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Search results 1901 to 1989 out of 1989 for Wnt4

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Type Details Score
Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
23645207 | J:228627
First Author: Gozo MC
Year: 2013
Journal: Cell Death Differ
Title: Foxc2 induces Wnt4 and Bmp4 expression during muscle regeneration and osteogenesis.
Volume: 20
Issue: 8
Pages: 1031-42
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GXD Expression
GXD Expression
     
Probe: MGI:2668507
Assay Type: RNA in situ
Annotation Date: 2003-08-08
Strength: Absent
Sex: Female
Emaps: EMAPS:1796220
Stage: TS20
Assay Id: MGI:2668557
Age: embryonic day 12.5
Specimen Label: Wnt4 +/- XX
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:2668508
Assay Type: RNA in situ
Annotation Date: 2003-08-08
Strength: Absent
Sex: Female
Emaps: EMAPS:1796220
Stage: TS20
Assay Id: MGI:2668558
Age: embryonic day 12.5
Specimen Label: Wnt4 +/- XX
Detected: false
Specimen Num: 3
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Publication
18281035 | J:164712
First Author: Yoshida T
Year: 2008
Journal: Exp Cell Res
Title: Negative regulation of the Wnt signal by MM-1 through inhibiting expression of the wnt4 gene.
Volume: 314
Issue: 6
Pages: 1217-28
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HT Experiment
E-GEOD-12905 | Transcription profiling of mouse ovaries lacking Foxl2, Wnt4 or Kit and wild type ovaries and testes
Series Id: GSE12905
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
14976223 | J:121048
First Author: Daikoku T
Year: 2004
Journal: Mol Endocrinol
Title: Uterine Msx-1 and Wnt4 signaling becomes aberrant in mice with the loss of leukemia inhibitory factor or Hoxa-10: evidence for a novel cytokine-homeobox-Wnt signaling in implantation.
Volume: 18
Issue: 5
Pages: 1238-50
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Publication
15604101 | J:95356
First Author: Kettunen P
Year: 2005
Journal: Development
Title: Coordination of trigeminal axon navigation and patterning with tooth organ formation: epithelial-mesenchymal interactions, and epithelial Wnt4 and Tgfbeta1 regulate semaphorin 3a expression in the dental mesenchyme.
Volume: 132
Issue: 2
Pages: 323-34
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Allele
Wnt4<tm3(EGFP/cre)Amc> | MGI:4359657
Name: wingless-type MMTV integration site family, member 4; targeted mutation 3, Andrew P McMahon
Allele Type: Targeted
Attribute String: Recombinase
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Allele
Wnt4<tm2(EGFP/cre/ERT2)Amc> | MGI:3845544
Name: wingless-type MMTV integration site family, member 4; targeted mutation 2, Andrew P McMahon
Allele Type: Targeted
Attribute String: Inducible, Recombinase, Reporter
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Strain
MGI:6392816 | B6.Cg-Wnt4<tm3(EGFP/cre)Amc>/J
Attribute String: targeted mutation, mutant strain, congenic
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Allele
Wnt4<em1Amc> | MGI:6197855
Name: wingless-type MMTV integration site family, member 4; endonuclease-mediated mutation 1, Andrew P McMahon
Allele Type: Endonuclease-mediated
Attribute String: Hypomorph
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HT Experiment
E-GEOD-6934 | Transcription profiling of mouse developing kidney to investigate Wnt4-dependent gene expression (GUDMAP Series_id: 13)
Series Id: GSE6934
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Allele
Gt(ROSA)26Sor<tm1(Wnt4)Bhr> | MGI:3769474
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Richard R Behringer
Allele Type: Targeted
Attribute String: Conditional ready, Inserted expressed sequence
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Strain
MGI:6392815 | B6.Cg-Wnt4<tm2(EGFP/cre/ERT2)Amc>/J
Attribute String: congenic, mutant strain, targeted mutation
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Genotype
Genotype
Symbol: Wnt4/Wnt4<+>
Background: involves: 129/Sv * 129S/SvEv * C57BL/6 * C57BL/6J
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Wnt4/Wnt4<+>
Background: involves: 129 * C57BL/6J
Zygosity: ht
Has Mutant Allele: true
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HT Experiment
GSE3650 | Expression analyses to identify genes involved in testis-specific vascular development
 
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: GEO
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Col2a1-cre)1Bhr/?
Background: involves: 129S7/SvEvBrd * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
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HT Experiment
E-GEOD-38315 | Gene expression analysis of granulosa cells from Fzd1 WT and KO mice
Series Id: GSE38315
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Genotype
Genotype
Symbol: Sox7/Sox7<+> Wnt4/Wnt4<+>
Background: involves: 129/Sv * 129S/SvEv * C57BL/6 * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Wnt4/Wnt4
Background: involves: 129S1/Sv * C57BL/6J
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Afdn/Afdn Wnt4/Wnt4<+>
Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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HT Experiment
GSE184708 | Single Cell transcriptomic atlas of mouse sex determination and gonadal differentiation
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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Genotype
Genotype
Symbol: Bax/Bax Wnt4/Wnt4
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Wnt4/Wnt4<+>
Background: involves: 129 * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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HT Experiment
E-GEOD-12942 | Foxl2 functions in sex determination and histogenesis throughout mouse ovary development, analyzed by Agilent arrays
Series Id: GSE12942
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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HT Experiment
E-GEOD-6287 | Transcription profiling of mouse microdissected kidney structures
Series Id: GSE6287
Experiment Type: transcription profiling by array
Study Type: Baseline
Source: ArrayExpress
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Publication
12944424 | -
First Author: Moeller C
Year: 2003
Journal: Development
Title: Carboxypeptidase Z (CPZ) modulates Wnt signaling and regulates the development of skeletal elements in the chicken.
Volume: 130
Issue: 21
Pages: 5103-11
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Publication
11287206 | J:69384
First Author: Novikova E
Year: 2001
Journal: Mech Dev
Title: Metallocarboxypeptidase Z is dynamically expressed in mouse development.
Volume: 102
Issue: 1-2
Pages: 259-62
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Publication
10671522 | -
First Author: Novikova EG
Year: 2000
Journal: J Biol Chem
Title: Carboxypeptidase Z is present in the regulated secretory pathway and extracellular matrix in cultured cells and in human tissues.
Volume: 275
Issue: 7
Pages: 4865-70
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Protein Domain
IPR034239 | M14_CPZ_CPD
Type: Domain
Description: This entry represents the carboxypeptidase domain (CPD) found in carboxypeptidase Z. Carboxypeptidase Z (CPZ; MEROPS identifier M14.012) belongs to subfamily M14B (N/E subfamily) of the M14 family of metallocarboxypeptidases (MCPs) []. CPZ is a secreted Zn-dependent enzyme whose biological function is largely unknown. Unlike other members of the N/E subfamily, CPZ has a bipartite structure, which consists of an N-terminal cysteine-rich domain (CRD) whose sequence is similar to Wnt-binding proteins, and a C-terminal CP catalytic domain that removes C-terminal Arg residues from substrates. CPZ is enriched in the extracellular matrix and is widely distributed during early embryogenesis [, ]. That the CRD of CPZ can bind to Wnt4 suggests that CPZ plays a role in Wnt signaling [, ].The carboxypeptidase A family can be divided into four subfamilies: M14A(carboxypeptidase A or digestive), M14B (carboxypeptidase H or regulatory), M14C (gamma-D-glutamyl-L-diamino acid peptidase I) and M14D (AGTPBP-1/Nna1-like proteins) [, ]. Members of subfamily M14B have longer C-termini than those of subfamily M14A [], and carboxypeptidase M (a member of the H family) is bound to the membrane by a glycosylphosphatidylinositol anchor, unlike the majority of the M14 family, which are soluble []. The zinc ligands have been determined as two histidines and a glutamate,and the catalytic residue has been identified as a C-terminal glutamate,but these do not form the characteristic metalloprotease HEXXH motif [, ]. Members of the carboxypeptidase A family are synthesised as inactive molecules with propeptides that must be cleaved to activate the enzyme. Structural studies of carboxypeptidases A and B reveal the propeptide to exist as a globular domain, followed by an extended α-helix; this shields the catalytic site, without specifically binding to it, while the substrate-binding site is blocked by making specific contacts [, ].
