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Search results 1901 to 2000 out of 4306 for C3

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Type Details Score
Publication
35798767 | J:326532
First Author: Gilson Sena IF
Year: 2022
Journal: Sci Rep
Title: Identification of early biomarkers in saliva in genetically engineered mouse model C(3)1-TAg of breast cancer.
Volume: 12
Issue: 1
Pages: 11544
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Strain
MGI:5438781 | B6N.129S6-Sphk1<tm1Rlp>/J
Attribute String: congenic, mutant strain, targeted mutation
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Publication
28276483 | J:275307
 
First Author: Siedlinski M
Year: 2017
Journal: Sci Rep
Title: Vascular transcriptome profiling identifies Sphingosine kinase 1 as a modulator of angiotensin II-induced vascular dysfunction.
Volume: 7
Pages: 44131
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Publication
30963576 | J:276953
First Author: Jiang ZJ
Year: 2019
Journal: J Neurochem
Title: Extracellular and intracellular sphingosine-1-phosphate distinctly regulates exocytosis in chromaffin cells.
Volume: 149
Issue: 6
Pages: 729-746
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Publication
19168577 | J:149705
First Author: Wadgaonkar R
Year: 2009
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Differential regulation of sphingosine kinases 1 and 2 in lung injury.
Volume: 296
Issue: 4
Pages: L603-13
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Publication
27417539 | J:240826
 
First Author: Sun K
Year: 2016
Journal: Nat Commun
Title: Sphingosine-1-phosphate promotes erythrocyte glycolysis and oxygen release for adaptation to high-altitude hypoxia.
Volume: 7
Pages: 12086
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Publication
31416077 | J:294582
First Author: Zhang X
Year: 2019
Journal: Am J Nephrol
Title: Knockout of Sphingosine Kinase 1 Attenuates Renal Fibrosis in Unilateral Ureteral Obstruction Model.
Volume: 50
Issue: 3
Pages: 196-203
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Publication
25460165 | J:225697
First Author: Snider AJ
Year: 2014
Journal: PLoS One
Title: Distinct roles for hematopoietic and extra-hematopoietic sphingosine kinase-1 in inflammatory bowel disease.
Volume: 9
Issue: 12
Pages: e113998
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Publication
25002116 | J:217572
First Author: Kim EY
Year: 2014
Journal: FASEB J
Title: Role of sphingosine kinase 1 and sphingosine-1-phosphate in CD40 signaling and IgE class switching.
Volume: 28
Issue: 10
Pages: 4347-58
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Publication
18199826 | J:133607
First Author: Li X
Year: 2008
Journal: Blood
Title: Basal and angiopoietin-1-mediated endothelial permeability is regulated by sphingosine kinase-1.
Volume: 111
Issue: 7
Pages: 3489-97
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Publication
25871850 | J:232665
First Author: Wilson PC
Year: 2015
Journal: Mol Endocrinol
Title: Inhibition of Sphingosine Kinase 1 Ameliorates Angiotensin II-Induced Hypertension and Inhibits Transmembrane Calcium Entry via Store-Operated Calcium Channel.
Volume: 29
Issue: 6
Pages: 896-908
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Publication
16623665 | J:116409
First Author: Venkataraman K
Year: 2006
Journal: Biochem J
Title: Extracellular export of sphingosine kinase-1a contributes to the vascular S1P gradient.
Volume: 397
Issue: 3
Pages: 461-71
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Publication
25253697 | J:218103
First Author: Zhang W
Year: 2014
Journal: J Biol Chem
Title: Adipocyte lipolysis-stimulated interleukin-6 production requires sphingosine kinase 1 activity.
Volume: 289
Issue: 46
Pages: 32178-85
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Publication
32521763 | J:298973
 
First Author: Couttas TA
Year: 2020
Journal: Metabolites
Title: A Novel Function of Sphingosine Kinase 2 in the Metabolism of Sphinga-4,14-Diene Lipids.
Volume: 10
Issue: 6
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Publication
23766515 | J:332948
First Author: Ross JS
Year: 2013
Journal: J Biol Chem
Title: Sphingosine kinase 1 is regulated by peroxisome proliferator-activated receptor α in response to free fatty acids and is essential for skeletal muscle interleukin-6 production and signaling in diet-induced obesity.
Volume: 288
Issue: 31
Pages: 22193-206
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Publication
23839933 | J:201168
First Author: Qi Y
Year: 2013
Journal: FASEB J
Title: Loss of sphingosine kinase 1 predisposes to the onset of diabetes via promoting pancreatic β-cell death in diet-induced obese mice.
