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Search results 1901 to 2000 out of 3345 for Myb

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Type Details Score
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Down CF
Year: 2012
Journal: Biochim Biophys Acta
Title: Binding of FoxM1 to G2/M gene promoters is dependent upon B-Myb.
Volume: 1819
Issue: 8
Pages: 855-62
Publication
First Author: Rambaud J
Year: 2009
Journal: J Biol Chem
Title: TIF1beta/KAP-1 is a coactivator of the orphan nuclear receptor NGFI-B/Nur77.
Volume: 284
Issue: 21
Pages: 14147-56
Publication  
First Author: Hollander WF
Year: 1973
Journal: Mouse News Lett
Title: sr and Tw are not alleles, and seem independent
Volume: 48
Pages: 33
Strain
Attribute String: congenic, mutant strain, targeted mutation, spontaneous mutation
Publication
First Author: Dúcka M
Year: 2021
Journal: Neoplasia
Title: c-Myb interferes with inflammatory IL1α-NF-κB pathway in breast cancer cells.
Volume: 23
Issue: 3
Pages: 326-336
Allele
Name: intergenic site 3; targeted mutation 2.1, Liqun Luo
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
Allele
Name: intergenic site 3; targeted mutation 1.1, Liqun Luo
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
Genotype
Symbol: Zeb1/Zeb1
Background: B6.Cg-Zeb1/Zeb1
Zygosity: ht
Has Mutant Allele: true
Protein Domain
Type: Domain
Description: This entry represents the C-terminal domain of the RTC4 (restriction of telomere capping protein 4) protein from yeasts. In Saccharomyces cerevisiae, deletion of RTC4 affects the cell response to telomere uncapping []. This domain is also found in proteins that contain a DNA-binding myb domain.
Protein Domain
Type: Family
Description: This entry represents LIN-9-related proteins from plants (also known as proteins ALWAYS EARLY). In Arabidopsis thaliana, there are three ALWAYS EARLY homologues (AtALY1, AtALY2 and AtALY3). Unlike animal ALY/LIN-9 proteins, AtALY1 contains an additional N-terminal myb domain and a TUDOR related domain in part of the ALY/LIN-9 conserved domain [].
Protein Domain
Type: Domain
Description: This domain, found in L10-interacting MYB domain-containing protein (LIMYB) and At2g29880 from Arabidopsis, is related to Myb/SANT-like DNA binding domains. LIMYB is a transcription factor that associates with ribosomal protein promoters. It is involved in global translation suppression as an antiviral immunity strategy in plants [].
Protein Domain
Type: Family
Description: TMX2 contain the TRX domain, an N-terminal signal peptide, a potential transmembrane domain, an Myb DNA-binding domain repeat signature, an endoplasmic reticulum (ER) membrane retention signal (KKXX-like motif), and a dileucine motif in the tail. In TMX2, the TRX domain redox active CXXC motif is replaced with SXXC [, ]. Its function is not clear. Homologues are found only in metazoa.
Publication
First Author: Yamauchi T
Year: 2008
Journal: EMBO J
Title: A B-Myb complex containing clathrin and filamin is required for mitotic spindle function.
Volume: 27
Issue: 13
Pages: 1852-62
Publication  
First Author: Rai R
Year: 2016
Journal: Nat Commun
Title: TRF2-RAP1 is required to protect telomeres from engaging in homologous recombination-mediated deletions and fusions.
Volume: 7
Pages: 10881
Publication
First Author: Weng H
Year: 2018
Journal: Cell Stem Cell
Title: METTL14 Inhibits Hematopoietic Stem/Progenitor Differentiation and Promotes Leukemogenesis via mRNA m6A Modification.
Volume: 22
Issue: 2
Pages: 191-205.e9
Publication
First Author: Capellera-Garcia S
Year: 2016
Journal: Cell Rep
Title: Defining the Minimal Factors Required for Erythropoiesis through Direct Lineage Conversion.
