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Search results 1901 to 2000 out of 2158 for Notch2

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Type Details Score
Publication    
First Author: Gao G
Year: 2022
Journal: Elife
Title: Kiaa1024L/Minar2 is essential for hearing by regulating cholesterol distribution in hair bundles.
Volume: 11
GXD Expression    
Probe: MGI:7329761
Assay Type: RT-PCR
Annotation Date: 2022-08-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759726
Stage: TS26
Assay Id: MGI:7329765
Age: embryonic day 18.5
Image: 3
Specimen Label: E18.5
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7329761
Assay Type: RT-PCR
Annotation Date: 2022-08-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759727
Stage: TS27
Assay Id: MGI:7329765
Age: postnatal day 0
Image: 3
Specimen Label: P0
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7329761
Assay Type: RT-PCR
Annotation Date: 2022-08-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759728
Stage: TS28
Assay Id: MGI:7329765
Age: postnatal day 30
Image: 3
Specimen Label: P30
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:7329761
Assay Type: RT-PCR
Annotation Date: 2022-08-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284528
Stage: TS28
Assay Id: MGI:7329765
Age: postnatal day 30
Image: 3
Specimen Label: Hc
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:7329761
Assay Type: RT-PCR
Annotation Date: 2022-08-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:7329765
Age: postnatal day 30
Image: 3
Specimen Label: Cx
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:7329761
Assay Type: RT-PCR
Annotation Date: 2022-08-16
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:7329765
Age: postnatal day 30
Image: 3
Specimen Label: Li
Detected: false
Specimen Num: 6
GXD Expression    
Probe: MGI:7329761
Assay Type: RT-PCR
Annotation Date: 2022-08-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:7329765
Age: postnatal day 30
Image: 3
Specimen Label: Sp
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:7329761
Assay Type: RT-PCR
Annotation Date: 2022-08-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:7329765
Age: postnatal day 30
Image: 3
Specimen Label: Ki
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:7329761
Assay Type: RT-PCR
Annotation Date: 2022-08-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:7329765
Age: postnatal day 30
Image: 3
Specimen Label: Lu
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:4428948
Assay Type: RNA in situ
Annotation Date: 2023-10-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3270422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7540326
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:4428948
Assay Type: RNA in situ
Annotation Date: 2023-10-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7540326
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2022-08-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757227
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7329766
Age: postnatal day 1
Image: 3B
Specimen Label: 3B
Detected: true
Specimen Num: 1
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2022-08-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757227
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7329766
Age: postnatal day 1
Image: S4B
Specimen Label: S4B
Detected: true
Specimen Num: 2
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2022-08-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757227
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7329766
Age: postnatal day 1
Specimen Label: not shown
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:4882095
Assay Type: In situ reporter (knock in)
Annotation Date: 2022-08-16
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757227
Stage: TS27
Assay Id: MGI:7329767
Age: postnatal day 1
Image: 3F
Specimen Label: 3F
Detected: false
Specimen Num: 4
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2022-08-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3549627
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7329766
Age: postnatal day 1
Specimen Label: not shown
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:4882095
Assay Type: In situ reporter (knock in)
Annotation Date: 2022-08-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759727
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:7329767
Age: postnatal day 1
Image: 3C
Note: Expression in interdental cells, organ of Corti and spiral ganglion.
Specimen Label: 3C
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4882095
Assay Type: In situ reporter (knock in)
Annotation Date: 2022-08-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759727
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7329767
Age: postnatal day 1
Image: 3D
Specimen Label: 3D
Detected: true
Specimen Num: 2
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2022-08-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1906127
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7329766
Age: postnatal day 1
Image: 3B
Specimen Label: 3B
Detected: true
Specimen Num: 1
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2022-08-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1906127
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7329766
Age: postnatal day 1
Image: S4B
Specimen Label: S4B
Detected: true
Specimen Num: 2
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2022-08-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1906127
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7329766
Age: postnatal day 1
Note: Expression mainly localized in hair cells and supporting cells.
Specimen Label: not shown
Detected: true
Specimen Num: 3
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2022-08-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1906127
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7329766
Age: postnatal day 1
Note: Expression mainly localized in hair cells and supporting cells.
Specimen Label: not shown
Detected: true
Specimen Num: 3
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2022-08-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1906127
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7329766
Age: postnatal day 1
Note: Expression mainly localized in hair cells and supporting cells.
Specimen Label: not shown
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4882095
Assay Type: In situ reporter (knock in)
Annotation Date: 2022-08-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1906127
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7329767
Age: postnatal day 1
Image: 3E
Specimen Label: 3E
Detected: true
Specimen Num: 3
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2022-08-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3582727
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7329766
Age: postnatal day 1
Specimen Label: not shown
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:26364
Assay Type: RNA in situ
Annotation Date: 1999-08-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:1341059
Age: embryonic day 9.5
Image: 5A
Note: Expression in wild-type and Notch2 mutant is identical.
Specimen Label: 5A
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:26364
Assay Type: RNA in situ
Annotation Date: 1999-08-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:1341059
Age: embryonic day 9.5
Image: 5B
Note: Expression in wild-type and Notch2 mutant is identical.
Specimen Label: 5B
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:1340522
Assay Type: RNA in situ
Annotation Date: 1999-08-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:1341060
Age: embryonic day 9.5
Image: 5C
Note: Expression in wild-type and Notch2 mutant is identical.
Specimen Label: 5C
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:1340522
Assay Type: RNA in situ
Annotation Date: 1999-08-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:1341060
Age: embryonic day 9.5
Image: 5D
Note: Expression in wild-type and Notch2 mutant is identical.
Specimen Label: 5D
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:1340523
Assay Type: RNA in situ
Annotation Date: 1999-08-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:1341061
Age: embryonic day 9.5
Image: 6A
Note: Expression in wild-type and Notch2 mutant is identical.
Specimen Label: 6A
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:1340523
Assay Type: RNA in situ
Annotation Date: 1999-08-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:1341061
Age: embryonic day 9.5
Image: 6B
Note: Expression in wild-type and Notch2 mutant is identical.
Specimen Label: 6B
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:1340524
Assay Type: RNA in situ
Annotation Date: 1999-08-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:1341062
Age: embryonic day 9.5
Image: 6C
Note: Expression in wild-type and Notch2 mutant is identical.
Specimen Label: 6C
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:1340524
Assay Type: RNA in situ
Annotation Date: 1999-08-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:1341062
Age: embryonic day 9.5
Image: 6D
Note: Expression in wild-type and Notch2 mutant is identical.
Specimen Label: 6D
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:1340527
Assay Type: RNA in situ
Annotation Date: 1999-08-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:1341063
Age: embryonic day 9.5
Image: 6E
Note: Expression in wild-type and Notch2 mutant is identical.
Specimen Label: 6E
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:1340527
Assay Type: RNA in situ
Annotation Date: 1999-08-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:1341063
Age: embryonic day 9.5
Image: 6F
Note: Expression in wild-type and Notch2 mutant is identical.
Specimen Label: 6F
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:1340528
Assay Type: RNA in situ
Annotation Date: 1999-08-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:1341064
Age: embryonic day 9.5
Image: 6G
Note: Expression in wild-type and Notch2 mutant is identical.
Specimen Label: 6G
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:1340528
Assay Type: RNA in situ
Annotation Date: 1999-08-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:1341064
Age: embryonic day 9.5
Image: 6H
Note: Expression in wild-type and Notch2 mutant is identical.
Specimen Label: 6H
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:1340526
Assay Type: RNA in situ
Annotation Date: 1999-08-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:1341065
Age: embryonic day 9.5
Note: Expression in wild-type and Notch2 mutant is identical.
Specimen Label: not shown +/m
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:1340526
Assay Type: RNA in situ
Annotation Date: 1999-08-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:1341065
Age: embryonic day 9.5
Note: Expression in wild-type and Notch2 mutant is identical.
Specimen Label: not shown m/m
Detected: true
Specimen Num: 2
Allele
Name: membrane integral NOTCH2 associated receptor 1; targeted mutation 1a, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
Allele
Name: membrane integral NOTCH2 associated receptor 1; targeted mutation 1e, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
Allele
Name: membrane integral NOTCH2 associated receptor 1; targeted mutation 2a, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
Allele
Name: membrane integral NOTCH2 associated receptor 2; targeted mutation 1a, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
Allele
Name: membrane integral NOTCH2 associated receptor 2; targeted mutation 1e, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
Allele
Name: membrane integral NOTCH2 associated receptor 2; targeted mutation 2e, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
Allele
Name: membrane integral NOTCH2 associated receptor 2; targeted mutation 2a, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
Allele
Name: membrane integral NOTCH2 associated receptor 2; targeted mutation 1b, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
Allele
Name: membrane integral NOTCH2 associated receptor 1; endonuclease-mediated mutation 1, The Centre for Phenogenomics
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Allele
Name: membrane integral NOTCH2 associated receptor 1; endonuclease-mediated mutation 2, The Centre for Phenogenomics
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Allele
Name: membrane integral NOTCH2 associated receptor 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Allele
Name: membrane integral NOTCH2 associated receptor 2; endonuclease-mediated mutation 1, Cyagen Biosciences
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Publication
First Author: Bademci G
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: Mutations in MINAR2 encoding membrane integral NOTCH2-associated receptor 2 cause deafness in humans and mice.
Volume: 119
Issue: 26
Pages: e2204084119
Allele
Name: notch 2; targeted mutation 2, Raphael Kopan
Allele Type: Targeted
Attribute String: Recombinase
Allele
Name: notch 2; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Publication  
First Author: Zhu P
Year: 2015
Journal: Nat Commun
Title: C8orf4 negatively regulates self-renewal of liver cancer stem cells via suppression of NOTCH2 signalling.
Volume: 6
Pages: 7122
Allele
Name: notch 2; targeted mutation 1.1, Ernesto Canalis
Allele Type: Targeted
Attribute String: Not Specified
Allele
Name: notch 2; targeted mutation 2.1, Ernesto Canalis
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
Allele
Name: notch 2; targeted mutation 2.2, Ernesto Canalis
Allele Type: Targeted
Attribute String: Reporter
Allele
Name: notch 2; targeted mutation 1.1, Irm Hermans-Borgmeyer
Allele Type: Targeted
Attribute String: Humanized sequence
Strain
Attribute String: coisogenic, targeted mutation
Strain
Attribute String: coisogenic, mutant strain, targeted mutation
Strain
Attribute String: coisogenic, targeted mutation
Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
Strain
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
Genotype
Symbol: Minar2/Minar2
Background: C57BL/6N-Minar2/Wtsi
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Minar1/Minar1
Background: C57BL/6NCrl-Minar1/Tcp
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Minar2/Minar2
Background: involves: C57BL/6N
Zygosity: hm
Has Mutant Allele: true
Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
Publication
First Author: Isidor B
Year: 2011
Journal: Nat Genet
Title: Truncating mutations in the last exon of NOTCH2 cause a rare skeletal disorder with osteoporosis.
Volume: 43
Issue: 4
Pages: 306-8
Publication
First Author: Simpson MA
Year: 2011
Journal: Nat Genet
Title: Mutations in NOTCH2 cause Hajdu-Cheney syndrome, a disorder of severe and progressive bone loss.
Volume: 43
Issue: 4
Pages: 303-5
GO Term
GO Term
Strain
Attribute String: mutant strain, coisogenic, targeted mutation
Strain
Attribute String: mutant strain, targeted mutation
Allele
Name: notch 2; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein
Organism: Mus musculus/domesticus
Length: 722  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 686  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1247  
Fragment?: false
Genotype
Symbol: Minar2/Minar2<+>
Background: involves: C57BL/6N
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Notch2/Notch2<+>
Background: involves: 129 * 129S1/Sv * C57BL/6J
Zygosity: ht
Has Mutant Allele: true
DO Term
Genotype
Symbol: Notch2/Notch2<+>
Background: involves: 129S1/Sv * C57BL/6J
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Notch2/Notch2 Tg(BGLAP-cre)1Clem/?
Background: involves: C57BL/6J * FVB/NJ
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Notch2/Notch2<+>
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Zygosity: ht
Has Mutant Allele: true
Allele  
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 2, Bernhard Bettler
Allele Type: Targeted
Allele
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 2, Ryuichi Nishinakamura
Allele Type: Targeted
Attribute String: Conditional ready, Inserted expressed sequence
Allele
Name: transgene insertion 1, Yumiko Saga
Allele Type: Transgenic
Attribute String: Conditional ready, Inserted expressed sequence, Reporter
Allele
Name: transgene insertion 2, Yumiko Saga
Allele Type: Transgenic
Attribute String: Conditional ready, Inserted expressed sequence, Reporter
Strain
Attribute String: Not Applicable, mutant strain, targeted mutation
Allele
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Iannis Aifantis
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
Allele
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 2, Iannis Aifantis
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
Strain
Attribute String: transgenic, mutant stock
Strain
Attribute String: transgenic, mutant stock