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Search results 1901 to 2000 out of 2308 for Lep

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Type Details Score
Publication
32879136 | J:301076
 
First Author: Li Y
Year: 2020
Journal: JCI Insight
Title: Hepatic lipids promote liver metastasis.
Volume: 5
Issue: 17
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10359811 | J:55722
First Author: Samad F
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: Tumor necrosis factor alpha is a key component in the obesity-linked elevation of plasminogen activator inhibitor 1.
Volume: 96
Issue: 12
Pages: 6902-7
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Publication
25223801 | J:220087
First Author: Hinoi E
Year: 2014
Journal: Biochem Biophys Res Commun
Title: Nuclear factor-κB is a common upstream signal for growth differentiation factor-5 expression in brown adipocytes exposed to pro-inflammatory cytokines and palmitate.
Volume: 452
Issue: 4
Pages: 974-9
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Publication
34496251 | J:327012
First Author: Bai X
Year: 2021
Journal: Cell Rep
Title: Diurnal regulation of oxidative phosphorylation restricts hepatocyte proliferation and inflammation.
Volume: 36
Issue: 10
Pages: 109659
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Publication
30893596 | J:281443
First Author: Nakatsu Y
Year: 2019
Journal: Cell Rep
Title: Prolyl Isomerase Pin1 Suppresses Thermogenic Programs in Adipocytes by Promoting Degradation of Transcriptional Co-activator PRDM16.
Volume: 26
Issue: 12
Pages: 3221-3230.e3
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Publication
31594848 | J:280606
First Author: Liu B
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Sustained ER stress promotes hyperglycemia by increasing glucagon action through the deubiquitinating enzyme USP14.
Volume: 116
Issue: 43
Pages: 21732-21738
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Publication
18645210 | J:142866
First Author: López-Parra M
Year: 2008
Journal: J Lipid Res
Title: Regulatory effects of arachidonate 5-lipoxygenase on hepatic microsomal TG transfer protein activity and VLDL-triglyceride and apoB secretion in obese mice.
Volume: 49
Issue: 12
Pages: 2513-23
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Publication
17440173 | J:126461
First Author: Hajri T
Year: 2007
Journal: Diabetes
Title: CD36-facilitated fatty acid uptake inhibits leptin production and signaling in adipose tissue.
Volume: 56
Issue: 7
Pages: 1872-80
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Publication
26644581 | J:228308
First Author: Luan B
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: CREB pathway links PGE2 signaling with macrophage polarization.
Volume: 112
Issue: 51
Pages: 15642-7
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Publication
22080103 | J:183668
First Author: Mitra R
Year: 2012
Journal: J Mol Cell Cardiol
Title: The transcriptional coactivators, PGC-1α and β, cooperate to maintain cardiac mitochondrial function during the early stages of insulin resistance.
Volume: 52
Issue: 3
Pages: 701-10
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Publication
24326453 | J:208060
First Author: Wang XQ
Year: 2014
Journal: J Invest Dermatol
Title: Ganglioside GM3 depletion reverses impaired wound healing in diabetic mice by activating IGF-1 and insulin receptors.
Volume: 134
Issue: 5
Pages: 1446-1455
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Publication
25352638 | J:247167
First Author: Barbarroja N
Year: 2015
Journal: Diabetes
Title: Increased dihydroceramide/ceramide ratio mediated by defective expression of degs1 impairs adipocyte differentiation and function.
Volume: 64
Issue: 4
Pages: 1180-92
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Publication
20616094 | J:163324
First Author: Villasenor A
Year: 2010
Journal: Dis Model Mech
Title: Rgs16 and Rgs8 in embryonic endocrine pancreas and mouse models of diabetes.
Volume: 3
Issue: 9-10
Pages: 567-80
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Publication
17575085 | J:126584
First Author: Hao M
Year: 2007
Journal: Diabetes
Title: Direct effect of cholesterol on insulin secretion: a novel mechanism for pancreatic beta-cell dysfunction.
