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Search results 1901 to 2000 out of 3140 for Sod1

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Type Details Score
Publication
First Author: Chen S
Year: 2015
Journal: Neurosci Bull
Title: Histone deacetylase 6 delays motor neuron degeneration by ameliorating the autophagic flux defect in a transgenic mouse model of amyotrophic lateral sclerosis.
Volume: 31
Issue: 4
Pages: 459-68
Publication
First Author: Zhang X
Year: 2014
Journal: Autophagy
Title: MTOR-independent, autophagic enhancer trehalose prolongs motor neuron survival and ameliorates the autophagic flux defect in a mouse model of amyotrophic lateral sclerosis.
Volume: 10
Issue: 4
Pages: 588-602
Publication
First Author: Jablonski AM
Year: 2015
Journal: J Neurosci
Title: Loss of RAD-23 Protects Against Models of Motor Neuron Disease by Enhancing Mutant Protein Clearance.
Volume: 35
Issue: 42
Pages: 14286-306
Publication
First Author: Underwood CK
Year: 2011
Journal: Neuroimage
Title: Non-invasive diffusion tensor imaging detects white matter degeneration in the spinal cord of a mouse model of amyotrophic lateral sclerosis.
Volume: 55
Issue: 2
Pages: 455-61
Publication
First Author: Iaccarino C
Year: 2011
Journal: Neurobiol Dis
Title: Bcl2-A1 interacts with pro-caspase-3: implications for amyotrophic lateral sclerosis.
Volume: 43
Issue: 3
Pages: 642-50
Publication  
First Author: Lautenschläger J
Year: 2015
Journal: Mitochondrion
Title: Novel computer vision algorithm for the reliable analysis of organelle morphology in whole cell 3D images--A pilot study for the quantitative evaluation of mitochondrial fragmentation in amyotrophic lateral sclerosis.
Volume: 25
Pages: 49-59
Publication  
First Author: Jankowiak T
Year: 2022
Journal: Neuroscience
Title: Differential Effects of Invasive Anodal Trans-spinal Direct Current Stimulation on Monosynaptic Excitatory Postsynaptic Potentials, Ia Afferents Excitability, and Motoneuron Intrinsic Properties Between Superoxide Dismutase Type-1 Glycine to Alanine Substitution at Position 93 and Wildtype Mice.
Volume: 498
Pages: 125-143
Publication  
First Author: Imamura K
Year: 2017
Journal: Sci Transl Med
Title: The Src/c-Abl pathway is a potential therapeutic target in amyotrophic lateral sclerosis.
Volume: 9
Issue: 391
Publication  
First Author: Noh MY
Year: 2014
Journal: Neurosci Lett
Title: Erythropoietin modulates the immune-inflammatory response of a SOD1(G93A) transgenic mouse model of amyotrophic lateral sclerosis (ALS).
Volume: 574
Pages: 53-8
Publication
First Author: Gaj T
Year: 2017
Journal: Sci Adv
Title: In vivo genome editing improves motor function and extends survival in a mouse model of ALS.
Volume: 3
Issue: 12
Pages: eaar3952
Publication  
First Author: Chen SK
Year: 2023
Journal: Mol Ther Nucleic Acids
Title: Efficacy and safety of a SOD1-targeting artificial miRNA delivered by AAV9 in mice are impacted by miRNA scaffold selection.
Volume: 34
Pages: 102057
Publication  
First Author: Bonafede R
Year: 2020
Journal: Int J Mol Sci
Title: ASC-Exosomes Ameliorate the Disease Progression in SOD1(G93A) Murine Model Underlining Their Potential Therapeutic Use in Human ALS.
Volume: 21
Issue: 10
Publication
First Author: Zhang JJ
Year: 2018
Journal: CNS Neurosci Ther
Title: Repurposing carbamazepine for the treatment of amyotrophic lateral sclerosis in SOD1-G93A mouse model.
Volume: 24
Issue: 12
Pages: 1163-1174
Publication  
First Author: Hewitt BM
Year: 2018
Journal: J Neurosci Methods
Title: A novel automated rodent tracker (ART), demonstrated in a mouse model of amyotrophic lateral sclerosis.
