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Search results 1901 to 2000 out of 2041 for Ins2

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Type Details Score
Allele
Ins2<em1Smoc> | MGI:6724255
Name: insulin II; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Strain
MGI:7623404 | C57BL/6JSmoc-Ins2<em3(cre/ERT2)Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Strain
MGI:6428998 | C57BL/6JSmoc-Ins2<em4Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Allele
Ins2<tm1.1Mnt> | MGI:4361695
Name: insulin II; targeted mutation 1.1, Massimo Trucco
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Ins2<em2(dre/ERT2)Smoc> | MGI:6724254
Name: insulin II; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Inducible, Recombinase
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Strain
MGI:7718113 | C57BL/6JSmoc-Ins2<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Allele
Tg(RIP1-Tag)5Dh | MGI:2447333
Name: transgene insertion 5, Douglas Hanahan
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Rr268<em4Hino> | MGI:7339005
Name: regulatory region 268; endonuclease-mediated mutation 4, Hirofumi Noguchi
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
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Allele
Rr268<em5Hino> | MGI:7339006
Name: regulatory region 268; endonuclease-mediated mutation 5, Hirofumi Noguchi
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
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Allele
Rr268<em2Hino> | MGI:7338999
Name: regulatory region 268; endonuclease-mediated mutation 2, Hirofumi Noguchi
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
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Publication
15459006 | J:96610
First Author: Berger M
Year: 2005
Journal: Blood
Title: Regulator of G-protein signaling-5 induction in pericytes coincides with active vessel remodeling during neovascularization.
Volume: 105
Issue: 3
Pages: 1094-101
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Strain
MGI:3757665 | C3HeB/FeJ-Tg(RIP1-Tag)5Dh
Attribute String: transgenic, mutant strain, coisogenic
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Strain
MGI:3618830 | C3H/He-Tg(RIP1-Tag)5Dh/Nci
Attribute String: mutant strain, transgenic, coisogenic
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Strain
MGI:7853781 | B6.C3HeB-Tg(RIP1-Tag)5Dh/Orl
Attribute String: transgenic, mutant strain, congenic
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Publication
11857345 | J:74304
First Author: Ryschich E
Year: 2002
Journal: Int J Cancer
Title: Transformation of the microvascular system during multistage tumorigenesis.
Volume: 97
Issue: 6
Pages: 719-25
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Publication
9788621 | J:52731
First Author: Ganss R
Year: 1998
Journal: Cancer Res
Title: Tumor microenvironment can restrict the effectiveness of activated antitumor lymphocytes.
Volume: 58
Issue: 20
Pages: 4673-81
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Publication
36630914 | J:332640
First Author: Tichet M
Year: 2023
Journal: Immunity
Title: Bispecific PD1-IL2v and anti-PD-L1 break tumor immunity resistance by enhancing stem-like tumor-reactive CD8(+) T cells and reprogramming macrophages.
Volume: 56
Issue: 1
Pages: 162-179.e6
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Publication
28892469 | J:259570
First Author: Johansson-Percival A
Year: 2017
Journal: Nat Immunol
Title: De novo induction of intratumoral lymphoid structures and vessel normalization enhances immunotherapy in resistant tumors.
Volume: 18
Issue: 11
Pages: 1207-1217
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Allele
Ins2<tm1(cre/ERT2)Kcmm> | MGI:4950476
Name: insulin II; targeted mutation 1, Susumu Seino
Allele Type: Targeted
Attribute String: Inducible, Recombinase
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Allele
Rr268<em1Hino> | MGI:7338993
Name: regulatory region 268; endonuclease-mediated mutation 1, Hirofumi Noguchi
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
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Allele
Rr268<em3Hino> | MGI:7339004
Name: regulatory region 268; endonuclease-mediated mutation 3, Hirofumi Noguchi
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
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Genotype
Genotype
Symbol: Tg(RIP1-Tag)5Dh/?
Background: C3HeB/FeJ-Tg(RIP1-Tag)5Dh
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(RIP1-Tag)5Dh/?
