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Search results 1901 to 2000 out of 3295 for Kras

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Type Details Score
Publication
27835580 | J:312832
First Author: Cho YH
Year: 2016
Journal: Oncotarget
Title: KY1022, a small molecule destabilizing Ras via targeting the Wnt/β-catenin pathway, inhibits development of metastatic colorectal cancer.
Volume: 7
Issue: 49
Pages: 81727-81740
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Publication
33738287 | J:314015
 
First Author: Hartmann O
Year: 2021
Journal: Front Cell Dev Biol
Title: Implementation of CRISPR/Cas9 Genome Editing to Generate Murine Lung Cancer Models That Depict the Mutational Landscape of Human Disease.
Volume: 9
Pages: 641618
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Publication
33115981 | J:320884
First Author: Lee YS
Year: 2020
Journal: Mol Cells
Title: K-Ras-Activated Cells Can Develop into Lung Tumors When Runx3-Mediated Tumor Suppressor Pathways Are Abrogated.
Volume: 43
Issue: 10
Pages: 889-897
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Publication
20673990 | J:167935
First Author: Huarte M
Year: 2010
Journal: Cell
Title: A large intergenic noncoding RNA induced by p53 mediates global gene repression in the p53 response.
Volume: 142
Issue: 3
Pages: 409-19
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Publication
10085069 | J:53886
First Author: Kim E
Year: 1999
Journal: J Biol Chem
Title: Disruption of the mouse Rce1 gene results in defective Ras processing and mislocalization of Ras within cells.
Volume: 274
Issue: 13
Pages: 8383-90
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Publication
17540175 | J:122866
First Author: Gupta S
Year: 2007
Journal: Cell
Title: Binding of ras to phosphoinositide 3-kinase p110alpha is required for ras-driven tumorigenesis in mice.
Volume: 129
Issue: 5
Pages: 957-68
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Publication
8662936 | J:33385
First Author: Hsu DK
Year: 1996
Journal: J Biol Chem
Title: Identification of a murine TEF-1-related gene expressed after mitogenic stimulation of quiescent fibroblasts and during myogenic differentiation.
Volume: 271
Issue: 23
Pages: 13786-95
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Publication
26056141 | J:227321
First Author: Xie CM
Year: 2015
Journal: J Cell Biol
Title: Erbin is a novel substrate of the Sag-βTrCP E3 ligase that regulates KrasG12D-induced skin tumorigenesis.
Volume: 209
Issue: 5
Pages: 721-37
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Publication
32179091 | J:348824
First Author: Ma Y
Year: 2020
Journal: Gastroenterology
Title: Combination of PD-1 Inhibitor and OX40 Agonist Induces Tumor Rejection and Immune Memory in Mouse Models of Pancreatic Cancer.
Volume: 159
Issue: 1
Pages: 306-319.e12
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Publication
25923988 | J:222778
 
First Author: Satpathy SR
Year: 2015
Journal: Nat Commun
Title: Crystalline silica-induced leukotriene B4-dependent inflammation promotes lung tumour growth.
Volume: 6
Pages: 7064
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Publication
34525350 | J:358556
First Author: Floerchinger A
Year: 2021
Journal: Cell Rep
Title: Optimizing metastatic-cascade-dependent Rac1 targeting in breast cancer: Guidance using optical window intravital FRET imaging.
Volume: 36
Issue: 11
Pages: 109689
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Publication
32795414 | J:360185
First Author: Hoshino A
Year: 2020
Journal: Cell
Title: Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers.
Volume: 182
Issue: 4
Pages: 1044-1061.e18
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Publication
35479410 | J:332306
First Author: Nayak D
Year: 2022
Journal: iScience
Title: EMT alterations in the solute carrier landscape uncover SLC22A10/A15 imposed vulnerabilities in pancreatic cancer.
Volume: 25
Issue: 5
Pages: 104193
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Publication
28358093 | J:243860
First Author: de Sousa e Melo F
Year: 2017
Journal: Nature
Title: A distinct role for Lgr5+ stem cells in primary and metastatic colon cancer.
