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Search results 201 to 300 out of 389 for Abca4

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Type Details Score
Publication
18658157 | J:142322
First Author: Maeda A
Year: 2008
Journal: J Biol Chem
Title: Retinopathy in mice induced by disrupted all-trans-retinal clearance.
Volume: 283
Issue: 39
Pages: 26684-93
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Publication
24231350 | J:207755
First Author: Chen Y
Year: 2013
Journal: J Clin Invest
Title: Systems pharmacology identifies drug targets for Stargardt disease-associated retinal degeneration.
Volume: 123
Issue: 12
Pages: 5119-34
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Publication
34161819 | J:331433
 
First Author: Arunkumar R
Year: 2021
Journal: Exp Eye Res
Title: Lutein and zeaxanthin reduce A2E and iso-A2E levels and improve visual performance in Abca4(-/-)/Bco2(-/-) double knockout mice.
Volume: 209
Pages: 108680
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Publication
24726920 | J:229872
 
First Author: Sawada O
Year: 2014
Journal: Exp Eye Res
Title: All-trans-retinal induces Bax activation via DNA damage to mediate retinal cell apoptosis.
Volume: 123
Pages: 27-36
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Publication
33154094 | J:331629
First Author: Ortega JT
Year: 2021
Journal: Mol Pharmacol
Title: Protective Effects of Flavonoids in Acute Models of Light-Induced Retinal Degeneration.
Volume: 99
Issue: 1
Pages: 60-77
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Publication
31073029 | J:280810
First Author: Getter T
Year: 2019
Journal: J Biol Chem
Title: The selective estrogen receptor modulator raloxifene mitigates the effect of all-trans-retinal toxicity in photoreceptor degeneration.
Volume: 294
Issue: 24
Pages: 9461-9475
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Publication
22184108 | J:182451
First Author: Chen Y
Year: 2012
Journal: J Biol Chem
Title: Mechanism of all-trans-retinal toxicity with implications for stargardt disease and age-related macular degeneration.
Volume: 287
Issue: 7
Pages: 5059-69
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Publication
37841588 | J:351821
First Author: Matsuyama M
Year: 2023
Journal: iScience
Title: Development of novel cytoprotective small compounds inhibiting mitochondria-dependent cell death.
Volume: 26
Issue: 10
Pages: 107916
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Publication
15277666 | J:99461
First Author: Kim SR
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Rpe65 Leu450Met variant is associated with reduced levels of the retinal pigment epithelium lipofuscin fluorophores A2E and iso-A2E.
Volume: 101
Issue: 32
Pages: 11668-72
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Publication
22220722 | J:184334
First Author: Okano K
Year: 2012
Journal: J Neurochem
Title: Retinal cone and rod photoreceptor cells exhibit differential susceptibility to light-induced damage.
Volume: 121
Issue: 1
Pages: 146-56
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Publication
26225634 | J:230948
First Author: Schur RM
Year: 2015
Journal: Invest Ophthalmol Vis Sci
Title: Manganese-Enhanced MRI for Preclinical Evaluation of Retinal Degeneration Treatments.
Volume: 56
Issue: 8
Pages: 4936-42
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Publication
29871924 | J:267104
First Author: Racz B
Year: 2018
Journal: J Biol Chem
Title: A non-retinoid antagonist of retinol-binding protein 4 rescues phenotype in a model of Stargardt disease without inhibiting the visual cycle.
Volume: 293
Issue: 29
Pages: 11574-11588
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Publication
24706818 | J:208628
First Author: Nociari MM
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Beta cyclodextrins bind, stabilize, and remove lipofuscin bisretinoids from retinal pigment epithelium.
Volume: 111
Issue: 14
Pages: E1402-8
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Publication
28395299 | J:258464
First Author: Zhao J
Year: 2017
Journal: Invest Ophthalmol Vis Sci
Title: Multimodal Fundus Imaging of Sodium Iodate-Treated Mice Informs RPE Susceptibility and Origins of Increased Fundus Autofluorescence.
Volume: 58
Issue: 4
Pages: 2152-2159
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Publication
26075817 | J:225430
First Author: Zhang J
Year: 2015
Journal: J Clin Invest
Title: Molecular pharmacodynamics of emixustat in protection against retinal degeneration.
Volume: 125
Issue: 7
Pages: 2781-94
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Publication
34863682 | J:319666
 
First Author: Tao L
Year: 2022
Journal: Exp Eye Res
Title: Repressing c-Jun N-terminal kinase signaling mitigates retinal pigment epithelium degeneration in mice with failure to clear all-trans-retinal.
Volume: 214
Pages: 108877
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Publication
28192797 | J:257639
First Author: Zhao J
Year: 2017
Journal: Invest Ophthalmol Vis Sci
Title: Aberrant Buildup of All-Trans-Retinal Dimer, a Nonpyridinium Bisretinoid Lipofuscin Fluorophore, Contributes to the Degeneration of the Retinal Pigment Epithelium.
Volume: 58
Issue: 2
Pages: 1063-1075
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Publication
24712709 | J:213619
First Author: Wu Y
Year: 2014
Journal: Biochem J
Title: Retinal metabolism in humans induces the formation of an unprecedented lipofuscin fluorophore 'pdA2E'.
Volume: 460
Issue: 3
Pages: 343-52
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Publication
9054934 | J:38700
First Author: Allikmets R
Year: 1997
Journal: Nat Genet
Title: A photoreceptor cell-specific ATP-binding transporter gene (ABCR) is mutated in recessive Stargardt macular dystrophy.
Volume: 15
Issue: 3
Pages: 236-46
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Publication
29686088 | J:262070
First Author: Ueda K
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Iron promotes oxidative cell death caused by bisretinoids of retina.
Volume: 115
Issue: 19
Pages: 4963-4968
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Publication
29602770 | J:261487
First Author: Parmar T
Year: 2018
Journal: J Immunol
Title: Lipocalin 2 Plays an Important Role in Regulating Inflammation in Retinal Degeneration.
Volume: 200
Issue: 9
Pages: 3128-3141
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Publication
27875314 | J:237618
First Author: Palczewska G
Year: 2016
Journal: J Biol Chem
Title: Receptor MER Tyrosine Kinase Proto-oncogene (MERTK) Is Not Required for Transfer of Bis-retinoids to the Retinal Pigmented Epithelium.
Volume: 291
Issue: 52
Pages: 26937-26949
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Publication
27315541 | J:254616
First Author: Parmar T
Year: 2016
Journal: Invest Ophthalmol Vis Sci
Title: Acute Stress Responses Are Early Molecular Events of Retinal Degeneration in Abca4-/-Rdh8-/- Mice After Light Exposure.
Volume: 57
Issue: 7
Pages: 3257-67
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Publication
26400086 | J:226547
First Author: Zhou J
Year: 2015
Journal: J Biol Chem
Title: Correlations between Photodegradation of Bisretinoid Constituents of Retina and Dicarbonyl Adduct Deposition.
Volume: 290
Issue: 45
Pages: 27215-27
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Publication
34847075 | J:318826
 
First Author: Boguslawski J
Year: 2022
Journal: J Clin Invest
Title: In vivo imaging of the human eye using a 2-photon-excited fluorescence scanning laser ophthalmoscope.
Volume: 132
Issue: 2
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Publication
19494204 | J:154536
First Author: Maeda T
Year: 2009
Journal: Invest Ophthalmol Vis Sci
Title: Evaluation of potential therapies for a mouse model of human age-related macular degeneration caused by delayed all-trans-retinal clearance.
Volume: 50
Issue: 10
Pages: 4917-25
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Publication
29401616 | J:267644
First Author: Schur RM
Year: 2018
Journal: FASEB J
Title: New GABA modulators protect photoreceptor cells from light-induced degeneration in mouse models.
Volume: 32
Issue: 6
Pages: 3289-3300
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Publication
36553653 | J:349330
 
First Author: Mavlyutov TA
Year: 2022
Journal: Genes (Basel)
Title: Retinal Photoreceptor Protection in an AMD-Related Mouse Model by Selective Sigma-1 or Sigma-2 Receptor Modulation.
Volume: 13
Issue: 12
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Publication
30185665 | J:282073
 
First Author: Palczewska G
Year: 2018
Journal: JCI Insight
Title: Two-photon imaging of the mammalian retina with ultrafast pulsing laser.
Volume: 3
Issue: 17
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Publication
20436469 | J:166569
First Author: Beaty TH
Year: 2010
Journal: Nat Genet
Title: A genome-wide association study of cleft lip with and without cleft palate identifies risk variants near MAFB and ABCA4.
Volume: 42
Issue: 6
Pages: 525-9
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Publication
35809434 | J:346553
 
First Author: Kim HJ
Year: 2022
Journal: Redox Biol
Title: Vitamin A aldehyde-taurine adducts function in photoreceptor cells.
Volume: 54
Pages: 102386
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Publication
22169101 | J:191520
First Author: Charbel Issa P
Year: 2012
Journal: Invest Ophthalmol Vis Sci
Title: Optimization of in vivo confocal autofluorescence imaging of the ocular fundus in mice and its application to models of human retinal degeneration.
Volume: 53
Issue: 2
Pages: 1066-75
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Publication
22572847 | J:191152
First Author: Liu J
Year: 2012
Journal: Am J Physiol Cell Physiol
Title: Cystic fibrosis transmembrane conductance regulator contributes to reacidification of alkalinized lysosomes in RPE cells.
Volume: 303
Issue: 2
Pages: C160-9
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Publication
35642742 | J:351532
First Author: Ortega JT
Year: 2022
Journal: Hum Mol Genet
Title: Chromenone derivatives as novel pharmacological chaperones for retinitis pigmentosa-linked rod opsin mutants.
Volume: 31
Issue: 20
Pages: 3439-3457
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Publication
27992460 | J:256799
First Author: Fontaine V
Year: 2016
Journal: PLoS One
Title: Norbixin Protects Retinal Pigmented Epithelium Cells and Photoreceptors against A2E-Mediated Phototoxicity In Vitro and In Vivo.
Volume: 11
Issue: 12
Pages: e0167793
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Publication
21383019 | J:172084
First Author: Shiose S
Year: 2011
Journal: J Biol Chem
Title: Toll-like receptor 3 is required for development of retinopathy caused by impaired all-trans-retinal clearance in mice.
Volume: 286
Issue: 17
Pages: 15543-55
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Publication
38983013 | J:355552
 
First Author: Zhao J
Year: 2023
Journal: Front Ophthalmol (Lausanne)
Title: Iron overload and chelation modulates bisretinoid levels in the retina.
Volume: 3
Pages: 1305864
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Publication
23572532 | J:280319
First Author: Kohno H
Year: 2013
Journal: J Biol Chem
Title: Photoreceptor proteins initiate microglial activation via Toll-like receptor 4 in retinal degeneration mediated by all-trans-retinal.
Volume: 288
Issue: 21
Pages: 15326-41
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Publication
34509473 | J:340540
First Author: Ma X
Year: 2021
Journal: J Biol Chem
Title: ADAM17 mediates ectodomain shedding of the soluble VLDL receptor fragment in the retinal epithelium.
Volume: 297
Issue: 4
Pages: 101185
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Publication
25015357 | J:230135
First Author: Flynn E
Year: 2014
Journal: Invest Ophthalmol Vis Sci
Title: Fundus autofluorescence and photoreceptor cell rosettes in mouse models.
Volume: 55
Issue: 9
Pages: 5643-52
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Publication
36693600 | J:348832
 
