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Search results 201 to 300 out of 767 for Aire

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Type Details Score
Publication
First Author: Morimoto J
Year: 2023
Journal: J Immunol
Title: Cooperative but Distinct Role of Medullary Thymic Epithelial Cells and Dendritic Cells in the Production of Regulatory T Cells in the Thymus.
Volume: 210
Issue: 11
Pages: 1653-1666
Publication
First Author: Yamano T
Year: 2019
Journal: J Exp Med
Title: Aire-expressing ILC3-like cells in the lymph node display potent APC features.
Volume: 216
Issue: 5
Pages: 1027-1037
Publication
First Author: Gavanescu I
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Loss of Aire-dependent thymic expression of a peripheral tissue antigen renders it a target of autoimmunity.
Volume: 104
Issue: 11
Pages: 4583-7
Publication
First Author: Halonen M
Year: 2001
Journal: J Histochem Cytochem
Title: Subcellular location and expression pattern of autoimmune regulator (Aire), the mouse orthologue for human gene defective in autoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APECED).
Volume: 49
Issue: 2
Pages: 197-208
Publication
First Author: Shum AK
Year: 2009
Journal: Sci Transl Med
Title: Identification of an autoantigen demonstrates a link between interstitial lung disease and a defect in central tolerance.
Volume: 1
Issue: 9
Pages: 9ra20
Publication
First Author: Kurisaki H
Year: 2013
Journal: PLoS One
Title: Autoimmune gastro-pancreatitis with anti-protein disulfide isomerase-associated 2 autoantibody in Aire-deficient BALB/cAnN mice.
Volume: 8
Issue: 8
Pages: e73862
Publication
First Author: Tuovinen H
Year: 2009
Journal: Cell Immunol
Title: gammadelta T cells develop independently of Aire.
Volume: 257
Issue: 1-2
Pages: 5-12
Publication
First Author: Su MA
Year: 2008
Journal: J Clin Invest
Title: Mechanisms of an autoimmunity syndrome in mice caused by a dominant mutation in Aire.
Volume: 118
Issue: 5
Pages: 1712-26
Publication    
First Author: Guyon C
Year: 2020
Journal: Elife
Title: Aire-dependent genes undergo Clp1-mediated 3'UTR shortening associated with higher transcript stability in the thymus.
Volume: 9
Publication      
First Author: Heng JS
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Comprehensive analysis of a mouse model of spontaneous uveoretinitis using single-cell RNA sequencing.
Publication
First Author: Ferguson BJ
Year: 2008
Journal: J Biol Chem
Title: AIRE's CARD revealed, a new structure for central tolerance provokes transcriptional plasticity.
Volume: 283
Issue: 3
Pages: 1723-31
Publication
First Author: LaFlam TN
Year: 2015
Journal: J Exp Med
Title: Identification of a novel cis-regulatory element essential for immune tolerance.
Volume: 212
Issue: 12
Pages: 1993-2002
Publication
First Author: Michel C
Year: 2017
Journal: J Immunol
Title: Revisiting the Road Map of Medullary Thymic Epithelial Cell Differentiation.
Volume: 199
Issue: 10
Pages: 3488-3503
Publication
First Author: DeVoss J
Year: 2006
Journal: J Exp Med
Title: Spontaneous autoimmunity prevented by thymic expression of a single self-antigen.
Volume: 203
Issue: 12
Pages: 2727-35
Publication  
First Author: Ferré EMN
Year: 2019
Journal: Sci Transl Med
Title: Lymphocyte-driven regional immunopathology in pneumonitis caused by impaired central immune tolerance.
Volume: 11
Issue: 495
Publication
First Author: Ramsey C
Year: 2006
Journal: Eur J Immunol
Title: Increased antigen presenting cell-mediated T cell activation in mice and patients without the autoimmune regulator.
Volume: 36
Issue: 2
Pages: 305-17
Publication
First Author: Dooley J
Year: 2008
Journal: J Immunol
Title: Alterations of the medullary epithelial compartment in the Aire-deficient thymus: implications for programs of thymic epithelial differentiation.
Volume: 181
Issue: 8
Pages: 5225-32
Publication
First Author: Träger U
Year: 2012
Journal: PLoS One
Title: The immune response to melanoma is limited by thymic selection of self-antigens.
Volume: 7
Issue: 4
Pages: e35005
Publication
First Author: Warren BD
Year: 2019
Journal: Biol Reprod
Title: Autoimmune Regulator is required in female mice for optimal embryonic development and implantation†.