Volume: 543
Issue: 7647
Pages: 676-680
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Publication
33087710 | J:296850
First Author: Cho YH
Year: 2020
Journal: Nat Commun
Title: 5-FU promotes stemness of colorectal cancer via p53-mediated WNT/β-catenin pathway activation.
Volume: 11
Issue: 1
Pages: 5321
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Publication
24667486 | J:210473
 
First Author: Enquist IB
Year: 2014
Journal: Nat Commun
Title: Lymph node-independent liver metastasis in a model of metastatic colorectal cancer.
Volume: 5
Pages: 3530
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Publication
11323676 | J:68981
First Author: Johnson L
Year: 2001
Journal: Nature
Title: Somatic activation of the K-ras oncogene causes early onset lung cancer in mice.
Volume: 410
Issue: 6832
Pages: 1111-6
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31685988 | J:282941
First Author: Schmidt S
Year: 2019
Journal: Nat Cell Biol
Title: A MYC-GCN2-eIF2α negative feedback loop limits protein synthesis to prevent MYC-dependent apoptosis in colorectal cancer.
Volume: 21
Issue: 11
Pages: 1413-1424
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33239430 | J:303980
First Author: Shen M
Year: 2021
Journal: Cancer Res
Title: Therapeutic Targeting of Metadherin Suppresses Colorectal and Lung Cancer Progression and Metastasis.
Volume: 81
Issue: 4
Pages: 1014-1025
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Publication
34895463 | J:316407
   
First Author: Knight JR
Year: 2021
Journal: Elife
Title: Rpl24Bst mutation suppresses colorectal cancer by promoting eEF2 phosphorylation via eEF2K.
Volume: 10
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Publication
36208623 | J:336854
First Author: Huang Q
Year: 2022
Journal: Cell
Title: The primordial differentiation of tumor-specific memory CD8(+) T cells as bona fide responders to PD-1/PD-L1 blockade in draining lymph nodes.
Volume: 185
Issue: 22
Pages: 4049-4066.e25
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Publication
26479921 | J:228885
First Author: Alam MS
Year: 2015
Journal: Nat Med
Title: Selective inhibition of the p38 alternative activation pathway in infiltrating T cells inhibits pancreatic cancer progression.
Volume: 21
Issue: 11
Pages: 1337-43
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Publication
19208810 | J:146442
First Author: Khasawneh J
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Inflammation and mitochondrial fatty acid beta-oxidation link obesity to early tumor promotion.
Volume: 106
Issue: 9
Pages: 3354-9
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34035082 | J:307931
First Author: Lee CL
Year: 2021
Journal: Cancer Res
Title: Whole-Exome Sequencing of Radiation-Induced Thymic Lymphoma in Mouse Models Identifies Notch1 Activation as a Driver of p53 Wild-Type Lymphoma.
Volume: 81
Issue: 14
Pages: 3777-3790
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Publication
21098704 | J:166996
First Author: Gilad O
Year: 2010
Journal: Cancer Res
Title: Combining ATR suppression with oncogenic Ras synergistically increases genomic instability, causing synthetic lethality or tumorigenesis in a dosage-dependent manner.
Volume: 70
Issue: 23
Pages: 9693-702
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Publication
30914430 | J:276330
First Author: Aryal NK
Year: 2019
Journal: Cancer Res
Title: Dicer1 Phosphomimetic Promotes Tumor Progression and Dissemination.
Volume: 79
Issue: 10
Pages: 2662-2668
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Publication
16023597 | J:99695
First Author: Loeb KR
Year: 2005
Journal: Cancer Cell
Title: A mouse model for cyclin E-dependent genetic instability and tumorigenesis.
Volume: 8
Issue: 1
Pages: 35-47
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Publication
30696657 | J:274186
First Author: Bastea LI
Year: 2019
Journal: Cancer Res
Title: Pomalidomide Alters Pancreatic Macrophage Populations to Generate an Immune-Responsive Environment at Precancerous and Cancerous Lesions.
Volume: 79
Issue: 7
Pages: 1535-1548
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Publication
21907929 | J:175966
First Author: De Raedt T
Year: 2011
Journal: Cancer Cell
Title: Exploiting cancer cell vulnerabilities to develop a combination therapy for ras-driven tumors.
Volume: 20
Issue: 3
Pages: 400-13
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Publication
23873029 | J:212617
First Author: Tan EH
Year: 2014
Journal: Oncogene
Title: Functions of TAp63 and p53 in restraining the development of metastatic cancer.
Volume: 33
Issue: 25
Pages: 3325-33
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Publication
11751631 | J:73468
First Author: Fisher GH
Year: 2001
Journal: Genes Dev
Title: Induction and apoptotic regression of lung adenocarcinomas by regulation of a K-Ras transgene in the presence and absence of tumor suppressor genes.
Volume: 15
Issue: 24
Pages: 3249-62
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Publication
25586376 | J:219268
First Author: Singh SK
Year: 2015
Journal: EMBO J
Title: Antithetical NFATc1-Sox2 and p53-miR200 signaling networks govern pancreatic cancer cell plasticity.
Volume: 34
Issue: 4
Pages: 517-30
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Publication
21983037 | J:178850
First Author: Suh YA
Year: 2011
Journal: Cancer Res
Title: Multiple stress signals activate mutant p53 in vivo.
Volume: 71
Issue: 23
Pages: 7168-75
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Publication
27925213 | J:241797
First Author: Xiong S
Year: 2017
Journal: J Pathol
Title: The p53 inhibitor Mdm4 cooperates with multiple genetic lesions in tumourigenesis.
Volume: 241
Issue: 4
Pages: 501-510
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Publication
23481268 | J:243761
First Author: Kwon MC
Year: 2013
Journal: Mol Oncol
Title: Mouse models for lung cancer.
Volume: 7
Issue: 2
Pages: 165-77
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28007785 | J:237913
First Author: Brichkina A
Year: 2016
Journal: Genes Dev
Title: p38MAPK builds a hyaluronan cancer niche to drive lung tumorigenesis.
Volume: 30
Issue: 23
Pages: 2623-2636
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Publication
37345534 | J:338197
     
First Author: Nakamura T
Year: 2023
Journal: J Pathol
Title: ELF3 suppresses gallbladder cancer development through downregulation of the EREG/EGFR/mTOR complex 1 signalling pathway.
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Publication
29533781 | J:258616
First Author: Morita M
Year: 2018
Journal: Cancer Cell
Title: PKM1 Confers Metabolic Advantages and Promotes Cell-Autonomous Tumor Cell Growth.
Volume: 33
Issue: 3
Pages: 355-367.e7
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Publication
37802055 | J:342146
First Author: Rajbhandari N
Year: 2023
Journal: Cancer Cell
Title: Single-cell mapping identifies MSI(+) cells as a common origin for diverse subtypes of pancreatic cancer.
Volume: 41
Issue: 11
Pages: 1989-2005.e9
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Publication
34388391 | J:316758
First Author: Koikawa K
Year: 2021
Journal: Cell
Title: Targeting Pin1 renders pancreatic cancer eradicable by synergizing with immunochemotherapy.
Volume: 184
Issue: 18
Pages: 4753-4771.e27
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Publication
23333075 | J:193393
First Author: Cortez-Retamozo V
Year: 2013
Journal: Immunity
Title: Angiotensin II drives the production of tumor-promoting macrophages.
Volume: 38
Issue: 2
Pages: 296-308
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Publication
27265504 | J:232333
First Author: Steele CW
Year: 2016
Journal: Cancer Cell
Title: CXCR2 Inhibition Profoundly Suppresses Metastases and Augments Immunotherapy in Pancreatic Ductal Adenocarcinoma.