Volume: 300
Pages: 147-156
Publication  
First Author: Cacabelos D
Year: 2016
Journal: Acta Neuropathol Commun
Title: Early and gender-specific differences in spinal cord mitochondrial function and oxidative stress markers in a mouse model of ALS.
Volume: 4
Pages: 3
Publication
First Author: Kreilaus F
Year: 2020
Journal: Genes Brain Behav
Title: Novel behavioural characteristics of the superoxide dismutase 1 G93A (SOD1(G93A) ) mouse model of amyotrophic lateral sclerosis include sex-dependent phenotypes.
Volume: 19
Issue: 2
Pages: e12604
Publication  
First Author: Dong QX
Year: 2018
Journal: Int Immunopharmacol
Title: An oligomer-specific antibody improved motor function and attenuated neuropathology in the SOD1-G93A transgenic mouse model of ALS.
Volume: 65
Pages: 413-421
Publication
First Author: Stoica L
Year: 2016
Journal: Ann Neurol
Title: Adeno-associated virus-delivered artificial microRNA extends survival and delays paralysis in an amyotrophic lateral sclerosis mouse model.
Volume: 79
Issue: 4
Pages: 687-700
Publication
First Author: Marlin E
Year: 2024
Journal: Br J Pharmacol
Title: Pharmacological inhibition of the integrated stress response accelerates disease progression in an amyotrophic lateral sclerosis mouse model.
Volume: 181
Issue: 3
Pages: 495-508
Publication
First Author: Zhang X
Year: 2019
Journal: Aging Dis
Title: Verapamil Ameliorates Motor Neuron Degeneration and Improves Lifespan in the SOD1(G93A) Mouse Model of ALS by Enhancing Autophagic Flux.
Volume: 10
Issue: 6
Pages: 1159-1173
Publication  
First Author: Wang L
Year: 2014
Journal: Neurobiol Dis
Title: Guanabenz, which enhances the unfolded protein response, ameliorates mutant SOD1-induced amyotrophic lateral sclerosis.
Volume: 71
Pages: 317-24
Publication
First Author: Gu R
Year: 2010
Journal: Biochem Biophys Res Commun
Title: Human adipose-derived stem cells enhance the glutamate uptake function of GLT1 in SOD1(G93A)-bearing astrocytes.
Volume: 393
Issue: 3
Pages: 481-6
Publication
First Author: Crosio C
Year: 2011
Journal: PLoS One
Title: Astroglial inhibition of NF-κB does not ameliorate disease onset and progression in a mouse model for amyotrophic lateral sclerosis (ALS).
Volume: 6
Issue: 3
Pages: e17187
Publication
First Author: Oh YK
Year: 2006
Journal: Neurosci Lett
Title: AIF translocates to the nucleus in the spinal motor neurons in a mouse model of ALS.
Volume: 406
Issue: 3
Pages: 205-10
Publication
First Author: Qosa H
Year: 2016
Journal: Glia
Title: Astrocytes drive upregulation of the multidrug resistance transporter ABCB1 (P-Glycoprotein) in endothelial cells of the blood-brain barrier in mutant superoxide dismutase 1-linked amyotrophic lateral sclerosis.
Volume: 64
Issue: 8
Pages: 1298-313
Publication
First Author: Leyton-Jaimes MF
Year: 2020
Journal: Sci Rep
Title: Empty mesoporous silica particles significantly delay disease progression and extend survival in a mouse model of ALS.
Volume: 10
Issue: 1
Pages: 20675
Publication  
First Author: Wang TH
Year: 2018
Journal: Neuroscience
Title: Fisetin Exerts Antioxidant and Neuroprotective Effects in Multiple Mutant hSOD1 Models of Amyotrophic Lateral Sclerosis by Activating ERK.
Volume: 379
Pages: 152-166
Publication  
First Author: Renzini A
Year: 2022
Journal: Int J Mol Sci
Title: Sex and HDAC4 Differently Affect the Pathophysiology of Amyotrophic Lateral Sclerosis in SOD1-G93A Mice.
Volume: 24
Issue: 1
Publication
First Author: Khademullah CS
Year: 2022
Journal: Sci Rep
Title: A novel assessment of fine-motor function reveals early hindlimb and detectable forelimb deficits in an experimental model of ALS.
