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Search results 201 to 245 out of 245 for Ak3

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Type Details Score
Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
1639383 | J:1406
First Author: Xu G
Year: 1992
Journal: Genomics
Title: Characterization of human adenylate kinase 3 (AK3) cDNA and mapping of the AK3 pseudogene to an intron of the NF1 gene.
Volume: 13
Issue: 3
Pages: 537-42
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Publication
182062 | J:5678
First Author: Povey S
Year: 1976
Journal: Ann Hum Genet
Title: Evidence for the assignment of the loci AK1, AK3 and ACONs to chromosome 9 in man.
Volume: 39
Issue: 4
Pages: 413-22
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Protein
Q9D8W6
Organism: Mus musculus/domesticus
Length: 189  
Fragment?: false
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Publication
15753074 | -
First Author: Gu Y
Year: 2005
Journal: J Biol Chem
Title: A GTP:AMP phosphotransferase, Adk2p, in Saccharomyces cerevisiae. Role of the C terminus in protein folding/stabilization, thermal tolerance, and enzymatic activity.
Volume: 280
Issue: 19
Pages: 18604-9
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Protein Domain
IPR028586 | AK3/Ak4_mitochondrial
Type: Family
Description: Adenylate kinases (AKs) are nucleoside monophosphate kinases, which catalyse the phosphorylation of AMP by using ATP or GTP as phosphate donors. In humans, nine different AK isoenzymes have been identified (AK1-9). This entry represents AK3/4. Both AK3 and AK4 are localised in the mitochondrial matrix. AK3 is expressed in liver, heart and skeletal muscle, while AK4 is expressed predominantly in kidney []. Despite its homology with AK3, AK4 shows no enzymatic activity in vitro []. AK4 contains an unusual feature of an N-terminal mitochondrial import sequence that remains uncleaved after import into the mitochondria []. This entry also includes yeast mitochondrial adenylate kinase, Adk2. Its 3' sequence varies with strain background [].
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Publication
219990 | J:17652
First Author: Carritt B
Year: 1979
Journal: Cytogenet Cell Genet
Title: Regional asssignments of the loci AK3, ACONS, and ASS on human chromosome 9.
Volume: 23
Issue: 3
Pages: 171-81
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Publication
19766732 | -
First Author: Panayiotou C
Year: 2010
Journal: Int J Biochem Cell Biol
Title: Evidence of an intact N-terminal translocation sequence of human mitochondrial adenylate kinase 4.
Volume: 42
Issue: 1
Pages: 62-9
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Protein Domain
IPR018042 | Aspartate_kinase_CS
Type: Conserved_site
Description: Aspartate kinase () (AK) catalyzes the first reaction in the aspartate pathway; the phosphorylation of aspartate. The product of this reaction can then be used in the biosynthesis of lysine or in the pathway leading to homoserine, which participates in the biosynthesis of threonine, isoleucine and methionine [].In bacteria there are three different aspartate kinase isozymes which differ in sensitivity to repression and inhibition by Lys, Met and Thr. AK1 and AK2 are bifunctional enzymes which both consist of an N-terminal AK domain and a C-terminal homoserine dehydrogenase domain. AK1 is involved in threonine biosynthesis and AK2, in that of methionine. The third isozyme, AK3 is monofunctional and involved in lysine synthesis. In archaea and plants there may be a single isozyme of AK which in plants is multifunctional.This entry represents a region encoding aspartate kinase activity found in both the monofunctional and bifunctional enzymes.Synonym(s): Aspartokinase
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Publication
29769406 | J:265656
First Author: Bond MJ
Year: 2018
Journal: Mol Cancer Res
Title: Spindle Assembly Disruption and Cancer Cell Apoptosis with a CLTC-Binding Compound.
Volume: 16
Issue: 9
Pages: 1361-1372
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Publication
10544043 | J:58396
First Author: Noma T
Year: 1999
Journal: Biochem Biophys Res Commun
Title: Cloning and functional characterization of the promoter region of the gene encoding human adenylate kinase isozyme 3.
Volume: 264
Issue: 3
Pages: 990-7
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Publication
8468325 | J:46604
First Author: Tanabe T
Year: 1993
Journal: J Biochem
Title: Tissue-specific and developmentally regulated expression of the genes encoding adenylate kinase isozymes.
Volume: 113
Issue: 2
Pages: 200-7
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Publication
2892836 | -
First Author: Rafalski JA
Year: 1988
Journal: J Biol Chem
Title: Structure of the yeast HOM3 gene which encodes aspartokinase.
Volume: 263
Issue: 5
Pages: 2146-51
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Publication
9813319 | J:51041
First Author: Yoneda T
Year: 1998
Journal: Brain Res Mol Brain Res
Title: Identification of a novel adenylate kinase system in the brain: cloning of the fourth adenylate kinase.
Volume: 62
Issue: 2
Pages: 187-95
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Protein Domain
IPR001341 | Asp_kinase
Type: Domain
Description: Bacteria, plants and fungi metabolise aspartic acid to produce four amino acids - lysine, threonine, methionine and isoleucine - in a series of reactions known as the aspartate pathway. Additionally, several important metabolic intermediates are produced by these reactions, such as diaminopimelic acid, an essential component of bacterial cell wall biosynthesis, and dipicolinic acid, which is involved in sporulation in Gram-positive bacteria. Members of the animal kingdom do not posses this pathway and must therefore acquire these essential amino acids through their diet. Research into improving the metabolic flux through this pathway has the potential to increase the yield of the essential amino acids in important crops, thus improving their nutritional value. Additionally, since the enzymes are not present in animals, inhibitors of them are promising targets for the development of novel antibiotics and herbicides. For more information see [].Aspartate kinase () (AK) catalyzes the first reaction in the aspartate pathway; the phosphorylation of aspartate. The product of this reaction can then be used in the biosynthesis of lysine or in the pathway leading to homoserine, which participates in the biosynthesis of threonine, isoleucine and methionine [].In bacteria there are three different aspartate kinase isozymes which differ in sensitivity to repression and inhibition by Lys, Met and Thr. AK1 and AK2 are bifunctional enzymes which both consist of an N-terminal AK domain and a C-terminal homoserine dehydrogenase domain. AK1 is involved in threonine biosynthesis and AK2, in that of methionine. The third isozyme, AK3 is monofunctional and involved in lysine synthesis. In archaea and plants there may be a single isozyme of AK which in plants is multifunctional.
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Protein
Q9WTP7
Organism: Mus musculus/domesticus
Length: 227  
Fragment?: false
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Protein
Q9WUR9
Organism: Mus musculus/domesticus
Length: 223  
Fragment?: false
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Protein
Q3UYL0
Organism: Mus musculus/domesticus
Length: 344  
Fragment?: true
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Protein
Q3U489
Organism: Mus musculus/domesticus
Length: 223  
Fragment?: false
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Publication
11352712 | -
First Author: Viola RE
Year: 2001
Journal: Acc Chem Res
Title: The central enzymes of the aspartate family of amino acid biosynthesis.
Volume: 34
Issue: 5
Pages: 339-49
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