Volume: 29
Issue: 6
Pages: 832-845
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Publication
24260500 | J:206730
First Author: Tan X
Year: 2013
Journal: PLoS One
Title: Loss of p53 attenuates the contribution of IL-6 deletion on suppressed tumor progression and extended survival in Kras-driven murine lung cancer.
Volume: 8
Issue: 11
Pages: e80885
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Publication
26122841 | J:225594
First Author: Qu Z
Year: 2015
Journal: Cancer Res
Title: Interleukin-6 Prevents the Initiation but Enhances the Progression of Lung Cancer.
Volume: 75
Issue: 16
Pages: 3209-15
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Publication
30926808 | J:273330
First Author: Barilla RM
Year: 2019
Journal: Nat Commun
Title: Specialized dendritic cells induce tumor-promoting IL-10+IL-17+ FoxP3neg regulatory CD4+ T cells in pancreatic carcinoma.
Volume: 10
Issue: 1
Pages: 1424
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Publication
9334313 | J:43433
First Author: Johnson L
Year: 1997
Journal: Genes Dev
Title: K-ras is an essential gene in the mouse with partial functional overlap with N-ras.
Volume: 11
Issue: 19
Pages: 2468-81
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26716510 | J:306215
First Author: Benitz S
Year: 2016
Journal: Oncotarget
Title: Polycomb repressor complex 1 promotes gene silencing through H2AK119 mono-ubiquitination in acinar-to-ductal metaplasia and pancreatic cancer cells.
Volume: 7
Issue: 10
Pages: 11424-33
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Publication
39005053 | J:357275
First Author: Neuß T
Year: 2024
Journal: Cancer Res
Title: Metabolic Reprogramming Is an Initial Step in Pancreatic Carcinogenesis That Can Be Targeted to Inhibit Acinar-to-Ductal Metaplasia.
Volume: 84
Issue: 14
Pages: 2297-2312
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11793011 | J:74257
First Author: Costa RM
Year: 2002
Journal: Nature
Title: Mechanism for the learning deficits in a mouse model of neurofibromatosis type 1.
Volume: 415
Issue: 6871
Pages: 526-30
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31183403 | J:288756
First Author: Hari P
Year: 2019
Journal: Sci Adv
Title: The innate immune sensor Toll-like receptor 2 controls the senescence-associated secretory phenotype.
Volume: 5
Issue: 6
Pages: eaaw0254
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Publication
22738914 | J:191028
First Author: Lampson BL
Year: 2012
Journal: Cancer Res
Title: Targeting eNOS in pancreatic cancer.
Volume: 72
Issue: 17
Pages: 4472-82
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Publication
23066040 | J:193639
First Author: Chan IS
Year: 2012
Journal: Cancer Res
Title: Paracrine Hedgehog signaling drives metabolic changes in hepatocellular carcinoma.
Volume: 72
Issue: 24
Pages: 6344-50
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Publication
28808255 | J:250841
First Author: Zaytouni T
Year: 2017
Journal: Nat Commun
Title: Critical role for arginase 2 in obesity-associated pancreatic cancer.
Volume: 8
Issue: 1
Pages: 242
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Publication
34632444 | J:360726
 
First Author: Fitzgerald B
Year: 2021
Journal: Cell Rep Methods
Title: A mouse model for the study of anti-tumor T cell responses in Kras-driven lung adenocarcinoma.
Volume: 1
Issue: 5
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Publication
35660135 | J:358558
First Author: Kurz E
Year: 2022
Journal: Cancer Cell
Title: Exercise-induced engagement of the IL-15/IL-15Rα axis promotes anti-tumor immunity in pancreatic cancer.
Volume: 40
Issue: 7
Pages: 720-737.e5
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Publication
16267007 | J:102692
First Author: Dasgupta B
Year: 2005
Journal: Cancer Res
Title: Cerebrospinal fluid proteomic analysis reveals dysregulation of methionine aminopeptidase-2 expression in human and mouse neurofibromatosis 1-associated glioma.
