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Type Details Score
Publication
32587658 | J:353691
 
First Author: Dunigan-Russell K
Year: 2020
Journal: Oxid Med Cell Longev
Title: Club Cell Heme Oxygenase-1 Deletion: Effects in Hyperoxia-Exposed Adult Mice.
Volume: 2020
Pages: 2908271
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HT Experiment
GSE190947 | Hepatocyte RNA-seq analysis in liver-specific XBP1 knockout mice fed a high fat sugar diet
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
29282254 | J:259211
First Author: Delpoux A
Year: 2018
Journal: J Exp Med
Title: Continuous activity of Foxo1 is required to prevent anergy and maintain the memory state of CD8+ T cells.
Volume: 215
Issue: 2
Pages: 575-594
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Publication
32507881 | J:296012
First Author: Fu A
Year: 2020
Journal: Biol Reprod
Title: IRX3 and IRX5 collaborate during ovary development and follicle formation to establish responsive granulosa cells in the adult mouse†.
Volume: 103
Issue: 3
Pages: 620-629
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GO Term
GO:0072690 | single-celled organism vegetative growth phase
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Publication
15923615 | J:99126
First Author: Zhang C
Year: 2005
Journal: Mol Cell Biol
Title: MafA is a key regulator of glucose-stimulated insulin secretion.
Volume: 25
Issue: 12
Pages: 4969-76
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CL Term
CL:0000113 | mononuclear phagocyte
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CL Term
CL:0000225 | anucleate cell
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CL Term
CL:0000226 | single nucleate cell
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CL Term
CL:0000988 | hematopoietic cell
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Publication
38582267 | J:349690
First Author: Kumar A
Year: 2024
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Therapeutic targeting of telomerase ameliorates experimental choroidal neovascularization.
Volume: 1870
Issue: 5
Pages: 167156
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Publication
31601272 | J:290680
First Author: Martínez de Paz A
Year: 2019
Journal: Epigenetics Chromatin
Title: MeCP2-E1 isoform is a dynamically expressed, weakly DNA-bound protein with different protein and DNA interactions compared to MeCP2-E2.
Volume: 12
Issue: 1
Pages: 63
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Publication
31297111 | J:281450
 