Volume: 15
Issue: 11
Pages: 2550-62
Publication
First Author: Yu T
Year: 2022
Journal: RNA
Title: A-MYB/TCFL5 regulatory architecture ensures the production of pachytene piRNAs in placental mammals.
Volume: 29
Issue: 1
Pages: 30-43
Publication
First Author: Eldeeb M
Year: 2023
Journal: Cell Rep
Title: A fetal tumor suppressor axis abrogates MLL-fusion-driven acute myeloid leukemia.
Volume: 42
Issue: 2
Pages: 112099
Publication
First Author: Yamagoe S
Year: 1998
Journal: Biochim Biophys Acta
Title: Molecular cloning of human and bovine LECT2 having a neutrophil chemotactic activity and its specific expression in the liver.
Volume: 1396
Issue: 1
Pages: 105-13
Publication
First Author: Kitajima T
Year: 1992
Journal: Clin Immunol Immunopathol
Title: Histological detection of c-myb and c-myc proto-oncogene expression in infiltrating cells in cutaneous lupus erythematosus-like lesions of MRL/l mice by in situ hybridization.
Volume: 62
Issue: 1 Pt 1
Pages: 119-23
Publication  
First Author: Bies J
Year: 1997
Journal: Leukemia
Title: MuLV-insertional mutagenesis of c-myb and Mml1 in a murine model for promonocytic leukemia.
Volume: 11 Suppl 3
Pages: 247-50
Publication
First Author: Bhagwat AS
Year: 2016
Journal: Cell Rep
Title: BET Bromodomain Inhibition Releases the Mediator Complex from Select cis-Regulatory Elements.
Volume: 15
Issue: 3
Pages: 519-530
Publication
First Author: Hyrenius-Wittsten A
Year: 2018
Journal: Nat Commun
Title: De novo activating mutations drive clonal evolution and enhance clonal fitness in KMT2A-rearranged leukemia.
Volume: 9
Issue: 1
Pages: 1770
Publication
First Author: Wang J
Year: 2020
Journal: Cell Stem Cell
Title: Leukemogenic Chromatin Alterations Promote AML Leukemia Stem Cells via a KDM4C-ALKBH5-AXL Signaling Axis.
Volume: 27
Issue: 1
Pages: 81-97.e8
Publication
First Author: Kim J
Year: 2024
Journal: Cell Rep
Title: An enhancer RNA recruits KMT2A to regulate transcription of Myb.
Volume: 43
Issue: 7
Pages: 114378
Publication
First Author: Phelps-Durr TL
Year: 2005
Journal: Plant Cell
Title: Maize rough sheath2 and its Arabidopsis orthologue ASYMMETRIC LEAVES1 interact with HIRA, a predicted histone chaperone, to maintain knox gene silencing and determinacy during organogenesis.
Volume: 17
Issue: 11
Pages: 2886-98
Publication
First Author: Ellgaard L
Year: 2005
Journal: EMBO Rep
Title: The human protein disulphide isomerase family: substrate interactions and functional properties.
Volume: 6
Issue: 1
Pages: 28-32
Publication
First Author: Meng X
Year: 2003
Journal: Biochem Genet
Title: Cloning and identification of a novel cDNA coding thioredoxin-related transmembrane protein 2.
Volume: 41
Issue: 3-4
Pages: 99-106
Publication
First Author: Theodoris G
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Conservation and molecular dissection of ROUGH SHEATH2 and ASYMMETRIC LEAVES1 function in leaf development.
Volume: 100
Issue: 11
Pages: 6837-42
Publication
First Author: Morimoto R
Year: 2009
Journal: Plant Mol Biol
Title: Functional conservation of wheat orthologs of maize rough sheath1 and rough sheath2 genes.
Volume: 69
Issue: 3
Pages: 273-85
Publication
First Author: Grillari J
Year: 2009
Journal: J Biol Chem
Title: Blom7alpha is a novel heterogeneous nuclear ribonucleoprotein K homology domain protein involved in pre-mRNA splicing that interacts with SNEVPrp19-Pso4.