Background: C3.Cg-Rgs5 Tg(RIP1-Tag)5Dh
Zygosity: ot
Has Mutant Allele: true
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HT Experiment
GSE134180 | TrxG complex catalytic and non-catalytic activity play distinct roles in pancreas progenitor specification and differentiation (E18.5 Dpy30deltaP pancreas)
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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Allele
Tg(Mt1a-GPHB5)1Sok | MGI:3639358
Name: transgene insertion 1, Shannon L Okada
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Ins2<tm1Mnt> | MGI:4361633
Name: insulin II; targeted mutation 1, Massimo Trucco
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Tg(Ins2-Eif2s1)3Rjk | MGI:6719213
Name: transgene insertion 3, Randal J Kaufman
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Strain
MGI:7339115 | C57BL/6J-Rr268<em1Hino>
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Allele
Tg(Ins2-HBEGF)14Rin | MGI:7509694
Name: transgene insertion 14, The Tokyo Metropolitan Institute of Medical Science
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Ins2-HBEGF)17Rin | MGI:7509696
Name: transgene insertion 17, The Tokyo Metropolitan Institute of Medical Science
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Ins2-HBEGF)33Rin | MGI:7509698
Name: transgene insertion 33, The Tokyo Metropolitan Institute of Medical Science
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Genotype
Genotype
Symbol: Ins2/Ins2
Background: Not Specified
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rr268/Rr268
Background: C57BL/6J-Rr268
Zygosity: hm
Has Mutant Allele: true
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Publication
10950864 | J:64037
First Author: Schmidt JV
Year: 2000
Journal: Genes Dev
Title: The Dlk1 and Gtl2 genes are linked and reciprocally imprinted.
Volume: 14
Issue: 16
Pages: 1997-2002
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Publication
20934404 | J:166930
First Author: da Silva Xavier G
Year: 2010
Journal: Biochem Biophys Res Commun
Title: ChREBP regulates Pdx-1 and other glucose-sensitive genes in pancreatic β-cells.
Volume: 402
Issue: 2
Pages: 252-7
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Publication
8550850 | J:80168
First Author: Onrust SV
Year: 1996
Journal: J Clin Invest
Title: Modulation of L-selectin ligand expression during an immune response accompanying tumorigenesis in transgenic mice.
Volume: 97
Issue: 1
Pages: 54-64
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Publication
15059892 | J:89138
First Author: Hager JH
Year: 2004
Journal: Cancer Res
Title: Oncogene expression and genetic background influence the frequency of DNA copy number abnormalities in mouse pancreatic islet cell carcinomas.
Volume: 64
Issue: 7
Pages: 2406-10
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Strain
MGI:3809818 | C3.Cg-Rgs5<tm1.1Rgan> Tg(RIP1-Tag)5Dh
Attribute String: congenic
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Strain
MGI:6368169 | NOD.Cg-Ins2<tm1Mnt>/J
Attribute String: targeted mutation, mutant strain, congenic
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Allele
Tg(Ins2-HBEGF)5Rin | MGI:5565217
Name: transgene insertion 5, The Tokyo Metropolitan Institute of Medical Science
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Ins2<tm1.1Jfer> | MGI:6731073
Name: insulin II; targeted mutation 1.1, Jorge Ferrer
Allele Type: Targeted
Attribute String: Humanized sequence, Reporter
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Strain
MGI:6145286 | C57BL/6J-Tg(Ins2-HBEGF)14Rin/RinRbrc
Attribute String: mutant strain, coisogenic, transgenic
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Strain
MGI:6145287 | C57BL/6J-Tg(Ins2-HBEGF)17Rin/RinRbrc
Attribute String: mutant strain, coisogenic, transgenic
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Strain
MGI:6145288 | C57BL/6J-Tg(Ins2-HBEGF)33Rin/RinRbrc
Attribute String: mutant strain, coisogenic, transgenic
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Genotype
Genotype
Symbol: Tg(Mt1a-GPHB5)1Sok/?
Background: involves: C57BL/6
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rgs5/Rgs5 Tg(RIP1-Tag)5Dh/?
Background: C3.Cg-Rgs5 Tg(RIP1-Tag)5Dh
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ins1/Ins1 Ins2/Ins2
Background: involves: 129S2/SvPas * 129S4/SvJaeSor * C57BL/6 * FVB/N
Zygosity: cx
Has Mutant Allele: true
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Allele
Ins2<Akita> | MGI:1857572
 
Name: insulin II; Akita
Allele Type: Spontaneous
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Strain
MGI:6368168 | NOD.Cg-Ins2<tm1Mnt> Ins1<tm1Jja>/J
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:5565283 | C57BL/6-Tg(Ins2-HBEGF)5Rin
Attribute String: transgenic, mutant strain, coisogenic
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Strain
MGI:6145285 | C57BL/6J-Tg(Ins2-HBEGF)5Rin/RinRbrc
Attribute String: mutant strain, coisogenic, transgenic
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Allele
Ins2<tm2.1Jfer> | MGI:6731075
Name: insulin II; targeted mutation 2.1, Jorge Ferrer
Allele Type: Targeted
Attribute String: Humanized sequence, Reporter
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Strain
MGI:7339119 | C57BL/6J-Rr266<em1Hino> Rr268<em1Hino>
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Genotype
Genotype
Symbol: Tg(Ins2-HBEGF)5Rin/?
