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Search results 1901 to 2000 out of 2007 for Arpp21

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Type Details Score
Publication
38831312 | J:351190
First Author: Wang X
Year: 2024
Journal: Alzheimers Res Ther
Title: Intermittent hypoxia training enhances Aβ endocytosis by plaque associated microglia via VPS35-dependent TREM2 recycling in murine Alzheimer's disease.
Volume: 16
Issue: 1
Pages: 121
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Publication
36603748 | J:333422
 
First Author: Tohumeken S
Year: 2023
Journal: Neurobiol Dis
Title: Neuronal deletion of nSMase2 reduces the production of Aβ and directly protects neurons.
Volume: 177
Pages: 105987
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Publication
24742670 | J:215945
First Author: Sullivan SE
Year: 2014
Journal: J Biol Chem
Title: Mint proteins are required for synaptic activity-dependent amyloid precursor protein (APP) trafficking and amyloid β generation.
Volume: 289
Issue: 22
Pages: 15374-83
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Publication
31924799 | J:285645
First Author: Pi G
Year: 2020
Journal: Nat Commun
Title: Posterior basolateral amygdala to ventral hippocampal CA1 drives approach behaviour to exert an anxiolytic effect.
Volume: 11
Issue: 1
Pages: 183
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Publication
35883442 | J:345094
 
First Author: Xu G
Year: 2022
Journal: Biomolecules
Title: Modeling the Competition between Misfolded Aβ Conformers That Produce Distinct Types of Amyloid Pathology in Alzheimer's Disease.
Volume: 12
Issue: 7
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Publication
36912451 | J:348477
 
First Author: Sai K
Year: 2023
Journal: J Cell Sci
Title: Aberrantly activated TAK1 links neuroinflammation and neuronal loss in Alzheimer's disease mouse models.
Volume: 136
Issue: 6
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Publication
35511433 | J:325320
 