Volume: 12
Issue: 1
Pages: 17010
Publication  
First Author: Quinlan KA
Year: 2015
Journal: Front Cell Neurosci
Title: Comparison of dendritic calcium transients in juvenile wild type and SOD1(G93A) mouse lumbar motoneurons.
Volume: 9
Pages: 139
Publication
First Author: Oono M
Year: 2014
Journal: J Neurochem
Title: Transglutaminase 2 accelerates neuroinflammation in amyotrophic lateral sclerosis through interaction with misfolded superoxide dismutase 1.
Volume: 128
Issue: 3
Pages: 403-18
Publication
First Author: Tada S
Year: 2019
Journal: Sci Rep
Title: Single injection of sustained-release prostacyclin analog ONO-1301-MS ameliorates hypoxic toxicity in the murine model of amyotrophic lateral sclerosis.
Volume: 9
Issue: 1
Pages: 5252
Publication
First Author: Schütz B
Year: 2005
Journal: Neurobiol Dis
Title: Imbalanced excitatory to inhibitory synaptic input precedes motor neuron degeneration in an animal model of amyotrophic lateral sclerosis.
Volume: 20
Issue: 1
Pages: 131-40
Publication
First Author: Sharp PS
Year: 2008
Journal: Neurobiol Dis
Title: Protective effects of heat shock protein 27 in a model of ALS occur in the early stages of disease progression.
Volume: 30
Issue: 1
Pages: 42-55
Publication
First Author: Sunyach C
Year: 2012
Journal: Neuropharmacology
Title: Olesoxime delays muscle denervation, astrogliosis, microglial activation and motoneuron death in an ALS mouse model.
Volume: 62
Issue: 7
Pages: 2346-52
Publication
First Author: Mead RJ
Year: 2011
Journal: PLoS One
Title: Optimised and rapid pre-clinical screening in the SOD1(G93A) transgenic mouse model of amyotrophic lateral sclerosis (ALS).
Volume: 6
Issue: 8
Pages: e23244
Publication
First Author: Kwak YD
Year: 2012
Journal: J Neurosci
Title: Upregulation of the E3 ligase NEDD4-1 by oxidative stress degrades IGF-1 receptor protein in neurodegeneration.
Volume: 32
Issue: 32
Pages: 10971-81
Publication
First Author: Blacher E
Year: 2019
Journal: Nature
Title: Potential roles of gut microbiome and metabolites in modulating ALS in mice.
Volume: 572
Issue: 7770
Pages: 474-480
Publication
First Author: Milanese M
Year: 2011
Journal: J Neurochem
Title: Abnormal exocytotic release of glutamate in a mouse model of amyotrophic lateral sclerosis.
Volume: 116
Issue: 6
Pages: 1028-42
Publication
First Author: Prause J
Year: 2013
Journal: Hum Mol Genet
Title: Altered localization, abnormal modification and loss of function of Sigma receptor-1 in amyotrophic lateral sclerosis.
Volume: 22
Issue: 8
Pages: 1581-600
Publication
First Author: Yamamuro-Tanabe A
Year: 2023
Journal: J Pharmacol Sci
Title: Schwann cell derived-peroxiredoxin protects motor neurons against hydrogen peroxide-induced cell death in mouse motor neuron cell line NSC-34.
Volume: 153
Issue: 2
Pages: 73-83
Publication
First Author: Atkin JD
Year: 2006
Journal: J Biol Chem
Title: Induction of the unfolded protein response in familial amyotrophic lateral sclerosis and association of protein-disulfide isomerase with superoxide dismutase 1.
Volume: 281
Issue: 40
Pages: 30152-65
Publication      
First Author: Joshi AU
Year: 2018
Journal: EMBO Mol Med
Title: Inhibition of Drp1/Fis1 interaction slows progression of amyotrophic lateral sclerosis.
Publication
First Author: Tovar-y-Romo LB
Year: 2006
Journal: Exp Neurol
Title: Cerebral neurons of transgenic ALS mice are vulnerable to glutamate release stimulation but not to increased extracellular glutamate due to transport blockade.