Volume: 284
Issue: 42
Pages: 29193-204
Publication
First Author: Löscher M
Year: 2012
Journal: PLoS One
Title: Inhibition of pre-mRNA splicing by a synthetic Blom7α-interacting small RNA.
Volume: 7
Issue: 10
Pages: e47497
Publication
First Author: Mohan KN
Year: 2011
Journal: Mol Cell Biol
Title: Distinct roles of DMAP1 in mouse development.
Volume: 31
Issue: 9
Pages: 1861-9
Publication
First Author: Dai S
Year: 2011
Journal: Plant Cell
Title: BROTHER OF LUX ARRHYTHMO is a component of the Arabidopsis circadian clock.
Volume: 23
Issue: 3
Pages: 961-72
Publication
First Author: Nusinow DA
Year: 2011
Journal: Nature
Title: The ELF4-ELF3-LUX complex links the circadian clock to diurnal control of hypocotyl growth.
Volume: 475
Issue: 7356
Pages: 398-402
Publication
First Author: Zhai H
Year: 2010
Journal: Biochem Biophys Res Commun
Title: A single-repeat R3-MYB transcription factor MYBC1 negatively regulates freezing tolerance in Arabidopsis.
Volume: 394
Issue: 4
Pages: 1018-23
Protein Domain
Type: Domain
Description: This domain, approximately 90 residues, is mainly found in DNA methyltransferase 1-associated protein 1 (DAMP1), which plays an important role in development and maintenance of genome integrity in various mammalian species [, ]. It mainly consists of tandem repeats of three α-helices that are arranged in a helix-turn-helix motif and shows a structural similarity with SANT domain and Myb DNA-binding domain, indicating it contains a putative DNA-binding site [].
Protein Domain
Type: Family
Description: This entry represents a group of plant Myb domain proteins, including LUX, BOA and MYBC1 from Arabidopsis. LUX and BOA are transcription factors and critical components of the regulatory circuit of the circadian clock [, ]. LUX also binds toELF3 and associates with ELF4 in a diurnal complex which is required for the expression of the growth-promoting transcription factors PIF4 and PIF5 and subsequent hypocotyl growth in the early evening []. MYBC1 has been shown to negatively regulate freezing tolerance in Arabidopsis [].
Protein Domain
Type: Domain
Description: This domain adopts a secondary structure consisting of a pair of long, antiparallel α-helices (thestem) that support a three-helix bundle (3HB) at their end. The 3HB contains a helix-turn-helix motif and is similar to the DNA binding domains of the bacterial site-specific recombinases, and of eukaryotic Myb and homeodomain transcription factors. The Tower domain has an important role in the tumour suppressor function of BRCA2, and is essential for appropriate binding of BRCA2 to DNA [].
Protein Domain
Type: Domain
Description: This entry represents the thioredoxin (TRX) domain found in thioredoxin-related transmembrane protein 2 (TMX2). In TMX2, the TRX domain redox active CXXC motif is replaced with SXXC. In addition to the TRX domain, TMX2 may contain an N-terminal signal peptide, a potential transmembrane domain, an Myb DNA-binding domain repeat signature, an endoplasmic reticulum (ER) membrane retention signal (KKXX-like motif), and a dileucine motif in the tail [, ].
Protein Domain
Type: Family
Description: This entry represents a group of Myb transcription factors from plants, including protein rough sheath 2 (RS2) and ASSYMMETRIC LEAVES1 (Asn1) [, ]. They repress Knotted1-type homeobox (KNOX) genes and are required to establish determinacy during leaf development. RS2/AS1 interacts with the DNA binding factor ASYMMETRIC LEAVES2, a predicted RNA binding protein (RIK, for RS2-Interacting KH protein), and a homologue of the chromatin-remodeling protein HIRA. Together with HIRA, RS2/AS1 mediates the epigenetic silencing of knox genes, possibly by modulating chromatin structure [].