Background: C57BL/6-Tg(Ins2-HBEGF)5Rin
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rr266/Rr266 Rr268/Rr268
Background: C57BL/6J-Rr266 Rr268
Zygosity: cx
Has Mutant Allele: true
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Publication
29103923 | J:256550
First Author: van der Meulen T
Year: 2018
Journal: Cell Metab
Title: Artemether Does Not Turn α Cells into β Cells.
Volume: 27
Issue: 1
Pages: 218-225.e4
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Publication
19380737 | J:148327
First Author: Zhang SS
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Coordinated regulation by Shp2 tyrosine phosphatase of signaling events controlling insulin biosynthesis in pancreatic beta-cells.
Volume: 106
Issue: 18
Pages: 7531-6
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Publication
16210345 | J:105176
First Author: Okada SL
Year: 2006
Journal: Mol Endocrinol
Title: A glycoprotein hormone expressed in corticotrophs exhibits unique binding properties on thyroid-stimulating hormone receptor.
Volume: 20
Issue: 2
Pages: 414-25
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Strain
MGI:3584175 | C57BL/6-Ins2<Akita>
Attribute String: coisogenic, spontaneous mutation
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Strain
MGI:6145226 | A.AKITA-Ins2<Akita>/Rbrc
Attribute String: mutant strain, congenic, spontaneous mutation
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Strain
MGI:2164426 | C3H/He-Ins2<Akita>
Attribute String: mutant strain, spontaneous mutation
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Strain
MGI:3721801 | D2.B6-Ins2<Akita>/MatbJ
Attribute String: congenic, mutant strain, spontaneous mutation
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Strain
MGI:3713268 | FVB.B6-Ins2<Akita>/MlnJ
Attribute String: congenic, mutant strain, spontaneous mutation
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Strain
MGI:3664419 | C57BL/6-Ins2<Akita>/Slc
Attribute String: coisogenic, mutant strain, spontaneous mutation
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Strain
MGI:5287487 | B6.Cg-Ins2<Akita> Ldlr<tm1Her>
Attribute String: targeted mutation, mutant strain, congenic, spontaneous mutation
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Strain
MGI:2164793 | C57BL/6-Ins2<Akita>/J
Attribute String: mutant strain, spontaneous mutation
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Strain
MGI:5512650 | C.B6N-Ins2<Akita>
Attribute String: congenic, spontaneous mutation, mutant strain
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Strain
MGI:4431364 | 129S6.B6-Ins2<Akita>/CofJ
Attribute String: spontaneous mutation, mutant strain, congenic
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Publication
18418378 | J:136259
First Author: Hamzah J
Year: 2008
Journal: Nature
Title: Vascular normalization in Rgs5-deficient tumours promotes immune destruction.
Volume: 453
Issue: 7193
Pages: 410-4
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Allele
Del(7Ins2-Tel)1Lef | MGI:3772925
Name: deletion, Chr 7, Louis Lefebvre 1
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Ins2<tm1Lef> | MGI:3833432
Name: insulin II; targeted mutation 1, Louis Lefebvre
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Genotype
Genotype
Symbol: Ins2/Ins2<+>
Background: C57BL/6-Ins2
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ins2/Ins2<+>
Background: involves: C3H * C57BL/6NJcl * C57BL/6NSlc
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ins2/Ins2
Background: C57BL/6-Ins2
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ins2/Ins2
Background: C57BL/6-Ins2/J
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ins2/Ins2<+>
Background: C57BL/6-Ins2/J
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ins2/Ins2
Background: involves: C57BL/6NSlc
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ins2/?
Background: involves: C57BL/6NSlc
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ins2/Ins2
Background: C.B6N-Ins2
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ins2/Ins2<+>
Background: C.B6N-Ins2
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ins2/Ins2<+>
Background: involves: C57BL/6NSlc
Zygosity: ht
Has Mutant Allele: true
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Publication
20802254 | J:169727
First Author: Wicksteed B
Year: 2010
Journal: Diabetes
Title: Conditional gene targeting in mouse pancreatic ß-Cells: analysis of ectopic Cre transgene expression in the brain.
Volume: 59
Issue: 12
Pages: 3090-8
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Publication
24770644 | J:208032
First Author: Hasegawa Y
Year: 2014
Journal: Exp Anim
Title: Generation and characterization of Ins1-cre-driver C57BL/6N for exclusive pancreatic beta cell-specific Cre-loxP recombination.
Volume: 63
Issue: 2
Pages: 183-91
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Publication
19358156 | J:149908
First Author: Scott GJ
Year: 2009
Journal: Genesis
Title: Abnormal glucose metabolism in heterozygous mutant mice for a type I receptor required for BMP signaling.
Volume: 47
Issue: 6
Pages: 385-91
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Publication
33071988 | J:324380
 
First Author: Singha A
Year: 2020
Journal: Front Endocrinol (Lausanne)
Title: Leptin Receptors in RIP-Cre25Mgn Neurons Mediate Anti-dyslipidemia Effects of Leptin in Insulin-Deficient Mice.
Volume: 11
Pages: 588447
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Publication
24121513 | J:204977
First Author: MacLean JA 2nd
Year: 2013
Journal: J Biol Chem
Title: The RHOX homeodomain proteins regulate the expression of insulin and other metabolic regulators in the testis.
Volume: 288
Issue: 48
Pages: 34809-25
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Publication
31340201 | J:353168
     
First Author: Scoville D
Year: 2019
Journal: J Endocrinol
Title: GLIS3 binds pancreatic beta cell regulatory regions alongside other islet transcription factors.
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Publication
20682694 | J:169341
First Author: Noso S
Year: 2010
Journal: Diabetes
Title: Insulin transactivator MafA regulates intrathymic expression of insulin and affects susceptibility to type 1 diabetes.
Volume: 59
Issue: 10
Pages: 2579-87
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Publication
23229312 | J:262265
First Author: Takeshita S
Year: 2012
Journal: Genes Genet Syst
Title: Bhlhe40, a potential diabetic modifier gene on Dbm1 locus, negatively controls myocyte fatty acid oxidation.
Volume: 87
Issue: 4
Pages: 253-64
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Publication
25355422 | J:219225
First Author: Mitchell RK
Year: 2015
Journal: Hum Mol Genet
Title: Selective disruption of Tcf7l2 in the pancreatic β cell impairs secretory function and lowers β cell mass.
Volume: 24
Issue: 5
Pages: 1390-9
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Publication
24982147 | J:212278
First Author: Fløyel T
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: CTSH regulates β-cell function and disease progression in newly diagnosed type 1 diabetes patients.
Volume: 111
Issue: 28
Pages: 10305-10
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Publication
19264802 | J:173035
First Author: Yang Y
Year: 2009
Journal: Nucleic Acids Res
Title: The Krüppel-like zinc finger protein Glis3 directly and indirectly activates insulin gene transcription.
Volume: 37
Issue: 8
Pages: 2529-38
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Publication
21127075 | J:168705
First Author: Vasanth S
Year: 2011
Journal: J Biol Chem
Title: Identification of nuclear localization, DNA binding, and transactivating mechanisms of Kruppel-like zinc finger protein Gli-similar 2 (Glis2).
Volume: 286
Issue: 6
Pages: 4749-59
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Publication
20501672 | J:162929
First Author: Chen TS
Year: 2010
Journal: Endocrinology
Title: Delineating biological pathways unique to embryonic stem cell-derived insulin-producing cell lines from their noninsulin-producing progenitor cell lines.
Volume: 151
Issue: 8
Pages: 3600-10
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Publication
26147758 | J:250856
First Author: ZeRuth GT
Year: 2015
Journal: PLoS One
Title: HECT E3 Ubiquitin Ligase Itch Functions as a Novel Negative Regulator of Gli-Similar 3 (Glis3) Transcriptional Activity.
Volume: 10
Issue: 7
Pages: e0131303
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Publication
26824049 | J:339768
 
First Author: Babad J
Year: 2016
Journal: J Diabetes Res
Title: An HLA-Transgenic Mouse Model of Type 1 Diabetes That Incorporates the Reduced but Not Abolished Thymic Insulin Expression Seen in Patients.
Volume: 2016
Pages: 7959060
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Strain
MGI:5000308 | D2.Cg-Apoe<tm1Unc> Ins2<Akita>/J
Attribute String: congenic, mutant strain, targeted mutation, spontaneous mutation
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Strain
MGI:5007923 | B6.Cg-Apoe<tm1Unc> Ins2<Akita>/J
Attribute String: congenic, mutant strain, targeted mutation, spontaneous mutation
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Strain
MGI:3713278 | B6.Cg-Ins2<Akita> Bdkrb2<tm1Jfh>/SmiJ
Attribute String: congenic, mutant strain, spontaneous mutation, targeted mutation
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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