First Author: Mak A
Year: 2019
Journal: Front Immunol
Title: Deletion of CD137 Ligand Exacerbates Renal and Cutaneous but Alleviates Cerebral Manifestations in Lupus.
Volume: 10
Pages: 1411
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Publication
15039220 | J:89151
First Author: Hino A
Year: 2004
Journal: Am J Pathol
Title: Pathological role of large intestinal IL-12p40 for the induction of Th2-type allergic diarrhea.
Volume: 164
Issue: 4
Pages: 1327-35
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Publication
9916721 | J:124672
First Author: Oxenius A
Year: 1999
Journal: J Immunol
Title: IL-12 is not required for induction of type 1 cytokine responses in viral infections.
Volume: 162
Issue: 2
Pages: 965-73
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Publication
22802978 | J:192790
First Author: Masic A
Year: 2012
Journal: PLoS Negl Trop Dis
Title: Dendritic cell-mediated vaccination relies on interleukin-4 receptor signaling to avoid tissue damage after Leishmania major infection of BALB/c mice.
Volume: 6
Issue: 7
Pages: e1721
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Protein
E0CX19
Organism: Mus musculus/domesticus
Length: 311  
Fragment?: false
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Publication
17696994 | J:147480
First Author: Hodges A
Year: 2008
Journal: Genes Brain Behav
Title: Brain gene expression correlates with changes in behavior in the R6/1 mouse model of Huntington's disease.
Volume: 7
Issue: 3
Pages: 288-99
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Publication
12460553 | J:130975
First Author: Petersén A
Year: 2002
Journal: Neurobiol Dis
Title: Evidence for dysfunction of the nigrostriatal pathway in the R6/1 line of transgenic Huntington's disease mice.
Volume: 11
Issue: 1
Pages: 134-46
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Publication
15245475 | J:100257
First Author: Maatkamp A
Year: 2004
Journal: Eur J Neurosci
Title: Decrease of Hsp25 protein expression precedes degeneration of motoneurons in ALS-SOD1 mice.
Volume: 20
Issue: 1
Pages: 14-28
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Publication
15635146 | J:107649
First Author: Nishikawa A
Year: 2005
Journal: Toxicol Sci
Title: Induction of colon tumors in C57BL/6J mice fed MeIQx, IQ, or PhIP followed by dextran sulfate sodium treatment.
Volume: 84
Issue: 2
Pages: 243-8
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Publication
35388014 | J:323772
First Author: Lentini A
Year: 2022
Journal: Nat Commun
Title: Elastic dosage compensation by X-chromosome upregulation.
Volume: 13
Issue: 1
Pages: 1854
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Publication
17110436 | J:117147
First Author: Dragone LL
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Src-like adaptor protein (SLAP) regulates B cell receptor levels in a c-Cbl-dependent manner.
Volume: 103
Issue: 48
Pages: 18202-7
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Publication
19805133 | J:153686
First Author: Ruffell D
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: A CREB-C/EBPbeta cascade induces M2 macrophage-specific gene expression and promotes muscle injury repair.
Volume: 106
Issue: 41
Pages: 17475-80
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Publication
19841185 | J:157188
First Author: Lartigue A
Year: 2009
Journal: J Immunol
Title: Critical role of TLR2 and TLR4 in autoantibody production and glomerulonephritis in lpr mutation-induced mouse lupus.
Volume: 183
Issue: 10
Pages: 6207-16
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Publication
10906459 | J:63764
First Author: Schneider A
Year: 2000
Journal: Mech Dev
Title: Targeted disruption of the Nkx3.1 gene in mice results in morphogenetic defects of minor salivary glands: parallels to glandular duct morphogenesis in prostate.
Volume: 95
Issue: 1-2
Pages: 163-74
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Publication
20805469 | J:164373
First Author: Mariño G
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Insulin-like growth factor 1 treatment extends longevity in a mouse model of human premature aging by restoring somatotroph axis function.
Volume: 107
Issue: 37
Pages: 16268-73
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Publication
9987599 | -
First Author: Zlotnik A
Year: 1999
Journal: Crit Rev Immunol
Title: Recent advances in chemokines and chemokine receptors.
Volume: 19
Issue: 1
Pages: 1-47
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Publication
1935960 | -
First Author: Vambutas A
Year: 1991
Journal: Eur J Biochem
Title: Mitochondrial translational-initiation and elongation factors in Saccharomyces cerevisiae.
Volume: 201
Issue: 3
Pages: 643-52
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Publication
20807748 | J:164356
First Author: Portales-Casamar E
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: A regulatory toolbox of MiniPromoters to drive selective expression in the brain.
Volume: 107
Issue: 38
Pages: 16589-94
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Publication
2023927 | J:48913
First Author: Knebelmann B
Year: 1991
Journal: Proc Natl Acad Sci U S A
Title: Anti-Müllerian hormone Bruxelles: a nonsense mutation associated with the persistent Müllerian duct syndrome.
Volume: 88
Issue: 9
Pages: 3767-71
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Publication
15676279 | J:95949
First Author: Cho S
Year: 2005
Journal: Genomics
Title: The ribonuclease A superfamily of mammals and birds: identifying new members and tracing evolutionary histories.
Volume: 85
Issue: 2
Pages: 208-20
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Publication
21876757 | J:176344
First Author: Ratzka A
Year: 2011
Journal: PLoS One
Title: FGF-2 deficiency does not influence FGF ligand and receptor expression during development of the nigrostriatal system.
Volume: 6
Issue: 8
Pages: e23564
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Publication
25005473 | J:213846
First Author: Zalc A
Year: 2014
Journal: Development
Title: Antagonistic regulation of p57kip2 by Hes/Hey downstream of Notch signaling and muscle regulatory factors regulates skeletal muscle growth arrest.
Volume: 141
Issue: 14
Pages: 2780-90
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Publication
23825366 | J:222230
First Author: Talasila A
Year: 2013
Journal: Arterioscler Thromb Vasc Biol
Title: Myocardin regulates vascular response to injury through miR-24/-29a and platelet-derived growth factor receptor-β.
Volume: 33
Issue: 10
Pages: 2355-65
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Publication
21828096 | J:175836
First Author: Cariboni A
Year: 2011
Journal: Development
Title: VEGF signalling controls GnRH neuron survival via NRP1 independently of KDR and blood vessels.
Volume: 138
Issue: 17
Pages: 3723-33
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Publication
21718763 | J:176480
First Author: Eda A
Year: 2011
Journal: Gene
Title: Alteration of microRNA expression in the process of mouse brain growth.
Volume: 485
Issue: 1
Pages: 46-52
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Publication
12814555 | J:128154
First Author: Lammert E
Year: 2003
Journal: Curr Biol
Title: Role of VEGF-A in vascularization of pancreatic islets.
Volume: 13
Issue: 12
Pages: 1070-4
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Publication
33826897 | J:313893
First Author: Du J
Year: 2021
Journal: Cell Rep
Title: Arid1a-Plagl1-Hh signaling is indispensable for differentiation-associated cell cycle arrest of tooth root progenitors.
Volume: 35
Issue: 1
Pages: 108964
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Publication
11226283 | J:135466
First Author: Sullivan TJ
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: Lack of a role for transforming growth factor-beta in cytotoxic T lymphocyte antigen-4-mediated inhibition of T cell activation.
Volume: 98
Issue: 5
Pages: 2587-92
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Publication
9892646 | J:62502
First Author: Zhou D
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: A beta-1,3-N-acetylglucosaminyltransferase with poly-N-acetyllactosamine synthase activity is structurally related to beta-1,3-galactosyltransferases.
Volume: 96
Issue: 2
Pages: 406-11
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Publication
11562501 | J:71831
First Author: Olson JH
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: Allurin, a 21-kDa sperm chemoattractant from Xenopus egg jelly, is related to mammalian sperm-binding proteins.
Volume: 98
Issue: 20
Pages: 11205-10
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Publication
26554003 | J:228065
First Author: Goth CK
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: A systematic study of modulation of ADAM-mediated ectodomain shedding by site-specific O-glycosylation.
Volume: 112
Issue: 47
Pages: 14623-8
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Publication
25596276 | J:219576
First Author: McGreevy EM
Year: 2015
Journal: Biol Open
Title: Shroom3 functions downstream of planar cell polarity to regulate myosin II distribution and cellular organization during neural tube closure.
Volume: 4
Issue: 2
Pages: 186-96
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Publication
33443201 | J:300031
 