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HT Experiment
E-GEOD-6309 | Transcription profiling of mouse microdissected kidney structures - U74 platform
Series Id: GSE6309
Experiment Type: transcription profiling by array
Study Type: Baseline
Source: ArrayExpress
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HT Experiment
E-GEOD-27630 | The transcription factor Otx2 regulates choroid plexus development and function
Series Id: GSE27630
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
32814902 | J:297404
First Author: Yoshihara E
Year: 2020
Journal: Nature
Title: Immune-evasive human islet-like organoids ameliorate diabetes.
Volume: 586
Issue: 7830
Pages: 606-611
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Publication
30337651 | J:279181
First Author: Hung LY
Year: 2019
Journal: Mucosal Immunol
Title: Macrophages promote epithelial proliferation following infectious and non-infectious lung injury through a Trefoil factor 2-dependent mechanism.
Volume: 12
Issue: 1
Pages: 64-76
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Publication
10706144 | J:60227
First Author: Schubert M
Year: 2000
Journal: Dev Dyn
Title: Characterization of two amphioxus Wnt genes (AmphiWnt4 and AmphiWnt7b) with early expression in the developing central nervous system.
Volume: 217
Issue: 2
Pages: 205-15
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Publication
25260709 | J:217300
First Author: Cai C
Year: 2014
Journal: Genes Dev
Title: R-spondin1 is a novel hormone mediator for mammary stem cell self-renewal.
Volume: 28
Issue: 20
Pages: 2205-18
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Publication
34035273 | J:340383
First Author: Wang C
Year: 2021
Journal: Nat Commun
Title: In vivo partial reprogramming of myofibers promotes muscle regeneration by remodeling the stem cell niche.
Volume: 12
Issue: 1
Pages: 3094
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Smarca4/Smarca4 Wnt4/Wnt4<+>
Background: involves: 129 * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Publication
11766880 | -
First Author: Reznik SE
Year: 2001
Journal: Cell Mol Life Sci
Title: Carboxypeptidases from A to z: implications in embryonic development and Wnt binding.
Volume: 58
Issue: 12-13
Pages: 1790-804
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Publication
19898815 | J:156548
First Author: Krützfeldt J
Year: 2010
Journal: Diabetologia
Title: Regulation of wingless-type MMTV integration site family (WNT) signalling in pancreatic islets from wild-type and obese mice.
Volume: 53
Issue: 1
Pages: 123-7
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Publication
15073149 | J:89366
First Author: Mericskay M
Year: 2004
Journal: Development
Title: Wnt5a is required for proper epithelial-mesenchymal interactions in the uterus.
Volume: 131
Issue: 9
Pages: 2061-72
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Publication
26040669 | J:224465
First Author: Sun T
Year: 2015
Journal: Biol Reprod
Title: Lats1 Deletion Causes Increased Germ Cell Apoptosis and Follicular Cysts in Mouse Ovaries.
Volume: 93
Issue: 1
Pages: 22
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Publication
35471456 | J:351496
First Author: Rodriguez-Tirado C
Year: 2022
Journal: Cancer Res
Title: NR2F1 Is a Barrier to Dissemination of Early-Stage Breast Cancer Cells.
Volume: 82
Issue: 12
Pages: 2313-2326
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Publication
11784006 | J:72221
First Author: Couse JF
Year: 2001
Journal: Dev Biol
Title: Estrogen receptor-alpha knockout mice exhibit resistance to the developmental effects of neonatal diethylstilbestrol exposure on the female reproductive tract.
Volume: 238
Issue: 2
Pages: 224-38
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Publication
26093292 | J:228675
First Author: Kobayashi Y
Year: 2015
Journal: Biochem Biophys Res Commun
Title: Wnt16 regulates osteoclast differentiation in conjunction with Wnt5a.
Volume: 463
Issue: 4
Pages: 1278-83
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Publication
16839447 | J:113344
First Author: Nishinakamura R
Year: 2006
Journal: J Physiol Sci
Title: Essential roles of Sall family genes in kidney development.
Volume: 56
Issue: 2
Pages: 131-6
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Publication
19197916 | J:150901
First Author: Gonzalez G
Year: 2009
Journal: Mol Reprod Dev
Title: Dicer is required for female reproductive tract development and fertility in the mouse.
Volume: 76
Issue: 7
Pages: 678-88
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Publication
32546756 | J:297074
First Author: Abedini A
Year: 2020
Journal: Sci Rep
Title: Non-canonical WNT5a regulates Epithelial-to-Mesenchymal Transition in the mouse ovarian surface epithelium.
Volume: 10
Issue: 1
Pages: 9695
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Publication
25076121 | J:219694
First Author: Gao YR
Year: 2014
Journal: Endocrinology
Title: Androgen receptor inactivation resulted in acceleration in pubertal mammary gland growth, upregulation of ERα expression, and Wnt/β-catenin signaling in female mice.
Volume: 155
Issue: 12
Pages: 4951-63
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Publication
31988094 | J:285618
 
First Author: Teramoto M
Year: 2020
Journal: Biol Open
Title: The absence of SOX2 in the anterior foregut alters the esophagus into trachea and bronchi in both epithelial and mesenchymal components.
Volume: 9
Issue: 2
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Publication
32181934 | J:339020
First Author: Dennis EP
Year: 2020
Journal: J Bone Miner Res
Title: CRELD2 Is a Novel LRP1 Chaperone That Regulates Noncanonical WNT Signaling in Skeletal Development.
Volume: 35
Issue: 8
Pages: 1452-1469
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Publication
18446812 | J:186306
First Author: Morello R
Year: 2008
Journal: J Cell Physiol
Title: Brachy-syndactyly caused by loss of Sfrp2 function.
Volume: 217
Issue: 1
Pages: 127-37
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Publication
35854046 | J:326815
First Author: Lee SH
Year: 2022
Journal: Sci Rep
Title: Activation function 1 of progesterone receptor is required for mammary development and regulation of RANKL during pregnancy.
Volume: 12
Issue: 1
Pages: 12286
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Publication
24503540 | J:268011
 
First Author: Ventayol M
Year: 2014
Journal: Cell Death Dis
Title: miRNA let-7e targeting MMP9 is involved in adipose-derived stem cell differentiation toward epithelia.
Volume: 5
Pages: e1048
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Publication
16319116 | J:104891
First Author: Osafune K
Year: 2006
Journal: Development
Title: Identification of multipotent progenitors in the embryonic mouse kidney by a novel colony-forming assay.
Volume: 133
Issue: 1
Pages: 151-61
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Publication
15746078 | J:107473
First Author: Terra R
Year: 2005
Journal: Blood
Title: T-cell generation by lymph node resident progenitor cells.
Volume: 106
Issue: 1
Pages: 193-200
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Publication
38154558 | J:354199
First Author: Riedhammer KM
Year: 2024
Journal: Kidney Int
Title: Implication of transcription factor FOXD2 dysfunction in syndromic congenital anomalies of the kidney and urinary tract (CAKUT).
Volume: 105
Issue: 4
Pages: 844-864
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Publication
29367766 | J:261036
First Author: Russo A
Year: 2018
Journal: Oncogene
Title: PTEN loss in the fallopian tube induces hyperplasia and ovarian tumor formation.
Volume: 37
Issue: 15
Pages: 1976-1990
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Publication
31895692 | J:297934
First Author: Gu Y
Year: 2019
Journal: Aging (Albany NY)
Title: Loss of Klotho contributes to cartilage damage by derepression of canonical Wnt/β-catenin signaling in osteoarthritis mice.
Volume: 11
Issue: 24
Pages: 12793-12809
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Publication
32391984 | J:305733
First Author: Yu HF
Year: 2020
Journal: J Cell Mol Med
Title: Bmp2 regulates Serpinb6b expression via cAMP/PKA/Wnt4 pathway during uterine decidualization.
Volume: 24
Issue: 12
Pages: 7023-7033
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Publication
33721419 | J:307638
First Author: Han F
Year: 2021
Journal: Aging Cell
Title: Identification of SRY-box 30 as an age-related essential gatekeeper for male germ-cell meiosis and differentiation.
Volume: 20
Issue: 5
Pages: e13343
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Publication
31116734 | J:276930
First Author: Garcia-Moreno SA
Year: 2019
Journal: PLoS Genet
Title: CBX2 is required to stabilize the testis pathway by repressing Wnt signaling.
Volume: 15
Issue: 5
Pages: e1007895
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Publication
26956838 | J:241183
First Author: Boivin FJ
Year: 2016
Journal: J Pathol
Title: Stromal β-catenin overexpression contributes to the pathogenesis of renal dysplasia.
Volume: 239
Issue: 2
Pages: 174-85
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Publication
19237610 | J:149060
First Author: Boyer A
Year: 2009
Journal: Carcinogenesis
Title: Dysregulation of WNT/CTNNB1 and PI3K/AKT signaling in testicular stromal cells causes granulosa cell tumor of the testis.
Volume: 30
Issue: 5
Pages: 869-78
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Publication
16093361 | J:115734
First Author: Hsieh M
Year: 2005
Journal: Biol Reprod
Title: Mice null for Frizzled4 (Fzd4-/-) are infertile and exhibit impaired corpora lutea formation and function.
Volume: 73
Issue: 6
Pages: 1135-46
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Publication
24945252 | J:229651
First Author: Large MJ
Year: 2014
Journal: PLoS Genet
Title: The epidermal growth factor receptor critically regulates endometrial function during early pregnancy.
Volume: 10
Issue: 6
Pages: e1004451
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Publication
29631377 | J:273392
First Author: Vishy CE
Year: 2018
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Epimorphin regulates the intestinal stem cell niche via effects on the stromal microenvironment.
Volume: 315
Issue: 2
Pages: G185-G194
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Publication
20219888 | J:168173
First Author: Lee DK
Year: 2010
Journal: Mol Endocrinol
Title: Suppression of ERalpha activity by COUP-TFII is essential for successful implantation and decidualization.
Volume: 24
Issue: 5
Pages: 930-40
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Publication
22993382 | J:192467
First Author: Heard ME
Year: 2012
Journal: Biol Reprod
Title: The reproductive phenotype of mice null for transcription factor Krüppel-like factor 13 suggests compensatory function of family member Krüppel-like factor 9 in the peri-implantation uterus.
Volume: 87
Issue: 5
Pages: 115
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Publication
28911214 | J:341506
First Author: Camden AJ
Year: 2017
Journal: Mol Hum Reprod
Title: Growth regulation by estrogen in breast cancer 1 (GREB1) is a novel progesterone-responsive gene required for human endometrial stromal decidualization.
Volume: 23
Issue: 9
Pages: 646-653
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Protein
Q8R4V4
Organism: Mus musculus/domesticus
Length: 654  
Fragment?: false
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Publication
6887246 | -
First Author: Rees DC
Year: 1983
Journal: J Mol Biol
Title: Refined crystal structure of carboxypeptidase A at 1.54 A resolution.
Volume: 168
Issue: 2
Pages: 367-87
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Publication
1449602 | -
First Author: Osterman AL
Year: 1992
Journal: J Protein Chem
Title: Primary structure of carboxypeptidase T: delineation of functionally relevant features in Zn-carboxypeptidase family.
Volume: 11
Issue: 5
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