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Search results 1901 to 2000 out of 2672 for Mapt

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Type Details Score
Publication
37014857 | J:336396
First Author: Dong Q
Year: 2023
Journal: Proc Natl Acad Sci U S A
Title: Mutant β(1)-adrenergic receptor improves REM sleep and ameliorates tau accumulation in a mouse model of tauopathy.
Volume: 120
Issue: 15
Pages: e2221686120
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Publication
30232451 | J:267185
First Author: Bussian TJ
Year: 2018
Journal: Nature
Title: Clearance of senescent glial cells prevents tau-dependent pathology and cognitive decline.
Volume: 562
Issue: 7728
Pages: 578-582
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Publication
37957317 | J:343279
First Author: Nelson MR
Year: 2023
Journal: Nat Neurosci
Title: The APOE-R136S mutation protects against APOE4-driven Tau pathology, neurodegeneration and neuroinflammation.
Volume: 26
Issue: 12
Pages: 2104-2121
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Publication
38941274 | J:351620
First Author: Zubia MV
Year: 2024
Journal: Proc Natl Acad Sci U S A
Title: TMEM16F exacerbates tau pathology and mediates phosphatidylserine exposure in phospho-tau-burdened neurons.
Volume: 121
Issue: 27
Pages: e2311831121
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Publication
33831349 | J:311275
First Author: Wang C
Year: 2021
Journal: Neuron
Title: Selective removal of astrocytic APOE4 strongly protects against tau-mediated neurodegeneration and decreases synaptic phagocytosis by microglia.
Volume: 109
Issue: 10
Pages: 1657-1674.e7
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Strain
MGI:7544905 | B6(SJL)-Apoe<tm1.1(APOE*4)Adiuj> Tc(HSA17)2Mdk App<em1Adiuj>/J
Attribute String: endonuclease-mediated mutation, mutant strain, targeted mutation
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Strain
MGI:6369611 | B6(SJL)-Apoe<tm1.1(APOE*4)Adiuj> Tc(HSA17)1Mdk App<em1Adiuj>/AdiujJ
Attribute String: endonuclease-mediated mutation, targeted mutation, mutant strain
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Strain
MGI:7764466 | B6(Cg)-Apoe<tm1.1(APOE*4)Adiuj> Tc(HSA17)1Mdk App<em2Aduci>/AduciJ
Attribute String: mutant strain, endonuclease-mediated mutation, other, targeted mutation
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Strain
MGI:7764465 | B6(Cg)-Apoe<tm1.1(APOE*4)Adiuj> Tc(HSA17)1Mdk App<tm1.1Aduci>/AduciJ
Attribute String: targeted mutation, other, mutant strain
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Strain
MGI:7576972 | B6J.B6N(CBA)-Tc(HSA17)1Mdk Psen1<tm1.1(PSEN1)Mdk> App<tm1.1(APP)Mdk>/J
Attribute String: congenic, mutant strain, targeted mutation
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Genotype
Genotype
Symbol: Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/? Tg(Thy1-MAPT*)30Schd/?
Background: involves: C57BL/6 * C57BL/6J * CBA * SJL
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Camk2a-tTA)1Mmay/? Zbtb20/? Tg(tetO-MAPT*A152T)L1Lms/?
Background: involves: C57BL/6 * C57BL/6J * DBA/2
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Camk2a-tTA)1Mmay/? Zbtb20/? Tg(tetO-MAPT)32Lms/?
Background: involves: C57BL/6 * C57BL/6J * DBA/2
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Camk2a-tTA)1Mmay/? Tg(PDGFB-APPSwInd)J9Lms/? Tg(tetO-MAPT*A152T)L1Lms/?
Background: involves: C57BL/6 * C57BL/6J * DBA/2
Zygosity: cx
Has Mutant Allele: true
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Publication
25680266 | J:221905
First Author: Jensen MM
Year: 2015
Journal: Neurobiol Aging
Title: Prostate stem cell antigen interacts with nicotinic acetylcholine receptors and is affected in Alzheimer's disease.
Volume: 36
Issue: 4
Pages: 1629-1638
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Publication
39532095 | J:360629
First Author: Guo JL
Year: 2025
Journal: Cell
Title: Decreased lipidated ApoE-receptor interactions confer protection against pathogenicity of ApoE and its lipid cargoes in lysosomes.
Volume: 188
Issue: 1
Pages: 187-206.e26
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Publication
37995685 | J:346146
First Author: Litvinchuk A
Year: 2024
Journal: Neuron
Title: Amelioration of Tau and ApoE4-linked glial lipid accumulation and neurodegeneration with an LXR agonist.
Volume: 112
Issue: 3
Pages: 384-403.e8
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Publication
36890231 | J:355378
First Author: Chen X
Year: 2023
Journal: Nature
Title: Microglia-mediated T cell infiltration drives neurodegeneration in tauopathy.