Volume: 27
Issue: 10
Pages: 4294-304
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Publication
24473437 | J:212300
First Author: Wang J
Year: 2014
Journal: Am J Physiol Endocrinol Metab
Title: Sphingosine kinase 1 regulates adipose proinflammatory responses and insulin resistance.
Volume: 306
Issue: 7
Pages: E756-68
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Publication
20962114 | J:167574
First Author: Kim M
Year: 2011
Journal: Am J Physiol Renal Physiol
Title: Isoflurane activates intestinal sphingosine kinase to protect against bilateral nephrectomy-induced liver and intestine dysfunction.
Volume: 300
Issue: 1
Pages: F167-76
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Publication
16876794 | J:112152
First Author: Michaud J
Year: 2006
Journal: FEBS Lett
Title: Normal acute and chronic inflammatory responses in sphingosine kinase 1 knockout mice.
Volume: 580
Issue: 19
Pages: 4607-12
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Publication
22355325 | J:185227
First Author: Bachmaier K
Year: 2012
Journal: PLoS One
Title: Sphingosine kinase 1 mediation of expression of the anaphylatoxin receptor C5L2 dampens the inflammatory response to endotoxin.
Volume: 7
Issue: 2
Pages: e30742
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Publication
28583134 | J:278376
First Author: Furuya H
Year: 2017
Journal: J Transl Med
Title: Sphingosine kinase 1 expression enhances colon tumor growth.
Volume: 15
Issue: 1
Pages: 120
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Publication
26240153 | J:225793
First Author: Qi Y
Year: 2015
Journal: J Biol Chem
Title: Sphingosine Kinase 1 Protects Hepatocytes from Lipotoxicity via Down-regulation of IRE1α Protein Expression.
Volume: 290
Issue: 38
Pages: 23282-90
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Publication
17898040 | J:127525
First Author: Kim M
Year: 2007
Journal: Am J Physiol Renal Physiol
Title: Isoflurane mediates protection from renal ischemia-reperfusion injury via sphingosine kinase and sphingosine-1-phosphate-dependent pathways.
Volume: 293
Issue: 6
Pages: F1827-35
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Publication
28174291 | J:246080
First Author: Rojas-Canales D
Year: 2017
Journal: Diabetes
Title: Local Sphingosine Kinase 1 Activity Improves Islet Transplantation.
Volume: 66
Issue: 5
Pages: 1301-1311
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Publication
18849324 | J:155279
First Author: Tauseef M
Year: 2008
Journal: Circ Res
Title: Activation of sphingosine kinase-1 reverses the increase in lung vascular permeability through sphingosine-1-phosphate receptor signaling in endothelial cells.
Volume: 103
Issue: 10
Pages: 1164-72
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Publication
36139489 | J:361173
 
First Author: Wilkerson JL
Year: 2022
Journal: Cells
Title: Ablation of Sphingosine Kinase 1 Protects Cornea from Neovascularization in a Mouse Corneal Injury Model.
Volume: 11
Issue: 18
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Publication
20950672 | J:170169
First Author: Kanno T
Year: 2010
Journal: Neuroscience
Title: Regulation of synaptic strength by sphingosine 1-phosphate in the hippocampus.
Volume: 171
Issue: 4
Pages: 973-80
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Publication
29028945 | J:251924
First Author: Furuya H
Year: 2017
Journal: Carcinogenesis
Title: Sphingosine Kinase 1 expression in peritoneal macrophages is required for colon carcinogenesis.
Volume: 38
Issue: 12
Pages: 1218-1227
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Publication
27050145 | J:250074
First Author: Bao Y
Year: 2016
Journal: Oncotarget
Title: Tumor suppressor PRSS8 targets Sphk1/S1P/Stat3/Akt signaling in colorectal cancer.
Volume: 7
Issue: 18
Pages: 26780-92
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Publication
19696411 | J:169965
First Author: Zhao YD
Year: 2009
Journal: Circ Res
Title: Bone marrow progenitor cells induce endothelial adherens junction integrity by sphingosine-1-phosphate-mediated Rac1 and Cdc42 signaling.
Volume: 105
Issue: 7
Pages: 696-704, 8 p following 704
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Publication
18815359 | J:146030
First Author: Snider AJ
Year: 2009
Journal: FASEB J
Title: A role for sphingosine kinase 1 in dextran sulfate sodium-induced colitis.