Volume: 100
Issue: 6
Pages: 1492-1504
Publication
First Author: Hässler S
Year: 2006
Journal: Blood
Title: Aire-deficient mice develop hematopoetic irregularities and marginal zone B-cell lymphoma.
Volume: 108
Issue: 6
Pages: 1941-8
Publication
First Author: Zhou D
Year: 2012
Journal: Am J Pathol
Title: Critical involvement of macrophage infiltration in the development of Sjögren's syndrome-associated dry eye.
Volume: 181
Issue: 3
Pages: 753-60
Publication
First Author: Jasti S
Year: 2012
Journal: Biol Reprod
Title: The autoimmune regulator prevents premature reproductive senescence in female mice.
Volume: 86
Issue: 4
Pages: 110
Publication
First Author: Yang S
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Aire's plant homeodomain(PHD)-2 is critical for induction of immunological tolerance.
Volume: 110
Issue: 5
Pages: 1833-8
Publication  
First Author: Almaghrabi S
Year: 2023
Journal: Biomed Res Int
Title: Characterisation of APS-1 Experimental Models Is Crucial for Development of Novel Therapies.
Volume: 2023
Pages: 7960443
Publication
First Author: Venanzi ES
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: The variable immunological self: genetic variation and nongenetic noise in Aire-regulated transcription.
Volume: 105
Issue: 41
Pages: 15860-5
Publication
First Author: Padonou F
Year: 2022
Journal: EMBO Rep
Title: Aire-dependent transcripts escape Raver2-induced splice-event inclusion in the thymic epithelium.
Volume: 23
Issue: 3
Pages: e53576
Publication
First Author: Kuroda N
Year: 2005
Journal: J Immunol
Title: Development of autoimmunity against transcriptionally unrepressed target antigen in the thymus of Aire-deficient mice.
Volume: 174
Issue: 4
Pages: 1862-70
Publication
First Author: Pomié C
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Autoimmune regulator (AIRE)-deficient CD8+CD28low regulatory T lymphocytes fail to control experimental colitis.
Volume: 108
Issue: 30
Pages: 12437-42
Publication
First Author: Pitt LA
Year: 2008
Journal: Eur J Immunol
Title: NKT cell development in the absence of the autoimmune regulator gene (Aire).
Volume: 38
Issue: 10
Pages: 2689-96
Publication
First Author: Kärner J
Year: 2013
Journal: Clin Exp Immunol
Title: Anti-cytokine autoantibodies suggest pathogenetic links with autoimmune regulator deficiency in humans and mice.
Volume: 171
Issue: 3
Pages: 263-72
Publication
First Author: Zhu W
Year: 2011
Journal: Cell Immunol
Title: Overexpressing autoimmune regulator regulates the expression of toll-like receptors by interacting with their promoters in RAW264.7 cells.
Volume: 270
Issue: 2
Pages: 156-63
Publication
First Author: Žumer K
Year: 2012
Journal: Mol Cell Biol
Title: Unmodified histone H3K4 and DNA-dependent protein kinase recruit autoimmune regulator to target genes.
Volume: 32
Issue: 8
Pages: 1354-62
Publication
First Author: St-Pierre C
Year: 2015
Journal: J Immunol
Title: Differential Features of AIRE-Induced and AIRE-Independent Promiscuous Gene Expression in Thymic Epithelial Cells.
Volume: 195
Issue: 2
Pages: 498-506
Publication
First Author: Wang J
Year: 2021
Journal: Sci Immunol
Title: Single-cell multiomics defines tolerogenic extrathymic Aire-expressing populations with unique homology to thymic epithelium.
Volume: 6
Issue: 65
Pages: eabl5053
Publication
First Author: Gray D
Year: 2007
Journal: J Exp Med
Title: Proliferative arrest and rapid turnover of thymic epithelial cells expressing Aire.
Volume: 204
Issue: 11
Pages: 2521-8
Publication  
First Author: Oftedal BE
Year: 2017
Journal: J Autoimmun
Title: T cell receptor assessment in autoimmune disease requires access to the most adjacent immunologically active organ.
Volume: 81
Pages: 24-33
Publication
First Author: Hubert FX
Year: 2009
Journal: J Immunol
Title: Aire-deficient C57BL/6 mice mimicking the common human 13-base pair deletion mutation present with only a mild autoimmune phenotype.
Volume: 182
Issue: 6
Pages: 3902-18
Publication
First Author: Aapola U
Year: 2000
Journal: Genomics
Title: Isolation and initial characterization of a novel zinc finger gene, DNMT3L, on 21q22.3, related to the cytosine-5-methyltransferase 3 gene family.
Volume: 65
Issue: 3
Pages: 293-8
Publication
First Author: Kekäläinen E
Year: 2015
Journal: Immunol Lett
Title: Lymphopenia-induced proliferation in the absence of functional Autoimmune regulator (Aire) induces colitis in mice.
Volume: 167
Issue: 1
Pages: 17-22
Publication    
First Author: Miyao T
Year: 2022
Journal: Elife
Title: Integrative analysis of scRNA-seq and scATAC-seq revealed transit-amplifying thymic epithelial cells expressing autoimmune regulator.
Volume: 11
Publication
First Author: Vijmasi T
Year: 2014
Journal: Invest Ophthalmol Vis Sci
Title: Topical administration of lacritin is a novel therapy for aqueous-deficient dry eye disease.
Volume: 55
Issue: 8
Pages: 5401-9
Publication
First Author: Chen FY
Year: 2017
Journal: PLoS One
Title: Aire-deficient mice provide a model of corneal and lacrimal gland neuropathy in Sjögren's syndrome.
Volume: 12
Issue: 9
Pages: e0184916
Publication  
First Author: Wu G
Year: 2012
Journal: BMC Immunol
Title: DNA methylation profile of Aire-deficient mouse medullary thymic epithelial cells.
Volume: 13
Pages: 58
Publication
First Author: Chin RK
Year: 2006
Journal: J Immunol
Title: Lymphotoxin pathway-directed, autoimmune regulator-independent central tolerance to arthritogenic collagen.
Volume: 177
Issue: 1
Pages: 290-7
Publication  
First Author: Lin J
Year: 2016
Journal: Nat Commun
Title: Increased generation of Foxp3(+) regulatory T cells by manipulating antigen presentation in the thymus.
Volume: 7
Pages: 10562
Publication
First Author: Shi JD
Year: 1999
Journal: Autoimmunity
Title: Chromosomal localization and complete genomic sequence of the murine autoimmune regulator gene (Aire).
Volume: 31
Issue: 1
Pages: 47-53
Publication
First Author: Lkhagvasuren E
Year: 2013
Journal: J Immunol
Title: Lymphotoxin β receptor regulates the development of CCL21-expressing subset of postnatal medullary thymic epithelial cells.
Volume: 190
Issue: 10
Pages: 5110-7
Publication
First Author: Wada N
Year: 2011
Journal: J Invest Dermatol
Title: Aire-dependent thymic expression of desmoglein 3, the autoantigen in pemphigus vulgaris, and its role in T-cell tolerance.
Volume: 131
Issue: 2
Pages: 410-7
Publication
First Author: Martins VC
Year: 2008
Journal: J Immunol
Title: Ltbetar signaling does not regulate Aire-dependent transcripts in medullary thymic epithelial cells.
Volume: 181
Issue: 1
Pages: 400-7
Publication
First Author: Landegren N
Year: 2015
Journal: Sci Transl Med
Title: Transglutaminase 4 as a prostate autoantigen in male subfertility.
Volume: 7
Issue: 292
Pages: 292ra101
Publication
First Author: Shum AK
Year: 2013
Journal: Sci Transl Med
Title: BPIFB1 is a lung-specific autoantigen associated with interstitial lung disease.
Volume: 5
Issue: 206
Pages: 206ra139
Publication
First Author: Brahmaraju M
Year: 2011
Journal: Biochem Cell Biol
Title: AIRE1A might be involved in cyclin B2 degradation in testicular lysates.
Volume: 89
Issue: 4
Pages: 411-22
Publication  
First Author: Chen YT
Year: 2009
Journal: Mol Vis
Title: Immune profile of squamous metaplasia development in autoimmune regulator-deficient dry eye.
Volume: 15
Pages: 563-76
Publication
First Author: Su MA
Year: 2012
Journal: J Immunol
Title: Defective autoimmune regulator-dependent central tolerance to myelin protein zero is linked to autoimmune peripheral neuropathy.
Volume: 188
Issue: 10
Pages: 4906-12
Publication
First Author: Abramson J
Year: 2010
Journal: Cell
Title: Aire's partners in the molecular control of immunological tolerance.
Volume: 140
Issue: 1
Pages: 123-35
Publication
First Author: Tomofuji Y
Year: 2020
Journal: Nat Immunol
Title: Chd4 choreographs self-antigen expression for central immune tolerance.
Volume: 21
Issue: 8
Pages: 892-901
Publication  
First Author: Zhu ML
Year: 2016
Journal: Nat Commun
Title: Sex bias in CNS autoimmune disease mediated by androgen control of autoimmune regulator.
Volume: 7
Pages: 11350
Publication
First Author: Takaba H
Year: 2015
Journal: Cell
Title: Fezf2 Orchestrates a Thymic Program of Self-Antigen Expression for Immune Tolerance.
Volume: 163
Issue: 4
Pages: 975-87
Publication
First Author: Zhu M
Year: 2006
Journal: J Clin Invest
Title: NF-kappaB2 is required for the establishment of central tolerance through an Aire-dependent pathway.
Volume: 116
Issue: 11
Pages: 2964-71
Publication
First Author: Chen Z
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: How defects in central tolerance impinge on a deficiency in regulatory T cells.
Volume: 102
Issue: 41
Pages: 14735-40
Publication
First Author: Dikiy S
Year: 2021
Journal: Immunity
Title: A distal Foxp3 enhancer enables interleukin-2 dependent thymic Treg cell lineage commitment for robust immune tolerance.
Volume: 54
Issue: 5
Pages: 931-946.e11
Publication
First Author: Kekäläinen E
Year: 2015
Journal: Scand J Immunol
Title: Autoimmunity, Not a Developmental Defect, is the Cause for Subfertility of Autoimmune Regulator (Aire) Deficient Mice.
Volume: 81
Issue: 5
Pages: 298-304
Publication
First Author: Li J
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Developmental pathway of CD4+CD8- medullary thymocytes during mouse ontogeny and its defect in Aire-/- mice.
Volume: 104
Issue: 46
Pages: 18175-80
Publication
First Author: McCarthy NI
Year: 2015
Journal: J Immunol
Title: Osteoprotegerin-Mediated Homeostasis of Rank+ Thymic Epithelial Cells Does Not Limit Foxp3+ Regulatory T Cell Development.
Volume: 195
Issue: 6
Pages: 2675-82
Publication
First Author: Bonner SM
Year: 2012
Journal: J Biol Chem
Title: Sequence variation in promoter of Ica1 gene, which encodes protein implicated in type 1 diabetes, causes transcription factor autoimmune regulator (AIRE) to increase its binding and down-regulate expression.
Volume: 287
Issue: 21
Pages: 17882-17893
Publication
First Author: Heino M
Year: 2000
Journal: Eur J Immunol
Title: RNA and protein expression of the murine autoimmune regulator gene (Aire) in normal, RelB-deficient and in NOD mouse.
Volume: 30
Issue: 7
Pages: 1884-93
Publication
First Author: Policheni AN
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: PD-1 cooperates with AIRE-mediated tolerance to prevent lethal autoimmune disease.
Volume: 119
Issue: 15
Pages: e2120149119
Publication
First Author: Ishikawa T
Year: 2023
Journal: Genes Cells
Title: T-cell receptor repertoire analysis of CD4-positive T cells from blood and an affected organ in an autoimmune mouse model.
Volume: 28
Issue: 12
Pages: 929-941
Publication      
First Author: Warren BD
Year: 2021
Journal: Am J Pathol
Title: Multiple Lesions Contribute to Infertility in Males Lacking Autoimmune Regulator.
Publication
First Author: Chen YF
Year: 2014
Journal: Am J Pathol
Title: Spontaneous development of autoimmune uveitis Is CCR2 dependent.
Volume: 184
Issue: 6
Pages: 1695-705
Publication
First Author: Ushio A
Year: 2024
Journal: Cell Rep
Title: Functionally diverse thymic medullary epithelial cells interplay to direct central tolerance.
Volume: 43
Issue: 4
Pages: 114072
Publication
First Author: Michelson DA
Year: 2022
Journal: Cell
Title: Thymic epithelial cells co-opt lineage-defining transcription factors to eliminate autoreactive T cells.
Volume: 185
Issue: 14
Pages: 2542-2558.e18
Publication
First Author: Taniguchi RT
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Detection of an autoreactive T-cell population within the polyclonal repertoire that undergoes distinct autoimmune regulator (Aire)-mediated selection.