Volume: 615
Issue: 7953
Pages: 668-677
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Publication
26494278 | J:255120
First Author: Bien-Ly N
Year: 2015
Journal: Neuron
Title: Lack of Widespread BBB Disruption in Alzheimer's Disease Models: Focus on Therapeutic Antibodies.
Volume: 88
Issue: 2
Pages: 289-97
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Publication
30185465 | J:266518
First Author: Gwon Y
Year: 2018
Journal: J Neurosci
Title: TOM1 Regulates Neuronal Accumulation of Amyloid-β Oligomers by FcγRIIb2 Variant in Alzheimer's Disease.
Volume: 38
Issue: 42
Pages: 9001-9018
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Publication
24828645 | J:211264
First Author: Shilling D
Year: 2014
Journal: J Neurosci
Title: Suppression of InsP3 receptor-mediated Ca2+ signaling alleviates mutant presenilin-linked familial Alzheimer's disease pathogenesis.
Volume: 34
Issue: 20
Pages: 6910-23
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Publication
21741124 | J:188201
First Author: Minami SS
Year: 2012
Journal: Neurobiol Aging
Title: Fyn knock-down increases Aβ, decreases phospho-tau, and worsens spatial learning in 3×Tg-AD mice.
Volume: 33
Issue: 4
Pages: 825.e15-24
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Publication
27499089 | J:283300
First Author: Di Meco A
Year: 2017
Journal: Biol Psychiatry
Title: 12/15-Lipoxygenase Inhibition Reverses Cognitive Impairment, Brain Amyloidosis, and Tau Pathology by Stimulating Autophagy in Aged Triple Transgenic Mice.
Volume: 81
Issue: 2
Pages: 92-100
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Strain
MGI:4440866 | B6;129-Soat1<tm1Far> Psen1<tm1Mpm> Tg(APPSwe,tauP301L)1Lfa/J
Attribute String: transgenic, targeted mutation, mutant stock
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Publication
37105172 | J:341030
First Author: Festa BP
Year: 2023
Journal: Neuron
Title: Microglial-to-neuronal CCR5 signaling regulates autophagy in neurodegeneration.
Volume: 111
Issue: 13
Pages: 2021-2037.e12
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Publication
27273428 | J:319915
First Author: Uribe-Arias A
Year: 2016
Journal: J Neurochem
Title: p120-catenin is necessary for neuroprotection induced by CDK5 silencing in models of Alzheimer's disease.
Volume: 138
Issue: 4
Pages: 624-39
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Publication
24332986 | J:212730
First Author: Joshi YB
Year: 2014
Journal: Neurobiol Aging
Title: Modulation of lipopolysaccharide-induced memory insult, γ-secretase, and neuroinflammation in triple transgenic mice by 5-lipoxygenase.
Volume: 35
Issue: 5
Pages: 1024-31
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Publication
23634895 | J:214888
First Author: Joshi YB
Year: 2013
Journal: Aging Cell
Title: Knockout of 5-lipoxygenase prevents dexamethasone-induced tau pathology in 3xTg mice.
Volume: 12
Issue: 4
Pages: 706-11
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Publication
25122659 | J:216418
First Author: Joshi YB
Year: 2014
Journal: Hum Mol Genet
Title: Absence of ALOX5 gene prevents stress-induced memory deficits, synaptic dysfunction and tauopathy in a mouse model of Alzheimer's disease.
Volume: 23
Issue: 25
Pages: 6894-902
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Publication
31814000 | J:285091
First Author: Kim J
Year: 2020
Journal: Hum Mol Genet
Title: Ca2+-permeable TRPV1 pain receptor knockout rescues memory deficits and reduces amyloid-β and tau in a mouse model of Alzheimer's disease.
Volume: 29
Issue: 2
Pages: 228-237
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Strain
MGI:6159260 | B6.Cg-Tg(APPSwe,tauP301L)1Lfa Psen1<tm1Mpm>/J
Attribute String: congenic, mutant strain, targeted mutation, transgenic
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Strain
MGI:5003441 | B6.Cg-Psen1<tm1Mpm> Tg(APPSwe,tauP301L)1Lfa
Attribute String: congenic, mutant strain, targeted mutation, transgenic
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Strain
MGI:6392809 | 129S4.Cg-Tg(APPSwe,tauP301L)1Lfa Psen1<tm1Mpm>/LfaJ
Attribute String: mutant strain, congenic, targeted mutation, transgenic
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Strain
MGI:2673730 | B6;129-Tg(APPSwe,tauP301L)1Lfa Psen1<tm1Mpm>/Mmjax
Attribute String: targeted mutation, transgenic, mutant stock
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Strain
MGI:6503832 | B6.Cg-Tg(APPSwe,tauP301L)1Lfa Psen1<tm1Mpm>/2J
Attribute String: congenic, mutant strain, targeted mutation, transgenic
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Publication
24103194 | J:206614
 
First Author: Hawkes CA
Year: 2013
Journal: Exp Neurol
Title: Stroke-induced opposite and age-dependent changes of vessel-associated markers in co-morbid transgenic mice with Alzheimer-like alterations.
Volume: 250
Pages: 270-81
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Publication
37619698 | J:339650
 
First Author: Philipsberg PA
Year: 2023
Journal: Neurosci Lett
Title: Chronotate: An open-source tool for manual timestamping and quantification of animal behavior.
Volume: 814
Pages: 137461
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Publication
38187357 | J:344310
 
First Author: Wang H
Year: 2023
Journal: Front Aging Neurosci
Title: PKCε activator protects hippocampal microvascular disruption and memory defect in 3×Tg-Alzheimer's disease mice with cerebral microinfarcts.
Volume: 15
Pages: 1272361
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Publication
35153718 | J:321582
 
First Author: Tureckova J
Year: 2021
Journal: Front Aging Neurosci
Title: Compromised Astrocyte Swelling/Volume Regulation in the Hippocampus of the Triple Transgenic Mouse Model of Alzheimer's Disease.
Volume: 13
Pages: 783120
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Publication
27875002 | J:350165
First Author: Tafoya MA
Year: 2017
Journal: J Magn Reson Imaging
Title: Superparamagnetic nanoparticle-enhanced MRI of Alzheimer's disease plaques and activated microglia in 3X transgenic mouse brains: Contrast optimization.
Volume: 46
Issue: 2
Pages: 574-588
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Publication
18687504 | J:161837
First Author: Jo DG
Year: 2010
Journal: Neurobiol Aging
Title: Evidence that gamma-secretase mediates oxidative stress-induced beta-secretase expression in Alzheimer's disease.
Volume: 31
Issue: 6
Pages: 917-25
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Publication
23486975 | J:196598
First Author: Ghosh S
Year: 2013
Journal: J Neurosci
Title: Sustained interleukin-1β overexpression exacerbates tau pathology despite reduced amyloid burden in an Alzheimer's mouse model.
Volume: 33
Issue: 11
Pages: 5053-64
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Publication
39040060 | J:352150
First Author: Qiao Y
Year: 2024
Journal: iScience
Title: The role of m6A modification in the risk prediction and Notch1 pathway of Alzheimer's disease.
Volume: 27
Issue: 7
Pages: 110235
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Publication
35286012 | J:350790
First Author: Huang CY
Year: 2022
Journal: Environ Toxicol
Title: Edible folic acid and medicinal folinic acid produce cardioprotective effects in late-stage triple-transgenic Alzheimer's disease model mice by suppressing cardiac hypertrophy and fibrosis.
Volume: 37
Issue: 7
Pages: 1740-1749
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Publication
24316432 | J:210695
 
First Author: Song JM
Year: 2014
Journal: Exp Neurol
Title: A tetra(ethylene glycol) derivative of benzothiazole aniline ameliorates dendritic spine density and cognitive function in a mouse model of Alzheimer's disease.
Volume: 252
Pages: 105-13
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Publication
28941799 | J:254181
First Author: Zandl-Lang M
Year: 2018
Journal: Biochim Biophys Acta
Title: Regulatory effects of simvastatin and apoJ on APP processing and amyloid-β clearance in blood-brain barrier endothelial cells.
Volume: 1863
Issue: 1
Pages: 40-60
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Publication
24268883 | J:212737
First Author: Rice RA
Year: 2014
Journal: Neurobiol Aging
Title: Age-related downregulation of the CaV3.1 T-type calcium channel as a mediator of amyloid beta production.
Volume: 35
Issue: 5
Pages: 1002-11
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Publication
24268884 | J:212736
First Author: Shin MK
Year: 2014
Journal: Neurobiol Aging
Title: Neuropep-1 ameliorates learning and memory deficits in an Alzheimer's disease mouse model, increases brain-derived neurotrophic factor expression in the brain, and causes reduction of amyloid beta plaques.
Volume: 35
Issue: 5
Pages: 990-1001
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Publication
17472708 | J:124130
First Author: Oddo S
Year: 2007
Journal: J Neurochem
Title: Genetically augmenting tau levels does not modulate the onset or progression of Abeta pathology in transgenic mice.
Volume: 102
Issue: 4
Pages: 1053-63
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Publication
20332427 | J:185414
First Author: Cheung KH
Year: 2010
Journal: Sci Signal
Title: Gain-of-function enhancement of IP3 receptor modal gating by familial Alzheimer's disease-linked presenilin mutants in human cells and mouse neurons.
Volume: 3
Issue: 114
Pages: ra22
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Publication
39227892 | J:359285
First Author: Colussi C
Year: 2024
Journal: Stem Cell Res Ther
Title: Nucleoporin 153 deficiency in adult neural stem cells defines a pathological protein-network signature and defective neurogenesis in a mouse model of AD.
Volume: 15
Issue: 1
Pages: 275
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Publication
29760653 | J:324368
 
First Author: Zhang Q
Year: 2018
Journal: Front Mol Neurosci
Title: CK2 Phosphorylating I2PP2A/SET Mediates Tau Pathology and Cognitive Impairment.
Volume: 11
Pages: 146
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Publication
25446741 | J:223868
 
First Author: Cañete T
Year: 2015
Journal: Behav Brain Res
Title: Cognitive and emotional alterations in young Alzheimer's disease (3xTgAD) mice: effects of neonatal handling stimulation and sexual dimorphism.
Volume: 281
Pages: 156-71
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Publication
25446812 | J:223867
 
First Author: Stevens LM
Year: 2015
Journal: Behav Brain Res
Title: Reference and working memory deficits in the 3xTg-AD mouse between 2 and 15-months of age: a cross-sectional study.
Volume: 278
Pages: 496-505
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Publication
30872324 | J:276278
First Author: Aloni E
Year: 2019
Journal: J Neurosci
Title: Synaptopodin Deficiency Ameliorates Symptoms in the 3xTg Mouse Model of Alzheimer's Disease.
Volume: 39
Issue: 20
Pages: 3983-3992
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Publication
36009514 | J:350180
 
First Author: Jullienne A
Year: 2022
Journal: Biomedicines
Title: Progressive Vascular Abnormalities in the Aging 3xTg-AD Mouse Model of Alzheimer's Disease.
Volume: 10
Issue: 8
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Publication
23827221 | J:201677
 
First Author: Rodríguez JJ
Year: 2013
Journal: Neurosci Lett
Title: Increased densities of resting and activated microglia in the dentate gyrus follow senile plaque formation in the CA1 subfield of the hippocampus in the triple transgenic model of Alzheimer's disease.
Volume: 552
Pages: 129-34
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Publication
31055081 | J:283443
First Author: Fanaee-Danesh E
Year: 2019
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Astaxanthin exerts protective effects similar to bexarotene in Alzheimer's disease by modulating amyloid-beta and cholesterol homeostasis in blood-brain barrier endothelial cells.
Volume: 1865
Issue: 9
Pages: 2224-2245
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Publication
20042680 | J:156761
First Author: Martinez-Coria H
Year: 2010
Journal: Am J Pathol
Title: Memantine improves cognition and reduces Alzheimer's-like neuropathology in transgenic mice.
Volume: 176
Issue: 2
Pages: 870-80
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Publication
34896306 | J:319782
 
First Author: Nazari HK
Year: 2022
Journal: Exp Eye Res
Title: Age dependence of retinal vascular plexus attenuation in the triple transgenic mouse model of Alzheimer's disease.
Volume: 214
Pages: 108879
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Publication
36194703 | J:350182
First Author: Walter KR
Year: 2023
Journal: Am J Drug Alcohol Abuse
Title: Prenatal alcohol exposure causes persistent microglial activation and age- and sex- specific effects on cognition and metabolic outcomes in an Alzheimer's Disease mouse model.
Volume: 49
Issue: 3
Pages: 302-320
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Publication
28511979 | J:249623
 
First Author: Davis KE
Year: 2017
Journal: Behav Brain Res
Title: Water and T-maze protocols are equally efficient methods to assess spatial memory in 3xTg Alzheimer's disease mice.
Volume: 331
Pages: 54-66
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Publication
23618870 | J:211732
First Author: Edrey YH
Year: 2013
Journal: Neurobiol Aging
Title: Amyloid beta and the longest-lived rodent: the naked mole-rat as a model for natural protection from Alzheimer's disease.
Volume: 34
Issue: 10
Pages: 2352-60
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Publication
35095474 | J:319709
 
First Author: Liu J
Year: 2021
Journal: Front Aging Neurosci
Title: Preservation of Retinal Function Through Synaptic Stabilization in Alzheimer's Disease Model Mouse Retina by Lycium Barbarum Extracts.
Volume: 13
Pages: 788798
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Publication
23155407 | J:195586
First Author: Yan XX
Year: 2012
Journal: PLoS One
Title: Chronic temporal lobe epilepsy is associated with enhanced Alzheimer-like neuropathology in 3×Tg-AD mice.
Volume: 7
Issue: 11
Pages: e48782
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Publication
26778963 | J:310589
 
First Author: Piedrahita D
Year: 2015
Journal: Front Cell Neurosci
Title: β-Secretase 1's Targeting Reduces Hyperphosphorilated Tau, Implying Autophagy Actors in 3xTg-AD Mice.
Volume: 9
Pages: 498
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Publication
28641077 | J:244252
First Author: Qin X
Year: 2017
Journal: Am J Pathol
Title: Inhibition of Early Growth Response 1 in the Hippocampus Alleviates Neuropathology and Improves Cognition in an Alzheimer Model with Plaques and Tangles.
Volume: 187
Issue: 8
Pages: 1828-1847
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Publication
21531375 | J:173178
First Author: Sy M
Year: 2011
Journal: Am J Pathol
Title: Inflammation induced by infection potentiates tau pathological features in transgenic mice.
Volume: 178
Issue: 6
Pages: 2811-22
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Publication
23630570 | J:200630
First Author: Wu W
Year: 2013
Journal: PLoS One
Title: Expression of tryptophan 2,3-dioxygenase and production of kynurenine pathway metabolites in triple transgenic mice and human Alzheimer's disease brain.
Volume: 8
Issue: 4
Pages: e59749
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Publication
33155636 | J:300029
First Author: Kam MK
Year: 2020
Journal: Biochem J
Title: Amyloid-beta oligomers induce Parkin-mediated mitophagy by reducing Miro1.
Volume: 477
Issue: 23
Pages: 4581-4597
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Publication
23804095 | J:199637
First Author: Arsenault D
Year: 2013
Journal: J Neurosci
Title: PAK inactivation impairs social recognition in 3xTg-AD Mice without increasing brain deposition of tau and Aβ.
Volume: 33
Issue: 26
Pages: 10729-40
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Publication
24887583 | J:214748
 
First Author: Walls KC
Year: 2014
Journal: Neurosci Lett
Title: p-Tau immunotherapy reduces soluble and insoluble tau in aged 3xTg-AD mice.
Volume: 575
Pages: 96-100
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Publication
39547338 | J:360793
 
First Author: Wang ZJ
Year: 2024
Journal: Neuroscience
Title: Semaglutide promotes the transition of microglia from M1 to M2 type to reduce brain inflammation in APP/PS1/tau mice.
Volume: 563
Pages: 222-234
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Publication
39424953 | J:359336
First Author: Xiong W
Year: 2024
Journal: EMBO J
Title: The mitochondrial long non-coding RNA lncMtloop regulates mitochondrial transcription and suppresses Alzheimer's disease.
Volume: 43
Issue: 23
Pages: 6001-6031
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Publication
15748844 | J:99604
First Author: Billings LM
Year: 2005
Journal: Neuron
Title: Intraneuronal Abeta causes the onset of early Alzheimer's disease-related cognitive deficits in transgenic mice.
Volume: 45
Issue: 5
Pages: 675-88
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Publication
22587890 | J:186440
 
First Author: Rosario ER
Year: 2012
Journal: Brain Res
Title: Evaluation of the effects of testosterone and luteinizing hormone on regulation of β-amyloid in male 3xTg-AD mice.
Volume: 1466
Pages: 137-45
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Publication
28688899 | J:249714
 
First Author: Velazquez R
Year: 2017
Journal: Neurobiol Aging
Title: Central insulin dysregulation and energy dyshomeostasis in two mouse models of Alzheimer's disease.
Volume: 58
Pages: 1-13
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Publication
27777112 | J:350191
 
First Author: Schaeffer EL
Year: 2017
Journal: Ann Anat
Title: Stereological investigation of the CA1 pyramidal cell layer in untreated and lithium-treated 3xTg-AD and wild-type mice.
Volume: 209
Pages: 51-60
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Publication
27460145 | J:239134
 
First Author: Thomsen MS
Year: 2016
Journal: Neurobiol Aging
Title: Lynx1 and Aβ1-42 bind competitively to multiple nicotinic acetylcholine receptor subtypes.
Volume: 46
Pages: 13-21
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Publication
37735133 | J:350206
First Author: Jin Y
Year: 2023
Journal: J Integr Neurosci
Title: Effect of Physical Exercise on Mitochondrial Dysfunction and Purkinje Cell Survival in the Cerebellum of 3xTg-AD Mice.
Volume: 22
Issue: 5
Pages: 117
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Publication
23523959 | J:197629
 
First Author: Torres-Lista V
Year: 2013
Journal: Behav Brain Res
Title: Impairment of nesting behaviour in 3xTg-AD mice.
Volume: 247
Pages: 153-7
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Publication
37789692 | J:350208
First Author: Li J
Year: 2024
Journal: CNS Neurosci Ther
Title: Co-housing with Alzheimer's disease mice induces changes in gut microbiota and impairment of learning and memory in control mice.
Volume: 30
Issue: 4
Pages: e14491
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Publication
17456772 | J:121081
First Author: Caccamo A
Year: 2007
Journal: Am J Pathol
Title: Lithium reduces tau phosphorylation but not A beta or working memory deficits in a transgenic model with both plaques and tangles.
Volume: 170
Issue: 5
Pages: 1669-75
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Publication
38510467 | J:348968
 
First Author: Medeiros D
Year: 2024
Journal: Front Neurosci
Title: Slowing Alzheimer's disease progression through probiotic supplementation.
Volume: 18
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