with the tamoxifen metabolite endoxifen. |
| Volume: |
9 |
| Issue: |
2 |
| Pages: |
211-20 |
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•
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| HT Experiment |
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| Experiment Type: |
RNA-Seq |
| Study Type: |
Baseline |
| Source: |
GEO |
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•
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| Publication |
| First Author: |
Racz B |
| Year: |
2018 |
| Journal: |
J Biol Chem |
| Title: |
A non-retinoid antagonist of retinol-binding protein 4 rescues phenotype in a model of Stargardt disease without inhibiting the visual cycle. |
| Volume: |
293 |
| Issue: |
29 |
| Pages: |
11574-11588 |
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•
•
•
•
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| Publication |
| First Author: |
Rizk A |
| Year: |
2004 |
| Journal: |
Eur J Neurosci |
| Title: |
Anxiety and cognition in histamine H3 receptor-/- mice. |
| Volume: |
19 |
| Issue: |
7 |
| Pages: |
1992-6 |
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•
•
•
•
•
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| Publication |
| First Author: |
Elliott DJ |
| Year: |
2000 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
A mammalian germ cell-specific RNA-binding protein interacts with ubiquitously expressed proteins involved in splice site selection. |
| Volume: |
97 |
| Issue: |
11 |
| Pages: |
5717-22 |
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•
•
•
•
•
|
| Publication |
| First Author: |
Liu S |
| Year: |
2014 |
| Journal: |
Endocrinology |
| Title: |
Disruption of protein-tyrosine phosphatase 1B expression in the pancreas affects β-cell function. |
| Volume: |
155 |
| Issue: |
9 |
| Pages: |
3329-38 |
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•
•
•
•
•
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| Publication |
| First Author: |
Xu J |
| Year: |
2022 |
| Journal: |
Dev Cell |
| Title: |
Excess neuropeptides in lung signal through endothelial cells to impair gas exchange. |
| Volume: |
57 |
| Issue: |
7 |
| Pages: |
839-853.e6 |
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•
•
•
•
•
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| Publication |
| First Author: |
Mattison J |
| Year: |
2010 |
| Journal: |
Cancer Res |
| Title: |
Novel candidate cancer genes identified by a large-scale cross-species comparative oncogenomics approach. |
| Volume: |
70 |
| Issue: |
3 |
| Pages: |
883-95 |
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•
•
•
•
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| Publication |
| First Author: |
Frost A |
| Year: |
2009 |
| Journal: |
Cell |
| Title: |
The BAR domain superfamily: membrane-molding macromolecules. |
| Volume: |
137 |
| Issue: |
2 |
| Pages: |
191-6 |
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•
•
•
•
•
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| Publication |
| First Author: |
Stavniichuk A |
| Year: |
2023 |
| Journal: |
Am J Physiol Renal Physiol |
| Title: |
TRPV4 expression in the renal tubule is necessary for maintaining whole body K(+) homeostasis. |
| Volume: |
324 |
| Issue: |
6 |
| Pages: |
F603-F616 |
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•
•
•
•
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| Publication |
| First Author: |
Xu Y |
| Year: |
2004 |
| Journal: |
J Biol Chem |
| Title: |
Identification and biochemical characterization of two novel collagen binding MSCRAMMs of Bacillus anthracis. |
| Volume: |
279 |
| Issue: |
50 |
| Pages: |
51760-8 |
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•
•
•
•
•
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| Publication |
| First Author: |
Bhusal RP |
| Year: |
2020 |
| Journal: |
Trends Biochem Sci |
| Title: |
Evasins: Tick Salivary Proteins that Inhibit Mammalian Chemokines. |
| Volume: |
45 |
| Issue: |
2 |
| Pages: |
108-122 |
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•
•
•
•
•
|
| Publication |
| First Author: |
Bonvin P |
| Year: |
2014 |
| Journal: |
J Biol Chem |
| Title: |
Identification of the pharmacophore of the CC chemokine-binding proteins Evasin-1 and -4 using phage display. |
| Volume: |
289 |
| Issue: |
46 |
| Pages: |
31846-31855 |
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•
•
•
•
•
|
| Protein Domain |
| Type: |
Domain |
| Description: |
This domain may occur as essentially the full length of a protein, except for an N-terminal sequence and a C-terminal protein-sorting signal such as PEP-CTERM or LPXTG. Most often, the putative surface protein is longer, in which this domain is found N-terminal to repeating stalk domains in bacterial surface proteins. This is one of very few domains for which both anchoring domains occur, and designated choice-of-anchor A domain. The structure model of this domain is highly similar to the Ice_binding adhesive proteins (). However, some of the bacterial species in which this domain can be found, are less likely to be water-based and thus the function seems unlikely to be ice-binding. This domain is found in a Bacillus anthracis protein with the gene name BA_0871 or BASH2_04951, which was described to be collagen binding and to be involved in the bacterial pathogenicity []. BA0871, has five CNA-family protein B-type repeats toward the C terminus and an LPXTG cell wall attachment motif []. |
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•
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•
•
•
|
| Protein Domain |
| Type: |
Family |
| Description: |
Evasins are secreted glycoproteins from ticks, that enhance host blood flow and have anti-inflammatory activity. They bind to chemokines and prevent leukocyte recruitment [, , , ]. Based on the chemokine selectivity they can be divided in two classes: Class A binds CC chemokines and includes Evasin-1 (EVA-1) and Evasin-4, being EVA-1 more selective; Class B Evasins include Evasin-3 which binds and inhibits several CXC chemokines but not CC chemokines.This family represents class A evasins, which contain eight conserved Cys residues that define four intramolecular disulfide bonds. The N- and C-terminal regions are flexible, extend from either side of the core and form a concave surface with the first β-sheet suitable for binding another EVA-1 molecule or to a chemokine. There are two Gly residues strictly conserved. Predicted glycosylation sites were identified on the exterior surface of the structure. Due to its anti-inflammatory activity, these proteins are interesting therapeutic agents [, ]. |
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| Publication |
| First Author: |
Pifferi S |
| Year: |
2006 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Bestrophin-2 is a candidate calcium-activated chloride channel involved in olfactory transduction. |
| Volume: |
103 |
| Issue: |
34 |
| Pages: |
12929-34 |
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•
•
•
•
|
| Publication |
| First Author: |
Fujita A |
| Year: |
2021 |
| Journal: |
J Neurosci |
| Title: |
Neurokinin B-Expressing Neurons of the Central Extended Amygdala Mediate Inhibitory Synaptic Input onto Melanin-Concentrating Hormone Neuron Subpopulations. |
| Volume: |
41 |
| Issue: |
46 |
| Pages: |
9539-9560 |
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•
•
•
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| Publication |
| First Author: |
Irie A |
| Year: |
1998 |
| Journal: |
J Biol Chem |
| Title: |
The molecular basis for the absence of N-glycolylneuraminic acid in humans. |
| Volume: |
273 |
| Issue: |
25 |
| Pages: |
15866-71 |
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•
•
•
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| Publication |
| First Author: |
Sobin A |
| Year: |
1982 |
| Journal: |
Arch Otorhinolaryngol |
| Title: |
Rods of actin filaments in type I hair cells of the Shaker-2 mouse. |
| Volume: |
236 |
| Issue: |
1 |
| Pages: |
1-6 |
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•
•
•
•
•
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| Publication |
| First Author: |
Kalmbach A |
| Year: |
2012 |
| Journal: |
J Neurophysiol |
| Title: |
Selective optogenetic stimulation of cholinergic axons in neocortex. |
| Volume: |
107 |
| Issue: |
7 |
| Pages: |
2008-19 |
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•
•
•
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| Publication |
| First Author: |
Kameyama A |
| Year: |
2021 |
| Journal: |
PLoS One |
| Title: |
Bmi-1 regulates mucin levels and mucin O-glycosylation in the submandibular gland of mice. |
| Volume: |
16 |
| Issue: |
1 |
| Pages: |
e0245607 |
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•
•
•
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| Publication |
| First Author: |
Pattyn A |
| Year: |
2000 |
| Journal: |
Mol Cell Neurosci |
| Title: |
Specification of the central noradrenergic phenotype by the homeobox gene Phox2b. |
| Volume: |
15 |
| Issue: |
3 |
| Pages: |
235-43 |
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•
•
•
•
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| Publication |
| First Author: |
Wakabayashi A |
| Year: |
2022 |
| Journal: |
Life Sci Alliance |
| Title: |
TANK prevents IFN-dependent fatal diffuse alveolar hemorrhage by suppressing DNA-cGAS aggregation. |
| Volume: |
5 |
| Issue: |
2 |
|
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•
•
•
•
•
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| Publication |
| First Author: |
Atkins A |
| Year: |
2020 |
| Journal: |
Elife |
| Title: |
SMC5/6 is required for replication fork stability and faithful chromosome segregation during neurogenesis. |
| Volume: |
9 |
|
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•
•
•
•
•
|
| Publication |
| First Author: |
Hengartner H |
| Year: |
1978 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Assignment of genes for immunoglobulin kappa and heavy chains to chromosomes 6 and 12 in mouse. |
| Volume: |
75 |
| Issue: |
9 |
| Pages: |
4494-8 |
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•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
176
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
104
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
68
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
66
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
128
 |
| Fragment?: |
true |
|
•
•
•
•
•
|