First Author: Yan P
Year: 2022
Journal: J Clin Invest
Title: Peripheral monocyte-derived cells counter amyloid plaque pathogenesis in a mouse model of Alzheimer's disease.
Volume: 132
Issue: 11
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Publication
24218590 | J:348499
First Author: Burke RM
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: BMP9 ameliorates amyloidosis and the cholinergic defect in a mouse model of Alzheimer's disease.
Volume: 110
Issue: 48
Pages: 19567-72
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Publication
35293016 | J:348512
First Author: Huffels CFM
Year: 2022
Journal: J Neurosci Res
Title: Calcium signaling in individual APP/PS1 mouse dentate gyrus astrocytes increases ex vivo with Aβ pathology and age without affecting astrocyte network activity.
Volume: 100
Issue: 6
Pages: 1281-1295
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Publication
35584626 | J:348528
First Author: Kass B
Year: 2022
Journal: Cell Rep Med
Title: Aβ oligomer concentration in mouse and human brain and its drug-induced reduction ex vivo.
Volume: 3
Issue: 5
Pages: 100630
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Publication
27421117 | J:252385
First Author: Hansen HH
Year: 2016
Journal: PLoS One
Title: Long-Term Treatment with Liraglutide, a Glucagon-Like Peptide-1 (GLP-1) Receptor Agonist, Has No Effect on β-Amyloid Plaque Load in Two Transgenic APP/PS1 Mouse Models of Alzheimer's Disease.
Volume: 11
Issue: 7
Pages: e0158205
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Publication
37193408 | J:351758
First Author: Ogbeide-Latario OE
Year: 2022
Journal: Sleep Adv
Title: Two novel mouse models of slow-wave-sleep enhancement in aging and Alzheimer's disease.
Volume: 3
Issue: 1
Pages: zpac022
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Publication
34215298 | J:324340
First Author: Sharoar MG
Year: 2021
Journal: Mol Neurodegener
Title: Accumulation of saposin in dystrophic neurites is linked to impaired lysosomal functions in Alzheimer's disease brains.
Volume: 16
Issue: 1
Pages: 45
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Publication
35606145 | J:348877
First Author: Wang LH
Year: 2022
Journal: J Neurosci
Title: Calpain-2 Mediates MBNL2 Degradation and a Developmental RNA Processing Program in Neurodegeneration.
Volume: 42
Issue: 25
Pages: 5102-5114
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Publication
30082275 | J:266690
First Author: Kang SS
Year: 2018
Journal: J Exp Med
Title: Microglial translational profiling reveals a convergent APOE pathway from aging, amyloid, and tau.
Volume: 215
Issue: 9
Pages: 2235-2245
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Publication
30189209 | J:269833
First Author: Eftekharzadeh B
Year: 2018
Journal: Neuron
Title: Tau Protein Disrupts Nucleocytoplasmic Transport in Alzheimer's Disease.
Volume: 99
Issue: 5
Pages: 925-940.e7
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Publication
33314529 | J:331908
First Author: Audrain M
Year: 2021
Journal: Alzheimers Dement
Title: Reactive or transgenic increase in microglial TYROBP reveals a TREM2-independent TYROBP-APOE link in wild-type and Alzheimer's-related mice.
Volume: 17
Issue: 2
Pages: 149-163
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Publication
36879321 | J:345381
First Author: Aloi MS
Year: 2023
Journal: J Neuroinflammation
Title: Microglia specific deletion of miR-155 in Alzheimer's disease mouse models reduces amyloid-β pathology but causes hyperexcitability and seizures.
Volume: 20
Issue: 1
Pages: 60
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Publication
28667669 | J:274704
First Author: Perusini JN
Year: 2017
Journal: Hippocampus
Title: Optogenetic stimulation of dentate gyrus engrams restores memory in Alzheimer's disease mice.
Volume: 27
Issue: 10
Pages: 1110-1122
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Publication
16899370 | J:113199
First Author: Burgess BL
Year: 2006
Journal: Neurobiol Dis
Title: Elevated plasma triglyceride levels precede amyloid deposition in Alzheimer's disease mouse models with abundant A beta in plasma.
Volume: 24
Issue: 1
Pages: 114-27
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Publication
30704515 | J:273177
First Author: Gerber H
Year: 2019
Journal: Acta Neuropathol Commun
Title: The APMAP interactome reveals new modulators of APP processing and beta-amyloid production that are altered in Alzheimer's disease.
Volume: 7
Issue: 1
Pages: 13
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Publication
32699218 | J:294065
First Author: Hunsberger HC
Year: 2020
Journal: Sci Rep
Title: Divergence in the metabolome between natural aging and Alzheimer's disease.
Volume: 10
Issue: 1
Pages: 12171
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Publication
35914577 | J:353150
 
First Author: Ferrari LL
Year: 2022
Journal: J Neurosci Methods
Title: Validation of DREADD agonists and administration route in a murine model of sleep enhancement.
Volume: 380
Pages: 109679
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Publication
29518357 | J:262250
First Author: Lee CYD
Year: 2018
Journal: Neuron
Title: Elevated TREM2 Gene Dosage Reprograms Microglia Responsivity and Ameliorates Pathological Phenotypes in Alzheimer's Disease Models.
Volume: 97
Issue: 5
Pages: 1032-1048.e5
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Publication
24732467 | J:215221
First Author: Mellott TJ
Year: 2014
Journal: PLoS One
Title: IGF2 ameliorates amyloidosis, increases cholinergic marker expression and raises BMP9 and neurotrophin levels in the hippocampus of the APPswePS1dE9 Alzheimer's disease model mice.
Volume: 9
Issue: 4
Pages: e94287
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Publication
33766652 | J:307687
 
First Author: William CM
Year: 2021
Journal: Neurobiol Dis
Title: Impairment of visual cortical plasticity by amyloid-beta species.
Volume: 154
Pages: 105344
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Publication
30879788 | J:352674
First Author: Martorell AJ
Year: 2019
Journal: Cell
Title: Multi-sensory Gamma Stimulation Ameliorates Alzheimer's-Associated Pathology and Improves Cognition.
Volume: 177
Issue: 2
Pages: 256-271.e22
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Publication
24894464 | J:213265
 
First Author: Wu H
Year: 2014
Journal: Elife
Title: Complete morphologies of basal forebrain cholinergic neurons in the mouse.
Volume: 3
Pages: e02444
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Publication
35465615 | J:349607
 
