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Search results 1901 to 2000 out of 2139 for Lck

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Type Details Score
Publication
15655112 | J:95693
First Author: Bijl J
Year: 2005
Journal: Genes Dev
Title: High incidence of proviral integrations in the Hoxa locus in a new model of E2a-PBX1-induced B-cell leukemia.
Volume: 19
Issue: 2
Pages: 224-33
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Publication
25124553 | J:230230
First Author: Kurtulus S
Year: 2015
Journal: Cell Death Differ
Title: Bim controls IL-15 availability and limits engagement of multiple BH3-only proteins.
Volume: 22
Issue: 1
Pages: 174-84
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Publication
28096407 | J:240744
First Author: Ogasawara T
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Development of chronic allergic responses by dampening Bcl6-mediated suppressor activity in memory T helper 2 cells.
Volume: 114
Issue: 5
Pages: E741-E750
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Publication
24046360 | J:202090
First Author: Carofino BL
Year: 2013
Journal: Dis Model Mech
Title: A mouse model for inducible overexpression of Prdm14 results in rapid-onset and highly penetrant T-cell acute lymphoblastic leukemia (T-ALL).
Volume: 6
Issue: 6
Pages: 1494-506
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Publication
30076146 | J:266278
First Author: Wang Q
Year: 2018
Journal: Blood
Title: Stage-specific roles for Zmiz1 in Notch-dependent steps of early T-cell development.
Volume: 132
Issue: 12
Pages: 1279-1292
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Publication
18327260 | J:133262
First Author: Oh-Hora M
Year: 2008
Journal: Nat Immunol
Title: Dual functions for the endoplasmic reticulum calcium sensors STIM1 and STIM2 in T cell activation and tolerance.
Volume: 9
Issue: 4
Pages: 432-43
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Publication
29449309 | J:261592
First Author: Guan T
Year: 2018
Journal: J Exp Med
Title: ZEB1, ZEB2, and the miR-200 family form a counterregulatory network to regulate CD8+ T cell fates.
Volume: 215
Issue: 4
Pages: 1153-1168
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Publication
31477729 | J:279305
First Author: Arina A
Year: 2019
Journal: Nat Commun
Title: Tumor-reprogrammed resident T cells resist radiation to control tumors.
Volume: 10
Issue: 1
Pages: 3959
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Publication
26214742 | J:233111
First Author: Dufner A
Year: 2015
Journal: Nat Immunol
Title: The ubiquitin-specific protease USP8 is critical for the development and homeostasis of T cells.
Volume: 16
Issue: 9
Pages: 950-60
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Publication
38765012 | J:354877
 
First Author: Potter SJ
Year: 2024
Journal: Front Immunol
Title: KMT2D regulates activation, localization, and integrin expression by T-cells.
Volume: 15
Pages: 1341745
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Publication
18974357 | J:140630
First Author: Jin J
Year: 2008
Journal: Science
Title: Deletion of Trpm7 disrupts embryonic development and thymopoiesis without altering Mg2+ homeostasis.
Volume: 322
Issue: 5902
Pages: 756-60
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Publication
28889989 | J:255247
First Author: Vasanthakumar A
Year: 2017
Journal: Cell Rep
Title: The TNF Receptor Superfamily-NF-κB Axis Is Critical to Maintain Effector Regulatory T Cells in Lymphoid and Non-lymphoid Tissues.
Volume: 20
Issue: 12
Pages: 2906-2920
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Publication
30917317 | J:283095
First Author: Taves MD
Year: 2019
Journal: Cell Rep
Title: Single-Cell Resolution and Quantitation of Targeted Glucocorticoid Delivery in the Thymus.
Volume: 26
Issue: 13
Pages: 3629-3642.e4
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Publication
- | J:303166
 
First Author: Vacaresse N
Year: 2021
Journal: Open Journal of Immunology
Title: The Glycosylphosphatidylinositol Anchor Regulates T Cell Antigen Receptor Induced IL-2 Production
Volume: 11
Pages: 1-24
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Publication
37307442 | J:353946
First Author: Nguyen TTT
Year: 2023
Journal: Proc Natl Acad Sci U S A
Title: Stimulation of ectopically expressed muscarinic receptors induces IFN-γ but suppresses IL-2 production by inhibiting activation of pAKT pathways in primary T cells.
Volume: 120
Issue: 25
Pages: e2300987120
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Publication
24723679 | J:213132
First Author: Masson F
Year: 2014
Journal: Blood
Title: Id2 represses E2A-mediated activation of IL-10 expression in T cells.
Volume: 123
Issue: 22
Pages: 3420-8
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Publication
35243213 | J:321526
First Author: Sibilio A
Year: 2022
Journal: iScience
Title: Immune translational control by CPEB4 regulates intestinal inflammation resolution and colorectal cancer development.
Volume: 25
Issue: 2
Pages: 103790
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Publication
19454673 | J:148866
First Author: Papadaki O
Year: 2009
Journal: J Immunol
Title: Control of thymic T cell maturation, deletion and egress by the RNA-binding protein HuR.
Volume: 182
Issue: 11
Pages: 6779-88
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Publication
14499113 | J:85810
First Author: Schmidt-Supprian M
Year: 2003
Journal: Immunity
Title: Mature T cells depend on signaling through the IKK complex.
Volume: 19
Issue: 3
Pages: 377-89
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Publication
35294890 | J:324845
First Author: Fernández-Pisonero I
Year: 2022
Journal: Cell Rep
Title: A hotspot mutation targeting the R-RAS2 GTPase acts as a potent oncogenic driver in a wide spectrum of tumors.
Volume: 38
Issue: 11
Pages: 110522
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Publication
34266888 | J:321473
First Author: Trakala M
Year: 2021
Journal: Genes Dev
Title: Clonal selection of stable aneuploidies in progenitor cells drives high-prevalence tumorigenesis.
Volume: 35
Issue: 15-16
Pages: 1079-1092
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Publication
39723889 | J:361017
First Author: Osum KC
Year: 2025
Journal: Cell Rep
Title: A minority of Th1 and Tfh effector cells express survival genes shared by memory cell progeny that require IL-7 or TCR signaling to persist.
Volume: 44
Issue: 1
Pages: 115111
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Publication
22425248 | J:187335
First Author: Rao RR
Year: 2012
Journal: Immunity
Title: Transcription factor Foxo1 represses T-bet-mediated effector functions and promotes memory CD8(+) T cell differentiation.
Volume: 36
Issue: 3
Pages: 374-87
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Publication
15792999 | J:97416
First Author: Bezbradica JS
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Commitment toward the natural T (iNKT) cell lineage occurs at the CD4+8+ stage of thymic ontogeny.
Volume: 102
Issue: 14
Pages: 5114-9
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Publication
37392736 | J:338301
First Author: Evrard M
Year: 2023
Journal: Immunity
Title: Single-cell protein expression profiling resolves circulating and resident memory T cell diversity across tissues and infection contexts.
Volume: 56
Issue: 7
Pages: 1664-1680.e9
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Publication
39406245 | J:358145
First Author: Obers A
Year: 2024
Journal: Immunity
Title: Retinoic acid and TGF-β orchestrate organ-specific programs of tissue residency.
Volume: 57
Issue: 11
Pages: 2615-2633.e10
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Publication
22984076 | J:190653
First Author: Chou CK
Year: 2012
Journal: J Immunol
Title: Cell-intrinsic abrogation of TGF-β signaling delays but does not prevent dysfunction of self/tumor-specific CD8 T cells in a murine model of autochthonous prostate cancer.
Volume: 189
Issue: 8
Pages: 3936-46
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Publication
32268106 | J:303488
First Author: Wu J
Year: 2020
Journal: Cell Rep
Title: T Cell Factor 1 Suppresses CD103+ Lung Tissue-Resident Memory T Cell Development.
Volume: 31
Issue: 1
Pages: 107484
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Publication
25706747 | J:231497
First Author: Bergsbaken T
Year: 2015
Journal: Nat Immunol
Title: Proinflammatory microenvironments within the intestine regulate the differentiation of tissue-resident CD8⁺ T cells responding to infection.
Volume: 16
Issue: 4
Pages: 406-14
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Publication
24961879 | J:290002
First Author: Bauer O
Year: 2014
Journal: Cancer Prev Res (Phila)
Title: Carcinogen-induced skin tumor development requires leukocytic expression of the transcription factor Runx3.
Volume: 7
Issue: 9
Pages: 913-26
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Publication
30626694 | J:273018
First Author: Philips RL
Year: 2019
Journal: J Immunol
Title: Cutting Edge: HDAC3 Protects Double-Positive Thymocytes from P2X7 Receptor-Induced Cell Death.
Volume: 202
Issue: 4
Pages: 1033-1038
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Publication
36316474 | J:333184
First Author: Lee RD
Year: 2022
Journal: Nat Immunol
Title: Nuclear corepressors NCOR1/NCOR2 regulate B cell development, maintain genomic integrity and prevent transformation.
Volume: 23
Issue: 12
Pages: 1763-1776
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Publication
21828136 | J:178407
First Author: Berquam-Vrieze KE
Year: 2011
Journal: Blood
Title: Cell of origin strongly influences genetic selection in a mouse model of T-ALL.
Volume: 118
Issue: 17
Pages: 4646-56
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Publication
29339447 | J:257434
First Author: Xiao X
Year: 2018
Journal: J Exp Med
Title: Guidance of super-enhancers in regulation of IL-9 induction and airway inflammation.
Volume: 215
Issue: 2
Pages: 559-574
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Publication
32487999 | J:292266
First Author: Evnouchidou I
Year: 2020
Journal: Nat Commun
Title: IRAP-dependent endosomal T cell receptor signalling is essential for T cell responses.
Volume: 11
Issue: 1
Pages: 2779
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Publication
25715232 | J:333635
First Author: Salmond RJ
Year: 2015
Journal: Cell Cycle
Title: Multifunctional roles of the autoimmune disease-associated tyrosine phosphatase PTPN22 in regulating T cell homeostasis.
Volume: 14
Issue: 5
Pages: 705-11
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Publication
21411734 | J:172516
First Author: Molinero LL
Year: 2011
Journal: J Immunol
Title: High TCR stimuli prevent induced regulatory T cell differentiation in a NF-κB-dependent manner.
Volume: 186
Issue: 8
Pages: 4609-17
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Publication
22988576 | J:207361
First Author: Zhu Y
Year: 2012
Journal: Genesis
Title: Generation of Dhx9-deficient clones in T-cell development with a mitotic recombination technique.
Volume: 50
Issue: 7
Pages: 543-51
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Publication
18955569 | J:144072
First Author: Jani A
Year: 2008
Journal: J Exp Med
Title: A novel genetic strategy reveals unexpected roles of the Swi-Snf-like chromatin-remodeling BAF complex in thymocyte development.
Volume: 205
Issue: 12
Pages: 2813-25
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Publication
30374131 | J:282643
First Author: Hosokawa H
Year: 2018
Journal: Nat Immunol
Title: Bcl11b sets pro-T cell fate by site-specific cofactor recruitment and by repressing Id2 and Zbtb16.
Volume: 19
Issue: 12
Pages: 1427-1440
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Publication
33226340 | J:313472
   
First Author: Saragovi A
Year: 2020
Journal: Elife
Title: Systemic hypoxia inhibits T cell response by limiting mitobiogenesis via matrix substrate-level phosphorylation arrest.
Volume: 9
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Publication
29440508 | J:259797
First Author: Mittelstadt PR
Year: 2018
Journal: J Immunol
Title: Cutting Edge: De Novo Glucocorticoid Synthesis by Thymic Epithelial Cells Regulates Antigen-Specific Thymocyte Selection.
Volume: 200
Issue: 6
Pages: 1988-1994
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Publication
20139079 | J:161182
First Author: Yu S
Year: 2010
Journal: J Biol Chem
Title: Critical requirement of GABPalpha for normal T cell development.
Volume: 285
Issue: 14
Pages: 10179-88
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Publication
31304633 | J:299135
First Author: Vlaming H
Year: 2019
Journal: EMBO J
Title: Conserved crosstalk between histone deacetylation and H3K79 methylation generates DOT1L-dose dependency in HDAC1-deficient thymic lymphoma.
Volume: 38
Issue: 14
Pages: e101564
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Publication
20835229 | J:164684
First Author: Jacobelli J
Year: 2010
Journal: Nat Immunol
Title: Confinement-optimized three-dimensional T cell amoeboid motility is modulated via myosin IIA-regulated adhesions.
Volume: 11
Issue: 10
Pages: 953-61
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Publication
21880987 | J:179326
First Author: Menzel U
Year: 2011
Journal: J Immunol
Title: Modulation of the murine CD8 gene complex following the targeted integration of human CD2-locus control region sequences.
Volume: 187
Issue: 7
Pages: 3712-20
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Publication
34004162 | J:354460
First Author: Moreno-Fernandez ME
Year: 2021
Journal: Cell Metab
Title: PKM2-dependent metabolic skewing of hepatic Th17 cells regulates pathogenesis of non-alcoholic fatty liver disease.
Volume: 33
Issue: 6
Pages: 1187-1204.e9
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Publication
33602720 | J:352745
First Author: Veliça P
Year: 2021
Journal: Cancer Immunol Res
Title: Modified Hypoxia-Inducible Factor Expression in CD8(+) T Cells Increases Antitumor Efficacy.
Volume: 9
Issue: 4
Pages: 401-414
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Publication
32453801 | J:289643
First Author: Hantisteanu S
Year: 2020
Journal: PLoS One
Title: Runx3 prevents spontaneous colitis by directing the differentiation of anti-inflammatory mononuclear phagocytes.
Volume: 15
Issue: 5
Pages: e0233044
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Publication
11698434 | J:135121
First Author: Mora AL
Year: 2001
Journal: J Immunol
Title: Inefficient ZAP-70 phosphorylation and decreased thymic selection in vivo result from inhibition of NF-kappaB/Rel.
Volume: 167
Issue: 10
Pages: 5628-35
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Publication
32169840 | J:287487
First Author: Vongpipatana T
Year: 2020
Journal: J Immunol
Title: ADAR1 Regulates Early T Cell Development via MDA5-Dependent and -Independent Pathways.
Volume: 204
Issue: 8
Pages: 2156-2168
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Publication
21670318 | J:178037
First Author: Cantor J
Year: 2011
Journal: J Immunol
Title: Loss of T cell CD98 H chain specifically ablates T cell clonal expansion and protects from autoimmunity.
Volume: 187
Issue: 2
Pages: 851-60
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Publication
25108421 | J:259368
First Author: Salmond RJ
Year: 2014
Journal: Nat Immunol
Title: The tyrosine phosphatase PTPN22 discriminates weak self peptides from strong agonist TCR signals.
Volume: 15
Issue: 9
Pages: 875-883
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Publication
24211184 | J:208994
First Author: Yao S
Year: 2013
Journal: Immunity
Title: Interferon regulatory factor 4 sustains CD8(+) T cell expansion and effector differentiation.
Volume: 39
Issue: 5
Pages: 833-45
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26500062 | J:297037
First Author: Heltemes-Harris LM
Year: 2016
Journal: Oncogene
Title: Sleeping Beauty transposon screen identifies signaling modules that cooperate with STAT5 activation to induce B-cell acute lymphoblastic leukemia.
Volume: 35
Issue: 26
Pages: 3454-64
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Publication
28550203 | J:250655
First Author: Takahashi R
Year: 2017
Journal: J Immunol
Title: SOCS1 Is a Key Molecule That Prevents Regulatory T Cell Plasticity under Inflammatory Conditions.
Volume: 199
Issue: 1
Pages: 149-158
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Publication
25229336 | J:232457
First Author: Gerl M
Year: 2015
Journal: Kidney Int
Title: Inducible deletion of connexin 40 in adult mice causes hypertension and disrupts pressure control of renin secretion.
Volume: 87
Issue: 3
Pages: 557-63
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Publication
32716294 | J:293991
   
First Author: Umpierre AD
Year: 2020
Journal: Elife
Title: Microglial calcium signaling is attuned to neuronal activity in awake mice.
Volume: 9
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Genotype
Genotype
Symbol: Dhx9/Dhx9<+> Igs12/Igs12 Ptprc/Ptprc Tg(Lck-cre)#Zhu/?
Background: involves: 129S6/SvEvTac * C57BL/6 * FVB/NJ * SJL/J
Zygosity: cn
Has Mutant Allele: true
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Publication
18258917 | J:131081
First Author: Setoguchi R
Year: 2008
Journal: Science
Title: Repression of the transcription factor Th-POK by Runx complexes in cytotoxic T cell development.
Volume: 319
Issue: 5864
Pages: 822-5
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Publication
27102484 | J:232474
First Author: Mackay LK
Year: 2016
Journal: Science
Title: Hobit and Blimp1 instruct a universal transcriptional program of tissue residency in lymphocytes.
Volume: 352
Issue: 6284
Pages: 459-63
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18313334 | J:132877
First Author: Gardam S
Year: 2008
Journal: Immunity
Title: TRAF2 and TRAF3 signal adapters act cooperatively to control the maturation and survival signals delivered to B cells by the BAFF receptor.
Volume: 28
Issue: 3
Pages: 391-401
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18195075 | J:131287
First Author: Aliahmad P
Year: 2008
Journal: J Exp Med
Title: Development of all CD4 T lineages requires nuclear factor TOX.
Volume: 205
Issue: 1
Pages: 245-56
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Publication
12934078 | J:128143
First Author: Mora AL
Year: 2003
Journal: Cell Death Differ
Title: Antiapoptotic function of NF-kappaB in T lymphocytes is influenced by their differentiation status: roles of Fas, c-FLIP, and Bcl-xL.
Volume: 10
Issue: 9
Pages: 1032-44
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Publication
31462647 | J:279330
First Author: Sasaki K
Year: 2019
Journal: Nat Commun
Title: Modulation of autoimmune pathogenesis by T cell-triggered inflammatory cell death.
Volume: 10
Issue: 1
Pages: 3878
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Publication
20383124 | J:159461
First Author: Okamoto K
Year: 2010
Journal: Nature
Title: IkappaBzeta regulates T(H)17 development by cooperating with ROR nuclear receptors.
Volume: 464
Issue: 7293
Pages: 1381-5
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17442925 | J:135903
First Author: Mao C
Year: 2007
Journal: J Immunol
Title: Unequal contribution of Akt isoforms in the double-negative to double-positive thymocyte transition.
Volume: 178
Issue: 9
Pages: 5443-53
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Publication
24912151 | J:211624
First Author: Varanasi V
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Loss of the death receptor CD95 (Fas) expression by dendritic cells protects from a chronic viral infection.
Volume: 111
Issue: 23
Pages: 8559-64
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Publication
25821220 | J:236699
First Author: Schmidt AM
Year: 2015
Journal: J Immunol
Title: Regulatory T cells require TCR signaling for their suppressive function.
Volume: 194
Issue: 9
Pages: 4362-70
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Publication
32019420 | J:314488
First Author: Wang Z
Year: 2021
Journal: Autophagy
Title: Autophagy-based unconventional secretion of HMGB1 by keratinocytes plays a pivotal role in psoriatic skin inflammation.
Volume: 17
Issue: 2
Pages: 529-552
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Publication
28580944 | J:250341
 
First Author: McKenzie DR
Year: 2017
Journal: Nat Commun
Title: IL-17-producing γδ T cells switch migratory patterns between resting and activated states.
Volume: 8
Pages: 15632
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Publication
34035082 | J:307931
First Author: Lee CL
Year: 2021
Journal: Cancer Res
Title: Whole-Exome Sequencing of Radiation-Induced Thymic Lymphoma in Mouse Models Identifies Notch1 Activation as a Driver of p53 Wild-Type Lymphoma.
Volume: 81
Issue: 14
Pages: 3777-3790
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Publication
23410974 | J:194309
First Author: Khandanpour C
Year: 2013
Journal: Cancer Cell
Title: Growth factor independence 1 antagonizes a p53-induced DNA damage response pathway in lymphoblastic leukemia.
Volume: 23
Issue: 2
Pages: 200-14
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Publication
23791643 | J:207581
First Author: Han D
Year: 2013
Journal: Immunity
Title: Dendritic cell expression of the signaling molecule TRAF6 is critical for gut microbiota-dependent immune tolerance.
Volume: 38
Issue: 6
Pages: 1211-22
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Publication
31740486 | J:282219
First Author: Gaddis DE
Year: 2019
Journal: J Immunol
Title: Neuropilin-1 Expression on CD4 T Cells Is Atherogenic and Facilitates T Cell Migration to the Aorta in Atherosclerosis.
Volume: 203
Issue: 12
Pages: 3237-3246
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Publication
28951542 | J:254770
First Author: Kojo S
Year: 2017
Journal: Nat Commun
Title: Priming of lineage-specifying genes by Bcl11b is required for lineage choice in post-selection thymocytes.
Volume: 8
Issue: 1
Pages: 702
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Publication
23109710 | J:190889
First Author: McCaughtry TM
Year: 2012
Journal: J Exp Med
Title: Conditional deletion of cytokine receptor chains reveals that IL-7 and IL-15 specify CD8 cytotoxic lineage fate in the thymus.
Volume: 209
Issue: 12
Pages: 2263-76
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Publication
26569626 | J:321101
First Author: Jia W
Year: 2015
Journal: Autophagy
Title: Autophagy regulates T lymphocyte proliferation through selective degradation of the cell-cycle inhibitor CDKN1B/p27Kip1.
Volume: 11
Issue: 12
Pages: 2335-45
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Publication
22084093 | J:180395
First Author: Baschant U
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Glucocorticoid therapy of antigen-induced arthritis depends on the dimerized glucocorticoid receptor in T cells.
Volume: 108
Issue: 48
Pages: 19317-22
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Publication
20118929 | J:158504
First Author: Park JH
Year: 2010
Journal: Nat Immunol
Title: Signaling by intrathymic cytokines, not T cell antigen receptors, specifies CD8 lineage choice and promotes the differentiation of cytotoxic-lineage T cells.
Volume: 11
Issue: 3
Pages: 257-64
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Publication
23805138 | J:208318
 
First Author: Raynor J
Year: 2013
Journal: Front Immunol
Title: IL-15 Fosters Age-Driven Regulatory T Cell Accrual in the Face of Declining IL-2 Levels.
Volume: 4
Pages: 161
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Publication
31053612 | J:276463
First Author: Kotov JA
Year: 2019
Journal: J Exp Med
Title: BCL6 corepressor contributes to Th17 cell formation by inhibiting Th17 fate suppressors.
Volume: 216
Issue: 6
Pages: 1450-1464
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Publication
30022064 | J:265033
First Author: Zhu L
Year: 2018
Journal: Nat Commun
Title: TBK-binding protein 1 regulates IL-15-induced autophagy and NKT cell survival.
Volume: 9
Issue: 1
Pages: 2812
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Publication
30049881 | J:323810
First Author: Poffenberger MC
Year: 2018
Journal: Science
Title: LKB1 deficiency in T cells promotes the development of gastrointestinal polyposis.
Volume: 361
Issue: 6400
Pages: 406-411
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Publication
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