Volume: 23
Issue: 1
Pages: 143-52
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Publication
25231106 | J:223590
First Author: Münzer P
Year: 2014
Journal: Am J Physiol Cell Physiol
Title: Sphingosine kinase 1 (Sphk1) negatively regulates platelet activation and thrombus formation.
Volume: 307
Issue: 10
Pages: C920-7
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Publication
37751791 | J:342426
First Author: Morishige JI
Year: 2023
Journal: J Lipid Res
Title: Sphingosine kinase 1 is involved in triglyceride breakdown by maintaining lysosomal integrity in brown adipocytes.
Volume: 64
Issue: 11
Pages: 100450
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Publication
20299461 | J:163897
First Author: Di A
Year: 2010
Journal: J Biol Chem
Title: A novel function of sphingosine kinase 1 suppression of JNK activity in preventing inflammation and injury.
Volume: 285
Issue: 21
Pages: 15848-57
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Publication
29572892 | J:273930
First Author: Lan T
Year: 2018
Journal: Hepatology
Title: Sphingosine kinase 1 promotes liver fibrosis by preventing miR-19b-3p-mediated inhibition of CCR2.
Volume: 68
Issue: 3
Pages: 1070-1086
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Publication
19109558 | J:145996
First Author: Bonder CS
Year: 2009
Journal: Blood
Title: Sphingosine kinase regulates the rate of endothelial progenitor cell differentiation.
Volume: 113
Issue: 9
Pages: 2108-17
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Publication
26482537 | J:227706
First Author: Geng T
Year: 2015
Journal: J Lipid Res
Title: SphK1 mediates hepatic inflammation in a mouse model of NASH induced by high saturated fat feeding and initiates proinflammatory signaling in hepatocytes.
Volume: 56
Issue: 12
Pages: 2359-71
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Publication
26615875 | J:251426
First Author: Chen J
Year: 2016
Journal: Biochim Biophys Acta
Title: Deletion of sphingosine kinase 1 ameliorates hepatic steatosis in diet-induced obese mice: Role of PPARγ.
Volume: 1861
Issue: 2
Pages: 138-147
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Publication
24837436 | J:213222
First Author: Zhang Y
Year: 2014
Journal: J Clin Invest
Title: Elevated sphingosine-1-phosphate promotes sickling and sickle cell disease progression.
Volume: 124
Issue: 6
Pages: 2750-61
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Publication
9584134 | J:123134
First Author: Adler AJ
Year: 1998
Journal: J Exp Med
Title: CD4+ T cell tolerance to parenchymal self-antigens requires presentation by bone marrow-derived antigen-presenting cells.
Volume: 187
Issue: 10
Pages: 1555-64
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Allele
Tg(CAG-EGFP)50Osb | MGI:3760429
Name: transgene insertion 50, Research Institute for Microbial Diseases, Osaka University
Allele Type: Transgenic
Attribute String: Reporter
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Allele
Tg(tetO-lacZ,-GFP/Gria2)1Rsp | MGI:5708835
Name: transgene insertion 1, Rolf Sprengel
Allele Type: Transgenic
Attribute String: Inducible, Inserted expressed sequence, Reporter
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Allele
Tg(tetO-lacZ,-GFP/Gria2)6Rsp | MGI:5708839
Name: transgene insertion 6, Rolf Sprengel
Allele Type: Transgenic
Attribute String: Inducible, Inserted expressed sequence, Reporter
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Allele
Tg(PMP22)C22Fbas | MGI:5817407
Name: transgene insertion C22, Frank Baas
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Strain
MGI:5824744 | B6.Cg-Tg(PMP22)C22Fbas
Attribute String: transgenic, mutant strain, congenic
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Allele
Tg(PMP22)C3Fbas | MGI:5817396
Name: transgene insertion C3, Frank Baas
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Genotype
Genotype
Symbol: C3/C3
Background: D1.129P2-C3
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Sphk1/Sphk1
Background: involves: 129S6/SvEvTac * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: C3/C3
Background: B6.129S4-C3
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: C3/C3
Background: B6;129S4-C3/J
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: C3/C3
Background: involves: 129S4/SvJae
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(C3-1-TAg)cJeg/?
Background: involves: FVB/N
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(C3-1-TAg)cJeg/?
Background: FVB/N-Tg(C3-1-TAg)cJeg
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Sphk1/Sphk1
Background: involves: 129S6/SvEvTac
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(PMP22)C22Fbas/?
Background: B6.Cg-Tg(PMP22)C22Fbas
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cfi/Cfi
Background: involves: C57BL/6J
Zygosity: hm
Has Mutant Allele: true
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GO Term
GO:0009853 | photorespiration
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Strain
MGI:6352490 | C57BL/6JGpt
Attribute String: inbred strain
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Publication
7691944 | J:14834
First Author: Li B
Year: 1993
Journal: J Immunol
Title: Mouse Crry/p65. Characterization of monoclonal antibodies and the tissue distribution of a functional homologue of human MCP and DAF.
Volume: 151
Issue: 8
Pages: 4295-305
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Publication
16444293 | J:105466
First Author: Thurman JM
Year: 2006
Journal: J Clin Invest
Title: Altered renal tubular expression of the complement inhibitor Crry permits complement activation after ischemia/reperfusion.
Volume: 116
Issue: 2
Pages: 357-68
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Publication
11683962 | J:72210
First Author: Lin F
Year: 2001
Journal: Immunology
Title: Tissue distribution of products of the mouse decay-accelerating factor (DAF) genes. Exploitation of a Daf1 knock-out mouse and site-specific monoclonal antibodies.
Volume: 104
Issue: 2
Pages: 215-25
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Publication
12003997 | J:76756
First Author: Lin F
Year: 2002
Journal: Lab Invest
Title: Decay-accelerating factor confers protection against complement-mediated podocyte injury in acute nephrotoxic nephritis.
Volume: 82
Issue: 5
Pages: 563-9
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Publication
12902517 | J:84814
First Author: Banda NK
Year: 2003
Journal: J Immunol
Title: Prevention of collagen-induced arthritis in mice transgenic for the complement inhibitor complement receptor 1-related gene/protein y.
Volume: 171
Issue: 4
Pages: 2109-15
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Publication
18202746 | J:131403
First Author: Rose KL
Year: 2008
Journal: J Clin Invest
Title: Factor I is required for the development of membranoproliferative glomerulonephritis in factor H-deficient mice.
Volume: 118
Issue: 2
Pages: 608-18
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Publication
21502512 | J:172218
First Author: Schwaeble WJ
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Targeting of mannan-binding lectin-associated serine protease-2 confers protection from myocardial and gastrointestinal ischemia/reperfusion injury.
Volume: 108
Issue: 18
Pages: 7523-8
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Publication
27084103 | J:261832
First Author: Cunningham CA
Year: 2016
Journal: J Immunol
Title: POSH Regulates CD4+ T Cell Differentiation and Survival.
Volume: 196
Issue: 10
Pages: 4003-13
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Publication
1730912 | J:1533
First Author: Molina H
Year: 1992
Journal: J Exp Med
Title: Distinct receptor and regulatory properties of recombinant mouse complement receptor 1 (CR1) and Crry, the two genetic homologues of human CR1.
Volume: 175
Issue: 1
Pages: 121-9
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Publication
11509624 | J:118725
First Author: Sogabe H
Year: 2001
Journal: J Immunol
Title: Increased susceptibility of decay-accelerating factor deficient mice to anti-glomerular basement membrane glomerulonephritis.
Volume: 167
Issue: 5
Pages: 2791-7
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Publication
27577570 | J:319222
First Author: Orsini F
Year: 2016
Journal: J Neuroinflammation
Title: Mannan binding lectin-associated serine protease-2 (MASP-2) critically contributes to post-ischemic brain injury independent of MASP-1.
Volume: 13
Issue: 1
Pages: 213
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Publication
10708573 | J:61074
First Author: Sasahara K
Year: 2000
Journal: Biochem Biophys Res Commun
Title: Molecular cloning and expression analysis of a putative nuclear protein, SR-25.
Volume: 269
Issue: 2
Pages: 444-50
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Protein
Q9JM93
Organism: Mus musculus/domesticus
Length: 229  
Fragment?: false
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Protein
D3YWC2
Organism: Mus musculus/domesticus
Length: 200  
Fragment?: false
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Protein
D3Z6F1
Organism: Mus musculus/domesticus
Length: 226  
Fragment?: true
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Protein
D3Z668
Organism: Mus musculus/domesticus
Length: 98  
Fragment?: true
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Publication
7830606 | -
 
First Author: Coutinho IB
Year: 1994
Journal: Methods Enzymol
Title: Tetraheme cytochromes.
Volume: 243
Pages: 119-40
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Publication
9293186 | -
First Author: Thöny-Meyer L
Year: 1997
Journal: Microbiol Mol Biol Rev
Title: Biogenesis of respiratory cytochromes in bacteria.
Volume: 61
Issue: 3
Pages: 337-76
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Publication
17952876 | -
First Author: Lee SC
Year: 2007
Journal: Proteomics
Title: Dominant negative Rac1 attenuates paclitaxel-induced apoptosis in human melanoma cells through upregulation of heat shock protein 27: a functional proteomic analysis.
Volume: 7
Issue: 22
Pages: 4112-22
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Publication
16377641 | -
First Author: Payandeh J
Year: 2006
Journal: J Biol Chem
Title: The crystal structure of (S)-3-O-geranylgeranylglyceryl phosphate synthase reveals an ancient fold for an ancient enzyme.
Volume: 281
Issue: 9
Pages: 6070-8
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Protein Domain
IPR026438 | GGGP_synthase_archaea
Type: Family
Description: This enzyme, known also as GGGP synthase and GGGPS, is a prenyltransferase that catalyses the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). It catalyses the stereospecific first step in the biosynthesis of the characteristic membrane diether lipids of archaea. To a much lesser extent, is also able to use heptaprenyl pyrophosphate (HepPP; 35 carbon atoms) as the prenyl donor. Interestingly, the closest homologues outside this family are not the functionally equivalent enzymes of other archaea, but rather functionally distinct bacterial enzymes [, ].
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Protein Domain
IPR019532 | Nucl_RNA-splicing_assoc_SR-25
Type: Family
Description: SR-25, otherwise known as ADP-ribosylation factor-like factor 6-interacting protein 4, is expressed in virtually all tissue types. At the N terminus there is a repeat of serine-arginine (SR repeat), and towards the middle of the protein there are clusters of both serines and of basic amino acids. The presence of many nuclear localisation signals strongly implies that this is a nuclear protein that may contribute to RNA splicing []. SR-25 is also implicated, along with heat-shock-protein-27, as a mediator in the Rac1 (GTPase ras-related C3 botulinum toxin substrate 1; also see ) signalling pathway [].
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Publication
9339368 | J:43498
First Author: Yang Z
Year: 1997
Journal: Genomics
Title: Identification, partial characterization, and genetic mapping of kinesin-like protein genes in mouse.
Volume: 45
Issue: 1
Pages: 123-31
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Publication
31217324 | J:278510
First Author: Paiano J
Year: 2019
Journal: J Immunol
Title: Follicular B2 Cell Activation and Class Switch Recombination Depend on Autocrine C3ar1/C5ar1 Signaling in B2 Cells.
Volume: 203
Issue: 2
Pages: 379-388
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HT Experiment
E-GEOD-38671 | Complement Factor H deficiency results in decreased neuroretinal expression of Cd59a in aged mice
Series Id: GSE38671
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
18424734 | J:134537
First Author: Takahashi M
Year: 2008
Journal: J Immunol
Title: Mannose-binding lectin (MBL)-associated serine protease (MASP)-1 contributes to activation of the lectin complement pathway.
Volume: 180
Issue: 9
Pages: 6132-8
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Publication
7750651 | J:25267
First Author: Horan GS
Year: 1995
Journal: Dev Biol
Title: Mutations in paralogous Hox genes result in overlapping homeotic transformations of the axial skeleton: evidence for unique and redundant function.
Volume: 169
Issue: 1
Pages: 359-72
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Publication
24868011 | J:327063
First Author: Asgari E
Year: 2014
Journal: FASEB J
Title: Mannan-binding lectin-associated serine protease 2 is critical for the development of renal ischemia reperfusion injury and mediates tissue injury in the absence of complement C4.
Volume: 28
Issue: 9
Pages: 3996-4003
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Publication
24349316 | J:209864
First Author: Ali YM
Year: 2013
Journal: PLoS One
Title: Human L-ficolin, a recognition molecule of the lectin activation pathway of complement, activates complement by binding to pneumolysin, the major toxin of Streptococcus pneumoniae.
Volume: 8
Issue: 12
Pages: e82583
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Publication
15004194 | J:88632
First Author: Yamada K
Year: 2004
Journal: J Immunol
Title: Critical protection from renal ischemia reperfusion injury by CD55 and CD59.
Volume: 172
Issue: 6
Pages: 3869-75
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Publication
17259999 | J:141594
First Author: Bao L
Year: 2007
Journal: Lab Invest
Title: Decay-accelerating factor but not CD59 limits experimental immune-complex glomerulonephritis.
Volume: 87
Issue: 4
Pages: 357-64
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Publication
24850152 | J:284557
First Author: Miao J
Year: 2014
Journal: Kidney Int
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