First Author: Ortega JT
Year: 2023
Journal: Pharmacol Res
Title: Galanin receptor 3 - A new pharmacological target in retina degeneration.
Volume: 188
Pages: 106675
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Publication
24706832 | J:208625
First Author: Maeda A
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Two-photon microscopy reveals early rod photoreceptor cell damage in light-exposed mutant mice.
Volume: 111
Issue: 14
Pages: E1428-37
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Publication
21076393 | J:167525
First Author: Palczewska G
Year: 2010
Journal: Nat Med
Title: Noninvasive multiphoton fluorescence microscopy resolves retinol and retinal condensation products in mouse eyes.
Volume: 16
Issue: 12
Pages: 1444-9
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Publication
24952647 | J:227607
First Author: Palczewska G
Year: 2014
Journal: Nat Med
Title: Noninvasive two-photon microscopy imaging of mouse retina and retinal pigment epithelium through the pupil of the eye.
Volume: 20
Issue: 7
Pages: 785-9
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Publication
18195010 | J:135257
First Author: Golczak M
Year: 2008
Journal: J Biol Chem
Title: Metabolic basis of visual cycle inhibition by retinoid and nonretinoid compounds in the vertebrate retina.
Volume: 283
Issue: 15
Pages: 9543-54
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Publication
23943788 | J:203124
First Author: Zhang Y
Year: 2014
Journal: Hum Mol Genet
Title: BBS mutations modify phenotypic expression of CEP290-related ciliopathies.
Volume: 23
Issue: 1
Pages: 40-51
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Publication
27460988 | J:259993
First Author: Chen Y
Year: 2016
Journal: Sci Signal
Title: Synergistically acting agonists and antagonists of G protein-coupled receptors prevent photoreceptor cell degeneration.
Volume: 9
Issue: 438
Pages: ra74
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Publication
24639355 | J:210001
First Author: Kohno H
Year: 2014
Journal: J Immunol
Title: CCL3 production by microglial cells modulates disease severity in murine models of retinal degeneration.
Volume: 192
Issue: 8
Pages: 3816-27
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Publication
23341467 | J:196891
First Author: Chen Y
Year: 2013
Journal: J Biol Chem
Title: Autophagy protects the retina from light-induced degeneration.
Volume: 288
Issue: 11
Pages: 7506-18
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Publication
20404157 | J:160326
First Author: Maeda A
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Palmitoylation stabilizes unliganded rod opsin.
Volume: 107
Issue: 18
Pages: 8428-33
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Publication
33139401 | J:297673
First Author: Zarebidaki F
Year: 2020
Journal: J Neurosci
Title: Disentangling the Roles of RIM and Munc13 in Synaptic Vesicle Localization and Neurotransmission.
Volume: 40
Issue: 49
Pages: 9372-9385
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UniProt Feature
UniProt Feature
Begin: 1
Description: Retinal-specific phospholipid-transporting ATPase ABCA4
Type: chain
End: 2310
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Publication
24721909 | J:209956
 
First Author: Liakath-Ali K
Year: 2014
Journal: Nat Commun
Title: Novel skin phenotypes revealed by a genome-wide mouse reverse genetic screen.
Volume: 5
Pages: 3540
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Publication
29922981 | J:274446
First Author: Wei W
Year: 2019
Journal: Mol Neurobiol
Title: Requirement of the Mowat-Wilson Syndrome Gene Zeb2 in the Differentiation and Maintenance of Non-photoreceptor Cell Types During Retinal Development.
Volume: 56
Issue: 3
Pages: 1719-1736
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Publication
25810521 | J:221341
First Author: Lun MP
Year: 2015
Journal: J Neurosci
Title: Spatially heterogeneous choroid plexus transcriptomes encode positional identity and contribute to regional CSF production.
Volume: 35
Issue: 12
Pages: 4903-16
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Publication
15163632 | J:225638
First Author: Yoshida S
Year: 2004
Journal: Hum Mol Genet
Title: Expression profiling of the developing and mature Nrl-/- mouse retina: identification of retinal disease candidates and transcriptional regulatory targets of Nrl.
Volume: 13
Issue: 14
Pages: 1487-503
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
32290105 | J:282558
 
First Author: Collin GB
Year: 2020
Journal: Cells
Title: Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss.
Volume: 9
Issue: 4
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Publication
- | J:104881
     
First Author: The RIKEN BioResource Center
Year: 2006
Journal: Unpublished
Title: Information obtained from The RIKEN BioResource Center
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Publication
- | J:175295
     
First Author: Mouse Genome Informatics and the Wellcome Trust Sanger Institute Mouse Genetics Project (MGP)
Year: 2011
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the Wellcome Trust Sanger Institute (WTSI) Mouse Resources Portal
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Publication
- | J:165964
     
First Author: Mammalian Functional Genomics Centre
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the NorCOMM project by the Mammalian Functional Genomics Centre (Mfgc), University of Manitoba
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Publication
30973865 | J:274872
First Author: Ingham NJ
Year: 2019
Journal: PLoS Biol
Title: Mouse screen reveals multiple new genes underlying mouse and human hearing loss.
Volume: 17
Issue: 4
Pages: e3000194
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Publication
- | J:342608
       
First Author: GO Central curators, GOA curators, Rhea curators
Year: 2020
Title: Automatic Gene Ontology annotation based on Rhea mapping
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Publication
14681479 | J:122989
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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HT Experiment
E-GEOD-63772 | RNA-Seq of retina and RPE/choroid tissues from wild type, Abca4 knockout and Abca4 L541P;A1038V knockin mice
Series Id: GSE63772
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: ArrayExpress
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Protein
O35600
Organism: Mus musculus/domesticus
Length: 2310  
Fragment?: false
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Protein
A0A0G2JGG8
Organism: Mus musculus/domesticus
Length: 1102  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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