Volume: 65
Issue: 21
Pages: 9843-50
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Publication
25070947 | J:216219
First Author: Anastasaki C
Year: 2014
Journal: Hum Mol Genet
Title: Neuronal NF1/RAS regulation of cyclic AMP requires atypical PKC activation.
Volume: 23
Issue: 25
Pages: 6712-21
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29533787 | J:258620
First Author: Andricovich J
Year: 2018
Journal: Cancer Cell
Title: Loss of KDM6A Activates Super-Enhancers to Induce Gender-Specific Squamous-like Pancreatic Cancer and Confers Sensitivity to BET Inhibitors.
Volume: 33
Issue: 3
Pages: 512-526.e8
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19846776 | J:154673
First Author: Gregorian C
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: PTEN dosage is essential for neurofibroma development and malignant transformation.
Volume: 106
Issue: 46
Pages: 19479-84
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17348023 | J:156097
First Author: Su W
Year: 2007
Journal: Glia
Title: Mice with GFAP-targeted loss of neurofibromin demonstrate increased axonal MET expression with aging.
Volume: 55
Issue: 7
Pages: 723-33
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18697930 | J:139699
First Author: Dovey JS
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Bmi1 is critical for lung tumorigenesis and bronchioalveolar stem cell expansion.
Volume: 105
Issue: 33
Pages: 11857-62
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18059342 | J:135610
First Author: Nakamura K
Year: 2008
Journal: Oncogene
Title: Partial functional overlap of the three ras genes in mouse embryonic development.
Volume: 27
Issue: 21
Pages: 2961-8
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28790031 | J:245611
First Author: Chiou SH
Year: 2017
Journal: Cancer Discov
Title: BLIMP1 Induces Transient Metastatic Heterogeneity in Pancreatic Cancer.
Volume: 7
Issue: 10
Pages: 1184-1199
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20505730 | J:161953
First Author: Chen L
Year: 2010
Journal: Nature
Title: CD95 promotes tumour growth.
Volume: 465
Issue: 7297
Pages: 492-6
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19841240 | J:154046
First Author: Budiu RA
Year: 2009
Journal: Dis Model Mech
Title: A conditional mouse model for human MUC1-positive endometriosis shows the presence of anti-MUC1 antibodies and Foxp3+ regulatory T cells.
Volume: 2
Issue: 11-12
Pages: 593-603
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24239348 | J:203686
First Author: Morandell S
Year: 2013
Journal: Cell Rep
Title: A reversible gene-targeting strategy identifies synthetic lethal interactions between MK2 and p53 in the DNA damage response in vivo.
Volume: 5
Issue: 4
Pages: 868-77
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19010921 | J:141383
First Author: Cheung AF
Year: 2008
Journal: Cancer Res
Title: Regulated expression of a tumor-associated antigen reveals multiple levels of T-cell tolerance in a mouse model of lung cancer.
Volume: 68
Issue: 22
Pages: 9459-68
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22411819 | J:182218
First Author: Xu X
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Evidence for type II cells as cells of origin of K-Ras-induced distal lung adenocarcinoma.
Volume: 109
Issue: 13
Pages: 4910-5
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20308544 | J:158937
First Author: Liu M
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Targeting the protein prenyltransferases efficiently reduces tumor development in mice with K-RAS-induced lung cancer.
Volume: 107
Issue: 14
Pages: 6471-6
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Publication
38733589 | J:348743
First Author: Tomić G
Year: 2024
Journal: Cell Rep
Title: Palmitoyl transferase ZDHHC20 promotes pancreatic cancer metastasis.
Volume: 43
Issue: 5
Pages: 114224
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24239359 | J:205518
First Author: Blum JM
Year: 2013
Journal: Cell Rep
Title: Distinct and overlapping sarcoma subtypes initiated from muscle stem and progenitor cells.
Volume: 5
Issue: 4
Pages: 933-40
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20697345 | J:164588
First Author: Monahan KB
Year: 2010
Journal: Oncogene
Title: Somatic p16(INK4a) loss accelerates melanomagenesis.
Volume: 29
Issue: 43
Pages: 5809-17
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23565506 | J:195492
 
First Author: Perez BA
Year: 2013
Journal: Front Oncol
Title: Assessing the radiation response of lung cancer with different gene mutations using genetically engineered mice.
Volume: 3
Pages: 72
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19151761 | J:147590
First Author: Ho VM
Year: 2009
Journal: Oncogene
Title: The retinoblastoma gene Rb and its family member p130 suppress lung adenocarcinoma induced by oncogenic K-Ras.
Volume: 28
Issue: 10
Pages: 1393-9
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18621715 | J:140423
First Author: Seidler B
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: A Cre-loxP-based mouse model for conditional somatic gene expression and knockdown in vivo by using avian retroviral vectors.
Volume: 105
Issue: 29
Pages: 10137-42
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Publication
20141835 | J:161180
First Author: Heidorn SJ
Year: 2010
Journal: Cell
Title: Kinase-dead BRAF and oncogenic RAS cooperate to drive tumor progression through CRAF.
Volume: 140
Issue: 2
Pages: 209-21
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21056012 | J:166678
First Author: Skoulidis F
Year: 2010
Journal: Cancer Cell
Title: Germline Brca2 heterozygosity promotes Kras(G12D) -driven carcinogenesis in a murine model of familial pancreatic cancer.
Volume: 18
Issue: 5
Pages: 499-509
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Publication
21368895 | J:234236
 
First Author: Ahmad I
Year: 2011
Journal: Cell Death Dis
Title: Ras mutation cooperates with β-catenin activation to drive bladder tumourigenesis.
Volume: 2
Pages: e124
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18281487 | J:131721
First Author: Iwanaga K
Year: 2008
Journal: Cancer Res
Title: Pten inactivation accelerates oncogenic K-ras-initiated tumorigenesis in a mouse model of lung cancer.
Volume: 68
Issue: 4
Pages: 1119-27
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Publication
31378680 | J:278962
First Author: Yin N
Year: 2019
Journal: Cancer Cell
Title: Protein Kinase Cι and Wnt/β-Catenin Signaling: Alternative Pathways to Kras/Trp53-Driven Lung Adenocarcinoma.
Volume: 36
Issue: 2
Pages: 156-167.e7
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19841536 | J:154600
First Author: Bornstein S
Year: 2009
Journal: J Clin Invest
Title: Smad4 loss in mice causes spontaneous head and neck cancer with increased genomic instability and inflammation.
Volume: 119
Issue: 11
Pages: 3408-19
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Publication
37803016 | J:354092
First Author: Kojima Y
Year: 2023
Journal: Nat Commun
Title: Decreased liver B vitamin-related enzymes as a metabolic hallmark of cancer cachexia.
Volume: 14
Issue: 1
Pages: 6246
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Publication
21169405 | J:169319
First Author: Muraguchi T
Year: 2011
Journal: Cancer Res
Title: NKX2.2 suppresses self-renewal of glioma-initiating cells.
Volume: 71
Issue: 3
Pages: 1135-45
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19603508 | J:153565
First Author: Woolfenden S
Year: 2009
Journal: Genesis
Title: A Cre/LoxP conditional luciferase reporter transgenic mouse for bioluminescence monitoring of tumorigenesis.
Volume: 47
Issue: 10
Pages: 659-66
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Publication
24535260 | J:208036
First Author: Shi C
Year: 2014
Journal: Lab Invest
Title: Fibrogenesis in pancreatic cancer is a dynamic process regulated by macrophage-stellate cell interaction.
Volume: 94
Issue: 4
Pages: 409-21
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Publication
33632774 | J:307164
     
First Author: DeStefano Shields CE
Year: 2021
Journal: Cancer Discov
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