Volume: 56
Issue: 9
Pages: 2328-38
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Publication
32375030 | J:300463
First Author: Sato H
Year: 2020
Journal: Cell Rep
Title: Secreted Phospholipase PLA2G2D Contributes to Metabolic Health by Mobilizing ω3 Polyunsaturated Fatty Acids in WAT.
Volume: 31
Issue: 5
Pages: 107579
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Publication
37245295 | J:353411
 
First Author: Akl MG
Year: 2023
Journal: Biochem Biophys Res Commun
Title: Euglycemia is affected by stress defense factor hepatocyte NRF1, but not NRF2.
Volume: 668
Pages: 96-103
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Publication
34857760 | J:317949
First Author: Lacroix M
Year: 2021
Journal: Nat Commun
Title: The multifunctional protein E4F1 links P53 to lipid metabolism in adipocytes.
Volume: 12
Issue: 1
Pages: 7037
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Publication
19435851 | J:151166
First Author: Yang G
Year: 2009
Journal: Am J Physiol Endocrinol Metab
Title: Central role of ceramide biosynthesis in body weight regulation, energy metabolism, and the metabolic syndrome.
Volume: 297
Issue: 1
Pages: E211-24
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10884431 | J:126631
First Author: Nisoli E
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: Tumor necrosis factor alpha mediates apoptosis of brown adipocytes and defective brown adipocyte function in obesity.
Volume: 97
Issue: 14
Pages: 8033-8
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Publication
26134028 | J:224384
 
First Author: Trabelsi MS
Year: 2015
Journal: Nat Commun
Title: Farnesoid X receptor inhibits glucagon-like peptide-1 production by enteroendocrine L cells.
Volume: 6
Pages: 7629
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Publication
25395617 | J:236588
First Author: Zhang J
Year: 2015
Journal: Arterioscler Thromb Vasc Biol
Title: Protein tyrosine phosphatase 1B impairs diabetic wound healing through vascular endothelial growth factor receptor 2 dephosphorylation.
Volume: 35
Issue: 1
Pages: 163-74
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Publication
34818060 | J:327731
First Author: Manigrasso MB
Year: 2021
Journal: Sci Transl Med
Title: Small-molecule antagonism of the interaction of the RAGE cytoplasmic domain with DIAPH1 reduces diabetic complications in mice.
Volume: 13
Issue: 621
Pages: eabf7084
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Publication
16436658 | J:106303
First Author: Neels JG
Year: 2006
Journal: Am J Pathol
Title: Autoamplification of tumor necrosis factor-alpha: a potential mechanism for the maintenance of elevated tumor necrosis factor-alpha in male but not female obese mice.
Volume: 168
Issue: 2
Pages: 435-44
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Publication
30376348 | J:273890
First Author: Borges BC
Year: 2019
Journal: Am J Physiol Endocrinol Metab
Title: Insulin signaling in LepR cells modulates fat and glucose homeostasis independent of leptin.
Volume: 316
Issue: 1
Pages: E121-E134
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Publication
21084751 | J:171868
First Author: Bricambert J
Year: 2010
Journal: J Clin Invest
Title: Salt-inducible kinase 2 links transcriptional coactivator p300 phosphorylation to the prevention of ChREBP-dependent hepatic steatosis in mice.
Volume: 120
Issue: 12
Pages: 4316-31
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Publication
29522093 | J:260503
First Author: Pan W
Year: 2018
Journal: Endocrinology
Title: Essential Role for Hypothalamic Calcitonin Receptor‒Expressing Neurons in the Control of Food Intake by Leptin.
Volume: 159
Issue: 4
Pages: 1860-1872
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Publication
29449623 | J:323144
First Author: Becerril S
Year: 2018
Journal: Int J Obes (Lond)
Title: Targeted disruption of the iNOS gene improves adipose tissue inflammation and fibrosis in leptin-deficient ob/ob mice: role of tenascin C.
Volume: 42
Issue: 8
Pages: 1458-1470
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Publication
28894084 | J:247623
First Author: Ichijo R
Year: 2017
Journal: Nat Commun
Title: Tbx3-dependent amplifying stem cell progeny drives interfollicular epidermal expansion during pregnancy and regeneration.