First Author: DeFlitch L
Year: 2022
Journal: Front Cell Neurosci
Title: Age and Alzheimer's Disease-Related Oligodendrocyte Changes in Hippocampal Subregions.
Volume: 16
Pages: 847097
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Publication
32514139 | J:298290
First Author: Poll S
Year: 2020
Journal: Nat Neurosci
Title: Memory trace interference impairs recall in a mouse model of Alzheimer's disease.
Volume: 23
Issue: 8
Pages: 952-958
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Publication
35045289 | J:324407
First Author: Zarhin D
Year: 2022
Journal: Cell Rep
Title: Disrupted neural correlates of anesthesia and sleep reveal early circuit dysfunctions in Alzheimer models.
Volume: 38
Issue: 3
Pages: 110268
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Publication
35106851 | J:349998
First Author: Lee J
Year: 2022
Journal: Glia
Title: Longitudinal intravital imaging of cerebral microinfarction reveals a dynamic astrocyte reaction leading to glial scar formation.
Volume: 70
Issue: 5
Pages: 975-988
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Publication
39266475 | J:360724
First Author: Park S
Year: 2024
Journal: Exp Neurobiol
Title: FAM19A5 Deficiency Mitigates the Aβ Plaque Burden and Improves Cognition in Mouse Models of Alzheimer's Disease.
Volume: 33
Issue: 4
Pages: 193-201
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Publication
37531953 | J:351104
 
First Author: Wellman SM
Year: 2023
Journal: J Neural Eng
Title: Aberrant accumulation of age- and disease-associated factors following neural probe implantation in a mouse model of Alzheimer's disease.
Volume: 20
Issue: 4
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Genotype
Genotype
Symbol: Apmap/Apmap Tg(APPswe,PSEN1dE9)85Dbo/?
Background: involves: C57BL/6J * C57BL/6N
Zygosity: cx
Has Mutant Allele: true
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Publication
29295920 | J:348411
First Author: Han KH
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Migration-based selections of antibodies that convert bone marrow into trafficking microglia-like cells that reduce brain amyloid β.
Volume: 115
Issue: 3
Pages: E372-E381
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Publication
35915180 | J:335653
First Author: Liu CC
Year: 2022
Journal: Nat Neurosci
Title: Peripheral apoE4 enhances Alzheimer's pathology and impairs cognition by compromising cerebrovascular function.
Volume: 25
Issue: 8
Pages: 1020-1033
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Publication
31878951 | J:341565
First Author: Pandey RS
Year: 2019
Journal: Mol Neurodegener
Title: Genetic perturbations of disease risk genes in mice capture transcriptomic signatures of late-onset Alzheimer's disease.
Volume: 14
Issue: 1
Pages: 50
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Publication
26758846 | J:228864
First Author: Lian H
Year: 2016
Journal: J Neurosci
Title: Astrocyte-Microglia Cross Talk through Complement Activation Modulates Amyloid Pathology in Mouse Models of Alzheimer's Disease.
Volume: 36
Issue: 2
Pages: 577-89
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Publication
33846335 | J:311263
First Author: Kim K
Year: 2021
Journal: Nat Commun
Title: Therapeutic B-cell depletion reverses progression of Alzheimer's disease.
Volume: 12
Issue: 1
Pages: 2185
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Publication
25331900 | J:216662
First Author: Chow HM
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: CDK5 activator protein p25 preferentially binds and activates GSK3β.
Volume: 111
Issue: 45
Pages: E4887-95
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Publication
25002035 | J:218071
First Author: Orre M
Year: 2014
Journal: Neurobiol Aging
Title: Isolation of glia from Alzheimer's mice reveals inflammation and dysfunction.
Volume: 35
Issue: 12
Pages: 2746-2760
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Publication
35236988 | J:338102
First Author: Xiong J
Year: 2022
Journal: Nature
Title: FSH blockade improves cognition in mice with Alzheimer's disease.
Volume: 603
Issue: 7901
Pages: 470-476
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Publication
23432034 | J:199628
First Author: Chakravarthy B
Year: 2013
Journal: J Neurochem
Title: A synthetic peptide corresponding to a region of the human pericentriolar material 1 (PCM-1) protein binds β-amyloid (Aβ1-42 ) oligomers.
Volume: 126
Issue: 3
Pages: 415-24
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Publication
33791294 | J:318609
 