Volume: 199
Issue: 2
Pages: 281-90
Publication
First Author: Knippenberg S
Year: 2013
Journal: J Neuropathol Exp Neurol
Title: Altered expression of DJ-1 and PINK1 in sporadic ALS and in the SOD1(G93A) ALS mouse model.
Volume: 72
Issue: 11
Pages: 1052-61
Publication
First Author: Alexander GM
Year: 2000
Journal: J Neurochem
Title: Elevated cortical extracellular fluid glutamate in transgenic mice expressing human mutant (G93A) Cu/Zn superoxide dismutase.
Volume: 74
Issue: 4
Pages: 1666-73
Publication
First Author: Park JH
Year: 2017
Journal: Hum Mol Genet
Title: Amyotrophic lateral sclerosis-related mutant superoxide dismutase 1 aggregates inhibit 14-3-3-mediated cell survival by sequestration into the JUNQ compartment.
Volume: 26
Issue: 18
Pages: 3615-3629
Publication
First Author: Ishigaki S
Year: 2002
Journal: J Neurochem
Title: X-Linked inhibitor of apoptosis protein is involved in mutant SOD1-mediated neuronal degeneration.
Volume: 82
Issue: 3
Pages: 576-84
Publication
First Author: Bennett EJ
Year: 2014
Journal: PLoS One
Title: Early detection of motor dysfunction in the SOD1G93A mouse model of Amyotrophic Lateral Sclerosis (ALS) using home cage running wheels.
Volume: 9
Issue: 9
Pages: e107918
Publication
First Author: Steinacker P
Year: 2010
Journal: Am J Pathol
Title: Neuroprotective function of cellular prion protein in a mouse model of amyotrophic lateral sclerosis.
Volume: 176
Issue: 3
Pages: 1409-20
Publication  
First Author: Esposito E
Year: 2007
Journal: Brain Res
Title: Antioxidant strategies based on tomato-enriched food or pyruvate do not affect disease onset and survival in an animal model of amyotrophic lateral sclerosis.
Volume: 1168
Pages: 90-6
Publication
First Author: Foran E
Year: 2014
Journal: Glia
Title: Sumoylation of the astroglial glutamate transporter EAAT2 governs its intracellular compartmentalization.
Volume: 62
Issue: 8
Pages: 1241-53
Publication
First Author: Fischer LR
Year: 2004
Journal: Exp Neurol
Title: Amyotrophic lateral sclerosis is a distal axonopathy: evidence in mice and man.
Volume: 185
Issue: 2
Pages: 232-40
Publication
First Author: Lee J
Year: 2009
Journal: FASEB J
Title: Activation of Ets-2 by oxidative stress induces Bcl-xL expression and accounts for glial survival in amyotrophic lateral sclerosis.
Volume: 23
Issue: 6
Pages: 1739-49
Publication
First Author: Chung YH
Year: 2005
Journal: Brain Res
Title: Decreased expression of calretinin in the cerebral cortex and hippocampus of SOD1G93A transgenic mice.
Volume: 1035
Issue: 1
Pages: 105-9
Publication
First Author: West M
Year: 2004
Journal: J Neurochem
Title: The arachidonic acid 5-lipoxygenase inhibitor nordihydroguaiaretic acid inhibits tumor necrosis factor alpha activation of microglia and extends survival of G93A-SOD1 transgenic mice.
Volume: 91
Issue: 1
Pages: 133-43
Publication
First Author: Liu R
Year: 1998
Journal: Ann Neurol
Title: Enhanced oxygen radical production in a transgenic mouse model of familial amyotrophic lateral sclerosis.
Volume: 44
Issue: 5
Pages: 763-70
Publication
First Author: Duan C
Year: 2024
Journal: Mol Ther Nucleic Acids
Title: Intrathecal administration of a novel siRNA modality extends survival and improves motor function in the SOD1(G93A) ALS mouse model.
Volume: 35
Issue: 1
Pages: 102147
Publication  
First Author: Killoy KM
Year: 2018
Journal: Exp Neurol
Title: Decreased glutathione levels cause overt motor neuron degeneration in hSOD1WT over-expressing mice.
Volume: 302
Pages: 129-135
Publication
First Author: Chiot A
Year: 2020
Journal: Nat Neurosci
Title: Modifying macrophages at the periphery has the capacity to change microglial reactivity and to extend ALS survival.
Volume: 23
Issue: 11
Pages: 1339-1351
Publication
First Author: Endo F
Year: 2015
Journal: Cell Rep
Title: Astrocyte-derived TGF-β1 accelerates disease progression in ALS mice by interfering with the neuroprotective functions of microglia and T cells.
Volume: 11
Issue: 4
Pages: 592-604
Publication
First Author: Penndorf D
Year: 2017
Journal: PLoS One
Title: DNA strand breaks and TDP-43 mislocation are absent in the murine hSOD1G93A model of amyotrophic lateral sclerosis in vivo and in vitro.
Volume: 12
Issue: 8
Pages: e0183684
Publication
First Author: Bruijn LI
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: Elevated free nitrotyrosine levels, but not protein-bound nitrotyrosine or hydroxyl radicals, throughout amyotrophic lateral sclerosis (ALS)-like disease implicate tyrosine nitration as an aberrant in vivo property of one familial ALS-linked superoxide dismutase 1 mutant.
Volume: 94
Issue: 14
Pages: 7606-11
Publication
First Author: Han Y
Year: 2016
Journal: PLoS One
Title: Interleukin-6 Deficiency Does Not Affect Motor Neuron Disease Caused by Superoxide Dismutase 1 Mutation.
Volume: 11
Issue: 4
Pages: e0153399
Publication
First Author: Stieber A
Year: 2000
Journal: J Neurol Sci
Title: Aggregates of mutant protein appear progressively in dendrites, in periaxonal processes of oligodendrocytes, and in neuronal and astrocytic perikarya of mice expressing the SOD1(G93A) mutation of familial amyotrophic lateral sclerosis.
Volume: 177
Issue: 2
Pages: 114-23
Publication  
First Author: Yang YQ
Year: 2020
Journal: Neurobiol Dis
Title: Wild-type p53-induced phosphatase 1 down-regulation promotes apoptosis by activating the DNA damage-response pathway in amyotrophic lateral sclerosis.
Volume: 134
Pages: 104648
Publication  
First Author: Magrì B
Year: 2023
Journal: Neuropeptides
Title: Neuroprotective effect of the PACAP-ADNP axis on SOD1G93A mutant motor neuron death induced by trophic factors deprivation.
Volume: 102
Pages: 102386
Publication  
First Author: Garbuzova-Davis S
Year: 2018
Journal: Exp Neurol
Title: Transplantation of human bone marrow stem cells into symptomatic ALS mice enhances structural and functional blood-spinal cord barrier repair.
Volume: 310
Pages: 33-47
Publication
First Author: Apolloni S
Year: 2016
Journal: J Neuroinflammation
Title: Actions of the antihistaminergic clemastine on presymptomatic SOD1-G93A mice ameliorate ALS disease progression.
Volume: 13
Issue: 1
Pages: 191
Publication
First Author: Carunchio I
Year: 2008
Journal: Eur J Neurosci
Title: GAB(A) receptors present higher affinity and modified subunit composition in spinal motor neurons from a genetic model of amyotrophic lateral sclerosis.
Volume: 28
Issue: 7
Pages: 1275-85
Publication
First Author: Cunha C
Year: 2018
Journal: Mol Neurobiol
Title: Downregulated Glia Interplay and Increased miRNA-155 as Promising Markers to Track ALS at an Early Stage.
Volume: 55
Issue: 5
Pages: 4207-4224
Publication  
First Author: Enge TG
Year: 2018
Journal: Mol Cell Neurosci
Title: Assessment of metal concentrations in the SOD1G93A mouse model of amyotrophic lateral sclerosis and its potential role in muscular denervation, with particular focus on muscle tissue.
Volume: 88
Pages: 319-329
Publication  
First Author: Si Y
Year: 2018
Journal: Neurobiol Dis
Title: Muscle microRNA signatures as biomarkers of disease progression in amyotrophic lateral sclerosis.
Volume: 114
Pages: 85-94
Publication
First Author: Rao MV
Year: 2016
Journal: J Neurochem
Title: Calpastatin inhibits motor neuron death and increases survival of hSOD1(G93A) mice.
Volume: 137
Issue: 2
Pages: 253-65
Publication  
First Author: Braun MC
Year: 2019
Journal: Exp Neurol
Title: Defective daily temperature regulation in a mouse model of amyotrophic lateral sclerosis.
Volume: 311
Pages: 305-312
Publication  
First Author: Riancho J
Year: 2015
Journal: Front Cell Neurosci
Title: Neuroprotective Effect of Bexarotene in the SOD1(G93A) Mouse Model of Amyotrophic Lateral Sclerosis.
Volume: 9
Pages: 250
Publication  
First Author: Osborn TM
Year: 2018
Journal: Neurobiol Dis
Title: Increased motor neuron resilience by small molecule compounds that regulate IGF-II expression.
Volume: 110
Pages: 218-230
Publication  
First Author: Amporndanai K
Year: 2020
Journal: EBioMedicine
Title: Novel Selenium-based compounds with therapeutic potential for SOD1-linked amyotrophic lateral sclerosis.
Volume: 59
Pages: 102980
Publication
First Author: Boillée S
Year: 2006
Journal: Science
Title: Onset and progression in inherited ALS determined by motor neurons and microglia.
Volume: 312
Issue: 5778
Pages: 1389-92
Strain
Attribute String: transgenic, congenic
Publication
First Author: Amendola J
Year: 2004
Journal: Eur J Neurosci
Title: Altered sensorimotor development in a transgenic mouse model of amyotrophic lateral sclerosis.
Volume: 20
Issue: 10
Pages: 2822-6
Publication
First Author: Bories C
Year: 2007
Journal: Eur J Neurosci
Title: Early electrophysiological abnormalities in lumbar motoneurons in a transgenic mouse model of amyotrophic lateral sclerosis.
Volume: 25
Issue: 2
Pages: 451-9
Allele
Name: transgene insertion M3, Jon W Gordon
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Strain
Attribute String: congenic, mutant strain, transgenic
Strain
Attribute String: mutant strain, transgenic
Publication
First Author: Wootz H
Year: 2004
Journal: Biochem Biophys Res Commun
Title: Caspase-12 cleavage and increased oxidative stress during motoneuron degeneration in transgenic mouse model of ALS.
Volume: 322
Issue: 1
Pages: 281-6
Publication
First Author: Xu W
Year: 2004
Journal: Neuroscience
Title: Increased oxidative stress is associated with chronic intermittent hypoxia-mediated brain cortical neuronal cell apoptosis in a mouse model of sleep apnea.
Volume: 126
Issue: 2
Pages: 313-23
Publication
First Author: Kruidenier L
Year: 2003
Journal: Free Radic Biol Med
Title: Attenuated mild colonic inflammation and improved survival from severe DSS-colitis of transgenic Cu/Zn-SOD mice.
Volume: 34
Issue: 6
Pages: 753-65
Publication
First Author: Craven PA
Year: 2001
Journal: Diabetes
Title: Overexpression of Cu2+/Zn2+ superoxide dismutase protects against early diabetic glomerular injury in transgenic mice.
Volume: 50
Issue: 9
Pages: 2114-25
Strain
Attribute String: mutant stock, transgenic
Allele
Name: transgene insertion 51, Yoram Groner
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion 69, Yoram Groner
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion 1, Raymond Roos
Allele Type: Transgenic
Attribute String: Inducible, Inserted expressed sequence, Reporter
Allele
Name: transgene insertion G20, Mark E Gurney
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
Allele
Name: transgene insertion 832, Stefan L Marklund
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Strain
Attribute String: mutant stock, transgenic
Publication      
First Author: Goldstein LS
Year: 2011
Journal: MGI Direct Data Submission
Title: Direct Data Submission 2011/09/28
Strain
Attribute String: transgenic, mutant strain
Publication      
First Author: Goldstein LS
Year: 2011
Journal: MGI Direct Data Submission
Title: Direct Data Submission 2011/09/28
Allele
Name: transgene insertion A1073, Mark E Gurney
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence