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Search results 19901 to 20000 out of 2418182 for a

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Type Details Score
Publication
19734893 | J:154648
First Author: Filosa A
Year: 2009
Journal: Nat Neurosci
Title: Neuron-glia communication via EphA4/ephrin-A3 modulates LTP through glial glutamate transport.
Volume: 12
Issue: 10
Pages: 1285-92
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Publication
11071923 | J:66269
First Author: Bandyopadhyay A
Year: 2000
Journal: Mol Biol Cell
Title: Fission yeast Int6 is not essential for global translation initiation, but deletion of int6(+) causes hypersensitivity to caffeine and affects spore formation.
Volume: 11
Issue: 11
Pages: 4005-18
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Publication
8645204 | J:33158
 
First Author: Conti A
Year: 1996
Journal: Biochem J
Title: Differential distribution of ryanodine receptor type 3 (RyR3) gene product in mammalian skeletal muscles.
Volume: 316 ( Pt 1)
Pages: 19-23
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Publication
24216609 | J:298176
First Author: Banning A
Year: 2014
Journal: Cell Signal
Title: Increased activity of mitogen activated protein kinase pathway in flotillin-2 knockout mouse model.
Volume: 26
Issue: 2
Pages: 198-207
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Publication
37967174 | J:342615
First Author: Malin J
Year: 2023
Journal: Sci Adv
Title: Expression of the transcription factor Klf6 by thymic epithelial cells is required for thymus development.
Volume: 9
Issue: 46
Pages: eadg8126
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Publication
35081372 | J:335796
First Author: Yeh CH
Year: 2022
Journal: Immunity
Title: Primary germinal center-resident T follicular helper cells are a physiologically distinct subset of CXCR5(hi)PD-1(hi) T follicular helper cells.
Volume: 55
Issue: 2
Pages: 272-289.e7
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Publication
33320834 | J:309610
 
First Author: Andres-Hernando A
Year: 2021
Journal: JCI Insight
Title: Vasopressin mediates fructose-induced metabolic syndrome by activating the V1b receptor.
Volume: 6
Issue: 1
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Publication
26214742 | J:233111
First Author: Dufner A
Year: 2015
Journal: Nat Immunol
Title: The ubiquitin-specific protease USP8 is critical for the development and homeostasis of T cells.
Volume: 16
Issue: 9
Pages: 950-60
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Publication
31201093 | J:282508
First Author: Camara A
Year: 2019
Journal: Immunity
Title: Lymph Node Mesenchymal and Endothelial Stromal Cells Cooperate via the RANK-RANKL Cytokine Axis to Shape the Sinusoidal Macrophage Niche.
Volume: 50
Issue: 6
Pages: 1467-1481.e6
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Publication
28611395 | J:332368
First Author: Mahmoud MM
Year: 2017
Journal: Sci Rep
Title: Shear stress induces endothelial-to-mesenchymal transition via the transcription factor Snail.
Volume: 7
Issue: 1
Pages: 3375
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Publication
28709803 | J:254537
First Author: St Leger AJ
Year: 2017
Journal: Immunity
Title: An Ocular Commensal Protects against Corneal Infection by Driving an Interleukin-17 Response from Mucosal γδ T Cells.
Volume: 47
Issue: 1
Pages: 148-158.e5
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GXD Expression
GXD Expression
   
Probe: MGI:5498694
Assay Type: RT-PCR
Annotation Date: 2013-08-01
Strength: Present
Sex: Female
Emaps: EMAPS:1775928
Stage: TS28
Assay Id: MGI:5498758
Age: postnatal
Image: 1
Specimen Label: Involuting D21, A
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:5498696
Assay Type: RT-PCR
Annotation Date: 2013-08-01
Strength: Absent
Sex: Female
Emaps: EMAPS:1775928
Stage: TS28
Assay Id: MGI:5498766
Age: postnatal
Image: 1
Specimen Label: Involuting D21, A
Detected: false
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:6492192
Assay Type: RT-PCR
Annotation Date: 2021-01-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:6500744
Age: postnatal adult
Specimen Label: sk. muscle A
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
     
Probe: MGI:3807796
Assay Type: RNA in situ
Annotation Date: 2008-09-26
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3576528
Stage: TS28
Assay Id: MGI:3807908
Age: postnatal week 6-8
Specimen Label: 5 A TAAR4
Detected: false
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:3807798
Assay Type: RNA in situ
Annotation Date: 2008-09-26
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3576528
Stage: TS28
Assay Id: MGI:3807909
Age: postnatal week 6-8
Specimen Label: 5 A TAAR5
Detected: false
Specimen Num: 5
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Publication
19995956 | J:155676
First Author: Westcott DJ
Year: 2009
Journal: J Exp Med
Title: MGL1 promotes adipose tissue inflammation and insulin resistance by regulating 7/4hi monocytes in obesity.
Volume: 206
Issue: 13
Pages: 3143-56
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Publication
14563325 | J:86182
First Author: Han A
Year: 2003
Journal: Immunity
Title: Bam32 links the B cell receptor to ERK and JNK and mediates B cell proliferation but not survival.
Volume: 19
Issue: 4
Pages: 621-32
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Publication
24819345 | J:225632
 
First Author: Osbourne A
Year: 2014
Journal: J Mol Cell Cardiol
Title: Downregulation of connexin43 by microRNA-130a in cardiomyocytes results in cardiac arrhythmias.
Volume: 74
Pages: 53-63
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Publication
22210910 | J:180748
First Author: Giangreco A
Year: 2012
Journal: J Immunol
Title: Epidermal Cadm1 expression promotes autoimmune alopecia via enhanced T cell adhesion and cytotoxicity.
Volume: 188
Issue: 3
Pages: 1514-22
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Publication
32917873 | J:297014
First Author: Volchuk A
Year: 2020
Journal: Nat Commun
Title: Indirect regulation of HMGB1 release by gasdermin D.
Volume: 11
Issue: 1
Pages: 4561
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Publication
24847082 | J:318226
First Author: Gupta A
Year: 2014
Journal: J Biol Chem
Title: Opioid receptor function is regulated by post-endocytic peptide processing.
Volume: 289
Issue: 28
Pages: 19613-26
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Publication
24668417 | J:347683
First Author: Eskilsson A
Year: 2014
Journal: J Comp Neurol
Title: Distribution of microsomal prostaglandin E synthase-1 in the mouse brain.
Volume: 522
Issue: 14
Pages: 3229-44
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Publication
1846866 | -
First Author: Sorkin A
Year: 1991
Journal: J Cell Biol
Title: Effect of receptor kinase inactivation on the rate of internalization and degradation of PDGF and the PDGF beta-receptor.
Volume: 112
Issue: 3
Pages: 469-78
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Publication
10940330 | -
 
First Author: Bacher A
Year: 2000
Journal: Annu Rev Nutr
Title: Biosynthesis of vitamin b2 (riboflavin).
Volume: 20
Pages: 153-67
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Publication
7920021 | -
First Author: Hijikata A
Year: 1994
Journal: Int Arch Allergy Immunol
Title: Antigenicity of the oligosaccharide moiety of the Japanese cedar (Cryptomeria japonica) pollen allergen, Cry jI.
Volume: 105
Issue: 2
Pages: 198-202
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Publication
29662484 | -
 
First Author: Zingoni A
Year: 2018
Journal: Front Immunol
Title: NKG2D and Its Ligands: "One for All, All for One".
Volume: 9
Pages: 476
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Publication
11904775 | -
First Author: Xu A
Year: 2002
Journal: Cell Tissue Res
Title: Novel genes expressed in subsets of chemosensory sensilla on the front legs of male Drosophila melanogaster.
Volume: 307
Issue: 3
Pages: 381-92
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Publication
15371542 | -
First Author: Kerres A
Year: 2004
Journal: Mol Biol Cell
Title: The fission yeast kinetochore component Spc7 associates with the EB1 family member Mal3 and is required for kinetochore-spindle association.
Volume: 15
Issue: 12
Pages: 5255-67
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Publication
29240881 | J:246048
First Author: Hamada S
Year: 2017
Journal: Carcinogenesis
Title: Nrf2 promotes mutant K-ras/p53-driven pancreatic carcinogenesis.
Volume: 38
Issue: 6
Pages: 661-670
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Genotype
Genotype
Symbol: Dtnbp1/Dtnbp1
Background: DBA/2J-Dtnbp1/J
Zygosity: hm
Has Mutant Allele: true
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Publication
11792852 | J:73986
First Author: Prinz M
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Lymph nodal prion replication and neuroinvasion in mice devoid of follicular dendritic cells.
Volume: 99
Issue: 2
Pages: 919-24
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GXD Expression
GXD Expression
     
Probe: MGI:7788445
Assay Type: Western blot
Annotation Date: 2024-12-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:7788471
Age: postnatal day 5
Specimen Label: A P5 WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:7788445
Assay Type: Western blot
Annotation Date: 2024-12-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:7788471
Age: postnatal day 5
Specimen Label: A P5 cKO
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:7788445
Assay Type: Western blot
Annotation Date: 2024-12-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:7788471
Age: postnatal day 21
Specimen Label: A P21 WT
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:7788445
Assay Type: Western blot
Annotation Date: 2024-12-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:7788471
Age: postnatal day 21
Specimen Label: A P21 cKO
Detected: true
Specimen Num: 4
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Publication
29372668 | J:310230
First Author: Struchtrup A
Year: 2018
Journal: Autophagy
Title: The ciliary protein RPGRIP1L governs autophagy independently of its proteasome-regulating function at the ciliary base in mouse embryonic fibroblasts.
Volume: 14
Issue: 4
Pages: 567-583
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Publication
17021040 | J:114401
First Author: Lewis A
Year: 2006
Journal: Development
Title: Epigenetic dynamics of the Kcnq1 imprinted domain in the early embryo.
Volume: 133
Issue: 21
Pages: 4203-10
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Publication
34233196 | J:330752
First Author: Uemura M
Year: 2021
Journal: Cell Rep
Title: A neurogenic microenvironment defined by excitatory-inhibitory neuronal circuits in adult dentate gyrus.
Volume: 36
Issue: 1
Pages: 109324
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Publication
- | J:135422
     
First Author: Murphy A (Regeneron Pharmaceuticals, Inc.)
Year: 2008
Journal: Personal Communication
Title: Smn1 deletion with lacZ knock in.
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Publication
31561919 | J:283592
First Author: Gribizis A
Year: 2019
Journal: Neuron
Title: Visual Cortex Gains Independence from Peripheral Drive before Eye Opening.
Volume: 104
Issue: 4
Pages: 711-723.e3
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Publication
16885339 | J:112093
First Author: Proweller A
Year: 2006
Journal: Cancer Res
Title: Impaired notch signaling promotes de novo squamous cell carcinoma formation.
Volume: 66
Issue: 15
Pages: 7438-44
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Publication
30334186 | J:294400
First Author: Medrano-Fernández A
Year: 2019
Journal: Mol Neurobiol
Title: The Epigenetic Factor CBP Is Required for the Differentiation and Function of Medial Ganglionic Eminence-Derived Interneurons.
Volume: 56
Issue: 6
Pages: 4440-4454
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Publication
35408803 | J:323198
 
First Author: Schlecht A
Year: 2022
Journal: Int J Mol Sci
Title: Transcriptional and Distributional Profiling of Microglia in Retinal Angiomatous Proliferation.
Volume: 23
Issue: 7
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Publication
28532839 | J:336825
 
First Author: Raspa M
Year: 2017
Journal: Theriogenology
Title: Dry ice is a reliable substrate for the distribution of frozen mouse spermatozoa: A multi-centric study.
Volume: 96
Pages: 49-57
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Publication
25301069 | J:259264
First Author: Skliris A
Year: 2015
Journal: Cell Death Differ
Title: Neuroprotection requires the functions of the RNA-binding protein HuR.
Volume: 22
Issue: 5
Pages: 703-18
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Publication
20643829 | J:165750
First Author: Schaefer A
Year: 2010
Journal: J Exp Med
Title: Argonaute 2 in dopamine 2 receptor-expressing neurons regulates cocaine addiction.
Volume: 207
Issue: 9
Pages: 1843-51
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Publication
33309273 | J:305299
 
First Author: Miura A
Year: 2021
Journal: Biochem Biophys Res Commun
Title: Contribution of PDGFRα lineage cells in adult mouse hematopoiesis.
Volume: 534
Pages: 186-192
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Publication
36448532 | J:331977
 
First Author: Seth A
Year: 2022
Journal: Development
Title: Loss of WNT4 in the gubernaculum causes unilateral cryptorchidism and fertility defects.
Volume: 149
Issue: 23
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Publication
31092129 | J:292339
First Author: Chen B
Year: 2019
Journal: Circ Res
Title: Macrophage Smad3 Protects the Infarcted Heart, Stimulating Phagocytosis and Regulating Inflammation.
Volume: 125
Issue: 1
Pages: 55-70
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Publication
37963894 | J:358783
First Author: Thomas A
Year: 2023
Journal: Nat Commun
Title: Superior colliculus bidirectionally modulates choice activity in frontal cortex.
Volume: 14
Issue: 1
Pages: 7358
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Publication
9582272 | J:114233
First Author: Sonnleitner A
Year: 1998
Journal: EMBO J
Title: Functional properties of the ryanodine receptor type 3 (RyR3) Ca2+ release channel.
Volume: 17
Issue: 10
Pages: 2790-8
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Publication
10782912 | J:62343
First Author: Temme A
Year: 2000
Journal: J Hepatol
Title: The extent of synchronous initiation and termination of DNA synthesis in regenerating mouse liver is dependent on connexin32 expressing gap junctions.
Volume: 32
Issue: 4
Pages: 627-35
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Publication
20386744 | J:159210
First Author: Galli A
Year: 2010
Journal: PLoS Genet
Title: Distinct roles of Hand2 in initiating polarity and posterior Shh expression during the onset of mouse limb bud development.
Volume: 6
Issue: 4
Pages: e1000901
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Protein Coding Gene
MGI:107549 | Tbca
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
17767158 | J:125640
First Author: Zhou W
Year: 2007
Journal: Nat Genet
Title: Modulation of morphogenesis by noncanonical Wnt signaling requires ATF/CREB family-mediated transcriptional activation of TGFbeta2.
Volume: 39
Issue: 10
Pages: 1225-34
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Publication
2879247 | J:12017
First Author: Martin GR
Year: 1987
Journal: Nature
Title: Nomenclature for homoeobox-containing genes.
Volume: 325
Issue: 6099
Pages: 21-2
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Publication
8095237 | J:4257
First Author: Mavilio F
Year: 1993
Journal: Eur J Biochem
Title: Regulation of vertebrate homeobox-containing genes by morphogens.
Volume: 212
Issue: 2
Pages: 273-88
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Publication
8100093 | J:13606
First Author: Krumlauf R
Year: 1993
Journal: Trends Genet
Title: Hox genes and pattern formation in the branchial region of the vertebrate head.
Volume: 9
Issue: 4
Pages: 106-12
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Publication
19172751 | -
First Author: Quivy JP
Year: 2008
Journal: Nat Struct Mol Biol
Title: The HP1-p150/CAF-1 interaction is required for pericentric heterochromatin replication and S-phase progression in mouse cells.
Volume: 15
Issue: 9
Pages: 972-9
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Publication
33058780 | J:300735
First Author: Seldin L
Year: 2020
Journal: Dev Cell
Title: DNA Damage Promotes Epithelial Hyperplasia and Fate Mis-specification via Fibroblast Inflammasome Activation.
Volume: 55
Issue: 5
Pages: 558-573.e6
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Publication
19926854 | J:155551
First Author: Solorzano C
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Selective N-acylethanolamine-hydrolyzing acid amidase inhibition reveals a key role for endogenous palmitoylethanolamide in inflammation.
Volume: 106
Issue: 49
Pages: 20966-71
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Publication
29941555 | J:263854
First Author: Pieraccioli M
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: ZNF281 inhibits neuronal differentiation and is a prognostic marker for neuroblastoma.
Volume: 115
Issue: 28
Pages: 7356-7361
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Publication
20639463 | J:172938
First Author: Meissner TB
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: NLR family member NLRC5 is a transcriptional regulator of MHC class I genes.
Volume: 107
Issue: 31
Pages: 13794-9
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Publication
16298139 | J:106886
First Author: Tohgo A
Year: 2006
Journal: Mol Cell Neurosci
Title: Impaired cerebellar functions in mutant mice lacking DNER.
Volume: 31
Issue: 2
Pages: 326-33
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Publication
24652995 | J:211680
First Author: Matsumoto A
Year: 2014
Journal: Blood
Title: p57 regulates T-cell development and prevents lymphomagenesis by balancing p53 activity and pre-TCR signaling.
Volume: 123
Issue: 22
Pages: 3429-39
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Publication
36344526 | J:346888
First Author: Sen A
Year: 2022
Journal: Nat Commun
Title: Mitochondrial membrane proteins and VPS35 orchestrate selective removal of mtDNA.
Volume: 13
Issue: 1
Pages: 6704
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Publication
20857974 | -
First Author: Saini A
Year: 2010
Journal: Biochemistry
Title: SufD and SufC ATPase activity are required for iron acquisition during in vivo Fe-S cluster formation on SufB.
Volume: 49
Issue: 43
Pages: 9402-12
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Publication
7407912 | -
First Author: Franck A
Year: 1980
Journal: Cell
Title: Nucleotide sequence of cauliflower mosaic virus DNA.
Volume: 21
Issue: 1
Pages: 285-94
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Publication
21719707 | -
First Author: Sasahara A
Year: 2011
Journal: J Biol Chem
Title: Substrate specificity of the aspartate:alanine antiporter (AspT) of Tetragenococcus halophilus in reconstituted liposomes.
Volume: 286
Issue: 33
Pages: 29044-52
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Publication
10985257 | -
First Author: Mantovani A
Year: 2000
Journal: J Leukoc Biol
Title: Macrophage-derived chemokine (MDC).
Volume: 68
Issue: 3
Pages: 400-4
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Publication
24187087 | -
First Author: Jamalli A
Year: 2014
Journal: J Bacteriol
Title: Control of expression of the RNases J1 and J2 in Bacillus subtilis.
Volume: 196
Issue: 2
Pages: 318-24
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Publication
23395900 | -
First Author: Chatterjee A
Year: 2013
Journal: EMBO J
Title: Structural insights into the regulation of cohesion establishment by Wpl1.
Volume: 32
Issue: 5
Pages: 677-87
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Publication
23738009 | -
First Author: Goepfert A
Year: 2013
Journal: PLoS One
Title: Conserved inhibitory mechanism and competent ATP binding mode for adenylyltransferases with Fic fold.
Volume: 8
Issue: 5
Pages: e64901
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Publication
12941785 | -
First Author: Asipu A
Year: 2003
Journal: Diabetes
Title: Properties of normal and mutant recombinant human ketohexokinases and implications for the pathogenesis of essential fructosuria.
Volume: 52
Issue: 9
Pages: 2426-32
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Publication
25285338 | -
First Author: Benjdia A
Year: 2014
Journal: Chem Commun (Camb)
Title: Rescuing DNA repair activity by rewiring the H-atom transfer pathway in the radical SAM enzyme, spore photoproduct lyase.
Volume: 50
Issue: 91
Pages: 14201-4
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Publication
26317403 | -
First Author: Elías-Villalobos A
Year: 2015
Journal: PLoS Pathog
Title: The Hos2 Histone Deacetylase Controls Ustilago maydis Virulence through Direct Regulation of Mating-Type Genes.
Volume: 11
Issue: 8
Pages: e1005134
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Publication
25825734 | J:220453
First Author: Shi Y
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Hedgehog signaling activates a positive feedback mechanism involving insulin-like growth factors to induce osteoblast differentiation.
Volume: 112
Issue: 15
Pages: 4678-83
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Publication
18227507 | J:131843
First Author: Jamain S
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Reduced social interaction and ultrasonic communication in a mouse model of monogenic heritable autism.
Volume: 105
Issue: 5
Pages: 1710-5
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Publication
19819227 | J:155614
First Author: Inoue A
Year: 2009
Journal: Biochem Biophys Res Commun
Title: Retinoic acid induces discrete Wnt-signaling-dependent differentiation in F9 cells.
Volume: 390
Issue: 3
Pages: 564-9
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Publication
37575185 | J:339295
First Author: Benhadda A
Year: 2023
Journal: iScience
Title: 5-HT(1A) and 5-HT(2B) receptor interaction and co-clustering regulate serotonergic neuron excitability.
Volume: 26
Issue: 8
Pages: 107401
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Protein Coding Gene
MGI:1298219 | Clec11a
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
25342469 | J:238186
First Author: Matz A
Year: 2015
Journal: Cell Death Differ
Title: Regulation of neuronal survival and morphology by the E3 ubiquitin ligase RNF157.
Volume: 22
Issue: 4
Pages: 626-42
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Publication
27683753 | J:262272
First Author: Johnston LK
Year: 2016
Journal: J Immunol
Title: IL-33 Precedes IL-5 in Regulating Eosinophil Commitment and Is Required for Eosinophil Homeostasis.
Volume: 197
Issue: 9
Pages: 3445-3453
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Publication
29424692 | J:263280
   
First Author: Monavarfeshani A
Year: 2018
Journal: Elife
Title: LRRTM1 underlies synaptic convergence in visual thalamus.
Volume: 7
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Publication
31088970 | J:276525
First Author: Ochaba J
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: IKKβ slows Huntington's disease progression in R6/1 mice.
Volume: 116
Issue: 22
Pages: 10952-10961
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Publication
17404232 | J:131942
First Author: Lai AY
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Identification of a bone marrow precursor of the earliest thymocytes in adult mouse.
Volume: 104
Issue: 15
Pages: 6311-6
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Publication
22699452 | J:192055
First Author: Sprüssel A
Year: 2012
Journal: Leukemia
Title: Lysine-specific demethylase 1 restricts hematopoietic progenitor proliferation and is essential for terminal differentiation.
Volume: 26
Issue: 9
Pages: 2039-51
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Publication
28196704 | J:296685
 
First Author: Shibata A
Year: 2017
Journal: J Autoimmun
Title: Toll-like receptor 4 antagonist TAK-242 inhibits autoinflammatory symptoms in DITRA.
Volume: 80
Pages: 28-38
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Publication
14981127 | J:88395
First Author: Ohazama A
Year: 2004
Journal: J Dent Res
Title: Opg, Rank, and Rankl in tooth development: co-ordination of odontogenesis and osteogenesis.
Volume: 83
Issue: 3
Pages: 241-4
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Publication
17126328 | J:201256
First Author: Liu A
Year: 2006
Journal: FEBS Lett
Title: Two conserved domains in PCIF1 mediate interaction with pancreatic transcription factor PDX-1.
Volume: 580
Issue: 28-29
Pages: 6701-6
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Publication
214239 | J:6060
First Author: Mayer A
Year: 1978
Journal: Cell
Title: Fv-1 regulation of lymphoma development and of thymic ecotropic and xenotropic MuLV expression in mice of the AKR/J x RF/J cross.
Volume: 15
Issue: 2
Pages: 429-35
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Publication
26087164 | J:243557
First Author: Mo A
Year: 2015
Journal: Neuron
Title: Epigenomic Signatures of Neuronal Diversity in the Mammalian Brain.
Volume: 86
Issue: 6
Pages: 1369-84
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Protein Domain
IPR004649 | RNase_H2_suA
Type: Family
Description: Whereas bacterial and archaeal RNasesH2 are active as single polypeptides, the Saccharomyces cerevisiae (Baker's yeast) homologue, Rnh2Ap, when expressed in Escherichia coli, fails to produce an active RNase H2. For RNase H2 activity three proteins are required [Rnh2Ap (Rnh201p), Ydr279p (Rnh202p) and Ylr154p (Rnh203p)]. Deletion of any one of the proteins or mutations in the catalytic site in Rnh2A leads to loss of RNase H2 activity []. RNase H2 is an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. It participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. This entry represents the catalytic chain of RNase H2, which is found as a single polypeptide in prokaryotes and is part of a three protein complex in eukaryotes. In Saccharomyces cerevisiae (Baker's yeast) it is represented by .
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Protein Domain
IPR015957 | CDtoxinA
Type: Family
Description: Escherichia coli, Haemophilus spp and Campylobacter spp. all produce a toxin that is seen to cause distension in certain cell lines [, ], which eventually disintegrate and die. This novel toxin, termed cytolethal distending toxin (cdt), has three subunits: A, B and C. Their sizes are approx. 27.7, 29.5 and 19.9kDa respectively [], and they appear to be entirely novel []. Further research on the complete toxin has revealed that it blocks the cellcycle at stage G2, through inactivation of the cyclin-dependent kinase Cdk1, and without induction of DNA breaks. This leads to multipolar abortive mitosis and micronucleation, associated with centrosomal amplification [].The roles of each subunit are unclear, but it is believed that they haveseparate roles in pathogenicity.This entry represents the A subunit.
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Publication
22573805 | J:188882
First Author: de Freitas A
Year: 2012
Journal: J Immunol
Title: Identification of TLT2 as an engulfment receptor for apoptotic cells.
Volume: 188
Issue: 12
Pages: 6381-8
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Publication
21980488 | J:274492
First Author: Otsuka A
Year: 2011
Journal: PLoS One
Title: Requirement of interaction between mast cells and skin dendritic cells to establish contact hypersensitivity.
Volume: 6
Issue: 9
Pages: e25538
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Publication
37838005 | J:358027
 
First Author: Blondiaux A
Year: 2023
Journal: Neurobiol Dis
Title: Linking epileptic phenotypes and neural extracellular matrix remodeling signatures in mouse models of epilepsy.
Volume: 188
Pages: 106324
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Publication
38273071 | J:346029
First Author: Krishnan A
Year: 2024
Journal: Sci Rep
Title: Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) deletion in myeloid cells augments cholestatic liver injury.
Volume: 14
Issue: 1
Pages: 2145
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Publication
29073082 | J:252912
First Author: Widjaja-Adhi MAK
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Transcription factor ISX mediates the cross talk between diet and immunity.
Volume: 114
Issue: 43
Pages: 11530-11535
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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