First Author: Collins KH
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: Adipose tissue is a critical regulator of osteoarthritis.
Volume: 118
Issue: 1
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Publication
32412585 | J:295320
First Author: Cox DC
Year: 2020
Journal: Hum Mol Genet
Title: Increased nuclear but not cytoplasmic activities of CELF1 protein leads to muscle wasting.
Volume: 29
Issue: 10
Pages: 1729-1744
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Publication
20818430 | J:165818
First Author: Rorke EA
Year: 2010
Journal: Oncogene
Title: AP1 factor inactivation in the suprabasal epidermis causes increased epidermal hyperproliferation and hyperkeratosis but reduced carcinogen-dependent tumor formation.
Volume: 29
Issue: 44
Pages: 5873-82
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Publication
21460835 | J:171377
First Author: Sahay A
Year: 2011
Journal: Nature
Title: Increasing adult hippocampal neurogenesis is sufficient to improve pattern separation.
Volume: 472
Issue: 7344
Pages: 466-70
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Publication
31873063 | J:328199
First Author: Christou M
Year: 2020
Journal: Nucleic Acid Ther
Title: Systemic Evaluation of Chimeric LNA/2'-O-Methyl Steric Blockers for Myotonic Dystrophy Type 1 Therapy.
Volume: 30
Issue: 2
Pages: 80-93
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Publication
2128800 | -
First Author: Bobik TA
Year: 1990
Journal: FEMS Microbiol Rev
Title: Formyl-methanofuran synthesis in Methanobacterium thermoautotrophicum.
Volume: 7
Issue: 3-4
Pages: 323-6
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Protein Domain
IPR012027 | Formylmethanofuran_DH_asu
Type: Family
Description: Formylmethanofuran dehydrogenase () is found in methanogenic and sulphate-reducing archaea. The enzyme contains molybdenum or tungsten, a molybdopterin guanine dinuceotide cofactor (MGD) and iron-sulphur clusters []. It catalyses the reversible reduction of CO2and methanofuran via N-carboxymethanofuran (carbamate) to N-formylmethanofuran, the first and second steps in methanogenesis from CO2[, ]. This reaction is important for the reduction of CO2to methane, in autotrophic CO2fixation, and in CO2formation from reduced C1units []. The synthesis of formylmethanofuran is crucial for the energy metabolism of archaea. Methanogenic archaea derives the energy for autrophic growth from the reduction of CO2with molecular hydrogen as the electron donor []. The process of methanogenesis consists of a series of reduction reactions at which the one-carbon unit derived from CO2is bound to C1carriers.There are two isoenzymes of formylmethanofuran dehydrogenase: a tungsten-containing isoenzyme (Fwd) and a molybdenum-containing isoenzyme (Fmd). The tungsten isoenzyme is constitutively transcribed, whereas transcription of the molybdenum operon is induced by molybdate []. The archaean Methanobacterium thermoautotrophicum contains a 4-subunit (FwdA, FwdB, FwdC, FwdD) tungsten formylmethanofuran dehydrogenase and a 3-subunit (FmdA, FmdB, FmdC) molybdenum formylmethanofuran dehydrogenase [].This entry represents subunit A (FmdA and FwdA) of formylmethanofuran dehydrogenases. The other subunits are subunit B (), subunit C (), subunit D (), subunit E (), and subunit F. Some organisms also encode a fusion of the C and D subunits(). Members of this entry share sequence similarity with the two highly conserved regions of dihydroorotase () (an amidohydrolase): the first is located at the N-terminal end and contains two histidine residues suggested to be involved in binding a zinc ion []; the second conserved region is at the C terminus [].In Methylobacterium extorquens, homologues of FmdA, FmdB and FmdC subunits were found and shown to copurify with a functional formyltransferase complex. However, there is no evidence that the complex catalyses the oxidation of formylmethanofuran [].Methanogenic bacteria and archea derive the energy for autotrophic growth from methanogenesis, the reduction of CO2 with molecular hydrogen as the electron donor. FMDH catalyzes the first step in methanogenesis, the formyl-methanofuran synthesis. In this step, CO2 is bound to methanofuran and subsequently reduced to the formyl state with electrons derived from hydrogen [, ].
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Publication
30980961 | J:276706
 
First Author: Meguro F
Year: 2019
Journal: Gene Expr Patterns
Title: Bmp signaling in molar cusp formation.
Volume: 32
Pages: 67-71
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Publication
33374598 | J:348434
 
First Author: Eltokhi A
Year: 2020
Journal: Int J Mol Sci
Title: Glutamatergic Dysfunction and Synaptic Ultrastructural Alterations in Schizophrenia and Autism Spectrum Disorder: Evidence from Human and Rodent Studies.
Volume: 22
Issue: 1
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Publication
21145759 | J:167293
First Author: Procaccini C
Year: 2010
Journal: Immunity
Title: An oscillatory switch in mTOR kinase activity sets regulatory T cell responsiveness.
Volume: 33
Issue: 6
Pages: 929-41
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Protein Coding Gene
MGI:2441689 | Fem1al
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
29526794 | J:280442
 
First Author: Fernandes KA
Year: 2018
Journal: Exp Eye Res
Title: Role of SARM1 and DR6 in retinal ganglion cell axonal and somal degeneration following axonal injury.
Volume: 171
Pages: 54-61
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Publication
35432331 | J:323920
 
First Author: Borroto A
Year: 2022
Journal: Front Immunol
Title: Mutation of the Polyproline Sequence in CD3ε Evidences TCR Signaling Requirements for Differentiation and Function of Pro-Inflammatory Tγδ17 Cells.
Volume: 13
Pages: 799919
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Publication
20944652 | J:180850
First Author: Mukhopadhyay A
Year: 2011
Journal: J Invest Dermatol
Title: Activated Kras alters epidermal homeostasis of mouse skin, resulting in redundant skin and defective hair cycling.
Volume: 131
Issue: 2
Pages: 311-9
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Publication
28351977 | J:242144
First Author: Luo D
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Deltex2 represses MyoD expression and inhibits myogenic differentiation by acting as a negative regulator of Jmjd1c.
Volume: 114
Issue: 15
Pages: E3071-E3080
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Publication
21098124 | J:169423
First Author: Mylona A
Year: 2011
Journal: Mol Cell Biol
Title: The essential function for serum response factor in T-cell development reflects its specific coupling to extracellular signal-regulated kinase signaling.
Volume: 31
Issue: 2
Pages: 267-76
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Protein Coding Gene
MGI:1927170 | Afg2a
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
30150306 | J:266082
First Author: Horwitz E
Year: 2018
Journal: Diabetes
Title: β-Cell DNA Damage Response Promotes Islet Inflammation in Type 1 Diabetes.
Volume: 67
Issue: 11
Pages: 2305-2318
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Publication
12540780 | J:105813
First Author: Kato A
Year: 2003
Journal: Hepatology
Title: Endogenous IL-13 protects hepatocytes and vascular endothelial cells during ischemia/reperfusion injury.
Volume: 37
Issue: 2
Pages: 304-12
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Publication
15163631 | J:91057
First Author: Louvi A
Year: 2004
Journal: Development
Title: Presenilin 1 in migration and morphogenesis in the central nervous system.
Volume: 131
Issue: 13
Pages: 3093-105
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Publication
25733102 | J:316464
 
First Author: Larochelle A
Year: 2015
Journal: Brain Behav Immun
Title: Role of adaptor protein MyD88 in TLR-mediated preconditioning and neuroprotection after acute excitotoxicity.
Volume: 46
Pages: 221-31
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Publication
25824710 | J:222418
First Author: Czechanski A
Year: 2015
Journal: Dev Biol
Title: Kif18a is specifically required for mitotic progression during germ line development.
Volume: 402
Issue: 2
Pages: 253-262
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Publication
30289385 | -
   
First Author: Butryn A
Year: 2018
Journal: Elife
Title: Crystal structure of the full Swi2/Snf2 remodeler Mot1 in the resting state.
Volume: 7
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Publication
16650980 | -
First Author: Torres-Larios A
Year: 2006
Journal: Curr Opin Struct Biol
Title: Structure of ribonuclease P--a universal ribozyme.
Volume: 16
Issue: 3
Pages: 327-35
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Publication
16178819 | -
First Author: Breier A
Year: 2005
Journal: Curr Cancer Drug Targets
Title: P-glycoprotein--implications of metabolism of neoplastic cells and cancer therapy.
Volume: 5
Issue: 6
Pages: 457-68
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Publication
9043106 | -
 
First Author: Negredo A
Year: 1997
Journal: Microbiology
Title: Cloning, analysis and one-step disruption of the ARG5,6 gene of Candida albicans.
Volume: 143 ( Pt 2)
Pages: 297-302
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Publication
8098217 | J:12885
First Author: Angel JM
Year: 1993
Journal: Mol Carcinog
Title: Localization of a novel chromosome 7 locus that suppresses development of N-Methyl-N-nitrosourea-induced murine thymic lymphomas.
Volume: 7
Issue: 3
Pages: 151-6
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Publication
30640943 | J:270311
First Author: Rando A
Year: 2019
Journal: PLoS One
Title: Chemotherapeutic agent 5-fluorouracil increases survival of SOD1 mouse model of ALS.
Volume: 14
Issue: 1
Pages: e0210752
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Publication
30134203 | J:267047
 
First Author: Masala A
Year: 2018
Journal: Neuroscience
Title: Epigenetic Changes Associated with the Expression of Amyotrophic Lateral Sclerosis (ALS) Causing Genes.
Volume: 390
Pages: 1-11
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Publication
31923399 | J:291950
First Author: Jarret A
Year: 2020
Journal: Cell
Title: Enteric Nervous System-Derived IL-18 Orchestrates Mucosal Barrier Immunity.
Volume: 180
Issue: 1
Pages: 50-63.e12
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Publication
19478335 | J:152624
First Author: Wu Y
Year: 2009
Journal: J Biol Chem
Title: Novel lipofuscin bisretinoids prominent in human retina and in a model of recessive Stargardt disease.
Volume: 284
Issue: 30
Pages: 20155-66
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Publication
32946951 | J:299687
 
First Author: Diab A
Year: 2020
Journal: Neuroscience
Title: NCK1 Regulates Amygdala Activity to Control Context-dependent Stress Responses and Anxiety in Male Mice.
Volume: 448
Pages: 107-125
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Publication
8986768 | J:37440
First Author: Guimarães MJ
Year: 1996
Journal: Proc Natl Acad Sci U S A
Title: Identification of a novel selD homolog from eukaryotes, bacteria, and archaea: is there an autoregulatory mechanism in selenocysteine metabolism?
Volume: 93
Issue: 26
Pages: 15086-91
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Publication
19541844 | J:171488
First Author: Wu S
Year: 2010
Journal: Am J Respir Cell Mol Biol
Title: Conditional overexpression of connective tissue growth factor disrupts postnatal lung development.
Volume: 42
Issue: 5
Pages: 552-63
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Publication
9042856 | -
First Author: Wissmann A
Year: 1997
Journal: Genes Dev
Title: Caenorhabditis elegans LET-502 is related to Rho-binding kinases and human myotonic dystrophy kinase and interacts genetically with a homolog of the regulatory subunit of smooth muscle myosin phosphatase to affect cell shape.
Volume: 11
Issue: 4
Pages: 409-22
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Publication
34038728 | J:307115
First Author: Nanou A
Year: 2021
Journal: Cell Rep
Title: Endothelial Tpl2 regulates vascular barrier function via JNK-mediated degradation of claudin-5 promoting neuroinflammation or tumor metastasis.
Volume: 35
Issue: 8
Pages: 109168
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Publication
31663507 | J:282769
   
First Author: Kerlin A
Year: 2019
Journal: Elife
Title: Functional clustering of dendritic activity during decision-making.
Volume: 8
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Publication
37778436 | J:355574
 
First Author: Brodovskaya A
Year: 2023
Journal: Prog Neurobiol
Title: Neuronal plasticity contributes to postictal death.
Volume: 231
Pages: 102531
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Publication
8615815 | J:32790
 
First Author: Beynon RJ
Year: 1996
Journal: Biochem J
Title: Characterization of the soluble, secreted form of urinary meprin.
Volume: 315 ( Pt 2)
Pages: 461-5
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Publication
9161413 | J:40070
First Author: Jiang W
Year: 1997
Journal: Gene
Title: Correlation of the exon/intron organization to the secondary structures of the protease domain of mouse meprin alpha subunit.
Volume: 189
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