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Search results 201 to 288 out of 288 for Acd

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Type Details Score
DO Term
DOID:0070023 | autosomal dominant dyskeratosis congenita 6
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Publication
12071954 | -
First Author: Kitagawa M
Year: 2002
Journal: Eur J Biochem
Title: Escherichia coli small heat shock proteins, IbpA and IbpB, protect enzymes from inactivation by heat and oxidants.
Volume: 269
Issue: 12
Pages: 2907-17
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Publication
12475175 | -
First Author: Haslbeck M
Year: 2002
Journal: Cell Mol Life Sci
Title: sHsps and their role in the chaperone network.
Volume: 59
Issue: 10
Pages: 1649-57
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Publication
16205709 | -
First Author: Haslbeck M
Year: 2005
Journal: Nat Struct Mol Biol
Title: Some like it hot: the structure and function of small heat-shock proteins.
Volume: 12
Issue: 10
Pages: 842-6
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Protein
P23927
Organism: Mus musculus/domesticus
Length: 175  
Fragment?: false
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Protein
P14602
Organism: Mus musculus/domesticus
Length: 209  
Fragment?: false
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Protein
P35385
Organism: Mus musculus/domesticus
Length: 169  
Fragment?: false
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Protein
Q52L78
Organism: Mus musculus/domesticus
Length: 175  
Fragment?: false
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Protein
Q545F4
Organism: Mus musculus/domesticus
Length: 209  
Fragment?: false
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Publication
15575808 | -
First Author: Augusteyn RC
Year: 2004
Journal: Clin Exp Optom
Title: alpha-crystallin: a review of its structure and function.
Volume: 87
Issue: 6
Pages: 356-66
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Publication
11875128 | -
First Author: Narberhaus F
Year: 2002
Journal: Microbiol Mol Biol Rev
Title: Alpha-crystallin-type heat shock proteins: socializing minichaperones in the context of a multichaperone network.
Volume: 66
Issue: 1
Pages: 64-93; table of contents
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Allele
Acd<em1Cek> | MGI:6864320
Name: adrenocortical dysplasia; endonuclease-mediated mutation 1, Catherine Keegan
Allele Type: Endonuclease-mediated
Attribute String: Humanized sequence
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Strain
MGI:6864321 | B6.Cg-Acd<em1Cek>/J
Attribute String: congenic, endonuclease-mediated mutation, mutant strain
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Publication
26787904 | -
First Author: Weiße RH
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Structure of NDP-forming Acetyl-CoA synthetase ACD1 reveals a large rearrangement for phosphoryl transfer.
Volume: 113
Issue: 5
Pages: E519-28
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Publication
11790732 | -
First Author: Musfeldt M
Year: 2002
Journal: J Bacteriol
Title: Novel type of ADP-forming acetyl coenzyme A synthetase in hyperthermophilic archaea: heterologous expression and characterization of isoenzymes from the sulfate reducer Archaeoglobus fulgidus and the methanogen Methanococcus jannaschii.
Volume: 184
Issue: 3
Pages: 636-44
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Protein Domain
IPR043938 | Ligase_CoA_dom
Type: Domain
Description: Acetyl coenzyme A (acetyl-CoA) synthetases (ACDs) were first described in Pyrococcus furiosus and then in other Archaea members as the major energy-conserving enzymes. They catalyse the reversible formation of acetate and ATP from acetyl-CoA by using ADP and phosphate and are able to use other substrates such as phenylacetyl-CoA, indoleacetyl-CoA and isobutyryl-CoA, but not succinyl-CoA. They are involved in the conversion of acetyl-CoA to acetate and in the degradation of branched-chain amino acids via branched-chain-acyl-CoA esters. There are two isoforms ACD I and II which are heterotetramers (alpha2beta2) consisting of two different subunits, alpha and beta [, , ]. Each ACD is composed of at least five subdomains with variable sequential arrangement, termed "domain shuffling", which confers a very diverse pattern of subdomain organisation within members of the ACD family.This entry represents the C-terminal domain of the Acetate--CoA ligase [ADP-forming]subunit alpha which corresponds to the ligase CoA domain and adopts a flavodoxin fold [].
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GO Term
GO:0070187 | shelterin complex
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Publication
8830684 | -
First Author: Mai X
Year: 1996
Journal: J Bacteriol
Title: Purification and characterization of two reversible and ADP-dependent acetyl coenzyme A synthetases from the hyperthermophilic archaeon Pyrococcus furiosus.
Volume: 178
Issue: 20
Pages: 5897-903
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Publication
16188326 | J:106387
First Author: Bánvölgyi A
Year: 2005
Journal: J Neuroimmunol
Title: Evidence for a novel protective role of the vanilloid TRPV1 receptor in a cutaneous contact allergic dermatitis model.
Volume: 169
Issue: 1-2
Pages: 86-96
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Publication
31027996 | J:282447
First Author: Meixiong J
Year: 2019
Journal: Immunity
Title: Activation of Mast-Cell-Expressed Mas-Related G-Protein-Coupled Receptors Drives Non-histaminergic Itch.
Volume: 50
Issue: 5
Pages: 1163-1171.e5
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Publication
29081531 | J:254768
First Author: Feng J
Year: 2017
Journal: Nat Commun
Title: Sensory TRP channels contribute differentially to skin inflammation and persistent itch.
Volume: 8
Issue: 1
Pages: 980
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Publication
24412369 | J:208822
First Author: Delaunay D
Year: 2014
Journal: Cell Rep
Title: Mitotic spindle asymmetry: a Wnt/PCP-regulated mechanism generating asymmetrical division in cortical precursors.
Volume: 6
Issue: 2
Pages: 400-14
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Publication
23906066 | J:199282
First Author: Günschmann C
Year: 2013
Journal: Dev Cell
Title: Insulin/IGF-1 controls epidermal morphogenesis via regulation of FoxO-mediated p63 inhibition.
Volume: 26
Issue: 2
Pages: 176-87
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Publication
27184845 | J:269851
First Author: Dainichi T
Year: 2016
Journal: Cell Rep
Title: PDK1 Is a Regulator of Epidermal Differentiation that Activates and Organizes Asymmetric Cell Division.
Volume: 15
Issue: 8
Pages: 1615-23
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Publication
21098114 | J:166997
First Author: Poulson ND
Year: 2010
Journal: J Cell Biol
Title: Robust control of mitotic spindle orientation in the developing epidermis.
Volume: 191
Issue: 5
Pages: 915-22
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Publication
28095473 | J:248289
First Author: Wölwer CB
Year: 2017
Journal: PLoS One
Title: The Asymmetric Cell Division Regulators Par3, Scribble and Pins/Gpsm2 Are Not Essential for Erythroid Development or Enucleation.
Volume: 12
Issue: 1
Pages: e0170295
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Publication
26370500 | J:227554
First Author: Pham K
Year: 2015
Journal: J Cell Biol
Title: Asymmetric cell division during T cell development controls downstream fate.
Volume: 210
Issue: 6
Pages: 933-50
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Publication
19924818 | J:154365
First Author: Mikedis MM
Year: 2009
Journal: Dev Dyn
Title: Collagen type IV and Perlecan exhibit dynamic localization in the Allantoic Core Domain, a putative stem cell niche in the murine allantois.
Volume: 238
Issue: 12
Pages: 3193-204
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Publication
30146478 | J:273029
First Author: Mochizuki Y
Year: 2018
Journal: Dev Cell
Title: Combinatorial CRISPR/Cas9 Approach to Elucidate a Far-Upstream Enhancer Complex for Tissue-Specific Sox9 Expression.
Volume: 46
Issue: 6
Pages: 794-806.e6
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Publication
16418502 | -
First Author: Yang CP
Year: 2006
Journal: Nucleic Acids Res
Title: Saccharomyces cerevisiae Est3p dimerizes in vitro and dimerization contributes to efficient telomere replication in vivo.
Volume: 34
Issue: 2
Pages: 407-16
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Publication
16884717 | -
First Author: Sharanov YS
Year: 2006
Journal: FEBS Lett
Title: Saccharomyces cerevisiae telomerase subunit Est3p binds DNA and RNA and stimulates unwinding of RNA/DNA heteroduplexes.
Volume: 580
Issue: 19
Pages: 4683-90
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Publication
20884318 | -
First Author: Shubernetskaya O
Year: 2011
Journal: Biochimie
Title: Yeast telomerase protein Est3 is a novel type of GTPase.
Volume: 93
Issue: 2
Pages: 202-6
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Publication
15231715 | -
First Author: Ye JZ
Year: 2004
Journal: Genes Dev
Title: POT1-interacting protein PIP1: a telomere length regulator that recruits POT1 to the TIN2/TRF1 complex.
Volume: 18
Issue: 14
Pages: 1649-54
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Publication
22965356 | -
First Author: Armanios M
Year: 2012
Journal: Nat Rev Genet
Title: The telomere syndromes.
Volume: 13
Issue: 10
Pages: 693-704
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Publication
20231318 | J:157894
First Author: Zaug AJ
Year: 2010
Journal: Genes Dev
Title: Functional interaction between telomere protein TPP1 and telomerase.
Volume: 24
Issue: 6
Pages: 613-22
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Publication
22898822 | -
First Author: Durand E
Year: 2012
Journal: J Biol Chem
Title: Crystal structure of the VgrG1 actin cross-linking domain of the Vibrio cholerae type VI secretion system.
Volume: 287
Issue: 45
Pages: 38190-9
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Publication
19656298 | -
First Author: Geissler B
Year: 2009
Journal: Mol Microbiol
Title: Genetic determination of essential residues of the Vibrio cholerae actin cross-linking domain reveals functional similarity with glutamine synthetases.
Volume: 73
Issue: 5
Pages: 858-68
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Protein Domain
IPR032074 | ACD_dom
Type: Domain
Description: Actin cross-linking domains (ACDs) are distinct domains found in several bacterial toxins, including the Vibrio cholerae MARTX toxin. ACDs are enzyme ligases that catalyse the formation of an irreversible iso-peptide bond on two actin molecules in an ATP- and Mg/Mn(2+)-dependent manner. Cross-linking depletes the cellular pool of G-actin leading to actin cytoskeleton depolymerisation [, ].The ACD has an overall V-shape. with the active site composed of five residues in a cleft located within the two arms of the V. The first subdomain, forming the left arm of the V, is mainly composed of β-strands, while the second subdomain, forming the right arm of the V, is helical. The first subdomain is composed of a central anti-parallel β-sheet of 8 β-strands, decorated by two adjacent small β-sheets, one above the centralβ-sheet and the second below. A long helix (α1) packs against strands β7-β4-βa5 from the central β-sheet, and strand β8 from the upper β-sheet. Finally, the terminal helix α9 packs against strands β2 and β9. The second subdomain is composed of 7 α-helices (α2-α8) and does not contain any β-strands [].
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Protein Domain
IPR019437 | TPP1/Est3
Type: Domain
Description: TPP1 (Est3 in yeast) is a component of the telomerase holoenzyme (shelterin complex), involved in telomere replication. It has been demonstrated that TPP1 dimerises and binds to DNA and RNA. Furthermore, TPP1 stimulates the dissociation of RNA/DNA hetero-duplexes [, ]. Yeast telomerase protein TPP1 (Est3) is a novel type of GTPase []. The key residues in Saccharomyces cerevisiae are an Asp at residue 86 and the Arg at residue 110. The Asp is totally conserved in the family, whereas the Arg is not so well conserved. The N-terminal of TPP1 is likely to be the binding surface for TIN2, whereas the C terminus probably binds to POT1, thereby tethering POT1 to the shelterin complex []. The complex bound to telomeric DNA increases the activity and processivity of the human telomerase core enzyme, thus helping to maintain the length of the telomeres [, , ].The human shelterin complex includes six proteins: telomere repeat binding factor 1 (TRF1); TRF2, repressor/activator protein 1 (RAP1); TRF1-interacting nuclear protein 2 (TIN2); TIN2-interacting protein 1 (TPP1), also known as ACD from adrenocortical dysplasia protein; and protection of telomeres 1 (POT1) [].
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Publication
11981810 | J:76539
First Author: Townson JR
Year: 2002
Journal: Eur J Immunol
Title: Characterization of mouse CCX-CKR, a receptor for the lymphocyte-attracting chemokines TECK/mCCL25, SLC/mCCL21 and MIP-3beta/mCCL19: comparison to human CCX-CKR.
Volume: 32
Issue: 5
Pages: 1230-41
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Publication
12646655 | J:125441
First Author: Scholzen TE
Year: 2003
Journal: J Immunol
Title: Modulation of cutaneous inflammation by angiotensin-converting enzyme.
Volume: 170
Issue: 7
Pages: 3866-73
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Publication
23023706 | J:192736
First Author: Tiozzo C
Year: 2012
Journal: J Clin Invest
Title: Mesodermal Pten inactivation leads to alveolar capillary dysplasia- like phenotype.
Volume: 122
Issue: 11
Pages: 3862-72
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Publication
11805130 | J:74339
First Author: Grabbe S
Year: 2002
Journal: J Clin Invest
Title: Beta2 integrins are required for skin homing of primed T cells but not for priming naive T cells.
Volume: 109
Issue: 2
Pages: 183-92
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Publication
16456532 | J:106764
First Author: Vocanson M
Year: 2006
Journal: J Invest Dermatol
Title: CD8+ T cells are effector cells of contact dermatitis to common skin allergens in mice.
Volume: 126
Issue: 4
Pages: 815-20
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Publication
15084523 | J:118457
First Author: Scholzen TE
Year: 2004
Journal: FASEB J
Title: Cutaneous allergic contact dermatitis responses are diminished in mice deficient in neurokinin 1 receptors and augmented by neurokinin 2 receptor blockage.
Volume: 18
Issue: 9
Pages: 1007-9
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Publication
36161697 | J:333152
First Author: Fleischer MI
Year: 2022
Journal: J Thromb Haemost
Title: Protease- and cell type-specific activation of protease-activated receptor 2 in cutaneous inflammation.
Volume: 20
Issue: 12
Pages: 2823-2836
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Publication
11145711 | J:66854
First Author: Scholzen TE
Year: 2001
Journal: J Immunol
Title: Neutral endopeptidase terminates substance P-induced inflammation in allergic contact dermatitis.
Volume: 166
Issue: 2
Pages: 1285-91
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Publication
14691292 | J:124449
First Author: Schubert T
Year: 2003
Journal: Lab Invest
Title: TNF-independent development of transient anemia of chronic disease in a mouse model of protracted septic peritonitis.
Volume: 83
Issue: 12
Pages: 1743-50
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Publication
20008137 | J:156484
First Author: Kimura A
Year: 2010
Journal: Am J Pathol
Title: The absence of interleukin-6 enhanced arsenite-induced renal injury by promoting autophagy of tubular epithelial cells with aberrant extracellular signal-regulated kinase activation.
Volume: 176
Issue: 1
Pages: 40-50
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Publication
25522877 | J:220360
First Author: Nunomura S
Year: 2015
Journal: Biochem Biophys Res Commun
Title: Treatment of murine mast cells with IgEκ and protein L enhances apoptotic cell death induced by IL-3 withdrawal.
Volume: 456
Issue: 2
Pages: 700-5
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Publication
23564646 | J:206896
First Author: El Ali Z
Year: 2013
Journal: Toxicol Sci
Title: Allergic skin inflammation induced by chemical sensitizers is controlled by the transcription factor Nrf2.
Volume: 134
Issue: 1
Pages: 39-48
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Publication
37028703 | J:335451
     
First Author: Okamoto M
Year: 2023
Journal: J Invest Dermatol
Title: The Inhibition of Glycolysis in T Cells by a Jak Inhibitor Ameliorates the Pathogenesis of Allergic Contact Dermatitis in Mice.
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Publication
37180157 | J:336657
 
First Author: Hachem CE
Year: 2023
Journal: Front Immunol
Title: IL-3 produced by T cells is crucial for basophil extravasation in hapten-induced allergic contact dermatitis.
Volume: 14
Pages: 1151468
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Publication
35178048 | J:328472
 
First Author: Luo Y
Year: 2022
Journal: Front Immunol
Title: Keratin 17 Promotes T Cell Response in Allergic Contact Dermatitis by Upregulating C-C Motif Chemokine Ligand 20.
Volume: 13
Pages: 764793
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Publication
29416104 | J:263366
First Author: Ohkusu-Tsukada K
Year: 2018
Journal: Sci Rep
Title: Signs of atopic dermatitis and contact dermatitis affected by distinct H2-haplotype in the NC/Nga genetic background.
Volume: 8
Issue: 1
Pages: 2586
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Publication
37624784 | J:339569
First Author: Larson DR
Year: 2023
Journal: PLoS One
Title: Anterior chamber depth in mice is controlled by several quantitative trait loci.
Volume: 18
Issue: 8
Pages: e0286897
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Publication
37409131 | J:346960
 
First Author: Imahashi N
Year: 2023
Journal: Front Immunol
Title: MR1 deficiency enhances IL-17-mediated allergic contact dermatitis.
Volume: 14
Pages: 1215478
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Publication
30696763 | J:271502
First Author: Ameri AH
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: IL-33/regulatory T cell axis triggers the development of a tumor-promoting immune environment in chronic inflammation.
Volume: 116
Issue: 7
Pages: 2646-2651
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Publication
34601199 | J:330289
 
First Author: Almeida MS
Year: 2021
Journal: Biochem Biophys Res Commun
Title: An inhibitory immunoreceptor, Allergin-1, suppresses FITC-induced type 2 contact hypersensitivity.
Volume: 579
Pages: 146-152
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Publication
29315532 | J:263175
First Author: El Hachem C
Year: 2018
Journal: Eur J Immunol
Title: Treatment of MCPT8DTR mice with high- or low-dose diphtheria toxin leads to differential depletion of basophils and granulocyte-macrophage progenitors.
Volume: 48
Issue: 5
Pages: 861-873
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Publication
24487305 | J:210539
First Author: Liu J
Year: 2014
Journal: J Invest Dermatol
Title: IL-9 regulates allergen-specific Th1 responses in allergic contact dermatitis.
Volume: 134
Issue: 7
Pages: 1903-1911
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Publication
25344933 | J:230918
First Author: Yabe R
Year: 2015
Journal: Int Immunol
Title: CCR8 regulates contact hypersensitivity by restricting cutaneous dendritic cell migration to the draining lymph nodes.
Volume: 27
Issue: 4
Pages: 169-81
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Publication
34424262 | J:311879
First Author: Wu HJ
Year: 2021
Journal: Invest Ophthalmol Vis Sci
Title: Altered Ocular Fibrillin Microfibril Composition in Mice With a Glaucoma-Causing Mutation of Adamts10.
Volume: 62
Issue: 10
Pages: 26
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Publication
22174158 | J:215867
First Author: Ting SB
Year: 2012
Journal: Blood
Title: Asymmetric segregation and self-renewal of hematopoietic stem and progenitor cells with endocytic Ap2a2.
Volume: 119
Issue: 11
Pages: 2510-22
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Publication
1643439 | J:4030
First Author: Roth J
Year: 1992
Journal: Int Arch Allergy Immunol
Title: Expression of the calcium-binding proteins MRP8 and MRP14 by early infiltrating cells in experimental contact dermatitis.
Volume: 98
Issue: 2
Pages: 140-5
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Publication
27821781 | J:239108
First Author: Liu B
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: IL-33/ST2 signaling excites sensory neurons and mediates itch response in a mouse model of poison ivy contact allergy.
Volume: 113
Issue: 47
Pages: E7572-E7579
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Publication
30755657 | J:275491
First Author: Van Belle AB
Year: 2019
Journal: Sci Rep
Title: IL-24 contributes to skin inflammation in Para-Phenylenediamine-induced contact hypersensitivity.
Volume: 9
Issue: 1
Pages: 1852
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Publication
31959760 | J:293483
First Author: Kinzler MN
Year: 2020
Journal: Sci Rep
Title: STF-62247 and pimozide induce autophagy and autophagic cell death in mouse embryonic fibroblasts.
Volume: 10
Issue: 1
Pages: 687
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Publication
33443188 | J:300070
 
First Author: Senda N
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: HMGB1-mediated chromatin remodeling attenuates Il24 gene expression for the protection from allergic contact dermatitis.
Volume: 118
Issue: 1
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Publication
31504280 | J:306386
First Author: Han X
Year: 2020
Journal: Cereb Cortex
Title: PDK1 Regulates Transition Period of Apical Progenitors to Basal Progenitors by Controlling Asymmetric Cell Division.
Volume: 30
Issue: 1
Pages: 406-420
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Publication
34588217 | J:331159
First Author: Inoue T
Year: 2021
Journal: J Immunol
Title: The Loss of H3K27 Histone Demethylase Utx in T Cells Aggravates Allergic Contact Dermatitis.
Volume: 207
Issue: 9
Pages: 2223-2234
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Publication
37685997 | J:340526
 
First Author: Masuda-Kuroki K
Year: 2023
Journal: Int J Mol Sci
Title: S. epidermidis Rescues Allergic Contact Dermatitis in Sphingosine 1-Phosphate Receptor 2-Deficient Skin.
Volume: 24
Issue: 17
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Publication
34537191 | J:343791
First Author: Yip KH
Year: 2022
Journal: J Invest Dermatol
Title: Targeting the Human β(c) Receptor Inhibits Contact Dermatitis in a Transgenic Mouse Model.
Volume: 142
Issue: 4
Pages: 1103-1113.e11
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Protein Coding Gene
MGI:2443187 | Terb1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
28389228 | J:242135
First Author: Rodriguez AM
Year: 2017
Journal: Dev Biol
Title: Brachyury drives formation of a distinct vascular branchpoint critical for fetal-placental arterial union in the mouse gastrula.
Volume: 425
Issue: 2
Pages: 208-222
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Publication
37562754 | J:350478
First Author: Muñoz-Ruiz M
Year: 2023
Journal: J Allergy Clin Immunol
Title: IFN-γ-dependent interactions between tissue-intrinsic γδ T cells and tissue-infiltrating CD8 T cells limit allergic contact dermatitis.
Volume: 152
Issue: 6
Pages: 1520-1540
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Publication
33646289 | J:302837
First Author: Yu X
Year: 2021
Journal: Invest Ophthalmol Vis Sci
Title: Nanophthalmos-Associated MYRF Gene Mutation Causes Ciliary Zonule Defects in Mice.
Volume: 62
Issue: 3
Pages: 1
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Publication
8958812 | J:37119
First Author: Henseleit U
Year: 1996
Journal: J Pathol
Title: E-selectin expression in experimental models of inflammation in mice.
Volume: 180
Issue: 3
Pages: 317-25
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Publication
19191225 | J:146503
First Author: Downs KM
Year: 2009
Journal: Dev Dyn
Title: The Allantoic Core Domain: new insights into development of the murine allantois and its relation to the primitive streak.
Volume: 238
Issue: 3
Pages: 532-53
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Publication
22019303 | J:182719
First Author: Mikedis MM
Year: 2012
Journal: Dev Biol
Title: STELLA-positive subregions of the primitive streak contribute to posterior tissues of the mouse gastrula.
Volume: 363
Issue: 1
Pages: 201-18
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Publication
31234698 | J:329624
First Author: Jung S
Year: 2020
Journal: Autophagy
Title: Autophagic death of neural stem cells mediates chronic stress-induced decline of adult hippocampal neurogenesis and cognitive deficits.
Volume: 16
Issue: 3
Pages: 512-530
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Publication
32452990 | J:343945
First Author: Chen D
Year: 2020
Journal: Cornea
Title: Ocular Manifestations of Chordin-like 1 Knockout Mice.
Volume: 39
Issue: 9
Pages: 1145-1150
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Protein Coding Gene
MGI:107246 | Tinf2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1920086 | Pot1b
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2141503 | Pot1a
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1195972 | Terf2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1929871 | Terf2ip
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:109634 | Terf1
Type: protein_coding_gene
Organism: mouse, laboratory
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