Protein Domain
Type: Family
Description: This entry represents a group of KH domain containing proteins from eukaryotes, including RIK (rough sheath 2-interacting KH domain) from plants and BLOM7 (also known as KH homology domain-containing protein 4) from animals. RIK1 interacts with rough sheath2 (RS2), which is a myb domain protein required to repress knox genes during leaf development []. BLOM7 is a RNA-binding protein involved in pre-mRNA splicing []. It has been shown to interact with SNEV (Prp19/Pso4), a splicing factor [].
Strain
Attribute String: mutant stock, spontaneous mutation
Strain
Attribute String: congenic, mutant strain, targeted mutation
Strain
Attribute String: targeted mutation, mutant stock
Strain
Attribute String: mutant stock, targeted mutation
Genotype
Symbol: Zeb1/Zeb1
Background: B6.Cg-Zeb1/Zeb1
Zygosity: ht
Has Mutant Allele: true
Publication
First Author: Wei N
Year: 2015
Journal: Cell Rep
Title: SRSF10 Plays a Role in Myoblast Differentiation and Glucose Production via Regulation of Alternative Splicing.
Volume: 13
Issue: 8
Pages: 1647-57
Protein
Organism: Mus musculus/domesticus
Length: 168  
Fragment?: true
Publication
First Author: Da G
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Structure and function of the SWIRM domain, a conserved protein module found in chromatin regulatory complexes.
Volume: 103
Issue: 7
Pages: 2057-62
Publication
First Author: Aravind L
Year: 2002
Journal: Genome Biol
Title: The SWIRM domain: a conserved module found in chromosomal proteins points to novel chromatin-modifying activities.
Volume: 3
Issue: 8
Pages: RESEARCH0039
Publication
First Author: Rugnone ML
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: LNK genes integrate light and clock signaling networks at the core of the Arabidopsis oscillator.
Volume: 110
Issue: 29
Pages: 12120-5
Publication
First Author: Ma Y
Year: 2018
Journal: Plant Cell
Title: Targeted Recruitment of the Basal Transcriptional Machinery by LNK Clock Components Controls the Circadian Rhythms of Nascent RNAs in Arabidopsis.
Volume: 30
Issue: 4
Pages: 907-924
Protein Domain
Type: Domain
Description: The SWIRM domain is a small α-helical domain of about 85 amino acid residues found in eukaryotic chromosomal proteins. It is named after the proteins SWI3, RSC8 and MOIRA in which it was first recognised. This domain mediates protein-protein interactions in the assembly of chromatin-protein complexes [, ]. The yeast SWI3 SWIRM structure revealed that it forms a four-helix globular domain containing a helix-turn-helix motif [].The SWIRM domain can be linked to different domains, such as the ZZ-type zinc finger (), the Myb DNA-binding domain (), the HORMA domain (), the amino-oxidase domain, the chromo domain (), and the JAB1/PAD1 domain.
Protein Domain
Type: Family
Description: The LNK family consists of light and clock regulated morning genes from plants. These control both the pace of circadian rhythms and the photoperiodic regulation of flowering time by promoting the expression of a subset of clock and flowering time genes in the afternoon []. The LCL domain of clock-related factor REVEILLE8 recruits LNKs to target promoters, while its MYB domain provides DNA binding specificity. In turn, LNKs interact with RNA Polymerase II and the transcript elongation FACT complex, resulting in rhythmic changes of gene expression [].
Publication
First Author: Kumar A
Year: 2001
Journal: Gene
Title: Genomic organization and characterization of the promoter region of murine GSTM2 gene.
Volume: 270
Issue: 1-2
Pages: 221-9
Publication
First Author: Mettus RV
Year: 1994
Journal: Oncogene
Title: Murine A-myb: evidence for differential splicing and tissue-specific expression.
Volume: 9
Issue: 10
Pages: 3077-86
Publication
First Author: Broccoli D
Year: 1997
Journal: Nat Genet
Title: Human telomeres contain two distinct Myb-related proteins, TRF1 and TRF2.
Volume: 17
Issue: 2
Pages: 231-5
Publication
First Author: Lederer M
Year: 2005
Journal: J Cell Sci
Title: Profilin regulates the activity of p42POP, a novel Myb-related transcription factor.
Volume: 118
Issue: Pt 2
Pages: 331-41
Publication
First Author: Mucenski ML
Year: 1988
Journal: J Virol
Title: Comparative molecular genetic analysis of lymphomas from six inbred mouse strains.
Volume: 62
Issue: 3
Pages: 839-46
Publication  
First Author: Ying W
Year: 2016
Journal: Sci Rep
Title: miR-150 regulates obesity-associated insulin resistance by controlling B cell functions.
Volume: 6
Pages: 20176
Publication
First Author: Suzuki M
Year: 2013
Journal: Mol Cell Biol
Title: Disruption of the Hbs1l-Myb locus causes hereditary persistence of fetal hemoglobin in a mouse model.
Volume: 33
Issue: 8
Pages: 1687-95
Publication
First Author: Basova P
Year: 2014
Journal: Oncogene
Title: Aggressive acute myeloid leukemia in PU.1/p53 double-mutant mice.
Volume: 33
Issue: 39
Pages: 4735-45
Publication
First Author: Wei T
Year: 2019
Journal: Oncogene
Title: YAP-dependent induction of UHMK1 supports nuclear enrichment of the oncogene MYBL2 and proliferation in liver cancer cells.
Volume: 38
Issue: 27
Pages: 5541-5550
Publication
First Author: Blaydes SM
Year: 2001
Journal: J Virol
Title: Retroviral integration at the Epi1 locus cooperates with Nf1 gene loss in the progression to acute myeloid leukemia.
Volume: 75
Issue: 19
Pages: 9427-34
Publication
First Author: Chu TY
Year: 1995
Journal: Proc Natl Sci Counc Repub China B
Title: Characterization of the promoter of the proto-oncogene c-kit.
Volume: 19
Issue: 1
Pages: 8-18
Publication
First Author: Kwon TK
Year: 1996
Journal: Gene
Title: Characterization of the murine cyclin-dependent kinase inhibitor gene p27Kip1.
Volume: 180
Issue: 1-2
Pages: 113-20
Publication
First Author: Bianchi A
Year: 1997
Journal: EMBO J
Title: TRF1 is a dimer and bends telomeric DNA.
Volume: 16
Issue: 7
Pages: 1785-94
Publication
First Author: Barr NI
Year: 1999
Journal: Mamm Genome
Title: The fit-1 common integration locus in human and mouse is closely linked to MYB.
Volume: 10
Issue: 6
Pages: 556-9
Publication
First Author: Sanghvi VR
Year: 2014
Journal: Sci Signal
Title: Characterization of a set of tumor suppressor microRNAs in T cell acute lymphoblastic leukemia.
Volume: 7
Issue: 352
Pages: ra111
Publication
First Author: Cai W
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Enhancer dependence of cell-type-specific gene expression increases with developmental age.
Volume: 117
Issue: 35
Pages: 21450-21458
Publication
First Author: Takeda R
Year: 2020
Journal: Blood
Title: HHEX promotes myeloid transformation in cooperation with mutant ASXL1.
Volume: 136
Issue: 14
Pages: 1670-1684
Publication
First Author: Whitney IE
Year: 2011
Journal: Invest Ophthalmol Vis Sci
Title: A QTL on chromosome 10 modulates cone photoreceptor number in the mouse retina.
Volume: 52
Issue: 6
Pages: 3228-36
Publication  
First Author: Man N
Year: 2021
Journal: JCI Insight
Title: p300 suppresses the transition of myelodysplastic syndromes to acute myeloid leukemia.
Volume: 6
Issue: 19
Publication
First Author: Heltemes-Harris LM
Year: 2021
Journal: Oncogene
Title: Identification of mutations that cooperate with defects in B cell transcription factors to initiate leukemia.
Volume: 40
Issue: 43
Pages: 6166-6179
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory