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Search results 18301 to 18400 out of 2418182 for a

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Hits by Strain

Type Details Score
Protein
A0A1B0GS79
Organism: Mus musculus/domesticus
Length: 205  
Fragment?: false
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Publication
12843240 | J:84375
First Author: Martin A
Year: 2003
Journal: J Neurosci
Title: Glial reactivity in ciliary neurotrophic factor-deficient mice after optic nerve lesion.
Volume: 23
Issue: 13
Pages: 5416-24
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Publication
23977192 | J:205836
First Author: Besnard A
Year: 2013
Journal: PLoS One
Title: Recall and reconsolidation of contextual fear memory: differential control by ERK and Zif268 expression dosage.
Volume: 8
Issue: 8
Pages: e72006
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Publication
16266786 | J:105780
First Author: Yuan A
Year: 2006
Journal: Neurosci Lett
Title: Deleting the phosphorylated tail domain of the neurofilament heavy subunit does not alter neurofilament transport rate in vivo.
Volume: 393
Issue: 2-3
Pages: 264-8
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Publication
17664292 | J:125918
First Author: Benarafa C
Year: 2007
Journal: J Exp Med
Title: The neutrophil serine protease inhibitor serpinb1 preserves lung defense functions in Pseudomonas aeruginosa infection.
Volume: 204
Issue: 8
Pages: 1901-9
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Publication
21248149 | J:174751
First Author: Benarafa C
Year: 2011
Journal: J Leukoc Biol
Title: SerpinB1 protects the mature neutrophil reserve in the bone marrow.
Volume: 90
Issue: 1
Pages: 21-9
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Publication
16968134 | J:115952
First Author: Davy A
Year: 2006
Journal: PLoS Biol
Title: Inhibition of gap junction communication at ectopic Eph/ephrin boundaries underlies craniofrontonasal syndrome.
Volume: 4
Issue: 10
Pages: e315
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Publication
29503184 | J:260442
First Author: González-Rueda A
Year: 2018
Journal: Neuron
Title: Activity-Dependent Downscaling of Subthreshold Synaptic Inputs during Slow-Wave-Sleep-like Activity In Vivo.
Volume: 97
Issue: 6
Pages: 1244-1252.e5
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Publication
28912695 | J:247517
 
First Author: Monavarfeshani A
Year: 2017
Journal: Front Integr Neurosci
Title: Region- and Cell-Specific Expression of Transmembrane Collagens in Mouse Brain.
Volume: 11
Pages: 20
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Publication
23922396 | J:200754
First Author: Rubtsova K
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: T-box transcription factor T-bet, a key player in a unique type of B-cell activation essential for effective viral clearance.
Volume: 110
Issue: 34
Pages: E3216-24
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Publication
12925693 | J:85821
First Author: Ristow M
Year: 2003
Journal: J Clin Invest
Title: Frataxin deficiency in pancreatic islets causes diabetes due to loss of beta cell mass.
Volume: 112
Issue: 4
Pages: 527-34
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Publication
32366925 | J:293840
First Author: Rajala A
Year: 2020
Journal: Sci Rep
Title: Metabolic and Non-metabolic Roles of Pyruvate Kinase M2 Isoform in Diabetic Retinopathy.
Volume: 10
Issue: 1
Pages: 7456
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Publication
38878770 | J:360197
First Author: Viengkhou B
Year: 2024
Journal: Immunity
Title: The brain microvasculature is a primary mediator of interferon-α neurotoxicity in human cerebral interferonopathies.
Volume: 57
Issue: 7
Pages: 1696-1709.e10
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Publication
23589855 | J:196134
First Author: Ziętara N
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Critical role for miR-181a/b-1 in agonist selection of invariant natural killer T cells.
Volume: 110
Issue: 18
Pages: 7407-12
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Protein Domain
IPR004412 | GatA
Type: Family
Description: Amidase signature (AS) enzymes are a large group of hydrolytic enzymes that contain a conserved stretch of approximately 130 amino acids known as the AS sequence. They are widespread, being found in both prokaryotes and eukaryotes. AS enzymes catalyse the hydrolysis of amide bonds (CO-NH2), although the family has diverged widely with regard to substrate specificity and function. Nonetheless, these enzymes maintain a core alpha/beta/alpha structure, where the topologies of the N- and C-terminal halves are similar. AS enzymes characteristically have a highly conserved C-terminal region rich in serine and glycine residues, but devoid of aspartic acid and histidine residues, therefore they differ from classical serine hydrolases. These enzymes posses a unique, highly conserved Ser-Ser-Lys catalytic triad used for amide hydrolysis, although the catalytic mechanism for acyl-enzyme intermediate formation can differ between enzymes [].Examples of AS enzymes include:Peptide amidase (Pam) [], which catalyses the hydrolysis of the C-terminal amide bond of peptides.Fatty acid amide hydrolases [], which hydrolyse fatty acid amid substrates (e.g. cannabinoid anandamide and sleep-inducing oleamide), thereby controlling the level and duration of signalling induced by this diverse class of lipid transmitters.Malonamidase E2 [], which catalyses the hydrolysis of malonamate into malonate and ammonia, and which is involved in the transport of fixed nitrogen from bacteroids to plant cells in symbiotic nitrogen metabolism.Subunit A of Glu-tRNA(Gln) amidotransferase [],a heterotrimeric enzyme that catalyses the formation of Gln-tRNA(Gln) by the transamidation of misacylated Glu-tRNA(Gln) via amidolysis of glutamine.In many species, Gln-tRNA ligase is missing. tRNA(Gln) is misacylated with Glu after which a heterotrimeric amidotransferase converts Glu to Gln. This group represents the amidase chain of the heterotrimer, encoded by the gatA gene called glutamyl-tRNA(Gln) amidotransferase, A subunit . This enzyme functions as an alternative to a direct Gln-tRNA synthetase (Gln-tRNA ligase) in mitochondria, chloroplasts, Gram-positive bacteria, cyanobacteria, and the Archaea. The archaea have an Asp-tRNA(Asn) amidotransferase instead of an Asp-tRNA ligase. In the archaea, a paralog of gatB is found, here designated gatB_rel, that is a candidate B subunit of the Asp-tRNA(Asn) amidotransferase. The gatA-encoded subunit may be shared by gatB and gatB_rel.
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Publication
6098446 | J:7734
First Author: Tosi M
Year: 1984
Journal: EMBO J
Title: Multiple non-allelic genes encoding pancreatic alpha-amylase of mouse are expressed in a strain-specific fashion.
Volume: 3
Issue: 12
Pages: 2809-16
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Publication
2436036 | J:20255
First Author: Osborn L
Year: 1987
Journal: Mol Cell Biol
Title: Tissue-specific and insulin-dependent expression of a pancreatic amylase gene in transgenic mice.
Volume: 7
Issue: 1
Pages: 326-34
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Publication
25133605 | J:221003
First Author: Tabata-Imai A
Year: 2014
Journal: PLoS One
Title: Increased sensitivity to inflammatory pain induced by subcutaneous formalin injection in serine racemase knock-out mice.
Volume: 9
Issue: 8
Pages: e105282
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Publication
26755586 | J:229925
First Author: Lee YI
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Neuregulin1 displayed on motor axons regulates terminal Schwann cell-mediated synapse elimination at developing neuromuscular junctions.
Volume: 113
Issue: 4
Pages: E479-87
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Protein Coding Gene
MGI:2445094 | Plekha7
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
36291086 | J:333100
 
First Author: Cibelli A
Year: 2022
Journal: Cells
Title: Activity and Stability of Panx1 Channels in Astrocytes and Neuroblastoma Cells Are Enhanced by Cholesterol Depletion.
Volume: 11
Issue: 20
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Publication
10229797 | J:54920
First Author: Zaballos A
Year: 1999
Journal: J Immunol
Title: Cutting edge: identification of the orphan chemokine receptor GPR-9-6 as CCR9, the receptor for the chemokine TECK.
Volume: 162
Issue: 10
Pages: 5671-5
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Publication
17110437 | J:117146
First Author: Wada-Hiraike O
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Role of estrogen receptor beta in uterine stroma and epithelium: Insights from estrogen receptor beta-/- mice.
Volume: 103
Issue: 48
Pages: 18350-5
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Publication
21853117 | J:176508
First Author: Ribeiro AC
Year: 2011
Journal: PLoS One
Title: Contrasting effects of leptin on food anticipatory and total locomotor activity.
Volume: 6
Issue: 8
Pages: e23364
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Publication
19346403 | J:147972
First Author: Hutcheson DA
Year: 2009
Journal: Genes Dev
Title: Embryonic and fetal limb myogenic cells are derived from developmentally distinct progenitors and have different requirements for beta-catenin.
Volume: 23
Issue: 8
Pages: 997-1013
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Publication
38413581 | J:345973
First Author: Jo-Watanabe A
Year: 2024
Journal: Nat Commun
Title: Bicarbonate signalling via G protein-coupled receptor regulates ischaemia-reperfusion injury.
Volume: 15
Issue: 1
Pages: 1530
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Publication
7894156 | J:22175
First Author: Cheah YC
Year: 1994
Journal: Mamm Genome
Title: New murine polymorphisms detected by random amplified polymorphic DNA (RAPD) PCR and mapped by use of recombinant inbred strains.
Volume: 5
Issue: 12
Pages: 762-7
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Publication
27655900 | J:321061
First Author: Zhao W
Year: 2017
Journal: FASEB J
Title: CCR2 deficiency does not provide sustained improvement of muscular dystrophy in mdx5cv mice.
Volume: 31
Issue: 1
Pages: 35-46
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Publication
22025728 | J:180248
First Author: Hassan H
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Cd8 enhancer E8I and Runx factors regulate CD8α expression in activated CD8+ T cells.
Volume: 108
Issue: 45
Pages: 18330-5
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Publication
15930111 | J:98831
First Author: Kobayashi A
Year: 2005
Journal: Development
Title: Distinct and sequential tissue-specific activities of the LIM-class homeobox gene Lim1 for tubular morphogenesis during kidney development.
Volume: 132
Issue: 12
Pages: 2809-23
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Publication
36278488 | J:331927
 
First Author: Buck A
Year: 2022
Journal: JCI Insight
Title: Spatial metabolomics reveals upregulation of several pyrophosphate-producing pathways in cortical bone of Hyp mice.
Volume: 7
Issue: 20
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Publication
29540796 | J:263705
First Author: Abou-Jaoude A
Year: 2018
Journal: Sci Rep
Title: Loss of the adaptor protein ShcA in endothelial cells protects against monocyte macrophage adhesion, LDL-oxydation, and atherosclerotic lesion formation.
Volume: 8
Issue: 1
Pages: 4501
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Publication
29769330 | J:263012
First Author: Osenberg S
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Activity-dependent aberrations in gene expression and alternative splicing in a mouse model of Rett syndrome.
Volume: 115
Issue: 23
Pages: E5363-E5372
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Publication
24958891 | J:212165
First Author: Castro J
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Functional recovery with recombinant human IGF1 treatment in a mouse model of Rett Syndrome.
Volume: 111
Issue: 27
Pages: 9941-6
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Publication
16954197 | J:113751
First Author: Enquist IB
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Effective cell and gene therapy in a murine model of Gaucher disease.
Volume: 103
Issue: 37
Pages: 13819-24
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Publication
19355789 | J:150498
First Author: Bergthaler A
Year: 2009
Journal: PLoS Biol
Title: Impaired antibody response causes persistence of prototypic T cell-contained virus.
Volume: 7
Issue: 4
Pages: e1000080
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Protein
Q8BHZ0
Organism: Mus musculus/domesticus
Length: 323  
Fragment?: false
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Protein
P06151
Organism: Mus musculus/domesticus
Length: 332  
Fragment?: false
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Publication
1279100 | -
 
First Author: Portela A
Year: 1992
Journal: J Gen Virol
Title: Identification of viral structural polypeptides of Thogoto virus (a tick-borne orthomyxo-like virus) and functions associated with the glycoprotein.
Volume: 73 ( Pt 11)
Pages: 2823-30
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Publication
21708943 | -
First Author: Peng A
Year: 2011
Journal: J Biol Chem
Title: Greatwall and Polo-like kinase 1 coordinate to promote checkpoint recovery.
Volume: 286
Issue: 33
Pages: 28996-9004
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Publication
16289965 | -
First Author: Yamashita A
Year: 2005
Journal: Biochim Biophys Acta
Title: The role of SMG-1 in nonsense-mediated mRNA decay.
Volume: 1754
Issue: 1-2
Pages: 305-15
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Publication
29306014 | -
 
First Author: Frömberg A
Year: 2018
Journal: Cancer Lett
Title: The Special AT-rich Sequence Binding Protein 1 (SATB1) and its role in solid tumors.
Volume: 417
Pages: 96-111
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Publication
24370450 | J:206883
First Author: Murashima A
Year: 2014
Journal: Dev Biol
Title: Midline-derived Shh regulates mesonephric tubule formation through the paraxial mesoderm.
Volume: 386
Issue: 1
Pages: 216-26
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Publication
27459053 | J:233597
First Author: Sánchez-Danés A
Year: 2016
Journal: Nature
Title: Defining the clonal dynamics leading to mouse skin tumour initiation.
Volume: 536
Issue: 7616
Pages: 298-303
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Publication
32916123 | J:310477
First Author: Julien A
Year: 2020
Journal: Stem Cell Reports
Title: FGFR3 in Periosteal Cells Drives Cartilage-to-Bone Transformation in Bone Repair.
Volume: 15
Issue: 4
Pages: 955-967
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Publication
21818378 | J:220936
First Author: Ghosh A
Year: 2011
Journal: PLoS One
Title: Targeted ablation of oligodendrocytes triggers axonal damage.
Volume: 6
Issue: 7
Pages: e22735
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Publication
19406122 | J:304573
First Author: Cambier L
Year: 2009
Journal: FEBS Lett
Title: Fem1a is a mitochondrial protein up-regulated upon ischemia-reperfusion injury.
Volume: 583
Issue: 10
Pages: 1625-30
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Publication
12175489 | J:76826
First Author: Zuniga A
Year: 2002
Journal: Mech Dev
Title: Mouse Twist is required for fibroblast growth factor-mediated epithelial-mesenchymal signalling and cell survival during limb morphogenesis.
Volume: 114
Issue: 1-2
Pages: 51-9
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Publication
7706223 | -
First Author: Hosaka K
Year: 1994
Journal: J Biochem
Title: Cloning and sequence of the SCS3 gene which is required for inositol prototrophy in Saccharomyces cerevisiae.
Volume: 116
Issue: 6
Pages: 1317-21
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Publication
29417057 | -
First Author: Hayes M
Year: 2017
Journal: Microb Cell
Title: Fat storage-inducing transmembrane (FIT or FITM) proteins are related to lipid phosphatase/phosphotransferase enzymes.
Volume: 5
Issue: 2
Pages: 88-103
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Protein Domain
IPR046398 | YFT2
Type: Family
Description: This family represents a group of fungal proteins which belongs to the Fat storage-inducing transmembrane protein family (FITM), including acyl-coenzyme A diphosphatase YFT2 from Saccharomyces cerevisiae, the yeast orthologue of human FIT2 []. This protein is required for ER membrane biosynthesis in response to ER stress, for maintaining ER structure and for lipid droplets (LDs) biogenesis []. YFT2 may support directional budding of nascent LDs from the ER into the cytosol by reducing DAG levels at sites of LD formation [, ].
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Protein Domain
IPR046400 | SCS3
Type: Family
Description: This entry represents Acyl-coenzyme A diphosphatase SCS3 from fungi, a member of the fat storage-inducing transmembrane protein family (FITM) and an orthologue of human FIT2. This protein is required for maintaining ER structure and for lipid droplets (LDs) biogenesis [, , ]. SCS3 may support directional budding of nascent LDs from the ER into the cytosol by reducing DAG levels at sites of LD formation [, ]and it is involved in phospholipid biosynthesis [, , ].
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Protein Domain
IPR003473 | NadA
Type: Family
Description: Quinolinate synthetase catalyses the second step of the de novobiosynthetic pathway of pyridine nucleotide formation. In particular, quinolinate synthetase is involved in the condensation of dihydroxyacetone phosphate and iminoaspartate to form quinolinic acid []. This synthesis requires two enzymes, an FAD-containing "B protein"and an "A protein". B protein converts L-aspartate to iminoaspartate. The A protein, NadA, converts iminoaspartate to quinolate. NadA harbours a [4Fe-4S]cluster [].
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Publication
16636291 | J:109590
First Author: Sakaguchi M
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: A carbohydrate-binding protein, Galectin-1, promotes proliferation of adult neural stem cells.
Volume: 103
Issue: 18
Pages: 7112-7
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Publication
31269437 | J:281871
First Author: Fu Z
Year: 2019
Journal: Cell Rep
Title: Requirement of Mitochondrial Transcription Factor A in Tissue-Resident Regulatory T Cell Maintenance and Function.
Volume: 28
Issue: 1
Pages: 159-171.e4
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Publication
29907856 | J:262620
First Author: Ali A
Year: 2018
Journal: Sci Rep
Title: Deletion of DDB1- and CUL4- associated factor-17 (Dcaf17) gene causes spermatogenesis defects and male infertility in mice.
Volume: 8
Issue: 1
Pages: 9202
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Publication
23160194 | J:193973
First Author: Jones K
Year: 2012
Journal: J Clin Invest
Title: GSK3β mediates muscle pathology in myotonic dystrophy.
Volume: 122
Issue: 12
Pages: 4461-72
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Publication
38651641 | J:338698
   
First Author: Jarysta A
Year: 2024
Journal: Elife
Title: Inhibitory G proteins play multiple roles to polarize sensory hair cell morphogenesis.
Volume: 12
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Publication
31231191 | J:278351
 
First Author: Harris A
Year: 2019
Journal: Front Cell Neurosci
Title: Onecut Factors and Pou2f2 Regulate the Distribution of V2 Interneurons in the Mouse Developing Spinal Cord.
Volume: 13
Pages: 184
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Publication
29116649 | J:305034
First Author: Hermann A
Year: 2018
Journal: Hepatology
Title: WW and C2 domain-containing proteins regulate hepatic cell differentiation and tumorigenesis through the hippo signaling pathway.
Volume: 67
Issue: 4
Pages: 1546-1559
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Publication
27889108 | J:259745
First Author: Skrzypczynska KM
Year: 2016
Journal: Immunity
Title: Positive Regulation of Lyn Kinase by CD148 Is Required for B Cell Receptor Signaling in B1 but Not B2 B Cells.
Volume: 45
Issue: 6
Pages: 1232-1244
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Publication
38902237 | J:350093
First Author: Martinez S
Year: 2024
Journal: Nat Commun
Title: In vivo CRISPR screens reveal SCAF1 and USP15 as drivers of pancreatic cancer.
Volume: 15
Issue: 1
Pages: 5266
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Publication
21098489 | J:168491
First Author: Wei X
Year: 2011
Journal: J Biol Chem
Title: De novo lipogenesis maintains vascular homeostasis through endothelial nitric-oxide synthase (eNOS) palmitoylation.
Volume: 286
Issue: 4
Pages: 2933-45
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Publication
18355449 | J:134154
First Author: Galichet A
Year: 2008
Journal: Biochem Biophys Res Commun
Title: Calcium-regulated intramembrane proteolysis of the RAGE receptor.
Volume: 370
Issue: 1
Pages: 1-5
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Publication
17611414 | J:158490
First Author: Inoue A
Year: 2007
Journal: Cell Cycle
Title: Loss of ChlR1 helicase in mouse causes lethality due to the accumulation of aneuploid cells generated by cohesion defects and placental malformation.
Volume: 6
Issue: 13
Pages: 1646-54
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Publication
- | J:12535
 
First Author: Bishop CE
Year: 1991
Journal: Cytogenet Cell Genet
Title: Mapping the mouse Sxr region in yeast artificial chromosomes: physical linkage of Zfy-2, Zfy-1, Sry, Hya, Spy and a new Y linked gene Sby.
Volume: 58
Pages: 2093 (Abstr.)
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Publication
9252230 | J:42550
First Author: Resibois A
Year: 1997
Journal: Neuroscience
Title: Abnormalities in the cerebellum and brainstem in homozygous lurcher mice.
Volume: 80
Issue: 1
Pages: 175-90
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Publication
38368491 | J:346666
First Author: Nasri A
Year: 2024
Journal: Sci Rep
Title: Suppressive action of nesfatin-1 and nesfatin-1-like peptide on cortisol synthesis in human adrenal cortex cells.
Volume: 14
Issue: 1
Pages: 3985
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Publication
20376364 | J:160175
First Author: Odgren PR
Year: 2010
Journal: PLoS One
Title: Disheveled hair and ear (Dhe), a spontaneous mouse Lmna mutation modeling human laminopathies.
Volume: 5
Issue: 4
Pages: e9959
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Publication
38974964 | J:351467
First Author: Aguilar C
Year: 2024
Journal: iScience
Title: Pleiotropic brain function of whirlin identified by a novel mutation.
Volume: 27
Issue: 7
Pages: 110170
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Publication
20980460 | J:170152
First Author: Mellado-Gil J
Year: 2011
Journal: Diabetes
Title: Disruption of hepatocyte growth factor/c-Met signaling enhances pancreatic beta-cell death and accelerates the onset of diabetes.
Volume: 60
Issue: 2
Pages: 525-36
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Publication
18417707 | J:134542
First Author: Murdoch B
Year: 2008
Journal: J Neurosci
Title: A novel embryonic nestin-expressing radial glia-like progenitor gives rise to zonally restricted olfactory and vomeronasal neurons.
Volume: 28
Issue: 16
Pages: 4271-82
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Publication
16541104 | -
First Author: Itzen A
Year: 2006
Journal: EMBO J
Title: Nucleotide exchange via local protein unfolding--structure of Rab8 in complex with MSS4.
Volume: 25
Issue: 7
Pages: 1445-55
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Publication
30755303 | -
First Author: Raasakka A
Year: 2019
Journal: Biochem Biophys Res Commun
Title: Ionic strength and calcium regulate membrane interactions of myelin basic protein and the cytoplasmic domain of myelin protein zero.
Volume: 511
Issue: 1
Pages: 7-12
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Publication
22247134 | -
First Author: Romano A
Year: 2012
Journal: Appl Environ Microbiol
Title: Evidence of two functionally distinct ornithine decarboxylation systems in lactic acid bacteria.
Volume: 78
Issue: 6
Pages: 1953-61
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Publication
14563862 | -
First Author: Steinhuber A
Year: 2003
Journal: J Bacteriol
Title: Molecular architecture of the regulatory Locus sae of Staphylococcus aureus and its impact on expression of virulence factors.
Volume: 185
Issue: 21
Pages: 6278-86
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Publication
27035626 | J:257565
First Author: Dejda A
Year: 2016
Journal: Invest Ophthalmol Vis Sci
Title: Neuropilin-1-Expressing Microglia Are Associated With Nascent Retinal Vasculature Yet Dispensable for Developmental Angiogenesis.
Volume: 57
Issue: 4
Pages: 1530-6
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Publication
26586792 | J:230584
First Author: Singh A
Year: 2016
Journal: Carcinogenesis
Title: Genetic deletion of TNFα inhibits ultraviolet radiation-induced development of cutaneous squamous cell carcinomas in PKCε transgenic mice via inhibition of cell survival signals.
Volume: 37
Issue: 1
Pages: 72-80
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Publication
23392676 | J:269538
First Author: Gómez-Nicola D
Year: 2013
Journal: J Neurosci
Title: Regulation of microglial proliferation during chronic neurodegeneration.
Volume: 33
Issue: 6
Pages: 2481-93
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Publication
11017072 | J:65025
First Author: Inoue K
Year: 2000
Journal: Nat Genet
Title: Generation of mice with mitochondrial dysfunction by introducing mouse mtDNA carrying a deletion into zygotes.
Volume: 26
Issue: 2
Pages: 176-81
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Publication
22986780 | J:210074
First Author: Capsoni S
Year: 2013
Journal: J Alzheimers Dis
Title: SorLA deficiency dissects amyloid pathology from tau and cholinergic neurodegeneration in a mouse model of Alzheimer's disease.
Volume: 33
Issue: 2
Pages: 357-71
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Publication
8288530 | -
First Author: Kaufmann A
Year: 1994
Journal: J Bacteriol
Title: New outer membrane-associated protease of Escherichia coli K-12.
Volume: 176
Issue: 2
Pages: 359-67
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Publication
1482271 | -
First Author: Jacobi A
Year: 1992
Journal: Arch Microbiol
Title: The hyp operon gene products are required for the maturation of catalytically active hydrogenase isoenzymes in Escherichia coli.
Volume: 158
Issue: 6
Pages: 444-51
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Publication
21459328 | J:172243
First Author: Porat S
Year: 2011
Journal: Cell Metab
Title: Control of pancreatic β cell regeneration by glucose metabolism.
Volume: 13
Issue: 4
Pages: 440-449
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Publication
21659959 | J:222356
First Author: Sabbagha NG
Year: 2011
Journal: Pediatr Res
Title: Alternative splicing in Acad8 resulting a mitochondrial defect and progressive hepatic steatosis in mice.
Volume: 70
Issue: 1
Pages: 31-6
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Publication
8196040 | -
First Author: Kadziola A
Year: 1994
Journal: J Mol Biol
Title: Crystal and molecular structure of barley alpha-amylase.
Volume: 239
Issue: 1
Pages: 104-21
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Publication
38114516 | J:344378
First Author: Toth A
Year: 2023
Journal: Nat Commun
Title: Alveolar epithelial progenitor cells require Nkx2-1 to maintain progenitor-specific epigenomic state during lung homeostasis and regeneration.
Volume: 14
Issue: 1
Pages: 8452
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Publication
18268153 | J:148451
First Author: Fougerat A
Year: 2008
Journal: Circulation
Title: Genetic and pharmacological targeting of phosphoinositide 3-kinase-gamma reduces atherosclerosis and favors plaque stability by modulating inflammatory processes.
Volume: 117
Issue: 10
Pages: 1310-7
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Publication
23674686 | J:197422
First Author: Guerreiro I
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Role of a polymorphism in a Hox/Pax-responsive enhancer in the evolution of the vertebrate spine.
Volume: 110
Issue: 26
Pages: 10682-6
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Publication
18829961 | J:196092
First Author: Haeckel A
Year: 2008
Journal: J Neurosci
Title: The actin-binding protein Abp1 controls dendritic spine morphology and is important for spine head and synapse formation.
Volume: 28
Issue: 40
Pages: 10031-44
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Publication
20356833 | J:164560
First Author: Lou H
Year: 2010
Journal: J Biol Chem
Title: Serine 129 phosphorylation reduces the ability of alpha-synuclein to regulate tyrosine hydroxylase and protein phosphatase 2A in vitro and in vivo.
Volume: 285
Issue: 23
Pages: 17648-61
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Publication
20005824 | J:155739
First Author: Schaefer A
Year: 2009
Journal: Neuron
Title: Control of cognition and adaptive behavior by the GLP/G9a epigenetic suppressor complex.
Volume: 64
Issue: 5
Pages: 678-91
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Publication
11481482 | J:70671
First Author: Horie K
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: Efficient chromosomal transposition of a Tc1/mariner- like transposon Sleeping Beauty in mice.
Volume: 98
Issue: 16
Pages: 9191-6
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Protein Domain
IPR030611 | AURKA
Type: Domain
Description: Aurora kinase A (AURKA, also known as Aurora 2) is a mitotic serine/threonine kinase that contributes to the regulation of cell cycle progression. It associates with the centrosome and the spindle microtubules during mitosis and plays a critical role in regulating centrosome maturation and separation and bipolar spindle assembly [, ]. It also plays an important role in the spindle checkpoint regulation []. Aurora A promotes mitotic entry by controlling activation of Cyclin-B/Cdk-1. It regulates the progression of mitosis by phosphorylation of multiple substrates, such as Polo-like kinase-1, ajuba, enhancer of filamentation 1, BORA, TPX2, PLK-1, astrin, growth arrest and DNA damage-inducible 45alpha, transforming acidic coiled-coil containing protein 3 (TACC3) and centrosomin []. During mitotic exit, AURKA is targeted for degradation through its interaction with the multi-subunit E3-ubiquitin ligase anaphase promoting complex/cyclosome (APC/C) [].The Aurora kinases are highly conserved serine/threonine kinases that regulate chromosomal alignment and segregation during mitosis and meiosis. Three mammalian Aurora kinases, Aurora A, B and C, have been identified. They all contain a protein kinase domain and a destruction box (D-box) recognised by the multi-subunit E3-ubiquitin ligase anaphase promoting complex/cyclosome (APC/C), which mediates their proteasomal degradation. However, their N-terminal domain share little sequence identity and confer unique protein-protein interaction abilities among the Aurora kinases []. They are differentially expressed at high levels in rapidly dividing tissues such as hematopoietic cells (A and B) andgerm cells (C only). Their expression is low or absent in most adult tissues due to their lower rates of proliferation [].
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Protein Domain
IPR024972 | HdeA
Type: Family
Description: HNS (histone-like nucleoid structuring)-dependent expression A (HdeA) protein is a stress response protein found in highly acid resistant bacteria such as Shigella flexneri and Escherichia coli, but which is lacking in mildly acid tolerant bacteria such as Salmonella []. HdeA is one of the most abundant proteins found in the periplasmic space of E. coli, where it is one of a network of proteins that confer an acid resistance phenotype essential for the pathogenesis of enteric bacteria []. HdeA is thought to act as a chaperone, functioning to prevent the aggregation of periplasmic proteins denatured under acidic conditions. The HNS protein, a chromatin-associated protein that influences the gene expression of several environmentally-induced target genes, represses the expression of HdeA. HdeB, which is encoded within the same operon, may form heterodimers with HdeA. HdeA is a single domain α-helical []protein with an overall fold that is similar to the fold of the N-terminal subdomain of the GluRS anticodon-binding domain. This entry represents acid stress chaperone HdeA.
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Protein Domain
IPR036831 | HdeA_sf
Type: Homologous_superfamily
Description: HNS (histone-like nucleoid structuring)-dependent expression A (HdeA) protein is a stress response protein found in highly acid resistant bacteria such as Shigella flexneri and Escherichia coli, but which is lacking in mildly acid tolerant bacteria such as Salmonella []. HdeA is one of the most abundant proteins found in the periplasmic space of E. coli, where it is one of a network of proteins that confer an acid resistance phenotypeessential for the pathogenesis of enteric bacteria []. HdeA is thought to act as a chaperone, functioning to prevent the aggregation of periplasmic proteins denatured under acidic conditions. The HNS protein, a chromatin-associated protein that influences the gene expression of several environmentally-induced target genes, represses the expression of HdeA. HdeB, which is encoded within the same operon, may form heterodimers with HdeA. HdeA is a single domain α-helical []protein with an overall fold that is similar to the fold of the N-terminal subdomain of the GluRS anticodon-binding domain. This entry represents the acid stress chaperone HdeA superfamily.
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Publication
31630675 | J:287024
First Author: Bunda A
Year: 2019
Journal: Mol Brain
Title: Cacna1b alternative splicing impacts excitatory neurotransmission and is linked to behavioral responses to aversive stimuli.
Volume: 12
Issue: 1
Pages: 81
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Publication
- | J:44164
     
First Author: Williams R
Year: 1997
Journal: Personal Communication
Title: Email exchange
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Publication
7663435 | J:29617
First Author: Daniele A
Year: 1995
Journal: Biochem Mol Biol Int
Title: Expression of the two iduronate-2-sulfatase cDNAs.
Volume: 36
Issue: 2
Pages: 311-7
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Gene Segment
MGI:98625 | Trgc1
Type: gene_segment
Organism: mouse, laboratory
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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