First Author: Huang X
Year: 2021
Journal: Front Cell Dev Biol
Title: Tetramethylpyrazine Improves Cognitive Impairment and Modifies the Hippocampal Proteome in Two Mouse Models of Alzheimer's Disease.
Volume: 9
Pages: 632843
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Publication
25673868 | J:219873
First Author: Ben Haim L
Year: 2015
Journal: J Neurosci
Title: The JAK/STAT3 pathway is a common inducer of astrocyte reactivity in Alzheimer's and Huntington's diseases.
Volume: 35
Issue: 6
Pages: 2817-29
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Publication
29113959 | J:260831
 
First Author: Lardenoije R
Year: 2018
Journal: Mol Cell Neurosci
Title: Age-related epigenetic changes in hippocampal subregions of four animal models of Alzheimer's disease.
Volume: 86
Pages: 1-15
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Publication
37358017 | J:339350
First Author: Marinho D
Year: 2023
Journal: Aging Cell
Title: Reduction of class I histone deacetylases ameliorates ER-mitochondria cross-talk in Alzheimer's disease.
Volume: 22
Issue: 8
Pages: e13895
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Publication
29211722 | J:274288
First Author: Sorrentino V
Year: 2017
Journal: Nature
Title: Enhancing mitochondrial proteostasis reduces amyloid-β proteotoxicity.
Volume: 552
Issue: 7684
Pages: 187-193
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Publication
28683325 | J:254503
First Author: Haas LT
Year: 2017
Journal: Cell Rep
Title: Silent Allosteric Modulation of mGluR5 Maintains Glutamate Signaling while Rescuing Alzheimer's Mouse Phenotypes.
Volume: 20
Issue: 1
Pages: 76-88
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Publication
30867420 | J:273276
First Author: He Y
Year: 2019
Journal: Nat Commun
Title: Amyloid β oligomers suppress excitatory transmitter release via presynaptic depletion of phosphatidylinositol-4,5-bisphosphate.
Volume: 10
Issue: 1
Pages: 1193
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Publication
35961653 | J:352637
First Author: Israel LL
Year: 2022
Journal: ACS Nano
Title: Signature Effects of Vector-Guided Systemic Nano Bioconjugate Delivery Across Blood-Brain Barrier of Normal, Alzheimer's, and Tumor Mouse Models.
Volume: 16
Issue: 8
Pages: 11815-11832
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Publication
33672482 | J:352640
 
First Author: Drews HJ
Year: 2021
Journal: Pharmaceuticals (Basel)
Title: Losartan Improves Memory, Neurogenesis and Cell Motility in Transgenic Alzheimer's Mice.
Volume: 14
Issue: 2
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Publication
23534431 | J:352629
First Author: Stargardt A
Year: 2013
Journal: Aging Cell
Title: Reduced amyloid-β degradation in early Alzheimer's disease but not in the APPswePS1dE9 and 3xTg-AD mouse models.
Volume: 12
Issue: 3
Pages: 499-507
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Publication
22912745 | J:189978
First Author: Kamphuis W
Year: 2012
Journal: PLoS One
Title: GFAP isoforms in adult mouse brain with a focus on neurogenic astrocytes and reactive astrogliosis in mouse models of Alzheimer disease.
Volume: 7
Issue: 8
Pages: e42823
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Publication
33663578 | J:311283
First Author: Chen M
Year: 2021
Journal: Mol Neurodegener
Title: Enhancing GABAergic signaling ameliorates aberrant gamma oscillations of olfactory bulb in AD mouse models.
Volume: 16
Issue: 1
Pages: 14
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Publication
33863723 | J:358337
 
First Author: Chen G
Year: 2021
Journal: Sci Adv
Title: Netrin-1 receptor UNC5C cleavage by active δ-secretase enhances neurodegeneration, promoting Alzheimer's disease pathologies.
Volume: 7
Issue: 16
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Publication
35339896 | J:322782
 
First Author: Zhou Q
Year: 2022
Journal: EBioMedicine
Title: Human tau accumulation promotes glycogen synthase kinase-3β acetylation and thus upregulates the kinase: A vicious cycle in Alzheimer neurodegeneration.
Volume: 78
Pages: 103970
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Publication
32404941 | J:348427
First Author: Song G
Year: 2020
Journal: Sci Rep
Title: Multimodal Coherent Imaging of Retinal Biomarkers of Alzheimer's Disease in a Mouse Model.
Volume: 10
Issue: 1
Pages: 7912
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Publication
38476461 | J:346241
 
First Author: Devadoss D
Year: 2024
Journal: Front Mol Neurosci
Title: LRRC25 expression during physiological aging and in mouse models of Alzheimer's disease and iPSC-derived neurons.
Volume: 17
Pages: 1365752
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Publication
27425620 | J:238659
First Author: Liebmann T
Year: 2016
Journal: Cell Rep
Title: Three-Dimensional Study of Alzheimer's Disease Hallmarks Using the iDISCO Clearing Method.
Volume: 16
Issue: 4
Pages: 1138-1152
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Publication
30742114 | J:277544
First Author: Fang EF
Year: 2019
Journal: Nat Neurosci
Title: Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer's disease.
Volume: 22
Issue: 3
Pages: 401-412
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Publication
35775150 | J:349319
First Author: Vande Vyver M
Year: 2022
Journal: Epilepsia
Title: Higher susceptibility to 6 Hz corneal kindling and lower responsiveness to antiseizure drugs in mouse models of Alzheimer's disease.
Volume: 63
Issue: 10
Pages: 2703-2715
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Publication
33955647 | J:311343
First Author: Wu L
Year: 2021
Journal: Aging Cell
Title: Therapeutic efficacy of novel memantine nitrate MN-08 in animal models of Alzheimer's disease.
Volume: 20
Issue: 6
Pages: e13371
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Publication
31737743 | J:352853
First Author: Wang S
Year: 2019
Journal: Neurophotonics
Title: Label-free multiphoton imaging of β-amyloid plaques in Alzheimer's disease mouse models.
Volume: 6
Issue: 4
Pages: 045008
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Publication
25617315 | J:232678
First Author: Clarke JR
Year: 2015
Journal: EMBO Mol Med
Title: Alzheimer-associated Aβ oligomers impact the central nervous system to induce peripheral metabolic deregulation.
Volume: 7
Issue: 2
Pages: 190-210
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Publication
27752775 | J:311368
First Author: Jan A
Year: 2017
Journal: Acta Neuropathol
Title: eEF2K inhibition blocks Aβ42 neurotoxicity by promoting an NRF2 antioxidant response.
Volume: 133
Issue: 1
Pages: 101-119
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Publication
26982728 | J:232713
First Author: Roy DS
Year: 2016
Journal: Nature
Title: Memory retrieval by activating engram cells in mouse models of early Alzheimer's disease.
Volume: 531
Issue: 7595
Pages: 508-12
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Publication
26280122 | J:228804
First Author: Ceglia I
Year: 2015
Journal: Nat Med
Title: APP intracellular domain-WAVE1 pathway reduces amyloid-β production.
Volume: 21
Issue: 9
Pages: 1054-9
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Publication
27210751 | J:235961
First Author: Hamilton A
Year: 2016
Journal: Cell Rep
Title: Chronic Pharmacological mGluR5 Inhibition Prevents Cognitive Impairment and Reduces Pathogenesis in an Alzheimer Disease Mouse Model.
Volume: 15
Issue: 9
Pages: 1859-65
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Publication
38502413 | J:350687
     
First Author: Kong Y
Year: 2024
Journal: Mol Neurobiol
Title: Relationship Between Reactive Astrocytes, by [(18)F]SMBT-1 Imaging, with Amyloid-Beta, Tau, Glucose Metabolism, and TSPO in Mouse Models of Alzheimer's Disease.
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Publication
32849642 | J:319606
 
First Author: Zhao J
Year: 2020
Journal: Front Immunol
Title: Administration of Amyloid Precursor Protein Gene Deleted Mouse ESC-Derived Thymic Epithelial Progenitors Attenuates Alzheimer's Pathology.
Volume: 11
Pages: 1781
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Publication
24684630 | J:214689
First Author: Kuwabara Y
Year: 2014
Journal: J Neurochem
Title: Impairments of long-term depression induction and motor coordination precede Aβ accumulation in the cerebellum of APPswe/PS1dE9 double transgenic mice.
Volume: 130
Issue: 3
Pages: 432-43
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Publication
34099706 | J:322192
First Author: Fitz NF
Year: 2021
Journal: Nat Commun
Title: Phospholipids of APOE lipoproteins activate microglia in an isoform-specific manner in preclinical models of Alzheimer's disease.
Volume: 12
Issue: 1
Pages: 3416
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Publication
30506549 | J:327646
First Author: De Rossi P
Year: 2019
Journal: Brain Pathol
Title: Aberrant accrual of BIN1 near Alzheimer's disease amyloid deposits in transgenic models.
Volume: 29
Issue: 4
Pages: 485-501
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Publication
25622143 | J:274055
First Author: Orr AG
Year: 2015
Journal: Nat Neurosci
Title: Astrocytic adenosine receptor A2A and Gs-coupled signaling regulate memory.
Volume: 18
Issue: 3
Pages: 423-34
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Publication
28591834 | J:277756
First Author: Lu NN
Year: 2018
Journal: Cereb Cortex
Title: Cholinergic Grb2-Associated-Binding Protein 1 Regulates Cognitive Function.
Volume: 28
Issue: 7
Pages: 2391-2404
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Publication
27569580 | J:258151
 
First Author: Melnikova T
Year: 2016
Journal: Neurobiol Dis
Title: Sex-related dimorphism in dentate gyrus atrophy and behavioral phenotypes in an inducible tTa:APPsi transgenic model of Alzheimer's disease.
Volume: 96
Pages: 171-185
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Publication
25878292 | J:221673
First Author: Hall AM
Year: 2015
Journal: J Neurosci
Title: Tau-dependent Kv4.2 depletion and dendritic hyperexcitability in a mouse model of Alzheimer's disease.
Volume: 35
Issue: 15
Pages: 6221-30
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Publication
37973869 | J:348885
First Author: Zielinski M
Year: 2023
Journal: Nat Neurosci
Title: Cryo-EM of Aβ fibrils from mouse models find tg-APP(ArcSwe) fibrils resemble those found in patients with sporadic Alzheimer's disease.
Volume: 26
Issue: 12
Pages: 2073-2080
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Publication
30414727 | J:272048
 
First Author: Midani-Kurçak JS
Year: 2019
Journal: Brain Res
Title: Effect of tau-pathology on charged multivesicular body protein 2b (CHMP2B).
Volume: 1706
Pages: 224-236
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Publication
16753269 | J:111748
First Author: Melnikova T
Year: 2006
Journal: Neuroscience
Title: Cycloxygenase-2 activity promotes cognitive deficits but not increased amyloid burden in a model of Alzheimer's disease in a sex-dimorphic pattern.
Volume: 141
Issue: 3
Pages: 1149-62
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Publication
34102111 | J:325335
First Author: Chen JF
Year: 2021
Journal: Neuron
Title: Enhancing myelin renewal reverses cognitive dysfunction in a murine model of Alzheimer's disease.
Volume: 109
Issue: 14
Pages: 2292-2307.e5
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Publication
29186695 | J:255230
First Author: Savas JN
Year: 2017
Journal: Cell Rep
Title: Amyloid Accumulation Drives Proteome-wide Alterations in Mouse Models of Alzheimer's Disease-like Pathology.
Volume: 21
Issue: 9
Pages: 2614-2627
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Publication
18753367 | J:138796
First Author: Matsuda S
Year: 2008
Journal: J Neurosci
Title: BRI2 inhibits amyloid beta-peptide precursor protein processing by interfering with the docking of secretases to the substrate.
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