Volume: 109
Issue: 20
Pages: 7847-52
Publication
First Author: Zhang X
Year: 2012
Journal: Eur J Immunol
Title: CD24 on thymic APCs regulates negative selection of myelin antigen-specific T lymphocytes.
Volume: 42
Issue: 4
Pages: 924-35
Publication
First Author: Jaini R
Year: 2020
Journal: Hum Mol Genet
Title: Germline PTEN mutations are associated with a skewed peripheral immune repertoire in humans and mice.
Volume: 29
Issue: 14
Pages: 2353-2364
Publication
First Author: McCarron MJ
Year: 2019
Journal: Nat Commun
Title: Transforming Growth Factor-beta signaling in αβ thymocytes promotes negative selection.
Volume: 10
Issue: 1
Pages: 5690
Publication
First Author: Chen YT
Year: 2012
Journal: Lab Invest
Title: Interleukin-1 receptor mediates the interplay between CD4+ T cells and ocular resident cells to promote keratinizing squamous metaplasia in Sjögren's syndrome.
Volume: 92
Issue: 4
Pages: 556-70
Publication
First Author: Devoss JJ
Year: 2008
Journal: J Immunol
Title: Effector mechanisms of the autoimmune syndrome in the murine model of autoimmune polyglandular syndrome type 1.
Volume: 181
Issue: 6
Pages: 4072-9
Publication
First Author: Proekt I
Year: 2016
Journal: J Clin Invest
Title: LYN- and AIRE-mediated tolerance checkpoint defects synergize to trigger organ-specific autoimmunity.
Volume: 126
Issue: 10
Pages: 3758-3771
Publication
First Author: Nakajima A
Year: 2017
Journal: J Immunol
Title: Maternal High Fiber Diet during Pregnancy and Lactation Influences Regulatory T Cell Differentiation in Offspring in Mice.
Volume: 199
Issue: 10
Pages: 3516-3524
Publication
First Author: Laan M
Year: 2009
Journal: J Immunol
Title: Autoimmune regulator deficiency results in decreased expression of CCR4 and CCR7 ligands and in delayed migration of CD4+ thymocytes.
Volume: 183
Issue: 12
Pages: 7682-91
Publication
First Author: Teh CE
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: T-cell regulation by casitas B-lineage lymphoma (Cblb) is a critical failsafe against autoimmune disease due to autoimmune regulator (Aire) deficiency.
Volume: 107
Issue: 33
Pages: 14709-14
Publication
First Author: White AJ
Year: 2008
Journal: Eur J Immunol
Title: Sequential phases in the development of Aire-expressing medullary thymic epithelial cells involve distinct cellular input.
Volume: 38
Issue: 4
Pages: 942-7
Publication
First Author: Saade M
Year: 2010
Journal: Eur J Immunol
Title: Spatial (Tbata) expression in mature medullary thymic epithelial cells.
Volume: 40
Issue: 2
Pages: 530-8
Publication
First Author: Chen YT
Year: 2013
Journal: PLoS One
Title: Pax6 downregulation mediates abnormal lineage commitment of the ocular surface epithelium in aqueous-deficient dry eye disease.
Volume: 8
Issue: 10
Pages: e77286
Publication
First Author: Perry JSA
Year: 2018
Journal: Immunity
Title: Transfer of Cell-Surface Antigens by Scavenger Receptor CD36 Promotes Thymic Regulatory T Cell Receptor Repertoire Development and Allo-tolerance.
Volume: 48
Issue: 5
Pages: 923-936.e4
Publication
First Author: Gruper Y
Year: 2023
Journal: Nature
Title: Autoimmune amelogenesis imperfecta in patients with APS-1 and coeliac disease.
Volume: 624
Issue: 7992
Pages: 653-662
Publication
First Author: Muñoz JJ
Year: 2019
Journal: Histochem Cell Biol
Title: FoxN1 mediates thymic cortex-medulla differentiation through modifying a developmental pattern based on epithelial tubulogenesis.
Volume: 152
Issue: 6
Pages: 397-413
Publication
First Author: Miller CN
Year: 2018
Journal: Nature
Title: Thymic tuft cells promote an IL-4-enriched medulla and shape thymocyte development.
Volume: 559
Issue: 7715
Pages: 627-631
Publication
First Author: Malhotra D
Year: 2016
Journal: Nat Immunol
Title: Tolerance is established in polyclonal CD4(+) T cells by distinct mechanisms, according to self-peptide expression patterns.
Volume: 17
Issue: 2
Pages: 187-95
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory