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Search results 1901 to 2000 out of 3068 for Ret

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Type Details Score
Publication
22493062 | J:185715
First Author: Ainoya K
Year: 2012
Journal: Mol Cell Biol
Title: UG4 enhancer-driven GATA-2 and bone morphogenetic protein 4 complementation remedies the CAKUT phenotype in Gata2 hypomorphic mutant mice.
Volume: 32
Issue: 12
Pages: 2312-22
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Publication
9092472 | J:39661
First Author: Zetterström RH
Year: 1997
Journal: Science
Title: Dopamine neuron agenesis in Nurr1-deficient mice.
Volume: 276
Issue: 5310
Pages: 248-50
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Publication
20939858 | J:171024
First Author: Calmont A
Year: 2011
Journal: Neurogastroenterol Motil
Title: Absence of the vagus nerve in the stomach of Tbx1-/- mutant mice.
Volume: 23
Issue: 2
Pages: 125-30
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Publication
26658318 | J:228873
First Author: Stathopoulou A
Year: 2016
Journal: Dev Biol
Title: Inactivation of Geminin in neural crest cells affects the generation and maintenance of enteric progenitor cells, leading to enteric aganglionosis.
Volume: 409
Issue: 2
Pages: 392-405
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Publication
12482961 | J:81008
First Author: Sato A
Year: 2003
Journal: Mol Cell Biol
Title: Zinc finger protein sall2 is not essential for embryonic and kidney development.
Volume: 23
Issue: 1
Pages: 62-9
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Publication
23409123 | J:199419
First Author: Walker KA
Year: 2013
Journal: PLoS One
Title: Deletion of fibroblast growth factor receptor 2 from the peri-wolffian duct stroma leads to ureteric induction abnormalities and vesicoureteral reflux.
Volume: 8
Issue: 2
Pages: e56062
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Publication
29483821 | J:272082
First Author: Wang H
Year: 2018
Journal: Int J Biol Sci
Title: Disruption of Gen1 Causes Congenital Anomalies of the Kidney and Urinary Tract in Mice.
Volume: 14
Issue: 1
Pages: 10-20
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Publication
23413832 | J:214510
First Author: Zhang Y
Year: 2013
Journal: Neurogastroenterol Motil
Title: Zic2 is required for enteric nervous system development and neurite outgrowth: a mouse model of enteric hyperplasia and dysplasia.
Volume: 25
Issue: 6
Pages: 538-41
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Publication
23701859 | J:201549
 
First Author: Bando T
Year: 2013
Journal: Neurosci Lett
Title: Dynamic expression pattern of leucine-rich repeat neuronal protein 4 in the mouse dorsal root ganglia during development.
Volume: 548
Pages: 73-8
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Publication
11133159 | J:66912
First Author: Kuschert S
Year: 2001
Journal: Dev Biol
Title: Characterization of Pax-2 regulatory sequences that direct transgene expression in the Wolffian duct and its derivatives.
Volume: 229
Issue: 1
Pages: 128-40
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Publication
12831858 | J:84736
First Author: Tamura S
Year: 2003
Journal: Neuroscience
Title: Localization of oncostatin M receptor beta in adult and developing CNS.
Volume: 119
Issue: 4
Pages: 991-7
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Publication
21699792 | J:175558
First Author: Wang X
Year: 2011
Journal: Gastroenterology
Title: Analysis of the sacral neural crest cell contribution to the hindgut enteric nervous system in the mouse embryo.
Volume: 141
Issue: 3
Pages: 992-1002.e1-6
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Publication
30594740 | J:295041
First Author: Porokuokka LL
Year: 2019
Journal: Cell Mol Gastroenterol Hepatol
Title: Gfra1 Underexpression Causes Hirschsprung's Disease and Associated Enterocolitis in Mice.
Volume: 7
Issue: 3
Pages: 655-678
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Publication
36418415 | J:331367
First Author: Roussel J
Year: 2022
Journal: Sci Rep
Title: The autism-associated Meis2 gene is necessary for cardiac baroreflex regulation in mice.
Volume: 12
Issue: 1
Pages: 20150
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Publication
1376319 | J:1218
First Author: Ludwig T
Year: 1992
Journal: J Biol Chem
Title: Gene and pseudogene of the mouse cation-dependent mannose 6-phosphate receptor. Genomic organization, expression, and chromosomal localization.
Volume: 267
Issue: 17
Pages: 12211-9
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Publication
12591246 | J:82126
First Author: Schnabel CA
Year: 2003
Journal: Dev Biol
Title: Pbx1 regulates nephrogenesis and ureteric branching in the developing kidney.
Volume: 254
Issue: 2
Pages: 262-76
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Publication
18570257 | J:137167
First Author: Tennese AA
Year: 2008
Journal: Dev Dyn
Title: Loss of the Prader-Willi syndrome protein necdin causes defective migration, axonal outgrowth, and survival of embryonic sympathetic neurons.
Volume: 237
Issue: 7
Pages: 1935-43
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Publication
16952347 | J:115961
First Author: Fu M
Year: 2006
Journal: Dev Biol
Title: BMP signaling regulates murine enteric nervous system precursor migration, neurite fasciculation, and patterning via altered Ncam1 polysialic acid addition.
Volume: 299
Issue: 1
Pages: 137-50
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Publication
7990960 | J:21884
First Author: Stark K
Year: 1994
Journal: Nature
Title: Epithelial transformation of metanephric mesenchyme in the developing kidney regulated by Wnt-4.
Volume: 372
Issue: 6507
Pages: 679-83
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Publication
21151121 | J:170402
First Author: Guo T
Year: 2011
Journal: Nat Neurosci
Title: An evolving NGF-Hoxd1 signaling pathway mediates development of divergent neural circuits in vertebrates.
Volume: 14
Issue: 1
Pages: 31-6
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Publication
7590254 | J:30057
First Author: Dudley AT
Year: 1995
Journal: Genes Dev
Title: A requirement for bone morphogenetic protein-7 during development of the mammalian kidney and eye.
Volume: 9
Issue: 22
Pages: 2795-807
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Publication
10579975 | J:60124
First Author: Pitera JE
Year: 1999
Journal: Gastroenterology
Title: Coordinated expression of 3' hox genes during murine embryonal gut development: an enteric Hox code.
Volume: 117
Issue: 6
Pages: 1339-51
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Publication
17396120 | J:121660
First Author: Zhong J
Year: 2007
Journal: Nat Neurosci
Title: Raf kinase signaling functions in sensory neuron differentiation and axon growth in vivo.
Volume: 10
Issue: 5
Pages: 598-607
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Publication
16319112 | J:104408
First Author: Grote D
Year: 2006
Journal: Development
Title: Pax 2/8-regulated Gata 3 expression is necessary for morphogenesis and guidance of the nephric duct in the developing kidney.
Volume: 133
Issue: 1
Pages: 53-61
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Publication
22282599 | J:316652
First Author: Sims-Lucas S
Year: 2012
Journal: J Am Soc Nephrol
Title: Ureteric morphogenesis requires Fgfr1 and Fgfr2/Frs2α signaling in the metanephric mesenchyme.
Volume: 23
Issue: 4
Pages: 607-17
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Publication
9767163 | J:50697
First Author: Labosky PA
Year: 1998
Journal: Mech Dev
Title: The winged helix transcription factor Hfh2 is expressed in neural crest and spinal cord during mouse development.
Volume: 76
Issue: 1-2
Pages: 185-90
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Publication
27480037 | J:241275
 
First Author: Reginensi A
Year: 2016
Journal: Nat Commun
Title: A critical role for NF2 and the Hippo pathway in branching morphogenesis.
Volume: 7
Pages: 12309
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Publication
29158444 | J:270523
First Author: Desgrange A
Year: 2017
Journal: Development
Title: HNF1B controls epithelial organization and cell polarity during ureteric bud branching and collecting duct morphogenesis.
Volume: 144
Issue: 24
Pages: 4704-4719
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Publication
25661788 | J:221159
First Author: Stubbusch J
Year: 2015
Journal: Dev Biol
Title: Lineage and stage specific requirement for Dicer1 in sympathetic ganglia and adrenal medulla formation and maintenance.
Volume: 400
Issue: 2
Pages: 210-23
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Publication
21035938 | J:168399
First Author: Perälä N
Year: 2011
Journal: Differentiation
Title: Sema4C-Plexin B2 signalling modulates ureteric branching in developing kidney.
Volume: 81
Issue: 2
Pages: 81-91
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Protein Domain
IPR016249 | Tyr_kinase_Ret_rcpt
Type: Family
Description: Protein phosphorylation, which plays a key role in most cellular activities, is a reversible process mediated by protein kinases and phosphoprotein phosphatases. Protein kinases catalyse the transfer of the gamma phosphate from nucleotide triphosphates (often ATP) to one or more amino acid residues in a protein substrate side chain, resulting in a conformational change affecting protein function. Phosphoprotein phosphatases catalyse the reverse process. Protein kinases fall into three broad classes, characterised with respect to substrate specificity []:Serine/threonine-protein kinasesTyrosine-protein kinasesDual specificity protein kinases (e.g. MEK - phosphorylates both Thr and Tyr on target proteins)Protein kinase function is evolutionarily conserved from Escherichia coli to human []. Protein kinases play a role in a multitude of cellular processes, including division, proliferation, apoptosis, and differentiation []. Phosphorylation usually results in a functional change of the target protein by changing enzyme activity, cellular location, or association with other proteins. The catalytic subunits of protein kinases are highly conserved, and several structures have been solved [], leading to large screens to develop kinase-specific inhibitors for the treatments of a number of diseases [].Tyrosine-protein kinases can transfer a phosphate group from ATP to a tyrosine residue in a protein. These enzymes can be divided into two main groups []:Receptor tyrosine kinases (RTK), which are transmembrane proteins involved in signal transduction; they play key roles in growth, differentiation, metabolism, adhesion, motility, death and oncogenesis []. RTKs are composed of 3 domains: an extracellular domain (binds ligand), a transmembrane (TM) domain, and an intracellular catalytic domain (phosphorylates substrate). The TM domain plays an important role in the dimerisation process necessary for signal transduction []. Cytoplasmic / non-receptor tyrosine kinases, which act as regulatory proteins, playing key roles in cell differentiation, motility, proliferation, and survival. For example, the Src-family of protein-tyrosine kinases [].This group represents a tyrosine-protein kinase, Ret receptor type.
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Publication
9448325 | J:45661
First Author: Naveilhan P
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: Expression and regulation of GFRalpha3, a glial cell line-derived neurotrophic factor family receptor.
Volume: 95
Issue: 3
Pages: 1295-300
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Publication
23283078 | J:193269
First Author: Barlow AJ
Year: 2013
Journal: Hum Mol Genet
Title: Tcof1 acts as a modifier of Pax3 during enteric nervous system development and in the pathogenesis of colonic aganglionosis.
Volume: 22
Issue: 6
Pages: 1206-17
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Publication
20213756 | J:164344
First Author: Lecoin L
Year: 2010
Journal: Dev Neurobiol
Title: MafA transcription factor identifies the early ret-expressing sensory neurons.
Volume: 70
Issue: 7
Pages: 485-97
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Publication
22228097 | J:181887
First Author: Barlow AJ
Year: 2012
Journal: Hum Mol Genet
Title: Balancing neural crest cell intrinsic processes with those of the microenvironment in Tcof1 haploinsufficient mice enables complete enteric nervous system formation.
Volume: 21
Issue: 8
Pages: 1782-93
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Publication
10357931 | J:54859
First Author: Huang EJ
Year: 1999
Journal: Development
Title: POU domain factor Brn-3a controls the differentiation and survival of trigeminal neurons by regulating Trk receptor expression.
Volume: 126
Issue: 13
Pages: 2869-82
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Publication
15204970 | J:90843
First Author: Bolon B
Year: 2004
Journal: Toxicol Pathol
Title: The candidate neuroprotective agent artemin induces autonomic neural dysplasia without preventing peripheral nerve dysfunction.
Volume: 32
Issue: 3
Pages: 275-94
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Publication
14985435 | J:97000
First Author: Morikawa Y
Year: 2004
Journal: J Neurosci
Title: Essential function of oncostatin m in nociceptive neurons of dorsal root ganglia.
Volume: 24
Issue: 8
Pages: 1941-7
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Publication
26572137 | J:228878
First Author: Kosfeld A
Year: 2016
Journal: Hum Genet
Title: Whole-exome sequencing identifies mutations of TBC1D1 encoding a Rab-GTPase-activating protein in patients with congenital anomalies of the kidneys and urinary tract (CAKUT).
Volume: 135
Issue: 1
Pages: 69-87
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Publication
10864958 | J:63175
First Author: Oppenheim RW
Year: 2000
Journal: J Neurosci
Title: Glial cell line-derived neurotrophic factor and developing mammalian motoneurons: regulation of programmed cell death among motoneuron subtypes.
Volume: 20
Issue: 13
Pages: 5001-11
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Publication
11003834 | J:64589
First Author: Baudet C
Year: 2000
Journal: Development
Title: Positive and negative interactions of GDNF, NTN and ART in developing sensory neuron subpopulations, and their collaboration with neurotrophins.
Volume: 127
Issue: 20
Pages: 4335-44
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Publication
9786421 | J:50254
First Author: Luukko K
Year: 1998
Journal: Dev Dyn
Title: Neurturin mRNA expression suggests roles in trigeminal innervation of the first branchial arch and in tooth formation.
Volume: 213
Issue: 2
Pages: 207-19
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Publication
16176945 | J:101728
First Author: Gut P
Year: 2005
Journal: Development
Title: Lack of an adrenal cortex in Sf1 mutant mice is compatible with the generation and differentiation of chromaffin cells.
Volume: 132
Issue: 20
Pages: 4611-9
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Publication
10749566 | J:61482
First Author: Miyazaki Y
Year: 2000
Journal: J Clin Invest
Title: Bone morphogenetic protein 4 regulates the budding site and elongation of the mouse ureter.
Volume: 105
Issue: 7
Pages: 863-73
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Publication
15691764 | J:96485
First Author: Basson MA
Year: 2005
Journal: Dev Cell
Title: Sprouty1 is a critical regulator of GDNF/RET-mediated kidney induction.
Volume: 8
Issue: 2
Pages: 229-39
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Publication
9165114 | J:40605
First Author: Miyamoto N
Year: 1997
Journal: Development
Title: Defects of urogenital development in mice lacking Emx2.
Volume: 124
Issue: 9
Pages: 1653-64
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Publication
8967950 | J:37450
First Author: Studer M
Year: 1996
Journal: Nature
Title: Altered segmental identity and abnormal migration of motor neurons in mice lacking Hoxb-1.
Volume: 384
Issue: 6610
Pages: 630-4
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Publication
18670373 | J:142864
First Author: Hains D
Year: 2008
Journal: Pediatr Res
Title: Role of fibroblast growth factor receptor 2 in kidney mesenchyme.
Volume: 64
Issue: 6
Pages: 592-8
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Publication
21128305 | J:167305
First Author: Sims-Lucas S
Year: 2011
Journal: Dev Dyn
Title: Fgfr1 and the IIIc isoform of Fgfr2 play critical roles in the metanephric mesenchyme mediating early inductive events in kidney development.
Volume: 240
Issue: 1
Pages: 240-9
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Publication
15893302 | J:99393
First Author: Raverot G
Year: 2005
Journal: Dev Biol
Title: Sox3 expression in undifferentiated spermatogonia is required for the progression of spermatogenesis.
Volume: 283
Issue: 1
Pages: 215-25
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Publication
29135976 | J:320346
First Author: Narla D
Year: 2017
Journal: Pediatr Res
Title: Loss of peri-Wolffian duct stromal Frs2α expression in mice leads to abnormal ureteric bud induction and vesicoureteral reflux.
Volume: 82
Issue: 6
Pages: 1022-1029
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Publication
30208315 | J:270995
First Author: Wang L
Year: 2018
Journal: Cell Rep
Title: The Atypical Kinesin KIF26A Facilitates Termination of Nociceptive Responses by Sequestering Focal Adhesion Kinase.
Volume: 24
Issue: 11
Pages: 2894-2907
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Publication
22410172 | J:184878
First Author: Soofi A
Year: 2012
Journal: Dev Biol
Title: Two novel EGFP insertion alleles reveal unique aspects of Pax2 function in embryonic and adult kidneys.
Volume: 365
Issue: 1
Pages: 241-50
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Publication
18839409 | J:208752
First Author: Hasegawa H
Year: 2008
Journal: J Comp Neurol
Title: Visualizing mechanosensory endings of TrkC-expressing neurons in HS3ST-2-hPLAP mice.
Volume: 511
Issue: 4
Pages: 543-56
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Publication
21523854 | J:172277
First Author: Mohri Y
Year: 2011
Journal: Dev Dyn
Title: Lgr4-deficient mice showed premature differentiation of ureteric bud with reduced expression of Wnt effector Lef1 and Gata3.
Volume: 240
Issue: 6
Pages: 1626-34
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Publication
7588749 | J:29812
First Author: Jones PS
Year: 1995
Journal: Eur J Biochem
Title: Chromosomal localisation, inducibility, tissue-specific expression and strain differences in three murine peroxisome-proliferator-activated-receptor genes.
Volume: 233
Issue: 1
Pages: 219-26
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Publication
10572052 | J:55785
First Author: Quaggin SE
Year: 1999
Journal: Development
Title: The basic-helix-loop-helix protein pod1 is critically important for kidney and lung organogenesis.
Volume: 126
Issue: 24
Pages: 5771-83
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Publication
15703280 | J:97218
First Author: Rossel M
Year: 2005
Journal: Development
Title: Reelin signaling is necessary for a specific step in the migration of hindbrain efferent neurons.
Volume: 132
Issue: 6
Pages: 1175-85
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Publication
10101119 | J:52756
First Author: Moore AW
Year: 1999
Journal: Development
Title: YAC complementation shows a requirement for Wt1 in the development of epicardium, adrenal gland and throughout nephrogenesis.
Volume: 126
Issue: 9
Pages: 1845-57
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Publication
21552539 | J:172359
First Author: Gonçalves A
Year: 2011
Journal: PLoS One
Title: Genetic analysis reveals an unexpected role of BMP7 in initiation of ureteric bud outgrowth in mouse embryos.
Volume: 6
Issue: 4
Pages: e19370
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Publication
12917363 | J:88191
First Author: Sun W
Year: 2003
Journal: J Neurosci
Title: Neuromuscular development after the prevention of naturally occurring neuronal death by Bax deletion.
Volume: 23
Issue: 19
Pages: 7298-310
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Publication
16018995 | J:100569
First Author: Sajithlal G
Year: 2005
Journal: Dev Biol
Title: Eya 1 acts as a critical regulator for specifying the metanephric mesenchyme.
Volume: 284
Issue: 2
Pages: 323-36
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Publication
24637293 | J:208128
First Author: Sarin S
Year: 2014
Journal: Am J Pathol
Title: β-Catenin overexpression in the metanephric mesenchyme leads to renal dysplasia genesis via cell-autonomous and non-cell-autonomous mechanisms.
Volume: 184
Issue: 5
Pages: 1395-410
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Publication
9637684 | J:48515
First Author: Britsch S
Year: 1998
Journal: Genes Dev
Title: The ErbB2 and ErbB3 receptors and their ligand, neuregulin-1, are essential for development of the sympathetic nervous system.
Volume: 12
Issue: 12
Pages: 1825-36
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Publication
16319924 | J:126634
First Author: Coppola E
Year: 2005
Journal: EMBO J
Title: Reciprocal gene replacements reveal unique functions for Phox2 genes during neural differentiation.
Volume: 24
Issue: 24
Pages: 4392-403
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Publication
22922260 | J:190742
First Author: Nagashimada M
Year: 2012
Journal: J Clin Invest
Title: Autonomic neurocristopathy-associated mutations in PHOX2B dysregulate Sox10 expression.
Volume: 122
Issue: 9
Pages: 3145-58
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Publication
18358465 | J:136068
First Author: Bridgewater D
Year: 2008
Journal: Dev Biol
Title: Canonical WNT/beta-catenin signaling is required for ureteric branching.
Volume: 317
Issue: 1
Pages: 83-94
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Publication
23993789 | J:204539
First Author: Gandhi D
Year: 2013
Journal: Dev Cell
Title: Retinoid signaling in progenitors controls specification and regeneration of the urothelium.
Volume: 26
Issue: 5
Pages: 469-482
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Publication
25678108 | J:221158
First Author: Okazawa M
Year: 2015
Journal: Dev Biol
Title: Region-specific regulation of cell proliferation by FGF receptor signaling during the Wolffian duct development.
Volume: 400
Issue: 1
Pages: 139-47
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Publication
12729564 | J:83365
First Author: Esquela AF
Year: 2003
Journal: Dev Biol
Title: Regulation of metanephric kidney development by growth/differentiation factor 11.
Volume: 257
Issue: 2
Pages: 356-70
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Publication
15872002 | J:98483
First Author: Hjerling-Leffler J
Year: 2005
Journal: Development
Title: The boundary cap: a source of neural crest stem cells that generate multiple sensory neuron subtypes.
Volume: 132
Issue: 11
Pages: 2623-32
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Publication
23641053 | J:316525
First Author: Kaku Y
Year: 2013
Journal: J Am Soc Nephrol
Title: Islet1 deletion causes kidney agenesis and hydroureter resembling CAKUT.
Volume: 24
Issue: 8
Pages: 1242-9
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Publication
36303068 | J:336177
First Author: Keeler AB
Year: 2022
Journal: Nat Neurosci
Title: A developmental atlas of somatosensory diversification and maturation in the dorsal root ganglia by single-cell mass cytometry.
Volume: 25
Issue: 11
Pages: 1543-1558
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Publication
25139858 | J:214811
First Author: Weiss AC
Year: 2014
Journal: Development
Title: Nephric duct insertion requires EphA4/EphA7 signaling from the pericloacal mesenchyme.
Volume: 141
Issue: 17
Pages: 3420-30
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Publication
16223478 | J:104942
First Author: Wang Q
Year: 2005
Journal: Dev Biol
Title: Odd-skipped related 1 (Odd 1) is an essential regulator of heart and urogenital development.
Volume: 288
Issue: 2
Pages: 582-94
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Publication
23918385 | J:200671
First Author: Economides AN
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Conditionals by inversion provide a universal method for the generation of conditional alleles.
Volume: 110
Issue: 34
Pages: E3179-88
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Publication
32715478 | J:300975
First Author: Weiss AC
Year: 2020
Journal: J Pathol
Title: Expansion of the renal capsular stroma, ureteric bud branching defects and cryptorchidism in mice with Wilms tumor 1 gene deletion in the stromal compartment of the developing kidney.
Volume: 252
Issue: 3
Pages: 290-303
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Publication
38351062 | J:345844
First Author: Guo Y
Year: 2024
Journal: Signal Transduct Target Ther
Title: Docking protein 6 (DOK6) selectively docks the neurotrophic signaling transduction to restrain peripheral neuropathy.
Volume: 9
Issue: 1
Pages: 32
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Publication
10331972 | J:54911
First Author: Fundin BT
Year: 1999
Journal: Development
Title: A rapid and dynamic regulation of GDNF-family ligands and receptors correlate with the developmental dependency of cutaneous sensory innervation.
Volume: 126
Issue: 12
Pages: 2597-610
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Publication
10844592 | J:63377
First Author: Abidari JM
Year: 2000
Journal: Kidney Int
Title: Identification of novel genes expressed during metanephric induction through single-cell library screening.
Volume: 57
Issue: 6
Pages: 2221-8
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Publication
9027502 | J:38299
First Author: Depatie C
Year: 1997
Journal: Genomics
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