Volume: 8
Issue: 1
Pages: 508
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Publication
25307347 | J:216580
First Author: Goren I
Year: 2014
Journal: Am J Pathol
Title: Uptake of neutrophil-derived Ym1 protein distinguishes wound macrophages in the absence of interleukin-4 signaling in murine wound healing.
Volume: 184
Issue: 12
Pages: 3249-61
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Publication
29132537 | J:273108
 
First Author: Kang G
Year: 2017
Journal: Metabolism
Title: NFIL3 is a negative regulator of hepatic gluconeogenesis.
Volume: 77
Pages: 13-22
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Publication
26076035 | J:224754
First Author: van der Meulen T
Year: 2015
Journal: Nat Med
Title: Urocortin3 mediates somatostatin-dependent negative feedback control of insulin secretion.
Volume: 21
Issue: 7
Pages: 769-76
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Publication
23024263 | J:192374
First Author: Araújo TG
Year: 2012
Journal: Endocrinology
Title: Hepatocyte growth factor plays a key role in insulin resistance-associated compensatory mechanisms.
Volume: 153
Issue: 12
Pages: 5760-9
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Publication
25773177 | J:220678
First Author: Gao Q
Year: 2015
Journal: Am J Pathol
Title: PPARα-Deficient ob/ob Obese Mice Become More Obese and Manifest Severe Hepatic Steatosis Due to Decreased Fatty Acid Oxidation.
Volume: 185
Issue: 5
Pages: 1396-408
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Publication
22936178 | J:208485
First Author: Xu J
Year: 2012
Journal: Diabetes
Title: Enhanced Nrf2 activity worsens insulin resistance, impairs lipid accumulation in adipose tissue, and increases hepatic steatosis in leptin-deficient mice.
Volume: 61
Issue: 12
Pages: 3208-18
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Publication
28105518 | J:240958
First Author: Blasco-Baque V
Year: 2017
Journal: Diabetologia
Title: Associations between hepatic miRNA expression, liver triacylglycerols and gut microbiota during metabolic adaptation to high-fat diet in mice.
Volume: 60
Issue: 4
Pages: 690-700
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Publication
32451485 | J:296951
First Author: Shen Q
Year: 2020
Journal: Nat Neurosci
Title: Reversal of prolonged obesity-associated cerebrovascular dysfunction by inhibiting microglial Tak1.
Volume: 23
Issue: 7
Pages: 832-841
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Publication
21356196 | J:171952
First Author: Tsurutani Y
Year: 2011
Journal: Biochem Biophys Res Commun
Title: The roles of transforming growth factor-β and Smad3 signaling in adipocyte differentiation and obesity.
Volume: 407
Issue: 1
Pages: 68-73
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Publication
26348837 | J:228916
First Author: Kluth O
Year: 2015
Journal: PLoS Genet
Title: Identification of Four Mouse Diabetes Candidate Genes Altering β-Cell Proliferation.
Volume: 11
Issue: 9
Pages: e1005506
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Publication
12431986 | J:81727
First Author: Yamauchi T
Year: 2003
Journal: J Biol Chem
Title: Globular adiponectin protected ob/ob mice from diabetes and ApoE-deficient mice from atherosclerosis.
Volume: 278
Issue: 4
Pages: 2461-8
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Publication
20603014 | J:167939
First Author: Cao L
Year: 2010
Journal: Cell
Title: Environmental and genetic activation of a brain-adipocyte BDNF/leptin axis causes cancer remission and inhibition.
Volume: 142
Issue: 1
Pages: 52-64
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Publication
23235530 | J:196510
First Author: Rodero MP
Year: 2013
Journal: J Invest Dermatol
Title: Reduced Il17a expression distinguishes a Ly6c(lo)MHCII(hi) macrophage population promoting wound healing.
Volume: 133
Issue: 3
Pages: 783-92
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Publication
11340336 | J:69137
First Author: Arvaniti K
Year: 2001
Journal: Neuroendocrinology
Title: Effects of leptin and corticosterone on the expression of corticotropin-releasing hormone, agouti-related protein, and proopiomelanocortin in the brain of ob/ob mouse.
Volume: 73
Issue: 4
Pages: 227-36
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Publication
22253718 | J:184323
First Author: Sáinz N
Year: 2012
Journal: PLoS One
Title: Leptin reduces the expression and increases the phosphorylation of the negative regulators of GLUT4 traffic TBC1D1 and TBC1D4 in muscle of ob/ob mice.
Volume: 7
Issue: 1
Pages: e29389
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Publication
20410123 | J:159836
First Author: Leshan RL
Year: 2010
Journal: J Neurosci
Title: Ventral tegmental area leptin receptor neurons specifically project to and regulate cocaine- and amphetamine-regulated transcript neurons of the extended central amygdala.
Volume: 30
Issue: 16
Pages: 5713-23
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Publication
24812663 | J:212751
First Author: Bellefontaine N
Year: 2014
Journal: J Clin Invest
Title: Leptin-dependent neuronal NO signaling in the preoptic hypothalamus facilitates reproduction.
Volume: 124
Issue: 6
Pages: 2550-9
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Publication
24270983 | J:229061
First Author: Albiero M
Year: 2014
Journal: Diabetes
Title: Diabetes causes bone marrow autonomic neuropathy and impairs stem cell mobilization via dysregulated p66Shc and Sirt1.
Volume: 63
Issue: 4
Pages: 1353-65
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Publication
9832419 | J:110666
First Author: Uysal KT
Year: 1998
Journal: Endocrinology
Title: Functional analysis of tumor necrosis factor (TNF) receptors in TNF-alpha-mediated insulin resistance in genetic obesity.
Volume: 139
Issue: 12
Pages: 4832-8
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Publication
26268630 | J:224994
 
First Author: Uno K
Year: 2015
Journal: Nat Commun
Title: A hepatic amino acid/mTOR/S6K-dependent signalling pathway modulates systemic lipid metabolism via neuronal signals.
Volume: 6
Pages: 7940
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Publication
22396530 | J:184470
First Author: Ji Y
Year: 2012
Journal: J Biol Chem
Title: Activation of natural killer T cells promotes M2 Macrophage polarization in adipose tissue and improves systemic glucose tolerance via interleukin-4 (IL-4)/STAT6 protein signaling axis in obesity.
Volume: 287
Issue: 17
Pages: 13561-71
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Publication
23803760 | J:204711
First Author: Yoshimoto S
Year: 2013
Journal: Nature
Title: Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome.
Volume: 499
Issue: 7456
Pages: 97-101
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Publication
27573812 | J:237232
First Author: Bi P
Year: 2016
Journal: J Exp Med
Title: Notch activation drives adipocyte dedifferentiation and tumorigenic transformation in mice.
Volume: 213
Issue: 10
Pages: 2019-37
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Publication
16981010 | J:115008
First Author: Valerio A
Year: 2006
Journal: J Clin Invest
Title: TNF-alpha downregulates eNOS expression and mitochondrial biogenesis in fat and muscle of obese rodents.
Volume: 116
Issue: 10
Pages: 2791-8
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Publication
22503562 | J:184607
First Author: Ozcan L
Year: 2012
Journal: Cell Metab
Title: Calcium signaling through CaMKII regulates hepatic glucose production in fasting and obesity.
Volume: 15
Issue: 5
Pages: 739-51
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Publication
15805118 | J:98746
First Author: Sugita H
Year: 2005
Journal: J Biol Chem
Title: Inducible nitric-oxide synthase and NO donor induce insulin receptor substrate-1 degradation in skeletal muscle cells.
Volume: 280
Issue: 14
Pages: 14203-11
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Publication
18977759 | J:143770
First Author: Ito A
Year: 2008
Journal: J Biol Chem
Title: Role of CC chemokine receptor 2 in bone marrow cells in the recruitment of macrophages into obese adipose tissue.
Volume: 283
Issue: 51
Pages: 35715-23
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Publication
24561619 | J:212985
First Author: Sakamaki J
Year: 2014
Journal: Nat Cell Biol
Title: Role of the SIK2-p35-PJA2 complex in pancreatic β-cell functional compensation.
Volume: 16
Issue: 3
Pages: 234-44
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Publication
28340340 | J:241361
First Author: Sharabi K
Year: 2017
Journal: Cell
Title: Selective Chemical Inhibition of PGC-1α Gluconeogenic Activity Ameliorates Type 2 Diabetes.
Volume: 169
Issue: 1
Pages: 148-160.e15
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Publication
19656487 | J:151971
First Author: Leinninger GM
Year: 2009
Journal: Cell Metab
Title: Leptin acts via leptin receptor-expressing lateral hypothalamic neurons to modulate the mesolimbic dopamine system and suppress feeding.
Volume: 10
Issue: 2
Pages: 89-98
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Publication
22261820 | J:316227
First Author: Zhang Y
Year: 2012
Journal: Mol Endocrinol
Title: Loss of FXR protects against diet-induced obesity and accelerates liver carcinogenesis in ob/ob mice.
Volume: 26
Issue: 2
Pages: 272-80
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Publication
18519977 | J:139764
First Author: Chen Z
Year: 2008
Journal: J Lipid Res
Title: ApoB100 is required for increased VLDL-triglyceride secretion by microsomal triglyceride transfer protein in ob/ob mice.
Volume: 49
Issue: 9
Pages: 2013-22
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Publication
19706524 | J:151994
First Author: Wu X
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Selective activation of FGFR4 by an FGF19 variant does not improve glucose metabolism in ob/ob mice.
Volume: 106
Issue: 34
Pages: 14379-84
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Publication
23071089 | J:192861
First Author: Takahashi A
Year: 2012
Journal: Mol Cell Biol
Title: Tob2 inhibits peroxisome proliferator-activated receptor γ2 expression by sequestering Smads and C/EBPα during adipocyte differentiation.
Volume: 32
Issue: 24
Pages: 5067-77
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Publication
21533112 | J:172393
First Author: Lloyd DJ
Year: 2011
Journal: PLoS One
Title: A volumetric method for quantifying atherosclerosis in mice by using microCT: comparison to en face.
Volume: 6
Issue: 4
Pages: e18800
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Publication
24241534 | J:208982
First Author: Sha H
Year: 2014
Journal: Diabetes
Title: Adipocyte spliced form of X-box-binding protein 1 promotes adiponectin multimerization and systemic glucose homeostasis.
Volume: 63
Issue: 3
Pages: 867-79
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Publication
28363698 | J:255912
First Author: Zhou Q
Year: 2017
Journal: Biochim Biophys Acta
Title: Dihydromyricetin prevents obesity-induced slow-twitch-fiber reduction partially via FLCN/FNIP1/AMPK pathway.
Volume: 1863
Issue: 6
Pages: 1282-1291
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Publication
31564684 | J:297975
First Author: Aibara D
Year: 2020
Journal: Endocr J
Title: Fat-specific protein 27b is regulated by hepatic peroxisome proliferator-activated receptor γ in hepatic steatosis.
Volume: 67
Issue: 1
Pages: 37-44
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Publication
22009939 | J:180625
First Author: Huang J
Year: 2012
Journal: FASEB J
Title: Sustained activation of PPARα by endogenous ligands increases hepatic fatty acid oxidation and prevents obesity in ob/ob mice.
Volume: 26
Issue: 2
Pages: 628-38
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Publication
25043058 | J:217106
First Author: Suh JM
Year: 2014
Journal: Nature
Title: Endocrinization of FGF1 produces a neomorphic and potent insulin sensitizer.
Volume: 513
Issue: 7518
Pages: 436-9
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Publication
12925742 | J:94820
First Author: Ishii M
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Targeted disruption of GPR7, the endogenous receptor for neuropeptides B and W, leads to metabolic defects and adult-onset obesity.
Volume: 100
Issue: 18
Pages: 10540-5
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Publication
27935966 | J:237488
First Author: Keller MP
Year: 2016
Journal: PLoS Genet
Title: The Transcription Factor Nfatc2 Regulates β-Cell Proliferation and Genes Associated with Type 2 Diabetes in Mouse and Human Islets.
Volume: 12
Issue: 12
Pages: e1006466
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9139806 | J:40012
First Author: Kesterson RA
Year: 1997
Journal: Mol Endocrinol
Title: Induction of neuropeptide Y gene expression in the dorsal medial hypothalamic nucleus in two models of the agouti obesity syndrome.
Volume: 11
Issue: 5
Pages: 630-7
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Publication
33567453 | J:302279
 
First Author: Bhattacharjee J
Year: 2021
Journal: Endocrinology
Title: Hepatic Ago2 Regulates PPARα for Oxidative Metabolism Linked to Glycemic Control in Obesity and Post Bariatric Surgery.
Volume: 162
Issue: 4
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Publication
24595352 | J:229497
First Author: Hall AM
Year: 2014
Journal: Diabetes
Title: Abrogating monoacylglycerol acyltransferase activity in liver improves glucose tolerance and hepatic insulin signaling in obese mice.
Volume: 63
Issue: 7
Pages: 2284-96
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Publication
16879220 | J:135847
First Author: Oishi K
Year: 2006
Journal: J Thromb Haemost
Title: CLOCK is involved in obesity-induced disordered fibrinolysis in ob/ob mice by regulating PAI-1 gene expression.
Volume: 4
Issue: 8
Pages: 1774-80
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Publication
11078460 | J:65482
First Author: Makimura H
Year: 2000
Journal: Diabetes
Title: Adrenalectomy reverses obese phenotype and restores hypothalamic melanocortin tone in leptin-deficient ob/ob mice.
Volume: 49
Issue: 11
Pages: 1917-23
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11078464 | J:65486
First Author: Stoehr JP
Year: 2000
Journal: Diabetes
Title: Genetic obesity unmasks nonlinear interactions between murine type 2 diabetes susceptibility loci.
Volume: 49
Issue: 11
Pages: 1946-54
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Publication
23542898 | J:213303
First Author: Graham MJ
Year: 2013
Journal: Circ Res
Title: Antisense oligonucleotide inhibition of apolipoprotein C-III reduces plasma triglycerides in rodents, nonhuman primates, and humans.
Volume: 112
Issue: 11
Pages: 1479-90
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25395359 | J:217398
First Author: Sajan MP
Year: 2015
Journal: J Lipid Res
Title: Hepatic insulin resistance in ob/ob mice involves increases in ceramide, aPKC activity, and selective impairment of Akt-dependent FoxO1 phosphorylation.
Volume: 56
Issue: 1
Pages: 70-80
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Publication
22700774 | J:189083
First Author: van der Velde M
Year: 2012
Journal: Endocrinology
Title: An age-dependent interaction with leptin unmasks ghrelin's bone-protective effects.
Volume: 153
Issue: 8
Pages: 3593-602
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Publication
18334608 | J:135996
First Author: Allen DL
Year: 2008
Journal: Am J Physiol Endocrinol Metab
Title: Myostatin, activin receptor IIb, and follistatin-like-3 gene expression are altered in adipose tissue and skeletal muscle of obese mice.
Volume: 294
Issue: 5
Pages: E918-27
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Publication
24074871 | J:205218
First Author: Oury F
Year: 2013
Journal: Cell
Title: Maternal and offspring pools of osteocalcin influence brain development and functions.
Volume: 155
Issue: 1
Pages: 228-41
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Publication
27941791 | J:251393
First Author: Hahm E
Year: 2017
Journal: Nat Med
Title: Bone marrow-derived immature myeloid cells are a main source of circulating suPAR contributing to proteinuric kidney disease.
Volume: 23
Issue: 1
Pages: 100-106
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Publication
25068621 | J:225625
 
First Author: Guo W
Year: 2014
Journal: J Mol Cell Cardiol
Title: QKI deficiency promotes FoxO1 mediated nitrosative stress and endoplasmic reticulum stress contributing to increased vulnerability to ischemic injury in diabetic heart.
Volume: 75
Pages: 131-40
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